seyama kuniaki 瀬山邦明

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SEYAMA Kuniaki 瀬山邦明

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Researcher Number	10226681
Other IDs
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Affiliation (Current)	2025: 順天堂大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2020 – 2024: 順天堂大学, 医学部, 教授 2016 – 2019: 順天堂大学, 医学部, 先任准教授 2010 – 2015: 順天堂大学, 医学部, 准教授 2014: 順天堂大学, 医学部, 専任准教授 2011: 順天堂大学, 医学部, 先任准教授 … More 2009: 順天堂大学, 医学部・呼吸器内科, 准教授 2007 – 2008: Juntendo University, 医学部, 准教授 2006: 順天堂大学, 医学部, 助教授 1999 – 2005: 順天堂大学, 医学部, 講師 2001: 順天堂大学, 呼吸器内科, 講師 1992: 順天堂大学, 呼吸器内科, 助手 1991 – 1992: 順天堂大学, 医学部, 助手 1990: Juntendo Uni. School of Med., Assist., 医学部・呼吸器内科, 助手 1990: 順天堂大学, 医学部呼吸器内科, 助手 Less
Review Section/Research Field	Principal Investigator Respiratory organ internal medicine / Basic Section 53030:Respiratory medicine-related / Respiratory organ internal medicine Except Principal Investigator Respiratory organ internal medicine / Respiratory organ internal medicine / Basic Section 59040:Nutrition science and health science-related / Basic Section 53030:Respiratory medicine-related / Experimental pathology
Keywords	Principal Investigator リンパ脈管筋腫症 / 癌抑制遺伝子 / リンパ管新生 / 結節性硬化症 / TSC遺伝子 / LOH / 遺伝子変異 / TSC2 / 初代培養 / リンパ管内皮細胞 … More / 嚢胞性肺疾患 / 自然気胸 / 分化制御異常 / 間葉系幹細胞 / 腫瘍抑制遺伝子 / 形質転換 / mTORシグナル / 細胞外小胞 / 分子細胞呼吸器学 / 内皮増殖因子 / 分子細胞呼吸器病学 / フローサイトメトリー / 内皮細胞増殖因子 / 内皮間葉転換 / Lymphangiogenesis / Estrogen / Growth inhibitory factor / Growth factor / Primary culture / Tumor suppressor gene / Lymphangioleiomyomatosis / リンパ腫管筋腫症 / 女性ホルモン / 増殖抑制因子 / 増殖因子 / lymphangiogenesis / Fractal / Tuberous sclerosis complex / tumor suppressor gene / germline mutation / The TSC genes / lymphangioleiomyomatosis / TSC1 / フラクタル / 胚細胞遺伝子変異 / 肺リンパ脈管筋腫症 / 蛋白定量 / タンパク定量 / 遺伝子発現 / フォリクリン / ウエスタンブロット法 / ウェスタンブロット法 / folliculin / 生殖細胞系列変異 / FLCN遺伝子 / BHD症候群 / モデル動物 / 腫瘍幹細胞 / LAM細胞 / Folliculin / BHD遺伝子 / Birt-Hogg-Dube症候群 / リンパ行性転移 / がん抑制遺伝子 / 遺伝子導入 / 調節遺伝子 / レトロウイルス / 間質性肺炎 / トランスジェニックマウス / Human Foamy Virus / bel遺伝子 / レトロウィルス / 肺線維症 … More Except Principal Investigator 肺気腫 / SMP30 / COPD / 気道上皮細胞 / Emphysema / 喫煙 / 慢性閉塞性肺疾患(COPD) / 慢性閉塞性肺疾患 / 加熱式タバコ / 気道炎症 / アポトーシス / 加齢 / タバコ煙抽出液 / 気管支洗浄液 / エクソソーム / COX-2 / miR-146a / microRNA / 肺嚢胞 / 肺線維芽細胞 / BHD症候群 / 遺伝子検査 / 気胸 / 嚢胞性肺疾患 / 嚢胞性線維症 / iPS細胞 / 細胞外マトリックス / リンパ脈管筋腫症 / 老化細胞 / 慢性閉塞性肺疾患 (COPD) / マイクロアレイ解析 / DNA傷害 / グリセロール / 新型タバコ / ヒト小気道上皮細胞 / 末梢気道上皮細胞 / プロピレングリコール / PTGS2 (COX-2) / 小気道上皮細胞 / 慢性閉塞性肺疾患（COPD） / 分子細胞呼吸器学 / 疾患モデリング / 肺臓器再生 / 分子細胞呼吸学 / Senescence-accelerated mouse / Aging / Protein modification / Cigarette smoke exposure / Airway Inflammation / 粘液細胞 / ニトロチロシン / 慢性喫煙曝露 / 炎症性サイトカイン / senescence-accelerated mouse / 分子修飾 / 慢性喫煙暴露 / bronchial inflammation / smoke exposure / apoptosis / bronchial epithelial cells / Knockout mice / Ageing / ノックアウトマウス / extra cellular matrix / smoking exposure / Fawn-hooded rat / Lung mechanics / MMP / レチノイド / 喫煙曝露 / FHR / 換気力学 / SSCP / Diffuse panbronchiolitis / Cystic fibrosis / Chloride ion channel / CFTR gene / Respiratory epithelial cell / SSCP法 / びまん性汎細気管支炎 / 塩素イオンチャンネル / CFTR遺伝子 / allele specific PCR / polymerase chain reaction / sequencing / missense mutation / protease-antiprotease balance / pulmonary emphysema / deficiency / alpha1-antitrypsin / 分子生物学 / 蛋白分解酵素一阻害物質均衡 / ポリメラ-ゼ・チェイン・リアクション(PCR) / 塩基配列解読 / ミスセンス変異 / α1ーアンチトリプシン遺伝子異常 / 蛋白分解酵素ー阻害物質均衡 / 肺末梢気腔破壊 / α1ーアンチトリプシン欠損症 / SMP30ノックアウトマウス / NF-kB / COPD増悪 / IL-8 / 炎症 / フォリキュリン(Folliculin/FLCN) / Birt-Hogg-Dube症候群(BHD症候群) / Birt-Hogg-Dube症候群 / 分化誘導 / I型肺胞上皮細胞 / 疾患特異的iPS / 若年性肺気腫 / 特発性間質性肺炎 / 肺胞上皮細胞 / 疾患特異iPS / Hermansky-Pudlak 症候群 / ３次元培養 / carboxypeptidase M / surfactant protein C / II型肺胞上皮細胞 / ES細胞 / 接着因子 / LAM cell cluster(LCC) / 肺リンパ脈管筋腫症 / 細胞接着分子 / リンパ内皮細胞 / リンパ増殖因子 / リンパ脈管筋腫症細胞集塊 / 感受性因子 / 疫学調査 / α1-アンチトリプシン欠損症 Less

老化細胞に着目した加熱式タバコによる肺気腫の発症機序解明と治療戦略の提唱
- Principal Investigator
  
  佐藤匡
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Juntendo University
リンパ脈管筋腫症は神経堤由来間葉系幹細胞が分化制御異常を来した疾患であるPrincipal Investigator
- Principal Investigator
  
  瀬山邦明
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Juntendo University
慢性タバコ煙曝露システムを用いた加熱式タバコエアロゾルによる肺傷害の解析
- Principal Investigator
  
  佐藤匡
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Juntendo University
The role of extracellular vesicles in the pathobiology of lymphangioleiomyomatosisPrincipal Investigator
- Principal Investigator
  
  SEYAMA KUNIAKI
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Juntendo University
Airway secreted exosome as a novel therapeutic target for Chronic Obstructive Pulmonary Disease (COPD)
- Principal Investigator
  
  Sato Tadashi
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Juntendo University
Investigation on the endothelial-mesenchymal transition in lymphangioleiomyomatosisPrincipal Investigator
- Principal Investigator
  
  Seyama Kuniaki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Juntendo University
Application of iPS cell technology to lung regeneration and development of bioresource for elucidating the mechanisms of lung diseases
- Principal Investigator
  
  Michiaki Mishima
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Kyoto University
MicroRNAs associated with smoking-induced pulmonary emphysema in senescence marker protein-30 knockout mice
- Principal Investigator
  
  Sato Tadashi
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Juntendo University
To develop a novel method to establish the diagnosis of BHD syndromePrincipal Investigator
- Principal Investigator
  
  SEYAMA KUNIAKI
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Juntendo University
Study on the germline FLCN mutations and the mechanism of pulmonary cyst formation in Birt-Hogg-Dube syndrome
- Principal Investigator
  
  KIKKAWA MIKA
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Juntendo University
Researches using iPS cells on intractable respiratory diseases to elucidate their pathogenesis and develop novel therapy.
- Principal Investigator
  
  MISHIMA MICHIAKI
- Project Period (FY)
  2010 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Kyoto University
Study on the germline FLCN mutations and the mechanism of pulmonary cyst formation in Birt-Hogg-Dube syndrome
- Principal Investigator
  
  KIKKAWA Mika
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Juntendo University
Isolation of LAM stem cells and its application for the establishment of mouse LAM model.Principal Investigator
- Principal Investigator
  
  SEYAMA Kuniaki
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Juntendo University
Elucidation of the mechanism for cell adhesion between LAM cells and lymphatic endothelial cells in the LAM cell clusters
- Principal Investigator
  
  KUMASAKA Toshio
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Juntendo University
Study on the mechanism of LAM cell proliferation and disease progression in lymphangioleiomyomatosisPrincipal Investigator
- Principal Investigator
  
  SEYAMA Kuniaki
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Juntendo University
多発性嚢胞性肺疾患におけるBHD遺伝子解析-嚢胞形成の分子病因的検討-Principal Investigator
- Principal Investigator
  
  瀬山邦明
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Juntendo University
Mechanisms of proliferation and metastasis of LAM cells in lymphangioleiomyomatosis (LAM)Principal Investigator
- Principal Investigator
  
  SEYAMA Kuniaki
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Juntendo University
Analysis of airway inflammation and remodeling induced by chronic cigarette smoke exposure in mice lungs.
- Principal Investigator
  
  FUKUCHI Yoshinosuke
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  JUNTENDO UNIVERSITY
Comprehensive analysis of pathogenesis in lymphangioleiomyomatosisPrincipal Investigator
- Principal Investigator
  
  SEYAMA Kuniaki
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  JUNTENDO UNIVERSITY
Cigarette smoke-induced lung pathology in SMP30 knockout mice
- Principal Investigator
  
  FUKUCHI Yoshinosuke
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  JUNTENDO UNIVERSITY
レトロウイルス調節遺伝子bel geneを用いた肺線維症実験モデル動物の作製Principal Investigator
- Principal Investigator
  
  瀬山邦明
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Juntendo University
アジアにおける肺気腫およびα1アンチトリプシン欠損型亜型Siiyamaの疫学調査
- Principal Investigator
  
  FUKUCHI Yoshinosuke
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Juntendo University
Molecular and genetic studies on patho genesis and patho plrysiolegy of emphysema
- Principal Investigator
  
  FUKUCHI Yoshinosuke
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  JUNTENDO UNIVERSITY
Analysis of cystic fibrosis transmembrane conductance regulator gene in patients with diffuse panbronchiolitis.
- Principal Investigator
  
  NUKIWA Toshihiro
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Juntendo University School of Medicine
Direct Search for Nucleotide Substitutions Responsible for Defects of Alpha 1-Antitrypsin Molecules in Patients with Pulmonary Emphysema.
- Principal Investigator
  
  NUKIWA Toshihiro
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Juntendo University School of Medicine

[Book] Chronic Obstructive Pulmonary Disease A Systemic Inflammatory Disease2017
- Author(s)
  Tadashi Sato, Kuniaki Seyama
- Total Pages
  352
- Publisher
  Springer
- ISBN
  9789811008382
- Data Source
  KAKENHI-PROJECT-17K09668
[Book] Chronic Obstructive Pulmonary Disease. A Systemic Inflammatory Disease2017
- Author(s)
  Sato T, Seyama K
- Total Pages
  352
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-26461199
[Book] Chronic Obstructive Pulmonary Disease A Systemic Inflammatory Disease2017
- Author(s)
  Sato T, Seyama K
- Total Pages
  352
- Publisher
  Springer
- ISBN
  9789811008382
- Data Source
  KAKENHI-PROJECT-26461199
[Book] Lymphangioleiomyomatosis : In Lymphangiogenesis and Cancer Metastasis2009
- Author(s)
  Seyama K. Kumasaka T, Sato T, Mitani K.
- Publisher
  Springer London(In press)
- Data Source
  KAKENHI-PROJECT-19590406
[Book] 今日の治療指針;肺リンパ脈管筋腫症(山口徹, 北原光夫、総編集)2005
- Author(s)
  瀬山邦明
- Publisher
  医学書院
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590762
[Book] 臨床に直結する呼吸器疾患治療のエピデンス;LAMホルモン療法(長瀬隆英, 大石展也編集)2005
- Author(s)
  瀬山邦明
- Publisher
  文光堂
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590762
[Book] 呼吸器疾患ガイドライン最新の診療指針リンパ脈管筋腫症(松岡健編集)2004
- Author(s)
  井上恵美, 佐藤輝彦, 瀬山邦明
- Publisher
  総合医学社
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590762
[Book] 呼吸器疾患の最新の治療 2004-2006;リンパ脈管筋腫症(工藤翔二, 中田紘一郎, 貫和敏博、編集)2004
- Author(s)
  平間未知大, 瀬山邦明
- Publisher
  南江堂
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590762
[Book] Stacker SD and Achen MG
- Author(s)
  Seyama K, Kumasaka T, Sato T, and Mitani K
- Publisher
  Chapter 8. Lymphangioleiomyomatosis. In : Cancer and lymphatic metastasis
- Data Source
  KAKENHI-PROJECT-18390243
[Book] Lymphangioleiomyomatosis. Lymphangiogenesis and Cancer Metastasis. Edited by Stacker SA and Achen MG
- Author(s)
  Seyama K. Kumasaka T, Sato T, Mitani K
- Publisher
  Springer London(in press)
- Data Source
  KAKENHI-PROJECT-19590406
[Journal Article] Exposure to the heated tobacco product IQOS generates apoptosis-mediated pulmonary emphysema in murine lungs2022
- Author(s)
  Nitta Naoko Arano、Sato Tadashi、Komura Moegi、Yoshikawa Hitomi、Suzuki Yohei、Mitsui Aki、Kuwasaki Eriko、Takahashi Fumiyuki、Kodama Yuzo、Seyama Kuniaki、Takahashi Kazuhisa
- Journal Title
  
  American Journal of Physiology-Lung Cellular and Molecular Physiology
  
  Volume: 322 Issue: 5 Pages: L699-L711
- DOI
  10.1152/ajplung.00215.2021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08575, KAKENHI-PROJECT-22K16178
[Journal Article] Propylene glycol, a component of electronic cigarette liquid, damages epithelial cells in human small airways2022
- Author(s)
  Komura Moegi、Sato Tadashi、Yoshikawa Hitomi、Nitta Naoko Arano、Suzuki Yohei、Koike Kengo、Kodama Yuzo、Seyama Kuniaki、Takahashi Kazuhisa
- Journal Title
  
  Respiratory Research
  
  Volume: 23 Issue: 1 Pages: 216-216
- DOI
  10.1186/s12931-022-02142-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08575, KAKENHI-PROJECT-22K16178
[Journal Article] Lung Fixation under Constant Pressure for Evaluation of Emphysema in Mice2019
- Author(s)
  Karasutani Keiko、Baskoro Hario、Sato Tadashi、Arano Naoko、Suzuki Yohei、Mitsui Aki、Shimada Naoko、Kodama Yuzo、Seyama Kuniaki、Fukuchi Yoshinosuke、Takahashi Kazuhisa
- Journal Title
  
  Journal of Visualized Experiments
  
  Volume: 151 Issue: 151
- DOI
  10.3791/58197
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09668
[Journal Article] Regional heterogeneity in response of airway epithelial cells to cigarette smoke2018
- Author(s)
  Baskoro H, Sato T, Karasutani K, Suzuki Y, Mitsui A, Arano N, Nurwidya F, Kato M, Takahashi F, Kodama Y, Seyama K, Takahashi K
- Journal Title
  
  BMC Pulm Med
  
  Volume: 18 Issue: 1 Pages: 148-148
- DOI
  10.1186/s12890-018-0715-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09668
[Journal Article] Hydrogen-rich pure water prevents cigarette smoke-induced pulmonary emphysema in SMP30 knockout mice2017
- Author(s)
  Suzuki Yohei、Sato Tadashi、Sugimoto Masataka、Baskoro Hario、Karasutani Keiko、Mitsui Aki、Nurwidya Fariz、Arano Naoko、Kodama Yuzo、Hirano Shin-ichi、Ishigami Akihito、Seyama Kuniaki、Takahashi Kazuhisa
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 492 Issue: 1 Pages: 74-81
- DOI
  10.1016/j.bbrc.2017.08.035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08604, KAKENHI-PROJECT-17K09668, KAKENHI-PROJECT-15H04505, KAKENHI-PROJECT-26461199
[Journal Article] Antioxidant nutrients in plasma of Japanese patients with chronic obstructive pulmonary disease, asthma-COPD overlap syndrome, and bronchial asthma2016
- Author(s)
  Kodama Y, Kishimoto Y, Muramatsu Y, Tatebe J, Yamamoto Y, Hirota N, Itoigawa Y, Atsuta R, Koike K, Sato T, Aizawa K, Takahashi K, Morita T, Homma S, Seyama K, Ishigami A.
- Journal Title
  
  Clin Respir J
  
  Volume: ー Issue: 6 Pages: 1-10
- DOI
  10.1111/crj.12436
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461199, KAKENHI-PROJECT-14J07562, KAKENHI-PROJECT-15H04505
[Journal Article] MicroRNAs as Therapeutic Targets in Lung Disease: Prospects and Challenges2016
- Author(s)
  Sato T, Baskoro H, Rennard SI, Seyama K, Takahashi K.
- Journal Title
  
  Chronic Obstr Pulm Dis (Miami)
  
  Volume: 3 Issue: 1 Pages: 382-388
- DOI
  10.15326/jcopdf.3.1.2015.0160
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461199
[Journal Article] バート・ホッグ・デュベ症候群2015
- Author(s)
  福岡みずき、江花弘基、岩渕千雅子、栗原正利、瀬山邦明
- Journal Title
  
  日本臨床
  
  Volume: 73 Pages: 64-69
- Data Source
  KAKENHI-PROJECT-25670402
[Journal Article] 診断メモ BHD症候群2015
- Author(s)
  柳下薫寛、瀬山邦明
- Journal Title
  
  内科
  
  Volume: 115 Pages: 931-931
- Data Source
  KAKENHI-PROJECT-25670402
[Journal Article] Characterization of pulmonary cysts in Birt-Hogg-Dube syndrome: histopathological and morphometric analysis of 229 pulmonary cysts from 50 unrelated patients2014
- Author(s)
  Kumasaka T, Hayashi T, Mitani K, Kataoka H, Kikkawa M, Tobino K, Kobayashi E, Gunji Y, Kunogi M, Kurihara M, Seyama K.
- Journal Title
  
  Histopathology
  
  Volume: published online: 4 MAR 2014 Issue: 1 Pages: 1-11
- DOI
  10.1111/his.12368
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24591177, KAKENHI-PROJECT-25670402
[Journal Article] Vitamin C Prevents Cigarette Smoke-Induced Pulmonary Emphysema in Mice and Provides Pulmonary Restoration.2014
- Author(s)
  Koike K, Ishigami A, Sato Y, Hirai T, Yuan Y, Kobayashi E, Tobino K, Sato T, Sekiya M, Takahashi K, Fukuchi Y, Maruyama N, Seyama K.
- Journal Title
  
  Am J Respir Cell Mol Biol.
  
  Volume: 50 Issue: 2 Pages: 347-357
- DOI
  10.1165/rcmb.2013-0121oc
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790922, KAKENHI-PROJECT-24380073, KAKENHI-PROJECT-26461199
[Journal Article] The discovery of a Persian family with a form of Birt-Hogg-Dube syndrome lacking the typical cutaneous stigmata of the syndrome.2013
- Author(s)
  Babaei Jandaghi A, Daliri S, Kikkawa M, Khaledi M, Soleimanifar N, Alizadeh A, Habibzadeh M, Haghi-Ashtiani MT, Seyama K, Rezaei N.
- Journal Title
  
  Clinical Imaging
  
  Volume: 37(1) Issue: 1 Pages: 111-115
- DOI
  10.1016/j.clinimag.2012.03.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591177
[Journal Article] 新しい局面を迎えたLAM治療2012
- Author(s)
  安藤克利, 瀬山邦明
- Journal Title
  
  Annual Review呼吸器
  
  Volume: 2012 Pages: 199-208
- Data Source
  KAKENHI-PROJECT-21659210
[Journal Article] リンパ脈管筋腫症とはCOPDとの鑑別が重要2012
- Author(s)
  安藤克利, 市川昌子, 瀬山邦明
- Journal Title
  
  Medicina
  
  Volume: 49 Pages: 420-423
- Data Source
  KAKENHI-PROJECT-21659210
[Journal Article] リンパ脈管筋腫症2011
- Author(s)
  瀬山邦明
- Journal Title
  
  日本医事新報
  
  Volume: 4540 Pages: 69-76
- NAID
  10031130673
- Data Source
  KAKENHI-PROJECT-21659210
[Journal Article] リンパ脈管筋腫症の病態と治療2011
- Author(s)
  安藤克利, 瀬山邦明
- Journal Title
  
  最新医学
  
  Volume: 66 Pages: 1851-1859
- NAID
  40018951704
- Data Source
  KAKENHI-PROJECT-21659210
[Journal Article] 厚生労働省難治性疾患克服研究事業呼吸不全に関する調査研究班.特定疾患治療研究事業対象疾患リンパ脈管筋腫症(LAM)認定基準の解説2011
- Author(s)
  林田美江, 瀬山邦明, 井上義一, 平井豊博, 三嶋理晃
- Journal Title
  
  日本呼吸器学会雑誌
  
  Volume: 49 Pages: 67-74
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659210
[Journal Article] Prevalence of Uterine and Adnexal Involvement in Pulmonary Lymphangioleiomyomatosis : A Clinicopathologic Study of 10 Patients2011
- Author(s)
  Hayashi T, Kumasaka T, Mitani K, Terao Y, Watanabe M, Oide T, Nakatani Y, Hebisa) a A, Konno R, Takahashi K, Yao T, Seyama K
- Journal Title
  
  Am J Surg Pathol
  
  Volume: 35 Pages: 1776-1785
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659210
[Journal Article] リンパ脈管筋腫症(LAM)2011
- Author(s)
  安藤克利, 瀬山邦明
- Journal Title
  
  綜合臨床
  
  Volume: 60 Pages: 2500-2510
- Data Source
  KAKENHI-PROJECT-21659210
[Journal Article] 治療の進歩新しい局面を迎えたLAM治療2011
- Author(s)
  安藤克利、瀬山邦明
- Journal Title
  
  Annual Review呼吸器2012
  
  Pages: 2500-2510
- Data Source
  KAKENHI-PROJECT-21659210
[Journal Article] LAMの病像2011
- Author(s)
  佐藤輝彦, 飛野和則, 瀬山邦明
- Journal Title
  
  日本胸部臨床
  
  Volume: 70 Pages: 1007-1016
- Data Source
  KAKENHI-PROJECT-21659210
[Journal Article] Characteristics of pulmonary cysts in Birt-Hogg-Dube syndrome : Thin-Section CT findings of the chest in 12 patients2011
- Author(s)
  Koike, K., Tomiyama, T., Johkoh, T., Kodama, Y., Sasaki, S., Kikkawa, M., Takahashi, K., Seyama, K.
- Journal Title
  
  Eur J Radiol
  
  Volume: 77(3) Pages: 403-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790767
[Journal Article] Differentiation between Birt-Hogg-Dube syndrome and lymphangioleiomyomatosis : Quantitative analysis of pulmonary cysts on computed tomography of the chest in 66 females2011
- Author(s)
  Tobino K, Hirai T, Johkoh T, Kurihara M, Fujimoto K, Tomiyama N, Mishima M, Takahashi K, Seyama K
- Journal Title
  
  Eur J Radiol
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659210
[Journal Article] 診断メモリンパ脈管筋腫症2010
- Author(s)
  瀬山邦明
- Journal Title
  
  内科
  
  Volume: 105 Pages: 974-974
- Data Source
  KAKENHI-PROJECT-21659210
[Journal Article] Clinical and genetic spectrum of Birt-Hogg-Dube syndrome patients in whom pneumothorax and/or multiple lung cysts are the presenting feature2010
- Author(s)
  Kunogi, M., Kurihara, M., Shigihara Ikegami, T., Kobayashi, T., Shindo, N., Kumasaka, T., Gunji, Y., Kikkawa, M., Iwakami, S., Hino, O., Takahashi, K., Seyama, K.
- Journal Title
  
  Journal of Medical Genetics
  
  Volume: 47(4) Pages: 281-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790767
[Journal Article] リンパ脈管筋腫症(LAM)における細胞増殖メカニズム2010
- Author(s)
  佐藤輝彦, 瀬山邦明
- Journal Title
  
  THE LUNG-perspectives
  
  Volume: 18 Pages: 141-145
- Data Source
  KAKENHI-PROJECT-21659210
[Journal Article] LAMの病因論2010
- Author(s)
  瀬山邦明
- Journal Title
  
  呼吸と循環
  
  Volume: 58 Pages: 1201-1210
- Data Source
  KAKENHI-PROJECT-21659210
[Journal Article] リンパ脈管筋腫症(LAM)薬シロリムス(ラパミューン)2010
- Author(s)
  瀬山邦明
- Journal Title
  
  日本内科学会雑誌
  
  Volume: 99 Pages: 1617-1622
- Data Source
  KAKENHI-PROJECT-21659210
[Journal Article] リンパ系疾患としてのリンパ脈管筋腫症(LAM)2010
- Author(s)
  瀬山邦明
- Journal Title
  
  呼吸
  
  Volume: 29 Pages: 296-304
- Data Source
  KAKENHI-PROJECT-21659210
[Journal Article] リンパ脈管筋腫症2010
- Author(s)
  星加義人、瀬山邦明
- Journal Title
  
  成人病と生活習慣病
  
  Volume: 40 Pages: 693-698
- NAID
  10031130673
- Data Source
  KAKENHI-PROJECT-21659210
[Journal Article] リンパ脈管筋腫症(LAM)薬シロリムス(ラパミューン)2010
- Author(s)
  瀬山邦明
- Journal Title
  
  日本内科学会雑誌
  
  Volume: 99 Pages: 1617-1622
- Data Source
  KAKENHI-PROJECT-21659210
[Journal Article] Matrix metalloproteinases in blood from patients with LAM2009
- Author(s)
  Odajima N, Betsuyaku T, Nasuhara Y, Inoue H, Seyama K, Nishimura M
- Journal Title
  
  Respir Med 103
  
  Pages: 124-129
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390243
[Journal Article] Peritoneovenous shunting for intractable chylous ascites complicated with lymphangioleiomyoma-tosis2008
- Author(s)
  Makino Y, Shimanuki Y, Fujiwara N, Morio Y, Sato K, Yoshimoto J, Gunji Y, Suzuki T, Sasaki S, Iwase A, Kawasaki S, Takahashi K, Seyama K
- Journal Title
  
  Intern Med 47
  
  Pages: 281-285
- NAID
  130000079736
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390243
[Journal Article] Sirolimus amelioration of clinical symptoms of recurrent lymphangioleiomyomatosis after living-donor lobar lung transplantation2008
- Author(s)
  Sugimoto R, Nakao A, Yamane M, Toyooka S, Okazaki M, Aoe M, Seyama K, Date H, Oto T, Sano Y
- Journal Title
  
  J Heart Lung Transplant 27
  
  Pages: 921-924
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390243
[Journal Article] LAMは腫瘍か2007
- Author(s)
  瀬山邦明, 他
- Journal Title
  
  呼吸 26
  
  Pages: 23-30
- Data Source
  KAKENHI-PROJECT-19590406
[Journal Article] Lymphangioleiomyomatosis diagnosed by immunocytochemical and genetic analysis of lymphangioleiomyomatosis cell clusters found in chylous pleural effusion2007
- Author(s)
  Hirama M, Atsuta R, Mitani K, Kumasaka T, Gunji Y, Sasaki S, Iwase A, Takahashi K, Seyama K
- Journal Title
  
  Intern Med 46
  
  Pages: 1593-6
- NAID
  130000076007
- Data Source
  KAKENHI-PROJECT-19590406
[Journal Article] LAMは腫瘍か?2007
- Author(s)
  瀬山邦明, 熊坂利夫ら
- Journal Title
  
  呼吸 26
  
  Pages: 23-30
- Data Source
  KAKENHI-PROJECT-18390243
[Journal Article] Lymphangioleiomyomatosis diagnosed by immunocytochemical and genetic analysis of lymphangioleiomyoma-tosis cell clusters found in chylous pleural effusion2007
- Author(s)
  Hirama M, Atsuta R, Mitani K, Kumasaka T, Gunji Y, Sasaki S, Iwase A, TakahashiK, Seyama K
- Journal Title
  
  Intern Med 46
  
  Pages: 1593-1596
- NAID
  130000076007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390243
[Journal Article] Respiratory Failure Research Group of the Japanese Ministry of Health, Labor, and Welfare2007
- Author(s)
  Hayashida M, Seyama K, Inoue Y, Fujimoto K, Kubo K
- Journal Title
  
  The epidemiology of lymphangioleiomyomatosisin Japan : a nationwide cross-sectionalstudy of presenting features andprognostic factors 12
  
  Pages: 523-530
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390243
[Journal Article] リンパ脈管筋腫症-TSC遺伝子解析からLAMの進展機序への展開-2006
- Author(s)
  瀬山邦明, 熊坂利夫
- Journal Title
  
  二本内科学会雑誌 95
  
  Pages: 1048-1057
- NAID
  10018198718
- Data Source
  KAKENHI-PROJECT-18390243
[Journal Article] 嚢胞性肺疾患-Birt-Hogg-Dube症候群-2006
- Author(s)
  郡司陽子, 瀬山邦明ら
- Journal Title
  
  分子呼吸器病 10
  
  Pages: 464-467
- Data Source
  KAKENHI-PROJECT-18659242
[Journal Article] Vascular endothelial growth factor-D is increased in serum of patients with lymphangioleiomyomatosis2006
- Author(s)
  Seyama K, Kumasaka T, Souma S, Sato T, Kurihara M, Mitani K, Tominaga S, Fukuchi Y
- Journal Title
  
  Lymphat Res Biol 4
  
  Pages: 143-52
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390243
[Journal Article] 肺リンパ脈管筋腫症の病理と病態2006
- Author(s)
  熊坂利夫, 瀬山邦明ら
- Journal Title
  
  病理と臨床 24
  
  Pages: 939-948
- Data Source
  KAKENHI-PROJECT-18390243
[Journal Article] 質疑応答Q&A「肺リンパ脈管筋腫症の診断、特に画像上の特徴を」2005
- Author(s)
  瀬山邦明
- Journal Title
  
  日本医事新報 No.4248
  
  Pages: 89-90
- Data Source
  KAKENHI-PROJECT-16590762
[Journal Article] LAMの遺伝子異常と病態とのかかわりをみる.分子呼吸器病2005
- Author(s)
  瀬山邦明
- Journal Title
  
  分子呼吸器病 9
  
  Pages: 31-37
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590762
[Journal Article] 講座「画像診断」リンパ脈管筋腫症(2)-進行期-2005
- Author(s)
  佐藤輝彦, 井上恵美, 瀬山邦明
- Journal Title
  
  呼吸 24
  
  Pages: 320-324
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590762
[Journal Article] Lymphangiogenesis-Mediated Shedding of LAM Cell Clusters as a Mechanism for Dissemination in Lymphangioleiomyomatosis.2005
- Author(s)
  Kumasaka T, Seyama K et al.
- Journal Title
  
  American Journal of Surgical Pathology 29
  
  Pages: 1356-1366
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590762
[Journal Article] 講座「画像診断」リンパ脈管筋腫症(2)-初期-2005
- Author(s)
  佐藤輝彦, 井上恵美, 瀬山邦明
- Journal Title
  
  呼吸 (印刷中)
- Data Source
  KAKENHI-PROJECT-16590762
[Journal Article] COPDとLAM診断上の問題点2005
- Author(s)
  井上恵美, 佐藤輝彦, 瀬山邦明
- Journal Title
  
  化学療法の領域 (印刷中)
- Data Source
  KAKENHI-PROJECT-16590762
[Journal Article] COPDとLAM診断上の問題点2005
- Author(s)
  井上恵美, 佐藤輝彦, 瀬山邦明
- Journal Title
  
  化学療法の領域 21増刊号
  
  Pages: 96-104
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590762
[Journal Article] 講座「画像診断」リンパ脈管筋腫症(2)-進行期-2005
- Author(s)
  佐藤輝彦, 井上恵美, 瀬山邦明
- Journal Title
  
  呼吸 (印刷中)
- Data Source
  KAKENHI-PROJECT-16590762
[Journal Article] 質疑応答Q&A 肺リンパ脈管筋腫症の診断、特に画像上の特徴を2005
- Author(s)
  瀬山邦明
- Journal Title
  
  日本医事新報 No.4248
  
  Pages: 89-90
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590762
[Journal Article] Lymphangiogenesis-Mediated Shedding of LAM Cell Clusters as a Mechanism for Dissemination in Lymphangioleiomyomatosis.2005
- Author(s)
  Kumasaka T, Seyama K et al.
- Journal Title
  
  Am J Surg Pathol 29
  
  Pages: 1356-1366
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590762
[Journal Article] 講座「画像診断」リンパ脈管筋腫症(2)-初期-2005
- Author(s)
  佐藤輝彦, 井上恵美, 瀬山邦明
- Journal Title
  
  呼吸 24
  
  Pages: 315-319
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590762
[Journal Article] 患者から医師へのシグナル"LAMって何?"から1年半2004
- Author(s)
  瀬山邦明
- Journal Title
  
  THE LUNG perspectives 12
  
  Pages: 93-96
- Data Source
  KAKENHI-PROJECT-16590762
[Journal Article] A patient with TSC1 germline mutation whose clinical phenotype was limited to lymphangioleiomyomatosis2004
- Author(s)
  Sato T, Seyama K et al.
- Journal Title
  
  Journal of Internal Medicine 256
  
  Pages: 166-173
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590762
[Journal Article] 日常診療におけるGOLDの位置付け2004
- Author(s)
  笠木聡, 瀬山邦明, 福地義之助
- Journal Title
  
  内科 93
  
  Pages: 5-9
- Data Source
  KAKENHI-PROJECT-15390259
[Journal Article] Microdissection法2004
- Author(s)
  瀬山邦明
- Journal Title
  
  分子呼吸器病 8
  
  Pages: 66-69
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590762
[Journal Article] Senescence marker protein-30 knockout mouse as a novel murine model of senile lung.2004
- Author(s)
  Mori T, Ishigami A, Seyama K et al.
- Journal Title
  
  Pathology International 54
  
  Pages: 167-173
- NAID
  10013056213
- Data Source
  KAKENHI-PROJECT-15390259
[Journal Article] リンパ脈管筋腫症とTSC遺伝子2004
- Author(s)
  瀬山邦明, 他
- Journal Title
  
  呼吸器科 6
  
  Pages: 457-463
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590762
[Journal Article] 肺リンパ脈管筋腫症2004
- Author(s)
  高木裕美子, 佐藤輝彦, 瀬山邦明
- Journal Title
  
  COPD Frontier 3
  
  Pages: 33-37
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590762
[Journal Article] リンパ脈管筋腫症(LAM)2004
- Author(s)
  佐藤輝彦, 瀬山邦明
- Journal Title
  
  呼吸器科 5
  
  Pages: 118-126
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590762
[Journal Article] 患者から医師へのシグナル."LAMって何?"から1年半2004
- Author(s)
  瀬山邦明
- Journal Title
  
  THE LUNG perspectives 12
  
  Pages: 93-96
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590762
[Journal Article] Lymphangiogenesis in lymphangioleiomyomatosis : its implication in the progression of lymphangioleiomyomatosis 1007-1016.2004
- Author(s)
  Kumasaka T, Seyama K et al.
- Journal Title
  
  American Journal of Surgical Pathology 28
  
  Pages: 1007-1016
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590762
[Journal Article] Lymphangiogenesis in lymphangioleiomyomatosis : its implication in the progression of lymphangioleiomyomatosis 1007-1016.2004
- Author(s)
  Kumasaka T, Seyama K et al.
- Journal Title
  
  American journal of Surgical Pathology 28
  
  Pages: 1007-1016
- Data Source
  KAKENHI-PROJECT-16590762
[Journal Article] リンパ脈管筋腫症2004
- Author(s)
  瀬山邦明, 他
- Journal Title
  
  家族性腫瘍 4
  
  Pages: 18-24
- NAID
  10031130673
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590762
[Journal Article] リンパ脈管筋腫症2004
- Author(s)
  佐藤輝彦, 瀬山邦明
- Journal Title
  
  臨床放射線 49
  
  Pages: 9-19
- NAID
  10031130673
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590762
[Journal Article] Cytological, Immunocytochemical, and Ultrastructural Characterization of LAM Cell Clusters in the Chylous Effusion of Patients with Lymphangioleiomyomatosis
- Author(s)
  Mitani K, Kumasaka T, Takemura H, Hayashi T, Gunji Y, Kunogi M, Akiyoshi T, Takahashi K, Suda K, Seyama K
- Journal Title
  
  ActaCytologica (in press)
- Data Source
  KAKENHI-PROJECT-19590406
[Journal Article] Cytological, immunocytochemical, and ultrastructural characterization of LAM cell clusters in chylous effusion of patients with lymphangioleiomyomatosis
- Author(s)
  Mitani K, Kumasaka T, Takemura H, Hayashi T, Gunji Y, Kunogi M, Akiyoshi T, Takahashi K, Suda K, Seyama K
- Journal Title
  
  Acta Cytologica (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390243
[Presentation] 加熱式タバコIQOSの慢性曝露はマウス肺においてアポトーシスと肺気腫を誘導する2023
- Author(s)
  新田(荒野)直子、佐藤匡、小村萌起、吉川仁美、鈴木洋平、三井亜樹、鍬崎恵里子、高橋史行、児玉裕三、瀬山邦明、髙橋和久
- Organizer
  第63回日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-20K08575
[Presentation] Propylene glycol, a component of electronic cigarette liquid, damages epithelial cells in human small airways2023
- Author(s)
  Moegi Komura, Tadashi Sato, Hitomi Yoshikawa, Naoko Arano Nitta, Yohei Suzuki, Kengo Koike, Yuzo Kodama, Kuniaki Seyama, Kazuhisa Takahashi
- Organizer
  第63回日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-20K08575
[Presentation] 加熱式タバコIQOSの慢性曝露はマウス肺にアポトーシスと肺気腫を誘導し、そのエアロゾルに含まれるプロピレングリコール曝露がその一因となる2023
- Author(s)
  小村萌起、佐藤匡、西沖俊彦、堀越　公子、吉川仁美、新田（荒野）直子、鈴木洋平、小池建吾、児玉裕三、瀬山邦明、高橋和久
- Organizer
  第116回呼吸生理フォーラム／第96回閉塞性肺疾患研究会
- Data Source
  KAKENHI-PROJECT-20K08575
[Presentation] Exposure to the Heated Tobacco Product IQOS Generates Apoptosis-Mediated Pulmonary Emphysema in Mice Lungs2021
- Author(s)
  Naoko Nitta, Tadashi Sato, Moegi Komura, Hitomi Yoshikawa, Yohei Suzuki, Aki Mitsui, Eriko Kuwasaki, Fumiyuki Takahashi, Yuzo Kodama, Kuniaki Seyama, Kazuhisa Takahashi.
- Organizer
  American Thoracic Society　International　Conference 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08575
[Presentation] Exposure to the heated tobacco product IQOS generates apoptosis-mediated pulmonary emphysema in murine lungs2021
- Author(s)
  Naoko Arano Nitta, Tadashi Sato, Moegi Komura, Hitomi Yoshikawa, Yohei Suzuki, Aki Mitsui, Eriko Kuwasaki, Fumiyuki Takahashi, Yuzo Kodama, Kuniaki Seyama, Kazuhisa Takahashi
- Organizer
  The 25th Congress of the Asian Pacific Society of Respirology: APSR 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08575
[Presentation] Propylene glycol and glycerol, components of e-cigarettes and heated tobacco products, damage epithelial cells in human airways2021
- Author(s)
  Moegi Komura, Tadashi Sato, Naoko Arano Nitta, Hitomi Yoshikawa, Yohei Suzuki, Yuzo Kodama, Kuniaki Seyama, Kazuhisa Takahashi.
- Organizer
  The 25th Congress of the Asian Pacific Society of Respirology: APSR 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08575
[Presentation] シンポジウム「難病診療の現況」　リンパ脈管筋腫症2019
- Author(s)
  瀬山邦明
- Organizer
  第59回日本呼吸器学会学術講演会
- Invited
- Data Source
  KAKENHI-PROJECT-16K09589
[Presentation] Hydrogen-rich pure water prevents cigarette smoke-induced pulmonary emphysema in SMP30 knockout mice2018
- Author(s)
  Yohei Suzuki, Tadashi Sato, Masataka Sugimoto, Hario Baskoro, Keiko Karasutani, Aki Mitsui, Fariz Nurwidya, Naoko Arano, Yuzo Kodama, Shin-ichi Hirano, Akihito Ishigami, Kuniaki Seyama, Kazuhisa Takahashi
- Organizer
  第58回日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-17K09668
[Presentation] 水素分子が慢性タバコ煙曝露によるマウス肺組織傷害に与える影響2017
- Author(s)
  鈴木洋平、佐藤匡、杉本昌隆、Hario Baskoro、烏谷恵子、三井亜樹、荒野直子、児玉裕三、佐藤文平、平野伸一、黒川亮介、石神昭人、瀬山邦明、高橋和久
- Organizer
  第7回日本分子状水素医学生物学会大会
- Data Source
  KAKENHI-PROJECT-17K09668
[Presentation] Hydrogen-rich pure water prevents cigarette smoke-induced pulmonary emphysema in SMP30 knockout mice2017
- Author(s)
  Yohei Suzuki, Tadashi Sato, Masataka Sugimoto, Hario Baskoro, Keiko Karasutani, Aki Mitsui, Yuzo Kodama, Mitsuaki Sekiya, Akihito Ishigami, Kuniaki Seyama, Kazuhisa Takahashi
- Organizer
  American Thoracic Society　International　Conference 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09668
[Presentation] Hydrogen-rich pure water prevents cigarette smoke-induced pulmonary emphysema in SMP30 knockout mice2017
- Author(s)
  Yohei Suzuki, Tadashi Sato, Masataka Sugimoto, Hario Baskoro, Keiko Karasutani, Aki Mitsui, Yuzo Kodama, Mitsuaki Sekiya, Akihito Ishigami, Kuniaki Seyama, Kazuhisa Takahashi
- Organizer
  American Thoracic Society　International　Conference 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461199
[Presentation] 末梢気道と中枢気道におけるタバコ煙曝露に対する反応性の違い2017
- Author(s)
  佐藤匡、Hario Baskoro、荒野直子、鈴木洋平、烏谷惠子、三井亜樹、児玉裕三、瀬山邦明、高橋和久
- Organizer
  第91回閉塞性肺疾患研究会
- Data Source
  KAKENHI-PROJECT-17K09668
[Presentation] Regional heterogeneity of airway epithelial cells in response to cigarette smoke extract2017
- Author(s)
  Hario Baskoro, Tadashi Sato, Keiko Karasutani, Yohei Suzuki, Naoko Arano, Moegi Komura, Mitsuaki Sekiya, Yuzo Kodama, Kuniaki Seyama, Kazuhisa Takahashi
- Organizer
  第57回日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-26461199
[Presentation] COPDモデルマウスを用いたビタミンC治療による肺胞修復メカニズムの遺伝子学的解析2017
- Author(s)
  荒野直子、佐藤匡、烏谷惠子、Hario Baskoro、鈴木洋平、三井亜樹、児玉裕三、近藤嘉高、石神昭人、瀬山邦明、高橋和久
- Organizer
  第57回日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-17K09668
[Presentation] COPDモデルマウスを用いたビタミンC治療による肺胞修復メカニズムの遺伝子学的解析2017
- Author(s)
  荒野直子、佐藤匡、烏谷惠子、Hario Baskoro、鈴木洋平、三井亜樹、児玉裕三、近藤嘉高、石神昭人、瀬山邦明、高橋和久
- Organizer
  第57回日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-26461199
[Presentation] Regional heterogeneity of airway epithelial cells in response to cigarette smoke extract2017
- Author(s)
  Hario Baskoro, Tadashi Sato, Keiko Karasutani, Yohei Suzuki, Naoko Arano, Moegi Komura, Mitsuaki Sekiya, Yuzo Kodama, Kuniaki Seyama, Kazuhisa Takahashi
- Organizer
  第57回日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-17K09668
[Presentation] COPD急性増悪におけるmicroRNA-146aの役割の解明2016
- Author(s)
  烏谷惠子、佐藤匡、Hario Baskoro、鈴木洋平、関谷充晃、児玉裕三、瀬山邦明、高橋和久
- Organizer
  第56回日本呼吸器学会学術講演会
- Place of Presentation
  京都
- Year and Date
  2016-04-08
- Data Source
  KAKENHI-PROJECT-26461199
[Presentation] MiR-146a plays a pathogenetic role in the abnormal inflammatory lung response of the chronic obstructive pulmonary disease model mice2015
- Author(s)
  Tadashi Sato, Hario Baskoro, Aki Mitsui, Motoyasu Kato, Yohei Suzuki, Keiko Karasutani, Mitsuaki Sekiya, Yuzo Kodama, Fumiyuki Takahashi, Kuniaki Seyama, Kazuhisa Takahashi
- Organizer
  American Thoracic Society　International　Conference 2015
- Place of Presentation
  Denver (USA)
- Year and Date
  2015-05-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461199
[Presentation] 遺伝性呼吸器疾患の疾患特異的iPS細胞樹立2015
- Author(s)
  後藤慎平、伊藤功朗、興梠陽平、山本佑樹、小西聡史、長崎忠雄、松本久子、佐藤篤靖、室繁郎、平井豊博、長船健二、浅香勲、瀬山邦明、三嶋理晃
- Organizer
  第55回日本呼吸器学会
- Place of Presentation
  東京国際フォーラム
- Year and Date
  2015-04-17
- Data Source
  KAKENHI-PROJECT-15H02537
[Presentation] Birt-Hogg-Dube Syndromeによる気胸と原発性自然気胸の臨床的特徴の検討2015
- Author(s)
  江花弘基, 安藤克利, 溝渕輝明, 栗原正利, 瀬山邦明, 高橋和久
- Organizer
  日本呼吸器学会
- Place of Presentation
  東京
- Year and Date
  2015-04-17
- Data Source
  KAKENHI-PROJECT-25670402
[Presentation] 肺病変でBirt-Hogg-Dube症候群が疑われた31例における皮膚病変と病理学的検討2015
- Author(s)
  岩渕千雅子, 根岸亜津佐, 江花弘基, 溝渕輝明, 熊坂利夫, 瀬山邦明, 栗原正利
- Organizer
  日本気胸・嚢胞性肺疾患学会
- Place of Presentation
  東京
- Year and Date
  2015-09-04
- Data Source
  KAKENHI-PROJECT-25670402
[Presentation] Birt-Hogg-Dube Syndromeを考慮すべき臨床指標の検討2015
- Author(s)
  江花弘基, 溝渕輝明, 星加義人, 小林悦子, 熊坂利夫, 安藤克利, 芳賀高浩, 福岡みずき, 高橋和久, 瀬山邦明, 栗原正利
- Organizer
  日本気胸・嚢胞性肺疾患学会
- Place of Presentation
  東京
- Year and Date
  2015-09-04
- Data Source
  KAKENHI-PROJECT-25670402
[Presentation] Birt-Hogg-Dube症候群に対する胸膜カバーリング術の範囲と気胸再発率に関する検討2015
- Author(s)
  溝渕輝明, 江花弘基, 肥塚智, 高橋亮, 瀬山邦明, 栗原正利
- Organizer
  日本気胸・嚢胞性肺疾患学会
- Place of Presentation
  東京
- Year and Date
  2015-09-04
- Data Source
  KAKENHI-PROJECT-25670402
[Presentation] ヒト多能性幹細胞から呼吸器上皮細胞への分化誘導2015
- Author(s)
  後藤慎平、伊藤功朗、興梠陽平、山本佑樹、小西聡史、長崎忠雄、松本久子、佐藤篤靖、室繁郎、平井豊博、長船健二、浅香勲、瀬山邦明、三嶋理晃
- Organizer
  第15回　日本細胞生物学会
- Place of Presentation
  タワーホール船堀
- Year and Date
  2015-06-30
- Data Source
  KAKENHI-PROJECT-15H02537
[Presentation] MiR-146a plays a pathogenetic role in the abnormal inflammatory response in the lungs of a murine COPD model2015
- Author(s)
  Hario Baskoro, Tadashi Sato, Motoyasu Kato, Yohei Suzuki, Keiko Karasutani, Mitsuaki Sekiya, Yuzo Kodama, Fumiyuki Takahashi, Kuniaki Seyama, Kazuhisa Takahashi
- Organizer
  第55回日本呼吸器学会学術講演会
- Place of Presentation
  東京
- Year and Date
  2015-04-17
- Data Source
  KAKENHI-PROJECT-26461199
[Presentation] リンパ脈管筋腫症2012
- Author(s)
  瀬山邦明
- Organizer
  第52回日本呼吸器学会教育講演
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-21659210
[Presentation] Pregnancy and childbirth after the establishment of the diagnosis of lymphangioleiomyomatosis2011
- Author(s)
  Goto N, Seyama K, Yoshimoto K, Kurihara M, Kikuchi T, Kokubu F, Gunji Y, Kunogi M, Takahashi K
- Organizer
  American Thoracic Society Meeting
- Place of Presentation
  Denver
- Data Source
  KAKENHI-PROJECT-21659210
[Presentation] リンパ脈管筋腫症の展望-特定疾患認定をうけて-認定基準とその問題点2010
- Author(s)
  瀬山邦明
- Organizer
  第50回日本呼吸器学会特別報告
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-21659210
[Presentation] リンパ脈管筋腫症の展望-特定疾患認定を受けて-認定基準とその問題点2010
- Author(s)
  瀬山邦明
- Organizer
  第50回日本呼吸器学会特別報告5
- Place of Presentation
  国立京都国際会館
- Year and Date
  2010-04-25
- Data Source
  KAKENHI-PROJECT-21659210
[Presentation] 乳び体腔液中LAM cell cluster (LCC)の細胞学的特徴とその意義2008
- Author(s)
  三谷恵子, 熊坂利夫, 林大久生, 須田耕一, 山鳥一郎, 郡司陽子, 秋吉妙子, 瀬山邦明
- Organizer
  日本呼吸器学会総会
- Place of Presentation
  東京
- Year and Date
  2008-05-12
- Data Source
  KAKENHI-PROJECT-19590406
[Presentation] 乳糜胸水合併LAM症例における低用量GnRH療法の効果2008
- Author(s)
  郡司陽子, 瀬山邦明, 熊坂利夫, 三谷恵子, 佐藤輝彦, 秋吉妙子, 小池建吾, 高橋和久
- Organizer
  日本呼吸器学会総会
- Place of Presentation
  東京
- Year and Date
  2008-05-12
- Data Source
  KAKENHI-PROJECT-19590406
[Presentation] 重症リンパ脈管筋腫症における中枢気道の病理学的解析2008
- Author(s)
  熊坂利夫, 三谷恵子, 林大久生, 山鳥一郎, 瀬山邦明
- Organizer
  日本病理学会総会
- Place of Presentation
  金沢
- Year and Date
  2008-05-17
- Data Source
  KAKENHI-PROJECT-19590406
[Presentation] Lymphangiogenesis in lymphangioleiomyomatosis-Lymphangiogenesis and GnRH therapy-2008
- Author(s)
  Seyama K
- Organizer
  LAM Foundation 2008 International Research Conference
- Place of Presentation
  in Cincinnati USA
- Data Source
  KAKENHI-PROJECT-18390243
[Presentation] 重症肺リンパ脈管筋腫症における中枢気道障害の病理組織学的解析2008
- Author(s)
  熊坂利夫, 三谷恵子, 林大久生, 山鳥一郎, 瀬山邦明
- Organizer
  日本病理学会総会
- Place of Presentation
  金沢市・おもてなしホール
- Year and Date
  2008-05-17
- Data Source
  KAKENHI-PROJECT-19590406
[Presentation] Lymphangiogenesis in lymphangioleiomyomatosis -Lymphangiogenesis and GnRH therapy-9:25-9:50a. m.2008
- Author(s)
  Seyama K
- Organizer
  LAM Foundation 2008 International Research Conference
- Place of Presentation
  Cincinnati, USA
- Year and Date
  2008-04-05
- Data Source
  KAKENHI-PROJECT-18390243
[Presentation] Cytological, immunocytochemical, and ultrastructual characterization of LAM cell clusters in Chylous Effusion in patients with Lymphangioleiomyomatosis2007
- Author(s)
  Mitani K, Kumasaka K, Takemura H, Hayashi T, Hosokawa Y, Suda K, Gunji Y, Akiyoshi T, Seyama K
- Organizer
  The LAM Foundation 2007 lymphangiogenesis international research conference
- Data Source
  KAKENHI-PROJECT-19590406
[Presentation] Cytological, immunocytochemical, and ultrastructual characterization of LAM cell clusters in chylous effusion in patients with lymphangioleiomyomatosis2007
- Author(s)
  Mitani K, Kumasaka T, Takemura H, Hayashi T, Hosokawa Y, Suda K, Gunji Y, Akiyoshi T, Seyama K
- Organizer
  LAM Foundation 2007 International Research Conference
- Place of Presentation
  in Cincinnati USA
- Year and Date
  2007-04-20
- Data Source
  KAKENHI-PROJECT-18390243
[Presentation] Effect of long term administration of gonadotropin-releasing hormone an alogues on chylous effusion in patients with lymphangioleiomyomatosis2007
- Author(s)
  Seyama K
- Organizer
  The LAM foundation/NHLBI International Research Conference
- Place of Presentation
  Cincinnati,USA
- Year and Date
  2007-04-21
- Data Source
  KAKENHI-PROJECT-18390243
[Presentation] Loss of Heterozygosity of the TSC Genes and Overexpression of mTOR-related Proteins in Multifocal Micronodular Pneumocyte Hyperplasia (MMPH) of the Lung2007
- Author(s)
  Hayashi T, Kumasaka T, Mitani K, Gunji Y, Suda K, Seyama K
- Organizer
  The LAM Foundation 2007 lymphangiogenesis international research conference
- Data Source
  KAKENHI-PROJECT-19590406
[Presentation] Effect of long term administration of gonadotropin-releasing hormone analogueson chylous effusion in patients with lymphangioleiomyomatosis2007
- Author(s)
  Seyama K, Sato T, Gunji Y, Kumasaka T, Mitani K, Akiyoshi T, Tobino K, Hayashi T
- Organizer
  LAM Foundation2007 International Research Conference
- Place of Presentation
  in Cincinnati USA.
- Year and Date
  2007-04-20
- Data Source
  KAKENHI-PROJECT-18390243
[Presentation] Genetic and Molecular Mechanism of Diffuse Lung Diseases 2. Lymphangioleiomyomatosis2007
- Author(s)
  Seyama K
- Organizer
  The 4th international meeting of WASOG
- Place of Presentation
  Tokyo
- Year and Date
  2007-10-20
- Data Source
  KAKENHI-PROJECT-18390243
[Presentation] Loss of heterozygosity of the TSC genes and overexpression of mTOR-related proteins in multifocalmicronodular pneumocyte hyperplasia of the lung2007
- Author(s)
  Hayashi H, Kumasaka T, Mitani K, Gunji Y, Suda K, Seyama K
- Organizer
  LAM Foundation 2007 International Research Conference
- Place of Presentation
  in Cincinnati USA
- Year and Date
  2007-04-20
- Data Source
  KAKENHI-PROJECT-18390243
[Presentation] LAM and Lymphangiogenesis2007
- Author(s)
  Seyama K
- Organizer
  Global LAM summit
- Place of Presentation
  in Stockholm
- Year and Date
  2007-02-25
- Data Source
  KAKENHI-PROJECT-18390243
[Presentation] Effect of long term administration of gonadotropin-releasing hormone analogues on chylous effusion in patients with lymphangioleiomyomatosis2007
- Author(s)
  Seyama K, Sato T, Gunji Y, Kumasaka T, Mitani K, Akiyoshi T, Tobino K, Hayashi T
- Organizer
  LAM Foundation 2007 lymphangiogenesis international research conference
- Data Source
  KAKENHI-PROJECT-19590406
[Presentation] MiR-146a plays a pathogenetic role in the abnormal inflammatory response in the lungs of a murine COPD model
- Author(s)
  Hario Baskoro, Tadashi Sato, Motoyasu Kato, Yohei Suzuki, Keiko Karasutani, Mitsuaki Sekiya, Yuzo Kodama, Fumiyuki Takahashi, Kuniaki Seyama, Kazuhisa Takahashi
- Organizer
  第55回日本呼吸器学会学術講演会
- Place of Presentation
  東京国際フォーラム（東京）
- Year and Date
  2015-04-17 – 2015-04-19
- Data Source
  KAKENHI-PROJECT-26461199
[Presentation] MiR-146a plays a pathogenetic role in the abnormal inflammatory lung response of the chronic obstructive pulmonary disease model mice
- Author(s)
  Tadashi Sato, Hario Baskoro, Aki Mitsui, Motoyasu Kato, Yohei Suzuki, Keiko Karasutani, Mitsuaki Sekiya, Yuzo Kodama, Fumiyuki Takahashi, Kuniaki Seyama, Kazuhisa Takahashi
- Organizer
  American Toracic Society International Conference 2015
- Place of Presentation
  Denver (U.S.A.)
- Year and Date
  2015-05-15 – 2015-05-20
- Data Source
  KAKENHI-PROJECT-26461199
[Presentation] miR-146a Plays Pathogenic Role in Abnormal Inflammatory Response of a Murine COPD Model
- Author(s)
  Hario Baskoro, Tadashi Sato, Aki Mitsui, Yohei Suzuki, Fumiyuki Takahashi, Motoyasu Kato, Fariz Nurwidya, Kuniaki Seyama, Kazuhisa Takahashi.
- Organizer
  The 19th Congress of the Asian Pacific Society of Respirology: APSR 2014
- Place of Presentation
  Bali (Indonesia)
- Year and Date
  2014-11-13 – 2014-11-16
- Data Source
  KAKENHI-PROJECT-26461199

1. FUKUCHI Yoshinosuke (80010156)

# of Collaborated Projects: 4 results

# of Collaborated Products: 1 results
2. Sato Tadashi (10596993)

# of Collaborated Projects: 4 results

# of Collaborated Products: 32 results
3. KUMASAKA Toshio (00286709)

# of Collaborated Projects: 3 results

# of Collaborated Products: 25 results
4. TAKAHASHI Kazuhisa (80245711)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. MISHIMA MICHIAKI (60190625)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
6. SETOGUCHI Yasuhiro (90206649)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. KODAMA Yuzo (30384069)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. HANDA Tomohiro (10432395)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. HIRAI Toyohiro (20359805)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
10. ITO Isao (40447975)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
11. MURO Shigeo (60344454)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
12. MATSUMOTO Hisako (60359809)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
13. CHIN Kazuo (90197640)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. KIKKAWA Mika (90327792)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
15. NUKIWA Toshihiro (40129036)

# of Collaborated Projects: 2 results

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16. 高橋史行 (70327823)

# of Collaborated Projects: 2 results

# of Collaborated Products: 19 results
17. OGAWA Emiko (00378671)

# of Collaborated Projects: 1 results

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18. HEIKE Toshio (90190173)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. ISHIGAMI Akihito (50270658)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
20. TAKAHASHI Satsuki (40216718)

# of Collaborated Projects: 1 results

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21. TAKAHASHI Hideki (90216747)

# of Collaborated Projects: 1 results

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22. SATO Teruhiko (10348964)

# of Collaborated Projects: 1 results

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23. IWAKAMI Shinichiro (80311984)

# of Collaborated Projects: 1 results

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24. 星野勇馬 (00378746)

# of Collaborated Projects: 1 results

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25. 新実彰男 (30252513)

# of Collaborated Projects: 1 results

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26. 岡正彦 (60203965)

# of Collaborated Projects: 1 results

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27. 金永学 (20456883)

# of Collaborated Projects: 1 results

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28. 佐藤篤靖 (30706677)

# of Collaborated Projects: 1 results

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29. 佐藤晋 (40378691)

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31. 堀田秋津 (50578002)

# of Collaborated Projects: 1 results

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32. 小熊毅 (50601324)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. 後藤慎平 (50747219)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
34. 小笹裕晃 (80572015)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. 永井宏樹 (80711605)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
36. 浅香勲 (10543639)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
37. 谷澤公伸 (20639140)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
38. 田島健 (50384102)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
39. 荒谷紗絵 (60844131)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
40. 光石陽一郎 (10647001)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
41. 新井田要 (40293344)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
42. SUZUKI Yohei

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
43. MITSUI Aki

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
44. 林大久生

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
45. 三谷恵子

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
46. RENNARD Stephen I.

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
47. SUGIMOTO Masataka

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
48. SUGIMOTO Kazushi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

seyama kuniaki 瀬山 邦明

SEYAMA Kuniaki 瀬山 邦明

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リンパ脈管筋腫症は神経堤由来間葉系幹細胞が分化制御異常を来した疾患であるPrincipal Investigator

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The role of extracellular vesicles in the pathobiology of lymphangioleiomyomatosisPrincipal Investigator

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Investigation on the endothelial-mesenchymal transition in lymphangioleiomyomatosisPrincipal Investigator

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To develop a novel method to establish the diagnosis of BHD syndromePrincipal Investigator

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Isolation of LAM stem cells and its application for the establishment of mouse LAM model.Principal Investigator

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seyama kuniaki 瀬山邦明

SEYAMA Kuniaki 瀬山邦明