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Ohyama Manabu  大山 学

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… Alternative Names

大山 学  オオヤマ マナブ

OHYAMA Manabu  大山 学

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Researcher Number 10255424
Other IDs
Affiliation (Current) 2025: 杏林大学, 医学部, 教授
Affiliation (based on the past Project Information) *help 2025: 杏林大学, 医学部, 教授
2022 – 2023: 杏林大学, 医学部, 教授
2015 – 2019: 杏林大学, 医学部, 教授
2014: 慶應義塾大学, 医学部, 准教授
2010 – 2013: 慶應義塾大学, 医学部, 講師 … More
2008 – 2010: 慶応義塾大学, 医学研究科, 講師
2007 – 2008: Keio University, 医学部, 講師
2006: 慶應義塾大学, 医学部, 助手
1999 – 2001: 慶應義塾大学, 医学部, 助手
2000: 慶應大, 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
Dermatology / Basic Section 53050:Dermatology-related / Dermatology
Except Principal Investigator
Dermatology / Dermatology / Veterinary medical science / Clinical veterinary science
Keywords
Principal Investigator
毛包 / 分化誘導 / ヒトiPS細胞 / 付属器 / 再生医学 / 疾患モデル / ヒト培養皮膚 / 皮膚疾患 / 組織再生 / 汗腺 … More / 立体培養 / 皮膚付属器 / iPS細胞 / 発生・分化 / ヒト付属器再生 / 皮膚再生学 / 付属器再生 / ヒト皮膚再生 / スクリーニング / 共培養 / 細胞・組織 / ヒト毛包再生 / 上皮―間葉系相互作用 / 上皮ー間葉系相互作用 / 毛包再生 / 幹細胞 / 組織再構成 / 毛乳頭 / バルジ / 皮膚幹細胞 / 毛嚢 / 皮膚生理学 … More
Except Principal Investigator
自己免疫 / Model mouse / Autoimmune / ノックアウトマウス / モデルマウス / 創傷治癒 / 毛包 / 幹細胞 / 天疱瘡 / 自己抗体 / WNTシグナル / FGF / 毛乳頭細胞 / 線維芽細胞 / 毛包新生 / 毛包再生 / desmoglein / pemphigus / knockout mouse / bullous disease / epitope / Autoantibody / デスモグレイン / 水疱症 / エピトープ / CD40 ligand / Skin graft / Knockout mouse / Immune response / Inherited disease / Gene therapy / 経鼻免疫 / 経口免疫 / 免疫寛容 / 遺伝性皮膚疾患 / CD40リガンド / 皮膚移植 / 免疫宣容 / 遺伝皮膚疾患 / 遺伝子治療 / 神経堤細胞 / 皮膚腫瘍 / コンディショナルノックアウトマウス / ネスチン / 経皮免疫 / 抗原感作 / 皮膚バリア解析 / 角質 / アトピー性皮膚炎 / タイトジャンクション / 皮膚バリア機構 / ランゲルハンス細胞 / 角質バリア / タイトジャンクションバリア / 皮膚バリア / 皮膚 / 犬 / 重症度 / BIAcore / バイオセンサー / 反応速度 / 自己抗原 Less
  • Research Projects

    (14 results)
  • Research Products

    (87 results)
  • Co-Researchers

    (20 People)
  •  ヒト毛包再生モデルを用いたJAK阻害薬が毛包に与える直接的影響の検討Principal Investigator

    • Principal Investigator
      大山 学
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53050:Dermatology-related
    • Research Institution
      Kyorin University
  •  Attempt to reproduce pathophysiology of skin diseases by use of human three-dimensional skin equivalent with regenerated skin appendage structuresPrincipal Investigator

    • Principal Investigator
      大山 学
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53050:Dermatology-related
    • Research Institution
      Kyorin University
  •  Attempt to regenerate skin appendages using reconstituted embryonal-like skin equivalent using human induced pluripotent stem cellsPrincipal Investigator

    • Principal Investigator
      Ohyama Manabu
    • Project Period (FY)
      2016 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Dermatology
    • Research Institution
      Kyorin University
  •  Attempt to establish screening system for drug to treat alopecia using human iPS cellsPrincipal Investigator

    • Principal Investigator
      Manabu Ohyama
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Dermatology
    • Research Institution
      Kyorin University
  •  Development of folliclogenetic tecnique utilizing mesenchymal cells capable of controlling microenvironment

    • Principal Investigator
      Kinoshita Misaki
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Dermatology
    • Research Institution
      Kyorin University
  •  Attempt to regenerate hair follicles using human iPS cell-derived epithelial and mesenchymal cells optimized for trichogenicityPrincipal Investigator

    • Principal Investigator
      Ohyama Manabu
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Dermatology
    • Research Institution
      Kyorin University
      Keio University
  •  Investigation of unknown transdifferentiation mechanisms of cutaneous epithelial tumor and related genes

    • Principal Investigator
      NISHIFUJI Koji
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Veterinary medical science
    • Research Institution
      Tokyo University of Agriculture and Technology
  •  Analysis of the dynamic skin immune and physical barrier system by tight junctions and Langerhans cells

    • Principal Investigator
      KUBO Akiharu
    • Project Period (FY)
      2010 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Dermatology
    • Research Institution
      Keio University
  •  Identification of canine hair follicle stem cells, reconstruction Of hair follicle and its application to wound healing

    • Principal Investigator
      IWASAKI Toshiroh
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Clinical veterinary science
    • Research Institution
      Tokyo University of Agriculture and Technology
  •  Experimental regeneration of human hair follicles using CD200 positive bulge cellsPrincipal Investigator

    • Principal Investigator
      OHYAMA Manabu
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Dermatology
    • Research Institution
      Keio University
  •  天疱瘡自己抗体の3次元エピトープの解析Principal Investigator

    • Principal Investigator
      大山 学
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Dermatology
    • Research Institution
      Keio University
  •  Basic studies for development of disease-specific therapeutic strategies against autoimmune diseases

    • Principal Investigator
      NISHIKAWA Takeji
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Dermatology
    • Research Institution
      Keio University
  •  抗原抗体反応速度論的解析による自己抗体病原性強度の新しい指標の開発

    • Principal Investigator
      MASAYUKI Amagai
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Dermatology
    • Research Institution
      Keio University
  •  Development of immune supression against gene product in gene therapy

    • Principal Investigator
      AMAGAI Masayuki
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Dermatology
    • Research Institution
      Keio University

All 2024 2020 2019 2018 2017 2016 2015 2014 2012 2011 2010 2009 2008 2007 Other

All Journal Article Presentation Book Patent

  • [Book] Springer Series Advances in Stem Cell Biology “Induced Pluripotent Stem Cells; Novel Concepts” Chapter: Strategies to utilize iPS cells for hair follicle regeneration and the treatment of hair loss disorders2020

    • Author(s)
      Manabu Ohyama (Alex Birbrair ed.)
    • Publisher
      Elsevier (San Diego)
    • ISBN
      9780128222287
    • Data Source
      KAKENHI-PROJECT-16H05370
  • [Book] 毛髪科学の新展開(第5章:脱毛症の病態から考える毛包再生医療の適応と課題)2019

    • Author(s)
      大山 学 (監修:岩渕徳郎)
    • Total Pages
      283
    • Publisher
      シーエムシー出版
    • ISBN
      9784781314341
    • Data Source
      KAKENHI-PROJECT-16H05370
  • [Journal Article] Increase in CD8+ Effector Memory T Cells Re-Expressing CD45RA Correlates with Intractability of Severe Alopecia Areata2024

    • Author(s)
      Ryo Takahashi, Misaki Kinoshita-Ise, Yoshimi Yamazaki, Masahiro Fukuyama, Manabu Ohyama
    • Journal Title

      Journal of Investigative Dermatology

      Volume: S0022-202X(24)00025-3 Issue: 7 Pages: 1654-1657.e7

    • DOI

      10.1016/j.jid.2024.01.006

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K08438, KAKENHI-PROJECT-20K17328
  • [Journal Article] Use of human intra-tissue stem/progenitor cells and induced pluripotent stem cells for hair follicle regeneration2019

    • Author(s)
      Ohyama Manabu
    • Journal Title

      Inflammation and Regeneration

      Volume: 39 Issue: 1 Pages: 4-4

    • DOI

      10.1186/s41232-019-0093-1

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H05370
  • [Journal Article] Induction of hair follicle dermal papilla cell properties in human induced pluripotent stem cell-derived multipotent LNGFR(+)THY-1(+) mesenchymal cells2017

    • Author(s)
      Ophelia Veraitch, Yo Mabuchi, Yumi Matsuzaki, Takashi Sasaki, Hironobu Okuno, Aki Tsukashima, Masayuki Amagai, Hideyuki Okano, Manabu Ohyama
    • Journal Title

      Scientific Reports

      Volume: 21 Issue: 1 Pages: 42777-42777

    • DOI

      10.1038/srep42777

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K15421, KAKENHI-PROJECT-15K06853
  • [Journal Article] LNGFR+THY-1+ Human Pluripotent Stem Cell-derived Neural Crest-Like Cells Have the Potential to Develop Into Mesenchymal Stem Cells2016

    • Author(s)
      Takehito Ouchi, Satoru Morikawa, Shinsuke Shibata, Kimiko Fukuda, Hironobu Okuno, Takumi Fujimura, Tatsuo Kuroda, Manabu Ohyama, Wado Akamatsu, Taneaki Nakagawa, Hideyuki Okano
    • Journal Title

      Differentiation

      Volume: 印刷中

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25293246
  • [Journal Article] iPS細胞の毛包への誘導2015

    • Author(s)
      大山 学
    • Journal Title

      日本臨牀増刊号「再生医療」

      Volume: 73 Pages: 193-198

    • Data Source
      KAKENHI-PROJECT-25293246
  • [Journal Article] Promise of human induced pluripotent stem cells in skin regeneration and investigation.2014

    • Author(s)
      Ohyama M, Okano H
    • Journal Title

      J Invest Dermatol

      Volume: 134 Issue: 3 Pages: 605-609

    • DOI

      10.1038/jid.2013.376

    • Data Source
      KAKENHI-PROJECT-25293246
  • [Journal Article] Stress-induced production of chemokines by hair follicles regulates the trafficking of dendritic cells in skin.2012

    • Author(s)
      Keisuke Nagao
    • Journal Title

      Nature Immunology

      Volume: 13(8) Issue: 8 Pages: 744-752

    • DOI

      10.1038/ni.2353

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12J08120, KAKENHI-PROJECT-21229014, KAKENHI-PROJECT-22249044, KAKENHI-PROJECT-22390095, KAKENHI-PROJECT-23790432, KAKENHI-PROJECT-24659216, KAKENHI-PROJECT-24659373, KAKENHI-PUBLICLY-23118526
  • [Journal Article] Molecular biological and immunohistopathological characterization of canine dermal papilla cells and the evaluation of cutaneous conditions2011

    • Author(s)
      Kobayashi T, Iwasaki T, Ohyama T, et al.
    • Journal Title

      Veterinary Dermatology

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20380171
  • [Journal Article] Molecular biological and immunohistological characterization of canine dermal papilla cells and the evaluation of cutaneous conditions.2011

    • Author(s)
      Kobayashi T, Fujisawa A, Amagai A, Iwasaki T, Ohyama M
    • Journal Title

      Veterinary Dermatology in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20380171
  • [Journal Article] Canine follicle stem cell candidates reside in the bulge and share characteristic features with human bulge cells.2010

    • Author(s)
      Kobayashi T, Iwasaki T, Amagai M, Ohyama M
    • Journal Title

      Journal of Investigative Dermatology 130

      Pages: 1988-1995

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20380171
  • [Journal Article] Canine follicle stem cell candidates reside in the bulge and share chars cteristic features with human bulge cells2010

    • Author(s)
      Kobayashi T, Iwasaki T, Ohyama, et al.
    • Journal Title

      Journal of Investigative Dermatology

      Volume: 130 Pages: 1988-1995

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20380171
  • [Journal Article] Canine hair-follicle keratinocytes enriched with bulge cells have the highly proliferative characteristic of stem cells.2009

    • Author(s)
      Kobayashi T, Shimizu A, Nishifuji K, Amagai M, Iwasaki T, Ohyama M
    • Journal Title

      Veterinary Dermatology 20

      Pages: 338-346

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20380171
  • [Journal Article] Sparing of the bulge area could preserve intact lower portion of hair follicles in a case of tufted folliculitis2009

    • Author(s)
      Miura M, Dekio I, Yamasaki Y, Ohyama M
    • Journal Title

      J Eur Acad Dermatol Venereol 23

      Pages: 87-89

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390315
  • [Journal Article] Sparing of the bulge area could preserve intact lower portion of hair follicles in a case of tufted folliculitis2009

    • Author(s)
      Miura M, Dekio I, Yamasaki Y, Ohyama M.
    • Journal Title

      J Eur Acad Dermatol Venereol 23(1)

      Pages: 87-89

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390315
  • [Journal Article] 皮膚幹細胞の新知見2009

    • Author(s)
      大山 学
    • Journal Title

      日本皮膚科学会雑誌 (印刷中)

    • NAID

      10028279218

    • Data Source
      KAKENHI-PROJECT-18390315
  • [Journal Article] 毛包幹細胞・毛包再生の最前線2008

    • Author(s)
      大山 学
    • Journal Title

      Monthly Book Derma 145

      Pages: 7-13

    • Data Source
      KAKENHI-PROJECT-18390315
  • [Journal Article] Gene ontology analysis of human hair follicle bulge molecular signature2007

    • Author(s)
      Ohyama M, Vogel JC, Amagai M.
    • Journal Title

      J Dermatol Sci 45

      Pages: 147-150

    • NAID

      10024115400

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390315
  • [Journal Article] ヒト毛嚢再生に向けてのアプローチ2007

    • Author(s)
      大山 学
    • Journal Title

      医学のあゆみ 223(11,12)

      Pages: 922-923

    • Data Source
      KAKENHI-PROJECT-18390315
  • [Journal Article] Advances in the study of stem-cell-enriched hair follicle bulge cells: A review featuring characterization and isolation of human bulge cells.2007

    • Author(s)
      Ohyama M
    • Journal Title

      Dermaotlogy 214(4)

      Pages: 342-351

    • Data Source
      KAKENHI-PROJECT-18390315
  • [Journal Article] Advances in the study of stem-cell-enriched hair follicle bulge cells : A review featuring characterization and isolation of human bulge cells2007

    • Author(s)
      Ohyama M
    • Journal Title

      Dermaotlogy 214(4)

      Pages: 342-351

    • Data Source
      KAKENHI-PROJECT-18390315
  • [Journal Article] Gene ontology analysis of human hair follicle bulge molecular signature.2007

    • Author(s)
      Ohyama M, Vogel JC, Amagai M
    • Journal Title

      Journal of Dermatological Science 45(2)

      Pages: 147-150

    • NAID

      10024115400

    • Data Source
      KAKENHI-PROJECT-18390315
  • [Journal Article] 12007

    • Author(s)
      大山 学
    • Journal Title

      日本皮膚科学会雑誌 117(13)

      Pages: 2415-2417

    • Data Source
      KAKENHI-PROJECT-18390315
  • [Journal Article] Hair follicle bulge : A fascinating reservoir of epithelial stem cells2007

    • Author(s)
      Ohyama M
    • Journal Title

      J Dermatol Sci 46(2)

      Pages: 81-89

    • NAID

      10024115945

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390315
  • [Journal Article] The disruption of Sox21-mediated hair shaft cuticle differentiation causes cyclic alopecia in mice

    • Author(s)
      Kiso T, Tanaka S, Saba R, Matsuda S, Shimizu A, Ohyama M, Okano HJ, Shirotori T, Okano H, Saga Y.
    • Journal Title

      Proc Natl Acad Sci USA (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390315
  • [Journal Article] The Mesenchymal component of hair follicle neogenesis : Background, methods and molecular characterization

    • Author(s)
      Ohyama M, Zheng Y, Paus R, Stenn, KS
    • Journal Title

      Exp Dermatol (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390315
  • [Journal Article] Hair follicle bulge : A fascinating reservoir of epithelial stem cells.

    • Author(s)
      Ohyama M
    • Journal Title

      Journal of Dermatological Science In press

    • NAID

      10024115945

    • Data Source
      KAKENHI-PROJECT-18390315
  • [Patent] 特許権2008

    • Inventor(s)
      大山 学, 天谷雅行
    • Industrial Property Rights Holder
      慶應義塾
    • Filing Date
      2008-08-22
    • Data Source
      KAKENHI-PROJECT-18390315
  • [Patent] 特許権2008

    • Inventor(s)
      大山学、天谷雅行
    • Industrial Property Rights Holder
      学校法人慶應義塾
    • Filing Date
      2008-08-22
    • Data Source
      KAKENHI-PROJECT-18390315
  • [Presentation] WNT・FGFシグナル活性化因子と3次元細胞凝集を用いたヒト毛乳頭細胞の特性維持法確立の試み2024

    • Author(s)
      大山 学、早川怜那、塚島明希、山﨑好美、君嶋桃子、福山雅大
    • Organizer
      第23回日本再生医療学会
    • Data Source
      KAKENHI-PROJECT-22K08438
  • [Presentation] 皮膚・付属器再生におけるiPS細胞の有用性についてー組織幹細胞・前駆細胞との比較を含めて2020

    • Author(s)
      大山 学
    • Organizer
      第19回日本再生医療学会(本来3/12-14開催を延期5/18-29Web開催)
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H05370
  • [Presentation] ヒトiPS細胞由来毛乳頭様構造体を用いたin vitroヒト毛包構造再生の試み2020

    • Author(s)
      福山雅大、塚島明希、君嶋桃子、山﨑好美、岡野栄之、大山 学
    • Organizer
      第19回日本再生医療学会(本来3/12-14開催を延期5/18-29Web開催)
    • Data Source
      KAKENHI-PROJECT-16H05370
  • [Presentation] Attempts to regenerate human hair follicle structure in vitro by three-dimentionally assembling tissue- and iPS cell-derived cell composites.2019

    • Author(s)
      Fukuyama M, Tsukashima A, Kimishima M, Yamazaki Y, Ohyama M.
    • Organizer
      The 44th Annual Meeting of the Japanese Society for Investigative Dermatology
    • Data Source
      KAKENHI-PROJECT-16H05370
  • [Presentation] ヒト3次元培養皮膚を用いた毛器官発生シグナル因子が上皮ー間葉系相互作用に与える影響の検討2019

    • Author(s)
      福山雅大、塚島明希、君嶋桃子、山崎好美、大山 学
    • Organizer
      第18回日本再生医療学会総会
    • Data Source
      KAKENHI-PROJECT-16H05370
  • [Presentation] 幹細胞・前駆細胞を用いたヒト毛包再生戦略2019

    • Author(s)
      大山 学
    • Organizer
      第118回日本皮膚科学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H05370
  • [Presentation] 毛包幹細胞の基礎と臨床2018

    • Author(s)
      大山 学
    • Organizer
      第117回日本皮膚科学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H05370
  • [Presentation] 皮膚・付属器の幹細胞と再生の現状2018

    • Author(s)
      大山 学
    • Organizer
      第39回日本炎症・再生医学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H05370
  • [Presentation] 安定した3次元培養皮膚作成のためのフィーダーフリー培養ヒトiPS細胞由来細胞調整法の検討2018

    • Author(s)
      福山雅大、塚島明希、君嶋桃子、山﨑好美、大山 学
    • Organizer
      第17回日本再生医療学会総会
    • Data Source
      KAKENHI-PROJECT-16H05370
  • [Presentation] Human scalp-derived fibroblasts alter FGF expression profile upon WNT activation: implication of their role to provide folliculogenetic microenvironment2017

    • Author(s)
      Misaki Kinoshita-Ise, Aki Tsukashima, Tomonari Kinoshita, Yoshimi Yamazaki, Manabu Ohyama
    • Organizer
      76th SID annual meeting
    • Place of Presentation
      Portland (USA)
    • Year and Date
      2017-04-26
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K19703
  • [Presentation] ヒト毛包再生に向けた上皮ー間葉系相互作用を可能にする細胞の作成-Dermal papilla細胞を中心に-2017

    • Author(s)
      大山 学
    • Organizer
      第38回日本炎症・再生医学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H05370
  • [Presentation] Attempt to establish a hair follicile co-culture model using feeder-free human iPS cells2017

    • Author(s)
      Manabu Ohyama, Aki Tsukashima, Momoko Kimishima, Yoshimi Yamazaki, Hideyuki Okano
    • Organizer
      The 27th Annual Meeting of the Korean Society for Investigative Dermatology
    • Place of Presentation
      韓国、ソウル
    • Year and Date
      2017-03-24
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K15421
  • [Presentation] ヒト線維芽細胞におけるWNTシグナル活性化時のFGF発現プロファイル変化とその毛包再生促進効果の検討2017

    • Author(s)
      木下 美咲、塚島 明希、木下 智成、山崎 好美、大山 学
    • Organizer
      第16回日本再生医療学会
    • Place of Presentation
      仙台国際センター(宮城県・仙台市)
    • Year and Date
      2017-03-09
    • Data Source
      KAKENHI-PROJECT-15K19703
  • [Presentation] ヒトiPS細胞を用いた毛包再生の試み2016

    • Author(s)
      大山 学
    • Organizer
      第79回日本皮膚科学会東京・東部支部合同学術大会
    • Place of Presentation
      東京
    • Year and Date
      2016-02-20
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K15421
  • [Presentation] Current strategy of using stem/ progenitor cells for the treatment of hair diseases2016

    • Author(s)
      Manabu Ohyama
    • Organizer
      18th Hamchun Dermatology Symposium
    • Place of Presentation
      ソウル、韓国
    • Year and Date
      2016-06-11
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05370
  • [Presentation] ヒトiPS細胞を用いた毛包再生の試み2016

    • Author(s)
      大山 学
    • Organizer
      第79回日本皮膚科学会東京・東部支部合同学術大会
    • Place of Presentation
      東京
    • Year and Date
      2016-02-20
    • Invited
    • Data Source
      KAKENHI-PROJECT-25293246
  • [Presentation] Current strategy to enhance epithelial-mesenchymal interactions for human hair follicle bioengineering2015

    • Author(s)
      Manabu Ohyama
    • Organizer
      World Congress of Dermatology 2015
    • Place of Presentation
      バンクーバー、カナダ
    • Year and Date
      2015-06-09
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25293246
  • [Presentation] Recent progress on hair bioengineering2015

    • Author(s)
      Manabu Ohyama
    • Organizer
      World Congress of Dermatology 2015
    • Place of Presentation
      バンクーバー、カナダ
    • Year and Date
      2015-06-10
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25293246
  • [Presentation] Cunrrent strategies for human hair follicle regeneration using stem or progenitor cells2015

    • Author(s)
      Manabu Ohyama
    • Organizer
      World Congress of Dermatology 2015
    • Place of Presentation
      バンクーバー、カナダ
    • Year and Date
      2015-06-09
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K15421
  • [Presentation] Investigation of the tight junction barrier in hair follicles and sebaceous glands2011

    • Author(s)
      Kubo A, Yokouchi M, Atsugi T, Ohyama M, Amagai M
    • Organizer
      The 36th Annual Meeting of the Japanese Society for Investigative Dermatology
    • Place of Presentation
      Kyoto
    • Data Source
      KAKENHI-PROJECT-22249044
  • [Presentation] Human epidermal tight junctions are functional and allow penetration of activated Langerhans cell dendrites2011

    • Author(s)
      Yoshida K, Kubo A, Yokouchi M, Ishii K, Kawasaki H, Ebihara T, Ohyama M, Nagao K, Amagai M
    • Organizer
      71th Annual Meeting Society for Investigative Dermatology
    • Place of Presentation
      Phoenix, Arizona
    • Year and Date
      2011-05-05
    • Data Source
      KAKENHI-PROJECT-22249044
  • [Presentation] Recent advances in canine hair follicle stem cell biology2011

    • Author(s)
      小林哲郎, 岩崎利郎, 大山学
    • Organizer
      2011 Annual Meeting of Australian College of Veterinary Sciences.
    • Place of Presentation
      Gold Coast, Australia
    • Data Source
      KAKENHI-PROJECT-20380171
  • [Presentation] 犬の毛包幹細胞の同定および生物学的特徴の解析2010

    • Author(s)
      小林哲郎、西藤公司、天谷雅之、岩崎利郎、大山学
    • Organizer
      第149回日本獣医学会学術集会シンポジウム:再生医療の最前線~獣医臨床応用に向けた課題
    • Place of Presentation
      東京
    • Year and Date
      2010-03-27
    • Data Source
      KAKENHI-PROJECT-20380171
  • [Presentation] Canine bulge cells share intrinsic properties with human bulge cells and provide a novel model for human hair follicles stem cell research.2010

    • Author(s)
      Kobayashi T, Iwasaki T, Amagai M, Ohyama M
    • Organizer
      6^<th> World Congress for Hair Research
    • Place of Presentation
      Cairns, Australis
    • Data Source
      KAKENHI-PROJECT-20380171
  • [Presentation] Canine bulge cells share intrinsic proterties with human bulge cells abd provide a novel model for human hair follicle stem cell research2010

    • Author(s)
      Kobayashi T, Iwasaki T, Amagai M, Ohyama M
    • Organizer
      The 6^<th> World Congress of Hair Research
    • Place of Presentation
      Cairns, Australia
    • Data Source
      KAKENHI-PROJECT-20380171
  • [Presentation] 犬の毛包幹細胞の同定と創傷治癒への応用について2010

    • Author(s)
      小林哲郎、岩崎利郎、大山学, ほか
    • Organizer
      第149回日本獣医学会
    • Place of Presentation
      日本獣医畜産大学、東京
    • Year and Date
      2010-03-27
    • Data Source
      KAKENHI-PROJECT-20380171
  • [Presentation] 新鮮分離ヒト毛乳頭の分子署名の解明-ヒト毛嚢再生に向けてのアプローチ-2009

    • Author(s)
      大山 学, 小林哲郎, 清水篤, 天谷雅行
    • Organizer
      第8回日本再生医療学会
    • Place of Presentation
      東京
    • Year and Date
      2009-03-06
    • Data Source
      KAKENHI-PROJECT-18390315
  • [Presentation] イヌの毛包幹細胞の同定および生物学的特徴の解析2009

    • Author(s)
      小林哲郎、岩崎利郎、大山学, ほか
    • Organizer
      第148回日本獣医学会
    • Place of Presentation
      とりぎん文化会館、鳥取
    • Year and Date
      2009-09-26
    • Data Source
      KAKENHI-PROJECT-20380171
  • [Presentation] An attempt to regenerate human dermal papilla with hair inductive capacity using 3D culture. system2009

    • Author(s)
      Ohyama, M
    • Organizer
      Forefront of the regenerative medicine, Symposium 2009
    • Place of Presentation
      東京
    • Year and Date
      2009-01-23
    • Data Source
      KAKENHI-PROJECT-18390315
  • [Presentation] 犬の毛包幹細胞の同定および生物学的特徴の解析2009

    • Author(s)
      小林哲郎、岩崎利郎、西藤公司、大山学
    • Organizer
      第148回日本獣医学会学術集会
    • Place of Presentation
      鳥取
    • Data Source
      KAKENHI-PROJECT-20380171
  • [Presentation] Microarray analysis of freshly-microdissected intact human dermal papilla identified upregulation of genes that could contribute to biological distinctiveness.2008

    • Author(s)
      Ohyama M, Shimizu A, Kobayashi T Amagai M
    • Organizer
      International Investigative Dermatology 2008
    • Place of Presentation
      京都
    • Year and Date
      2008-05-16
    • Data Source
      KAKENHI-PROJECT-18390315
  • [Presentation] 犬毛包はヒト毛包幹細胞研究に有用である-バルジ細胞の類似性を中心に-2008

    • Author(s)
      小林哲郎、岩崎利郎、天谷雅之、大山学
    • Organizer
      第15回毛髪科学研究会
    • Place of Presentation
      福岡
    • Year and Date
      2008-11-09
    • Data Source
      KAKENHI-PROJECT-20380171
  • [Presentation] Dissecting out molecular signatures of hair follicle key components : Implication of human hair follicle regeneration2008

    • Author(s)
      Ohyama M
    • Organizer
      Satellite Symposium on Hair Research, International Investigative Dermatology 2008
    • Place of Presentation
      京都
    • Year and Date
      2008-05-13
    • Data Source
      KAKENHI-PROJECT-18390315
  • [Presentation] 遺伝子発現プロファイルとコロニー形成能からみたヒト毛包バルジ細胞の幹細胞としての特性2008

    • Author(s)
      大山 学
    • Organizer
      第7回日本再生医療学会総会シンポジウム
    • Place of Presentation
      名古屋
    • Year and Date
      2008-03-13
    • Data Source
      KAKENHI-PROJECT-18390315
  • [Presentation] Identification and isolation of highly proliferative canine hair follicle bulge cells : promising candidate for stem cells.2008

    • Author(s)
      Kobayashi T, Nishifuji K, Iwasaki T, Amagai M, Ohyama M
    • Organizer
      The 6^<th> World Congress of Veterinary Dermatology
    • Place of Presentation
      Hong Kong
    • Data Source
      KAKENHI-PROJECT-20380171
  • [Presentation] Identification and isolation of highly proliferative canine hair follicle bulge cells, promising candidates for stem cells.2008

    • Author(s)
      Kobayashi T, Shimizu A, Nishifuji K, Amagai M, Iwasaki T Ohyama M
    • Organizer
      World Congress of Veterinary Dermatology 2008
    • Place of Presentation
      香港、中国
    • Year and Date
      2008-11-20
    • Data Source
      KAKENHI-PROJECT-18390315
  • [Presentation] 犬毛包はヒト毛包幹細胞研究に有用である-バルジ細胞の類似性を中心に-2008

    • Author(s)
      小林哲郎, 岩崎利郎, 天谷雅行, 大山学
    • Organizer
      第15回毛髪利学研究会
    • Place of Presentation
      福岡
    • Year and Date
      2008-11-29
    • Data Source
      KAKENHI-PROJECT-20380171
  • [Presentation] Identification of human bulge cell counterpart in canine hair follicles : A valuable model for stem cell investigation.2008

    • Author(s)
      Kobayashi T, Shimizu A, Amagai M, Iwasaki T, Ohyama M
    • Organizer
      International Investigative Dermatology 2008
    • Place of Presentation
      京都
    • Year and Date
      2008-05-17
    • Data Source
      KAKENHI-PROJECT-18390315
  • [Presentation] ヒト毛嚢幹細胞研究のマテリアルとしてのイヌ毛嚢の有用性の検討2008

    • Author(s)
      大山 学, 小林哲郎, 岩崎利郎, 天谷雅行
    • Organizer
      第15回分子皮膚科学フォーラム
    • Place of Presentation
      京都
    • Year and Date
      2008-11-14
    • Data Source
      KAKENHI-PROJECT-18390315
  • [Presentation] イヌ毛包はヒト毛包幹細胞研究に有用である-バルジ細胞の類似性を中心に-2008

    • Author(s)
      小林哲郎, 岩崎利郎, 天谷雅行, 大山 学
    • Organizer
      第15回毛髪科学研究会
    • Place of Presentation
      福岡
    • Year and Date
      2008-11-29
    • Data Source
      KAKENHI-PROJECT-18390315
  • [Presentation] Use of canine hair follicle epithelial hair follicle stem cells for the exploration of novel regenerative medicine approaches2008

    • Author(s)
      Ohyama, M
    • Organizer
      BCRT/BMBF Workshop, "Exploitation of hair follicle stem cells in skin defect healing"
    • Place of Presentation
      Berlin, Germany
    • Year and Date
      2008-06-19
    • Data Source
      KAKENHI-PROJECT-18390315
  • [Presentation] Identification of human bulge cell counterpart in canine hair follicles : A valuable material for stem cell investigation2008

    • Author(s)
      Kobayashi T, Iwasaki T, Nishifuji K, Amagai M, Ohyama M
    • Organizer
      International Investigative Dermatology Meeting
    • Place of Presentation
      Kyoto
    • Data Source
      KAKENHI-PROJECT-20380171
  • [Presentation] Identification of human bulge cell counterpart in canine hair follicles : A valuable model for stem cell in vesitgation2008

    • Author(s)
      Kobayashi T, Shimizu A, Amagai M, Iwasaki T, Ohyama M.
    • Organizer
      International Investigative Dermatology 2008
    • Place of Presentation
      Kyoto, Japan
    • Year and Date
      2008-05-17
    • Data Source
      KAKENHI-PROJECT-18390315
  • [Presentation] レーザーキャプチャーマイクロダイセクションを用いたヒト毛嚢バルジ細胞の分子署名の解明と細胞表面マーカーの同定2008

    • Author(s)
      大山 学
    • Organizer
      日本顕微鏡学会第52回シンポジウム
    • Place of Presentation
      千葉
    • Year and Date
      2008-10-18
    • Data Source
      KAKENHI-PROJECT-18390315
  • [Presentation] Microarray analysis of freshly-microdissected intact human dermal papilla identified upregulation of genes that could contribute to biological distinctiveness2008

    • Author(s)
      Ohyama M, Shimizu A, Kobayashi T and Amagai M.
    • Organizer
      International Investigative Deramtology 2008
    • Place of Presentation
      Kyoto Japan
    • Year and Date
      2008-05-16
    • Data Source
      KAKENHI-PROJECT-18390315
  • [Presentation] "Dissecting out molecular signatures of hair follicle key components : Implication of human hair follicle regeneration" Satellite Symposium on Hair Research2008

    • Author(s)
      Ohyama M.
    • Organizer
      International Investigative Dermatology 2008
    • Place of Presentation
      Kyoto, Japan
    • Year and Date
      2008-05-13
    • Data Source
      KAKENHI-PROJECT-18390315
  • [Presentation] Use of canine hair follicle epithelial hair follicle stem cellsfor the exploration of novel regenerative medicine approaches2008

    • Author(s)
      Ohyama M
    • Organizer
      BCRT/BMBF Workshop, “Exploitation of hair follicle stem cells in skin defect healing"
    • Place of Presentation
      ベルリン、ドイツ
    • Year and Date
      2008-06-19
    • Data Source
      KAKENHI-PROJECT-18390315
  • [Presentation] ヒト毛嚢バルジは幹細胞のニッシェである-Gene Ontoogyによるマイクロアレイデータのバイオインフォーマティックス解析-2007

    • Author(s)
      大山 学, 他2名
    • Organizer
      日本研究皮膚科学会第31回年次学術大会
    • Place of Presentation
      東京
    • Year and Date
      2007-08-03
    • Data Source
      KAKENHI-PROJECT-18390315
  • [Presentation] ケラチノサイトの幹細胞2007

    • Author(s)
      大山 学
    • Organizer
      第106回日本皮膚科学会総会
    • Place of Presentation
      横浜
    • Year and Date
      2007-04-22
    • Data Source
      KAKENHI-PROJECT-18390315
  • [Presentation] ヒト毛乳頭のmolecular signatureの解析-毛乳頭細胞の何が特別なのか?-2007

    • Author(s)
      大山学、清水篤、天谷雅行
    • Organizer
      第14回分子皮膚科学フォーラム
    • Place of Presentation
      松山
    • Year and Date
      2007-09-15
    • Data Source
      KAKENHI-PROJECT-18390315
  • [Presentation] ヒト毛乳頭のmolecular signatureの解析-毛乳頭細胞の何が特別なのか2007

    • Author(s)
      大山 学, 他2名
    • Organizer
      日本研究皮膚科学会第31回年次学術大会
    • Place of Presentation
      松山
    • Year and Date
      2007-09-15
    • Data Source
      KAKENHI-PROJECT-18390315
  • [Presentation] ヒトiPS細胞由来LNGFR(+)THY-1(+) 間葉系幹細胞を用いた毛誘導能をもつ細胞の作成

    • Author(s)
      大山 学、Ophelia Veraitch、馬渕 洋、松崎有未、佐々木貴史、塚島明希、天谷雅行、岡野栄之
    • Organizer
      第14回日本再生医療学会
    • Place of Presentation
      パシフィコ横浜(神奈川県、横浜市)
    • Year and Date
      2015-03-19 – 2015-03-21
    • Data Source
      KAKENHI-PROJECT-25293246
  • [Presentation] Promise of human iPS cells for hair follicle regeneration

    • Author(s)
      Manabu Ohyama
    • Organizer
      8th World Congress of Hair Research
    • Place of Presentation
      済州島(韓国)
    • Year and Date
      2014-05-14 – 2014-05-17
    • Invited
    • Data Source
      KAKENHI-PROJECT-25293246
  • [Presentation] Advantages of using human iPS cells for hair follicle bioengineering

    • Author(s)
      Manabu Ohyama
    • Organizer
      British Society for Investigative Dermatology Meeting 2014
    • Place of Presentation
      ニューキャッスル(イギリス)
    • Year and Date
      2014-04-07 – 2014-04-09
    • Invited
    • Data Source
      KAKENHI-PROJECT-25293246
  • [Presentation] Use of human induced pluripotent stem cell-derived CD271+CD90+ mesenchymal stem cells for the generation of hair inductive dermal cells

    • Author(s)
      Ophelia Veraitch, Yo Mabuchi, Yumi Matsuzaki, Takashi Sasaki, Aki Tsukashima, Masayuki Amagai, Hideyuki Okano, Manabu Ohyama
    • Organizer
      The 39th Annual Meeting of the Japanese Society for Investigative Dermatology
    • Place of Presentation
      ホテル阪急エキスポパーク(大阪府、吹田市)
    • Year and Date
      2014-12-12 – 2014-12-14
    • Data Source
      KAKENHI-PROJECT-25293246
  • [Presentation] Current strategy to enhance epithelial-mesenchymal interactions for human hair follicle bioengineering

    • Author(s)
      Manabu Ohyama
    • Organizer
      8th World Congress of Hair Research
    • Place of Presentation
      済州島(韓国)
    • Year and Date
      2014-05-14 – 2014-05-17
    • Invited
    • Data Source
      KAKENHI-PROJECT-25293246
  • [Presentation] Induction of dermal papilla properties in highly potent CD271+CD90+mesenchymal stem cells generated from human-induced pluripotent stem cells

    • Author(s)
      Ophelia Veraitch, Yo Mabuchi, Yumi Matsuzaki, Masayuki Amagai, Hideyuki Okano, Manabu Ohyama
    • Organizer
      British Society for Investigative Dermatology Meeting 2014
    • Place of Presentation
      ニューキャッスル(イギリス)
    • Year and Date
      2014-04-07 – 2014-04-09
    • Data Source
      KAKENHI-PROJECT-25293246
  • 1.  MASAYUKI Amagai (90212563)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 16 results
  • 2.  NISHIKAWA Takeji (50051579)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 3.  IWASAKI Toshiro (50262754)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 21 results
  • 4.  KUBO Akiharu (70335256)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 5.  ISHIKO Akira (10202988)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  NISHIFUJI Koji (20365422)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 5 results
  • 7.  HIDEYUKI OKANO (60160694)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 7 results
  • 8.  SAITO Masataka (30306774)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  NAGAO Keisuke (40286521)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 10.  SHIROTA Kinji (70149322)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  KOYASU Shigeo (90153684)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  TANAKA Masaru (40188339)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  ANZAI Hidemi (90276345)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  Kinoshita Misaki (40594594)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 15.  布袋 祐子 (40265898)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  代田 欣二 (70147974)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  鈴木 春巳 (70235985)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  高橋 良 (00317091)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  佐藤 洋平 (90736307)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  TSUKASHIMA AKI
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results

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