Sasaki Yukio 佐々木幸生

… Alternative Names

Yukio Sasaki 佐々木幸生

SASAKI Yukio 佐々木幸生

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Researcher Number	10295511
Other IDs
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Affiliation (Current)	2025: 横浜市立大学, 生命医科学研究科, 准教授
Affiliation (based on the past Project Information) *help	2020 – 2023: 横浜市立大学, 生命医科学研究科, 准教授 2014 – 2018: 横浜市立大学, 生命医科学研究科, 准教授 2013: 横浜市立大学, その他の研究科, 准教授 2012: 横浜市立大学, 医学(系)研究科(研究院), 特任准教授 2010 – 2012: 横浜市立大学, 医学研究科, 特任准教授 2000 – 2002: 横浜市立大学, 医学部, 講師 1998 – 1999: 横浜市立大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Basic Section 46010:Neuroscience-general-related / Neurochemistry/Neuropharmacology / Neurochemistry/Neuropharmacology / Biological Sciences / Neurochemistry/Neuropharmacology Except Principal Investigator General medical chemistry / General pharmacology / Biological Sciences
Keywords	Principal Investigator 神経生物学 / 横浜市 / 脆弱X症候群 / セマフォリン / 成長円錐 / 相分離 / 液－液相分離 / RNA結合タンパク質 / RNA顆粒 / マイクロRNA … More / 軸索輸送 / Cdk5 / Fyn / チロシンキナーゼ / FMRP / 光遺伝学 / 液-液相分離 / 自閉スペクトラム症 / ユビキチン / プロテオミクス / シナプス / マイクロ RNA / 翻訳調節 / 分子・細胞・神経生物学 / 軸策輸送 / 神経細胞死 / 神経ガイダンス / ラベンダスチンA / プレキシン / チロシンリン酸化 / 神経回路網 / コラプシン / セマホリン / 神経発生 / 軸索ガイダンス / 反発因子 … More Except Principal Investigator 細胞内情報伝達 / プレキシン / チロシンホスファターゼ / セマフォリン / 4血管閉塞脳虚血 / 神経細胞死因子ドーパ / Signal Transduction / Axon guidance / Plexin / Semaphorin / Protein tyrosine Phosphatase / チロシンリン酸化 / 神経回路形成 / hippocampus / transporter / neuronal cell death / ischemia / striatum / baroreceptor reflex / nucleus tractus solitarii / L-DOPA / 脳虚血グルタミン酸誘発上流因子内因性ドーパ / ドーパトランスポーター / 高電位活性化Ca^<2+>チャネル電流促進 / 孤束核単離細胞 / 孤束核-尾側腹外側延髄ドーパ性投射 / 圧受容器情報伝達物質ドーパ / 海馬 / トランスポーター / 神経細胞死 / 虚血 / 線条体 / 圧受容体反射 / 弧束核 / L-ドーパ / 成長円錐 / ニューロピリン / PTPase / Nogo / 新規競合的拮抗薬DOPA cyclohxyl ester同保護 / ドーパ脱炭酸酵素阻害薬神経細胞死増悪 / グルタミン酸遊離 / 線条体微量透析 / 胎仔線条体神経細胞培養系 / 脳虚血上流因子内因性ドーパ Less

Mechanism of formation of neuronal transport granules and their role in axon elongation and synaptogenesis - relationship to phase separationPrincipal Investigator
- Principal Investigator
  
  佐々木幸生
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 46010:Neuroscience-general-related
- Research Institution
  Yokohama City University
RNA granule-mediated regulation for local translation and presynapse formation: relation between phase separation and synapse granulesPrincipal Investigator
- Principal Investigator
  
  Yukio Sasaki
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 46010:Neuroscience-general-related
- Research Institution
  Yokohama City University
Regulation of neural circuit by Fragile X Mental Retardation Protein - its relation to ubiquitination and local translationPrincipal Investigator
- Principal Investigator
  
  Yukio Sasaki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Yokohama City University
Role of local protein synthesis regulated by Fragile X Mental Retardation Protein during presynapse formationPrincipal Investigator
- Principal Investigator
  
  SASAKI Yukio
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Yokohama City University
マイクロＲＮＡの輸送マシナリーの解明と軸索機能における役割Principal Investigator
- Principal Investigator
  
  佐々木幸生
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Yokohama City University
Role of growth cone autonomy and translational trans-acting factors in axon guidancePrincipal Investigator
- Principal Investigator
  
  SASAKI Yukio
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Yokohama City University
神経細胞死における成長円錐と細胞体のダイアログPrincipal Investigator
- Principal Investigator
  
  佐々木幸生
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Yokohama City University
The relation between LAR class protein tyrosine phosphates and Semaphorin-Plexin signaling
- Principal Investigator
  
  NAKAMURA Fumio
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Yokohama City University, School of Medicine
軸索伸長抑制因子Nogoの受容体同定とセマフォリンの細胞内情報伝達系の解明
- Principal Investigator
  
  NAKAMURA Fumio
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Yokohama City University
コラプシンによる細胞運動抑制とチロシンリン酸化相関の解析Principal Investigator
- Principal Investigator
  
  佐々木幸生
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Yokohama City University
ドーパはグルタミン酸遊離-神経細胞死の上流因子か? ドーパ新競合的拮抗薬の保護作用
- Principal Investigator
  
  三須良實
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Yokohama City University
L-DOPA Plays a role as a neurotransmitter regulating blood pressure in the lower brain stem, and endogenously evoked L-DOPA is a casual factor for glutamate release and resultant delayed neuronal cell death by transient ischemia in rats
- Principal Investigator
  
  GOSHIMA Yoshio, 三須良實
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Yokohama City University

All 2023 2022 2021 2020 2018 2017 2016 2015 2014 2013 2012 2011 2010

All Journal Article Presentation

[Journal Article] Novel presynaptic assay system revealed that metformin ameliorates exaggerated synaptic release and Munc18-1 accumulation in presynapses of neurons from Fragile X syndrome mouse model2023
- Author(s)
  Takeda Renoma、Ishii Rie、Parvin Shumaia、Shiozawa Aki、Nogi Terukazu、Sasaki Yukio
- Journal Title
  
  Neuroscience Letters
  
  Volume: 810 Pages: 137317-137317
- DOI
  10.1016/j.neulet.2023.137317
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K05964
[Journal Article] RNA 顆粒と神経細胞のRNA 輸送・局所翻訳2022
- Author(s)
  藤原睦也、佐々木幸生
- Journal Title
  
  月刊「細胞」
  
  Volume: 54 Pages: 478-482
- Data Source
  KAKENHI-PROJECT-20K06877
[Journal Article] Local Translation in Growth Cones and Presynapses, Two Axonal Compartments for Local Neuronal Functions2020
- Author(s)
  Sasaki Yukio
- Journal Title
  
  Biomolecules
  
  Volume: 10 Issue: 5 Pages: 668-668
- DOI
  10.3390/biom10050668
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K06877
[Journal Article] Identification of FMRP target mRNAs in the developmental brain: FMRP might coordinate Ras/MAPK, Wnt/β-catenin, and mTOR signaling during corticogenesis2020
- Author(s)
  Casingal Cristine R.、Kikkawa Takako、Inada Hitoshi、Sasaki Yukio、Osumi Noriko
- Journal Title
  
  Molecular Brain
  
  Volume: 13 Issue: 1 Pages: 1-13
- DOI
  10.1186/s13041-020-00706-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K06877, KAKENHI-PROJECT-20K07237, KAKENHI-INTERNATIONAL-16K21734, KAKENHI-ORGANIZER-16H06524, KAKENHI-PLANNED-16H06530, KAKENHI-PROJECT-19H03318
[Journal Article] Semaphorin-3A Promotes Degradation of Fragile X Mental Retardation Protein in Growth Cones via the Ubiquitin-Proteasome Pathway2020
- Author(s)
  Takabatake Masaru、Goshima Yoshio、Sasaki Yukio
- Journal Title
  
  Frontiers in Neural Circuits
  
  Volume: 14 Pages: 1-9
- DOI
  10.3389/fncir.2020.00005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K06877
[Journal Article] Fragile X mental retardation protein regulates accumulation of the active zone protein Munc18-1 in presynapses via local translation in axons during synaptogenesis.2018
- Author(s)
  Parvin S, Takeda R, Sugiura Y, Neyazaki M, Nogi T, Sasaki Y.
- Journal Title
  
  Neurosci Res.
  
  Volume: S0168-0102 Pages: 30431-0
- DOI
  10.1016/j.neures.2018.09.013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K19206, KAKENHI-PROJECT-16K07061
[Journal Article] Regulation of dendritic development by Semaphorin 3A through novel intracellular remote signaling2016
- Author(s)
  Goshima Y, Yamashita N, Nakamura F, Sasaki Y
- Journal Title
  
  Cell Adh Migr
  
  Volume: 10 Issue: 6 Pages: 627-640
- DOI
  10.1080/19336918.2016.1210758
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07061, KAKENHI-PROJECT-16K07062, KAKENHI-PROJECT-16K10168
[Journal Article] Identification of axon-enriched MicroRNAs localized to growth cones of cortical neurons.2014
- Author(s)
  Sasaki Y, Gross C, Xing L, Goshima Y, Bassell GJ.
- Journal Title
  
  Dev Neurobiol
  
  Volume: 74 Issue: 3 Pages: 397-406
- DOI
  10.1002/dneu.22113
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24115713, KAKENHI-PROJECT-25430068
[Journal Article] lexinA4-dependent retrograde Semaphorin3A signaling regulates the dendritic localization of GluA2-containing AMPA receptors.2014
- Author(s)
  1) Yamashita, N., Usui, H., Nakamura, F., Chen, S., Sasaki, Y., Hida, T., Suto, F., Taniguchi, M., Takei, K., Goshima, Y.
- Journal Title
  
  Nature Communications
  
  Volume: 5 Issue: 1 Pages: 3424-3424
- DOI
  10.1038/ncomms4424
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23500452, KAKENHI-PUBLICLY-24111539, KAKENHI-PUBLICLY-24115713, KAKENHI-PROJECT-24500443, KAKENHI-PROJECT-24500444, KAKENHI-PROJECT-24590236, KAKENHI-PROJECT-25430031, KAKENHI-PUBLICLY-26111718, KAKENHI-PROJECT-26290024
[Journal Article] Plexin-A4-dependent retrograde semaphorin 3A signalling regulates the dendritic localization of GluA2-containing AMPA receptors.2014
- Author(s)
  Yamashita N, Usui H, Nakamura F, Chen S, Sasaki Y, Hida T, Suto F, Taniguchi M, Takei K, Goshima Y.
- Journal Title
  
  Nat Commun
  
  Volume: 5 Pages: 3424-3424
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25430068
[Journal Article] Regulation of neurite outgrowth mediated by localized phosphorylation of protein translational factor eEF2 in growth cones2013
- Author(s)
  Iketani M., Iizuka A., Sengoku K., Kurihara Y., Nakamura F., Sasaki Y., Sato Y., Yamane M., Matsushita M., Nairn A.C., Takamatsu K., Goshima Y., Takei K.
- Journal Title
  
  Dev. Neurosci
  
  Volume: 73 Issue: 3 Pages: 230-246
- DOI
  10.1002/dneu.22058
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500336, KAKENHI-PROJECT-23500452, KAKENHI-PROJECT-24890187, KAKENHI-PUBLICLY-24111539, KAKENHI-PUBLICLY-24115713
[Journal Article] Class 3 semaphorins as a therapeutic target2012
- Author(s)
  Goshima Y., Sasaki Y., Yamashita N., Nakamura F
- Journal Title
  
  Expert Opin.Ther. Targets
  
  Volume: 16 Issue: 9 Pages: 933-944
- DOI
  10.1517/14728222.2012.710201
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500336, KAKENHI-PROJECT-24500444, KAKENHI-PUBLICLY-24115713
[Journal Article] 神経軸索・成長円錐における局所翻訳制御と機能調節2012
- Author(s)
  佐々木幸生、五嶋良郎
- Journal Title
  
  細胞工学
  
  Volume: 31 Pages: 677-682
- Data Source
  KAKENHI-PROJECT-22500336
[Journal Article] GSK3β/axin-1/β-catenin complex is involved in semaphorin3A signaling.2012
- Author(s)
  Hida T., Yamashita N., Usui H., Nakamura F.Sasaki Y., Kikuchi A.Goshima Y.
- Journal Title
  
  J. Neurosci
  
  Volume: 32 Issue: 35 Pages: 11905-11918
- DOI
  10.1523/jneurosci.6139-11.2012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500336, KAKENHI-ORGANIZER-23112001, KAKENHI-PLANNED-23112004, KAKENHI-PUBLICLY-24115713
[Journal Article] 神経軸索・成長円錐における局所翻訳制御と機能調節2012
- Author(s)
  佐々木幸生.. .五嶋良郎
- Journal Title
  
  細胞工学
  
  Volume: 31 Pages: 677-682
- Data Source
  KAKENHI-PUBLICLY-24115713
[Journal Article] CRMP5(collapsin response mediator protein 5) regulates dendritic development and synaptic plasticity in the cerebellar Purkinje cells2011
- Author(s)
  Yamashita N, Mosinger B, Roy A, Miyazaki M, Ugajin K, Nakamura F, Sasaki Y, Yamaguchi K, Kolattukudy P, Goshima Y.
- Journal Title
  
  Journal of Neuroscience
  
  Volume: 31(5) Issue: 5 Pages: 1773-79
- DOI
  10.1523/jneurosci.5337-10.2011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21700411, KAKENHI-PROJECT-22500336, KAKENHI-PROJECT-23500472
[Journal Article] CRMP5(Collapsin Response Mediator Protein 5) Regulates Dendritic Development and Synaptic Plasticity in the Cerebellar Purkinje Cells.2011
- Author(s)
  Yamashita, N., Mosinger, B., Roy, A., Miyazaki, M., Ugajin, K., Nakamura, F., Sasaki, Y., Yamaguchi, K., Kolattukudy, P., Goshima, Y.
- Journal Title
  
  J.Neurosci.
  
  Volume: 31 Pages: 1773-1779
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500336
[Journal Article] Regulation of chemotropic guidance of nerve growth cones by microRNA2011
- Author(s)
  Han, L., Wen, Z., Lynn, R. C., Baudet, M. L., Holt, C. E., Sasaki, Y., Bassell, G. J., Zheng, J. Q
- Journal Title
  
  Mol. Brain
  
  Volume: 4 Issue: 1 Pages: 40-40
- DOI
  10.1186/1756-6606-4-40
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500336
[Journal Article] Phosphorylation of zipcode binding protein is required for BDNF signaling of local β-actin synthesis and growth cone turning2011
- Author(s)
  Sasaki, Y., Welshhans, K., Wen, Z., Yao, J., Xu, M., Goshima, Y., Zheng, J. Q., Bassell, G. J.
- Journal Title
  
  J. Neurosci
  
  Volume: 30 Issue: 28 Pages: 9349-9358
- DOI
  10.1523/jneurosci.0499-10.2010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500336
[Journal Article] Phosphorylation of zipcode binding protein is required for BDNF signaling of local β-actin synthesis and growth cone turning.2010
- Author(s)
  Sasaki, Y., Welshhans, K., Wen, Z., Yao, J., Xu, M., Goshima, Y., Zheng, J.Q., Bassell, G.J.
- Journal Title
  
  J.Neurosci.
  
  Volume: 30 Pages: 9349-9358
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500336
[Presentation] 液液相分離の光遺伝学的制御による皮質ニューロンの神経突起における脆弱X精神遅滞タンパク質含有RNA顆粒の可逆的形成2023
- Author(s)
  佐々木　幸生、藤原　睦也
- Organizer
  神経科学学会
- Data Source
  KAKENHI-PROJECT-23K05964
[Presentation] 光遺伝学的な液-液相分離制御による脆弱X精神遅滞タンパク質含有顆粒形成の神経細胞内における操作2022
- Author(s)
  藤原睦也、佐々木幸生
- Organizer
  日本分子生物学会
- Data Source
  KAKENHI-PROJECT-20K06877
[Presentation] 糖尿病治療薬メトホルミンは脆弱X症候群モデルマウスの神経細胞のプレシナプスにおいて生じる過剰なシナプス分泌とMunc18-1の蓄積を改善する2021
- Author(s)
  佐々木幸生、武田怜之雅、石井理愛、塩澤亜希、禾晃和、Shumaia Parvin
- Organizer
  日本神経科学学会
- Data Source
  KAKENHI-PROJECT-20K06877
[Presentation] 脆弱X精神遅滞タンパク質のRNA結合ドメイン欠損変異体の過剰発現はRNA顆粒形成を阻害する2021
- Author(s)
  藤原睦也、佐々木幸生
- Organizer
  日本分子生物学会
- Data Source
  KAKENHI-PROJECT-20K06877
[Presentation] 人工誘導プレシナプスを用いた神経活動計測系の開発2017
- Author(s)
  武田怜之雅、Shumaia Parvin、佐々木幸生
- Organizer
  第136回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-16K07061
[Presentation] 脆弱X精神遅滞タンパク質によるシナプス前終末の形成と機能の制御2017
- Author(s)
  佐々木幸生、Shumaia Parvin、武田怜之雅
- Organizer
  第39回神経組織培養研究会
- Data Source
  KAKENHI-PROJECT-16K07061
[Presentation] マイクロRNA382のエクソソームを介した分泌機構と標的遺伝子の解析2017
- Author(s)
  木村貴洋、田中智美、佐々木幸生
- Organizer
  第137回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-16K07061
[Presentation] Fragile X mental retardation protein regulates accumulation of the active zone protein Munc18 in presynapses via local translation.2017
- Author(s)
  Shumaia Parvin, Renoma Takeda, Shino Endo, Yu Sugiura, Yukio Sasaki
- Organizer
  第40回神経科学学会
- Data Source
  KAKENHI-PROJECT-16K07061
[Presentation] 脆弱X精神遅滞タンパク質の分解と神経回路形成2016
- Author(s)
  佐々木　幸生、高畠　将
- Organizer
  第38回神経組織培養研究会
- Place of Presentation
  横浜ランドマークタワー（神奈川県横浜市）
- Data Source
  KAKENHI-PROJECT-16K07061
[Presentation] 脆弱X精神遅滞タンパク質に対するユビキチンリガーゼの同定の試み2016
- Author(s)
  高畠　将、高橋　徹、梁　明秀、五嶋　良郎、佐々木　幸生
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Data Source
  KAKENHI-PROJECT-16K07061
[Presentation] 大脳皮質神経細胞培養系において脱分極刺激により特定のマイクロRNAがエクソソーム中に増加する2016
- Author(s)
  田中　智美、高橋　徹、佐々木　幸生
- Organizer
  第134回日本薬理学会関東部会
- Place of Presentation
  国際医療福祉大学（栃木県大田原市）
- Data Source
  KAKENHI-PROJECT-16K07061
[Presentation] シナプス前終末形成過程におけるマイクロRNA結合タンパク質Argonaute2の局在変化2015
- Author(s)
  高橋　徹、杉浦　侑、佐々木　幸生
- Organizer
  第38回日本分子生物学会年会、第88回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートピアアイランド（兵庫県神戸市）
- Year and Date
  2015-12-03
- Data Source
  KAKENHI-PROJECT-25430068
[Presentation] セマフォリン3Aは脆弱X精神遅滞タンパク質のユビキチン化を誘導する2014
- Author(s)
  高畠　将、五嶋　良郎、佐々木　幸生
- Organizer
  第130回日本薬理学会関東部会
- Place of Presentation
  星薬科大学(東京都品川区）
- Year and Date
  2014-07-05
- Data Source
  KAKENHI-PROJECT-25430068
[Presentation] Proteomics of axons during presynapse formation using the novel culture method "neuron ball culture"2013
- Author(s)
  Sasaki Y, Ishikawa A, Kawakami T, Hirano H, Goshima Y.
- Organizer
  12th HUPO
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PUBLICLY-24115713
[Presentation] Proteomics of axons during presynapse formation using the novel culture method "neuron ball culture"2013
- Author(s)
  Sasaki Y, Ishikawa A, Kawakami T, Hirano H, Goshima Y.
- Organizer
  12th HUPO
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-25430068
[Presentation] 脆弱X精神遅滞タンパク質の軸索・成長円錐における局在はセマフォリン3Aにより制御される2013
- Author(s)
  佐々木　幸生、髙畠　将、花岡　和則、五嶋　良郎
- Organizer
  第36回日本神経科学大会、第56回日本神経化学会大会、第23回日本神経回路学会大会合同大会（Neuro2013）
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-25430068
[Presentation] 新規培養法「ニューロンボール法」を用いたシナプス前終末形成のプロテオーム解析2013
- Author(s)
  佐々木　幸生
- Organizer
  第35回神経組織培養研究会
- Place of Presentation
  吹田
- Data Source
  KAKENHI-PROJECT-25430068
[Presentation] セマフォリン 3Aによる脆弱X精神遅滞タンパク質の局在制御2013
- Author(s)
  高畠　将、五嶋　良郎、佐々木　幸生
- Organizer
  第15回RNA学会年会
- Place of Presentation
  松山
- Data Source
  KAKENHI-PROJECT-25430068
[Presentation] 翻訳トランス因子による軸索局所翻訳制御と神経疾患との関2013
- Author(s)
  佐々木幸生
- Organizer
  連日本生理学会(招待講演)
- Place of Presentation
  タワーホール船堀(東京都)。
- Year and Date
  2013-03-28
- Data Source
  KAKENHI-PROJECT-22500336
[Presentation] 翻訳トランス因子による軸索局所翻訳制御と神経疾患との関連2013
- Author(s)
  佐々木　幸生
- Organizer
  日本生理学会
- Place of Presentation
  タワーホール船堀（東京）
- Invited
- Data Source
  KAKENHI-PROJECT-22500336
[Presentation] 新規培養法「ニューロンボール法」を用いたシナプス前終末形成のプロテオーム解析2013
- Author(s)
  佐々木　幸生
- Organizer
  第35回神経組織培養研究会
- Place of Presentation
  吹田
- Data Source
  KAKENHI-PUBLICLY-24115713
[Presentation] 翻訳トランス因子による軸索局所翻訳制御と神経疾患との関連2013
- Author(s)
  佐々木　幸生
- Organizer
  日本生理学会
- Place of Presentation
  タワーホール船堀（東京）
- Year and Date
  2013-03-27
- Invited
- Data Source
  KAKENHI-PUBLICLY-24115713
[Presentation] セマフォリン 3Aによる脆弱X精神遅滞タンパク質の局在制御2013
- Author(s)
  高畠　将、五嶋　良郎、佐々木　幸生
- Organizer
  第15回RNA学会年会
- Place of Presentation
  松山
- Data Source
  KAKENHI-PUBLICLY-24115713
[Presentation] 脆弱X精神遅滞タンパク質の軸索・成長円錐における局在はセマフォリン3Aにより制御される2013
- Author(s)
  佐々木　幸生、髙畠　将、花岡　和則、五嶋　良郎
- Organizer
  第36回日本神経科学大会、第56回日本神経化学会大会、第23回日本神経回路学会大会合同大会（Neuro2013）
- Place of Presentation
  京都
- Data Source
  KAKENHI-PUBLICLY-24115713
[Presentation] セマフォリン3Aによる脆弱X精神遅滞タンパク質のユビキチン化2013
- Author(s)
  高畠　将、五嶋　良郎、佐々木　幸生
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PUBLICLY-24115713
[Presentation] Identification of axonal microRNAs reveals involvement of miR-720 in neurotrophin-regulated axonal growth2012
- Author(s)
  Sasaki Y,Xing L, Gross C, Goshima Bassell GJ
- Organizer
  The 22nd CDB Meeting, RNA Sciences in Cell and Developmental Biology II
- Place of Presentation
  理研CDB（兵庫）
- Year and Date
  2012-06-11
- Data Source
  KAKENHI-PUBLICLY-24115713
[Presentation] Identification of axonal microRNAs reveals involvement of miR-720 in neurotrophin-regulated axonal growth2012
- Author(s)
  Sasaki Y,Xing L, Gross C, Goshima Bassell GJ
- Organizer
  The 22nd CDB Meeting, RNA Sciences in Cell and Developmental Biology II
- Place of Presentation
  理研CDB（兵庫）
- Data Source
  KAKENHI-PROJECT-22500336
[Presentation] 神経軸索におけるマイクロ RNA オミクスにより同定された miRNA-720 は神経栄養因子による軸索伸長に関与する2012
- Author(s)
  佐々木幸生.Xing, L.、Gross C.、五嶋良郎, Bassell, G. J
- Organizer
  日本 RNA 学会
- Place of Presentation
  東北大学百周年記念会館川内萩ホール(宮城県)
- Year and Date
  2012-07-20
- Data Source
  KAKENHI-PROJECT-22500336
[Presentation] Identification of axonal microRNAs reveals involvement of miR-720 in neurotrophin-regulated axonal growth2012
- Author(s)
  Sasaki Y., Xing L., Gross C., Goshima, Y., Bassell G.J.
- Organizer
  The 22nd CDB Meeting, RNA Sciences in Cell and Developmental Biology II
- Place of Presentation
  理化学研究所発生・再生科学総合研究センター(兵庫県)
- Year and Date
  2012-06-13
- Data Source
  KAKENHI-PROJECT-22500336
[Presentation] 神経軸索におけるマイクロRNAオミクスにより同定されたmiRNA-720は神経栄養因子による軸索伸長に関与する2012
- Author(s)
  佐々木　幸生、Lei Xing、Christina Gross、五嶋　良郎, Gary J. Bassell
- Organizer
  日本RNA学会
- Place of Presentation
  東北大学（宮城）
- Data Source
  KAKENHI-PROJECT-22500336
[Presentation] 神経軸索におけるマイクロRNAオミクスにより同定されたmiRNA-720は神経栄養因子による軸索伸長に関与する2012
- Author(s)
  佐々木　幸生、.. Lei Xing、.. Christina Gross、五嶋良郎.. , Gary J. Bassell
- Organizer
  日本RNA学会
- Place of Presentation
  東北大学（宮城）
- Year and Date
  2012-07-18
- Data Source
  KAKENHI-PUBLICLY-24115713
[Presentation] Brain-derived neurotrophic factor regulates localization of microRNA-720 in growth cones2011
- Author(s)
  Sasaki, Y., Xing, L., Gross, C., Goshima, Y., and Bassell, G. J
- Organizer
  第34回日本神経科学大会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2011-09-16
- Data Source
  KAKENHI-PROJECT-22500336
[Presentation] Brain-derived neurotrophic factor regulates localization of microRNA-720 in growth cones2011
- Author(s)
  佐々木幸生, Xing, L., Gross, C., 五嶋良郎., Bassell, G.J.
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  国立京都国際会館(京都)
- Year and Date
  2011-09-24
- Data Source
  KAKENHI-PROJECT-22500336
[Presentation] Brain-derived neurotrophic factor regulates localization of microRNA-720 in growth cones2011
- Author(s)
  佐々木幸生, Xing, L., Gross, C.五嶋良郎, Bassell, G. J
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  国立京都国際会館(京都府)。
- Year and Date
  2011-09-24
- Data Source
  KAKENHI-PROJECT-22500336
[Presentation] Brain-derived neurotrophic factor regulates localization of microRNA-720 in growth cones2011
- Author(s)
  Sasaki, Y., Xing, L., Gross, C., Goshima, Y., Bassell, G.J.
- Organizer
  第34回日本神経科学大会
- Place of Presentation
  パシフィコ横浜(横浜)
- Year and Date
  2011-09-16
- Data Source
  KAKENHI-PROJECT-22500336
[Presentation] Profiling of microRNAs enriched in axons2010
- Author(s)
  Sasaki Y., Xing, L., Gross, C., Goshima, Y., Bassell, G.J
- Organizer
  第33回日本神経科学大会
- Place of Presentation
  神戸コンベンションセンター(兵庫県) 。
- Year and Date
  2010-09-04
- Data Source
  KAKENHI-PROJECT-22500336
[Presentation] Profiling of microRNAs enriched in axons2010
- Author(s)
  Yukio Sasaki, Lei Xing, Christina Gross, Yoshio Goshima, Gary J.Bassell
- Organizer
  第33回日本神経科学大会
- Place of Presentation
  神戸国際会議場(神戸)
- Year and Date
  2010-09-04
- Data Source
  KAKENHI-PROJECT-22500336

1. GOSHIMA Yoshio (00153750)

# of Collaborated Projects: 4 results

# of Collaborated Products: 18 results
2. MIYAMAE Takeaki (00239435)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. NAKAMURA Fumio (10262023)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 三須良實 (10025687)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 古川信也 (90285114)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. KAWAKAMI Takao (40366117)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. OGURA Ken-ichi (20326028)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. Ito Hidenori

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. YAMASHITA Naoya

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 竹居光太郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 禾晃和

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Sasaki Yukio 佐々木 幸生

Yukio Sasaki 佐々木 幸生

SASAKI Yukio 佐々木 幸生

Research Projects

Research Products

Co-Researchers

Mechanism of formation of neuronal transport granules and their role in axon elongation and synaptogenesis - relationship to phase separationPrincipal Investigator

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RNA granule-mediated regulation for local translation and presynapse formation: relation between phase separation and synapse granulesPrincipal Investigator

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Regulation of neural circuit by Fragile X Mental Retardation Protein - its relation to ubiquitination and local translationPrincipal Investigator

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Role of local protein synthesis regulated by Fragile X Mental Retardation Protein during presynapse formationPrincipal Investigator

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マイクロＲＮＡの輸送マシナリーの解明と軸索機能における役割Principal Investigator

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Role of growth cone autonomy and translational trans-acting factors in axon guidancePrincipal Investigator

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神経細胞死における成長円錐と細胞体のダイアログPrincipal Investigator

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The relation between LAR class protein tyrosine phosphates and Semaphorin-Plexin signaling

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軸索伸長抑制因子Nogoの受容体同定とセマフォリンの細胞内情報伝達系の解明

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コラプシンによる細胞運動抑制とチロシンリン酸化相関の解析Principal Investigator

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ドーパはグルタミン酸遊離-神経細胞死の上流因子か? ドーパ新競合的拮抗薬の保護作用

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L-DOPA Plays a role as a neurotransmitter regulating blood pressure in the lower brain stem, and endogenously evoked L-DOPA is a casual factor for glutamate release and resultant delayed neuronal cell death by transient ischemia in rats

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[Journal Article] Novel presynaptic assay system revealed that metformin ameliorates exaggerated synaptic release and Munc18-1 accumulation in presynapses of neurons from Fragile X syndrome mouse model2023

Author(s)

Journal Title

Sasaki Yukio 佐々木幸生

Yukio Sasaki 佐々木幸生

SASAKI Yukio 佐々木幸生