hayashi keitaro 林啓太朗

… Alternative Names

Hayashi Keitaro 林啓太朗

HAYASHI Keitaro 林啓太朗

Less

Researcher Number	10323106
Affiliation (Current)	2025: 獨協医科大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2017 – 2024: 獨協医科大学, 医学部, 准教授 2012 – 2015: 獨協医科大学, 医学部, 准教授 2011: 獨協医科大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 47040:Pharmacology-related / General pharmacology Except Principal Investigator Basic Section 55040:Respiratory surgery-related / Respiratory surgery / Kidney internal medicine / General pharmacology
Keywords	Principal Investigator アミノ酸トランスポーター / T細胞 / LAT1 / アルギニンメチル化 / JPH203 / 自己免疫疾患 / 飢餓応答 / 免疫疾患 / タンパクメチル化 / T 細胞 … More / 薬理学 / 骨代謝 / サイトカイン / アミノ酸飢餓応答 / 遺伝子発現制御 / ヒト破骨細胞 / アミノ酸飢餓応答反応 / 破骨細胞 / アミノ酸欠乏ストレス反応 / アミノ酸欠乏ストレス応答 … More Except Principal Investigator 胸腺癌 / トランスポーター / スタチン / MAPK7 / LAT1 / アミノ酸トランスポーター / 胸腺腫 / 希少がん / 抗腫瘍活性 / 胸腺 / 癌 / 胸腺上皮性腫瘍 / 腎臓 / 翻訳後修飾 / 蛋白質 / 遺伝子 / 薬理学 / 腎尿細管 / 高尿酸血症 / 痛風 / 尿酸 Less

LAT1-EWSR1 axisを標的とした新たな免疫疾患治療戦略の開発Principal Investigator
- Principal Investigator
  
  林啓太朗
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Dokkyo Medical University
HMGCR-MAPK7 axisを標的とした新たな胸腺癌治療戦略の開発
- Principal Investigator
  
  千田雅之
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Dokkyo Medical University
LAT1によるアルギニンメチル化調節を介した新規T細胞活性化機構の解明Principal Investigator
- Principal Investigator
  
  林啓太朗
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Dokkyo Medical University
HMG-CoA還元酵素を標的とした胸腺癌に対する新たな治療戦略の構築
- Principal Investigator
  
  千田雅之
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Dokkyo Medical University
Suppressive effects of LAT1-specific inhibitor on osteoclastgenesisPrincipal Investigator
- Principal Investigator
  
  Hayashi Keitaro
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Dokkyo Medical University
Development of new therapeutic strategies for thymic carcinoma targeting LAT1
- Principal Investigator
  
  Chida Masayuki
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory surgery
- Research Institution
  Dokkyo Medical University
Strategy for epithelial thymic malignancy treatment focusing on L-type amino acid transporter 1
- Principal Investigator
  
  CHIDA MASAYUKI
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Respiratory surgery
- Research Institution
  Dokkyo Medical University
Role of LAT1 in T cell activationPrincipal Investigator
- Principal Investigator
  
  HAYASHI Keitaro
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Dokkyo Medical University
Novel regulatory mechanism of renaltubular transporter function by SUMOylation-deSUMOylation
- Principal Investigator
  
  ANZAI Naohiko
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Kidney internal medicine
- Research Institution
  Dokkyo Medical University
New drug development for hyperuricemia targeting novel urate efflux transporter URATv1
- Principal Investigator
  
  ANZAI Naohiko
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Dokkyo Medical University
  Kyorin University

All 2023 2022 2021 2020 2019 2018 2017 2015 2014 2013 2012 2011 Other

All Journal Article Presentation Book Patent

[Book] ハートナップ病、別冊日本臨床新領域別症候群シリーズNo. 20 先天性代謝異常症候群(第2版)2012
- Author(s)
  安西尚彦、花田健治、林啓太朗
- Data Source
  KAKENHI-PROJECT-23659447
[Journal Article] Hamster Sperm Possess Functional Na+/Ca2+-Exchanger 1: Its Implication in Hyperactivation2023
- Author(s)
  Takei Gen L.、Ogura Yuhei、Ujihara Yoshihiro、Toyama Fubito、Hayashi Keitaro、Fujita Tomoe
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 24 Issue: 10 Pages: 8905-8905
- DOI
  10.3390/ijms24108905
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06581, KAKENHI-PROJECT-21K09378, KAKENHI-PROJECT-22K19934, KAKENHI-PROJECT-23K21852
[Journal Article] JPH203, a LAT1 inhibitor, alleviates steroid‐resistant murine airway inflammation mediated by Th17 cells2023
- Author(s)
  Hayashi Keitaro、Saeki Mayumi、Miura Kento、Yamasaki Norimasa、Matsuda Masaya、Shimora Hayato、Nabe Takeshi、Shimizu Yasuo、Fujita Tomoe、Endou Hitoshi、Kaminuma Osamu
- Journal Title
  
  Allergy
  
  Volume: 78 Issue: 10 Pages: 2780-2783
- DOI
  10.1111/all.15798
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K14117, KAKENHI-PROJECT-21K06581, KAKENHI-PROJECT-23K07134, KAKENHI-PROJECT-22H00398
[Journal Article] LAT1-specific inhibitor ameliorates severe autoimmune arthritis in SKG mouse2022
- Author(s)
  Owada Takayoshi、Kurasawa Kazuhiro、Endou Hitoshi、Fujita Tomoe、Anzai Naohiko、Hayashi Keitaro
- Journal Title
  
  International Immunopharmacology
  
  Volume: 109 Pages: 108817-108817
- DOI
  10.1016/j.intimp.2022.108817
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K06581, KAKENHI-PROJECT-21K19348
[Journal Article] Therapeutic Potential for Intractable Asthma by Targeting L-Type Amino Acid Transporter 12022
- Author(s)
  Hayashi Keitaro、Kaminuma Osamu
- Journal Title
  
  Biomolecules
  
  Volume: 12 Issue: 4 Pages: 553-553
- DOI
  10.3390/biom12040553
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08603, KAKENHI-PROJECT-21K06581
[Journal Article] L-type amino acid transporter 1 as a target for inflammatory disease and cancer immunotherapy2022
- Author(s)
  Hayashi K, Anzai N.
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 148 Issue: 1 Pages: 31-40
- DOI
  10.1016/j.jphs.2021.09.006
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H03065, KAKENHI-PROJECT-21K06581, KAKENHI-PROJECT-21K19348
[Journal Article] Effects of 1,5-anhydro-D-glucitol on insulin secretion both in in vitro and ex vivo pancreatic preparations2022
- Author(s)
  Ouchi Motoshi、Morita Asuka、Satoh Keitaro、Kobayashi Shunsuke、Terada Misao、Kon Hiroe、Hayashi Keitaro、Suzuki Tatsuya、Oba Kenzo、Sugihara Hitoshi、Yasutake Masahiro、Anzai Naohiko、Fujita Tomoe
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 149 Issue: 2 Pages: 66-72
- DOI
  10.1016/j.jphs.2022.03.005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K11629, KAKENHI-PROJECT-21K06581, KAKENHI-PROJECT-21K15653, KAKENHI-PROJECT-21H03065, KAKENHI-PROJECT-19K10051
[Journal Article] Clinical Significance of <sup>18</sup>F-fluorodeoxyglucose and Glucose Transporter 1 mRNA in Clear Cell Renal Cell Carcinoma2021
- Author(s)
  BETSUNOH HIRONORI、SAKAMOTO SETSU、KAJI YASUSHI、NUKUI AKINORI、KOBAYASHI MINORU、YASHI MASAHIRO、HAYASHI KEITARO、ANZAI NAOHIKO、KAMAI TAKAO
- Journal Title
  
  Anticancer Research
  
  Volume: 41 Issue: 10 Pages: 5179-5188
- DOI
  10.21873/anticanres.15336
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08603, KAKENHI-PROJECT-21H03065, KAKENHI-PROJECT-21K06581, KAKENHI-PROJECT-21K19348
[Journal Article] L-type amino acid transporter 1 inhibitor suppresses murine Th2 cell-mediated bronchial hyperresponsiveness independently of eosinophil accumulation2021
- Author(s)
  Ito Daiki、Miura Kento、Saeki Mayumi、Yamasaki Norimasa、Ogata Sawako、Koyama Teidai、Hiroi Takachika、Mori Akio、Endou Hitoshi、Hayashi Keitaro、Kaminuma Osamu
- Journal Title
  
  Asia Pacific Allergy
  
  Volume: 11 Issue: 3 Pages: e33-e33
- DOI
  10.5415/apallergy.2021.11.e33
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08603, KAKENHI-PROJECT-19H03145, KAKENHI-PROJECT-21K06581, KAKENHI-PROJECT-21K08486, KAKENHI-PROJECT-19K16017
[Journal Article] Antitumor effect of dimethyl itaconate on thymic carcinoma by targeting LDHA-mTOR axis2021
- Author(s)
  Hayashi Keitaro、Nakazato Yoshimasa、Ouchi Motoshi、Fujita Tomoe、Endou Hitoshi、Chida Masayuki
- Journal Title
  
  Life Sciences
  
  Volume: 282 Pages: 119847-119847
- DOI
  10.1016/j.lfs.2021.119847
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08603, KAKENHI-PROJECT-20K09183, KAKENHI-PROJECT-21K06581
[Journal Article] The Effects of Trypsin Inhibitor on Insulin Secretion Using Rat Pancreas in an Organ Bath2021
- Author(s)
  MORITA ASUKA、OUCHI MOTOSHI、SATOH KEITARO、KOBAYASHI SHUNSUKE、TERADA MISAO、WAKASHIN HIDEFUMI、KON HIROE、HAYASHI KEITARO、ANZAI NAOHIKO、SHIMIZU AKIRA、SUGIHARA HITOSHI、OBA KENZO、FUJITA TOMOE
- Journal Title
  
  In Vivo
  
  Volume: 35 Issue: 5 Pages: 2551-2558
- DOI
  10.21873/invivo.12537
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08603, KAKENHI-PROJECT-19K10051, KAKENHI-PROJECT-20K11629, KAKENHI-PROJECT-21K06581, KAKENHI-PROJECT-21K15653
[Journal Article] L-type amino acid transporter 1 (LAT1)-specific inhibitor is effective against T cell-mediated nasal hyperresponsiveness2020
- Author(s)
  Kaminuma Osamu、Nishimura Tomoe、Saeki Mayumi、Yamasaki Norimasa、Ogata Sawako、Fujita Tomoe、Endou Hitoshi、Hayashi Keitaro
- Journal Title
  
  Allergol. Int.
  
  Volume: 69 Issue: 3 Pages: 455-458
- DOI
  10.1016/j.alit.2019.12.006
- NAID
  130007877710
- ISSN
  1323-8930, 1440-1592
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08603, KAKENHI-PROJECT-18K19561
[Journal Article] Fluvastatin is effective against thymic carcinoma2020
- Author(s)
  Hayashi Keitaro、Nakazato Yoshimasa、Morito Noriaki、Sagi Mizuki、Fujita Tomoe、Anzai Naohiko、Chida Masayuki
- Journal Title
  
  Life Sciences
  
  Volume: 240 Pages: 117110-117110
- DOI
  10.1016/j.lfs.2019.117110
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08603, KAKENHI-PROJECT-17K10810, KAKENHI-PROJECT-20K09183
[Journal Article] Development of an organ bath technique for isolated rat pancreas preparations to assess the effect of 1,5-AG on insulin secretion2020
- Author(s)
  MORITA Asuka、OUCHI Motoshi、SATOH Keitaro、TERADA Misao、KON Hiroe、WAKASHIN Hidefumi、HAYASHI Keitaro、ANZAI Naohiko、OBA Kenzo、SHIMIZU Akira、FUJITA Tomoe
- Journal Title
  
  Exp. Anim.
  
  Volume: 69 Issue: 2 Pages: 127-134
- DOI
  10.1538/expanim.19-0059
- NAID
  130007835069
- ISSN
  0007-5124, 1341-1357, 1881-7122
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08603, KAKENHI-PROJECT-19K10051, KAKENHI-PROJECT-18K15428
[Journal Article] L-type amino acid transporter 1, LAT1, in growth hormone-producing pituitary tumor cells2020
- Author(s)
  Satou Motoyasu、Wang Jason、Nakano-Tateno Tae、Teramachi Mariko、Suzuki Tokiko、Hayashi Keitaro、Lamothe Shawn、Hao Yubin、Kurata Harley、Sugimoto Hiroyuki、Chik Constance、Tateno Toru
- Journal Title
  
  Molecular and Cellular Endocrinology
  
  Volume: 515 Pages: 110868-110868
- DOI
  10.1016/j.mce.2020.110868
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08603, KAKENHI-PROJECT-20K07314
[Journal Article] Imaging of lysophosphatidylcholine in an induced pluripotent stem cell-derived endothelial cell network2020
- Author(s)
  Shimizu Yasuo、Nakamura Yusuke、Horibata Yasuhiro、Fujimaki Mio、Hayashi Keitaro、Uchida Nobuhiko、Morita Hiroko、Arai Ryo、Chibana Kazuyuki、Takemasa Akihiro、Sugimoto Hiroyuki
- Journal Title
  
  Regenerative Therapy
  
  Volume: 14 Pages: 299-305
- DOI
  10.1016/j.reth.2020.03.007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08603, KAKENHI-PROJECT-20K07314
[Journal Article] LAT1‐specific inhibitor is effective against T cell‐mediated allergic skin inflammation2019
- Author(s)
  Hayashi Keitaro、Kaminuma Osamu、Nishimura Tomoe、Saeki Mayumi、Matsuoka Kunie、Hiroi Takachika、Jutabha Promsuk、Iwata Yohei、Sugiura Kazumitsu、Owada Takayoshi、Kurasawa Kazuhiro、Okayasu Isao、Ouchi Motoshi、Fujita Tomoe、Kanai Yoshikatsu、Endou Hitoshi、Anzai Naohiko
- Journal Title
  
  Allergy
  
  Volume: 75 Issue: 2 Pages: 463-467
- DOI
  10.1111/all.14019
- NAID
  40022246112
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08603, KAKENHI-PROJECT-18K08281, KAKENHI-PROJECT-19H03407, KAKENHI-PROJECT-18K19429
[Journal Article] L-Type Amino Acid Transporter 1 Immunoreactivity as a Possible Diagnostic and Prognostic Marker of Thymic Carcinoma2018
- Author(s)
  Maeda Sumiko、Nakazato Yoshimasa、Hayashi Keitaro、Nishihira Morimichi、Inoue Takashi、Araki Osamu、Karube Yoko、Kobayashi Satoru、Chida Masayuki
- Journal Title
  
  Tohoku J. Exp. Med.
  
  Volume: 246 Issue: 3 Pages: 167-174
- DOI
  10.1620/tjem.246.167
- NAID
  130007517206
- ISSN
  0040-8727, 1349-3329
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08603, KAKENHI-PROJECT-17K10810
[Journal Article] Uric acid lowering in relation to HbA1c reductions with the SGLT2 inhibitor tofogliflozin2018
- Author(s)
  Ouchi Motoshi、Oba Kenzo、Kaku Kohei、Suganami Hideki、Yoshida Akihiro、Fukunaka Yasunori、Jutabha Promsuk、Morita Asuka、Otani Naoyuki、Hayashi Keitaro、Fujita Tomoe、Suzuki Tatsuya、Yasutake Masahiro、Anzai Naohiko
- Journal Title
  
  Diabetes, Obesity and Metabolism
  
  Volume: 20 Issue: 4 Pages: 1061-1065
- DOI
  10.1111/dom.13170
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08603
[Journal Article] Effects of uric acid on vascular endothelial function from bedside to bench2018
- Author(s)
  Otani Naoyuki、Toyoda Shigeru、Sakuma Masashi、Hayashi Keitaro、Ouchi Motoshi、Fujita Tomoe、Anzai Naohiko、Tanaka Atsushi、Node Koichi、Uemura Naoto、Inoue Teruo
- Journal Title
  
  Hypertension Research
  
  Volume: 41 Issue: 11 Pages: 923-931
- DOI
  10.1038/s41440-018-0095-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08603, KAKENHI-PROJECT-18K08200
[Journal Article] LAT1 is a central transporter of essential amino acids in human umbilical vein endothelial cell.2014
- Author(s)
  Hayashi K, Jutabha P, Kamai T, Endou H, Anzai N
- Journal Title
  
  J Pharmacol Sci.
  
  Volume: 124 Pages: 511-513
- NAID
  130003391512
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590328
[Journal Article] Role of LAT1 in promotion of amino acid incorporation in activated T cells.2014
- Author(s)
  Hayashi K, Anzai N
- Journal Title
  
  Crit Rev Immunol.
  
  Volume: 34 Pages: 467-479
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24590328
[Journal Article] LAT1 is a critical transporter of essential amino acids for immune reactions in activated human T cells.2013
- Author(s)
  Hayashi K, Jutabha P, et al
- Journal Title
  
  J Immunol.
  
  Volume: 191 Issue: 8 Pages: 4080-4085
- DOI
  10.4049/jimmunol.1300923
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590647, KAKENHI-PROJECT-24590328, KAKENHI-PROJECT-25670600
[Journal Article] c-Myc is crucial for the expression of LAT1 in MIA Paca-2 human pancreatic cancer cells.2012
- Author(s)
  Hayashi, K., Jutabha, P., Endou, H., Anzai, N.
- Journal Title
  
  Oncol. Rep.
  
  Volume: 28 Pages: 537-544
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590328
[Journal Article] c-Myc is crucial for the expression of LAT1 in MIA Paca-2 human pancreatic cancer cells.2012
- Author(s)
  Hayashi K, Jutabha P, et al.
- Journal Title
  
  Oncol Rep
  
  Volume: 28 Issue: 3 Pages: 862-866
- DOI
  10.3892/or.2012.1878
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590647, KAKENHI-PROJECT-23659447
[Journal Article] 高尿酸血症のモデル動物2011
- Author(s)
  安西尚彦、内田幸介、林啓太朗
- Journal Title
  
  内分泌・糖尿病・代謝内科
  
  Volume: 33 Pages: 462-467
- NAID
  40019154794
- Data Source
  KAKENHI-PROJECT-21390073
[Journal Article] A novel human organic anion transporter NPT4 mediates the transport of ochratoxin A2011
- Author(s)
  Jutabha P, Anzai N, Hayashi K, Domae M, Uchida K, Endou H, Sakurai H
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 116 Pages: 392-396
- NAID
  10029895719
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659447
[Patent] 免疫抑制剤2013
- Inventor(s)
  林啓太朗、安西尚彦
- Industrial Property Rights Holder
  ジェイファーマ株式会社
- Industrial Property Rights Type
  特許
- Filing Date
  2013-08-20
- Acquisition Date
  2014-02-14
- Data Source
  KAKENHI-PROJECT-24590328
[Presentation] LAT1特異的阻害薬によるTh17依存的喘息の抑制2023
- Author(s)
  林啓太朗、佐伯真弓、松田将也、奈邉健、神沼修
- Organizer
  Kyoto T Cell Conference
- Data Source
  KAKENHI-PROJECT-21K06581
[Presentation] 目で見る抗がん薬の作用機序～動画の活用～2022
- Author(s)
  林啓太朗, 茂木正樹, 藤田朋恵
- Organizer
  第43回日本臨床薬理学会学術総会
- Data Source
  KAKENHI-PROJECT-21K06581
[Presentation] Th17細胞依存的ステロイド抵抗性喘息モデルに対するアミノ酸トランスポーターLAT1阻害薬の効果2022
- Author(s)
  林啓太朗、佐伯真弓、三浦健人、山崎憲政、尾形佐和子、森晶夫、廣井隆親、遠藤仁、藤田朋恵、神沼修
- Organizer
  第71回日本アレルギー学会学術大会
- Data Source
  KAKENHI-PROJECT-21K06581
[Presentation] T細胞依存性アレルギー性炎症に対するLAT1阻害薬の効果2021
- Author(s)
  神沼修, 佐伯真弓, 西村友枝, 廣井隆親, 三浦健人, 山崎憲政, 尾形佐和子, 伊藤大起, 古山禎大, 森晶夫, 遠藤仁, 安西尚彦, 林啓太朗
- Organizer
  第94回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-17K08603
[Presentation] LAT1特異的阻害薬によるアレルギー性鼻炎の抑制2021
- Author(s)
  林啓太朗、佐伯真弓、西村友枝、尾形佐和子、山崎憲政、遠藤仁、神沼修
- Organizer
  第70回日本アレルギー学会学術大会
- Data Source
  KAKENHI-PROJECT-17K08603
[Presentation] Th17細胞依存的ステロイド抵抗性喘息モデルに対するアミノ酸トランスポーターLAT1阻害薬の効果2021
- Author(s)
  林　啓太朗、佐伯真弓、三浦健人、山崎憲政、尾形佐和子、森　晶夫、廣井隆親、遠藤　仁、神沼　修
- Organizer
  アレルギー・好酸球研究会 2021
- Data Source
  KAKENHI-PROJECT-21K06581
[Presentation] LAT1特異的阻害薬によるアレルギー性鼻炎の抑制2021
- Author(s)
  林啓太朗、佐伯真弓、西村友枝、尾形佐和子、山崎憲政、遠藤仁、神沼修
- Organizer
  第70回日本アレルギー学会学術大会
- Data Source
  KAKENHI-PROJECT-21K06581
[Presentation] Th17細胞依存的ステロイド抵抗性喘息モデルに対するアミノ酸トランスポーターLAT1阻害薬の効果2021
- Author(s)
  林　啓太朗、佐伯真弓、三浦健人、山崎憲政、尾形佐和子、森　晶夫、廣井隆親、遠藤　仁、神沼　修
- Organizer
  アレルギー・好酸球研究会 2021
- Data Source
  KAKENHI-PROJECT-17K08603
[Presentation] Th17細胞依存的ステロイド抵抗性喘息モデルに対するアミノ酸トランスポーターLAT1阻害薬の効果2021
- Author(s)
  林　啓太朗、佐伯真弓、神沼　修
- Organizer
  第95回日本薬理学会学術集会
- Data Source
  KAKENHI-PROJECT-17K08603
[Presentation] Th17細胞依存的ステロイド抵抗性喘息モデルに対するアミノ酸トランスポーターLAT1阻害薬の効果2021
- Author(s)
  林　啓太朗、佐伯真弓、神沼　修
- Organizer
  第95回日本薬理学会学術集会
- Data Source
  KAKENHI-PROJECT-21K06581
[Presentation] Suppressive effects of LAT1-specific inhibitor on T cell-mediated allergic skin inflammation2019
- Author(s)
  林啓太朗、松岡邦枝、神沼修
- Organizer
  第48回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-17K08603
[Presentation] LAT1特異的阻害薬によるアトピー性皮膚炎の抑制効果2019
- Author(s)
  林啓太朗、西村　友枝、佐伯真弓、杉浦一充、岩田洋平、遠藤　仁, 神沼　修
- Organizer
  第47回日本臨床免疫学会総会
- Data Source
  KAKENHI-PROJECT-17K08603
[Presentation] LAT1阻害薬のヒトT細胞活性化およびマウスアトピー性皮膚炎モデルに対する抑制効果2019
- Author(s)
  林啓太朗、神沼修、西村友枝、佐伯真弓、松岡邦枝、杉浦一充、岩田洋平、藤田朋恵、遠藤仁、安西尚彦
- Organizer
  第40回日本臨床薬理学会学術総会
- Data Source
  KAKENHI-PROJECT-17K08603
[Presentation] Role of amino acid transporter LAT1 in T cell activation2018
- Author(s)
  林啓太朗
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-17K08603
[Presentation] Suppressive effects of LAT1 specific inhibitor on allergy disease2018
- Author(s)
  Keitaro Hayashi, Osamu Kaminuma, Tomoe Nishimura, Promsuk Jutabha, Hitoshi Endo,Tomoe Fujita, Naohiko Anzai
- Organizer
  18th World Congress of Basic and Clinical Pharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08603
[Presentation] LAT1特異的阻害薬によるアレルギー性皮膚炎の抑制2018
- Author(s)
  林啓太朗、Jutabhar Pomsuk、神沼修、西村友枝、岩田洋平、杉浦一充、藤田朋恵、金井好克、遠藤仁、安西尚彦
- Organizer
  第92回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-17K08603
[Presentation] LAT1特異的阻害薬によるT細胞誘発性アレルギー性皮膚炎の抑制効果2018
- Author(s)
  林啓太朗
- Organizer
  第28回Kyoto T Cell Conference
- Data Source
  KAKENHI-PROJECT-17K08603
[Presentation] LAT1を標的としたアレルギー疾患における新たな治療戦略の開発2017
- Author(s)
  林啓太朗
- Organizer
  第19回応用薬理シンポジウム
- Data Source
  KAKENHI-PROJECT-17K08603
[Presentation] Expression of L type amino acid transporter 1 is a possible diagnostic and prognostic marker of thymic carcinoma2017
- Author(s)
  Maeda S, Nakazato M, Hayashi R, Ito Y, Nishihira M, Inoue T, Arakai O, Karube Y, Kobayashi S, Chida M.
- Organizer
  International Thymic Malignancy Interest Group 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10810
[Presentation] Na+依存性モノカルボン酸トランスポーター SMCT1と結合PDZタンパク質PDZRN3のタンパク質相互作用の解明2017
- Author(s)
  大塚裕介, 大野雄太, 大谷直由, Jutabha Promsuk, 降幡知巳, 林啓太朗, 大内基司, 鶴岡秀一, 安西尚彦
- Organizer
  第137回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-17K08603
[Presentation] Role of Amino Acid Transporter LAT1 in Activated Human T cell2015
- Author(s)
  Keitaro Hayashi
- Organizer
  The Second Kitasato-Yale Fluid Symposium in Tokyo
- Place of Presentation
  東京
- Year and Date
  2015-12-05
- Data Source
  KAKENHI-PROJECT-26670631
[Presentation] アミノ酸トランスポーターLAT1阻害薬による血管形成阻害2015
- Author(s)
  林啓太朗、Promsuk Jutabha、遠藤仁、安西尚彦
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋
- Year and Date
  2015-03-20
- Data Source
  KAKENHI-PROJECT-24590328
[Presentation] アミノ酸トランスポーターLAT1特異的阻害薬による胸腺癌抑制2015
- Author(s)
  林啓太朗、Jutabha Promsuk、千田雅之、遠藤仁、安西尚彦
- Organizer
  第132回日本薬理学会関東部会
- Place of Presentation
  千葉県浦安
- Year and Date
  2015-07-04
- Data Source
  KAKENHI-PROJECT-26670631
[Presentation] Suppressive Effects of LAT1-Specific Inhibitor on the Activation of Human T Cells.2015
- Author(s)
  Hayashi K, H Anzai.
- Organizer
  13th Cytokines & Inflammation Conference
- Place of Presentation
  San Diego
- Year and Date
  2015-01-29
- Data Source
  KAKENHI-PROJECT-24590328
[Presentation] T細胞におけるアミノ酸トランスポーターLAT1の役割2015
- Author(s)
  林啓太朗
- Organizer
  第92回日本生理学会大会
- Place of Presentation
  神戸
- Year and Date
  2015-03-21
- Invited
- Data Source
  KAKENHI-PROJECT-24590328
[Presentation] 必須アミノ酸トランスポーターLAT1阻害薬の胸腺がんに対する増殖抑制効果2014
- Author(s)
  林啓太朗、Promsuk Jutabha、遠藤仁、安西尚彦
- Organizer
  第73回日本癌学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2014-09-25
- Data Source
  KAKENHI-PROJECT-24590328
[Presentation] 必須アミノ酸トランスポーターLAT1の機能阻害による破骨細胞分化の抑制2014
- Author(s)
  林啓太朗、安西尚彦
- Organizer
  第32回日本骨代謝学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2014-07-04
- Data Source
  KAKENHI-PROJECT-24590328
[Presentation] Induction of expression of LAT1, an essential amino acids transporter, in activated T cells2013
- Author(s)
  林啓太朗、Promsuk Jutabha、遠藤仁、安西尚彦
- Organizer
  米国免疫学会年会
- Place of Presentation
  ホノルル（米国）
- Data Source
  KAKENHI-PROJECT-24590328
[Presentation] 腎尿酸トランスポーター遺伝子改変マウスを用いた高尿酸血症発症機序の解明2011
- Author(s)
  安西尚彦、木村徹^1(^1 杏林大・医)
- Organizer
  第54回日本腎臓学会学術総会ワークショップ1 腎疾患・病態の理解を目指すトランスポーター遺伝子改変動物の利用
- Place of Presentation
  横浜
- Year and Date
  2011-06-15
- Data Source
  KAKENHI-PROJECT-21390073
[Presentation] Suppressive effects of LAT1-specific inhibitor on the activation of human T cells
- Author(s)
  林啓太朗、安西尚彦
- Organizer
  第7回次世代を担う医療薬科学シンポジウム（日本薬学会）
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-24590328
[Presentation] ヒトスキルス胃癌におけるLAT1発現減少による遺伝子変化の解析
- Author(s)
  林啓太朗、遠藤仁、安西尚彦
- Organizer
  日本薬理学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24590328
[Presentation] 癌胎児性中性アミノ酸トランスポーターLAT1特異的阻害薬によるT細胞活性化の抑制
- Author(s)
  林啓太朗、Promsuk Jutabha、遠藤仁、安西尚彦
- Organizer
  第129回　日本薬理学会関東部会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24590328
[Presentation] 癌胎児性中性アミノ酸トランスポーターLAT1の発現低下に伴う癌細胞の遺伝子発現変化
- Author(s)
  林啓太朗、遠藤仁、安西尚彦
- Organizer
  日本がん分子標的治療学会学術集会
- Place of Presentation
  北九州市
- Data Source
  KAKENHI-PROJECT-24590328
[Presentation] T細胞活性化における必須アミノ酸トランスポーターLAT1の重要性
- Author(s)
  林啓太朗、Promsuk Jutabha、遠藤仁、安西尚彦
- Organizer
  第10回　宮崎サイエンスキャンプ
- Place of Presentation
  宮崎
- Data Source
  KAKENHI-PROJECT-24590328
[Presentation] 必須アミノ酸トランスポーターLAT1の特異的阻害薬によるヒトT細胞の活性化抑制
- Author(s)
  林啓太朗、Promsuk Jutabha、遠藤仁、安西尚彦
- Organizer
  第124回　日本薬理学会総会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-24590328
[Presentation] スキルス胃癌細胞44As3－11におけるLAT1の発現現象による遺伝子発現変化の解析
- Author(s)
  林啓太朗、遠藤仁、安西尚彦
- Organizer
  日本癌学会学術集会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24590328
[Presentation] LAT1特異的阻害薬によるT細胞活性化の抑制
- Author(s)
  林啓太朗、遠藤仁、安西尚彦
- Organizer
  第41回日本臨床免疫学会総会
- Place of Presentation
  下関
- Data Source
  KAKENHI-PROJECT-24590328

1. CHIDA MASAYUKI (70333812)

# of Collaborated Projects: 4 results

# of Collaborated Products: 2 results
2. ANZAI Naohiko (70276054)

# of Collaborated Projects: 3 results

# of Collaborated Products: 22 results
3. JUTABHA Promsuk (90541748)

# of Collaborated Projects: 3 results

# of Collaborated Products: 16 results
4. 倉沢和宏 (30282479)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
5. KOJIMA Shuichi (60178267)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. ENDOU Hitoshi

# of Collaborated Projects: 2 results

# of Collaborated Products: 12 results
7. UCHIDA Kohsuke (30168695)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. DOMAE Mariko (20285878)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. YAN Kunimasa (70255389)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. KIMURA Toru (30433725)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. FUKUTOMI Toshiyuki (30439187)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. MIURA Daisaku (60510873)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. KANAI Yoshikatsu (60204533)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. KAWAHARA Katsumasa (70134525)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. TSUKADA Ai

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. WEMPE Michael F.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. AMMONPATUMRAT Sirirat

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. THAMMAPRATIP Thanapol

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 三浦健人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 佐藤慶太郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 大内基司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 森田亜州華

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

hayashi keitaro 林 啓太朗

Hayashi Keitaro 林 啓太朗

HAYASHI Keitaro 林 啓太朗

Research Projects

Research Products

Co-Researchers

LAT1-EWSR1 axisを標的とした新たな免疫疾患治療戦略の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

HMGCR-MAPK7 axisを標的とした新たな胸腺癌治療戦略の開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

LAT1によるアルギニンメチル化調節を介した新規T細胞活性化機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

HMG-CoA還元酵素を標的とした胸腺癌に対する新たな治療戦略の構築

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Suppressive effects of LAT1-specific inhibitor on osteoclastgenesisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of new therapeutic strategies for thymic carcinoma targeting LAT1

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Strategy for epithelial thymic malignancy treatment focusing on L-type amino acid transporter 1

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Role of LAT1 in T cell activationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Novel regulatory mechanism of renaltubular transporter function by SUMOylation-deSUMOylation

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

New drug development for hyperuricemia targeting novel urate efflux transporter URATv1

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] ハートナップ病、別冊日本臨床 新領域別症候群シリーズNo. 20 先天性代謝異常症候群(第2版)2012

Author(s)

Data Source

[Journal Article] Hamster Sperm Possess Functional Na+/Ca2+-Exchanger 1: Its Implication in Hyperactivation2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] JPH203, a LAT1 inhibitor, alleviates steroid‐resistant murine airway inflammation mediated by Th17 cells2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] LAT1-specific inhibitor ameliorates severe autoimmune arthritis in SKG mouse2022

hayashi keitaro 林啓太朗

Hayashi Keitaro 林啓太朗

HAYASHI Keitaro 林啓太朗

[Book] ハートナップ病、別冊日本臨床新領域別症候群シリーズNo. 20 先天性代謝異常症候群(第2版)2012