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Uehara Tomoya  上原 知也

… Alternative Names

UEHARA Tomoya  上原 知也

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Researcher Number 10323403
Other IDs
  • ORCIDhttps://orcid.org/0000-0002-1140-9800
External Links
Affiliation (Current) 2025: 千葉大学, 大学院薬学研究院, 教授
Affiliation (based on the past Project Information) *help 2019 – 2024: 千葉大学, 大学院薬学研究院, 教授
2016 – 2018: 千葉大学, 大学院薬学研究院, 准教授
2012 – 2015: 千葉大学, 薬学研究科(研究院), 准教授
2012: 千葉大学, 大学院・薬学研究院, 准教授
2012: 千葉大学, 薬学研究院, 准教授 … More
2011: 千葉大学, 薬学研究科(研究院), 講師
2008 – 2010: Chiba University, 大学院・薬学研究院, 講師
2008: Chiba University, 大学院薬学研究院, 講師
2007: Chiba University, GRADUATE SCHOOL OF PHARMACEUTICAL SCIENCES, ASSISTANT PROFESSOR
2006: CHIBA UNIVERSITY, GRADUATE SCHOOL OF PHARMATICAL SCIENCE, ASSISTANT PROFESSOR, 大学院薬学研究院, 助手
2001 – 2006: 千葉大学, 大学院・薬学研究院, 助手
2000: 千葉大学, 薬学部, 助手 Less
Review Section/Research Field
Principal Investigator
Radiation science / Basic Section 52040:Radiological sciences-related / 医薬分子機能学
Except Principal Investigator
Radiation science / Basic Section 52040:Radiological sciences-related / Radiation science / Digestive surgery / Basic Section 56030:Urology-related / Medium-sized Section 15:Particle-, nuclear-, astro-physics, and related fields
Keywords
Principal Investigator
SPECT / 核医学治療薬剤 / 核医学治療 / 腎臓 / PET / 治療効果判定 / 放射性医薬品 / 内用放射線治療 / ラジオセラノスティクス / PSMA … More / セラノスティクス / 前立腺がん / radiotheranostics / 核医学イメージング / 核医学診断薬剤 / プレターゲティング / 核医学診断 / がん免疫 / 制御性T細胞 / 癌 / 免疫学 / 放射線 / Treg抗体 / Treg細胞 / Treg / イメージング / センチネルリンパ節 / 蛍光 / 内照射治療 / ガリウム / 標識薬剤 / 治療 / オリゴアスパラギン酸 / D-penicillamine / 画像診断 / 放射性ヨウ素 / DNAA-PK / 修復酵素 / DNA二重鎖切断 / 放射線治療 / 核医学画像診断 / メチオニン / MeAIB / アミノ酸輸送システムA / トランスポータ / アミノ酸 / 代謝 / 核移行性 / リソソーム代謝 / 蛋白質標識薬剤 / 核移行性ペプチド … More
Except Principal Investigator
放射性医薬品 / アイソトープ治療 / テクネチウム-99m / 多価効果 / 分子イメージング / 放射性ヨウ素 / 抗体 / 腎障害 / 核医学 / 核医学治療 / セラノスティクス / アスタチン / 体内動態 / 癌 / センチネルリンパ節 / SPECT / 刷子縁膜酵素 / 代謝性スペーサ / 低分子化抗体 / ペプチド / 抗腫瘍ペプチド / 抗腫瘍抗体 / 内用放射線治療 / 放射性レニウム / インテグリン / 代謝性リンカー / 神経内分泌前立腺癌 / 去勢抵抗性前立腺癌 / エクソソーム / 致死性前立腺癌 / アミノ酸トランスポーター / 放射性代謝物 / 負電荷 / 多価ペプチド / アルブミンバインダー / ソマトスタチン / アルファ線 / アスタチン-211 / PET / 繊維芽細胞活性化タンパク質 / 放射性ハロゲン / RI製造 / 二重標識 / 合金 / 原子核反応 / ラジオアイソトープ / 液体金属 / がん治療 / アルファビーム / ビスマス / reticuloendothelial cells / Mannose binding lectins / semiconductor gamma camera / sentinel lymph node / cancer / 網内系細胞親和性トレーサ / 網内系細胞 / マンノース結合分子 / 半導体型ガンマカメラ / ANTIBODY / GENETIC ENGINEERING / EXTRACELLUAR MATRIX / REMODELING / DIAGNOSTIC IMAGING / 遺伝子工学 / 細胞外マトリクス / 組織再構築 / 画像診断学 / peptides / metabolizable linkage / brush border membrane / kidney / radioiodine / antibody fragment / Radiotherapy / 腫瘍内滞留性 / 腫瘍親和性ペプチド / カルボキシペプチダーゼ / 癌治療 / 腎臓 / Serum protein binding / Kinetics regulation / Melanin biosynthesis / Melanoma / Metabolic activity / Internal radiation therapy / Radioipharmaceuticals / Radioiodine / ヨウ素標識アミノ酸 / メラニン形成 / 放射性ヨウ素標識薬剤 / 含硫アミン誘導体 / 含流アミン誘導体 / チロシナーゼ / メラニン生合成 / 悪性黒色腫 / ヨウ素標識薬剤 / 癌の内部照射治療 / 腫瘍特異的代謝亢進 / 放射性医薬品・造影剤 / アポトーシス / キャリアタンパク質 / 比放射能 / トランスポーターイメージング / 人工アミノ酸 / 放射性標識抗体 / 腫瘍細胞 / 血液脳関門 / モノクロナル抗体 / ポリクリロナル抗体 / 中性アミノ酸トランスポーター / 造影剤 / 腫瘍 / 抗体フラグメント / 極微量 / 超高比放射能 / 標識抗体 / 分光解析 / 色素 / 外科 / 胃十二指腸外科学 / 結合力 / 標識プローブ / 混合配位子錯体 / イットリム-90 / 代謝開烈性スペーサ / レニウム-186,188 / インジウムーll1 / イットリウム-90 / インジウム-111 / 代謝開列性スペーサ / カルボキシペプチダーゼM / 腎臓刷子縁膜酵素 / 腎集積 / テクネチウム / 疼痛緩和 / 転移性骨腫瘍 / 骨代謝機能 / ビスフォスフォン酸 Less
  • Research Projects

    (29 results)
  • Research Products

    (87 results)
  • Co-Researchers

    (46 People)
  •  A Comprehensive Amino Acid Transporter-Based Therapeutic Strategy for Lethal Prostate Cancer

    • Principal Investigator
      坂本 信一
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 56030:Urology-related
    • Research Institution
      Chiba University
  •  ラジオハロゲン元素を用いた前立腺がんに対するラジオセラノスティクス薬剤の開発Principal Investigator

    • Principal Investigator
      上原 知也
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52040:Radiological sciences-related
    • Research Institution
      Chiba University
  •  Developing a Curative Therapy for Cancer Stroma Alterations in Pancreatic Cancer and Other Intractable Solid Tumors

    • Principal Investigator
      辻 厚至
    • Project Period (FY)
      2023 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52040:Radiological sciences-related
    • Research Institution
      National Institutes for Quantum Science and Technology
  •  繊維芽細胞活性化タンパク質を標的としたアスタチン-211標識薬剤の開発

    • Principal Investigator
      鈴木 弘行
    • Project Period (FY)
      2022 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52040:Radiological sciences-related
    • Research Institution
      Chiba University
  •  セラノスティクスを目的とした放射性標識ソマトスタチンアナログの体内動態の最適化

    • Principal Investigator
      秋澤 宏行
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52040:Radiological sciences-related
    • Research Institution
      Showa Pharmaceutical University
  •  多価効果と代謝性リンカーの融合による革新的核医学治療薬の開発

    • Principal Investigator
      水野 雄貴
    • Project Period (FY)
      2022 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52040:Radiological sciences-related
    • Research Institution
      Hokkaido University
  •  New design of radiotheranostic agents that reduce renal radioactivityPrincipal Investigator

    • Principal Investigator
      Uehara Tomoya
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52040:Radiological sciences-related
    • Research Institution
      Chiba University
  •  Development of liquid alloy target system for simultaneous radioisotopes production and labeling

    • Principal Investigator
      ishioka noriko
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 15:Particle-, nuclear-, astro-physics, and related fields
    • Research Institution
      National Institutes for Quantum Science and Technology
  •  Development of radiotheranostics agent using Fab fragment of anti-regulatory T cellsPrincipal Investigator

    • Principal Investigator
      Uehara Tomoya
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Radiation science
    • Research Institution
      Chiba University
  •  Development of highly-sensitive apoptosis imaging agent based on new drug design

    • Principal Investigator
      Hanaoka Hirofumi
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Radiation science
    • Research Institution
      Gunma University
  •  Development of dual-modality SPECT/fluorescent probePrincipal Investigator

    • Principal Investigator
      Uehara Tomoya
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Radiation science
    • Research Institution
      Chiba University
  •  Engineering radiolabeled antibody fragments for enhanced tumor to kidney ratioPrincipal Investigator

    • Principal Investigator
      Uehara Tomoya
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Young Scientists (A)
    • Research Field
      Radiation science
    • Research Institution
      Chiba University
  •  99mTc-labeled probes imitating antibodies

    • Principal Investigator
      ARANO Yasushi
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Radiation science
    • Research Institution
      Chiba University
  •  Development of radiolabeled antibody for channel transporter imaging

    • Principal Investigator
      SHIMAMOTO Naoto
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Radiation science
    • Research Institution
      Ibaraki Prefectural University of Health Science
  •  Design of ^<99m>Tc-labled compound for diagnosis of metastatic tumor in bonePrincipal Investigator

    • Principal Investigator
      上原 知也
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Radiation science
    • Research Institution
      Chiba University
  •  がん集積の向上を目指す標識抗体の新規設計法

    • Principal Investigator
      荒野 泰
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Radiation science
    • Research Institution
      Chiba University
  •  Near infrared imaging of indocyanine green for sentinel lymph node navigation using nano-sized particle

    • Principal Investigator
      HAYASHI Hideki
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Chiba University
  •  In vivo imaging of DNA repair for estimating the sensitivity of tumor to radiotherapyPrincipal Investigator

    • Principal Investigator
      UEHARA Tomoya
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Radiation science
    • Research Institution
      Chiba University
  •  Chemical design of chelating agents suitable to radiotherapy using antibody fragments as vehicles

    • Principal Investigator
      YASUSHI Arano
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Radiation science
    • Research Institution
      Chiba University
  •  標的分子との高い結合力を有する多価テクネチウム標識薬剤の設計

    • Principal Investigator
      荒野 泰
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Radiation science
    • Research Institution
      Chiba University
  •  エネルギー依存性アミノ酸輸送システム評価薬剤は癌治療効果の早期判定に有効かPrincipal Investigator

    • Principal Investigator
      上原 知也
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Radiation science
    • Research Institution
      Chiba University
  •  DEMELOPMENT OF RAKIOLABELED SMALLER ANTI-TENASCIN-CANTIBODY FOR CLINICAL USE

    • Principal Investigator
      IRIE Toshiaki
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Radiation science
    • Research Institution
      National Institute of Radiological Sciences
  •  Sentinel lymph node mapping using 99m Tc-labeled mannosyl-neoglycoalbumin and small semiconductor gamma camera for gastrointestinal cancers.

    • Principal Investigator
      HAYASHI Hideki
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Chiba University
  •  アイソトープ治療の副作用低減と治療効果増強を目的とした金属RI標識ペプチドの設計

    • Principal Investigator
      荒野 泰
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Radiation science
    • Research Institution
      Chiba University
  •  癌治療効果の早期判定を目的とする放射性薬剤の開発Principal Investigator

    • Principal Investigator
      上原 知也
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Radiation science
    • Research Institution
      Chiba University
  •  Molecular design of radioiodinated peptides for targeted radiotherapy

    • Principal Investigator
      ARANO Yasushi
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Radiation science
    • Research Institution
      Chiba University
  •  放射能の核移行を目的としたタンパク質標識試薬の開発Principal Investigator

    • Principal Investigator
      上原 知也
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      医薬分子機能学
    • Research Institution
      Chiba University
  •  骨代謝機能診断および転移性骨腫瘍の疼痛緩和を目的とする放射性薬剤の設計

    • Principal Investigator
      YASUSHI Arano
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Radiation science
    • Research Institution
      Chiba University
  •  DEVELOPEMENT OF RADIOIODINATED RADIOPHARMACEUTICALS FOR INTERNAL RADIATION THERAPY OF TUMOR BASED ON ITS SPECIFIC METABOLIC ACTIVITY

    • Principal Investigator
      KAWAI Keiichi
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Radiation science
    • Research Institution
      Kanazawa University
      宮崎医科大学

All 2024 2023 2019 2016 2015 2014 2013 2012 2010 2009 2008 2007 2006 2005 2003 Other

All Journal Article Presentation Book Patent

  • [Book] Technetium-99m Radiopharmaceuticals for lymphoscintigraphy. In : Technetium-99m Radiopharmaceuticals : Status and Trends.2009

    • Author(s)
      Uehara T, Akizawa H, Arano Y.
    • Total Pages
      360
    • Publisher
      Sales and promotion Section, International Atomic Energy Agency
    • Data Source
      KAKENHI-PROJECT-20659186
  • [Book] Technetium-99m radiopharmaceuticals for monitoring drug resistance. In : Technetium-99m Radiopharmaceuticals : Status and Trends.2009

    • Author(s)
      Akizawa H, Uehara T, Arano Y.
    • Total Pages
      360
    • Publisher
      Sales and promotion Section, International Atomic Energy Agency
    • Data Source
      KAKENHI-PROJECT-20659186
  • [Journal Article] 67/68Ga-labeling Agent that Liberates 67/68Ga-NOTA-methionine by Lysosomal Proteolysiso of Parental Low Molecular Weight Polypeptides to Reduce Renal Radioactivity Levels2014

    • Author(s)
      Tomoya Uehara, Takemi Rokugawa, Mai Kinoshita, Aouki Nemoto, Guerra Gomez Fransisco Lazaro, Hirofumi Hanaoka, and Yasushi Arano
    • Journal Title

      Bioconjugate Chem.

      Volume: 25 Issue: 11 Pages: 2038-2045

    • DOI

      10.1021/bc5004058

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25713045
  • [Journal Article] γ-Glutamyl PAMAM dendrimer as versatile precursor for dendrimer-based targeting devices.2010

    • Author(s)
      Uehara T, Ishii D, Uemura T, Suzuki H, Kanei T, et al.
    • Journal Title

      Bioconjugate Chemistry 20

      Pages: 169-174

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20659186
  • [Journal Article] Intracellular reactions affecting 2-amino-4-([^<11>C] methylthio) butyric acid ([^<11>C] methionine) response to carbon ion radiotherapy in C10 glioma cells.2009

    • Author(s)
      Uehara T, Nakagawa M, Takai N, Koike S., et al.
    • Journal Title

      Nuclear Medicine and Biology 36

      Pages: 985-991

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20659186
  • [Journal Article] Assessment of macrocyclic triamine ligands as synthons for organometalic(99m)Tc radiopharmaceuticals.2008

    • Author(s)
      Suzuki K, Shimmura N, Thipyapong K, Uehara T, Aldzawa H, Arano Y.
    • Journal Title

      Inorg Chem. 47

      Pages: 2593-600

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390342
  • [Journal Article] Assessment of macrocyclic triamine ligands as syntons for organo-metallic <99m>^Tc radiopharmaceuticals2008

    • Author(s)
      K. Suzuki, N. SHimmura, T. Uehara, H. Akizawa, Y. Arano
    • Journal Title

      Inorg Chem 47

      Pages: 2593-2600

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390328
  • [Journal Article] Renal uptake and metabolism of radiopharmaceuticals Derived from peptides and proteins2008

    • Author(s)
      Akizawa H, Uehara T, Arano Y.
    • Journal Title

      Advanced Drug Delivery Reveiws 60

      Pages: 1319-1328

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20659186
  • [Journal Article] Assessment of macrocyclic triamine ligands as syntons for organometallic ^<99m>Tc radiopharmaceuticals2008

    • Author(s)
      Suzuki K, Shimmura T, Thipyapong K, Uehara T, Akizawa H, Arano Y.
    • Journal Title

      Inorg. Chem. 47

      Pages: 2593-2600

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390328
  • [Journal Article] Noninvasive detection of cardiac repair after acute myocardial infarction in rats by 111In-Fab fragment of monoclonal antibody specific for tenascin-C.2008

    • Author(s)
      Odaka K, Uehara T, Arano Y, Adachi S, Tadokoro H, Yoshida K, Hasegawa H, I manaka-Yoshida K, Yoshida T, Hiroe M, Irie T, Komuro I.
    • Journal Title

      Int. Heart Journal 49

      Pages: 481-492

    • NAID

      130000069081

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390328
  • [Journal Article] Komuro I. Noninvasive detection of cardiac repair after acute myocardial infarction in rats by ^<111>In Fab fragment of monoclonal antibody specific for tenascin-C.2008

    • Author(s)
      Odaka K, Uehara T, Arano Y, Adachi S, Tadokoro H, Yoshida K, Hasegawa H, Imanaka-Yoshida K, Yoshida T, Hiroe M, Irie T, Tanada S.
    • Journal Title

      Int. Heart J. 49

      Pages: 481-492

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390328
  • [Journal Article] Assessment of macrocyclic triamine ligands as syntons for organometallic 99mTc radiopharmaceuticals.2008

    • Author(s)
      Suzuki K, Shimmura N, Thipyapong K, Uehara T, Akizawa H, Arano Y.
    • Journal Title

      Inorg Chem 47

      Pages: 2593-2600

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390328
  • [Journal Article] Assessment of macrocyclic triamine ligands as synthons for organometallic 99m Tcradiopharmaceuticals.2008

    • Author(s)
      Suzuki K, Shimmura N, Thipyapong K, Uehara T, Akizawa H, Arano Y.
    • Journal Title

      Inorg Chem 47

      Pages: 2593-2600

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390342
  • [Journal Article] Assessment of macrocyclic triamine ligands as synthons for organometallic (99m)Tc radiopharmaceuticals.2008

    • Author(s)
      Suzuki K, Shimmura N, Thipyapong K, Uehara T, Akizawa H, Arano Y.
    • Journal Title

      Inorg Chem. 47

      Pages: 2593-600

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390342
  • [Journal Article] Assessment of macrocyclic triamine ligands as syntons for organo-metallic ^<99m>Tc radiopharmaceuticals2008

    • Author(s)
      K. Suzuki, N. SHimmura, T. Uehara, H. Akizawa, Y. Arano
    • Journal Title

      Inorg Chem 47

      Pages: 2593-2600

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18659342
  • [Journal Article] Renal metabolism of radiopharmaceuticals derived from peptides and proteins2008

    • Author(s)
      Akizawa H, Uehara T, Arano Y
    • Journal Title

      Adv. Drug Deliv. Reviews 60

      Pages: 1319-1328

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390328
  • [Journal Article] Renal uptake and metabolism of radiopharma- ceuticals derived from peptides and proteins.2008

    • Author(s)
      Akizawa H, Uehara T, Arano Y.
    • Journal Title

      Adv. Drug Deliv. Review 60

      Pages: 1319-1328

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390328
  • [Journal Article] Noninvasive detection of cardiac repair after acute myo cardial infarction in rats by 111In?Fab fragment of mon oclonal antibody specific for tenascin-C.2008

    • Author(s)
      Odaka K, Uehara T, Arano Y Adachi S, Yadokoro H, Yoshida K, Hasegawa H, I manaka-Yoshida K, Yoshida T, Hiroe M, Irie T, Tanada S, Komuro I.
    • Journal Title

      International Heart Journal 49

      Pages: 481-492

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20659186
  • [Journal Article] Technetium-99m-labeled long chain fatty acid analogs metabolized by β-oxidation in the heart.2007

    • Author(s)
      T.Uehara, T.Uemura, S.Hirabayashi, S.Adachi, K.Odaka, H.Akizawa, Y.Magata, T.Irie, Y.Arano
    • Journal Title

      Journal of Medicinal Chemistry 50(3)

      Pages: 543-249

    • Data Source
      KAKENHI-PROJECT-18659342
  • [Journal Article] Design, synthesis and evaluation of [^<186>Re]organorhenium-labeled antibody fragments with renal enzyme-cleavable linkage for low renal radioactivity levels.2007

    • Author(s)
      T.Uehara, M.Koike, H.Nakata, H.Hanaoka, Y.Iida, K.Hashimoto, H.Akizawa, K.Endo, Y.Arano
    • Journal Title

      Bioconjugate Chemistry 18(1)

      Pages: 190-198

    • Data Source
      KAKENHI-PROJECT-18659342
  • [Journal Article] Assessment of ^186Re-chelate-conjegated bisphosphonate for the development of new rradiopharmaceuticals for bone.2007

    • Author(s)
      T.Uehara, Z-L.Jin, K.Ogawa, H.Akizawa, K.Hashimoto, M.Nakayama, Y.Arano.
    • Journal Title

      Nuclear Mesicine and Biology 34(1)

      Pages: 79-87

    • Data Source
      KAKENHI-PROJECT-18390328
  • [Journal Article] Technetium-99m-labeled long fatty acid analogues metabolized by beta-oxidation in the heart.2007

    • Author(s)
      Uehara T, Uemura T, Hirabayashi S, Adachi S, Odaka K, Akizawa H, Magata Y, Irie T, Arano Y.
    • Journal Title

      J Med Chem. 50

      Pages: 543-9

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390342
  • [Journal Article] 臨床応用に向けたラジオアイソトープ標識坑テネイシンC低分子化抗体の開発:抗体2種類の同時静注による検討2007

    • Author(s)
      小高 謙一, 上原 知也, 小林 典裕, 今中 恭子, 荒野 泰, 棚田 修二, 入江 俊章
    • Journal Title

      インナービジョン 22

      Pages: 21-21

    • Data Source
      KAKENHI-PROJECT-17390342
  • [Journal Article] Technetium-99m-labeled long chain fatty acid analogues metabolized by beta-oxidation in the heart.2007

    • Author(s)
      Uehara T, Uemura T, Hirabayashi S, Adachi S, Odaka K, Akizawa H, Magata Y, Irie T, Arano Y.
    • Journal Title

      J Med Chem 50

      Pages: 543-549

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390342
  • [Journal Article] Technetium-99m-labeled long chain fatty acid analogs metabolized by β-oxidation in the heart2007

    • Author(s)
      Uehara T, Uemura T, Hirabayashi S, Adachi S, Odaka K, Akizawa H, Magata Y, Irie T, Arano Y.
    • Journal Title

      J. Med. Chem. 50

      Pages: 543-549

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390328
  • [Journal Article] 臨床応用に向けたラジオアイソトープ標識坑テネイシンC低分子化抗体の開発 : 抗体2種類の同時静注による検討2007

    • Author(s)
      小高謙一,上原知也,小林典裕,今中恭子,荒野泰,棚田修二,入江俊章
    • Journal Title

      インナービジョン 22

      Pages: 21-21

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390342
  • [Journal Article] Development of radiolabeled smaller anti-tenascin-C antibody for clinical use : comparison between two antibodies by dual injection.2007

    • Author(s)
      odaka K, Uehara T, Kobayashi N, Imanaka-Yoshida K, Arano Y, Tanada S, Irie T.
    • Journal Title

      Innervision. 22

      Pages: 21-21

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390342
  • [Journal Article] Techonetium-99m-labeled long chain fatty acid analogs metabolized by β-oxidation in the heart.2007

    • Author(s)
      T.Uehara, T.Uemura, S.Hirabayashi, S.Adachi, K.Odaka, H.Akizawa, Y.Magata, T, Irie, Y.Arano.
    • Journal Title

      Journal of Medicinal Chemistry 50(3)

      Pages: 543-249

    • Data Source
      KAKENHI-PROJECT-18390328
  • [Journal Article] Design, synthesis and evaluation of [186Re]organorhenium-labeled antibody frag- ments with renal enzyme-cleavable linkage for low renal radioactivity levels2007

    • Author(s)
      Uehara T, Koike M, Nakata H, Hanaoka H, K, Iida Y, Hashimoto K, Akizawa H, Endo K, Arano Y.
    • Journal Title

      Bioconjugate Chem. 18

      Pages: 190-198

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390328
  • [Journal Article] Assessment of ^<186>Re-chelate-conjugated bisphosphonate for the development of new radiopharmaceuticals for bone.2007

    • Author(s)
      T.Uehara, Z-L.Jin, K.Ogawa, H.Akizawa, K.Hashimoto, M.Nakayama, Y.Arano
    • Journal Title

      Nuclear Medicine and Biology 34(1)

      Pages: 79-87

    • Data Source
      KAKENHI-PROJECT-18659342
  • [Journal Article] Design, synthesis and evaluation of [^186Re]organorhenium-labeled antibody fragments with renal enzyme-cleavble linkage for low renal redioactivity levels.2007

    • Author(s)
      T.Uehara, M.Koike, H.Nakata, H.Hanaoka, Y.Iida, K.Hashimoto, H.Akizawa, K.Endo, Y.Arano.
    • Journal Title

      Bioconjugate Chemistry 18(1)

      Pages: 190-198

    • Data Source
      KAKENHI-PROJECT-18390328
  • [Journal Article] Rhenium-186-monoamimnemonoamidedithiol-conjugated bisphosphonate derivatives for bone pain palliation.2006

    • Author(s)
      K.Ogawa, T.Mukai, Y.Arano, A.Otaka, M.Ueda, T.Uehara, Y.Magata, K.Hashimoto, H.Saji
    • Journal Title

      Nuclear Medicine and Biology 33(4)

      Pages: 513-520

    • Data Source
      KAKENHI-PROJECT-18659342
  • [Journal Article] Rhejum-186-monoamimnemonoamidedithiol-conjugated bisphosphonate dervatives for bone pain palliation.2006

    • Author(s)
      K.Ogawa, T.Mukai, Y.Arano, A.Otaka, M.Ueda, T.Uehara, Y.Magata., K.Hashimoto, H.Saji.
    • Journal Title

      Nuclear Medicine and Biology 33(4)

      Pages: 513-520

    • Data Source
      KAKENHI-PROJECT-18390328
  • [Journal Article] 医薬品開発における放射性薬剤の利用 : 極微量(microdose)投与後の薬物動態のAMSおよびPETによる評価2005

    • Author(s)
      上原 知也, 荒野 泰
    • Journal Title

      日本薬理学会誌 126

      Pages: 129-134

    • NAID

      10019596398

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14370270
  • [Journal Article] Application of radiopharmaceuticals for drug development : Estimation of pharmacokinetics by AMS and PET after microdose administration2005

    • Author(s)
      Tomoya Uehara, Yasushi Arano
    • Journal Title

      Folia Pharmacol.Jpn 126

      Pages: 129-134

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370270
  • [Patent] 放射性標識薬剤2016

    • Inventor(s)
      荒野泰 上原知也
    • Industrial Property Rights Holder
      荒野泰 上原知也
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2016-038836
    • Filing Date
      2016-03-01
    • Data Source
      KAKENHI-PROJECT-25713045
  • [Patent] 核医学診断装置の制御方法、核医学診断装置、診断剤キット、および標識抗テネイシンCscFvフラグメント2012

    • Inventor(s)
      小高謙一、入江俊章、福村利光、田所裕之、小室一成、荒野泰、上原知也、秋澤宏行、小林典裕、吉田利通、吉田恭子、廣江道昭
    • Industrial Property Rights Holder
      独立行政法人放射線医学総合研究所、国立大学法人千葉大学、小林典弘、国立大学法人三重大学、独立行政法人国立国際医療研究センター
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2012-102732
    • Filing Date
      2012-04-27
    • Data Source
      KAKENHI-PROJECT-17390342
  • [Patent] 放射性標識化合物2009

    • Inventor(s)
      荒野泰, 上原知也
    • Filing Date
      2009-04-28
    • Overseas
    • Data Source
      KAKENHI-PROJECT-18390328
  • [Patent] 放射性標識薬剤2008

    • Inventor(s)
      荒野泰、上原知也
    • Industrial Property Rights Holder
      国立大学法人千葉大学
    • Industrial Property Number
      2008-278563
    • Filing Date
      2008-10-29
    • Data Source
      KAKENHI-PROJECT-20659186
  • [Patent] 放射性標識薬剤2008

    • Inventor(s)
      荒野泰、上原知也
    • Industrial Property Rights Holder
      国立大学法人千葉大学
    • Industrial Property Number
      2008-278563
    • Filing Date
      2008-10-29
    • Data Source
      KAKENHI-PROJECT-18390328
  • [Patent] 放射性標識化合物2008

    • Inventor(s)
      荒野泰, 上原知也
    • Industrial Property Rights Holder
      国立大学法人千葉大学
    • Industrial Property Number
      2008-278563
    • Filing Date
      2008-10-29
    • Data Source
      KAKENHI-PROJECT-18390328
  • [Patent] 放射性標識薬剤2007

    • Inventor(s)
      荒野 泰, 上原 知也
    • Industrial Property Rights Holder
      国立大学法人千葉大学
    • Filing Date
      2007-10-29
    • Data Source
      KAKENHI-PROJECT-18390328
  • [Patent] Radioactive metal-cyclopentadieny carbonyl derivatives for disease diagnosis and treatment.2003

    • Inventor(s)
      Arano Y., Uehara T., et al.
    • Industrial Property Rights Holder
      日本メジフィジックス(株)
    • Filing Date
      2003-07-30
    • Acquisition Date
      2005-02-24
    • Data Source
      KAKENHI-PROJECT-14370270
  • [Patent] Radioactive metal-cyclopentadieny carbonyl derivatives for disease diagnosis and treatment.2003

    • Inventor(s)
      Arano Y., Uehara T., et al.
    • Industrial Property Rights Holder
      日本メジフィジックス(株)
    • Filing Date
      2003-07-30
    • Acquisition Date
      2005-02-24
    • Data Source
      KAKENHI-PROJECT-15659277
  • [Presentation] 腎臓への放射能集積の低減を目的とした211At標識PSMA誘導体の開発2024

    • Author(s)
      武藤太一、山下知輝、甘中健登、鈴木博元、上原知也
    • Organizer
      日本薬学会第144年会
    • Data Source
      KAKENHI-PROJECT-23K27543
  • [Presentation] 211Atによるα線治療を目的としたネオペンチる基を有するFAPI誘導体の研究2023

    • Author(s)
      菅原一真、甘中健登、鈴木博元、上原知也
    • Organizer
      第20回次世代を担う若手のためのフィジカル・ファーマフォーラム
    • Data Source
      KAKENHI-PROJECT-22K07660
  • [Presentation] ネオペンチル標識基を用いたPSMA標的薬剤の211Atへの展開2023

    • Author(s)
      上原知也、山下知輝、安田雄大、平山瑞希、貝塚祐太、甘中健登、鈴木博元、高橋和弘
    • Organizer
      第63回日本核医学会総会
    • Data Source
      KAKENHI-PROJECT-23K27543
  • [Presentation] Development of Radio-halogen-labeled PSMA-targeting ligand with high in vivo stability2023

    • Author(s)
      Tomoki Yamashita, Mizuki Hirayama, Takahiro Yasuda, Uta Kaizuka, Kazuhiro Takahashi, Kento Kannaka, Hiroyuki Suzuki, Tomoya Uehara
    • Organizer
      The 25th International Symposium on Radiopharmaceutical Sciences
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K27543
  • [Presentation] がんのα線治療を目指したアスタチン-211標識FAPI誘導体の研究2023

    • Author(s)
      菅原一真、甘中健登、鈴木博元、上原知也
    • Organizer
      第6回日本核医学会分科会 放射性薬品科学研究会 第22回放射性医薬品・画像診断薬研究会
    • Data Source
      KAKENHI-PROJECT-22K07660
  • [Presentation] ネオペンチル型標識基を用いたPSMA標的α線治療薬剤の研究2023

    • Author(s)
      山下知輝、甘中健登、鈴木博元、貝塚祐太、安田雄大、平山瑞希、高橋和弘、上原知也
    • Organizer
      第6回日本核医学会分科会放射性薬品科学研究会/第22回放射性医薬品・画像診断薬研究会
    • Data Source
      KAKENHI-PROJECT-23K27543
  • [Presentation] 腎放射活性の低減に刷子縁膜酵素を利用した抗体フラグメント標識薬剤のCu-64への応用2019

    • Author(s)
      喜瀬翔太、上原知也、小林まどか、鈴木博元、荒野泰
    • Organizer
      第3回日本核医学会分科会放射性医薬品科学研究会
    • Data Source
      KAKENHI-PROJECT-17H04258
  • [Presentation] 放射性ガリウム標識抗体フラグメントの非特異的腎集積を低減させる標識薬剤の開発2016

    • Author(s)
      上原知也、横山幹、鈴木博元、荒野泰
    • Organizer
      日本薬学会第135年会
    • Place of Presentation
      東京
    • Year and Date
      2016-03-27
    • Data Source
      KAKENHI-PROJECT-25713045
  • [Presentation] 標的への集積向上を目的とした放射性ガリウム化合物の新規設計2015

    • Author(s)
      上原知也
    • Organizer
      第15回放射性医薬品・画像診断薬研究会
    • Place of Presentation
      京都
    • Year and Date
      2015-09-12
    • Data Source
      KAKENHI-PROJECT-25713045
  • [Presentation] SPECT装置を用いたイメージングとそのプローブ開発2014

    • Author(s)
      上原知也
    • Organizer
      第58回日本薬学会関東支部大会
    • Place of Presentation
      東京
    • Year and Date
      2014-10-04
    • Invited
    • Data Source
      KAKENHI-PROJECT-25713045
  • [Presentation] A-Ga-68-labeling reagent liberating Ga--58-NOTA-conjugated methionine from low molecular weight polypeptides in lysosomes for low renal radioactivity levels2013

    • Author(s)
      Tomoya Uehara,Mai Kinoshita, Takemi Rokugawa, Guerra Gomez Fransicsco L, Hirofumi Hanaoka, Yasushi Arano
    • Organizer
      The 20 th International Symposium on Radiopharmaceutical Sciences
    • Place of Presentation
      Jeju (Korea)
    • Data Source
      KAKENHI-PROJECT-25713045
  • [Presentation] 腎放射活性の低減を目的とした放射性ガリウム標識RGDペプチドの開発2013

    • Author(s)
      趙 天会,上原知也,根本創紀,花岡宏史,荒野 泰
    • Organizer
      第13回放射性医薬品・画像診断研究会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-25713045
  • [Presentation] 骨疾患部に選択的に集積する^<99m>Tc標識薬剤の開発2010

    • Author(s)
      上原知也
    • Organizer
      日本核医学会
    • Place of Presentation
      大宮ソニックシティー(大宮)
    • Year and Date
      2010-11-11
    • Data Source
      KAKENHI-PROJECT-21791172
  • [Presentation] 骨疾患部に選択的に集積する^<99m>Tc標識薬剤の開発2010

    • Author(s)
      上原知也
    • Organizer
      日本核医学会
    • Place of Presentation
      大宮
    • Year and Date
      2010-11-11
    • Data Source
      KAKENHI-PROJECT-21791172
  • [Presentation] ^<99m>Tc(CO)_3錯体の生成収率および安定性に及ぼす配位子分子内ピリジン性窒素数の影響2009

    • Author(s)
      平林正次, 上原知也, 鈴木優章, 根矢三郎, 荒野 泰
    • Organizer
      日本薬学会第129年会
    • Place of Presentation
      京都
    • Year and Date
      2009-03-26
    • Data Source
      KAKENHI-PROJECT-18390328
  • [Presentation] 肝動脈塞栓療法併用アイソトープ治療を目的とする放射性ヨウ素標識環状ポリアミン誘導体の合成と基礎的検討2009

    • Author(s)
      小川愛那, 富岡直子, 黒川将弘, 初芝清徳, 松島理, 秋澤宏行, 上原知也, 荒野泰
    • Organizer
      日本薬学会第129年会
    • Place of Presentation
      京都
    • Year and Date
      2009-03-26
    • Data Source
      KAKENHI-PROJECT-18390328
  • [Presentation] 99mTc(CO)3錯体の生成収率に及び安定性に及ぼす配位子分子内ピリジン性窒素数の影響2009

    • Author(s)
      平林正次、上原知也、鈴木優章、根矢三郎、荒野泰
    • Organizer
      日本薬学会第129年会
    • Place of Presentation
      京都国際会館
    • Year and Date
      2009-03-26
    • Data Source
      KAKENHI-PROJECT-18390328
  • [Presentation] 抗体のオクタアルギニン修飾が細胞への結合性に及ぼす影響2009

    • Author(s)
      宮本怜、秋澤宏行、上原知也、東佑翼、二木史郎、花岡宏史、飯田靖彦、遠藤啓吾、荒野泰
    • Organizer
      日本薬学会第129年会
    • Place of Presentation
      京都国際会館
    • Year and Date
      2009-03-26
    • Data Source
      KAKENHI-PROJECT-20659186
  • [Presentation] 抗体のオクタアルギニン修飾が細胞への結合性に及ぼす影響2009

    • Author(s)
      宮本怜, 秋澤宏行, 上原知也, 東祐翼, 二木史郎, 花岡宏史, 飯田靖彦, 遠藤啓吾, 荒野泰
    • Organizer
      日本薬学会第129年会
    • Place of Presentation
      京都
    • Year and Date
      2009-03-27
    • Data Source
      KAKENHI-PROJECT-18390328
  • [Presentation]2008

    • Author(s)
      秋澤宏行, 宮本怜, 上原知也, 東祐翼, 中瀬生彦, 二木史郎, 花岡宏史, 飯田靖彦, 遠藤啓吾, 荒野泰
    • Organizer
      第48回日本核医学会
    • Place of Presentation
      千葉
    • Year and Date
      2008-10-25
    • Data Source
      KAKENHI-PROJECT-18390328
  • [Presentation] In-111標識抗テネイシンC抗体による急性心筋梗塞後組織修復の非侵襲的評価法の開発2008

    • Author(s)
      小高謙一, 上原知也, 荒野泰, 長谷川洋, 田所裕之, 吉田勝哉, 今中恭子, 廣江道昭, 棚田修二, 小室一成, 入江俊章
    • Organizer
      第48回日本核医学会
    • Place of Presentation
      千葉
    • Year and Date
      2008-10-25
    • Data Source
      KAKENHI-PROJECT-18390328
  • [Presentation] Prolonged retention of antibody on target by modification with arginine-rich peptide2008

    • Author(s)
      Miyamoto R, Akizawa H, Uehara T, Takayama K, Futaki S, Hanaoka H, Iida Y, Endo K, Arano Y.
    • Organizer
      Society of Nuclear Medicine 2008 Annual Meeting
    • Place of Presentation
      New Orleans
    • Year and Date
      2008-06-16
    • Data Source
      KAKENHI-PROJECT-18390328
  • [Presentation] デンドリマーの体内動態制御に関する基礎的研究2008

    • Author(s)
      鈴木博元、石井大輔、上原知也、秋澤宏行、高間雅志、村上正裕、荒野泰
    • Organizer
      第48回日本核医学会総会
    • Place of Presentation
      千葉幕張メッセ
    • Year and Date
      2008-10-25
    • Data Source
      KAKENHI-PROJECT-20659186
  • [Presentation] 安定なテクネチウムトリカルボニル錯体を形成する新規標識薬剤の開発2008

    • Author(s)
      平林正次、上原知也、荒野泰
    • Organizer
      第47回日本核医学会総会
    • Place of Presentation
      千葉幕張メッセ
    • Year and Date
      2008-10-25
    • Data Source
      KAKENHI-PROJECT-18390328
  • [Presentation] 肝動脈塞栓療法併用アイソトープ治療を目的とする環状ポリアミン誘導体の比較2008

    • Author(s)
      秋澤 宏行, 富岡直子, 黒川将弘, 上原知也, 荒野泰
    • Organizer
      第48回日本核医学会
    • Place of Presentation
      千葉
    • Year and Date
      2008-10-24
    • Data Source
      KAKENHI-PROJECT-18390328
  • [Presentation] 標的組織での集積向上を目的とするラジオアイソトープ標識抗体のアルギニンリッチペプチド修飾2008

    • Author(s)
      宮本怜、秋澤宏行、上原知也、花岡宏史、飯田靖彦、遠藤啓吾、荒野泰
    • Organizer
      第47回日本核医学会総会
    • Place of Presentation
      千葉幕張メッセ
    • Year and Date
      2008-10-25
    • Data Source
      KAKENHI-PROJECT-18390328
  • [Presentation] デンドリマーの体内動態制御に関する基礎的研究2008

    • Author(s)
      上原知也, 鈴木博元, 石井大輔, 秋澤宏行, 高間雅志, 村上正裕, 荒野泰
    • Organizer
      第48回日本核医学会
    • Place of Presentation
      千葉
    • Year and Date
      2008-10-24
    • Data Source
      KAKENHI-PROJECT-18390328
  • [Presentation] アミノ酸輸送システムAを標的とした[N-methyl-^<11>C]MeAIB合成の基礎的検討2008

    • Author(s)
      加川信也, 西井龍一, 東達也, 上原知也, 岸辺喜彦, 岩崎甚衛, 川井恵一, 荒野泰
    • Organizer
      第48回日本核医学会
    • Place of Presentation
      千葉
    • Year and Date
      2008-10-24
    • Data Source
      KAKENHI-PROJECT-18390328
  • [Presentation] 安定なテクネチウムトリカルボニル錯体を形成する新規標識薬剤の開発2008

    • Author(s)
      平林正次, 上原知也, 荒野泰
    • Organizer
      第48回日本核医学会
    • Place of Presentation
      千葉
    • Year and Date
      2008-10-24
    • Data Source
      KAKENHI-PROJECT-18390328
  • [Presentation] 多価効果による標的分子への集積向上を目指した新たな^<99m>Tc標識薬剤の設計2008

    • Author(s)
      上原知也, 平良優一郎, 土屋将夫, 秋澤宏行, 荒野泰
    • Organizer
      第48回日本核医学会
    • Place of Presentation
      千葉
    • Year and Date
      2008-10-24
    • Data Source
      KAKENHI-PROJECT-18390328
  • [Presentation] A simple and convenient method to estimate therapeutic radiopharmaceuticals for transchatheter arterial embolization2008

    • Author(s)
      Tomioka N, Akizawa H, Uehara T, Sun W-J, Kurokawa M, Matsushima S, Hatsushiba K, Hashimoto K, Arano Y.
    • Organizer
      Society of Nuclear Medicine 2008 Annual Meeting
    • Place of Presentation
      New Orleans
    • Year and Date
      2008-06-16
    • Data Source
      KAKENHI-PROJECT-18390328
  • [Presentation] アミノ酸輸送システムAの基質による癌の治療効果判定2008

    • Author(s)
      上原知也
    • Organizer
      第3回トランスホーター研究会年会
    • Place of Presentation
      京都大学薬学部
    • Data Source
      KAKENHI-PROJECT-19790856
  • [Presentation] 多価効果による標的分子への集積向上を目指した新たな99mTc標識薬剤の設計2008

    • Author(s)
      宮本怜、秋澤宏行、上原知也、東佑翼、二木史郎、花岡宏史、飯田靖彦、遠藤啓吾、荒野泰
    • Organizer
      第48回日本核医学会総会
    • Place of Presentation
      千葉幕張メッセ
    • Year and Date
      2008-10-25
    • Data Source
      KAKENHI-PROJECT-20659186
  • [Presentation] 多価効果による標的分子への集積向上を目指した新たな99mTc標識薬剤の設計2008

    • Author(s)
      平良優一郎、土屋将夫、内田雪絵、上原知也、秋澤宏行、荒野泰
    • Organizer
      第47回日本核医学会総会
    • Place of Presentation
      千葉幕張メッセ
    • Year and Date
      2008-10-25
    • Data Source
      KAKENHI-PROJECT-18390328
  • [Presentation] アミノ酸輸送システムAの基質による癌の治療効果判定2008

    • Author(s)
      上原知也
    • Organizer
      3回トランスポーター研究会年会
    • Place of Presentation
      京都大学薬学部
    • Data Source
      KAKENHI-PROJECT-19790856
  • [Presentation] アミノ酸輸送システムAの基質による癌の治療効果判定2007

    • Author(s)
      上原知也
    • Organizer
      第47回日本核医学会学術総会
    • Place of Presentation
      仙台
    • Year and Date
      2007-11-05
    • Data Source
      KAKENHI-PROJECT-19790856
  • [Presentation] 非特異的腎集積を低減する金属RI標識抗体フラグメントの開発2007

    • Author(s)
      上原 知也, 平林 正次, 秋澤 宏行, 荒野 泰
    • Organizer
      第47回日本核医学会総会
    • Place of Presentation
      仙台国際センター
    • Year and Date
      2007-11-04
    • Data Source
      KAKENHI-PROJECT-18390328
  • [Presentation] 標的分子への集積向上を目的とする新たな^<99m>Tc標識薬剤の設計2007

    • Author(s)
      上原知也, 土屋将夫, 内田雪絵, 平良優一郎, 秋澤宏行, 荒野泰
    • Organizer
      第47回日本核医学会
    • Place of Presentation
      仙台
    • Year and Date
      2007-11-05
    • Data Source
      KAKENHI-PROJECT-18390328
  • [Presentation] 標的分子への集積向上を目的とする新たな^<99m>Tc標識薬剤の設計2007

    • Author(s)
      上原 知也, 土屋 将夫, 内田 雪絵, 秋澤 宏行, 荒野 泰
    • Organizer
      第47回 日本核医学会総会
    • Place of Presentation
      仙台国際センター
    • Year and Date
      2007-11-04
    • Data Source
      KAKENHI-PROJECT-18659342
  • [Presentation] 非特異的腎集積を低減する金属RI標識抗体フラグメントの開発2007

    • Author(s)
      上原知也, 平林正次, 秋澤宏行, 荒野泰
    • Organizer
      第47回日本核医学会
    • Place of Presentation
      仙台
    • Year and Date
      2007-11-04
    • Data Source
      KAKENHI-PROJECT-18390328
  • [Presentation] デンドリマーの化学修飾による動態制御2007

    • Author(s)
      土屋将夫, 石井大輔, 上村友恵, 内田雪絵, 上原知也, 秋澤宏行, 荒野泰
    • Organizer
      日本薬学会第128年会
    • Place of Presentation
      富山
    • Year and Date
      2007-03-28
    • Data Source
      KAKENHI-PROJECT-18390328
  • [Presentation] 腎放射活性の低減を目的とする低分子ポリペプチドGa標識薬剤に関する基礎的研究

    • Author(s)
      上原知也,横山幹,趙天会,花岡宏史,荒野泰
    • Organizer
      第54回日本核医学会総会
    • Place of Presentation
      大阪
    • Year and Date
      2014-11-06 – 2014-11-08
    • Data Source
      KAKENHI-PROJECT-25713045
  • [Presentation] A novel chemical design of Ga-67/68 labeled probes based on chelation-madiated multivalency to enhance target accumulation

    • Author(s)
      Tomoya Uehara, Yasushi Arano
    • Organizer
      International seminar on pharmaceutical science and technology2014
    • Place of Presentation
      Bandung, Indonesia
    • Year and Date
      2014-09-16 – 2014-09-19
    • Invited
    • Data Source
      KAKENHI-PROJECT-25713045
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