GEJYO Fumitake 下條文武

… Alternative Names

下条文武ゲジヨウフミタケ

下條文武ゲジヨウフミタケ

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Researcher Number	20126410
External Links
Affiliation (based on the past Project Information) *help	2007 – 2008: Niigata University, 学長 2006: 新潟大学, 医歯学総合病院・教授, 教授 2003 – 2006: NIIGATA UNIVERSITY, Medical and dental hospital, Professor, 医歯学総合病院, 教授 2001 – 2003: Graduate School of Medical and Dental Sciences, NIIGATA UNIVERSITY, Professor, 大学院・医歯学総合研究科, 教授 1999 – 2000: Niigata University, Medicine(II), Professor., 医学部, 教授 … More 1995 – 1998: 福井医科大学, 医学部, 教授 1990 – 1992: 新潟大学, 医学部, 助教授 1987 – 1988: 新潟大学, 医学部, 助教授 1986: 新大, 医学部, 助教授 Less
Review Section/Research Field	Principal Investigator 内科学一般 / Kidney internal medicine / Biological Sciences / Kidney internal medicine Except Principal Investigator Kidney internal medicine / Experimental pathology
Keywords	Principal Investigator 透析アミロイドーシス / β_2-ミクログロブリン / 血液透析 / アミロイドーシス / 遺伝子多型 / IgA腎症 / 動脈硬化 / 慢性腎不全 / 腎不全 / アミロイド線維 … More / 手根管症候群 / 慢性腎臓病 / SNP / 心血管疾患 / メガリン / β_2ーミクログロブリン / アミロイド円柱 / β_2ーmicroglobulin / アミロイド / high flux膜ダイアライザー / 骨透亮像 / β_2-microglobulin / アミロイドP成分 / コラーゲン / Life Survival / Long-term Hemodialysis / Arteriosclerosis / Genetic Polymorphism / HD associated Amyloidosis / Secondary Hyperparathyroidism / Hemodialysis / Chronic Renal Failure / 透析皮膚掻痒症 / 生命予後 / 長期透析 / 二次性副甲状腺機能亢進症 / 透析療法 / genetic polymorphism / IgA nephropathy / Schoenlein-Henoch purpura / anti-glomerular basement membrane antibody / effector T cell / microscopic polyarteritis / autoimmune systemic vasculitis / 転写因子 / 細胞内情報伝達系 / オステオポンチン / 半月体形成性腎炎 / STAT-1 / 細胞内情報伝達 / T細胞 / サイトカイン / 尿T細胞 / Schoenlein-Henoch紫斑病 / 抗糸球体基底膜抗体 / エフェクター型T細胞 / 顕微鏡的多発動脈炎 / 自己免疫性血管炎 / fAβィイD22ィエD2-m / advanced glycation end products / first-order kinetics / amyloid fibril / β2-microgulobulin / dialysis amyloidosis / 一次反応速度論モデル / fAβ2-m線維伸長反応 / チオフラビンT / β2-microglobulin / β_2ミクログロブリン / fAB_2-m / AGEs(advanced glycation end products) / 一次反応速度論 / B_2ミクログロブリン / 透析アミロイド / microinjection / hemodialysis / transgenic mouse / dialysis-related amyloidosis / beta2-microglobulin / マイクロインジェクション / トランスジェニックマウス / 骨レ線透亮像 / 【β_2】-microglobulin / 長期血液透析 / アムニオンレス / キュビリン / NMHC IIA / 近位尿細管上皮細胞 / アンジオテンシンII / インスリン / カルシウム代謝異常 / 慢性炎症 / 栄養障害 / 脂質代謝異常 / RAS / レニン-アンジオテンシン系 / 高血圧 / 慢性糸球体腎炎 / 前向き調査 / 維持血液透析 / 細胞移植 / アミロイド線維伸長反応 / プロテオグリカン / グリコサミノグリカン / MIF / L-FABP / レプチン / トリフルオロエタノール / ドデシル硫酸ナトリウム / 遺伝子発現 / 水晶発振子マイクロバランス法 / LFABP / AGE / 透析アミロードシス / 腎疾患 / ネフローゼ症候群 / ループス腎炎 / 腎生検 / 糸球体腎炎 / クラスタリング / 発現遺伝子プロファイル / DNAマイクロアレイ / アイソトープ標識 / ^<131>Iーβ_2ーミクログロブリン / アミロイド結石 / アミロイド-シス / 骨アミロイド / クロラミンT法 / ^<125>Iーβ_2ーミクログロブリン / カルシウム / 電子線マイクロアナライザ- … More Except Principal Investigator IgA nephropathy / AGE / tonsil / outer membrane / Haemophilus parainfluenzae / α addducin / macrophage metalloelastase / diabetic nephropathy / dialysis-related amyloidosis / uremic toxin protein / megalin / エンドサイトーシス / 透析アミロイドーシス / 再生医学 / 糖尿病性腎症 / 尿毒素蛋白 / メガリン / lymphocyte / lymphocyte function / mucosal immunity / Dent's disease / leptin / regenerative medicine / 肝型脂肪酸結合蛋白 / Dent病 / レプチン / aldosterone Synthase / DNA microarray / single nucleotide polymorphism / crescentic glomerulonephritis / refractory glomerulonephritis / ネフローゼ症候群 / 腎生検 / クラスタリング / DNAマイクロアレイ解析 / ウテログロビン / 多価免疫受容体 / FcR受容体 / CYP11B2 / アンジオテンシノーゲン / α-adducin / Macrophage mettalloelastase / 高血圧 / Aldosterone Synthase / DNAマイクロアレイ / 遺伝子多型 / 半月体形成性糸球体腎炎 / IgA腎症 / 難治性糸球体腎炎 / cytokine / tissue engineering / β_2-microglobulin / proximal tubule / Heymann腎炎 / ELISA / 尿 / 血液浄化療法 / PI3キナーゼ / ゲンタマイシン腎症 / β_2-ミクログロブリン / 尿中マーカー / advanced glycation endproduct / β_2ミクログロブリン / 透析アミロードーシス / β2-ミクログロブリン / 近位尿細管 / conformational change / nuclei / antioxidants / apolipoprotein E / amyloid β-peptide 1-42 / nucleation dependent polymerization model / β-amyloid fibril / Alzheimer's disease / ロジスティック方程式 / βペプチド1-42 / 立体構造変化 / 抗酸化剤 / 重合核 / アポリポ蛋白E / Aβ蛋白1-42 / 重合核依存性重合モデル / βアミロイド線維 / アルツハイマー病 / onsil / out membrane Less

透析アミロイドーシスを予防するための細胞移植療法の開発:メガリン発現細胞の樹立Principal Investigator
- Principal Investigator
  
  下條文武 (下条文武)
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Kidney internal medicine
- Research Institution
  Niigata University
腎不全リスク推定システムに基づくオーダーメイド医療の確立Principal Investigator
- Principal Investigator
  
  下条文武
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Niigata University
腎機能障害と動脈硬化促進の共通因子探索のためのネットワークの構築Principal Investigator
- Principal Investigator
  
  下条文武
- Project Period (FY)
  2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Niigata University
腎不全責任遺伝子群の相互作用解析システムの構築Principal Investigator
- Principal Investigator
  
  下条文武
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Niigata University
腎不全における動脈硬化促進因子探索のためのネットワークの構築Principal Investigator
- Principal Investigator
  
  下条文武
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Niigata University
β_2-mアミロイド線維形成の阻害物質の探索Principal Investigator
- Principal Investigator
  
  下条文武
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Kidney internal medicine
- Research Institution
  Niigata University
Molecular genetic analysis of various types of complications in patients with long-term dialysis therapyPrincipal Investigator
- Principal Investigator
  
  GEJYO fumitake
- Project Period (FY)
  2003 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Niigata University
Analysis of the functions of the endocytosis receptor megalin and its application to nephrology and regenerative medicine
- Principal Investigator
  
  SAITO Akihiko
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  NIIGATA UNIVERSITY
ヒト腎疾患に対する遺伝子レベルの診断法の確立と治療法の開発Principal Investigator
- Principal Investigator
  
  下条文武
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Niigata University
Analysis of onset mechanism in refractory glomerulonephritis with DNA microanray
- Principal Investigator
  
  UENO Mitsuhiro
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Niigata University
The study of the mechanisms of autoimmune systemic vasculitis.Principal Investigator
- Principal Investigator
  
  GEJYO Fumitake
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  NIIGATA UNIVERSITY
Studies on the inhibitory mechanism of biological molecules and antioxidants for Alzheimer's β-amyloid fibril formation.
- Principal Investigator
  
  NAIKI Hironobu
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  FUKUI MEDICAL UNIVERSITY
Analysis of physiological and pathophysiological functions of megalin in the proximal tubules and clinical application of its molecular features
- Principal Investigator
  
  SAITO Akihiko
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Niigata University
Study of pathogenesis of IgA nephropathy
- Principal Investigator
  
  SUZUKI Satoru
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Fukui Medical University
Studies on dialysis-related amyloid fibril formation by a in vitro kinetic modelPrincipal Investigator
- Principal Investigator
  
  GEJYO Fumitake
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Niigata University
  福井医科大学
Study of pathogenesis of IgA nephropathy
- Principal Investigator
  
  SUZUKI Satoru
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Fukui Medical University
DEVELOPMENT OF MODEL MOUSE FOR DIALYSIS-RELATED AMYLOIDOSIS AND ITS APPLICATION FOR THE ANALYSIS OF PATHOGENESIS.Principal Investigator
- Principal Investigator
  
  GEJYO Fumitake
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  FUKUI MEDICAL SCHOOL
透析アミロイドーシス発症におけるN末端β_2-ミクログロブリンの関与Principal Investigator
- Principal Investigator
  
  下条文武
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  Niigata University
透析アミロイド症におけるβ_2ーミクログロブリンとそのフラグメントの役割についてPrincipal Investigator
- Principal Investigator
  
  下条文武
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  Niigata University
β_2ーミクログロブリンのアミロイド線維形成と組織沈着機序に関する研究Principal Investigator
- Principal Investigator
  
  下条文武
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  Niigata University
透析アミロイドーシスの成因と治療に関する研究Principal Investigator
- Principal Investigator
  
  下条文武
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  内科学一般
- Research Institution
  Niigata University
長期血液透析に合併するアミロイドーシスの発症機序に関する研究Principal Investigator
- Principal Investigator
  
  下條文武
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  Niigata University

All 2008 2007 2006 2005 2004

All Journal Article Book

[Book] 最新透析医学2008
- Author(s)
  飯野則昭, 斎藤亮彦, 下条文武
- Publisher
  腎代替医療への先端技術の応用
- Data Source
  KAKENHI-PROJECT-19659218
[Journal Article] New advances in renal amyloidosis.2008
- Author(s)
  Nishi N, Alchi B, Imai N, Gejyo F
- Journal Title
  
  Clinical Experimental Nephrology 12
  
  Pages: 93-101
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659218
[Journal Article] Hemodialysis related amyloidosis (DRA)-recent basic understanding and clinical strategy.2007
- Author(s)
  Nishi S, Imai N, Gejyo F
- Journal Title
  
  4th China-Japan Kidney Conferene Program
  
  Pages: 17-18
- Data Source
  KAKENHI-PROJECT-19659218
[Journal Article] Role of megalin, a proximal tubular endocytic receptor, in calcium and phosphate homeostasis.2007
- Author(s)
  Saito A, Lino N, Takeda T, Gejyo F
- Journal Title
  
  Therapeutic Apheresis and Dialysis 11
- Data Source
  KAKENHI-PROJECT-19659218
[Journal Article] Aβ-2M-amyloidosis and related bone diseases.2006
- Author(s)
  Kazama JJ, Yamamoto S, Takahashi N, Ito Y, Maruyama H, Narita I, Gejyo F
- Journal Title
  
  J Bone Miner Metab 24(2)
  
  Pages: 182-184
- Data Source
  KAKENHI-PROJECT-15659202
[Journal Article] 腎不全患者に集中発生したスギヒラタケ脳症2006
- Author(s)
  下条文武, ほか
- Journal Title
  
  日本内科学会雑誌 95・7
  
  Pages: 1310-1315
- Data Source
  KAKENHI-PROJECT-15390267
[Journal Article] Significance of proximal tubular metabolism of advanced glycation end products in kidney diseases.2005
- Author(s)
  Saito A, Takeda T, Sato K, Hama H, Tanuma A, Kaseda R, Suzuki Y, Gejyo F
- Journal Title
  
  Ann NY Acad Sci. 1043
  
  Pages: 637-643
- Data Source
  KAKENHI-PROJECT-15659202
[Journal Article] A novel type of encephalopathy associated with mushroom Sugihiratake ingestion in patients with chronic kidney diseases2005
- Author(s)
  Gejyo F, et al.
- Journal Title
  
  Kidney International 68・1
  
  Pages: 188-192
- Data Source
  KAKENHI-PROJECT-15390267
[Journal Article] Molecular interactions in the formation and deposition of β2-microglobulin-related amyloid fibrils.2005
- Author(s)
  Naiki H, Yamamoto S, Hasegawa K, Yamaguchi I, Goto Y, Gejyo F
- Journal Title
  
  Amyloid 12(1)
  
  Pages: 15-25
- Data Source
  KAKENHI-PROJECT-15659202
[Journal Article] Evidence for megalin-mediated proximal tubular uptake of L-FABP, a carrier of potentially nephrotoxic molecules.2005
- Author(s)
  Oyama Y, Takeda T, Hama H, Tanuma A, Hino N, Sato K, Kaseda R, Ma M, Yamamoto T, Fujii H, Kazama JJ, Odani S, Terada Y, Mizuta K, Gejyo F, Saito A
- Journal Title
  
  Lab Invest. 85(4)
  
  Pages: 522-531
- Data Source
  KAKENHI-PROJECT-15659202
[Journal Article] Historical background and clinical treatment of dialysis-related amyloidosis.2005
- Author(s)
  Yamamoto S, Gejyo F
- Journal Title
  
  Biochim Biophys Acta. 1753(1)
  
  Pages: 4-10
- Data Source
  KAKENHI-PROJECT-15659202
[Journal Article] Kinetic analysis of the polymerization and depolymerization of β(2)-microglobulin-related amyloid fibrils in vitro.2005
- Author(s)
  Yamamoto S, Hasegawa K, Yamaguchi I, Goto Y, Gejyo F, Naiki H
- Journal Title
  
  Biochim Biophys Acta. 1753(1)
  
  Pages: 34-43
- Data Source
  KAKENHI-PROJECT-15659202
[Journal Article] 2004 Japanese Society for Dialysis Therapy guidelines for renal anemia in chronic hemodialysis patients2004
- Author(s)
  Gejyo F, et al.
- Journal Title
  
  Therapeutic Apheresis and Dialysis 8・6
  
  Pages: 443-459
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390267
[Journal Article] 2004 Japanese Society for Dialysis Therapy guidelines for renal anemia in chronic hemodialysis patients2004
- Author(s)
  F.Gejyo
- Journal Title
  
  Therapeutic Apheresis and Dialysis 8・6
  
  Pages: 443-459
- Data Source
  KAKENHI-PROJECT-15390267
[Journal Article] 2004 Japanese Society for Dialysis Therapy guidelines for renal anemia in chronic hemodialysis patients.2004
- Author(s)
  Gejyo F, et al.
- Journal Title
  
  Therapeutic Apheresis and Dialysis 8・6
  
  Pages: 443-459
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390267
[Journal Article] 2004 Japanese Society for Dialysis Therapy guidelines for renal anemia in chronic hemodialysis patients2004
- Author(s)
  F.Gejyo
- Journal Title
  
  Therapeutic Apheresis and Dialysis 8・6
  
  Pages: 443-459
- Data Source
  KAKENHI-PROJECT-16639010

1. NARITA Ichiei (20272817)

# of Collaborated Projects: 7 results

# of Collaborated Products: 0 results
2. SAKATSUME Minoru (70334662)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
3. SAITO Akihiko (80293207)

# of Collaborated Projects: 4 results

# of Collaborated Products: 4 results
4. SUZUKI Satoru (00206484)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. KAZAMA Junichiro (10345499)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. NAIKI Hironobu (10227704)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 木村秀樹 (20283187)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. 長谷川伸

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. 本間則行

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. KUWANO Ryozo (20111734)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. SHIRTTIZU Fujio (40012728)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. UENO Mitsuhiro (90260546)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. TAKEDA Tetsuro (10361924)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. TABATA Yasuhiko (50211371)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 原田孝司 (90128207)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 平方秀樹 (70181146)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 菊池健次郎 (30045455)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 今井圓裕 (00223305)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 鶴屋和彦 (20372740)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 横山仁 (50191531)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 荒川正昭 (80069012)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. YAMAZAKI Hajime

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 黒田毅

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

GEJYO Fumitake 下條 文武

下条 文武 ゲジヨウ フミタケ

下條 文武 ゲジヨウ フミタケ

Research Projects

Research Products

Co-Researchers

透析アミロイドーシスを予防するための細胞移植療法の開発:メガリン発現細胞の樹立Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

腎不全リスク推定システムに基づくオーダーメイド医療の確立Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

腎機能障害と動脈硬化促進の共通因子探索のためのネットワークの構築Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

腎不全責任遺伝子群の相互作用解析システムの構築Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

腎不全における動脈硬化促進因子探索のためのネットワークの構築Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

β_2-mアミロイド線維形成の阻害物質の探索Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular genetic analysis of various types of complications in patients with long-term dialysis therapyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of the functions of the endocytosis receptor megalin and its application to nephrology and regenerative medicine

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ヒト腎疾患に対する遺伝子レベルの診断法の確立と治療法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of onset mechanism in refractory glomerulonephritis with DNA microanray

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The study of the mechanisms of autoimmune systemic vasculitis.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies on the inhibitory mechanism of biological molecules and antioxidants for Alzheimer's β-amyloid fibril formation.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of physiological and pathophysiological functions of megalin in the proximal tubules and clinical application of its molecular features

Principal Investigator

GEJYO Fumitake 下條文武

下条文武ゲジヨウフミタケ

下條文武ゲジヨウフミタケ