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MIYASAKA Nobuyuki  宮坂 信之

ORCIDConnect your ORCID iD *help
… Alternative Names

宮坂 信之  ミヤサカ ノブユキ

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Researcher Number 30157622
Other IDs
External Links
Affiliation (Current) 2025: 東京科学大学, その他の部局等, 非常勤講師
Affiliation (based on the past Project Information) *help 2014: 東京医科歯科大学, 医学部附属病院, 非常勤講師
2013: 東京医科歯科大学, 名誉教授
2013: 東京医科歯科大学, 医学部, 名誉教授
2013: 東京医科歯科大学, 医学部, 非常勤講師
2011 – 2012: 東京医科歯科大学, 医歯(薬)学総合研究科, 教授 … More
2010 – 2011: 東京医科歯科大学, 大学院・医歯学総合研究科, 教授
2009: 東京医科歯科大学, 医歯学総合研究科, 教授
2008: 東京医科歯科大学大学院, 医歯学総合研究科, 教授
2007 – 2008: 東京医科歯科大学, 大学院・医歯学総合研究科, 教授
2005 – 2006: Tokyo Medical and Dental University, Graduate School Department of Medicine and Rheumatology, Professor, 大学院医歯学総合研究科, 教授
2000 – 2005: 東京医科歯科大学, 大学院・医歯学総合研究科, 教授
2004: Tokyo Medical and Dental University, Graduate school, Professor, 大学院・ 医歯学総合研究科, 教授
2002: 東京医科歯科大学, 医歯学総合研究科, 教授
2001: 東京医科歯科大学, 大学院・生体応答学系, 教授
1995 – 1999: 東京医科歯科大学, 医学部, 教授
1992 – 1994: 東京医科歯科大学, 難治疾患研究所, 教授
1988 – 1989: 東京女子医科大学, 医学部, 助教授
1986: 東京女医大, その他, 助教授
1986: 東京女子医科大学, 医学部, 助教授 Less
Review Section/Research Field
Principal Investigator
内科学一般 / 膠原病・アレルギー・感染症内科学 / Biological Sciences
Except Principal Investigator
膠原病・アレルギー・感染症内科学 / 内科学一般 / Applied pharmacology / Respiratory organ internal medicine / 病態科学系歯学(含放射線系歯学) / 寄生虫学(含医用動物学) / Hematology / Medical pharmacy / Surgical dentistry
Keywords
Principal Investigator
慢性関節リウマチ / サイトカイン / 関節リウマチ / 遺伝子療法 / サイクリン依存性キナーゼインヒビター / 遺伝子治療 / 細胞周期 / 滑膜増殖 / MAdCAM-1 / サイクリン依存性キナーゼ … More / gene therapy / adhesion molecule / 接着分子 / シェーグレン症候群 / サイクリン依存性キナーゼ阻害因子 / STAT4 / インターロイキン-12 / STAT / animal model / adenovirus vector / cyclin-dependent kinase inhibitors / rheumatoid arthritis (RA) / 低分子化合物 / 増殖抑制 / 治療 / 内科 / 膠原病 / 動物モデル / アデノウイルスベクター / 関節リウマチ(RA) / gut-associated lymphoid tissues(GALT) / monoclonal antibody / adjuvant arthritis / oral tolerance / GALT / ホーミング / 粘膜免疫 / 関節炎 / MAdCAM-1分子 / 腸管附属リンパ組織 / モノクローナル抗体 / アジュバント関節炎 / 経口寛容 / CDKI / rheumatoid arthritis / サイクリン / autoimmune disease / cytokine / 自己免疫疾患 / vascular endothelial cells / matastasis / ELAM-1 / VCAM-1 / ICAM-1 / 血管内皮細胞 / 癌転移 / インターロイキン6 / B細胞刺激因子 / Esptein-Barr virus / B細胞活性化機構 / 発癌 / ポリクローナル活性化 / B細胞 / MMP-3 / Il-6 / microRNA阻害剤ライブラリー / micro RNA / microRNA / 感染症 / TREM-1 / ケモカインレセプター / ケモカイン / シグナル伝達 / Th1細胞 / 阻害薬 / 受容体 / JAKキナーゼ / インターロイキン12 / サイクリンキナーゼインヒビター / 転写因子 / PDGF / 滑膜細胞 / NFκB / PI3キナーゼ / MAPキナーゼ / JAK / TNFα / Fas抗原 / スフィンゴミエリン / セラミド / アポトーシス / 細胞内シグナル伝達機構 / ハイブリド-マ / インタ-ロイキン … More
Except Principal Investigator
関節リウマチ / cell cycle / rheumatoid arthritis / 細胞周期 / アデノウイルス / bone morphogenic protein / 遺伝子治療 / p16 / サイクリン依存性キナーゼ / 慢性関節リウマチ / IL-5 / IgE / IL-4 / Plasmodium berghei / Brugia pahangi / Th2 / Th1 / apoptosis / 生物学的製剤 / 治療 / 膠原病学 / 膠原病 / TNF阻害薬 / 多発性筋炎 / トレランス誘導 / 樹状細胞 / 関節炎 / データベース / 遺伝子療法 / 免疫寛容 / 自己免疫 / IL-2RmRNA / 慢性過敏性肺炎 / EBウイルス / シェーグレン症候群 / treatment / コラーゲン誘導性関節炎 / サイクリン依存性性キナーゼ / chondrocyte / proteoglycan / regenerative medicine / articular chondrocyte / ARC軟骨 / BMP / 軟骨保護遺伝子 / 遺伝子導入 / 3次元培養 / 軟骨 / 軟骨細胞 / プロテオグリカン / 再生医療 / 関節軟骨 / cyclin-dependent kinase inhibitor / ノックアウトマウス / 増殖抑制 / autoimmunity / CD8T cells / polymiositis / CD8T細胞 / gene therapy / 合成ぺプチド / Western blot / リンパ球増殖 / 急性鳥飼病 / 慢性鳥飼病 / TGF-β / TNF-α / IL-6 / 合成ペプチド / 特異的病因抗原 / 細胞性免疫 / 特発性肺線維症 / Adenovirus / Gene Therapy / CDKI / Rheumatoid Arthritis / アデノウィルス / p21 / Plasmodium bergi / Brugia pahani / I-L5 / latent membrane protein-1 / Epstein-Barr virus / Bcl-2 / Lymphoproliferative disorders / Sjogren's syndrome / アポトーシス / リンパ増殖性病変 / シェ-グレン症候群 / 血管内凝固 / 血管内皮細胞 / 血液凝固の制御 / スロンビン / プロテインC / モノクロナル抗体 / スロンボモデュリン / 自然免疫 / シトルリン化 / NETS形成 / 抗好中球細胞質抗体関連血管炎 / カンナビノイド / 薬剤疫学研究 / 日和見肺感染症 / 重篤肺感染症 / 分子標的薬 / 日和見感染症 / 肺感染症 / 免疫抑制療法 / リウマチ性疾患 / マクロファージ / サイクリン依存性キナーゼ阻害因子 / 細胞周期制御 / CDK4/6 / 治療法 / TREM-1 / CDK4/6阻害薬 / TREM-1リガンド / 病理学 / 免疫学 / 薬学 / 臨床 / 内科 / リウマチ学 / CX3CR1 / 血管炎症候群 / 血管炎 / ケモカイン / フラクタルカイン / 悪性腫瘍 / 薬剤適正使用 / 重篤有害事象 / 患者登録システム / 安全性 / 薬剤疫学 / indoleamine 2,3-dioxygenase / indoleamine 2, 3-dioxygenase / 細胞増殖 / 炎症 / microRNA / レフルノミド / 肺合併症 / インフリキシマブ / 間質性肺炎 / タクロリムス / エタネルセプト / 薬剤性肺障害 / 薬剤性肺炎 / ニューモシスチス肺炎 / 抗リウマチ薬 / 医薬品副作用 / 細胞増殖抑制 / 自己抗体 / プロテインチップ / ケースコントロール研究 / ミューモシスチス肺炎 / マウス / 動物モデル / 調節性T細胞 / 細胞治療 / interleukin-10 / ICOS ligand / 発熱 / アンケート / 成人発症スティル病 / 国際シェーグレン症候群シンポジウム / 日本シェーグレン症候群研究会 / 個人調査表 / 現状調査表 / 改訂診断基準 / 査定調査 / 診断基準 / リコンビナント蛋白 / 主要組織適合性抗原 / T細胞抗原受容体 / サイトカイン / GM-CSF / 自己抗原 / 遺伝子免疫 / IL-6mRNA / 鳥飼病 / 特発性間質性肺炎 / BCRF-1 / IL-10 / トランスジェニックマウス Less
  • Research Projects

    (49 results)
  • Research Products

    (134 results)
  • Co-Researchers

    (47 People)
  •  microRNA as a target to develop a novel treatment for rheumatoid arthritis and to clarify a new pathology in rheumatoid arthritisPrincipal Investigator

    • Principal Investigator
      MIYASAKA Nobuyuki
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      膠原病・アレルギー・感染症内科学
    • Research Institution
      Tokyo Medical and Dental University
  •  Development a novel therapy targeting NETs formation for anti-neutrophil cytoplasmic antibody-associated vasculitis

    • Principal Investigator
      HARIGAI Masayoshi
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      膠原病・アレルギー・感染症内科学
    • Research Institution
      Tokyo Medical and Dental University
  •  The pharmaco-epidemiological study about serious and opportunistic infections under treatment of the biologics and the molecular target medicine.

    • Principal Investigator
      TANAKA Michi
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Medical pharmacy
    • Research Institution
      Tokyo Medical and Dental University
  •  Cannabinoid Receptor 2 as a potential therapeutic target in Rheumatoid Arthritis

    • Principal Investigator
      NANKI Toshihiro
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      膠原病・アレルギー・感染症内科学
    • Research Institution
      Teikyo University
      Tokyo Medical and Dental University
  •  Development of new anti-rheumatic drugs

    • Principal Investigator
      KOHSAKA Hitoshi
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      膠原病・アレルギー・感染症内科学
    • Research Institution
      Tokyo Medical and Dental University
  •  A epidemiological study of long-term safety of biological disease-modifying antirheumatic drugs for patients with rheumatoid arthritis and risk factors for adverse drug reactions.

    • Principal Investigator
      HARIGAI Masayoshi
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Applied pharmacology
    • Research Institution
      Tokyo Medical and Dental University
  •  Effect of fractalkine blockade on vasculitis syndrome

    • Principal Investigator
      NANKI Toshihiro
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      膠原病・アレルギー・感染症内科学
    • Research Institution
      Tokyo Medical and Dental University
  •  TREM-1を標的とした関節炎の新規治療法の開発Principal Investigator

    • Principal Investigator
      宮坂 信之
    • Project Period (FY)
      2008
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      膠原病・アレルギー・感染症内科学
    • Research Institution
      Tokyo Medical and Dental University
  •  Cyclin-dependent kinase 4/6 inhibition for treatment of rheumatoid arthritis

    • Principal Investigator
      KOHSAKA Hitoshi
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      膠原病・アレルギー・感染症内科学
    • Research Institution
      Tokyo Medical and Dental University
  •  Multi-center case series study of lung injury associated with novel drugs for rheumatoid arthritis treatment

    • Principal Investigator
      KOIKE Ryuji
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Applied pharmacology
    • Research Institution
      Tokyo Medical and Dental University
  •  関節リウマチの病態形成へのmicroRNAの関与と治療への応用

    • Principal Investigator
      野々村 美紀
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      膠原病・アレルギー・感染症内科学
    • Research Institution
      Tokyo Medical and Dental University
  •  Indoleamine dioxygenaseを標的とした関節リウマチ新規治療法

    • Principal Investigator
      針谷 正祥
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      膠原病・アレルギー・感染症内科学
    • Research Institution
      Tokyo Medical and Dental University
  •  関節リウマチに対するTNF阻害療法中のニューモシスティス肺炎予防指針の確立

    • Principal Investigator
      KOIKE Ryuji
    • Project Period (FY)
      2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      膠原病・アレルギー・感染症内科学
    • Research Institution
      Tokyo Medical and Dental University
  •  プロテインチップとプロテオーム技術を用いた新自己抗体の網羅的探索

    • Principal Investigator
      上阪 等
    • Project Period (FY)
      2006
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      膠原病・アレルギー・感染症内科学
    • Research Institution
      Tokyo Medical and Dental University
  •  新たな自己免疫筋炎モデルによる多発筋炎・皮膚筋炎の新治療法の開発の試み

    • Principal Investigator
      上阪 等
    • Project Period (FY)
      2005
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      膠原病・アレルギー・感染症内科学
    • Research Institution
      Tokyo Medical and Dental University
  •  New treatment of rheumatoid arthritis

    • Principal Investigator
      KOHSAKA Hitoshi
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      膠原病・アレルギー・感染症内科学
    • Research Institution
      Tokyo Medical and Dental University
  •  ICOS-L遺伝子導入tolerogenic DCを用いた新規関節リウマチ治療法

    • Principal Investigator
      HARIGAI Masayoshi
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      膠原病・アレルギー・感染症内科学
    • Research Institution
      Tokyo Medical and Dental University
  •  Development of chondro-protective and regenerative strategy using alginate-recovered-chondrocyte tissue

    • Principal Investigator
      HARIGAI Masayoshi
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      膠原病・アレルギー・感染症内科学
    • Research Institution
      Tokyo Medical and Dental University
  •  新規ケモカインCXCL16を介する関節リウマチ病態形成の分子機構の解明Principal Investigator

    • Principal Investigator
      宮坂 信之
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      膠原病・アレルギー・感染症内科学
    • Research Institution
      Tokyo Medical and Dental University
  •  Cell cycle regulation for treatment of rheumatoid arthritis

    • Principal Investigator
      KOHSAKA Hitoshi
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      膠原病・アレルギー・感染症内科学
    • Research Institution
      Tokyo Medical and Dental University
  •  成人発症スティル病の診断・治療・予後に関する集学的研究

    • Principal Investigator
      江口 勝美
    • Project Period (FY)
      2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      内科学一般
    • Research Institution
      Nagasaki University
  •  Th1細胞分化とJAK、STATシグナル伝達機構の解析Principal Investigator

    • Principal Investigator
      宮坂 信之
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tokyo Medical and Dental University
  •  遺伝子導入滑膜細胞のシグナル伝達機構の解析―DNAアレイ法との比較検討Principal Investigator

    • Principal Investigator
      宮坂 信之
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      内科学一般
    • Research Institution
      Tokyo Medical and Dental University
  •  シェーグレン症候群診断基準査定調査の企画

    • Principal Investigator
      藤林 孝司
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Surgical dentistry
    • Research Institution
      Dokkyo Medical University
  •  Autoaggressive CD8 T cells in polymyositis

    • Principal Investigator
      KOHSAKA Hitoshi
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      内科学一般
    • Research Institution
      Tokyo Medical & Dental University
  •  Clinical Application of Cell Cycle Control Therapy to Rheumatoid ArthritisPrincipal Investigator

    • Principal Investigator
      MIYASAKA Nobuyuki
    • Project Period (FY)
      2001 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      内科学一般
    • Research Institution
      Tokyo Medical and Dental University
  •  STATによるTh1細胞分化の分子機構-STAT4標的遺伝子の同定Principal Investigator

    • Principal Investigator
      宮坂 信之
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Review Section
      Biological Sciences
    • Research Institution
      Tokyo Medical and Dental University
  •  慢性関節リウマチの細胞回転制御遺伝子誘導療法の実用化に向けた検討Principal Investigator

    • Principal Investigator
      宮坂 信之
    • Project Period (FY)
      2000 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      内科学一般
    • Research Institution
      Tokyo Medical and Dental University
  •  サイクリン依存性キナーゼインヒビター遺伝子導入滑膜細胞のシグナル伝達機構の解析Principal Investigator

    • Principal Investigator
      宮坂 信之
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      内科学一般
    • Research Institution
      Tokyo Medical and Dental University
  •  New Therapy for Rheumatoid Arthritis with Cell Cycle Regulators

    • Principal Investigator
      KOHSAKA Hitoshi
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      内科学一般
    • Research Institution
      Tokyo Medical & Dental University
  •  自己免疫抑制ペプチドの系統的検索

    • Principal Investigator
      上阪 等
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      内科学一般
    • Research Institution
      Tokyo Medical and Dental University
  •  The role of MAdCAM-1 for induction and maintenance of oral tolerance -analysis with animal model of arthritisPrincipal Investigator

    • Principal Investigator
      MIYASAKA Nobuyuki
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      内科学一般
    • Research Institution
      Tokyo Medical and Dental University
  •  慢性関節リウマチ滑膜細胞シグナル伝達機構の解明と人為的制御Principal Investigator

    • Principal Investigator
      宮坂 信之
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      内科学一般
    • Research Institution
      Tokyo Medical and Dental University
  •  Cell Cycle Control for Treatment of Rheumatoid ArthritisPrincipal Investigator

    • Principal Investigator
      MIYASAKA Nobuyuki
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      内科学一般
    • Research Institution
      Tokyo Medical and Dental University
  •  セラミドを介するアポトーシスシグナル伝達経路の分子生物学的解析析-自己免疫疾患病因解析の試みPrincipal Investigator

    • Principal Investigator
      宮坂 信之
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      内科学一般
    • Research Institution
      Tokyo Medical and Dental University
  •  肺線維化プロセスの分子生物学的研究

    • Principal Investigator
      吉澤 靖之
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Tokyo Medical and Dental University
  •  慢性関節リウマチ病変局所におけるシグナル伝達機構の解析:Jak-Stat系の関与Principal Investigator

    • Principal Investigator
      宮坂 信之
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      内科学一般
    • Research Institution
      Tokyo Medical and Dental University
  •  Gene Therapy of Rheumatoid Arthritis

    • Principal Investigator
      KOHSAKA Hitoshi
    • Project Period (FY)
      1996 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      内科学一般
    • Research Institution
      Tokyo Medical and Dental University
  •  特発性肺線維症の病態-慢性鳥飼病との関連

    • Principal Investigator
      吉澤 靖之
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Tokyo Medical and Dental University
  •  自己免疫疾患の寛容誘導療法、遺伝子免疫療法の開発

    • Principal Investigator
      KOHSAKA Hitoshi
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      内科学一般
    • Research Institution
      Tokyo Medical and Dental University
  •  The development of the treatment of autoimmune diseases by cytokine gene transferPrincipal Investigator

    • Principal Investigator
      MIYASAKA Nobuyuki
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      内科学一般
    • Research Institution
      TOKYO MEDICAL & DENTAL UNIVERSITY
  •  Medianisms of stimulation to Th1, Th2 cell in the filarical infection

    • Principal Investigator
      FUJITA Koichiro
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      寄生虫学(含医用動物学)
    • Research Institution
      Tokyo Medical and Dental University
  •  Analysis of lymphoproliferative disorders of Sjogren's syndrome

    • Principal Investigator
      SAITO Ichiro
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      病態科学系歯学(含放射線系歯学)
    • Research Institution
      Tokyo Medical and Dental University
  •  シェーグレン症候群の病因論に関するEBウイルスの分子機構の検討

    • Principal Investigator
      SAITO Ichiro
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      病態科学系歯学(含放射線系歯学)
    • Research Institution
      Tokyo Medical and Dental University
  •  Gene cloning of a novel cytokine inducing ICAM-1Principal Investigator

    • Principal Investigator
      MIYASAKA Nobuyuki
    • Project Period (FY)
      1992 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      内科学一般
    • Research Institution
      Tokyo Medical and Dental University
  •  T細胞ハイブリド-マを用いた慢性関節リウマチにおける免疫制御機構の解析Principal Investigator

    • Principal Investigator
      宮坂 信之
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      内科学一般
    • Research Institution
      Tokyo Women's Medical University
  •  シェーグレン症候群におけるB細胞活性化機構の解析Principal Investigator

    • Principal Investigator
      宮坂 信之
    • Project Period (FY)
      1988 – 1989
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      内科学一般
    • Research Institution
      Tokyo Women's Medical University
  •  シェーグレン症侯群におけるB細胞活性化機構の解析(発癌機構解明の試み)Principal Investigator

    • Principal Investigator
      宮坂 信之
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      内科学一般
    • Research Institution
      Tokyo Women's Medical University
  •  thrombomodulinの理化学的生物学的諸性質ならびに病態生理学的意義

    • Principal Investigator
      青木 延雄
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Tokyo Medical and Dental University

All 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2001 Other

All Journal Article Presentation Patent

  • [Journal Article] CCL18 activates fibroblast-like synoviocytes in patients with rheumatoid arthritis2013

    • Author(s)
      Takayasu A, Miyabe Y, Yokoyama W, Kaneko K, Miyabe C, Fukuda S, Kubota T, Miyasaka N, Nanki T
    • Journal Title

      J. Rheumatol

      Volume: 40 Issue: 6 Pages: 1026-1028

    • DOI

      10.3899/jrheum.121412

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591435
  • [Journal Article] Am80, a retinoic acid receptor agonist, ameliorates murine vasculitis through the suppression of neutrophil migration and activation2013

    • Author(s)
      Miyabe C, Miyabe Y, Miura NN, Takahashi K, Terashima Y, Toda E, Honda F, Morio T, Yamagata N, Ohno N, Shudo K, Suzuki J, Isobe M, Matsushima K, Tsuboi R, Miyasaka N, Nanki T
    • Journal Title

      Arthritis Rheum

      Volume: 65 Issue: 2 Pages: 503-512

    • DOI

      10.1002/art.37784

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591435, KAKENHI-PROJECT-23659518, KAKENHI-PROJECT-25670472
  • [Journal Article] Association of IRF5 polymorphism with MPO-ANCA positive vasculitis in a Japanese population2013

    • Author(s)
      Kawasaki A, Inoue N, Ajimi C, Sada K, Kobayashi S,Yamada H, Furukawa H, Sumida T, Tohma S, Miyasaka N, Matsuo S, Ozaki S, Hashimoto H, Makino H, Harigai M, Tsuchiya N.
    • Journal Title

      Genes Immun

      Volume: 14(8) Pages: 527-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659472
  • [Journal Article] Suppression of elevations in serum C reactive protein levels by anti-IL-6 autoantibodies in two patients with severe bacterial infections2013

    • Author(s)
      Nanki T, Onoue I, Nagasaka K, Takayasu A, Ebisawa M, Hosoya T, Shirai T, Sugihara T, Hirata S, Kubota T, Harigai M, Miyasaka N
    • Journal Title

      Ann. Rheum. Dis

      Volume: 72 Issue: 6 Pages: 1100-1102

    • DOI

      10.1136/annrheumdis-2012-202768

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591435, KAKENHI-PROJECT-23791109, KAKENHI-PROJECT-25461499
  • [Journal Article] Clinical characteristics and risk factors for Pneumocystis jirovecii pneumonia in patients with rheumatoid arthritis receiving adalimumab : a retrospective review and case-control study of 17 patients2013

    • Author(s)
      Watanabe K, Sakai R, Koike R, Sakai F, Sugiyama H, Tanaka M, Komano Y, Akiyama Y, Mimura T, Kaneko M, Tokuda H, Iso T, Motegi M, Ikeda K, Nakajima H, Taki H, Kubota T, Kodama H, Sugii S, Kuroiwa T, Nawata Y, Shiozawa K, Ogata A, Sawada S, Matsukawa Y, Okazaki T, Mukai M, Iwahashi M, Saito K, Tanaka Y, Nanki T, Miyasaka N, Harigai M
    • Journal Title

      Mod Rheumatol

      Volume: 23(6) Pages: 1085-93

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590171
  • [Journal Article] Necessity of Lysophosphatidic Acid Receptor 1 for Development of Arthritis2013

    • Author(s)
      Miyabe Y, Miyabe C, Iwai Y, Takayasu A, Fukuda S, Yokoyama W, Nagai J, Jona M, Tokuhara Y, Ohkawa R, Albers HM, Ovaa H, Aoki J, Chun J, Yatomi Y, Ueda H, Miyasaka M, Miyasaka N, Nanki T
    • Journal Title

      Arthritis Rheum

      Volume: 65 Issue: 8 Pages: 2037-2047

    • DOI

      10.1002/art.37991

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591435, KAKENHI-ORGANIZER-24111001, KAKENHI-PLANNED-24111005, KAKENHI-PROJECT-24790576
  • [Journal Article] Serum level of soluble CX3CL1/fractalkine is elevated in patients with polymyositis and dermatomyositis, which is correlated with disease activity2012

    • Author(s)
      Suzuki F, Kubota T, Miyazaki Y, Ishikawa K, Ebisawa M, Hirohata S, Ogura T, Mizusawa H, Imai T, Miyasaka N, Nanki T
    • Journal Title

      Arthritis Res. Ther

      Volume: 14 Issue: 2

    • DOI

      10.1186/ar3761

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591435, KAKENHI-PROJECT-23591447
  • [Journal Article] Arthritic joint-targeting small interfering RNA-encapsulated liposome : Implication for treatment strategy for rheumatoid arthritis2012

    • Author(s)
      Komano Y, Yagi N, Onoue I, Kaneko K, Miyasaka N, Nanki T
    • Journal Title

      J. Pharmacol. Exp. Ther

      Volume: 340 Issue: 1 Pages: 109-113

    • DOI

      10.1124/jpet.111.185884

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591435
  • [Journal Article] Chemerin activates fibroblast-like synoviocytes in patients with rheumatoid arthritis2011

    • Author(s)
      Kayoko Kaneko, et al
    • Journal Title

      Arthritis Res Ther

      Volume: 13 Issue: 5

    • DOI

      10.1186/ar3475

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19059004, KAKENHI-PROJECT-23591435
  • [Journal Article] Therapeutic effect of D1-like dopamine receptor antagonist on collagen-induced arthritis of mice2011

    • Author(s)
      Nakashioya H, Nakano K, Watanabe N, Miyasaka N, Matsushita S, Kohsaka H
    • Journal Title

      Mod Rheumatol

      Volume: 23 Pages: 177-183

    • NAID

      10029362184

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249060
  • [Journal Article] Addition of the collagen binding domain of fibronectin potentiates the biochemical availability of hepatocyte growth factor for cutaneous wound healing2011

    • Author(s)
      Okiyama N, Kitajima T, Ito Y, Yokozeki H, Miyasaka N, Kohsaka H
    • Journal Title

      J Dermatol Sci

      Volume: 61 Pages: 215-217

    • NAID

      10030890602

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249060
  • [Journal Article] Anti-arthritic effect of E3 ubiquitin ligase, c-MIR, expression in the joints2011

    • Author(s)
      Toyomoto M, Ishido S, Miyasaka N, Sugimoto H, Kohsaka H
    • Journal Title

      Int Immunol

      Volume: 23 Pages: 215-217

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249060
  • [Journal Article] The effect of synthetic retinoid, Am80, on T helper cell development and antibody production in murine collagen-induced arthritis.2010

    • Author(s)
      Sato A, Watanabe K, Kaneko K, Murakami Y, Ishido M, Miyasaka N, Nanki T.
    • Journal Title

      Mod.Rheumatol. 20

      Pages: 244-244

    • NAID

      10027169254

    • Data Source
      KAKENHI-PROJECT-20591166
  • [Journal Article] Expression of CD45 isoforms correlates with differential proliferative responses of peripheral CD4+ and CD8+ T cells2010

    • Author(s)
      Seki I, Suzuki M, Miyasaka, N, Kohsaka H
    • Journal Title

      Immunol Lett

      Volume: 129 Pages: 39-46

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249060
  • [Journal Article] Pathogenic role of CXCR7 in rheumatoid arthritis.2010

    • Author(s)
      Watanabe K, Penfold MET, Matsuda A, Ohyanagi N, Kaneko K, Miyabe Y, Matsumoto K, Schall TJ, Miyasaka N, Nanki T.
    • Journal Title

      Arthritis Rheum. 62

      Pages: 3211-3211

    • Data Source
      KAKENHI-PROJECT-20591166
  • [Journal Article] Intervention of an Inflammation Amplifier, Triggering Receptor Expressed on Myeloid Cells 1, for Treatment of Autoimmune Arthritis.2009

    • Author(s)
      Murakami Y, 他3名, Miyasaka N, Kohsaka H.
    • Journal Title

      Arthritis Rheum 60

      Pages: 1615-1623

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249060
  • [Journal Article] Hypoxia-induced abrogation of contact-dependent inhibition of rheumatoid arthritis synovial fibroblast proliferation.2009

    • Author(s)
      Nonomura Y, Mizoguchi F, Suzuki A, Nanki T, Kato H, Miyasaka N, Kohsaka H.
    • Journal Title

      J.Rheumatol. 36

      Pages: 698-698

    • Data Source
      KAKENHI-PROJECT-20591166
  • [Journal Article] Retinoid ameliorates experimental autoimmune myositis, with modulation of Th cell differentiation and antibody production in vivo.2009

    • Author(s)
      Ohyanagi N, Ishido M, Suzuki F, Kaneko K, Kubota T, Miyasaka N, Nanki T.
    • Journal Title

      Arthritis Rheum. 60

      Pages: 3118-3118

    • Data Source
      KAKENHI-PROJECT-20591166
  • [Journal Article] Hypoxia-induced Abrogation of Contact-dependent Inhibition of Rheumatoid Arthritis Synovial Fibroblast Proliferation2009

    • Author(s)
      Nonomura Y, Mizoguchi F, Suzuki A, Nanki T, Kato H, Miyasaka N, Kohsaka H.
    • Journal Title

      J Rheumatol 36

      Pages: 698-705

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390272
  • [Journal Article] Japan College of Rheumatology 2009 guidelines for the use of tocilizumab, a humanized anti-interleukin-6 receptor monoclonal antibody, in rheumatoid arthritis2009

    • Author(s)
      Koike R, Harigai M, Atsumi T, Amano K, Kawai S, Saito K, Saito T, Yamamura M, Matsubara T, Miyasaka N.
    • Journal Title

      Mod Rheumatol 19

      Pages: 351-7

    • NAID

      10025113303

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590530
  • [Journal Article] Hypoxia-induced Abrogation of Contact-dependent Inhibition of Rheumatoid Arthritis Synovial Fibroblast Proliferation2009

    • Author(s)
      Nonomura Y, Mizoguchi F, Suzuki A, Nanki T, Kato H, Miyasaka N, Kohsaka H
    • Journal Title

      J Rheumatol 36(4)

      Pages: 698-705

    • Data Source
      KAKENHI-PROJECT-19390272
  • [Journal Article] Expression of CD45 isoforms correlates with differential proliferative responses of peripheral CD4+ and CD8+ T cells2009

    • Author(s)
      Seki I, Suzuki M, Miyasaka, N, Kohsaka H.
    • Journal Title

      Immunol Lett 129

      Pages: 39-46

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249060
  • [Journal Article] Possible involvement of chemokine-induced platelet activation in thrombophilic diathesis of antiphospholipid syndrome: an attractive target for the NF-kB-specific inhibitor DHMEQ.2009

    • Author(s)
      Kubota T, Fukuya Y, Hashimoto R, Kanda T, Suzuki H, Okamura Y, Nanki T, Miyasaka N, Umezawa K.
    • Journal Title

      Ann.N.Y.Acad.Sci. 1173

      Pages: 137-145

    • Data Source
      KAKENHI-PROJECT-20591166
  • [Journal Article] Japan College of Rheumatology 2009 guidelines for the use of to cilizumab, a humanized anti-interleukin-6 receptor monoclonal antibody, in rheumatoid arthritis.2009

    • Author(s)
      Koike R, 針谷正祥, Atsumi T, Amano K, Kawai S, Saito K, Saito T, Yamamura M, Matsubara T, Miyasaka N.
    • Journal Title

      Modern Rheumatology 19

      Pages: 351-357

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390158
  • [Journal Article] Hypoxia-induced Abrogation of Contact-dependent Inhibition of Rheumatoid Arthritis Synovial Fibroblast Proliferation2009

    • Author(s)
      Nonomura Y, Mizoguchi F, 他3名, Miyasaka N, Kohsaka H
    • Journal Title

      J Rheumatol 36

      Pages: 698-705

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249060
  • [Journal Article] Chemokine receptor expression and functional effects of chemokines on B cells: Implication in the pathogenesis of rheumatoid arthritis.2009

    • Author(s)
      Nanki T, Takada K, Komano Y, Morio T, Kanegane H, Nakajima A, Lipsky PE, Miyasaka N.
    • Journal Title

      Arthritis Res.Ther. 11

    • Data Source
      KAKENHI-PROJECT-20591166
  • [Journal Article] CHANGE Study Investigators Clinical investigation in highly disease-affected rheumatoid arthritis patients in Japan with adalimumab applying standard and general evaluation : the CHANGE study2008

    • Author(s)
      Miyasaka N
    • Journal Title

      Mod Rheumatol 18

      Pages: 252-62

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590530
  • [Journal Article] Successful treatment of animal models of rheumatoid arthritis with smallmolecule cyclin-dependent kinase inhibitors.2008

    • Author(s)
      Sekine C, Sugihara T, Miyake S, Hirai H, Yoshida M, Miyasaka N, Kohsaka H
    • Journal Title

      J Immunol 180

      Pages: 1954-1961

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390272
  • [Journal Article] Excessive Production of IFN-γ in Patients with Systemic Lupus Erythematosus and Its Contribution to Induction of B Lymphocyte Stimulator/B Cell-Activating Factor/TNF Ligand SuperfamilY-13B2008

    • Author(s)
      Harigai M. Kawamoto M, Hara M, Kubota T, Kamatani N, Miyasaka N
    • Journal Title

      The Journal of Immunology 181

      Pages: 2211-2219

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659251
  • [Journal Article] Clinical investigation in highly disease-affeeted rheumatoid arthritis patients in Japan with adalimumab applying standard and general evaluation.2008

    • Author(s)
      Miyasaka N, et al.
    • Journal Title

      Modern Rheumatology 18

      Pages: 252-262

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590530
  • [Journal Article] Successful treatment of animal models of rheumatoid arthritis with smallmolecule cyclin-dependent kinase inhibitors2008

    • Author(s)
      Sekine C, Sugihara T, Miyake S, Hirai H,Yoshida M, Miyasaka N, Kohsaka H
    • Journal Title

      J Immuno 180(3)

      Pages: 1954-61

    • Data Source
      KAKENHI-PROJECT-19390272
  • [Journal Article] Pneumocystis Pneumonia Associated with Infliximab in Japan2007

    • Author(s)
      Harigai M, Koike R, Miyasaka N, et. al.
    • Journal Title

      N Engl J Med 357

      Pages: 1874-1876

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659251
  • [Journal Article] Pneumocystis pneumonia associated with infliximab in Japan.2007

    • Author(s)
      Harigai M, Koike R, Miyasaka N
    • Journal Title

      New England Journal of Medicine 357

      Pages: 1874-1876

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590530
  • [Journal Article] A new murine model to define critical pathologic and therapeutic of polymyositis2007

    • Author(s)
      1. Sugihara T, Sekine C, Nakae T, Kohyama K, Harigai M, Iwakura Y, Matsumoto Y, Miyasaka N, Kohsaka H.
    • Journal Title

      Arthritis Rheum. 56

      Pages: 1304-1314

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591159
  • [Journal Article] Pneumocystis pneumonia associated with infliximab in Japan2007

    • Author(s)
      Harigai M, Koike R, Miyasaka N.
    • Journal Title

      N Engl J Med 357

      Pages: 1874-6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590530
  • [Journal Article] A new murine model to define critical pathologic and therapeutic of polymyositis2007

    • Author(s)
      Sugihara T, Sekine C, Nakae T, Kohyama K,Harigai M, Iwakura Y, Matsumoto Y, MiyasakaN, and Kohsaka H
    • Journal Title

      Arthritis Rheum 56(4)

      Pages: 1304-1314

    • Data Source
      KAKENHI-PROJECT-19390272
  • [Journal Article] Update on the Japanese guidelines for the use of infliximab and etanercept in rheumatoid arthritis2007

    • Author(s)
      Koike R, Takeuchi T, Eguchi K, Miyasaka N.
    • Journal Title

      Mod Rheumatol 17

      Pages: 451-8

    • NAID

      10020177958

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590530
  • [Journal Article] 関節リウマチに対する生物学的製剤の使用ガイドライン2006

    • Author(s)
      小池竜司, 宮坂信之
    • Journal Title

      リウマチ科 35・5

      Pages: 413-421

    • Data Source
      KAKENHI-PROJECT-18639010
  • [Journal Article] Cyclin-dependent kinase 4/6 directly modulates expression of rheumatoid inflammatory mediators in retinoblastoma protein-dependent and independent pathways2006

    • Author(s)
      Nonomura Y, Nagasaka K, Hagiyama H, Sekine C, Nanki T, Tamamori-Adachi M, Miyasaka, N, Kohsaka H
    • Journal Title

      Arthritis Rheum 54(7)

      Pages: 2074-2083

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390289
  • [Journal Article] Chondroprotective effects of human bone morphogenic protein-7 in alginate-recovered-chondrocyte tissue2006

    • Author(s)
      Masayoshi Harigai, Koichi Masuda, Nobuyuki Miyasaka
    • Journal Title

      Arthritis Rheum 53(suppl)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390286
  • [Journal Article] Chondroprotective effects of human bone morphogenic protein-7 in alginate-recovered-chondrocyte tissue2006

    • Author(s)
      Masayoshi Harigai, Koichi Masuda, Nobuyuki Miyasaka
    • Journal Title

      Arthritis Rheum Vol. 53 Suppl (In press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390286
  • [Journal Article] 生物学的製剤を安全に使用するために2006

    • Author(s)
      宮坂信之, 小池竜司, 針谷正祥
    • Journal Title

      整形・災害外科 49・6

      Pages: 695-704

    • Data Source
      KAKENHI-PROJECT-18639010
  • [Journal Article] Inhibition of CX3CL1(Fractalkine) improves experimental autoimmune myositis in SJL/J mice.2005

    • Author(s)
      Suzuki F., Nanki T., Imai T., Kikuchi H., Hirohata S., Kohsaka H., Miyasaka N.
    • Journal Title

      J.Immunol 175(10)

      Pages: 6987-6996

    • Data Source
      KAKENHI-PROJECT-13854014
  • [Journal Article] Pathogenic role of the CXCL16-CXCR6 pathway in rheumatoid arthritis2005

    • Author(s)
      Nanki T., Shimaoka T., Hayashida K., Taniguchi K., Yonehara S., Miyasaka N.
    • Journal Title

      Arthritis Rheum. 52(10)

      Pages: 3004-3014

    • Data Source
      KAKENHI-PROJECT-13854014
  • [Journal Article] Effect of a small molecule inhibitor of nuclear factor-κB nuclear translocation in a murine model of arthritis and cultured human synovia cells.2005

    • Author(s)
      Wakamatsu K., Nanki T., Miyasaka N., Umezawa K., Kubota T.
    • Journal Title

      Arthritis Res.Ther. 7(6)

    • Data Source
      KAKENHI-PROJECT-13854014
  • [Journal Article] Inhibition of CX3CL1 (fractalkine) improves experimental autoimmune myositis in SJL/J mice.2005

    • Author(s)
      Suzuki F, Nanki T, Imai T, Kikuchi H, Hirohata S, Kohsaka H, Miyasaka N
    • Journal Title

      J Immunol 175(10)

      Pages: 6987-6996

    • Data Source
      KAKENHI-PROJECT-17659299
  • [Journal Article] Adenoviral gene delivery to alginate-recovered-chondrocyte tissue2005

    • Author(s)
      Masayoshi Harigai, Koichi Masuda, Nobuyuki Miyasaka
    • Journal Title

      Modern Rheumatol 15(suppl)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390286
  • [Journal Article] Inhibition of CX3CL1 (fractalkine) improves experimental autoimmune myositis in SJL/J mice.2005

    • Author(s)
      Suzuki F, Nanki T, Imai T, Kikuchi H, Hirohata S, Kohsaka H, Miyasaka N.
    • Journal Title

      J Immunol 175(10)

      Pages: 6987-6996

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390289
  • [Journal Article] Adenoviral gene delivery to alginate-recovered-chondrocyte tissue2005

    • Author(s)
      Masayoshi Harigai, Koichi Masuda, Nobuyuki Miyasaka
    • Journal Title

      Modern Rheumatology Vol. 15, Suppl

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390286
  • [Journal Article] Inhibition of CX3CL1 (fractalkine) improves experimental autoimmune myositis in SJL/J mice.2005

    • Author(s)
      Suzuki F, Nanki T, Imai T, Kikuchi H, Hirohata S, Kohsaka H, Miyasaka N
    • Journal Title

      J Immunol 175(10)

      Pages: 6987-6996

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390289
  • [Journal Article] Development of TCRB CDR3 length repertoire of humanlymphocytes.2004

    • Author(s)
      Nishio J, Suzuki M, Nanki T, Miyasaka N, Kohsaka H
    • Journal Title

      Int Immunol 175.10

      Pages: 423-431

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390311
  • [Journal Article] Development of TCRB CDR3 length repertoire of human lymphocytes2004

    • Author(s)
      Nishio J, Suzuki M, Nanki T, Miyasaka N, Kohsaka H.
    • Journal Title

      Int Immunol 16(3)

      Pages: 423-431

    • Data Source
      KAKENHI-PROJECT-13854014
  • [Journal Article] Development of TCRB CDR3 length repertoire of human lymphocytes2004

    • Author(s)
      Nishio J, Suzuki M, Nanki T, Miyasaka N, Kohsaka H.
    • Journal Title

      Int Immunol 16(3)

      Pages: 423-431

    • Data Source
      KAKENHI-PROJECT-15390311
  • [Journal Article] Treatment of rheumatoid arthritis with humanized anti-interleukin-6 receptor antibody : a multicenter, double-blind, placebo-controlled trial.2004

    • Author(s)
      Nishimoto N, Yoshizaki K, Miyasaka N, Yamamoto K, Kawai S, Takeuchi T, Hashimoto J, Azuma J, Kishimoto T
    • Journal Title

      Arthritis Rheum. 50(6)

      Pages: 1761-1769

    • Data Source
      KAKENHI-PROJECT-15659235
  • [Journal Article] Inhibition of fractalkine ameliorates murine collagen-induced arthritis.2004

    • Author(s)
      Nanki T, Urasaki Y, Imai T, Nishimura M, Muramoto K, Kubota T, Miyasaka N
    • Journal Title

      J.Immunol. 173(11)

      Pages: 7010-7016

    • Data Source
      KAKENHI-PROJECT-15659235
  • [Journal Article] Development of TCRB CDR3 length repertoire of human lymphocytes2004

    • Author(s)
      Nishio J, Suzuki M, Nanki T, Miyasaka N, Kohsaka H
    • Journal Title

      Int Immunol 16(3)

      Pages: 423-431

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390311
  • [Journal Article] Development of TCRB CDR3 length repertoire of human T lymphocytes.2004

    • Author(s)
      Nishio J, Suzuki M, Nanki T, Miyasaka N, Kohsaka H
    • Journal Title

      Int.Immunol. 16(3)

      Pages: 423-431

    • NAID

      10013084180

    • Data Source
      KAKENHI-PROJECT-15659235
  • [Journal Article] Gene transfer of a cell cycle modulator exerts anti-inflammatory effects in the treatment of arthritis.2003

    • Author(s)
      Nonomura Y, Kohsaka H, Nagasaka K, Miyasaka N.
    • Journal Title

      J.Immunol 171(9)

      Pages: 4913-4919

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13854014
  • [Journal Article] Gene transfer of a cell cycle modulator exerts anti-inflammatory effects in the treatment of arthritis.2003

    • Author(s)
      Nonomura Y, Kohsaka H, Nagasaka K, Miyasaka N
    • Journal Title

      J Immunol 171(9)

      Pages: 4913-4919

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13854014
  • [Journal Article] Suppression of arthritis by forced expression of cyclin-dependent kinase Inhibitor p21^<Cip1> gene into the joints.2001

    • Author(s)
      Nonomura Y, Kohsaka H, Nasu K, Terada Y, Ikeda M, Miyasaka N.
    • Journal Title

      Int Immunol 13(6)

      Pages: 723-731

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13854014
  • [Journal Article] Suppression of arthritis by forced expression of cyclin-dependent kinase Inhibitor p21^<Cipl> gene into the joints.2001

    • Author(s)
      Nonomura Y, Kohsaka H, Nasu K, Terada Y, Ikeda M, Miyasaka N
    • Journal Title

      Int Immunol 13(6)

      Pages: 723-731

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13854014
  • [Journal Article] Cyclin-dependent kinase 4/6 directly modulates expression of rheumatoi inflammatory mediators in retinoblastoma protein-dependent and independent pathways

    • Author(s)
      Nonomura Y, Nagasaka K, Hagiyama H, Sekine C, Nanki T, Tamamori-Adachi M, Miyasaka N, Kohsaka N.
    • Journal Title

      Arthritis Rheum. in press

    • Data Source
      KAKENHI-PROJECT-13854014
  • [Journal Article] Cyclin-dependent kinase 4/6 directly modulates expression of rheumatoid inflammatory mediators in retinoblastoma protein-dependent and independent pathways

    • Author(s)
      Y Nonomura, K Nagasaka, H Hagiyama, C Sekine, T Nanki, M Tamamori-Adachi, N Miyasaka, H Kohsaka
    • Journal Title

      Arthritis and Rheumatism (In press)

    • Data Source
      KAKENHI-PROJECT-17390289
  • [Journal Article] Cyclin-dependent kinase 4/6 directly modulates expression of rheumatoid inflammatory mediators in retinoblastoma protein-dependent and independent pathways

    • Author(s)
      Nonomura Y, Nagasaka K, Hagiyama H, Sekine C, Nanki T, Tamamori-Adachi M, Miyasaka N, Kohsaka H
    • Journal Title

      Arthritis Rheum (in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13854014
  • [Journal Article] Methotrexate and trimethoprim-sulfamethoxazole use for PCP prophylaxis.

    • Author(s)
      Yamazaki H, Nanki T, Miyasaka N, Harigai, M.
    • Journal Title

      J Rheumatol in press.

    • Data Source
      KAKENHI-PROJECT-20390158
  • [Journal Article] Cyclin-dependent kinase 4/6 directly modulates expression of rheumatoid inflammatory mediators in retinoblastoma protein-dependent and independent pathways

    • Author(s)
      Nonomura Y, Nagasaka K, Hagiyama H, Sekine C, Nanki T, Tamamori-Adachi M, Miyasaka N, Kohsaka H.
    • Journal Title

      Arthritis Rheum. (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13854014
  • [Patent] 抗関節リウマチ活性を有する物質のスクリーニング方法及び評価方法2006

    • Inventor(s)
      上阪 等, 宮坂 信之
    • Industrial Property Rights Holder
      医科歯科, 理研
    • Filing Date
      2006-02-20
    • Data Source
      KAKENHI-PROJECT-17390289
  • [Patent] 抗関節リウマチ活性を有する物質のスクリーニング方法及び評価方法。2006

    • Inventor(s)
      宮坂信之, 上阪 等
    • Industrial Property Rights Holder
      東京医科歯科大学 理化学研究所
    • Filing Date
      2006-02-20
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13854014
  • [Patent] 滑膜増殖抑制剤2005

    • Inventor(s)
      上阪 等, 宮坂 信之
    • Industrial Property Rights Holder
      医科歯科, 理研
    • Filing Date
      2005-07-18
    • Data Source
      KAKENHI-PROJECT-17390289
  • [Patent] 滑膜細胞増殖抑制剤2005

    • Inventor(s)
      宮坂信之, 上阪 等
    • Industrial Property Rights Holder
      東京医科歯科大学 理化学研究所
    • Filing Date
      2005-07-18
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13854014
  • [Presentation] 膠原病における免疫抑制療法下の肺感染症に関する前向き研究2013

    • Author(s)
      山崎隼人、酒井良子、小池竜司、田中みち、南木敏宏、渡部香織、宮坂信之、針谷正祥
    • Organizer
      第57回日本リウマチ学会総会・学術集会
    • Place of Presentation
      京都(国立京都国際会館)
    • Data Source
      KAKENHI-PROJECT-23590171
  • [Presentation] リゾフォスファチジン酸受容体1(LPA_1)欠損による関節炎抑制2013

    • Author(s)
      宮部斉重、宮部千恵、福田真、横山和佳、宮坂信之、南木敏宏
    • Organizer
      第57回日本リウマチ学会総会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-23591435
  • [Presentation] Lysophosphatidic acid receptor LPA_1 is essential for development of arthritis2013

    • Author(s)
      Miyabe Y, Miyabe C, Iwai Y, Takayasu A, Fukuda S, Yokoyama W, Nagai J, Jona M, Tokuhara Y, Ohkawa R, Albers HM, Ovaa H, Aoki J, Chun J, Yatomi Y, Ueda H, Miyasaka M, Miyasaka N, Nanki T
    • Organizer
      ヨーロッパリウマチ学会
    • Place of Presentation
      マドリード
    • Data Source
      KAKENHI-PROJECT-23591435
  • [Presentation] Am80によるCandida albicans water-soluble fraction誘導血管炎の抑制効果2012

    • Author(s)
      宮部千恵、宮部斉重、大野尚仁、高橋啓、宮坂信之、南木敏宏
    • Organizer
      第56回日本リウマチ学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23591435
  • [Presentation] Am80 ameliorates murine model of vasculitis via suppression of neutrophil and endothelial cell activation2012

    • Author(s)
      Miyabe C, Miyabe Y, Miura NN, Takahashi K, Terashima Y, Morio T, Ohno N, Shudo K, Yamagata N, Suzuki K, Suzuki J, Matsushima K, Tsuboi R, Miyasaka N, Nanki T
    • Organizer
      The Asia Pacific Meeting of Vasculitis and ANCA Workshop
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23591435
  • [Presentation] CCL18による関節リウマチ線維芽細胞様滑膜細胞の活性化2012

    • Author(s)
      髙安愛子、宮部斉重、金子佳代子、宮部千恵、横山和佳、福田真、窪田哲朗、宮坂信之、南木敏宏
    • Organizer
      第56回日本リウマチ学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23591435
  • [Presentation] Anti-IL-6 autoantibody inhibited elevation of serum C-reactive protein level in two patients with severe bacterial infection2012

    • Author(s)
      Nanki T, Onoue I, Nagasaka K, Hirata S, Hosoya T, Ebisawa M, Sugihara T, Harigai M, Miyasaka N
    • Organizer
      ヨーロッパリウマチ学会
    • Place of Presentation
      ベルリン
    • Data Source
      KAKENHI-PROJECT-23591435
  • [Presentation] Autotaxin and Lysophosphatidic Acid Receptors : Potential Target Molecules in New Therapies for Rheumatoid Arthritis2012

    • Author(s)
      Miyabe Y, Miyabe C, Iwai Y, Ebisawa M, Miyasaka M, Miyasaka N, Nanki T
    • Organizer
      Keystone Symposia, Chemokines and Leukocyte Trafficking in Homeostasis and Inflammation
    • Place of Presentation
      Breckenridge, USA
    • Data Source
      KAKENHI-PROJECT-23591435
  • [Presentation] カンナビノイドによる関節炎抑制作用2012

    • Author(s)
      福田真、高安愛子、横山和佳、宮部千恵、宮部斉重、宮坂信之、南木敏宏
    • Organizer
      第56回日本リウマチ学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23591435
  • [Presentation] 関節リウマチの病態形成におけるCCL25/CCR9相互作用の関与2012

    • Author(s)
      横山和佳、金子佳代子、高安愛子、福田真、宮部斉重、宮部千恵、宮坂信之、南木敏宏
    • Organizer
      第56回日本リウマチ学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23591435
  • [Presentation] Am80, a retinoic acid receptor agonist, ameliorates murine vasculitis through the suppression of neutrophil migration and activation2012

    • Author(s)
      Miyabe C, Miyabe Y, Miura N, Takahashi K, Terashima Y, Toda E, Honda F, Morio T, Yamagata N, Ohno N, Shudo K, Suzuki J, Isobe M, Matsushima K, Tsuboi R, Miyasaka N, Nanki T
    • Organizer
      第76回アメリカリウマチ学会
    • Place of Presentation
      ワシントンDC
    • Data Source
      KAKENHI-PROJECT-23591435
  • [Presentation] オートタキシン/リゾフォスファチジン酸受容体を標的とした関節リウマチの新規治療法開発2012

    • Author(s)
      宮部斉重、宮部千恵、高安愛子、福田真、横山和佳、宮坂信之、南木敏宏
    • Organizer
      第56回日本リウマチ学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23591435
  • [Presentation] アダリムマブ使用関節リウマチ患者におけるニューモシスチス肺炎2011

    • Author(s)
      渡部香織、小池竜司、酒井良子、田中みち、山崎隼人、駒野有希子、南木敏宏、宮坂信之、針谷正祥
    • Organizer
      第39回日本臨床免疫学会
    • Place of Presentation
      東京都
    • Data Source
      KAKENHI-PROJECT-23590171
  • [Presentation] リゾフォスファチジン酸を標的とした関節リウマチの新規治療法開発2011

    • Author(s)
      宮部斉重、福田真、金子佳代子、宮坂信之、南木敏宏
    • Organizer
      第55回日本リウマチ学会総会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-23591435
  • [Presentation] オートタキシン、リゾフォスファチジン酸受容体を標的とした関節リウマチの新規治療法開発2011

    • Author(s)
      宮部斉重、宮部千恵、岩井佳子、海老澤昌史、宮坂昌之、宮坂信之、南木敏宏
    • Organizer
      第40回日本免疫学会総会
    • Place of Presentation
      千葉
    • Data Source
      KAKENHI-PROJECT-23591435
  • [Presentation] TREM-1リガンドの同定とモノクローナル抗体による新規関節炎治療法の開発2011

    • Author(s)
      岩井秀之、細矢匡、村上洋介、宮坂信之、上阪等
    • Organizer
      第39回日本臨床免疫学会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-21249060
  • [Presentation] Identification of TREM-1 ligand and development of new anti-rheumatic therapies with monoclonal antibody2011

    • Author(s)
      Hideyuki Iwai, Tadashi Hosoya, Yousuke Murakami, Nobuyuki Miyasaka, Hitoshi Kohsaka
    • Organizer
      East Asian Group of Rheumatology Meeting
    • Place of Presentation
      Tokyo
    • Year and Date
      2011-10-15
    • Data Source
      KAKENHI-PROJECT-21249060
  • [Presentation] リウマチ治療の新戦略を求めて2011

    • Author(s)
      上阪等、細矢匡、岩井秀之、村上洋介、宮坂信之
    • Organizer
      第39回日本臨床免疫学会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-21249060
  • [Presentation] 関節リウマチのサイクリン依存症キナーゼ4/6阻害療法2011

    • Author(s)
      上阪等、細矢匡、岩井秀之、宮坂信之
    • Organizer
      第55回日本リウマチ学会学術集会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-21249060
  • [Presentation] 合成レチノイドAm80はCandida albicans water-soluble fraction誘導血管炎を抑制する2011

    • Author(s)
      宮部千恵、宮部斉重、三浦典子、高橋啓、寺島裕也、大野尚仁、森尾友宏、松島綱治、宮坂信之、南木敏宏
    • Organizer
      第40回日本免疫学会総会
    • Place of Presentation
      千葉
    • Data Source
      KAKENHI-PROJECT-23591435
  • [Presentation] 関節炎治療標的としてのB細胞上のTREM-1リガンドの同定2011

    • Author(s)
      岩井秀之、細矢匡、村上洋介、宮坂信之、上阪等
    • Organizer
      第40回日本免疫学会学術集会
    • Place of Presentation
      幕張
    • Data Source
      KAKENHI-PROJECT-21249060
  • [Presentation] Chemerin Activates Fibroblast-like Synoviocytes in Patients with Rheumatoid Arthritis2011

    • Author(s)
      Kaneko K, Miyabe Y, Takayasu A, Fukuda S, Miyabe C, Ebisawa M, Yokoyama W, Watanabe K, Imai T, Muramoto K, Terashima Y, Sugihara T, Matsushima K, Miyasaka N, Nanki T
    • Organizer
      第75回アメリカリウマチ学会
    • Place of Presentation
      シカゴ
    • Data Source
      KAKENHI-PROJECT-23591435
  • [Presentation] Chemerin and ChemR23 Expression in Rheumatoid Arthritis:The Therapeutic Implication of the Pathway.2010

    • Author(s)
      金子佳代子, 渡部香織, 宮坂信之, 南木敏宏
    • Organizer
      第14回国際免疫学会
    • Data Source
      KAKENHI-PROJECT-20591166
  • [Presentation] p16INK4a exerts anti-inflammatory effects through acceleration of IRAK1 degradation in macrophages2010

    • Author(s)
      Hitoshi Kohsaka, Yousuke Murakami, Fumitaka Mizoguchi, Nobuyuki Miyasaka
    • Organizer
      14th International Congress of Immunology
    • Place of Presentation
      Osaka
    • Data Source
      KAKENHI-PROJECT-21249060
  • [Presentation] サイクリン依存性キナーゼ阻害薬2010

    • Author(s)
      上阪等、村上洋介、宮坂信之
    • Organizer
      第31回日本炎症・再生医学会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-21249060
  • [Presentation] miR-31 contributes to the optimal bone resorption by osteoclasts2010

    • Author(s)
      Fumitaka Mizoguchi, Yousuke Murakami, Nobuyuki Miyasaka, Hitoshi Kohsaka
    • Organizer
      3^<rd> International Conference on Osteoimmunology
    • Place of Presentation
      Santorini
    • Data Source
      KAKENHI-PROJECT-21249060
  • [Presentation] Pneumocystis jiroveci pneumonia associated with etanercept in patients with rheumatoid arthritis2009

    • Author(s)
      Tanaka M, Sakai R, Koike R, Komano Y, Nanki T, Miyasaka N, Harigai M.
    • Organizer
      Annual European Congress of Rheumatology EULAR
    • Place of Presentation
      Copenhagen, Denmark
    • Data Source
      KAKENHI-PROJECT-19590530
  • [Presentation] 関節リウマチの病態形成におけるCXCR7 の役割に ついて2009

    • Author(s)
      渡部香織, 南木敏宏, 金子佳代子, 宮坂信之
    • Organizer
      第53回日本リウマチ学会総会
    • Data Source
      KAKENHI-PROJECT-20591166
  • [Presentation] Retinoid ameliorates collagen-induced arthritis with modulating Th cell development and antibody production.Keystone symposia2009

    • Author(s)
      Nanki T, Sato A, Watanabe K, Kaneko K, Ishido M, Miyasaka N
    • Organizer
      TH17 Cells in Health and Disease.
    • Data Source
      KAKENHI-PROJECT-20591166
  • [Presentation] Pathogenic Role of CXCR7 in Rheumatoid Arthritis.2009

    • Author(s)
      Watanabe K, Nanki T, Kaneko K, Schall TJ, Miyasaka N
    • Organizer
      第9回国際炎症学会
    • Data Source
      KAKENHI-PROJECT-20591166
  • [Presentation] 多発性筋炎/皮膚筋炎におけるCX3CL1 (fractalkine) 発現の解析2009

    • Author(s)
      鈴木文仁、南木敏宏、今井俊夫、廣畑俊成、宮坂信之
    • Organizer
      第53回日本リウマチ学会総会
    • Data Source
      KAKENHI-PROJECT-20591166
  • [Presentation] The Effect of Synthetic Retinoid, Am80, On T Helper Cell Development and Antibody Production in Murine Collagen-Induced Arthritis.2009

    • Author(s)
      Nanki T, Sato A, Watanabe K, Kaneko K, Murakami Y, Ishido M, Miyasaka N
    • Organizer
      第73回アメリカリウマチ学会
    • Data Source
      KAKENHI-PROJECT-20591166
  • [Presentation] Chemerin and ChemR23 expression in rheumatoid arthritis: the therapeutic implication of the pathway.2009

    • Author(s)
      金子佳代子, 渡部香織, 宮坂信之, 南木敏宏
    • Organizer
      第3 回日本免疫学会総会
    • Data Source
      KAKENHI-PROJECT-20591166
  • [Presentation] Arthritic Joint-Targeting siRNA/Wrapsome? as a Treatment Strategy for Rheumatoid Arthritis.2009

    • Author(s)
      駒野有希子, 八木信宏, 尾上育美, 金子佳代子, 宮坂信之, 南木敏宏
    • Organizer
      第73回アメリカリウマチ学会
    • Data Source
      KAKENHI-PROJECT-20591166
  • [Presentation] siRNA/WrapsomeR を 用いた関節リウマチに対する新規治療法の開発2009

    • Author(s)
      駒野有希子、八木信宏、尾上育美、金子佳代子、宮坂信之、南木敏宏
    • Organizer
      第37回日本臨床免疫学会
    • Data Source
      KAKENHI-PROJECT-20591166
  • [Presentation] Study Group for Tacrolimus-induced Pulmonary Injury. Tacrolimus-Induced Pulmonary Injury in Patients with Rheumatoid Arthritis2009

    • Author(s)
      Koike R, Tanaka M, Komano Y, Sakai F, Sugiyama H, Nanki T, Miyasaka N, Harigai M
    • Organizer
      American College of Rheumatology 73^<rd> National Meetings
    • Place of Presentation
      Philadelphia, PA
    • Data Source
      KAKENHI-PROJECT-19590530
  • [Presentation] Analysis of serious adverse events in patients with Rheumatoid arthritis under the treatment with biologics ; a report from the Registry of Japanese Rheumatoid Arthritis Patients for Long-term Safety2009

    • Author(s)
      Komano Y, Nanki T, Tanaka M, Sakai R, Koike R, Miyasaka N, Harigai M
    • Organizer
      Annual European Congress of Rheumatology EULAR
    • Place of Presentation
      Copenhagen, Denmark
    • Data Source
      KAKENHI-PROJECT-19590530
  • [Presentation] The effect of synthetic retinoid, Am80, on T helper cell development and antibody production in murine collagen-induced arthritis.2009

    • Author(s)
      Sato A, Watanabe K, Kaneko K, Murakami Y, Miyasaka N, Nanki T
    • Organizer
      第39回日本免疫学会総会
    • Data Source
      KAKENHI-PROJECT-20591166
  • [Presentation] エタネルセプト投与下での関節リウマチ患者におけるニューモシスチス肺炎2009

    • Author(s)
      田中みち, 酒井良子, 駒野有希子, 南木敏宏, 小池竜司, 宮坂信之, 針谷正祥
    • Organizer
      第53回日本リウマチ学会総会・学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-19590530
  • [Presentation] siRNA/wrapped liposome複合体を用いた関節リウマチに対する新規治療法の開発2009

    • Author(s)
      駒野有希子、南木敏宏、八木信宏、尾上育美、金子佳代子、宮坂信之
    • Organizer
      第53回日本リウマチ学会総会
    • Data Source
      KAKENHI-PROJECT-20591166
  • [Presentation] Pneumocystis jiroveci pneumonia associated with etanercept in patients with rheumatoid arthritis2009

    • Author(s)
      Tanaka M, Sakai R, Koike R, Komano Y, Nanki T, Miyasaka N, Harigai M.
    • Organizer
      The 9th World Congress of Inflammation
    • Place of Presentation
      Tokyo
    • Data Source
      KAKENHI-PROJECT-19590530
  • [Presentation] リウマチ滑膜線維芽細胞におけるlet-7 microRNAの効果2008

    • Author(s)
      中里款, 宮坂信之, 上阪等
    • Organizer
      第36回日本臨床免疫学会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-19390272
  • [Presentation] 関節リウマチ治療の新たな標的分子2008

    • Author(s)
      上阪等, 村上洋介, 野々村美紀, 宮坂信之
    • Organizer
      第45回日本臨床分子医学会学術集会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-19390272
  • [Presentation] E3ユビキチンリガーゼc-MIRの抗炎症効果による関節炎治療2008

    • Author(s)
      豊本雅靖、石戸聡、宮坂信之、上阪等
    • Organizer
      第29回日本炎症・再生医学会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-19390272
  • [Presentation] Osteoclast Specific Dicer Deficiency Suppress Osteoclast Differentiation And Increase Bone Mass2008

    • Author(s)
      Mizoguchi F, Izu Y, Hayata T, Hemmi H, Nakashima K, Nakamura T, Kohsaka H,Miyasaka N, Harfe B, Kato S, Ezura Y, Noda M
    • Organizer
      2nd International Conference on Osteoimmunology
    • Place of Presentation
      Rhodes,Greece
    • Data Source
      KAKENHI-PROJECT-19390272
  • [Presentation] Pathogenic Role of CXCR7 in Rheumatoid Arthritis.2008

    • Author(s)
      Watanabe K, Nanki T, Penfold ME, Ohyanagi N, Kaneko K, Matsuda A, Matsumoto K, Miyasaka N
    • Organizer
      第72回アメリカリウマチ学会
    • Data Source
      KAKENHI-PROJECT-20591166
  • [Presentation] マウスのコラーゲン誘発性関節炎と破骨細胞に対するドパミン受容体阻害薬の効果2008

    • Author(s)
      中塩屋大樹、宮坂信之、松下祥、上阪等
    • Organizer
      第36回日本臨床免疫学会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-19390272
  • [Presentation] 関節リウマチの新しい標的分子Triggering receptorexpressed on myeloid cells-12008

    • Author(s)
      村上洋介、宮坂信之、上阪等
    • Organizer
      第36回日本臨床免疫学会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-19390272
  • [Presentation] 実験的多発性筋炎に対するレチノイド、Am80 の効果の検討2008

    • Author(s)
      南木敏宏、大柳菜歩、石堂美和子、窪田哲朗、宮坂信之
    • Organizer
      第52回日本リウマチ学会総会
    • Data Source
      KAKENHI-PROJECT-20591166
  • [Presentation] 関節炎治療の新たな標的分子Triggering receptor expressed on myeloid cells-1(TREM-1)2008

    • Author(s)
      村上洋介, 赤星透, 宮坂信之, 上阪等
    • Organizer
      第52回 日本リウマチ学会総会・学術集会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-19390272
  • [Presentation] 抗リン脂質抗体症候群の向血栓傾向におけるケモカインの作用に関する検討2008

    • Author(s)
      窪田哲朗、福谷泰子、南木敏宏、宮坂信之
    • Organizer
      第52回日本リウマチ学会総会
    • Data Source
      KAKENHI-PROJECT-20591166
  • [Presentation] Osteoclast Specific Dicer Deficiency Suppress Osteoclast Differentiation And Increase Bone Mass2008

    • Author(s)
      Mizoguchi F, Izu Y, Hayata T , Hemmi H, Nakashima K, Nakamura T, Kohsaka H, Miyasaka N, Harfe B, Kato S, Ezura Y, Noda M.
    • Organizer
      2nd International Conference on Osteoimmunology
    • Place of Presentation
      Greece
    • Data Source
      KAKENHI-PROJECT-19390272
  • [Presentation] Takao Koike A 2 Year-ExtendedFollow-Up Of The Phase I/Ii Trial Of Rituximab For Treatment Of Refractory Systemic Lupus Erythematosus2008

    • Author(s)
      Yoshiya Tanaka, Kazuhiko Yamamoto, Tsutomu Takeuchi, Nnorihiro Nishimoto, Nobuyuki Miyasaka, T Sumida, Tetsuji Sawada, Hitoshi Kohsaka, Isao Matsumoto, K. Saito
    • Organizer
      AnnualEuropean Congress of Rheumatology EULAR
    • Place of Presentation
      Paris France
    • Data Source
      KAKENHI-PROJECT-19390272
  • [Presentation] Pathogenic Role of CXCR7 in Rheumatoid Arthritis.2008

    • Author(s)
      Watanabe K, Nanki T, Penfold ME, Kaneko K, Matsuda A, Matsumoto K, Miyasaka N
    • Organizer
      第38回日本免疫学会総会
    • Data Source
      KAKENHI-PROJECT-20591166
  • [Presentation] リウマチ滑膜線維芽細胞におけるlet-7microRNAの効果2008

    • Author(s)
      中里款、宮坂信之、上阪等
    • Organizer
      第36回日本臨床免疫学会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-19390272
  • [Presentation] E3ユビクチンリガーゼc-MIRの抗炎症効果による関節炎治療2008

    • Author(s)
      豊本雅靖、石戸聡、宮坂信之、上阪等
    • Organizer
      第36回日本臨床免疫学会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-19390272
  • [Presentation] Preparation of a TAT-PTD CDKI FusionProtein that efficiently InhibitsProliferation and MMP-3 Production ofRheumatoid Synovial Fibroblasts2007

    • Author(s)
      Makoto Nakasato, Yoshinori Nonomura, Nobuyuki Miyasaka, Hitoshi Kohsaka
    • Organizer
      AmericanCollege of Rheumatology 71th National Meetings
    • Place of Presentation
      Boston, MA
    • Data Source
      KAKENHI-PROJECT-19390272
  • [Presentation] TAT-PTDを用いたリコンビナントCDKIタンパクの関節リウマチ滑膜線維芽細胞への導入2007

    • Author(s)
      中里款, 野々村美紀, 宮坂信之, 上阪等
    • Organizer
      第35回臨床免疫学会総会(ワークショップ)
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-19390272
  • [Presentation] 細胞膜透過型タンパク製剤を用いた新規抗リウマチ療法の研究(ワークショップ)2007

    • Author(s)
      中里款、野々村美紀、宮坂信之、上阪等
    • Organizer
      第28回日本炎症・再生医学会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-19390272
  • [Presentation] CDK4/6阻害薬による関節炎治療2007

    • Author(s)
      上阪 等、野々村美紀、村上洋介、関根知世子、宮坂信之
    • Organizer
      第51回日本リウマチ学会総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-19390272
  • [Presentation] CDK4/6阻害薬による関節炎治療2007

    • Author(s)
      上阪等、野々村美紀、村上洋介、関根知世子、宮坂信之
    • Organizer
      第51回日本リウマチ学会総会上阪
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-19390272
  • [Presentation] 膠原病における免疫抑制療法下の肺感染症に関する研究

    • Author(s)
      山崎隼人、酒井良子、小池竜司、田中みち、南木敏宏、渡部香織、宮坂信之、針谷正祥
    • Organizer
      リウマチヤングアカデミー
    • Place of Presentation
      北広島クラッセホテル
    • Data Source
      KAKENHI-PROJECT-23590171
  • [Presentation] 転写抑制因子ets variant 6の発現を抑制するmicroRNAの阻害は、 関節リウマチ滑膜線維芽細胞からの matrix metalloproteinase-3とinterleukin-6産生を抑制する

    • Author(s)
      長谷川久紀、溝口史高、宮坂信之、上阪等
    • Organizer
      第42回日本臨床免疫学会総会
    • Place of Presentation
      京王プラザホテル(東京都新宿)
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PROJECT-24591443
  • [Presentation] カンナビノイドによる関節炎抑制作用

    • Author(s)
      福田真、高安愛子、横山和佳、宮部千恵、宮部斉重、宮坂信之、南木敏宏
    • Organizer
      日本リウマチ学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23591435
  • 1.  KOHSAKA Hitoshi (00251554)
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    # of Collaborated Products: 54 results
  • 2.  HARIGAI Masayoshi (20238207)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 22 results
  • 3.  NANKI Toshihiro (00282749)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 50 results
  • 4.  KOIKE Ryuji (50250220)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 16 results
  • 5.  三浦 修 (10209710)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 6.  SAITO Kazuyoshi (30279327)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 7.  SAITO Ichiro (60147634)
    # of Collaborated Projects: 2 results
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  • 8.  ATSUMI Tatsuya (20301905)
    # of Collaborated Projects: 2 results
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  • 9.  MIZOGUCHI Fumitaka (60510360)
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  • 11.  山本 晃 (00281717)
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  • 12.  野々村 美紀 (30392070)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 10 results
  • 13.  SASANO Minoru
    # of Collaborated Projects: 2 results
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  • 14.  TAKENO Mitsuhiro (50236494)
    # of Collaborated Projects: 1 results
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  • 15.  KAMEDA Hideto (00265795)
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    # of Collaborated Products: 0 results
  • 16.  FUJII Takao (70255462)
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  • 17.  TSUTANI Kiichiro (80142040)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
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    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  TAMURA Naoto (20227284)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  TOHMA Shigeto (50207528)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  KAWAKAMI Atsushi (90325639)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  HAYASHI Taichi (00466674)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  NAKAMURA Takahiro (60415255)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  TANAKA Michi (50277141)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 25.  FUJITA Koichiro (90053107)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  TSUKIDATE Setsuko (40121256)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  AKAO Nobuaki (00126559)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  TERADA Yoshio (30251531)
    # of Collaborated Projects: 1 results
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    # of Collaborated Products: 0 results
  • 30.  林 良夫 (00127854)
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    # of Collaborated Products: 0 results
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    # of Collaborated Products: 0 results
  • 35.  佐々木 毅 (50110656)
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    # of Collaborated Products: 0 results
  • 36.  小池 隆夫 (80146795)
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    # of Collaborated Products: 0 results
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    # of Collaborated Products: 0 results
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    # of Collaborated Products: 0 results
  • 39.  杉本 八郎 (90362574)
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    # of Collaborated Products: 0 results
  • 40.  伊藤 聡 (00334681)
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    # of Collaborated Products: 0 results
  • 41.  村上 洋介 (30415319)
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    # of Collaborated Products: 0 results
  • 42.  山本 興太郎 (40000971)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 43.  青木 延雄 (20048937)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
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    # of Collaborated Products: 0 results
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    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 46.  TOTSUKA Tetsuya
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 47.  水島 昇
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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