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TAKARADA TAKESHI  宝田 剛志

… Alternative Names

Takarada Takeshi  宝田 剛志

TAKARADA Takeshi  宝田 剛志

寳田 剛志  タカラダ タケシ

宝田 剛志  タカラダ タケシ

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Researcher Number 30377428
Other IDs
  • ORCIDhttps://orcid.org/0000-0002-2363-7704
External Links
Affiliation (Current) 2025: 岡山大学, 医歯薬学域, 教授
Affiliation (based on the past Project Information) *help 2021 – 2025: 岡山大学, 医歯薬学域, 教授
2020 – 2021: 岡山大学, 医歯薬学総合研究科, 教授
2018 – 2019: 岡山大学, 医歯薬学総合研究科, 研究教授
2016 – 2017: 岡山大学, 医歯薬学総合研究科, 准教授
2014 – 2015: 金沢大学, 薬学系, 助教 … More
2008 – 2012: Kanazawa University, 薬学系, 助教
2007: 金沢大学, 自然科学研究所, 助教
2005 – 2006: 金沢大学, 自然科学研究科, 教務職員 Less
Review Section/Research Field
Principal Investigator
Medium-sized Section 90:Biomedical engineering and related fields / Basic Section 47060:Clinical pharmacy-related / Biological Sciences / Pathological medical chemistry / Medium-sized Section 42:Veterinary medical science, animal science, and related fields / Dental engineering/Regenerative dentistry / Complex Systems Disease Theory / Neurochemistry/Neuropharmacology / Biological pharmacy
Except Principal Investigator
Basic Section 56020:Orthopedics-related … More / Basic Section 50020:Tumor diagnostics and therapeutics-related / Basic Section 57070:Developmental dentistry-related / Basic Section 56070:Plastic and reconstructive surgery-related / Basic Section 57050:Prosthodontics-related / Medium-sized Section 57:Oral science and related fields / Prosthodontics/ Dental materials science and / Basic Section 58020:Hygiene and public health-related: including laboratory approach / Medium-sized Section 50:Oncology and related fields / Basic Section 59040:Nutrition science and health science-related / Basic Section 57030:Conservative dentistry-related / Basic Section 48010:Anatomy-related / Pathological medical chemistry / Biological Sciences Less
Keywords
Principal Investigator
ヒト多能性幹細胞 / グリア / 光操作 / 体内時計 / ペリサイト / 間葉系幹細胞 / 血液脳関門 / Runx2 / アストロサイト / 軟骨細胞 … More / 時計遺伝子 / 発生・分化 / 細胞・組織 / iPS / 創薬スクリーニング / 軟骨 / iPS細胞 / 光遺伝学 / 幹細胞 / 光操作技術 / 遺伝子改変マウス / 発現制御 / 脳神経疾患 / イメージング / PETイメージングプローブ / PET/SPECT / 神経科学 / 転写制御因子 / Neurovascular Unit / グルタミン酸トランスポーター / 小胞体ストレス / グルタミン酸 / runx2 / コンディショナル欠損マウス / 神経細胞 / Per1 / Bmal1 / Bmall / Indian hedgehog / indian hedgehog / 骨関節組織 / 生理活性 / シグナル伝達 / 薬理学 … More
Except Principal Investigator
肢芽間葉系細胞 / PRRX1 / 骨肉腫 / iPS干渉 / 骨再生 / 骨芽細胞 / 骨芽細胞分化 / 軟骨再生 / 変形性関節症 / 軟骨 / 肉腫 / ユーイング肉腫 / ヒト多能性幹細胞 / 再生 / 歯周病 / 増殖 / 肺転移 / 悪性骨・軟部腫瘍 / iPS干渉法 / 転写因子 / 老化 / 幹細胞 / 間葉系幹細胞 / BMP-2 / 糖代謝 / 破骨細胞 / 骨組織 / スキャフォールドフリー / 細胞外マトリックス / 脱細胞化 / 細胞自己凝集 / グルタールアルデヒド / iPS細胞 / 培養軟骨 / 創薬スクリーニング / ゲノム編集 / 多能性幹細胞 / ExpLBM / hiPSC / 感受性遺伝子SNP / OA / ヒト多能性幹細胞(iPS細胞) / ハイブリッドマテリアル / 変形性股関節症 / iPS cells / scaffold / 3D bioprinting / RNA編集 / CRISPR/dCas13 / サルコペニア / lncRNA / 無糖培地処理 / 骨化関連遺伝子解析 / 培養軟骨組織体 / 内軟骨性骨化 / 骨化抑制 / 足関節 / 骨軟骨再生 / 神経線維腫症1型 / ミトコンドリア / 腫瘍免疫 / 口蓋裂 / Fillamin A / 口蓋発生 / Filamin A / 発がん / 滑膜肉腫 / 軟骨肉腫 / 自然発症モデル / AYA世代 / がん幹細胞 / 病態モデリング / 希少がん / spatial RNA-seq / 歯胚 / トランスクリプトーム / バイオインフォマティクス / scRNA-seq / 歯 / ゲノム医科学 / 生体分子医学 / 肉腫モデル / MPNST / 肺 / 全身性疾患 / 細胞障害性 / 遠隔臓器 / Outer membrane vesicles / 歯周病原菌 / 糖尿病 / 肝臓 / 細胞外分泌小胞 / 骨形成・抑制メカニズム / 口腔インプラント / 骨髄 / 1細胞解析 / 骨吸収 / 骨形成 / MDA5 / Singleton-Merten / I型インターフェロン / マクロファージ / HMGB1 / 創傷治癒 / 低栄養 / 炎症 / 複合がん免疫療法 / 悪性軟部腫瘍 / シグナル伝達 / 増殖抑制 / PRX1 / 浸潤 / 転移 / 糖鎖 / 未分化間葉系細胞 / 機械的刺激 / エクソソーム / 間葉系細胞 / メカニカルストレス / エナメル芽細胞マスター転写因子 / 象牙芽細胞マスター転写因子 / 器官原基法 / エナメル芽細胞マスター遺伝子 / 象牙芽細胞マスター遺伝子 / エナメル芽細胞 / 象牙芽細胞 / 歯の再生 / ステムセルエイジング / 顔面半側肥大症 / 顔面半側萎縮症 / sonic hedgehog / 顎顔面形成 / 神経 / 顎顔面形態形成 / 顔面神経 / 三叉神経 / トリプトファン / 感染 / 骨膜 / 人工骨膜 / 難治性骨欠損 / 難治性疾患 / 脂質代謝 / 内分泌 / 分泌因子 / 骨粗鬆症 / 骨代謝 / ホルモン / growth differentiation factor 15 / 骨細胞 / Osterix / Sox9 / ミクログリア細胞 / 神経細胞 / 制御遺伝子 / 骨関節系細胞 / RT-PCR / mRNA発現 / 発現ベクター / 転写制御因子 / Runx2 / C6グリオーマ細胞 / アストログリア細胞 Less
  • Research Projects

    (43 results)
  • Research Products

    (241 results)
  • Co-Researchers

    (79 People)
  •  ヒト肉腫オルガノイドを利用した薬剤スクリーニング技術の開発Principal Investigator

    • Principal Investigator
      宝田 剛志
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 47060:Clinical pharmacy-related
    • Research Institution
      Okayama University
  •  難病における病的バリアントに特有な疾患進行メカニズムの解明

    • Principal Investigator
      濱田 全紀
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Okayama University
  •  ヒトiPS細胞とバイオマテリアルを用いたChondro-pasteの開発

    • Principal Investigator
      井上 智博
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      Okayama University
  •  巨大骨欠損に対する新規治療の開発

    • Principal Investigator
      横山 裕介
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      Okayama University
  •  軟骨再生による変形性足関節症に対する新規治療の開発

    • Principal Investigator
      雑賀 建多
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      Okayama University
  •  培養軟骨組織体における内軟骨性骨化抑制へのアプローチとメカニズムの解明

    • Principal Investigator
      北口 陽平
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56070:Plastic and reconstructive surgery-related
    • Research Institution
      Okayama University
  •  ヒトiPS細胞技術を利用したヒト肉腫オルガノイドパネルの開発Principal Investigator

    • Principal Investigator
      宝田 剛志
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 90:Biomedical engineering and related fields
    • Research Institution
      Okayama University
  •  ヒト骨格アセンブロイドを利用した骨格形成過程の4DバイオイメージングPrincipal Investigator

    • Principal Investigator
      宝田 剛志
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Fund for the Promotion of Joint International Research (International Collaborative Research)
    • Review Section
      Medium-sized Section 90:Biomedical engineering and related fields
    • Research Institution
      Okayama University
  •  The lncRNA landscape of skeletal muscle cell biotransformation with aging.

    • Principal Investigator
      伊藤 達男
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 58020:Hygiene and public health-related: including laboratory approach
    • Research Institution
      Kawasaki Medical School
  •  Development of new treatment for cartilage regeneration for hip osteoarthritis

    • Principal Investigator
      山田 和希
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      Okayama University
  •  ヒトiPS細胞由来肢芽間葉系細胞による変形性関節症の遺伝・環境複合素因に関する研究

    • Principal Investigator
      高尾 知佳
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      Okayama University
  •  Development of human-derived extracellular matrix product using scaffold-free tissue-engineered cartilage

    • Principal Investigator
      太田 智之
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56070:Plastic and reconstructive surgery-related
    • Research Institution
      Okayama University
  •  関節軟骨の光in vivoイメージング技術の開発

    • Principal Investigator
      鉄永 智紀
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      Okayama University
  •  新規肉腫モデルを用いた肉腫発生メカニズムの解明と治療標的分子同定の試み

    • Principal Investigator
      上原 健敬
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      Okayama University
  •  Development of new molecular targeted therapy for osteosarcoma lung metastasis

    • Principal Investigator
      中田 英二
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      Okayama University
  •  Filamin A mediated epithelial-mesenchymal transition during embryonic palate development

    • Principal Investigator
      早野 暁
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57070:Developmental dentistry-related
    • Research Institution
      Okayama University
  •  Spatiotemporal T-cell differentiation dynamics in the tumor "peripheral" environment

    • Principal Investigator
      Togashi Yosuke
    • Project Period (FY)
      2022 – 2023
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 50:Oncology and related fields
    • Research Institution
      Okayama University
  •  悪性軟部腫瘍におけるPRRX1の機能解析とその新規薬物療法への応用

    • Principal Investigator
      たき平 将太
    • Project Period (FY)
      2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Okayama University
  •  Development of tooth regenerative technology based on the spatiotemporal transcriptome analysis and iPS interference

    • Principal Investigator
      窪木 拓男
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 57:Oral science and related fields
    • Research Institution
      Okayama University
  •  Study on novel biomarkers using human pluripotent stem cell derived sarcoma model

    • Principal Investigator
      Yamada Dasiuke
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Okayama University
  •  ヒト関節軟骨オルガノイドを利用した革新的創薬スクリーニング技術の開発Principal Investigator

    • Principal Investigator
      宝田 剛志
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 47060:Clinical pharmacy-related
    • Research Institution
      Okayama University
  •  in vivo genome engineering by tTA-dependent photoactivatable Cre recombinase knock-in mousePrincipal Investigator

    • Principal Investigator
      TAKARADA TAKESHI
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 42:Veterinary medical science, animal science, and related fields
    • Research Institution
      Okayama University
  •  Regulation of bone regeneration by exosomes and sugar chains derived from mechanical stress highly reactive mesenchymal stem cells

    • Principal Investigator
      Ikegame Mika
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 48010:Anatomy-related
    • Research Institution
      Okayama University
  •  Development of new combined cancer immunotherapy for malignant soft tissue tumor

    • Principal Investigator
      Nakata Eiji
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      Okayama University
  •  Malnutrition delayed wound healing by HMGB1-related prolonged inflammation

    • Principal Investigator
      Yamashiro Keisuke
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57030:Conservative dentistry-related
    • Research Institution
      Kobe Tokiwa Junior College
      Okayama University
  •  Role of Type I Interferon in craniofacial morphogenesis

    • Principal Investigator
      Hayano Satoru
    • Project Period (FY)
      2019 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57070:Developmental dentistry-related
    • Research Institution
      Okayama University
  •  The clarification of bone formation and absorption mechanism in the bone marrow microenvironment

    • Principal Investigator
      Ono Mitsuaki
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 57050:Prosthodontics-related
    • Research Institution
      Okayama University
  •  The role of extracellular vesicles of oral bacteria in systemic disease

    • Principal Investigator
      Okamura Hirohiko
    • Project Period (FY)
      2019 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 59040:Nutrition science and health science-related
    • Research Institution
      Okayama University
  •  Considering the effects of nerves on maxillofacial formation-elucidation of the etiology of hemifacial atrophy and hemifacial hypertrophy-

    • Principal Investigator
      Kawanabe Noriaki
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57070:Developmental dentistry-related
    • Research Institution
      Okayama University
  •  Elucidation of undifferentiated maintaining mechanism of stem cell towards the control of stem cell aging

    • Principal Investigator
      Kuboki Takuo
    • Project Period (FY)
      2018 – 2019
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 57:Oral science and related fields
    • Research Institution
      Okayama University
  •  Understanding of molecular mechanisms of tooth development using iPS interference and application to tooth regeneration techniques

    • Principal Investigator
      Kuboki Takuo
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 57050:Prosthodontics-related
    • Research Institution
      Okayama University
  •  Application of artificial periosteum containing BMP-2 to the treatment of refractory bone disease and bone nonunion.

    • Principal Investigator
      Kimura-Ono Aya
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Prosthodontics/ Dental materials science and
    • Research Institution
      Okayama University
  •  Molecular understanding of the accumulation of mesenchymal stem cells in vivo by photo-manipulation techniques and its application to bone-related diseasesPrincipal Investigator

    • Principal Investigator
      Takarada Takeshi
    • Project Period (FY)
      2017 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Dental engineering/Regenerative dentistry
    • Research Institution
      Okayama University
  •  必須アミノ酸トリプトファンによる幹細胞老化制御機構の解明・骨質改善治療への応用

    • Principal Investigator
      笈田 育尚
    • Project Period (FY)
      2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Prosthodontics/ Dental materials science and
    • Research Institution
      Okayama University
  •  体内時計制御グリアネットワークによる「精神-疼痛」連関メカニズムの解明Principal Investigator

    • Principal Investigator
      宝田 剛志
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Okayama University
  •  Pericyte imaging for the early detection of psychiatric diseasesPrincipal Investigator

    • Principal Investigator
      Takarada Takeshi
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Complex Systems Disease Theory
    • Research Institution
      Okayama University
  •  体内時計によるグリアネットワーク調節に注目した「精神-疼痛」連関メカニズムの解明Principal Investigator

    • Principal Investigator
      宝田 剛志
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Kanazawa University
  •  in vivo analysis of Mesenchymal stem cells using Runx2 conditional KO mousePrincipal Investigator

    • Principal Investigator
      Takarada Takeshi
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Okayama University
      Kanazawa University
  •  Regulatory mechanisms of central nervous system by Runx2Principal Investigator

    • Principal Investigator
      TAKARADA Takeshi
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      Kanazawa University
  •  Bone as an endocrine organ

    • Principal Investigator
      HINOI Eiichi
    • Project Period (FY)
      2010 – 2011
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Kanazawa University
  •  Joint disease and clock genesPrincipal Investigator

    • Principal Investigator
      TAKARADA Takeshi
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Kanazawa University
  •  新規シグナル分子によるグリアニューロン相互回路網構築の可能性探究

    • Principal Investigator
      米田 幸雄
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kanazawa University
  •  細胞間コミュニケーションにおけるセリン光学異性体に関する研究Principal Investigator

    • Principal Investigator
      宝田 剛志
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      Kanazawa University

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All Journal Article Presentation Book Patent

  • [Book] 臨床精神薬理ハンドブック(監修;樋口輝彦、小山司)2009

    • Author(s)
      米田幸雄, 宝田剛志
    • Total Pages
      6
    • Publisher
      医学書院
    • Data Source
      KAKENHI-PROJECT-20790250
  • [Journal Article] iPSC 由来ヒト軟骨前駆細胞を使用した 形状型軟骨組織体の開発2024

    • Author(s)
      太田智之、岩井良輔、木股敬裕、宝田剛志
    • Journal Title

      BIOINDUSTRY

      Volume: 2 Pages: 31-36

    • Data Source
      KAKENHI-PROJECT-23K09099
  • [Journal Article] PRRX1-TOP2A interaction is a malignancy-promoting factor in human malignant peripheral nerve sheath tumours2024

    • Author(s)
      Takihira Shota、Yamada Daisuke、Osone Tatsunori、Takao Tomoka、Sakaguchi Masakiyo、Hakozaki Michiyuki、Itano Takuto、Nakata Eiji、Fujiwara Tomohiro、Kunisada Toshiyuki、Ozaki Toshifumi、Takarada Takeshi
    • Journal Title

      British Journal of Cancer

      Volume: In press Issue: 9 Pages: 1493-1504

    • DOI

      10.1038/s41416-024-02632-8

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K18329, KAKENHI-PROJECT-21K07192, KAKENHI-PROJECT-22H04923, KAKENHI-PROJECT-23K24461, KAKENHI-PROJECT-23K27439
  • [Journal Article] Fabrication of shape-designable cartilage from human induced pluripotent stem cell-derived chondroprogenitors using a cell self-aggregation technique2023

    • Author(s)
      Tomoyuki Ota, Tomoka Takao, Ryosuke Iwai, Takeshi Moriwaki, Yohei Kitaguchi, Yuki Fujisawa, Daisuke Yamada, Yoshihiro Kimata and Takeshi Takarada
    • Journal Title

      Biomedical Materials

      Volume: 18 Issue: 6 Pages: 1-14

    • DOI

      10.1088/1748-605x/ad02d1

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23K09099, KAKENHI-PROJECT-21K09766, KAKENHI-PROJECT-23K21368
  • [Journal Article] Development of cartilage tissue using a stirred bioreactor and human iPSC-derived limb bud mesenchymal cells2023

    • Author(s)
      Fujisawa Yuki、Takao Tomoka、Yamada Daisuke、Takarada Takeshi
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 687 Pages: 149146-149146

    • DOI

      10.1016/j.bbrc.2023.149146

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K21368
  • [Journal Article] A novel chondrocyte sheet fabrication using human-induced pluripotent stem cell-derived expandable limb-bud mesenchymal cells2023

    • Author(s)
      Takao Tomoka、Sato Masato、Fujisawa Yuki、Toyoda Eriko、Yamada Daisuke、Hitsumoto Yukio、Nakata Eiji、Ozaki Toshifumi、Takarada Takeshi
    • Journal Title

      Stem Cell Research & Therapy

      Volume: 14 Issue: 1 Pages: 34-34

    • DOI

      10.1186/s13287-023-03252-4

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K09356, KAKENHI-PROJECT-23K21368, KAKENHI-PROJECT-20K07297
  • [Journal Article] Identification of Surface Antigens That Define Human Pluripotent Stem Cell-Derived PRRX1+Limb-Bud-like Mesenchymal Cells2022

    • Author(s)
      Yamada Daisuke、Takao Tomoka、Nakamura Masahiro、Kitano Toki、Nakata Eiji、Takarada Takeshi
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 23 Issue: 5 Pages: 2661-2661

    • DOI

      10.3390/ijms23052661

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23K21368
  • [Journal Article] Fabrication of scaffold-free mesenchyme tissue bands by cell self-aggregation technique for potential use in tissue regeneration2022

    • Author(s)
      Ota Tomoyuki、Iwai Ryosuke、Kitaguchi Yohei、Takarada Takeshi、Kimata Yoshihiro
    • Journal Title

      Biomedical Materials

      Volume: 17 Issue: 6 Pages: 065021-065021

    • DOI

      10.1088/1748-605x/ac9c7f

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K09766, KAKENHI-PROJECT-18K12088, KAKENHI-PROJECT-23K21368
  • [Journal Article] Establishment of a human pluripotent stem cell-derived MKX-td Tomato reporter system2022

    • Author(s)
      Fujisawa Yuki、Ming Lu、Yamada Daisuke、Takao Tomoka、Takarada Takeshi
    • Journal Title

      Stem Cell Research & Therapy

      Volume: 13 Issue: 1

    • DOI

      10.1186/s13287-022-03203-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23K21368
  • [Journal Article] Mouse Model for Optogenetic Genome Engineering.2022

    • Author(s)
      Takao T, Yamada D, Takarada T.
    • Journal Title

      Acta Med Okayama.

      Volume: 76 Pages: 1-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K21373
  • [Journal Article] A protocol to induce expandable limb-bud mesenchymal cells from human pluripotent stem cells2022

    • Author(s)
      Takao Tomoka、Yamada Daisuke、Takarada Takeshi
    • Journal Title

      STAR Protocols

      Volume: 3 Issue: 4 Pages: 101786-101786

    • DOI

      10.1016/j.xpro.2022.101786

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23K21368
  • [Journal Article] O‐GlcNAcylation drives calcium signaling toward osteoblast differentiation: A bioinformatics‐oriented study2021

    • Author(s)
      Weng Yao、Wang Ziyi、Fukuhara Yoko、Tanai Airi、Ikegame Mika、Yamada Daisuke、Takarada Takeshi、Izawa Takashi、Hayano Satoru、Yoshida Kaya、Kamioka Hiroshi、Okamura Hirohiko
    • Journal Title

      BioFactors

      Volume: 47 Issue: 6 Pages: 992-1015

    • DOI

      10.1002/biof.1774

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H03011, KAKENHI-PROJECT-19H03859, KAKENHI-PROJECT-19H04051, KAKENHI-PROJECT-21K19644, KAKENHI-PROJECT-21K17211, KAKENHI-PROJECT-18KK0464, KAKENHI-PROJECT-23K21368
  • [Journal Article] PRRX1 promotes malignant properties in human osteosarcoma2021

    • Author(s)
      Joko Ryoji、Yamada Daisuke、Nakamura Masahiro、Yoshida Aki、Takihira Shota、Takao Tomoka、Lu Ming、Sato Kohei、Ito Tatsuo、Kunisada Toshiyuki、Nakata Eiji、Ozaki Toshifumi、Takarada Takeshi
    • Journal Title

      Translational Oncology

      Volume: 14 Issue: 1 Pages: 100960-100960

    • DOI

      10.1016/j.tranon.2020.100960

    • NAID

      120007004820

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K21373, KAKENHI-PROJECT-19K18705, KAKENHI-PROJECT-17H04399, KAKENHI-PROJECT-18K15212, KAKENHI-PROJECT-19K09551, KAKENHI-PROJECT-21K07192
  • [Journal Article] RUNX2 regulates leukemic cell metabolism and chemotaxis in high-risk T cell acute lymphoblastic leukemia2021

    • Author(s)
      Matthijssens Filip、Sharma Nitesh D.、Takarada Takeshi、et al.
    • Journal Title

      Journal of Clinical Investigation

      Volume: 131 Issue: 6

    • DOI

      10.1172/jci141566

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K21373, KAKENHI-PROJECT-17H04399
  • [Journal Article] Induction and expansion of human PRRX1+ limb-bud-like mesenchymal cells from pluripotent stem cells2021

    • Author(s)
      Yamada Daisuke、Nakamura Masahiro、Takao Tomoka、Takihira Shota、Yoshida Aki、Kawai Shunsuke、Miura Akihiro、Ming Lu、Yoshitomi Hiroyuki、Gozu Mai、Okamoto Kumi、Hojo Hironori、Kusaka Naoyuki、Iwai Ryosuke、Nakata Eiji、Ozaki Toshifumi、Toguchida Junya、Takarada Takeshi
    • Journal Title

      Nature Biomedical Engineering

      Volume: 5 Issue: 8 Pages: 926-940

    • DOI

      10.1038/s41551-021-00778-x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21H04952, KAKENHI-PROJECT-20H03885, KAKENHI-PROJECT-21K07192, KAKENHI-PROJECT-21K19589, KAKENHI-PROJECT-21K19883, KAKENHI-PROJECT-23K21368, KAKENHI-PROJECT-22K09401
  • [Journal Article] Oncogenic potential of human pluripotent stem cell‐derived lung organoids with <scp>HER2</scp> overexpression2021

    • Author(s)
      Miura Akihiro、Yamada Daisuke、Nakamura Masahiro、Tomida Shuta、Shimizu Dai、Jiang Yan、Takao Tomoka、Yamamoto Hiromasa、Suzawa Ken、Shien Kazuhiko、Yamane Masaomi、Sakaguchi Masakiyo、Toyooka Shinichi、Takarada Takeshi
    • Journal Title

      International Journal of Cancer

      Volume: 149 Issue: 8 Pages: 1593-1604

    • DOI

      10.1002/ijc.33713

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H03516, KAKENHI-PROJECT-20H03771, KAKENHI-PROJECT-21K07192, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-23K21368
  • [Journal Article] Core Binding Factors are essential for ovulation, luteinization, and female fertility in mice2020

    • Author(s)
      Lee-Thacker Somang、Jeon Hayce、Choi Yohan、Taniuchi Ichiro、Takarada Takeshi、Yoneda Yukio、Ko CheMyong、Jo Misung
    • Journal Title

      Scientific Reports

      Volume: 10 Issue: 1 Pages: 9921-9921

    • DOI

      10.1038/s41598-020-64257-0

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-19H05747, KAKENHI-PROJECT-17H04399
  • [Journal Article] BMP-2/β-TCP Local Delivery for Bone Regeneration in MRONJ-Like Mouse Model2020

    • Author(s)
      Mikai Akihiro、Ono Mitsuaki、Tosa Ikue、Nguyen Ha Thi Thu、Hara Emilio Satoshi、Nosho Shuji、Kimura-Ono Aya、Nawachi Kumiko、Takarada Takeshi、Kuboki Takuo、Oohashi Toshitaka
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 21 Issue: 19 Pages: 7028-7028

    • DOI

      10.3390/ijms21197028

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K10246, KAKENHI-PROJECT-20K21679, KAKENHI-PROJECT-20K23108, KAKENHI-PROJECT-17H04399, KAKENHI-PROJECT-18H02991, KAKENHI-PROJECT-19H03842, KAKENHI-PROJECT-19K24146
  • [Journal Article] A RUNX2 stabilization pathway mediates physiologic and pathologic bone formation2020

    • Author(s)
      Kim Jung-Min、Yang Yeon-Suk、Park Kwang Hwan、Ge Xianpeng、Xu Ren、Li Na、Song Minkyung、Chun Hyunho、Bok Seoyeon、Charles Julia F.、Filhol-Cochet Odile、Boldyreff Brigitte、Dinter Teresa、Yu Paul B.、Kon Ning、Gu Wei、Takarada Takeshi、Greenblatt Matthew B.、Shim Jae-Hyuck
    • Journal Title

      Nature Communications

      Volume: 11 Issue: 1 Pages: 2289-2289

    • DOI

      10.1038/s41467-020-16038-6

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04399
  • [Journal Article] Establishment of a tTA-dependent photoactiveatable Cre recombinease knock-in mouse model for optogenetic genome engineering.2020

    • Author(s)
      9.Takao, T., Hiraoka, Y., Kawabe, K., Yamada, D., Ming, L., Tanaka, K., Sato, M., Takarada, T.
    • Journal Title

      Biochem. Biophys. Res. Commun.

      Volume: 526 Issue: 1 Pages: 213-217

    • DOI

      10.1016/j.bbrc.2020.03.015

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19494, KAKENHI-PROJECT-19K18705, KAKENHI-PROJECT-17H02216, KAKENHI-PROJECT-17H04399
  • [Journal Article] Glutamatergic neurons in the medial prefrontal cortex mediate the formation and retrieval of cocaine-associated memories in mice2019

    • Author(s)
      Zhang Tong、Yanagida Junko、Kamii Hironori、Wada Shintaro、Domoto Masaki、Sasase Hitoki、Deyama Satoshi、Takarada Takeshi、Hinoi Eiichi、Sakimura Kenji、Yamanaka Akihiro、Maejima Takashi、Mieda Michihiro、Sakurai Takeshi、Nishitani Naoya、Nagayasu Kazuki、Kaneko Shuji、Minami Masabumi、Kaneda Katsuyuki
    • Journal Title

      Addiction Biology

      Volume: 印刷中 Issue: 1 Pages: 1-11

    • DOI

      10.1111/adb.12723

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K06520, KAKENHI-PROJECT-18K19421, KAKENHI-PROJECT-18KK0223, KAKENHI-PUBLICLY-17H05563, KAKENHI-PUBLICLY-18H04941, KAKENHI-PUBLICLY-18H04972, KAKENHI-PUBLICLY-18H05124, KAKENHI-PROJECT-16H05120, KAKENHI-PROJECT-18H02523, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-18K06519, KAKENHI-PLANNED-16H06401, KAKENHI-PUBLICLY-19H05013, KAKENHI-PROJECT-17H04399, KAKENHI-PROJECT-18H02595, KAKENHI-PROJECT-18K14919, KAKENHI-ORGANIZER-16H06400, KAKENHI-PUBLICLY-19H05016
  • [Journal Article] Postnatal Runx2 deletion leads to low bone mass and adipocyte accumulation in mice bone tissues2019

    • Author(s)
      Tosa Ikue、Yamada Daisuke、Yasumatsu Misa、Hinoi Eiichi、Ono Mitsuaki、Oohashi Toshitaka、Kuboki Takuo、Takarada Takeshi
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 516 Issue: 4 Pages: 1229-1233

    • DOI

      10.1016/j.bbrc.2019.07.014

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H04399
  • [Journal Article] Inhibition of the glutamine transporter SNAT1 confers neuroprotection in mice by modulating the mTOR-autophagy system2019

    • Author(s)
      Yamada Daisuke、Kawabe Kenji、Tosa Ikue、Tsukamoto Shunpei、Nakazato Ryota、Kou Miki、Fujikawa Koichi、Nakamura Saki、Ono Mitsuaki、Oohashi Toshitaka、Kaneko Mari、Go Shioi、Hinoi Eiichi、Yoneda Yukio、Takarada Takeshi
    • Journal Title

      Communications Biology

      Volume: 2 Issue: 1

    • DOI

      10.1038/s42003-019-0582-4

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H04399
  • [Journal Article] Bone Marrow Cells Inhibit BMP-2-Induced Osteoblast Activity in the Marrow Environment2018

    • Author(s)
      Nguyen Ha Thi、Ono Mitsuaki、Oida Yasutaka、Hara Emilio Satoshi、Komori Taishi、Akiyama Kentaro、Nguyen Ha Thi Thu、Aung Kyaw Thu、Pham Hai Thanh、Tosa Ikue、Takarada Takeshi、Matsuo Koichi、Mizoguchi Toshihide、Oohashi Toshitaka、Kuboki Takuo
    • Journal Title

      Journal of Bone and Mineral Research

      Volume: 34 Issue: 2 Pages: 327-332

    • DOI

      10.1002/jbmr.3598

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K11750, KAKENHI-PROJECT-16H05524, KAKENHI-PROJECT-18H02991, KAKENHI-PROJECT-16K11624, KAKENHI-PROJECT-17H04374, KAKENHI-PROJECT-16KK0190, KAKENHI-PROJECT-19K22727
  • [Journal Article] Type IV collagen α6 chain is a regulator of keratin 10 in keratinization of oral mucosal epithelium.2018

    • Author(s)
      Komori T, Ono M, Hara ES, Ueda J, Nguyen HTT, Nguyen HT, Yonezawa T, Maeba T, Ono A, Takarada T, Momota R, Maekawa K, Kuboki T, Oohashi T
    • Journal Title

      Scientific Reports

      Volume: 8(1) Pages: 2612-2612

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K19646
  • [Journal Article] Core Binding Factor β Expression in Ovarian Granulosa Cells Is Essential for Female Fertility.2018

    • Author(s)
      Lee-Thacker S, Choi Y, Taniuchi I, Takarada T, Yoneda Y, Ko C, Jo M.
    • Journal Title

      Endocrinology.

      Volume: 159 Issue: 5 Pages: 2094-2109

    • DOI

      10.1210/en.2018-00011

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04399
  • [Journal Article] Radiobrominated benzimidazole-quinoline derivatives as Platelet-derived growth factor receptor beta (PDGFRβ) imaging probes.2018

    • Author(s)
      Effendi N, Mishiro K, Takarada T, Makino A, Yamada D, Kitamura Y, Shiba K, Kiyono Y, Odani A, Ogawa K.
    • Journal Title

      Sci Rep.

      Volume: 8 Issue: 1 Pages: 10369-10369

    • DOI

      10.1038/s41598-018-28529-0

    • NAID

      120007185660

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H04399, KAKENHI-PROJECT-16KT0192
  • [Journal Article] The MAPK Erk5 is necessary for proper skeletogenesis involving a Smurf-Smad-Sox9 molecular axis.2018

    • Author(s)
      Iezaki T, Fukasawa K, Horie T, Park G, Robinson S, Nakaya M, Fujita H, Onishi Y, Ozaki K, Kanayama T, Hiraiwa M, Kitaguchi Y, Kaneda K, Yoneda Y, Takarada T, Guo XE, Kurose H, Hinoi E.
    • Journal Title

      Development

      Volume: 145 Issue: 14 Pages: 164004-164004

    • DOI

      10.1242/dev.164004

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17KT0051, KAKENHI-PROJECT-18K19404, KAKENHI-PUBLICLY-17H05510, KAKENHI-PUBLICLY-18H04971, KAKENHI-PROJECT-16H05131, KAKENHI-PROJECT-17H03984, KAKENHI-PROJECT-17H04399, KAKENHI-PROJECT-18J13309, KAKENHI-PROJECT-18J13310, KAKENHI-PROJECT-18K14916, KAKENHI-ORGANIZER-15H05935
  • [Journal Article] Type IV collagen α6 chain is a regulator of keratin 10 in keratinization of oral mucosal epithelium2018

    • Author(s)
      Komori T, Ono M, Hara ES, Ueda J, Nguyen HTT, Nguyen HT, Yonezawa T, Maeba T, Ono A, Takarada T, Momota R, Maekawa K, Kuboki T, Oohashi T
    • Journal Title

      Scientific Reports

      Volume: 8 Issue: 1 Pages: 2612-2612

    • DOI

      10.1038/s41598-018-21000-0

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26253088, KAKENHI-PROJECT-16H05524, KAKENHI-PROJECT-26462243, KAKENHI-PROJECT-16K15802, KAKENHI-PROJECT-15H05026, KAKENHI-PROJECT-17H04399
  • [Journal Article] Deletion of Runx2 in Articular Chondrocytes Decelerates the Progression of DMM-Induced Osteoarthritis in Adult Mice2017

    • Author(s)
      Liao Lifan、Zhang Shanxing、Gu Jianhong、Takarada Takeshi、Yoneda Yukio、Huang Jian、Zhao Lan、Oh Chun-do、Li Jun、Wang Baoli、Wang Meiqing、Chen Di
    • Journal Title

      Scientific Reports

      Volume: 7 Issue: 1 Pages: 2371-2371

    • DOI

      10.1038/s41598-017-02490-w

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H04399
  • [Journal Article] Synthesis and evaluation of radioiodinated 1-{2-[5-(2-methoxyethoxy)-1 H -benzo[ d ]imidazol-1-yl]quinolin-8-yl}piperidin-4-amine derivatives for platelet-derived growth factor receptor β (PDGFRβ) imaging2017

    • Author(s)
      Effendi Nurmaya、Ogawa Kazuma、Mishiro Kenji、Takarada Takeshi、Yamada Daisuke、Kitamura Yoji、Shiba Kazuhiro、Maeda Takehiko、Odani Akira
    • Journal Title

      Bioorganic & Medicinal Chemistry

      Volume: 25 Issue: 20 Pages: 5576-5585

    • DOI

      10.1016/j.bmc.2017.08.025

    • NAID

      120006375101

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16KT0192, KAKENHI-PUBLICLY-16H01332, KAKENHI-PROJECT-15K08682, KAKENHI-PROJECT-15K09886
  • [Journal Article] Physiological role of urothelial cancer-associated one long noncoding RNA in human skeletogenic cell differentiation2017

    • Author(s)
      Ishikawa T, Nishida T, Ono M, Takarada T, Nguyen HT, Kurihara S, Furumatsu T, Murase Y, Takigawa M, Oohashi T, Kamioka H, Kubota S
    • Journal Title

      J Cell. Physiol.

      Volume: 233(6) Issue: 6 Pages: 4825-4840

    • DOI

      10.1002/jcp.26285

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H05014, KAKENHI-PROJECT-16H05524, KAKENHI-PROJECT-17H06885, KAKENHI-PROJECT-16K15802, KAKENHI-PROJECT-17K11641, KAKENHI-PROJECT-17H04399, KAKENHI-PROJECT-17K19756
  • [Journal Article] The transcriptional modulator Ifrd1 controls PGC-1α expression under short-term adrenergic stimulation in brown adipocytes2017

    • Author(s)
      Park Gyujin、Horie Tetsuhiro、Kanayama Takashi、Fukasawa Kazuya、Iezaki Takashi、Onishi Yuki、Ozaki Kakeru、Nakamura Yukari、Yoneda Yukio、Takarada Takeshi、Hinoi Eiichi
    • Journal Title

      The FEBS Journal

      Volume: 284 Issue: 5 Pages: 784-795

    • DOI

      10.1111/febs.14019

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H04399, KAKENHI-PROJECT-16H06825
  • [Journal Article] The intrinsic microglial clock system regulates interleukin-6 expression.2017

    • Author(s)
      Ryota Nakazato, Shogo Hotta, Daisuke Yamada, Miki Kou, Saki Nakamura, Yoshifumi Takahata, Hajime Tei, Rika Numano, Akiko Hida, Shigeki Shimba, Michihiro Mieda, Eiichi Hinoi, Yukio Yoneda and Takeshi Takarada
    • Journal Title

      Glia

      Volume: 65 Issue: 1 Pages: 198-208

    • DOI

      10.1002/glia.23087

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PUBLICLY-16H01332, KAKENHI-PUBLICLY-16H01608, KAKENHI-PROJECT-16H05120, KAKENHI-PROJECT-15K15039
  • [Journal Article] Disruption of Bmal1 Impairs Blood?Brain Barrier Integrity via Pericyte Dysfunction2017

    • Author(s)
      Nakazato Ryota、Kawabe Kenji、Yamada Daisuke、Ikeno Shinsuke、Mieda Michihiro、Shimba Shigeki、Hinoi Eiichi、Yoneda Yukio、Takarada Takeshi
    • Journal Title

      The Journal of Neuroscience

      Volume: 37 Issue: 42 Pages: 10052-10062

    • DOI

      10.1523/jneurosci.3639-16.2017

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16KT0192, KAKENHI-PUBLICLY-16H01332, KAKENHI-PUBLICLY-16H01608, KAKENHI-PROJECT-16H05120, KAKENHI-PROJECT-17H06880
  • [Journal Article] Bone Resorption Is Regulated by Circadian Clock in Osteoblasts.2017

    • Author(s)
      Takarada T, Xu C, Ochi H, Nakazato R, Yamada D, Nakamura S, Kodama A, Shimba S, Mieda M, Fukasawa K, Ozaki K, Iezaki T, Fujikawa K, Yoneda Y, Numano R, Hida A, Tei H, Takeda S, Hinoi E.
    • Journal Title

      J Bone Miner Res.

      Volume: 32 Issue: 4 Pages: 872-881

    • DOI

      10.1002/jbmr.3053

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-16H01633, KAKENHI-PROJECT-26713048, KAKENHI-PROJECT-15K15545, KAKENHI-PROJECT-17H04399, KAKENHI-PROJECT-16H06825
  • [Journal Article] Protective upregulation of activating transcription factor-3 against glutamate neurotoxicity in neuronal cells under ischemia.2016

    • Author(s)
      Takeshi Takarada, Miki Kou, Miho Hida, Ryo Fukumori; Saki Nakamura, Takaya Kutsukake, Nobuyuki Kuramoto, Eiichi Hinoi and Yukio Yoneda
    • Journal Title

      J. Neurosci. Res.

      Volume: 94 Issue: 5 Pages: 378-388

    • DOI

      10.1002/jnr.23723

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PUBLICLY-16H01332, KAKENHI-PROJECT-16KT0192
  • [Journal Article] Upregulation of Slc38a1 gene along with promotion of neurosphere growth and subsequent neuronal specification in undifferentiated neural progenitor cells exposed to theanine.2016

    • Author(s)
      Takeshi Takarada, Masato Ogura, Noritaka Nakamichi, Takami Kakuda, Ryota Nakazato, Hiroshi Kokubo, Shinsuke Ikeno, Saki Nakamura, Takaya Kutsukake, Eiichi Hinoi and Yukio Yoneda
    • Journal Title

      Neurochem Res

      Volume: 41 Issue: 1-2 Pages: 5-15

    • DOI

      10.1007/s11064-015-1591-4

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26460387, KAKENHI-PUBLICLY-26117507, KAKENHI-PROJECT-25460092
  • [Journal Article] Circadian Clock Regulates Bone Resorption in Mice. Circadian Clock Regulates Bone Resorption in Mice.2016

    • Author(s)
      Xu C, Ochi H, Fukuda T, Sato S, Sunamura S, Takarada T, Hinoi E, Okawa A, Takeda S.
    • Journal Title

      J Bone Miner Res.

      Volume: - Issue: 7 Pages: 1344-1355

    • DOI

      10.1002/jbmr.2803

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K15543, KAKENHI-PROJECT-25253090, KAKENHI-PROJECT-26893068, KAKENHI-PROJECT-25462381, KAKENHI-PUBLICLY-16H01633, KAKENHI-PROJECT-26713048, KAKENHI-PROJECT-26460387, KAKENHI-PROJECT-15K15545, KAKENHI-PROJECT-16K10847
  • [Journal Article] The transcriptional modulator interferon-related developmental regulator 1 in osteoblasts suppresses bone formation and promotes bone resorption.2016

    • Author(s)
      Takashi Iezaki, Yuki Onishi, Kakeru Ozaki, Kazuya Fukasawa, Yoshifumi Takahata, Yukari Nakamura, Koichi Fujikawa, Takeshi Takarada, Yukio Yoneda and Eiichi Hinoi
    • Journal Title

      Journal of Bone and Mineral Research

      Volume: 31(3) Issue: 3 Pages: 573-84

    • DOI

      10.1002/jbmr.2720

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-13J04206, KAKENHI-PROJECT-14J05326, KAKENHI-PROJECT-26460387
  • [Journal Article] Transcriptional Modulator Ifrd1 Regulates Osteoclast Differentiation through Enhancing the NF-κB/NFATc1 Pathway.2016

    • Author(s)
      Iezaki T, Fukasawa K, Park G, Horie T, Kanayama T, Ozaki K, Onishi Y, Takahata Y, Nakamura Y, Takarada T, Yoneda Y, Nakamura T, Vacher J, Hinoi E.
    • Journal Title

      Mol Cell Biol.

      Volume: 36(19) Issue: 19 Pages: 2451-2463

    • DOI

      10.1128/mcb.01075-15

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H06825, KAKENHI-PROJECT-26460387
  • [Journal Article] ATF3 controls proliferation of osteoclast precursor and bone remodeling.2016

    • Author(s)
      Fukasawa K, Park G, Iezaki T, Horie T, Kanayama T, Ozaki K, Onishi Y, Takahata Y, Yoneda Y, Takarada T, Kitajima S, Vacher J, Hinoi E.
    • Journal Title

      Sci Rep.

      Volume: 6 Issue: 1 Pages: 30918-30918

    • DOI

      10.1038/srep30918

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H06825, KAKENHI-PROJECT-26460387, KAKENHI-PROJECT-15K08300
  • [Journal Article] Genetic analysis of Runx2 function during intramembranous ossification.2016

    • Author(s)
      Takeshi Takarada, Ryota Nakazato, Azusa Tsuchikane, Koichi Fujikawa, Takashi Iezaki, Yukio Yoneda, Eiichi Hinoi
    • Journal Title

      Development

      Volume: 143 Pages: 211-218

    • DOI

      10.1242/dev.128793

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26460387, KAKENHI-PUBLICLY-26117507, KAKENHI-PROJECT-13J04206, KAKENHI-PROJECT-14J05326
  • [Journal Article] Upregulation of runt-related transcription factor-2 through CCAAT enhancer binding protein-beta signaling pathway in microglial BV-2 cells exposed to ATP.2015

    • Author(s)
      Ryota Nakazato*, Takeshi Takarada*, Shinsuke Ikeno, Saki Nakamura, Takaya Kutsukake, Eiichi Hinoi and Yukio Yoneda *Equally contributed.
    • Journal Title

      J Cell Physiol. in press

      Volume: - Issue: 10 Pages: 2510-2521

    • DOI

      10.1002/jcp.24988

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24650196, KAKENHI-PUBLICLY-26117507, KAKENHI-PROJECT-26460387
  • [Journal Article] Daily oral intake of theanine prevents the decline of 5-bromo-2'-deoxyuridine incorporation in hippocampal dentate gyrus with concomitant alleviation of behavioral abnormalities in adult mice with severe traumatic stress.2015

    • Author(s)
      Takeshi Takarada, Noritaka Nakamichi, Takami Kakuda, Ryota Nakazato, Hiroshi Kokubo, Shinsuke Ikeno, Saki Nakamura, Eiichi Hinoi and Yukio Yoneda
    • Journal Title

      J Pharmacol Sci

      Volume: 127 Issue: 3 Pages: 292-297

    • DOI

      10.1016/j.jphs.2014.12.018

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24650196, KAKENHI-PROJECT-25460092, KAKENHI-PUBLICLY-26117507, KAKENHI-PROJECT-26460387, KAKENHI-PROJECT-26670449
  • [Journal Article] Glucose Uptake and Runx2 Synergize to Orchestrate Osteoblast Differentiation and Bone Formation.2015

    • Author(s)
      Jianwen Wei, Junko Shimazu, Munevver P. Makinistoglu, Antonio Maurizi, Daisuke Kajimura, Haihong Zong, Takeshi Takarada, Takashi Iezaki, Jeffrey E. Pessin, Eiichi Hinoi and Gerard Karsenty
    • Journal Title

      Cell

      Volume: 161 Issue: 7 Pages: 1576-1591

    • DOI

      10.1016/j.cell.2015.05.029

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26460387, KAKENHI-PUBLICLY-26117507, KAKENHI-PROJECT-14J05326, KAKENHI-PROJECT-26670449
  • [Journal Article] Potential interactions of calcium-sensitive reagents with zinc ion in different cultured cells.2015

    • Author(s)
      Koichi Fujikawa, Ryo Fukumori, Saki Nakamura, Takaya Kutsukake, Takeshi Takarada and Yukio Yoneda
    • Journal Title

      PLoS ONE

      Volume: 10 Issue: 5 Pages: e0127421-e0127421

    • DOI

      10.1371/journal.pone.0127421

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26460387, KAKENHI-PUBLICLY-26117507, KAKENHI-PROJECT-13J04206
  • [Journal Article] Constitutive and functional expression of runt-related transcription factor-2 by microglial cells.2014

    • Author(s)
      Ryota Nakazato, Takeshi Takarada, Takumi Watanabe, Binh Thanh Nguyen, Shinsuke Ikeno, Eiichi Hinoi, Yukio Yoneda
    • Journal Title

      Neurochemistry International

      Volume: 74 Pages: 24-35

    • DOI

      10.1016/j.neuint.2014.04.010

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-12J02953, KAKENHI-PUBLICLY-26117507, KAKENHI-PROJECT-26460387
  • [Journal Article] Myosin VI reduces proliferation, but not differentiation, in pluripotent P19 cells2013

    • Author(s)
      Takeshi Takarada, Miki Kou, Noritaka Nakamichi, Masato Ogura, Yuma Ito, Ryo Fukumori, Hiroshi Kokubo, Gabriela B. Acosta, Eiichi Hinoi and Yukio Yoneda
    • Journal Title

      PLoS ONE

      Volume: 8 Issue: 5 Pages: e63947-e63947

    • DOI

      10.1371/journal.pone.0063947

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22500330, KAKENHI-PROJECT-24650196, KAKENHI-PROJECT-25460092
  • [Journal Article] An analysis of skeletal development in osteoblast- and chondrocyte-specific Runx2 knockout mice2013

    • Author(s)
      Takeshi Takarada, Eiichi Hinoi, Ryota Nakazato, Hiroki Ochi, Cheng Xu, Azusa Tsuchikane, Shu Takeda, Gerard Karsenty, Takaya Abe, Hiroshi Kiyonari, and Yukio Yoneda
    • Journal Title

      J. Bone Miner. Res

      Volume: 未定 Issue: 10 Pages: 2064-9

    • DOI

      10.1002/jbmr.1945

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22500330, KAKENHI-PROJECT-23689004, KAKENHI-PROJECT-24650196, KAKENHI-PROJECT-24791565
  • [Journal Article] Possible neuroprotective property of nicotinic acetylcholine receptors in association with predominant upregulation of glial cell line-derived neurotrophic factor in astrocytes.2012

    • Author(s)
      Takeshi Takarada, Noritaka Nakamichi, Hirofumi Kawagoe, Masato Ogura, Ryo Fukumori, Ryota Nakazato, Koichi Fujikawa, Miki Kou and Yukio Yoneda
    • Journal Title

      J. Neurosci. Res

      Volume: 90(11) Issue: 11 Pages: 2074-2085

    • DOI

      10.1002/jnr.23101

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22500330, KAKENHI-PROJECT-22590081, KAKENHI-PROJECT-24650196
  • [Journal Article] Positive regulation of osteoclastic differentiation by growth differentiation factor-15 up-regulated in osteocytic cells under hypoxia2012

    • Author(s)
      Eiichi Hinoi, Hiroki Ochi, Takeshi Takarada, Eri Nakatani, Takashi Iezaki, Hiroko Nakajima, Hiroyuki Fujita, Yoshifumi Takahata, Shinya Hidano, Takashi Kobayashi, Shu Takeda, Yukio Yoneda
    • Journal Title

      J Bone Miner Res

      Volume: 4 Issue: 4 Pages: 938-949

    • DOI

      10.1002/jbmr.1538

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-09J03309, KAKENHI-PROJECT-21659018, KAKENHI-PROJECT-22659065, KAKENHI-PROJECT-23689004, KAKENHI-PROJECT-24650196, KAKENHI-PROJECT-24659113
  • [Journal Article] Possible involvement of mitochondrial uncoupling protein-2 in cytotoxicity mediated by acquired N-methyl-D-aspartate receptor channels2012

    • Author(s)
      Fukumori R, Takarada T, Kambe Y, Nakazato R, Fujikawa K & Yoneda Y
    • Journal Title

      Neurochem Int

      Volume: (in press) Issue: 4 Pages: 498-505

    • DOI

      10.1016/j.neuint.2012.03.019

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21659018, KAKENHI-PROJECT-22500330, KAKENHI-PROJECT-24650196
  • [Journal Article] Osteoclastogenesis is negatively regulated by D-serine produced by osteoblasts2012

    • Author(s)
      Takeshi Takarada, Mika Takarada-Iemata, Yoshifumi Takahata, Daisuke Yamada, Tomomi Yamamoto, Yukari Nakamura, Eiichi Hinoi, Yukio Yoneda
    • Journal Title

      J Cell Physiol

      Volume: (in press) Issue: 10 Pages: 3477-87

    • DOI

      10.1002/jcp.24048

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-09J03309, KAKENHI-PROJECT-21659018, KAKENHI-PROJECT-22500330, KAKENHI-PROJECT-23790219, KAKENHI-PROJECT-24650196
  • [Journal Article] Promoted neuronal differentiation after activation of alpha4/beta2 nicotinic acetylcholine receptors in undifferentiated neural progenitors2012

    • Author(s)
      Takeshi Takarada, Noritaka Nakamichi, Seiya Kitajima, Ryo Fukumori, Ryota Nakazato, Nguyen Quynh Le, Yeong-Hun Kim, Koichi Fujikawa, Miki Kou and Yukio Yoneda
    • Journal Title

      PLoS ONE

      Volume: 7 Issue: 10 Pages: e46177-e46177

    • DOI

      10.1371/journal.pone.0046177

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22500330, KAKENHI-PROJECT-22590081, KAKENHI-PROJECT-24650196
  • [Journal Article] Clock genes influence gene expression in growth plate and endochondral ossification in mice2012

    • Author(s)
      Takeshi Takarada, Ayumi Kodama, Shogo Hotta, Michihiro Mieda, Shigeki Shimba, Eiichi Hinoi and Yukio Yoneda
    • Journal Title

      J. Biol.Chem

      Volume: 287 Issue: 43 Pages: 36081-36095

    • DOI

      10.1074/jbc.m112.408963

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22500330, KAKENHI-PROJECT-23590091, KAKENHI-PROJECT-23659134, KAKENHI-PROJECT-24650196
  • [Journal Article] Glutamate preferentially suppresses osteoblastogenesisthan adipogenesis through the cystine/glutamate antiporter in mesenchymal stem cells2011

    • Author(s)
      Mika Takarada-Iemata*, Takeshi Takarada*(*Equally contributed), Yukari Nakamura , Eri Nakatani , Osamu Hori and Yukio Yoneda
    • Journal Title

      J Cell Physiol

      Volume: 226 Issue: 3 Pages: 652-665

    • DOI

      10.1002/jcp.22390

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22500330
  • [Journal Article] NR2-reactive antibody decreases cell viability through augmentation of Ca2+ influx in systemic lupus erythematosus2011

    • Author(s)
      akahisa Gono*, Takeshi Takarada*(*Equally contributed), Ryo Fukumori, Yasushi Kawaguchi, Hirotaka Kaneko, Masanori Hanaoka, Yasuhiro Katsumata, Yukio Yoneda and Hisashi Yamanaka
    • Journal Title

      Arthritis Rheum

      Volume: 63 Issue: 12 Pages: 3952-3959

    • DOI

      10.1002/art.30616

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22500330
  • [Journal Article] A Negative Correlation Between Expression Profiles of Runt-Related Transcription Factor-2 and Cystine/Glutamate Antiporter xCT Subunit in Ovariectomized Mouse Bone2011

    • Author(s)
      Kyosuke Uno
    • Journal Title

      J Pharmacol Sci

      Volume: 115 Issue: 3 Pages: 309-319

    • DOI

      10.1254/jphs.10310FP

    • NAID

      10029892530

    • ISSN
      1347-8613, 1347-8648
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22500330, KAKENHI-PROJECT-22659065
  • [Journal Article] Exacerbated vulnerability to oxidative stress in astrocytic C6 glioma cells with stable overexpression of the glutamine transporter slc38a12011

    • Author(s)
      Masato Ogura, Takeshi Takarada, Noritaka Nakamichi, Hirofumi Kawagoe, Aya Sako, Ryota Nakazato and Yukio Yoneda
    • Journal Title

      Neurochem Int

      Volume: 58 Issue: 4 Pages: 504-511

    • DOI

      10.1016/j.neuint.2011.01.007

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22500330
  • [Journal Article] γ-aminobutyric acid, type B receptors negatively regulate osteoblast ogenesis toward disturbance of osteoclastogenesis mediated by receptor activator of nuclear factor κB ligand in mouse bone2011

    • Author(s)
      Yoshifumi Takahata, Takeshi Takarada, Eiichi Hinoi, Yukari Nakamura, Hiroyuki Fujita, Yukio Yoneda
    • Journal Title

      J Biol Chem

      Volume: 286 Issue: 38 Pages: 32906-32917

    • DOI

      10.1074/jbc.m111.253526

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-09J03309, KAKENHI-PROJECT-21659018, KAKENHI-PROJECT-22500330
  • [Journal Article] Selective downregulation of N-methyl-D-aspartate receptor (NMDAR) rather than non-NMDAR subunits in ipsilateral cerebral hemispheres in rats with middle cerebral artery occlusion2011

    • Author(s)
      Takeshi Takarada
    • Journal Title

      Jpn J Neuropsychopharmacol

      Volume: 31 Pages: 187-194

    • NAID

      10029565167

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22500330
  • [Journal Article] Negative regulation of osteoblastogenesis through downregulation of runt-related transcription factor-2 in osteoblastic MC3T3-E1 cells with stable overexpression of the cystine/glutamate antiporter xCT subunit2011

    • Author(s)
      Kyosuke Uno, Takeshi Takarada, Mika Takarada-Iemata, Yukari Nakamura, Hiroyuki Fujita, Eiichi Hinoi and Yukio Yoneda
    • Journal Title

      J Cell Physiol

      Volume: 226 Issue: 11 Pages: 2953-2964

    • DOI

      10.1002/jcp.22642

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22500330, KAKENHI-PROJECT-22659065
  • [Journal Article] Induced tolerance to glutamate neurotoxicity through downregulation of NR2 subunits of N-methyl-D-aspartate receptors in cultured rat striatal neurons.2010

    • Author(s)
      Yuki Kambe, Noritaka Nakamichi, Takeshi Takarada, Ryo Fukumori, Yukio Yoneda
    • Journal Title

      J.Neurosci. Res.

      Volume: 88 Pages: 2177-2187

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22500330
  • [Journal Article] Preferential inhibition by antidiarrheic 2-methoxy-4-methylphenol of Ca2+ influx across acquired N-methyl-D-aspartate receptor channels composed of NR1/NR2B subunit assembly.2010

    • Author(s)
      Noritaka Nakamichi*, Ryo Fukumori*, Takeshi Takarada, Yuki Kambe, Tomomi, Yamamoto, Nobuyuki Matsushima, Nobuaki Moriguchi, Yukio Yoneda
    • Journal Title

      J. Neurosci. Res. (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790250
  • [Journal Article] Induced tolerance to glutamate neurotoxicity through downregulation of NR2 subunits of N-methyl-D-aspartate receptors in cultured rat striatal neurons.2010

    • Author(s)
      Yuki Kambe, Noritaka Nakamichi, Takeshi Takarada, Ryo Fukumori, Yukio Yoneda
    • Journal Title

      J.Neurosci.Res. (掲載確定)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790250
  • [Journal Article] Glutamate preferentially suppresses osteoblastogenesisthan adipogenesis through the cystine/glutamate antiporter in mesenchymal stem cells.2010

    • Author(s)
      Mika Takarada-lemata, Takeshi Takarada, Yukari Nakamura,Eri Nakatani,Osamu Hori, Yukio Yoneda
    • Journal Title

      J.Cell. Physiol.

      Volume: 226 Pages: 652-665

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22500330
  • [Journal Article] Induced tolerance to glutamate neurotoxicity through downregulation of NR2 subunits of N-methyl-D-aspartate receptors in cultured rat striatal neurons.2010

    • Author(s)
      Yuki Kambe, Noritaka Nakamichi, Takeshi Takarada, Ryo Fukumori, Yukio Yoneda
    • Journal Title

      J. Neurosci. Res. (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790250
  • [Journal Article] Preferential inhibition by antidiarrheic 2-methoxy-4-methylphenol of Ca^<2+> influx across acquired N-methyl-D-aspartate receptor channels composed of NR1/NR2B subunit assembly.2010

    • Author(s)
      Noritaka Nakamichi, Ryo Fukumori, Takeshi Takarada, Yuki Kambe, Tomomi, Yamamoto, Nobuyuki Matsushima, Nobuaki Moriguchi, Yukio Yoneda
    • Journal Title

      J.Neurosci.Res. (掲載確定)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790250
  • [Journal Article] Requirement of both NR3A and NR3B subunits for dominant negative properties on Cat+,mobilization mediated by acquired N-methyl-D-aspartate receptor channels into mitochondria.2010

    • Author(s)
      Ryo Fukumori, Takeshi Takarada, Noritaka Nakamichi, Yuki Kambe, Hirofumi Kawagoe, Ryota Nakazato, Yukio Yoneda
    • Journal Title

      Neurochem Int

      Volume: 57 Pages: 730-737

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22500330
  • [Journal Article] Inhibition by 2-methoxy-4-ethylphenol of Ca2+ influx through acquired and native N-methyl-D-aspartate receptor channels.2010

    • Author(s)
      Ryo Fukumori*, Noritaka Nakamichi*, Takeshi Takarada, Yuki Kambe, Nobuyuki Matsushima, Nobuaki Moriguchi, Yukio Yoneda
    • Journal Title

      J. Pharmacol. Sci. 112

      Pages: 273-281

    • NAID

      10027744270

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790250
  • [Journal Article] Inhibition by 2-methoxy-4-ethylphenol of Ca^<2+> influx through acquired and native N-methyl-D-aspartate receptor channels.2010

    • Author(s)
      Ryo Fukumori*, Noritaka Nakamichi*, Takeshi Takarada, Yuki Kambe, Nobuyuki Matsushima, Nobuaki Moriguchi, Yukio Yoneda
    • Journal Title

      J.Pharmacol.Sci. (掲載確定)

    • NAID

      10027744270

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790250
  • [Journal Article] Preferential inhibition by antidiarrheic 2-methoxy-4-methylphenol of Ca^<2+> influx across acquired N-methyl-D-aspartate receptor channels composed of NR1/NR2B subunit assembly2010

    • Author(s)
      Noritaka Nakamichi, Ryo Fukumori, Takeshi Takarada, Yuki Kambe, Tomomi, Yamamoto, Nobuyuki Matsushima, Nobuaki Moriguchi, Yukio Yoneda
    • Journal Title

      J.Neurosci. Res.

      Volume: 88 Pages: 2483-2493

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22500330
  • [Journal Article] Inhibition by 2-methoxy-4-ethylphenol of Ca^<2+> influx through acquiredand native N-methyl-D-aspartate receptor channels.2010

    • Author(s)
      Ryo Fukumori, Noritaka Nakamichi, Takeshi Takarada, Yuki Kambe, Nobuyuki Matsushima, Nobuaki Moriguchi, Yukio Yoneda
    • Journal Title

      J.Pharmacol. Sci.

      Volume: 112 Pages: 273-281

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22500330
  • [Journal Article] NMDA受容体のポリアミン部位と神経突起の伸長.2009

    • Author(s)
      宝田剛志, 米田幸雄
    • Journal Title

      生体の科学 60

      Pages: 368-369

    • Data Source
      KAKENHI-PROJECT-20790250
  • [Journal Article] Possible promotion of neuronal differentiation in fetal rat brain neural progenitor cells after sustained exposure to static magnetism2009

    • Author(s)
      Noritaka Nakamichi, Yukichi Ishioka, Takao Hirai, Shusuke Ozawa, Masaki Tachibana, Nobuhiro Nakamura, Takeshi Takarada and Yukio Yoneda
    • Journal Title

      J Neurosci Res (掲載確定)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790250
  • [Journal Article] Transactivation by runt related factor-2 of matrix metalloproteinase-13 in astrocytes.2009

    • Author(s)
      Takeshi Takarada, Yukio Yoneda
    • Journal Title

      Neurosci Lett 451

      Pages: 99-104

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790250
  • [Journal Article] Possible promotion of neuronal differentiation in fetal rat brain neural progenitor cells after sustained exposure to static magnetism.2009

    • Author(s)
      Noritaka Nakamichi, Yukichi Ishioka, Takao Hirai, Shusuke Ozawa, Masaki Tachibana, Nobuhiro Nakamura, Takeshi Takarada, Yukio Yoneda
    • Journal Title

      J Neurosci Res 87

      Pages: 2406-2417

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790250
  • [Journal Article] Predominant promotion by tacrolimus of chondrogenic differentiation to proliferating chondrocytes.2009

    • Author(s)
      Yukari Nakamura, Takeshi Takarada, Ayumi Kodama, Eiichi Hinoi, Yukio Yoneda
    • Journal Title

      J Pharwacol Sci 109

      Pages: 413-423

    • NAID

      10025735254

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790250
  • [Journal Article] Possible protection by notoginsenoside R1 against neurotoxicity of N-methyl-D-aspartate receptor composed of an NR1/NR2B heteromeric assembly2009

    • Author(s)
      Bin Gu, Noritaka Nakamichi, Wen-Sheng Zhang, Yukary Nakamura, Yuki Kambe, Ryo Fukumori, Kazuhiro Takuma, Kiyofumi Yamada, Takeshi Takarada, Hideo Taniura and Yukio Yoneda
    • Journal Title

      J Neurosci Res (掲載確定)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790250
  • [Journal Article] Predominant promotion by tacrolimus of chondrogenic differentiation to proliferating chondrocytes2009

    • Author(s)
      Yukari Nakamura, Takeshi Takarada, Ayumi Kodama, Eiichi Hinoi and Yukio Yoneda
    • Journal Title

      J Pharmacol Sci in press (掲載確定)

    • NAID

      10025735254

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790250
  • [Journal Article] A protein-protein interaction of stress-responsive myosin VI endowed to inhibit neural progenitor self-replication with RNA binding protein, TLS, in murine hippocampus.2009

    • Author(s)
      Takeshi Takarada*, Keisuke Tamaki*, Toru Takumi, Masato Ogura, Yuma Ito, Noritaka Nakamichi, Yukio Yoneda
    • Journal Title

      J Neurochem 110

      Pages: 1457-1468

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790250
  • [Journal Article] Interference with cellular differentiation by D-serine through antagonism at N-methyl-D-aspartate receptors composed of NR1 and NR3A subunits in chondrocytes.2009

    • Author(s)
      Takeshi Takarada, Yoshifumi Takahata, Mika Iemata, Eiichi Hinoi, Kyosuke Uno, Takao Hirai, Tomomi Yamamoto, Yukio Yoneda
    • Journal Title

      J Cell Physiol 220

      Pages: 756-764

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790250
  • [Journal Article] Interference by adrenaline with chondrogenic differentiation through suppression of gene transactivation mediated by Sox9 family members.2009

    • Author(s)
      Takeshi Takarada, Hironori Hojo, Mika Iemata, Koichi Sahara, Ayumi Kodama, Nobuhiro Nakamura, Eiichi Hinoi, Yukio Yoneda
    • Journal Title

      Bone 45

      Pages: 568-578

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790250
  • [Journal Article] Neurogenesis mediated by GABA and glutamate signaling2009

    • Author(s)
      Noritaka Nakamichi, Takeshi Takarada and Yukio Yoneda
    • Journal Title

      J Pharmacol Sci (掲載確定)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790250
  • [Journal Article] Predominant promotion by tacrolimus of chondrogenic differentiation to proliferating chondrocytes.2009

    • Author(s)
      Yukari Nakamura*, Takeshi Takarada*, Ayumi Kodama, Eiichi Hinoi, Yukio Yoneda
    • Journal Title

      J Pharmacol Sci 109

      Pages: 413-423

    • NAID

      10025735254

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790250
  • [Journal Article] Transactivation by runt related factor-2 of matrix metalloproteinase-13 in astrocytes2009

    • Author(s)
      Takeshi Takarada and Yukio Yoneda
    • Journal Title

      Neurosci Lett 451

      Pages: 99-104

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790250
  • [Journal Article] A protein-protein interaction of stress-responsive myosin VI endowed to inhibit neural progenitor self-replication with RNA binding protein, TLS, in murine hippocampus.2009

    • Author(s)
      Takeshi Takarada, Keisuke Tamaki, Toru Takumi, Masato Ogura, Yuma Ito, Noritaka Nakamichi, Yukio Yoneda
    • Journal Title

      J Neurochem 110

      Pages: 1457-1468

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790250
  • [Journal Article] Possible protection by notoginsenoside R1 against neurotoxicity of N-methyl-D-aspartate receptor composed of an NR1/NR2B heteromeric assembly.2009

    • Author(s)
      Bin Gu*, Noritaka Nakamichi*, Wen-Sheng Zhang, Yukary Nakamura, Yuki Kambe, Ryo Fukumori, Kazuhiro Takuma, Kiyofumi Yamada, Takeshi Takarada, Hideo Taniura, Yukio Yoneda
    • Journal Title

      J Neurosci Res 87

      Pages: 2145-2156

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790250
  • [Journal Article] 未分化神経細胞における繊毛性神経栄養因子(CNTF)受容体のGABA_A受容体による発現増.2009

    • Author(s)
      宝田剛志, 米田幸雄
    • Journal Title

      生体の科学 60

      Pages: 384-385

    • Data Source
      KAKENHI-PROJECT-20790250
  • [Journal Article] 代謝調節型グルタミン酸受容体のサブタイプ2009

    • Author(s)
      宝田剛志, 米田幸雄
    • Journal Title

      生体の科学 60

      Pages: 358-359

    • Data Source
      KAKENHI-PROJECT-20790250
  • [Journal Article] A critical importance of polyamine site in NMDA receptors for neurite outgrowth and fasciculation at early stages of P19 neuronal differentiation2008

    • Author(s)
      Danko D. Georgiev, Hideo Taniura, Yuki Kambe, Takeshi Takarada, Yukio Yoneda
    • Journal Title

      Exp Cell Res 314

      Pages: 2603-2617

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790250
  • [Journal Article] Functional expression of beta2 adrenergic receptors responsible for protection against oxidative stress through promotion of glutathione synthesis after Nrf2 upregulation in undifferentiated mesenchymal C3H10T1/2 stem cells.2008

    • Author(s)
      Yoshifumi Takahata*, Takeshi Takarada*, Mika Iemata, Tomomi Yamamoto, Yukary Nakamura, Ayumi Kodama, Yukio Yoneda
    • Journal Title

      J Cell Physiol 218

      Pages: 268-275

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790250
  • [Journal Article] Functional expression of beta2 adrenergic receptors responsiblefor protection against oxidative stress through promotion of glutathione synthesis after Nrf2 upregulation in undifferentiated mesenchymal C3H10T1/2 stem cells2008

    • Author(s)
      Yoshifumi Takahata, Takeshi Takarada, Mika lemata, Tomomi Yamamoto, Yukary Nakamura, Ayumi Kodama and Yukio Yoneda
    • Journal Title

      J Cell Physiol 218

      Pages: 268-275

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790250
  • [Journal Article] Differential regulation by glycine of cellular maturation in chondrocytes and osteoblasts2008

    • Author(s)
      Takahata Y, Takarada T, Osawa M, Hinoi E, Nakamura Y, Yoneda Y
    • Journal Title

      Cell and Tissue Research (In press)

    • Data Source
      KAKENHI-PROJECT-18053009
  • [Journal Article] Differential regulation of cellular maturation in chondrocytes and osteoblasts by glycine.2008

    • Author(s)
      Yoshifumi Takahata, Takeshi Takarada*, Masato Osawa, Eiichi Hinoi, Yukari Nakamura, Yukio Yoneda
    • Journal Title

      Cell Tissue Res 333

      Pages: 91-103

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790250
  • [Journal Article] A critical importance of polyamine site in NMDA receptors for neurite outgrowth and fasciculation at early stages of P19 neuronal differentiation2008

    • Author(s)
      Danko D. Georgiev, Hideo Taniura, Yuki Kambe, Takeshi Takarada & Yukio Yoneda
    • Journal Title

      Exp Cell Res 314

      Pages: 2603-2617

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790250
  • [Journal Article] Suppression by glutamate of proliferative activity through glutathione depletion mediated by cystine/glutamate antiporter in mesenchymal C3H10T1/2 stem cells.2007

    • Author(s)
      Iemata M, Takarada T, Hinoi E, Taniura H, Yoneda Y
    • Journal Title

      Journal of Cellular Physiology 213

      Pages: 721-729

    • Data Source
      KAKENHI-PROJECT-18053009
  • [Journal Article] Glutamate suppresses osteoclastogenesis through the cystine/glutamate antiporter2007

    • Author(s)
      Hinoi E, Takarada T, Uno K, Inoue M, Murafuji Y, Yoneda Y
    • Journal Title

      American Journal of Pathology 170

      Pages: 1277-1290

    • Data Source
      KAKENHI-PROJECT-18053009
  • [Journal Article] Nuclear factor E2 p45-related factor 2 negatively regulates chondrogenesis.2007

    • Author(s)
      Eiichi Hinoi, Takeshi Takarada, Sayumi Fujimori, Liyang Wang, Mika lemata, Kyosuke Uno, Yukio Yoneda
    • Journal Title

      Bone 40

      Pages: 337-344

    • Data Source
      KAKENHI-PROJECT-17790057
  • [Journal Article] Oral administration of phenolic antidiarrheic ingredients prevents ovariectomy-induced bone loss.2007

    • Author(s)
      Nobuaki Moriguchi, Eiichi Hinoi, Takeshi Takarada, Nobuyuki Matsushima, Kyosuke Uno, Yukio Yoneda
    • Journal Title

      Biochemical Pharmacology 73

      Pages: 385-393

    • Data Source
      KAKENHI-PROJECT-17790057
  • [Journal Article] Oral administration of phenolic antidiarrheic ingredients prevents ovariectomy-induced bone loss.2007

    • Author(s)
      Moriguchi N, Hinoi E, Takarada T, Matsushima N, Uno K, Yoneda Y
    • Journal Title

      Biochemical Pharmacology 73

      Pages: 385-393

    • Data Source
      KAKENHI-PROJECT-18053009
  • [Journal Article] Serine racemase suppresses chondrogenic differentiation in cartilage in a Sox9-dependent manner.2007

    • Author(s)
      Takarada T, Hinoi E, Takahata Y, Yoneda Y
    • Journal Title

      Journal of Cellular Physiology 215

      Pages: 320-328

    • Data Source
      KAKENHI-PROJECT-18053009
  • [Journal Article] Nuclear factor E2 p45-related factor 2 negatively regulates chondrogenesis.2007

    • Author(s)
      Hinoi E, Takarada T, Fujimori S, Wang L, lemata M, Uno K, Yonerda Y
    • Journal Title

      Bone 40

      Pages: 337-344

    • Data Source
      KAKENHI-PROJECT-18053009
  • [Journal Article] Osteoblast protects osteoclast devoid of sodium-dependent vitamin C transporters from oxidative cytotoxicity of ascorbic acid.2007

    • Author(s)
      Takarada T, Hinoi E, Kambe Y, Sahara K, Kurokawa K, Takahata Y, Yoneda Y
    • Journal Title

      European journal of Pharmacology 575

      Pages: 1-11

    • Data Source
      KAKENHI-PROJECT-18053009
  • [Journal Article] Glutamate is a determinant of cellular proliferation through modulation of nuclear factor E2 p45-related factor-2 expression in osteoblastic MC3T3-E1 cells.2007

    • Author(s)
      Uno K, Takarada T, Hinoi E, Yoneda Y
    • Journal Title

      Journal of Cellular Physiology 213

      Pages: 105-114

    • Data Source
      KAKENHI-PROJECT-18053009
  • [Journal Article] Glutamate suppresses osteoclastogenesis through the cystine/glutamate antiporter.2007

    • Author(s)
      Eiichi Hinoi, Takeshi Takarada, Kyousuke Uno, Maki Inoue, Yashuhiro Murafuji, Yukio Yoneda
    • Journal Title

      American Journal of Pathology 170

      Pages: 1277-1290

    • Data Source
      KAKENHI-PROJECT-17790057
  • [Journal Article] Upregulation of per mRNA expression by PTH through a PKA-CREB-dependent mechanism in chondrocytes.2006

    • Author(s)
      Eiichi Hinoi, Taichi Ueshima, Hironori Hojo, Mika lemata, Takeshi Takarada, Yukio Yoneda
    • Journal Title

      Journal of Biological Chemistry 281

      Pages: 23632-23642

    • Data Source
      KAKENHI-PROJECT-17790057
  • [Journal Article] Possible expression of a particular gamma-aminobutyric acid transporter isoform responsive to upregulation byhyperosmolarity in rat calvarial osteoblasts.2006

    • Author(s)
      Sayumi Fujimori, Eiichi Hinoi, Takeshi Takarada, Mika lemata, Yoshifumi Takahata, Yukio Yoneda
    • Journal Title

      European Journal of Pharmacology 550

      Pages: 24-32

    • Data Source
      KAKENHI-PROJECT-17790057
  • [Journal Article] A molecular mechanism of pyruvate protection against cytotoxicity of reactive oxygen species in osteoblasts.2006

    • Author(s)
      Eiichi Hinoi, Takeshi Takarada, Yuriko Tsuchihashi, Sayumi Fujimori, Nobuaki Moriguchi, Liyang Wang, Kyosuke Uno, Yukio Yoneda
    • Journal Title

      Molecular Pharmacology 70

      Pages: 925-935

    • Data Source
      KAKENHI-PROJECT-17790057
  • [Patent] 神経細胞とグリア細胞を共培養する方法2011

    • Inventor(s)
      米田幸雄、宝田剛志
    • Industrial Property Number
      2011-154155
    • Filing Date
      2011-07-12
    • Data Source
      KAKENHI-PROJECT-22500330
  • [Patent] 神経細胞新生促進組成物2010

    • Inventor(s)
      米田幸雄、宝田剛志、川越博文
    • Industrial Property Rights Holder
      金沢大学
    • Industrial Property Number
      2010-254320
    • Filing Date
      2010-11-12
    • Data Source
      KAKENHI-PROJECT-22500330
  • [Patent] NMDA受容体阻害剤2007

    • Inventor(s)
      米田 幸雄 中道 範隆 寳田 剛志 松島 伸行 森口 展明 柴田 仁
    • Industrial Property Rights Holder
      金沢大学
    • Industrial Property Number
      2007-138453
    • Filing Date
      2007
    • Data Source
      KAKENHI-PROJECT-18053009
  • [Patent] 骨代謝性疾患治療薬スクリーニングシステムの開発2006

    • Inventor(s)
      米田 幸雄 寳田 剛志 宇野 恭介
    • Industrial Property Rights Holder
      金沢大学
    • Industrial Property Number
      2006-000038
    • Filing Date
      2006
    • Data Source
      KAKENHI-PROJECT-18053009
  • [Presentation] PRRX1-TOP2A interaction is a malignancy-promoting factor in human malignant peripheral nerve sheath tumours.2023

    • Author(s)
      Takihira S, Yamada D, Osone T, Takao T, Sakaguchi M,, Nakata E, Ozaki T, Takarada T.
    • Organizer
      アメリカがん学会
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K09401
  • [Presentation] iPS細胞技術を利用したヒト四肢骨格発生過程の理解と、再生医療への応用2023

    • Author(s)
      宝田剛志
    • Organizer
      第95回日本組織培養学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-23K21368
  • [Presentation] ヒトiPS細胞由来肢芽間葉系細胞の発生機序の検討2023

    • Author(s)
      髙尾知佳、大曽根達則 、山田大祐、中田英二、尾﨑敏文、宝田剛志
    • Organizer
      第38回日本整形外科学会基礎学術集会
    • Data Source
      KAKENHI-PROJECT-23K08677
  • [Presentation] Production of hyaline cartilage sheet using human induced pluripotent stem cell-derived chondrocyte precursor cells2023

    • Author(s)
      Tomoka Takao, Masato Sato, Eriko Toyoda, Yuki Fujisawa, Daisuke Yamada, Eiji Nakata, Toshifumi Ozaki, Takeshi Takarada
    • Organizer
      第95回日本組織培養学会
    • Data Source
      KAKENHI-PROJECT-23K08677
  • [Presentation] ヒトiPS細胞由来肢芽間葉系細胞を用いた ヒト肢芽発生機序の検討2023

    • Author(s)
      髙尾知佳、大曽根達則 、山田大祐、中田英二、尾﨑敏文、宝田剛志
    • Organizer
      第23回日本再生医療学会総会
    • Data Source
      KAKENHI-PROJECT-23K08677
  • [Presentation] 四肢骨格の発生過程を利用したヒト軟骨再生研究2023

    • Author(s)
      宝田剛志
    • Organizer
      第96回日本整形外科学会学術総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-23K21368
  • [Presentation] Understanding of human limb development using iPSCs2023

    • Author(s)
      Tomoka Takao, Tatsunori Osone, Daisuke Yamada, Eiji Nakata, Toshifumi Ozaki, Takeshi Takarada
    • Organizer
      第36回日本軟骨代謝学会
    • Data Source
      KAKENHI-PROJECT-23K08677
  • [Presentation] ヒト多能性幹細胞を利用した運動器の医学研究2022

    • Author(s)
      宝田剛志
    • Organizer
      第6回リハビリテーション医学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-23K21368
  • [Presentation] 青色光/細胞種特異的なDNA組み換え反応を可能とするTRE-PA-Creノックインマウスの開発2022

    • Author(s)
      櫃本有希雄、髙尾知佳、山田大祐、平岡優一、田中光一、佐藤守俊、宝田剛志
    • Organizer
      第45回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-20K21373
  • [Presentation] 骨系統疾患特異的iPS由来ヒト肢芽間葉系細胞を用いたハイスループット薬剤スクリーニングシムテムの構築2022

    • Author(s)
      山田大祐, 髙尾知佳, 中村正裕, Ming Lu, 戸口田淳也, 宝田剛志
    • Organizer
      第95回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-21K07192
  • [Presentation] ヒト多能性幹細胞からの軟骨前駆細胞の誘導と、その拡大培養方法の開発2022

    • Author(s)
      山田大祐、髙尾知佳、中村正裕、Ming Lu 、戸口田淳也、宝田剛志
    • Organizer
      第34回日本軟骨代謝学会
    • Data Source
      KAKENHI-PROJECT-21K07192
  • [Presentation] ヒト多能性幹細胞に由来する分化指向性間葉系前駆細胞集団の選別単離方法の開発と、その医学応用2021

    • Author(s)
      宝田 剛志
    • Organizer
      第124回岡山県医用工学研究会
    • Data Source
      KAKENHI-PROJECT-23K21368
  • [Presentation] ヒト多能性幹細胞からの軟骨前駆細胞の誘導と、その拡大培養方法の開発2021

    • Author(s)
      山田大祐、髙尾知佳、中村正裕、Ming Lu 、戸口田淳也、宝田剛志
    • Organizer
      第36回日本整形外科学会基礎学術集会
    • Data Source
      KAKENHI-PROJECT-21K07192
  • [Presentation] マウス四肢骨格発生過程の一細胞遺伝子発現解析2021

    • Author(s)
      髙尾知佳, 明路, 山田大祐, 北條宏徳, 宝田剛志
    • Organizer
      第39回日本骨代謝学会
    • Data Source
      KAKENHI-PROJECT-20K21373
  • [Presentation] ヒト多能性幹細胞から肢芽間葉系細胞への分化誘導技術の開発2021

    • Author(s)
      明路, 山田大祐, 髙尾知佳, 中村正裕, 戸口田淳也, 宝田剛志
    • Organizer
      第44回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-23K21368
  • [Presentation] Postnatal global deletion of the aggrecan gene impairs endochondral ossification2019

    • Author(s)
      Kei Ishibashi, Hidemi Torihara, Mitsuaki Ono, Emilio Satoshi Hara, Midori Edamatsu, Tomoko Yonezawa, Shuji Nosho, Ikue Tosa, Takeshi Takarada, Takuo Kuboki, Attila Aszodi, Hiroshi Kamioka, Toshitaka Oohashi
    • Organizer
      11th international conference on proteoglycans in Kanazawa
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03842
  • [Presentation] Dissecting the hierarchy and lineage of mesenchymal stem cells by mouse genetics.2018

    • Author(s)
      Takeshi Takarada
    • Organizer
      International Symposium on Immunology and Tissue Regeneration in Okayama / 12th URA International Symposium
    • Data Source
      KAKENHI-PROJECT-17H04399
  • [Presentation] 組織機能修復・再生・創薬を指向した間葉系幹細胞の幹細胞の階層性/系譜の分子理解2018

    • Author(s)
      宝田 剛志
    • Organizer
      第29回創薬・薬理フォーラム岡山
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04399
  • [Presentation] 精神/疼痛の恒常性維持基盤における体内時計システムの役割2017

    • Author(s)
      宝田剛志
    • Organizer
      第1回感覚免疫学研究会(生理学研究所研究会)
    • Invited
    • Data Source
      KAKENHI-PROJECT-16KT0192
  • [Presentation] 間葉系幹細胞の階層性・系譜の分子理解と骨疾患への応用2017

    • Author(s)
      宝田 剛志
    • Organizer
      第54回ネフロンフォーラム
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04399
  • [Presentation] 骨組織再生材料開発を指向した骨格形成過程の階層性・系譜の分子理解2017

    • Author(s)
      宝田 剛志
    • Organizer
      日本バイオマテリアル学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04399
  • [Presentation] 創薬・再生医療を指向した幹細胞の階層法/系譜の分子理解2017

    • Author(s)
      宝田 剛志
    • Organizer
      第90回日本薬理学会年会
    • Place of Presentation
      長崎ブリックホール
    • Invited
    • Data Source
      KAKENHI-PROJECT-26460387
  • [Presentation] 骨格形成過程における細胞集団不均一性の理解2017

    • Author(s)
      宝田 剛志
    • Organizer
      第5回細胞凝集研究会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04399
  • [Presentation] 精神/疼痛の恒常性維持基盤における体内時計システムの役割2017

    • Author(s)
      宝田 剛志
    • Organizer
      第1回感覚免疫学研究会
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-16H01332
  • [Presentation] 間葉系幹細胞の階層性・系譜の分子理解と応用2017

    • Author(s)
      宝田 剛志
    • Organizer
      第26回硬組織再生生物学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04399
  • [Presentation] 生体内での間葉系幹細胞系譜の分子理解と、その応用2017

    • Author(s)
      宝田 剛志
    • Organizer
      日本薬学会第138年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04399
  • [Presentation] 組織機能修復を指向した間葉系幹細胞の細胞生物学的特徴づけ2016

    • Author(s)
      宝田 剛志
    • Organizer
      第153回ECM Society、第2回 Craniofacial and Stem Cell Biology Seminar
    • Place of Presentation
      岡山大学歯学部
    • Invited
    • Data Source
      KAKENHI-PROJECT-26460387
  • [Presentation] 組織再生を指向した間葉系幹細胞の細胞生物学的特徴づけ2016

    • Author(s)
      宝田 剛志
    • Organizer
      組織再生セミナー(京都大学再生医科学研究所)
    • Place of Presentation
      京都大学再生医科学研究所
    • Invited
    • Data Source
      KAKENHI-PROJECT-26460387
  • [Presentation] 遺伝子改変マウスを利用した生体内間葉系幹細胞の階層性の理解2016

    • Author(s)
      宝田 剛志
    • Organizer
      第72回岡山実験動物研究会例会
    • Place of Presentation
      岡山大学医学部
    • Invited
    • Data Source
      KAKENHI-PROJECT-26460387
  • [Presentation] The role of Runx2 in endochondral and intramembranous ossification during skeletogenesis.2015

    • Author(s)
      Takeshi Takarada
    • Organizer
      The 3rd Seoul Symposium on Bone Health
    • Place of Presentation
      Seoul (Korea)
    • Year and Date
      2015-05-28
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-26117507
  • [Presentation] 緑茶アミノ酸テアニンによる神経系前駆細胞の機能制御2015

    • Author(s)
      宝田 剛志
    • Organizer
      生体機能と創薬シンポジウム2015
    • Place of Presentation
      千葉
    • Year and Date
      2015-08-28
    • Invited
    • Data Source
      KAKENHI-PROJECT-26460387
  • [Presentation] 緑茶アミノ酸テアニンによる神経系前駆細胞の機能制御2015

    • Author(s)
      宝田 剛志
    • Organizer
      生体機能と創薬シンポジウム2015
    • Place of Presentation
      千葉
    • Year and Date
      2015-08-28
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-26117507
  • [Presentation] 体内時計によるグリアネットワーク調節に注目した「精神-疼痛」連関メカニズムの解明2015

    • Author(s)
      宝田 剛志
    • Organizer
      新学術領域研究「グリアアセンブリによる脳機能発現の制御と病態」2014年度班会議
    • Place of Presentation
      東京
    • Year and Date
      2015-01-24
    • Data Source
      KAKENHI-PUBLICLY-26117507
  • [Presentation] The role of Runx2 in endochondral and intramembranous ossification during skeletogenesis.2015

    • Author(s)
      Takeshi Takarada
    • Organizer
      The 3rd Seoul Symposium on Bone Health
    • Place of Presentation
      Seoul (Korea)
    • Year and Date
      2015-05-28
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26460387
  • [Presentation] 脳梗塞後神経細胞障害におけるグルタミントランスポーターSlc38a1の役割2014

    • Author(s)
      宝田 剛志、中里 亮太、中村 早希、藤川 晃一、高 巳奇、檜井 栄一、米田 幸雄
    • Organizer
      第126回日本薬理学会近畿部会
    • Place of Presentation
      和歌山
    • Year and Date
      2014-10-24
    • Data Source
      KAKENHI-PUBLICLY-26117507
  • [Presentation] 骨関節組織におけるアミノ酸シグナルの役割2014

    • Author(s)
      宝田 剛志
    • Organizer
      福島県立医科大学研究連携セミナー2014
    • Place of Presentation
      福島
    • Year and Date
      2014-07-04
    • Invited
    • Data Source
      KAKENHI-PROJECT-26460387
  • [Presentation] 脳梗塞後神経細胞障害におけるグルタミントランスポーターSlc38a1の役割2014

    • Author(s)
      宝田 剛志、中里 亮太、中村 早希、藤川 晃一、高 巳奇、檜井 栄一、米田 幸雄
    • Organizer
      第126回日本薬理学会近畿部会
    • Place of Presentation
      和歌山
    • Year and Date
      2014-10-24
    • Data Source
      KAKENHI-PROJECT-26460387
  • [Presentation] ミクログリア時計システムの入出力機構に関する解析2014

    • Author(s)
      宝田 剛志
    • Organizer
      包括脳ネットワーク2014年冬のシンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2014-12-12
    • Data Source
      KAKENHI-PUBLICLY-26117507
  • [Presentation] アミノ酸シグナルによる骨格維持機構2013

    • Author(s)
      宝田 剛志
    • Organizer
      日本薬学会第133年会
    • Place of Presentation
      パシフィコ横浜(神奈川県)
    • Invited
    • Data Source
      KAKENHI-PROJECT-22500330
  • [Presentation] グルタミン酸神経毒性を規定するミトコンドリア因子2013

    • Author(s)
      宝田剛志、福森良、米田幸雄
    • Organizer
      第86回日本薬理学会年会
    • Place of Presentation
      福岡国際会議場(福岡県)
    • Data Source
      KAKENHI-PROJECT-22500330
  • [Presentation] グルタミン酸神経毒性を規定するミトコンドリア因子2013

    • Author(s)
      宝田 剛志
    • Organizer
      第86回日本薬理学会年会
    • Place of Presentation
      福岡国際会議場(福岡県)
    • Invited
    • Data Source
      KAKENHI-PROJECT-22500330
  • [Presentation] アミノ酸シグナルによる骨格維持機構2013

    • Author(s)
      宝田剛志
    • Organizer
      日本薬学会第133年会
    • Place of Presentation
      パシフィコ横浜(神奈川県)
    • Data Source
      KAKENHI-PROJECT-22500330
  • [Presentation] グルタミン酸トランスポーターの転写制御因子Runx2による調節機構2012

    • Author(s)
      宝田剛志
    • Organizer
      第7回トランスポーター研究会年会/JTRA2012
    • Place of Presentation
      京都大学(京都府)
    • Year and Date
      2012-06-10
    • Data Source
      KAKENHI-PROJECT-22500330
  • [Presentation] ミクログリア細胞における時計遺伝子の機能解析2012

    • Author(s)
      宝田剛志, 堀田彰悟, 棒葉繁紀, 米田幸雄
    • Organizer
      生体機能と創薬シンポジウム
    • Place of Presentation
      神戸学院大学(兵庫県)
    • Data Source
      KAKENHI-PROJECT-22500330
  • [Presentation] ミクログリア細胞に発現するIL-6の時計遺伝子による発現制御2012

    • Author(s)
      宝田剛志, 堀田彰悟, 棒葉繁紀, 米田幸雄
    • Organizer
      次世代を担う創薬・医療薬理シンポジウム
    • Place of Presentation
      神戸学院大学(兵庫県)
    • Year and Date
      2012-09-01
    • Data Source
      KAKENHI-PROJECT-22500330
  • [Presentation] ミクログリア細胞における時計遺伝子の機能解析2012

    • Author(s)
      宝田 剛志
    • Organizer
      生体機能と創薬シンポジウム2012
    • Place of Presentation
      神戸学院大学(兵庫県)
    • Data Source
      KAKENHI-PROJECT-22500330
  • [Presentation] アストロサイトのグルタミン酸輸送能に対するRunx2の調節機能2012

    • Author(s)
      宝田剛志、藤川晃一、米田幸雄
    • Organizer
      第85回日本薬理学会年会
    • Place of Presentation
      国立京都国際会館(京都府)
    • Data Source
      KAKENHI-PROJECT-22500330
  • [Presentation] NMDA receptor and uncoupling protein2012

    • Author(s)
      宝田剛志、福森良、米田幸雄
    • Organizer
      第22回日本臨床精神神経薬理学会・第42回日本神経精神薬理学会合同年会
    • Place of Presentation
      栃木県総合文化センター(栃木県)
    • Data Source
      KAKENHI-PROJECT-22500330
  • [Presentation] A role of the osteoblastic master regulator, runt-related factor 2 (Runx2), in astrocytes2012

    • Author(s)
      Takeshi Takarada
    • Organizer
      Joint Symposium of 11th Biennial Meeting of the Asia-Pacific Society for Neurochemistry and 55th Annual Meeting of the Japanese Society for Neurochemistry (APSN/JSN 2012), Invited Young Investigator Colloquia
    • Place of Presentation
      神戸国際会議場(兵庫県)
    • Year and Date
      2012-10-12
    • Data Source
      KAKENHI-PROJECT-22500330
  • [Presentation] アストロサイトのグルタミン酸輸送能に対するRunx2の調節機能2012

    • Author(s)
      宝田剛志
    • Organizer
      第85回日本薬理学会年会
    • Place of Presentation
      京都国際会館(京都)
    • Data Source
      KAKENHI-PROJECT-22500330
  • [Presentation] NMDA receptor and uncoupling protein2012

    • Author(s)
      宝田 剛志
    • Organizer
      第22回日本臨床精神神経薬理学会・第42回日本神経精神薬理学会合同年会
    • Place of Presentation
      栃木県総合文化センター(栃木県)
    • Invited
    • Data Source
      KAKENHI-PROJECT-22500330
  • [Presentation] 間葉系幹細胞に由来する各種細胞の機能制御に関する研究2011

    • Author(s)
      宝田剛志
    • Organizer
      日本薬学会北陸支部第123回例会
    • Place of Presentation
      金沢大学(金沢)
    • Year and Date
      2011-11-27
    • Data Source
      KAKENHI-PROJECT-22500330
  • [Presentation] スタディグループテーマ ~神経精神疾患の治療標的としてのアストロサイト~2011

    • Author(s)
      宝田剛志
    • Organizer
      第21回日本臨床精神神経薬理学会・第41回日本神経精神薬理学会合同年会
    • Place of Presentation
      京王プラザホテル(東京都)
    • Data Source
      KAKENHI-PROJECT-22500330
  • [Presentation] Possible regulation of adult neurogenesis by Myosin VI responsive to traumatic stress in murine hippocampus2011

    • Author(s)
      Takeshi Takarada, Yukio Yoneda
    • Organizer
      The 2nd Congress of Asian College of Neuropsychopharmacology (AsCNP)
    • Place of Presentation
      Grand Hilton Hotel (Korea)
    • Data Source
      KAKENHI-PROJECT-22500330
  • [Presentation] スタディグループテーマ~神経精神疾患の治療標的としてのアストロサイト~2011

    • Author(s)
      宝田剛志
    • Organizer
      第21回日本臨床精神神経薬理学会・第41回日本神経精神薬理学会合同年会
    • Place of Presentation
      東王プラザホテル(東京)
    • Data Source
      KAKENHI-PROJECT-22500330
  • [Presentation] Regulation of glutamate transport by runt related transcription factor-2 in astrocytes2011

    • Author(s)
      Takeshi Takarada, Koichi Fujikawa, Yukio Yoneda
    • Organizer
      Society for Neuroscience
    • Place of Presentation
      Walter E. Washington Convention Center(USA)
    • Year and Date
      2011-12-06
    • Data Source
      KAKENHI-PROJECT-22500330
  • [Presentation] 骨細胞由来因子Growth differentiation factor 15による破骨細胞活性制御2011

    • Author(s)
      檜井栄一、中谷絵莉、宝田剛志、米田幸雄
    • Organizer
      第84回日本薬理学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川県)
    • Year and Date
      2011-03-22
    • Data Source
      KAKENHI-PROJECT-22659065
  • [Presentation] 神経前駆細胞の新規分化能決定因子とその虚血応答性2011

    • Author(s)
      宝田剛志
    • Organizer
      第21回日本臨床精神神経薬理学会・第41回日本神経精神薬理学会合同年会
    • Place of Presentation
      京王プラザホテル(東京)(招待講演)
    • Data Source
      KAKENHI-PROJECT-22500330
  • [Presentation] Modulation by Ifrd1 of neuronal differentiation in neural progenitors2011

    • Author(s)
      宝田剛志
    • Organizer
      日本分子生物学会第11回春季シンポジウム金沢国際がん生物シンポジウム
    • Place of Presentation
      石川県立音楽堂(金沢)
    • Data Source
      KAKENHI-PROJECT-22500330
  • [Presentation] 時計遺伝子と骨組織2010

    • Author(s)
      宝田剛志
    • Organizer
      金沢大学薬学シンポジウム2010
    • Place of Presentation
      金沢大学(石川県)(招待講演)
    • Year and Date
      2010-12-02
    • Data Source
      KAKENHI-PROJECT-22500330
  • [Presentation] アストロサイトに発現するRunx2の機能解析2010

    • Author(s)
      宝田剛志、米田幸雄
    • Organizer
      第24回放射性同位元素研究連絡会
    • Place of Presentation
      金沢大学(石川県)
    • Year and Date
      2010-03-10
    • Data Source
      KAKENHI-PROJECT-20790250
  • [Presentation] 脳虚血応答性遺伝子Ifrd1の神経新生抑制作用2010

    • Author(s)
      宝田剛志,小西志歩,米田幸雄
    • Organizer
      十全医学会学術集会
    • Place of Presentation
      金沢大学(石川県)(招待講演
    • Year and Date
      2010-07-09
    • Data Source
      KAKENHI-PROJECT-22500330
  • [Presentation] 神経幹細胞とPTSD分子病態2010

    • Author(s)
      宝田剛志, 伊藤佑真, 米田幸雄
    • Organizer
      第83回日本薬理学会年会
    • Place of Presentation
      大阪国際会議場(大阪)
    • Year and Date
      2010-06-17
    • Data Source
      KAKENHI-PROJECT-20790250
  • [Presentation] 神経幹細胞とPTSD分子病態2010

    • Author(s)
      宝田剛志, 伊藤佑真, 米田幸雄
    • Organizer
      第83回日本薬理学会年会
    • Place of Presentation
      大阪国際会議場(大阪府)
    • Data Source
      KAKENHI-PROJECT-20790250
  • [Presentation] Runx2によるアストロサイトグルタミン酸トランスポーター制御2010

    • Author(s)
      宝田剛志、宝田美佳、米田幸雄
    • Organizer
      第118回日本薬理学会近畿部会
    • Place of Presentation
      千里ライフサイエンスセンター(大阪府)
    • Year and Date
      2010-11-14
    • Data Source
      KAKENHI-PROJECT-22500330
  • [Presentation] A Role of the Osteoblastic Master Regulator, Runt-related Factor 2(Runx 2), in Glutamate Transport in Astrocytes2010

    • Author(s)
      Takeshi Takarada, Ryota Nakazato, Yukio Yoneda
    • Organizer
      第29回内藤コンファレンス
    • Place of Presentation
      湘南国際村センター(神奈川県)
    • Data Source
      KAKENHI-PROJECT-22500330
  • [Presentation] 軟骨細胞に発現する時計遺伝子によるIndian hedgehog の発現制御2010

    • Author(s)
      宝田剛志、児玉歩美、檜井栄一、榛葉繁紀、米田幸雄
    • Organizer
      第17回日本時間生物学会
    • Place of Presentation
      早稲田大学(東京都)
    • Data Source
      KAKENHI-PROJECT-22500330
  • [Presentation] A Role of the Osteoblastic Master Regulator, Runt-related Factor 2(Runx 2) in Glutamate Transport in Astrocytes2010

    • Author(s)
      Takeshi Takarada, Ryota Nakazato, Yukio Yoneda
    • Organizer
      第29回内藤コンファレンス
    • Place of Presentation
      湘南国際村センター(神奈川県)
    • Data Source
      KAKENHI-PROJECT-22500330
  • [Presentation] 脳虚血応答性遺伝子Ifrd1の機能解析2010

    • Author(s)
      宝田剛志, 小西志歩, 米田幸雄
    • Organizer
      第130回日本薬学会年会
    • Place of Presentation
      就実大学(岡山県)
    • Data Source
      KAKENHI-PROJECT-20790250
  • [Presentation] 新規因子Ifrd1 による神経系前駆細胞の分化制御2010

    • Author(s)
      宝田剛志 ,小西志歩, 米田幸雄
    • Organizer
      Neuro2010
    • Place of Presentation
      神戸コンベンションセンター(兵庫県)
    • Data Source
      KAKENHI-PROJECT-22500330
  • [Presentation] 軟骨細胞に発現する時計遺伝子によるIndian hedgehogの発現制御2010

    • Author(s)
      宝田剛志、児玉歩美、檜井栄一、榛葉繁紀、米田幸雄
    • Organizer
      第17回日本時間生物学会
    • Place of Presentation
      早稲田大学(東京都)
    • Data Source
      KAKENHI-PROJECT-22500330
  • [Presentation] 新規因子Ifrd1による神経系前駆細胞の分化制御2010

    • Author(s)
      宝田剛志, 小西志歩, 米田幸雄
    • Organizer
      Neuro2010
    • Place of Presentation
      神戸コンベンションセンター(兵庫県)
    • Data Source
      KAKENHI-PROJECT-22500330
  • [Presentation] 脳虚血応答性遺伝子Ifrd1の機能解析2010

    • Author(s)
      宝田剛志, 小西志歩, 米田幸雄
    • Organizer
      第130回日本薬学会年会
    • Place of Presentation
      就実大学(岡山)
    • Year and Date
      2010-03-28
    • Data Source
      KAKENHI-PROJECT-20790250
  • [Presentation] アストロサイトに発現するRunx2の機能解析2010

    • Author(s)
      宝田剛志、米田幸雄
    • Organizer
      第24回放射性同位元素研究連絡会
    • Place of Presentation
      金沢大学(石川)
    • Year and Date
      2010-03-10
    • Data Source
      KAKENHI-PROJECT-20790250
  • [Presentation] HEK293細胞における機能的NMDA受容体の強制発現2009

    • Author(s)
      福森良, 谷浦秀夫, 中道範隆, 宝田剛志, 米田幸雄
    • Organizer
      日本薬学会第129年会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-20790250
  • [Presentation] Clock genes expressed in cultured microglia.2009

    • Author(s)
      Yamamoto, T., Takarada, T., Kodama, A., Tachibana, M., Yoneda, Y.
    • Organizer
      The 22nd Biennial Meeting of the ISN/APSN Joint Meeting
    • Place of Presentation
      BEXCO(Korea)
    • Data Source
      KAKENHI-PROJECT-20790250
  • [Presentation] Bone-related genes expressed in brain.2009

    • Author(s)
      Takarada, T., Yoneda, Y.
    • Organizer
      The 22nd Biennial Meeting of the ISN/APSN Joint Meeting
    • Place of Presentation
      BEXCO (Busan, Korea)
    • Data Source
      KAKENHI-PROJECT-20790250
  • [Presentation] Clock Genes Expressed by Microglial Cells.2009

    • Author(s)
      Tomomi Yamamoto, Takeshi Takarada, Ayumi Kodama, Masaki Tachibana, Yukio Yoneda
    • Organizer
      第19回日本臨床精神神経薬理学会・第39回日本神経精神薬理学会合同年会
    • Place of Presentation
      国立京都国際会館(京都)
    • Data Source
      KAKENHI-PROJECT-20790250
  • [Presentation] アストロサイトにおけるRunt related factor-2の機能的発現2009

    • Author(s)
      宝田剛志, 家亦美佳, 橘正毅, 米田幸雄
    • Organizer
      第52回日本神経化学会大会
    • Place of Presentation
      伊香保温泉ホテル天坊(群馬)
    • Data Source
      KAKENHI-PROJECT-20790250
  • [Presentation] GABARによる骨芽細胞の成熟調節2009

    • Author(s)
      高畑佳史, 宝田剛志, 宇野恭介, 藤森さゆ美, 檜井栄一, 米田幸雄
    • Organizer
      第82回日本薬理学会年会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-20790250
  • [Presentation] ミクログリア細胞における時計遺伝子の機能的発現2009

    • Author(s)
      山本朋未, 宝田剛志, 米田幸雄
    • Organizer
      第52回日本神経化学会大会
    • Place of Presentation
      伊香保温泉ホテル天坊(群馬)
    • Data Source
      KAKENHI-PROJECT-20790250
  • [Presentation] シスチン/グルタミン酸アンチポーター安定発現骨芽細胞株の樹立2009

    • Author(s)
      宇野恭介, 宝田剛志, 浜道啓太, 米田幸雄
    • Organizer
      第82回日本薬理学会年会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-20790250
  • [Presentation] 時計遺伝子による軟骨細胞成熟過程の制御2009

    • Author(s)
      児玉歩美, 宝田剛志, 檜井栄一, 米田 幸雄
    • Organizer
      第116回日本薬理学会近畿部会
    • Place of Presentation
      ピアザ淡海(滋賀)
    • Year and Date
      2009-11-13
    • Data Source
      KAKENHI-PROJECT-20790250
  • [Presentation] Expression of Runt Related Factor-2 by Astrocytes.2009

    • Author(s)
      Takeshi Takarada, Mika Takarada, Masaki Tachibana, Yukio Yoneda
    • Organizer
      第19回 日本臨床精神神経薬理学会・第39回 日本神経精神薬理学会 合同年会
    • Place of Presentation
      国立京都国際会館(京都府)
    • Data Source
      KAKENHI-PROJECT-20790250
  • [Presentation] Bone-related genes expressed in brain.2009

    • Author(s)
      Takeshi Takarada, Yukio Yoneda
    • Organizer
      The 22nd Biennial Meeting of the ISN/APSN Joint Meeting
    • Place of Presentation
      BEXCO(Korea)
    • Data Source
      KAKENHI-PROJECT-20790250
  • [Presentation] Expressiom of Runt Related Factor-2 by Astrocytes2009

    • Author(s)
      Takeshi Takarada, Mika Takarada, Masaki Tachibana, Yukio Yoneda
    • Organizer
      第19回日本臨床精神神経薬理学会・第39回日本神経精神薬理学会合同年会
    • Place of Presentation
      国立京都国際会館(京都)
    • Data Source
      KAKENHI-PROJECT-20790250
  • [Presentation] 脂肪細胞に発現するGABAシグナル分子2009

    • Author(s)
      中村由香里, 宝田剛志, 米田幸雄
    • Organizer
      日本薬学会第129年会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-20790250
  • [Presentation] アストロサイトにおけるRunt related factor-2の機能的発現2009

    • Author(s)
      宝田剛志, 家亦美佳, 橘正毅, 米田幸雄
    • Organizer
      第52回日本神経化学会大会
    • Place of Presentation
      伊香保温泉(群馬県)
    • Data Source
      KAKENHI-PROJECT-20790250
  • [Presentation] Runt related factor-2発現の脳内局在性2009

    • Author(s)
      橘正毅, 宝田剛志, 米田幸雄
    • Organizer
      日本薬学会第129年会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-20790250
  • [Presentation] 時計遺伝子Per1による軟骨細胞成熟調節2009

    • Author(s)
      児玉歩美, 宝田剛志, 佐原甲一, 檜井栄一, 米田幸雄
    • Organizer
      日本薬学会第129年会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-20790250
  • [Presentation] マウス中大脳動脈結紮モデルの作製2009

    • Author(s)
      小西志歩, 宝田剛志, 中道範隆, 黒川晋太郎, 米田幸雄
    • Organizer
      日本薬学会第129年会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-20790250
  • [Presentation] Runx2プロモーターを安定発現する骨芽細胞株MC3T3-E1細胞の樹立2009

    • Author(s)
      浜道啓太, 宇野恭介, 檜井栄一, 宝田剛志, 米田幸雄
    • Organizer
      日本薬学会第129年会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-20790250
  • [Presentation] 骨細胞株MLO-Y4細胞の機能解析2009

    • Author(s)
      中谷絵莉, 家亦美佳, 中島紘子, 宝田剛志, 米田幸雄
    • Organizer
      日本薬学会第129年会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-20790250
  • [Presentation] 細胞内グルタチオン濃度制御を介するグルタミン酸による間葉系幹細胞の分化調整2009

    • Author(s)
      家亦美佳, 宝田剛志, 米田幸雄
    • Organizer
      第82回日本薬理学会年会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-20790250
  • [Presentation] 時計遺伝子Per1による軟骨細胞成熟調節2009

    • Author(s)
      テル天坊(群馬) [11]児玉歩美, 宝田剛志, 佐原甲一, 檜井 栄一, 米田幸雄
    • Organizer
      日本薬学会第129年会
    • Place of Presentation
      国立京都国際会館(京都)
    • Data Source
      KAKENHI-PROJECT-20790250
  • [Presentation] Runt related factor-2のアストロサイトにおける機能的発現2009

    • Author(s)
      宝田剛志, 米田幸雄
    • Organizer
      第82回日本薬理学会年会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-20790250
  • [Presentation] 時計遺伝子による軟骨細胞株ATDC5細胞の分化制御2008

    • Author(s)
      佐原甲一, 宝田剛志, 檜井栄一, 米田幸雄
    • Organizer
      第113回日本薬理学会近畿部会
    • Place of Presentation
      岡山
    • Year and Date
      2008-06-20
    • Data Source
      KAKENHI-PROJECT-20790250
  • [Presentation] GABAシグナルによる神経系前駆細胞の増殖と分化の調節2008

    • Author(s)
      小澤秀介, 福井正樹, 宝田剛志, 谷浦秀夫, 中道範隆, 米田幸雄
    • Organizer
      第51回日本神経化学会大会
    • Place of Presentation
      富山
    • Data Source
      KAKENHI-PROJECT-20790250
  • [Presentation] 軟骨細胞分化における時計遺伝子Period1の役割2008

    • Author(s)
      児玉歩美, 佐原甲一, 宝田剛志, 米田幸雄
    • Organizer
      生体機能と創薬シンポジウム2008
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-20790250
  • [Presentation] 骨関連遺伝子の脳内における発現2008

    • Author(s)
      宝田剛志, 黒川晋太郎, 砺波, 佑介, 小西志歩, 米田幸雄
    • Organizer
      第51回日本神経化学会大会
    • Place of Presentation
      富山
    • Data Source
      KAKENHI-PROJECT-20790250
  • [Presentation] グルタミン酸神経毒性に対する田七人参含有成分notoginsenosideR1の保護効果2008

    • Author(s)
      顧彬, 中村有加里, 神戸悠輝, 田熊一散, 山田清文, 張文生, 宝田剛志, 中道範隆, 米田幸雄
    • Organizer
      生体機能と創薬シンポジウム2008
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-20790250
  • [Presentation] 中大脳動脈決紮に伴う脳内グルタメイトレセプターの発現変化2008

    • Author(s)
      黒川晋太郎, 原智也, 小西志歩, 宝田剛志, 中道範隆, 米田幸雄
    • Organizer
      第51回日本神経化学会大会
    • Place of Presentation
      富山
    • Data Source
      KAKENHI-PROJECT-20790250
  • [Presentation] ミクログリア細胞に発現する時計遺伝子2008

    • Author(s)
      山本朋未, 宝田剛志, 佐原甲一, 小椋 正人, 谷浦秀夫, 米田幸雄
    • Organizer
      第18回日本臨床精神神経薬理学会・第38回日本神経精神薬理学会合同年会
    • Place of Presentation
      品川プリンスホテル(東京)
    • Data Source
      KAKENHI-PROJECT-20790250
  • [Presentation] マウス脳海馬におけるPTSD応答性ミオシンVIの発現2008

    • Author(s)
      橘正毅, 玉置啓祐, 伊東佑真, 宝田剛志, 谷浦秀夫, 中道範隆, 米田幸雄
    • Organizer
      第51回日本神経化学会大会
    • Place of Presentation
      富山
    • Data Source
      KAKENHI-PROJECT-20790250
  • [Presentation] 軟骨細胞に発現するIndian hedgehogの時計遺伝子による調節機構2008

    • Author(s)
      宝田剛志, 佐原甲一, 米田幸雄
    • Organizer
      第26回日本骨代謝学会学術集会
    • Place of Presentation
      大阪国際会議場(大阪)
    • Data Source
      KAKENHI-PROJECT-20790250
  • [Presentation] 脳内における骨関節系遺伝子の発現2008

    • Author(s)
      宝田剛志, 米田幸雄
    • Organizer
      第114回日本薬理学会近畿部会
    • Place of Presentation
      神戸
    • Year and Date
      2008-11-14
    • Data Source
      KAKENHI-PROJECT-20790250
  • [Presentation] 軟骨細胞に発現するIndian hedgehogの時計遺伝子による調節機構2008

    • Author(s)
      宝田剛志, 佐原甲一, 米田幸雄
    • Organizer
      第26回日本骨代謝学会学術集会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-20790250
  • [Presentation] 脳における骨関節系遺伝子の発現2008

    • Author(s)
      小西志歩, 宝田剛志, 黒川晋太郎, 米田幸雄
    • Organizer
      第18回日本臨床精神神経薬理学会・第38回日本神経精神薬理学会合同年会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-20790250
  • [Presentation] 軟骨細胞分化における時計遺伝子Period1の役割2008

    • Author(s)
      児玉歩美, 佐原甲一, 宝田剛志, 米田 幸雄
    • Organizer
      生体機能と創薬シンポジウム
    • Place of Presentation
      星薬科大学(東京)
    • Data Source
      KAKENHI-PROJECT-20790250
  • [Presentation] シスチン/グルタミン酸アンチポーターによる骨芽細胞の増殖制御2008

    • Author(s)
      宇野恭介, 宝田剛志, 浜道啓太, 米田幸雄
    • Organizer
      第26回日本骨代謝学会学術集会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-20790250
  • [Presentation] 間葉系幹細胞に発現するアドレナリン受容体の機能2008

    • Author(s)
      高畑佳史, 家亦美佳, 宝田剛志, 米田幸雄
    • Organizer
      第113回日本薬理学会近畿部会
    • Place of Presentation
      岡山
    • Year and Date
      2008-06-20
    • Data Source
      KAKENHI-PROJECT-20790250
  • [Presentation] GABABR1サブユニット安定発現骨芽細胞株の機能解析2008

    • Author(s)
      高畑佳史, 宝田剛志, 宇野恭介, 藤森さゆ美, 檜井栄一, 米田幸雄
    • Organizer
      第114回日本薬理学会近畿部会
    • Place of Presentation
      神戸
    • Year and Date
      2008-11-14
    • Data Source
      KAKENHI-PROJECT-20790250
  • [Presentation] 間葉系幹細胞に発現するアドレナリン受容体の機能2008

    • Author(s)
      高畑佳史, 宝田剛志, 家亦美佳, 山本朋未, 宇野恭介, 米田幸雄
    • Organizer
      第26回日本骨代謝学会学術集会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-20790250
  • [Presentation] ミクログリア細胞に発現する時計遺伝子群2008

    • Author(s)
      山本朋未, 宝田剛志, 佐原甲一, 橘正毅, 谷浦秀夫, 米田幸雄
    • Organizer
      第51回日本神経化学会大会
    • Place of Presentation
      第51回日本神経化学会大会(富山)
    • Data Source
      KAKENHI-PROJECT-20790250
  • [Presentation] ミクログリア細胞に発現する時計遺伝子2008

    • Author(s)
      山本朋未, 宝田剛志, 佐原甲一, 小椋正人, 谷浦秀夫, 米田幸雄
    • Organizer
      第18回日本臨床精神神経薬理学会・第38回日本神経精神薬理学会合同年会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-20790250
  • [Presentation] ミクログリア細胞における時計遺伝子の発現2008

    • Author(s)
      山本朋未, 宝田剛志, 佐原甲一, 小椋正人, 谷浦秀夫, 米田幸雄
    • Organizer
      第113回日本薬理学会近畿部会
    • Place of Presentation
      岡山
    • Year and Date
      2008-06-20
    • Data Source
      KAKENHI-PROJECT-20790250
  • [Presentation] 時計遺伝子による軟骨細胞株ATDC5細胞の分化制御2008

    • Author(s)
      佐原甲一, 宝田剛志, 檜井栄一, 米田 幸雄
    • Organizer
      第113回日本薬理学会近畿部会
    • Place of Presentation
      ホテルグランヴィア岡山(岡山)
    • Year and Date
      2008-06-20
    • Data Source
      KAKENHI-PROJECT-20790250
  • [Presentation] ミクログリア細胞に発現する時計遺伝子群2008

    • Author(s)
      山本朋未, 宝田剛志, 佐原甲一, 橘正毅, 谷浦秀夫, 米田幸雄
    • Organizer
      第51回日本神経化学会大会
    • Place of Presentation
      富山
    • Data Source
      KAKENHI-PROJECT-20790250
  • [Presentation] グルタミン酸による細胞内グルタチオン濃度調節を介する骨芽細胞分化抑制2008

    • Author(s)
      家亦美佳, 宝田剛志, 米田幸雄
    • Organizer
      第26回日本骨代謝学会学術集会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-20790250
  • [Presentation] ミクログリア細胞における時計遺伝子の発現2008

    • Author(s)
      テルグランヴィア岡山(岡山) [17]山本朋未, 宝田剛志, 佐原甲一, 小椋 正人, 谷浦秀夫, 米田幸雄
    • Organizer
      第113回日本薬理学会近畿部会
    • Place of Presentation
      ホテルグランヴィア岡山(岡山)
    • Year and Date
      2008-06-20
    • Data Source
      KAKENHI-PROJECT-20790250
  • [Presentation] 神経細胞毒性におけるグルタミントランスポーターSlc38a1の役割

    • Author(s)
      宝田 剛志、中里 亮太、中村 早希、藤川 晃一、高 巳奇、檜井 栄一、米田 幸雄
    • Organizer
      第88回日本薬理学会年会
    • Place of Presentation
      名古屋
    • Year and Date
      2015-03-18 – 2015-03-20
    • Data Source
      KAKENHI-PROJECT-26460387
  • [Presentation] A role of the osteoblastic master regulator, runt-related factor 2 (Runx2), in astrocytes.

    • Author(s)
      Takeshi Takarada
    • Organizer
      Joint Symposium of 11th Biennial Meeting of the Asia-Pacific Society for Neurochemistry and 55th Annual Meeting of the Japanese Society for Neurochemistry (APSN/JSN 2012)
    • Place of Presentation
      神戸国際会議場(兵庫県)
    • Invited
    • Data Source
      KAKENHI-PROJECT-22500330
  • [Presentation] 体内時計によるグリアネットワーク調節に注目した「精神-疼痛」連関メカニズムの解明

    • Author(s)
      宝田 剛志
    • Organizer
      「グリアアセンブリによる脳機能発現の制御と病態」第1回夏のワークショップ
    • Place of Presentation
      京都
    • Year and Date
      2014-08-08 – 2014-08-09
    • Data Source
      KAKENHI-PUBLICLY-26117507
  • [Presentation] Skeletal phenotypes of Runx2 conditional knockout mice.

    • Author(s)
      Takeshi Takarada, Ryota Nakazato, Azusa Tsuchikane, Eiichi Hinoi, Yukio Yoneda
    • Organizer
      The 12th Annual Meeting of the International Society for Stem Cell Reserch (ISSCR)
    • Place of Presentation
      Vancouver, Canada
    • Year and Date
      2014-06-18 – 2014-06-21
    • Data Source
      KAKENHI-PROJECT-26460387
  • [Presentation] グルタミン酸トランスポーターの転写制御因子Runx2による調節機構

    • Author(s)
      宝田 剛志
    • Organizer
      第7回トランスポーター研究会年会/JTRA2012
    • Place of Presentation
      京都大学(京都府)
    • Invited
    • Data Source
      KAKENHI-PROJECT-22500330
  • [Presentation] 神経細胞毒性におけるグルタミントランスポーターSlc38a1の役割

    • Author(s)
      宝田 剛志、中里 亮太、中村 早希、藤川 晃一、高 巳奇、檜井 栄一、米田 幸雄
    • Organizer
      第88回日本薬理学会年会
    • Place of Presentation
      名古屋
    • Year and Date
      2015-03-18 – 2015-03-20
    • Data Source
      KAKENHI-PUBLICLY-26117507
  • [Presentation] ミクログリア細胞に発現するIL-6の時計遺伝子による発現制御

    • Author(s)
      宝田 剛志
    • Organizer
      次世代を担う創薬・医療薬理シンポジウム2012
    • Place of Presentation
      神戸学院大学(兵庫県)
    • Data Source
      KAKENHI-PROJECT-22500330
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    # of Collaborated Products: 0 results
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  • 79.  越智 広樹
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