Togashi Yosuke 冨樫庸介

Researcher Number	80758326
Other IDs
Affiliation (Current)	2023: 岡山大学, 医歯薬学域, 教授 2023: 千葉県がんセンター(研究所), がん治療開発グループ細胞治療開発研究部, 客員研究員
Affiliation (based on the past Project Information) *help	2023: 岡山大学, 医歯(薬)学総合研究科, 教授 2021 – 2023: 岡山大学, 医歯薬学域, 教授 2021 – 2022: 千葉県がんセンター(研究所), がん治療開発グループ細胞治療開発研究部, 客員研究員 2019 – 2020: 千葉県がんセンター(研究所), がん治療開発グループ細胞治療開発研究部, 部長代理 2016 – 2019: 国立研究開発法人国立がん研究センター, 先端医療開発センター, 研究員 2015: 近畿大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Medium-sized Section 50:Oncology and related fields / Gastroenterology / Immunology / Respiratory organ internal medicine / Basic Section 53030:Respiratory medicine-related / Medium-sized Section 53:Organ-based internal medicine and related fields Except Principal Investigator Basic Section 53050:Dermatology-related / Digestive surgery / Basic Section 55040:Respiratory surgery-related / Basic Section 53010:Gastroenterology-related … More / Broad Section I / Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields / Basic Section 56050:Otorhinolaryngology-related / Basic Section 59040:Nutrition science and health science-related / Basic Section 50010:Tumor biology-related Less
Keywords	Principal Investigator 腫瘍免疫 / ネオ抗原 / EGFR阻害剤 / 大腸癌 / 膵癌 / FGFRシグナル / PI3Kシグナル / FGF9 / AKT2 / MAP3K10 … More / がん免疫 / ゲノム異常 / 非小細胞肺癌 / 体細胞変異数 / EGFR遺伝子変異 / 胃癌 / 非小細胞肺がん / がん免疫編集 / PD-1 / がん抗原 / 肺癌 … More Except Principal Investigator がん微小環境 / がん関連線維芽細胞 / 免疫チェックポイント / 職業性胆管癌 / 化学発癌 / DNA傷害 / 多中心性発癌 / 癌免疫応答 / 免疫チェックポイント阻害剤 / 多中性発癌 / 慢性胆管傷害 / DNA損傷 / 肝内胆管癌 / 遺伝子変異 / 免疫学 / 非小細胞肺がん / 肝細胞癌 / 腫瘍抗原認識 / 腫瘍微小環境 / メラノーマ / TIL / 腫瘍特異的T細胞 / single cell RNA sequence / 悪性リンパ腫 / CRISPRスクリーニング / シングルセル解析 / 内在性レトロウイルス / 肺癌 / 腫瘍免疫応答 / 細胞接着 / 免疫疲弊 / 抗腫瘍活性 / 悪性黒色腫 / 腫瘍浸潤リンパ球 / 免疫チェックポイント阻害薬 / 重粒子線治療 / 腫瘍免疫 / 免疫ゲノム解析 / 細胞外小胞 / 癌 / マクロファージ / 転移ニッチ / エクソソーム / 線溶阻害因子 Less

Roles of cancer extracellular vesicles in hijacking macrophages and metastatic niche formation
- Principal Investigator
  
  江口傑徳
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Okayama University
Elucidation of Tumor Microenvironment Network Regulated by Fibrinolysis Inhibitory Factor and Its Therapeutic Application
- Principal Investigator
  
  伊達慶一
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Okayama University
腫瘍微小環境のゲノム異常とクローン性造血の関係解明Principal Investigator
- Principal Investigator
  
  冨樫庸介
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Fund for the Promotion of Joint International Research (International Collaborative Research)
- Review Section
  
  Medium-sized Section 53:Organ-based internal medicine and related fields
- Research Institution
  Okayama University
マトリセルラータンパク質阻害によるがん微小環境の破壊と抗腫瘍効果の検討
- Principal Investigator
  
  豊岡伸一
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Okayama University
Analysis of tumor antigen recognition of T cell accumulated in the underlying liver of hepatocellular carcinoma
- Principal Investigator
  
  小笠原定久
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Chiba University
免疫チェックポイント阻害剤の課題克服を目指した腫瘍特異的T細胞の解析
- Principal Investigator
  
  猪爪隆史
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53050:Dermatology-related
- Research Institution
  Chiba University
Spatiotemporal T-cell differentiation dynamics in the tumor "peripheral" environmentPrincipal Investigator
- Principal Investigator
  
  冨樫庸介
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 50:Oncology and related fields
- Research Institution
  Okayama University
Clarification of the mechanism for endogenous retrovirus to get involved in the antitumor immunity response
- Principal Investigator
  
  豊岡伸一
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  Okayama University
Comprehensive elucidation of molecular pathogenesis based on genetic abnormalities in malignant lymphoma
- Principal Investigator
  
  片岡圭亮
- Project Period (FY)
  2021 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Review Section
  
  Broad Section I
- Research Institution
  Keio University
悪性黒色腫の腫瘍特異的疲弊T細胞に発現する新規接着因子の機能解析と臨床応用
- Principal Investigator
  
  盛永敬郎
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53050:Dermatology-related
- Research Institution
  Chiba Cancer Center (Research Institute)
鼻副鼻腔原発の粘膜型悪性黒色腫の免疫ゲノム解析および重粒子線の影響解明
- Principal Investigator
  
  花澤豊行
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Chiba University
Analysis of PD-1+ tumor-infiltrating T cells according to cancer antigen hierarchyPrincipal Investigator
- Principal Investigator
  
  冨樫庸介
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Okayama University
  Chiba Cancer Center (Research Institute)
Novel immunoediting mechanisms via somatic mutationsPrincipal Investigator
- Principal Investigator
  
  Togashi Yosuke
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 50:Oncology and related fields
- Research Institution
  Chiba Cancer Center (Research Institute)
Studies of treatment and carcinogenesis for intrahepatic cholangiocarcinoma by genomic and immunological analysis
- Principal Investigator
  
  Kubo Shoji
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Osaka City University
Gene alterations and anti-tumor immunityPrincipal Investigator
- Principal Investigator
  
  Togashi Yosuke
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Immunology
  Respiratory organ internal medicine
- Research Institution
  National Cancer Center Japan
Novel biomarkers for EGFR inhibitors in gastroenterological cancers based on CGH analysesPrincipal Investigator
- Principal Investigator
  
  Togashi Yosuke
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Gastroenterology
- Research Institution
  National Cancer Center Japan
  Kinki University

All 2022 2021 2020 2019 2018 2017 2016 2015

All Journal Article Presentation Book Patent

[Book] がん免疫ペディア2022
- Author(s)
  川瀬勝隆、冨樫庸介
- Total Pages
  2
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-20H03694
[Book] 実験医学増刊（シングルセルゲノミクスで見える新しい生命象）2019
- Author(s)
  鈴木穣、渡辺亮（分担執筆：冨樫庸介）
- Total Pages
  6
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-19K22574
[Book] 実験医学増刊（がん免疫療法の個別化を支える最新・腫瘍免疫学）2019
- Author(s)
  河上裕（分担執筆：冨樫庸介）
- Total Pages
  8
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-19K22574
[Journal Article] Programmed Death-Ligand 1-Rich Premetastatic Niche in Adjuvant Chemotherapy2022
- Author(s)
  Yamamoto Hiromasa、Togashi Yosuke
- Journal Title
  
  Journal of Thoracic Oncology
  
  Volume: 17 Issue: 1 Pages: 10-12
- DOI
  10.1016/j.jtho.2021.10.019
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03694
[Journal Article] HLA Class I Analysis Provides Insight Into the Genetic and Epigenetic Background of Immune Evasion in Colorectal Cancer With High Microsatellite Instability2022
- Author(s)
  Kawazu M, Ueno T, Saeki K, Sax N, Togashi Y, Kanaseki T, Chida K, Kishigami F, Sato K, Kojima S, Tanegashima T, Matsubara D, Tane K, Tanaka Y, Iinuma H, Hashiguchi Y, Hazama S, Khor SS, Tokunaga K, Tsuboi M, Niki T, Eto M, Shitara K, Torigoe T, Ishihara S, Aburatani H, Haeno H, Nishikawa H, Mano H
- Journal Title
  
  Gastroenterology
  
  Volume: 162 Issue: 3 Pages: 799-812
- DOI
  10.1053/j.gastro.2021.10.010
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H06162, KAKENHI-PROJECT-20H03694, KAKENHI-PROJECT-21H02772, KAKENHI-PROJECT-20K08531, KAKENHI-PROJECT-21K12117
[Journal Article] PD-1 blockade therapy promotes infiltration of tumor-attacking exhausted T cell clonotypes2022
- Author(s)
  Nagasaki Joji、Inozume Takashi、Yosuke Togashi et al.
- Journal Title
  
  Cell Reports
  
  Volume: 38 Issue: 5 Pages: 110331-110331
- DOI
  10.1016/j.celrep.2022.110331
- NAID
  120007192058
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08744, KAKENHI-PROJECT-17H06162, KAKENHI-PROJECT-20H03694, KAKENHI-PROJECT-21H02772, KAKENHI-PROJECT-21K07112, KAKENHI-PROJECT-21K08152, KAKENHI-PROJECT-21K08314, KAKENHI-PROJECT-21K09625, KAKENHI-PROJECT-21K12117
[Journal Article] Lactic acid promotes PD-1 expression in regulatory T cells in highly glycolytic tumor microenvironments2022
- Author(s)
  Kumagai S, Koyama S, Itahashi K, Tanegashima T, Lin YT, Togashi Y, Kamada T, Irie T, Okumura G, Kono H, Ito D, Fujii R, Watanabe S, Sai A, Aokage K, Suzuki J, Ishii G, Kuwata T, Sakamoto N, Kawazu M, Ueno T, Mori T, Yamazaki N, Tsuboi M, Yatabe Y, Kinoshita T, Doi T, Shitara K, Mano H, Nishikawa H
- Journal Title
  
  Cancer Cell
  
  Volume: 40 Issue: 2 Pages: 201-218
- DOI
  10.1016/j.ccell.2022.01.001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H06162, KAKENHI-PROJECT-20H03461, KAKENHI-PROJECT-20H03694, KAKENHI-PROJECT-20H04519, KAKENHI-PROJECT-21H02772, KAKENHI-PROJECT-20K07383, KAKENHI-PROJECT-20K08531, KAKENHI-PROJECT-21K07112, KAKENHI-PROJECT-21K07252, KAKENHI-PROJECT-21K12117, KAKENHI-PROJECT-16H06279, KAKENHI-PROJECT-22KJ3156
[Journal Article] Preoperative Chemoradiotherapy Plus Nivolumab Before Surgery in Microsatellite Stable and Microsatellite Instability-High Locally Advanced Rectal Cancer Patients2022
- Author(s)
  Bando H, Tsukada Y, Inamori K, Togashi Y, Koyama S, Kotani D, Fukuoka S, Yuki S, Komatsu Y, Homma S, Taketomi A, Uemura M, Kato T, Fukui M, Wakabayashi M, Nakamura N, Kojima M, Kawachi H, Kirsch R, Yoshida T, Suzuki Y, Sato A, Nishikawa H, Ito M, Yoshino T
- Journal Title
  
  Clinical Cancer Research
  
  Volume: 28 Issue: 6 Pages: 1136-1146
- DOI
  10.1158/1078-0432.ccr-21-3213
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H06162, KAKENHI-PROJECT-20H03694, KAKENHI-PROJECT-20K09056
[Journal Article] Aging, cancer, and antitumor immunity2021
- Author(s)
  Ikeda Hideki、Togashi Yosuke
- Journal Title
  
  International Journal of Clinical Oncology
  
  Volume: Epub Issue: 2 Pages: 316-322
- DOI
  10.1007/s10147-021-01913-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03694, KAKENHI-PROJECT-19K22574
[Journal Article] Transcript-targeted analysis reveals isoform alterations and double-hop fusions in breast cancer2021
- Author(s)
  Namba Shinichi、Ueno Toshihide、Kojima Shinya、Kobayashi Kenya、Kawase Katsushige、Tanaka Yosuke、Inoue Satoshi、Kishigami Fumishi、Kawashima Shusuke、Maeda Noriko、Ogawa Tomoko、Hazama Shoichi、Togashi Yosuke、Ando Mizuo、Shiraishi Yuichi、Mano Hiroyuki、Kawazu Masahito
- Journal Title
  
  Communications Biology
  
  Volume: 4 Issue: 1 Pages: 1320-1320
- DOI
  10.1038/s42003-021-02833-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03694, KAKENHI-PROJECT-21H02772, KAKENHI-PROJECT-21K08711, KAKENHI-PROJECT-21K12117
[Journal Article] Vaginal Transmission of Cancer from Mothers with Cervical Cancer to Infants2021
- Author(s)
  Arakawa A, Ichikawa H, Kubo T, Motoi N, Kumamoto T, Nakajima M, Yonemori K, Noguchi E, Sunami K, Shiraishi K, Kakishima H, Yoshida H, Hishiki T, Kawakubo N, Kuroda T, Kiyokawa T, Yamada K, Yanaihara N, et al, and Kohno T, Ogawa C.
- Journal Title
  
  New England Journal of Medicine
  
  Volume: 384 Issue: 1 Pages: 42-50
- DOI
  10.1056/nejmoa2030391
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07036, KAKENHI-PROJECT-17H01592, KAKENHI-PROJECT-20H00545, KAKENHI-PROJECT-20H03694, KAKENHI-PROJECT-19K22574, KAKENHI-PROJECT-17H06162, KAKENHI-PROJECT-20H03695
[Journal Article] Highly immunogenic cancer cells require activation of the WNT pathway for immunological escape2021
- Author(s)
  Takeuchi Y, Tanegashima T, Sato E, Irie T, Sai A, Itahashi K, Kumagai S, Tada Y, Togashi Y, Koyama S, Akbay EA, Karasaki T, Kataoka K, Funaki S, Shintani Y, Nagatomo I, Kida H, Ishii G, Miyoshi T, Aokage K, Kakimi K, Ogawa S, Okumura M, Eto M, Kumanogoh A, Tsuboi M, Nishikawa H
- Journal Title
  
  Science Immunology
  
  Volume: 6 Issue: 65
- DOI
  10.1126/sciimmunol.abc6424
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H06162, KAKENHI-PROJECT-19H05656, KAKENHI-PROJECT-20H03694, KAKENHI-PROJECT-21K07112
[Journal Article] Single-Cell Analysis of the Multicellular Ecosystem in Viral Carcinogenesis by HTLV-12021
- Author(s)
  Koya J, Saito Y, Kameda T, Kogure Y, Yuasa M, Nagasaki J, McClure MB, Shingaki S, Tabata M, Tahira Y, Akizuki K, Kamiunten A, Sekine M, Shide K, Kubuki Y, Hidaka T, Kitanaka A, Nakano N, Utsunomiya A, Togashi Y, Ogawa S, Shimoda K, Kataoka K
- Journal Title
  
  Blood Cancer Discovery
  
  Volume: 2 Issue: 5 Pages: 450-467
- DOI
  10.1158/2643-3230.bcd-21-0044
- NAID
  120007145001
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07880, KAKENHI-PROJECT-19H05656, KAKENHI-PROJECT-20H03694, KAKENHI-PROJECT-20K08715, KAKENHI-PROJECT-22KJ0622
[Journal Article] HSP90 inhibition overcomes EGFR amplification-induced resistance to third-generation EGFR-TKIs2021
- Author(s)
  Watanabe S, Goto Y, Yasuda H, Kohno T, Motoi N, Ohe Y, Nishikawa H, Kobayashi SS, Kuwano K, Togashi Y.
- Journal Title
  
  Thoracic Cancer
  
  Volume: 12 Issue: 5 Pages: 631-42
- DOI
  10.1111/1759-7714.13839
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07036, KAKENHI-PROJECT-20H03694, KAKENHI-PROJECT-19K22574, KAKENHI-PROJECT-16K21746, KAKENHI-PROJECT-17H06162
[Journal Article] TIGIT/CD155 axis mediates resistance to immunotherapy in patients with melanoma with the inflamed tumor microenvironment2021
- Author(s)
  Kawashima S, Inozume T, Kawazu M, Ueno T, Nagasaki J, Tanji E, Honobe A, Ohnuma T, Kawamura T, Umeda Y, Nakamura Y, Kawasaki T, Kiniwa Y, Yamasaki O, Fukushima S, Ikehara Y, Mano H, Suzuki Y, Nishikawa H, Matsue H, Togashi Y.
- Journal Title
  
  Journal for ImmunoTherapy of Cancer
  
  Volume: 9 Issue: 11 Pages: e003134-e003134
- DOI
  10.1136/jitc-2021-003134
- NAID
  120007175403
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07682, KAKENHI-PROJECT-19K08744, KAKENHI-PROJECT-17H06162, KAKENHI-PROJECT-19H05650, KAKENHI-PROJECT-20H03694, KAKENHI-PROJECT-21H02772, KAKENHI-PROJECT-20K08652, KAKENHI-PROJECT-21K06910, KAKENHI-PROJECT-21K08351, KAKENHI-PROJECT-21K12117
[Journal Article] Potentiality of multiple modalities for single-cell analyses to evaluate the tumor microenvironment in clinical specimens2021
- Author(s)
  Kashima Yukie、Togashi Yosuke、Fukuoka Shota、et al.
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 341-341
- DOI
  10.1038/s41598-020-79385-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03694, KAKENHI-PROJECT-19K22574, KAKENHI-PROJECT-17H06162
[Journal Article] Importance of lymph node immune responses in MSI-H/dMMR colorectal cancer2021
- Author(s)
  Inamori Koji、Togashi Yosuke、Fukuoka Shota、Akagi Kiwamu、Ogasawara Kouetsu、Irie Takuma、Motooka Daisuke、Kobayashi Yoichi、Sugiyama Daisuke、Kojima Motohiro、Shiiya Norihiko、Nakamura Shota、Maruyama Shoichi、Suzuki Yutaka、Ito Masaaki、Nishikawa Hiroyoshi
- Journal Title
  
  JCI Insight
  
  Volume: 8 Issue: 9 Pages: 137365-137365
- DOI
  10.1172/jci.insight.137365
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-16H06497, KAKENHI-PROJECT-19K22574, KAKENHI-PROJECT-17H06162, KAKENHI-PROJECT-20H03694
[Journal Article] Site-Specific and Targeted Therapy Based on Molecular Profiling by Next-Generation Sequencing for Cancer of Unknown Primary Site: A Nonrandomized Phase 2 Clinical Trial2020
- Author(s)
  Hayashi, H. Takiguchi, Y. Minami, H. Akiyoshi, K. Segawa, Y. Ueda, H. Iwamoto, Y. Kondoh, C. Matsumoto, K. Takahashi, S. Yasui, H. Sawa, T. Onozawa, Y. Chiba, Y. Togashi, Y. Fujita, Y. Sakai, K. Tomida, S. Nishio, K. Nakagawa, K.
- Journal Title
  
  JAMA Oncol
  
  Volume: 6 Issue: 12 Pages: 1931-1938
- DOI
  10.1001/jamaoncol.2020.4643
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08561, KAKENHI-PLANNED-17H06404, KAKENHI-PROJECT-20H03694, KAKENHI-PROJECT-20H03771, KAKENHI-PROJECT-19K22574
[Journal Article] Multicenter Phase I/II Trial of Napabucasin and Pembrolizumab in Patients with Metastatic Colorectal Cancer (EPOC1503/SCOOP Trial)2020
- Author(s)
  Kawazoe Akihito、Kuboki Yasutoshi、Shinozaki Eiji、Hara Hiroki、Nishina Tomohiro、Komatsu Yoshito、Yuki Satoshi、Wakabayashi Masashi、Nomura Shogo、Sato Akihiro、Kuwata Takeshi、Kawazu Masahito、Mano Hiroyuki、Togashi Yosuke、Nishikawa Hiroyoshi、Yoshino Takayuki
- Journal Title
  
  Clinical Cancer Research
  
  Volume: 26 Issue: 22 Pages: 5887-5894
- DOI
  10.1158/1078-0432.ccr-20-1803
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03694, KAKENHI-PROJECT-18K07320, KAKENHI-PROJECT-19K22574, KAKENHI-PROJECT-17H06162
[Journal Article] Enhanced Tumor Response to Radiotherapy After PD-1 Blockade in Metastatic Gastric Cancer2020
- Author(s)
  Sasaki A, Nakamura Y, Togashi Y, Kuno H, Hojo H, Kageyama S, Nakamura N, Takashima K, Kadota T, Yoda Y, Mishima S, Sawada K, Kotani D, Kawazoe A, Kuboki Y, Taniguchi H, Kojima T, Doi T, Yoshino T, Yano T, Kobayashi T, Akimoto T, Nishikawa H, Shitara K.
- Journal Title
  
  Gastric Cancer
  
  Volume: - Issue: 5 Pages: 893-903
- DOI
  10.1007/s10120-020-01058-4
- NAID
  40022329655
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22574, KAKENHI-PROJECT-19K08190, KAKENHI-PROJECT-20H03694
[Journal Article] The potential application of PD-1 blockade therapy for early-stage biliary tract cancer.2020
- Author(s)
  Umemoto K, Togashi Y, Arai Y, Nakamura H, Takahashi S, Tanegashima T, Kato M, Nishikawa T, Sugiyama D, Kojima M, Gotohda N, Kuwata T, Ikeda M, Shibata T, Nishikawa H.
- Journal Title
  
  Int Immunol.
  
  Volume: 32 Issue: 4 Pages: 273-281
- DOI
  10.1093/intimm/dxz080
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07035, KAKENHI-PROJECT-20H03694, KAKENHI-PROJECT-18K07956, KAKENHI-PROJECT-19K22574, KAKENHI-PROJECT-17H06162
[Journal Article] TENERGY: Multicenter Phase II Study of Atezolizumab Monotherapy Following Definitive Chemoradiotherapy With 5-FU Plus Cisplatin in Patients With Unresectable Locally Advanced Esophageal Squamous Cell Carcinoma2020
- Author(s)
  Bando H, Kotani D, Tsushima T, Hara H, Kadowaki S, Kato K, Chin K, Yamaguchi K, Kageyama SI, Hojo H, Nakamura M, Tachibana H, Wakabayashi M, Fukutani M, Togashi Y, Fuse N, Nishikawa H, Kojima T.
- Journal Title
  
  BMC Cancer
  
  Volume: 20 Issue: 1 Pages: 336-336
- DOI
  10.1186/s12885-020-06716-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22574, KAKENHI-PROJECT-20H03694, KAKENHI-PROJECT-17H06162
[Journal Article] The critical role of CD4+ T cells in PD-1 blockade against MHC-II?expressing tumors such as classic Hodgkin lymphoma2020
- Author(s)
  Nagasaki Joji、Togashi Yosuke、Sugawara Takeaki、Itami Makiko、Yamauchi Nobuhiko、Yuda Junichiro、Sugano Masato、Ohara Yuuki、Minami Yosuke、Nakamae Hirohisa、Hino Masayuki、Takeuchi Masahiro、Nishikawa Hiroyoshi
- Journal Title
  
  Blood Advances
  
  Volume: 4 Issue: 17 Pages: 4069-4082
- DOI
  10.1182/bloodadvances.2020002098
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03694, KAKENHI-PROJECT-19K22574, KAKENHI-PROJECT-17H06162
[Journal Article] Regorafenib Plus Nivolumab in Patients With Advanced Gastric or Colorectal Cancer: An Open-Label, Dose-Escalation, and Dose-Expansion Phase Ib Trial (REGONIVO, EPOC1603)2020
- Author(s)
  Fukuoka Shota、Hara Hiroki、Takahashi Naoki、Kojima Takashi、Kawazoe Akihito、Asayama Masako、Yoshii Takako、Kotani Daisuke、Tamura Hitomi、Mikamoto Yuichi、Hirano Nami、Wakabayashi Masashi、Nomura Shogo、Sato Akihiro、Kuwata Takeshi、Togashi Yosuke、Nishikawa Hiroyoshi、Shitara Kohei
- Journal Title
  
  Journal of Clinical Oncology
  
  Volume: 38 Issue: 18 Pages: 2053-2061
- DOI
  10.1200/jco.19.03296
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03694, KAKENHI-PROJECT-19K22574, KAKENHI-PROJECT-17H06162
[Journal Article] Heterogeneity in congenital melanocytic nevi contributes to multicentric melanomagenesis2020
- Author(s)
  Honobe Akiko、Sakai Kazuko、Togashi Yosuke、Ohnuma Takehiro、Kawamura Tatsuyoshi、Nishio Kazuto、Inozume Takashi
- Journal Title
  
  Journal of Dermatological Science
  
  Volume: 100 Issue: 3 Pages: 217-219
- DOI
  10.1016/j.jdermsci.2020.09.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08744, KAKENHI-PROJECT-20H03694, KAKENHI-PROJECT-19K22574, KAKENHI-PROJECT-19K17794
[Journal Article] Blockade of EGFR improves responsiveness to PD-1 blockade in EGFR-mutated non?small cell lung cancer2020
- Author(s)
  Sugiyama Eri、Togashi Yosuke、Takeuchi Yoshiko、Shinya Sayoko、Tada Yasuko、Kataoka Keisuke、Tane Kenta、Sato Eiichi、Ishii Genichiro、Goto Koichi、Shintani Yasushi、Okumura Meinoshin、Tsuboi Masahiro、Nishikawa Hiroyoshi
- Journal Title
  
  Science Immunology
  
  Volume: 5 Issue: 43 Pages: 3937-3937
- DOI
  10.1126/sciimmunol.aav3937
- NAID
  120006845852
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22574, KAKENHI-PROJECT-19H03729, KAKENHI-PROJECT-17H06162
[Journal Article] Association between the mutational smoking signature and the immune microenvironment in lung adenocarcinoma2020
- Author(s)
  Sato Kei、Mimaki Sachiyo、Yamashita Riu、Togashi Yosuke、Naito Tomoyuki、Udagawa Hibiki、Katsumata Shinya、Nakasone Shoko、Miyoshi Tomohiro、Tane Kenta、Aokage Keiju、Sugano Masato、Kojima Motohiro、Fujii Satoshi、Kuwata Takeshi、Ochiai Atsushi、Goto Koichi、Tsuboi Masahiro、Tsuchihara Katsuya、Ishii Genichiro
- Journal Title
  
  Lung Cancer
  
  Volume: 147 Pages: 12-20
- DOI
  10.1016/j.lungcan.2020.06.029
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03694, KAKENHI-PROJECT-18K07035, KAKENHI-PROJECT-19K22574
[Journal Article] The PD-1 expression balance between effector and regulatory T cells predicts the clinical efficacy of PD-1 blockade therapies2020
- Author(s)
  Kumagai S,Togashi Y,Kamada T,Sugiyama E,Nishinakamura H,Takeuchi Y,Vitaly K,Itahashi K,Maeda Y,Matsui S,Shibahara T,Yamashita Y,Irie T,Tsuge A,Fukuoka S,Kawazoe A,Udagawa H,Kirita K,Aokage K,Ishii G,Kuwata T,Nakama K,Kawazu M,Ueno T,Yamazaki N,Goto K,Tsuboi M,Mano H,Doi T,Shitara K,Nishikawa H
- Journal Title
  
  Nature Immunology
  
  Volume: 21 Issue: 11 Pages: 1346-1358
- DOI
  10.1038/s41590-020-0769-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08531, KAKENHI-PROJECT-20H03694, KAKENHI-PROJECT-18J21551, KAKENHI-PROJECT-18K07320, KAKENHI-PROJECT-19K22574, KAKENHI-PROJECT-17K15738, KAKENHI-PROJECT-17H06162
[Journal Article] An Oncogenic Alteration Creates a Microenvironment that Promotes Tumor Progression by Conferring a Metabolic Advantage to Regulatory T Cells2020
- Author(s)
  Shogo Kumagai, Yosuke Togashi, Chika Sakai, Akihito Kawazoe, Masahito Kawazu, Toshihide Ueno, Eiichi Sato, Takeshi Kuwata, Takahiro Kinoshita, Masami Yamamoto, Sachiyo Nomura, Tetsuya Tsukamoto, Hiroyuki Mano, Kohei Shitara, Hiroyoshi Nishikawa
- Journal Title
  
  Immunity
  
  Volume: 14 Issue: 1 Pages: 187-203
- DOI
  10.1016/j.immuni.2020.06.016
- NAID
  120006952281
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06408, KAKENHI-PROJECT-19H03729, KAKENHI-PROJECT-20H03694, KAKENHI-PROJECT-18J21551, KAKENHI-PROJECT-18K07320, KAKENHI-PROJECT-19K22574, KAKENHI-PROJECT-17H06162
[Journal Article] Analysis of the tumor reactivity of tumor-infiltrating lymphocytes in a metastatic melanoma lesion that lost MHC class I expression after anti-PD-1 therapy.2019
- Author(s)
  Inozume T, Yaguchi T, Ariyasu R, Togashi Y, Ohnuma T, Honobe A, Nishikawa H, Kawakami Y, Kawamura T.
- Journal Title
  
  J Invest Dermatol.
  
  Volume: 印刷中 Issue: 7 Pages: 30023-5
- DOI
  10.1016/j.jid.2019.01.007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08309, KAKENHI-PROJECT-26221005, KAKENHI-PROJECT-16K10148, KAKENHI-PROJECT-17K16335, KAKENHI-PROJECT-17K18388, KAKENHI-PROJECT-17H06162, KAKENHI-PROJECT-19K08744, KAKENHI-PROJECT-19K17794
[Journal Article] PD-1+ regulatory T cells amplified by PD-1 blockade promote hyperprogression of cancer2019
- Author(s)
  Kamada Takahiro、Togashi Yosuke、Tay Christopher、Ha Danbee、Sasaki Akinori、Nakamura Yoshiaki、Sato Eiichi、Fukuoka Shota、Tada Yasuko、Tanaka Atsushi、Morikawa Hiromasa、Kawazoe Akihito、Kinoshita Takahiro、Shitara Kohei、Sakaguchi Shimon、Nishikawa Hiroyoshi
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: In press Issue: 20 Pages: 9999-10008
- DOI
  10.1073/pnas.1822001116
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K18388, KAKENHI-PROJECT-19K22574, KAKENHI-PROJECT-16H06295, KAKENHI-PROJECT-19H03729, KAKENHI-PROJECT-17H06162
[Journal Article] Clinical and immune profiling for cancer of unknown primary site.2019
- Author(s)
  Haratani K, Hayashi H, Takahama T, Nakamura Y, Tomida S, Yoshida T, Chiba Y, Sawada T, Sakai K, Fujita Y, Togashi Y, Tanizaki J, Kawakami H, Ito A, Nishio K, Nakagawa K
- Journal Title
  
  Journal for immunotherapy of cancer
  
  Volume: 7 Issue: 1 Pages: 251-251
- DOI
  10.1186/s40425-019-0720-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07049, KAKENHI-PROJECT-19K22574, KAKENHI-PLANNED-17H06404, KAKENHI-PROJECT-17K07204, KAKENHI-PROJECT-17K10784
[Journal Article] Selective inhibition of low-affinity memory CD8+ T cells by corticosteroids2019
- Author(s)
  Tokunaga Akihiro、Sugiyama Daisuke、Maeda Yuka、Warner Allison Betof、Panageas Katherine S.、Ito Sachiko、Togashi Yosuke、Sakai Chika、Wolchok Jedd D.、Nishikawa Hiroyoshi
- Journal Title
  
  Journal of Experimental Medicine
  
  Volume: 216 Issue: 12 Pages: 2701-2713
- DOI
  10.1084/jem.20190738
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22574, KAKENHI-PROJECT-17K15738, KAKENHI-PROJECT-17H06162
[Journal Article] Regulatory T cells in cancer immunosuppression ? implications for anticancer therapy2019
- Author(s)
  Togashi Yosuke、Shitara Kohei、Nishikawa Hiroyoshi
- Journal Title
  
  Nature Reviews Clinical Oncology
  
  Volume: In press Issue: 6 Pages: 356-371
- DOI
  10.1038/s41571-019-0175-7
- NAID
  40022082775
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K18388, KAKENHI-PROJECT-17H06162
[Journal Article] Immune suppression by PD-L2 against spontaneous and treatment-related antitumor immunity2019
- Author(s)
  Tanegashima Tokiyoshi、Togashi Yosuke、Azuma Koichi、Kawahara Akihiko、Ideguchi Ko、Sugiyama Daisuke、Kinoshita Fumio、Akiba Jun、Kashiwagi Eiji、Takeuchi Ario、Irie Takuma、Tatsugami Katsunori、Hoshino Tomoaki、Eto Masatoshi、Nishikawa Hiroyoshi
- Journal Title
  
  Clinical Cancer Research
  
  Volume: In press Issue: 15 Pages: 4808-4819
- DOI
  10.1158/1078-0432.ccr-18-3991
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K18388, KAKENHI-PROJECT-19K22574, KAKENHI-PROJECT-17H06162
[Journal Article] Mutational activation of the epidermal growth factor receptor down-regulates major histocompatibility complex class I expression via the extracellular signal-regulated kinase in non-small cell lung cancer.2018
- Author(s)
  Watanabe S, Hayashi H, Haratani K, Shimizu S, Tanizaki J, Sakai K, Kawakami H, Yonesaka K, Tsurutani J, Togashi Y, Nishio K, Ito A, Nakagawa K.
- Journal Title
  
  Cancer Sci.
  
  Volume: 110(1) Issue: 1 Pages: 52-60
- DOI
  10.1111/cas.13860
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06404, KAKENHI-PROJECT-17K18388
[Journal Article] Targeting VEGFR2 with Ramucirumab strongly impacts effector/ activated regulatory T cells and CD8+ T cells in the tumor microenvironment2018
- Author(s)
  Tada Yasuko、Togashi Yosuke、Kotani Daisuke、Kuwata Takeshi、Sato Eichi、Kawazoe Akihito、Doi Toshihiko、Wada Hisashi、Nishikawa Hiroyoshi、Shitara Kohei
- Journal Title
  
  Journal for ImmunoTherapy of Cancer
  
  Volume: 6 Issue: 1 Pages: 106-106
- DOI
  10.1186/s40425-018-0403-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K18388, KAKENHI-PROJECT-17H06162
[Journal Article] Clinicopathological features of 22C3 PD-L1 expression with mismatch repair, Epstein?Barr virus status, and cancer genome alterations in metastatic gastric cancer2018
- Author(s)
  Kawazoe Akihito、Shitara Kohei、Kuboki Yasutoshi、Bando Hideaki、Kojima Takashi、Yoshino Takayuki、Ohtsu Atsushi、Ochiai Atsushi、Togashi Yosuke、Nishikawa Hiroyoshi、Doi Toshihiko、Kuwata Takeshi
- Journal Title
  
  Gastric Cancer
  
  Volume: 22 Issue: 1 Pages: 69-76
- DOI
  10.1007/s10120-018-0843-9
- NAID
  40021775208
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07007, KAKENHI-PROJECT-17K18388, KAKENHI-PROJECT-17H06162
[Journal Article] Efficacy of irreversible EGFR-TKIs for the uncommon secondary resistant EGFR mutations L747S, D761Y, and T854A.2017
- Author(s)
  Chiba M, Togashi Y, Bannno E, Kobayashi Y, Nakamura Y, Hayashi H, Terashima M, De Velasco MA, Sakai K, Fujita Y, Mitsudomi T, Nishio K.
- Journal Title
  
  BMC Cancer.
  
  Volume: 17 Issue: 1 Pages: 281-281
- DOI
  10.1186/s12885-017-3263-z
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05433, KAKENHI-PROJECT-15H06754, KAKENHI-PROJECT-17K18388, KAKENHI-PROJECT-17J09900
[Journal Article] Clinical significance of Akt2 in advanced pancreatic cancer treated with erlotinib.2017
- Author(s)
  Banno E, Togashi Y, de Velasco MA, Mizukami T, Nakamura Y, Terashima M, Sakai K, Fujita Y, Kamata K, Kitano M, Kudo M, Nishio K
- Journal Title
  
  Int J Oncol
  
  Volume: 50 Issue: 6 Pages: 2049-2058
- DOI
  10.3892/ijo.2017.3961
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09410, KAKENHI-PROJECT-17K18388, KAKENHI-PLANNED-17H06404, KAKENHI-PROJECT-17J09900
[Journal Article] Tumor Immune Microenvironment and Nivolumab Efficacy in EGFR Mutation-Positive Non-Small Cell Lung Cancer Based on T790M Status After Disease Progression During EGFR-TKI Treatment2017
- Author(s)
  K. Haratani, H. Hayashi*, T. Tanaka, H. Kaneda, Y. Togashi, K. Sakai, K. Hayashi, S. Tomida, Y. Chiba, K. Yonesaka, Y. Nonagase, T. Takahama, J. Tanizaki, K. Tanaka, T. Yoshida, K. Tanimura, M. Takeda, H. Yoshioka, T. Ishida, T. Mitsudomi, K. Nishio and K. Nakagawa
- Journal Title
  
  Annals of Oncology
  
  Volume: in press Issue: 7 Pages: 1532-1539
- DOI
  10.1093/annonc/mdx183
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16K21506, KAKENHI-PROJECT-17K18388, KAKENHI-PUBLICLY-16H01574, KAKENHI-PLANNED-17H06404, KAKENHI-PROJECT-17J09900
[Journal Article] Regulatory T Cells: Molecular and Cellular Basis for Immunoregulation2017
- Author(s)
  Togashi Yosuke、Nishikawa Hiroyoshi
- Journal Title
  
  Current Topics Microbiology and Immunology
  
  Volume: 410 Pages: 3-27
- DOI
  10.1007/82_2017_58
- ISBN
  9783319689289, 9783319689296
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K18388, KAKENHI-PROJECT-17J09900, KAKENHI-PROJECT-16K15551, KAKENHI-PROJECT-17H06162
[Journal Article] Suppression from beyond the grave2017
- Author(s)
  Togashi Yosuke、Nishikawa Hiroyoshi
- Journal Title
  
  Nature Immunology
  
  Volume: 18 Issue: 12 Pages: 1285-1286
- DOI
  10.1038/ni.3870
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K18388, KAKENHI-PROJECT-17J09900, KAKENHI-PROJECT-16K15551, KAKENHI-PROJECT-17H06162
[Journal Article] Significance of FGF9 gene in resistance to anti-EGFR therapies targeting colorectal cancer: a subset of colorectal cancer patients with FGF9 upregulation may be resistant to anti-EGFR therapies2016
- Author(s)
  Mizukami T, Togashi Y, Naruki S, Banno E, Terashima M, De Velasco MA, Sakai K, Yoneshige A, Hayashi H, Fujita Y, Tomida S, Nakajima TE, Fujino T, Boku N, Ito A, Nakagawa K, Nishio K.
- Journal Title
  
  Molecular Carcinogenesis
  
  Volume: Epub Issue: 1 Pages: 106-117
- DOI
  10.1002/mc.22476
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H06754, KAKENHI-PROJECT-15K15113
[Journal Article] Sensitivities to various EGFR-TKIs of uncommon EGFR mutations L861Q and S768I: what is the optimal EGFR-TKI?2016
- Author(s)
  Banno E, Togashi Y, Nakamura Y, Chiba M, Kobayashi Y, Hayashi H, Terashima M, de Velasco MA, Sakai K, Fujita Y, Mitsudomi T, Nishio K.
- Journal Title
  
  Cancer Science
  
  Volume: 107 Issue: 8 Pages: 1134-1140
- DOI
  10.1111/cas.12980
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H06754
[Journal Article] MEK inhibitors against MET-amplified non-small cell lung cancer.2016
- Author(s)
  Chiba M, Togashi Y, Tomida S, Mizuuchi H, Nakamura Y, Banno E, Hayashi H, Terashima M, De Velasco MA, Sakai K, Fujita Y, Mitsudomi T, Nishio K.
- Journal Title
  
  Int J Oncol.
  
  Volume: 49 Issue: 6 Pages: 2236-2244
- DOI
  10.3892/ijo.2016.3736
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01574, KAKENHI-PROJECT-15H06754
[Journal Article] Afatinib against Esophageal or Head-and-Neck Squamous Cell Carcinoma: Significance of Activating Oncogenic HER4 Mutations in HNSCC.2016
- Author(s)
  Nakamura Y, Togashi Y, Nakahara H, Tomida S, Banno E, Terashima M, Hayashi H, de Velasco MA, Sakai K, Fujita Y, Okegawa T, Nutahara K, Hamada S, Nishio K.
- Journal Title
  
  Mol Cancer Ther.
  
  Volume: 15 Issue: 8 Pages: 1988-1997
- DOI
  10.1158/1535-7163.mct-15-0737
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01574, KAKENHI-PROJECT-15H06754, KAKENHI-PROJECT-16K11696
[Journal Article] Functional analyses of mutations in receptor tyrosine kinase genes in non-small cell lung cancer: double-edged sword of DDR22016
- Author(s)
  Terashima M, Togashi Y, Sato K, Mizuuchi H, Sakai K, Suda K, Nakamura Y, Banno E, Hayashi H, De Velasco MA, Fujita Y, Tomida S, Mitsudomi T, Nishio K.
- Journal Title
  
  Clinical Cancer Research
  
  Volume: 22 Issue: 14 Pages: 3663-3671
- DOI
  10.1158/1078-0432.ccr-15-2093
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H06754
[Patent] 免疫チェックポイント阻害剤効果判定バイオマーカー2018
- Inventor(s)
  西川博嘉、冨樫庸介、大山行也、吉田隆雄、竹田和彦、幸田健一
- Industrial Property Rights Holder
  西川博嘉、冨樫庸介、大山行也、吉田隆雄、竹田和彦、幸田健一
- Industrial Property Rights Type
  特許
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-17K18388
[Presentation] Single-cell sequencing for a tumor microenvironment2022
- Author(s)
  Yosuke Togashi
- Organizer
  第19回日本臨床腫瘍学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03694
[Presentation] 胸部腫瘍（非小細胞肺癌を除く）に対する複合免疫療法を考える2021
- Author(s)
  冨樫庸介
- Organizer
  第62回日本肺癌学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03694
[Presentation] 腫瘍微小環境におけるクローン進展2021
- Author(s)
  冨樫庸介
- Organizer
  第34回バイオセラピー学会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03694
[Presentation] Emerging biomarker for immunotherapy in head and neck cancer2021
- Author(s)
  Yosuke Togashi
- Organizer
  第18回日本臨床腫瘍学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19K22574
[Presentation] Efficacy Predictors of Preoperative CRT and Consolidation Nivolumab in Patients with Locally Advanced Rectal Cancer.2021
- Author(s)
  Koji Inamori, Yosuke Togashi, Hideaki Bando, Yuichiro Tsukada, Shota Fukuoka,Yutaka Suzuki, Daisuke Kotani, Motohiro Kojima, Makoto Fukui, Satoshi Yuki, Yoshito Komatsu, Shigenori Homma, Akinobu Taketomi, Mamoru Uemura, Takeshi Kato, Masaaki Ito, Hiroyoshi Nishikawa, Takayuki Yoshino.
- Organizer
  第18回日本臨床腫瘍学会学術集会
- Data Source
  KAKENHI-PROJECT-20H03694
[Presentation] Heterogeneity in congenital melanocytic nevi contributes to muliticentric melanomagenesis.2021
- Author(s)
  Takashi Inozume, Akiko Honobe, Kazuko Sakai, Yosuke Togashi, Takehiro Ohnura, Tatsuyoshi Kawamura, Kazuto Nishio
- Organizer
  第18回日本臨床腫瘍学会学術集会
- Data Source
  KAKENHI-PROJECT-19K22574
[Presentation] The Future of Immunotherapy2021
- Author(s)
  Yosuke Togashi
- Organizer
  2021 Targeted Therapy of Lung Cancer Meeting
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22574
[Presentation] CD155/TIGIT axisは免疫チェックポイント阻害剤のinflamed resistanceに関与する2021
- Author(s)
  猪爪隆史, 川島秀介, 河津正人, 池原譲, 木庭幸子, 中村泰大, 梅田善康, 川崎朋範, 川村龍吉, 大沼毅紘, 保延亜希子, 冨樫庸介
- Organizer
  日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-20H03694
[Presentation] The critical role of CD4+ T cells in PD-1 blockade against MHC-II-expressing tumors such as classic Hodgkin lymphoma2021
- Author(s)
  Joji Nagasaki1, Yosuke Togashi, Takeaki Sugawara, Makiko Itami, Nobuhiko Yamauchi, Junichiro Yuda, Sugano Masato, Ohara Yuuki, Yosuke Minami, Hirohisa Nakamae, Masayuki Hino, Masahiro Takeuchi, Hiroyoshi Nishikawa.
- Organizer
  第18回日本臨床腫瘍学会学術集会
- Data Source
  KAKENHI-PROJECT-20H03694
[Presentation] Precision Medicine of Cancer Immunotherapy2021
- Author(s)
  Yosuke Togashi
- Organizer
  第80回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03694
[Presentation] Translational Research of VOLTAGE-A: Efficacy Predictors of Preoperative Chemoradiotherapy and Consolidation Nivolumab in Patients with both Microsatellite Stable and Microsatellite Instability-High Locally Advanced Rectal Cancer2021
- Author(s)
  Koji Inamori, Yosuke Togashi, Hideaki Bando, Yuichiro Tsukada, Shota Fukuoka, Ayako Suzuki, Yutaka Suzuki, Daisuke Kotani, Motohiro Kojima, Makoto Fukui, Satoshi Yuki, Yoshito Komatsu, Shigenori Homma, Akinobu Taketomi, Mamoru Uemura, Takeshi Kato, Masaaki Ito, Hiroyoshi Nishikawa, Takayuki Yoshino.
- Organizer
  ASCO-GI2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22574
[Presentation] Clonal evolution in the tumor microenvironment2021
- Author(s)
  Yosuke Togashi
- Organizer
  第18回日本臨床腫瘍学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03694
[Presentation] 中型先天性色素性母斑とそこから生じた悪性黒色腫と転移巣における遺伝子変異状況の比較2021
- Author(s)
  田渕亜希子, 大沼毅紘, 出口順啓, 島田眞路, 川村龍吉, 坂井和子, 西尾和人, 冨樫庸介, 猪爪隆史
- Organizer
  日本皮膚科学会総会
- Data Source
  KAKENHI-PROJECT-20H03694
[Presentation] 腫瘍局所における代謝機構を介した制御性T細胞の新規PD-1発現機構の解明2021
- Author(s)
  熊谷尚悟, 鎌田貴裕, 冨樫庸介, 小山正平, 川添彬人, 河津正人, 青景圭樹, 名嘉眞健太, 吉田達哉, 山崎直也, 大江裕一郎, 坪井正博, 設樂紘平, 間野博行, 西川博嘉
- Organizer
  日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-20H03694
[Presentation] Phase II Trial of Site-Specific Treatment Based on Gene Expression and Mutation Profiling by next generation sequencing (NGS) for Patients (pts) With Cancer of Unknown Primary Site (CUP)2021
- Author(s)
  Makoto Arai, Hidetoshi Hayashi, Hironobu Minami, Yuichi Takiguchi, Satomi Watanabe, Masanori Toyoda, Kohei Akiyoshi, Yoshihiko Segawa, Hiroki Ueda, Yasuo Iwamoto, Jun Masuda, Hirohumi Mukai, Toshio Kubo, Yosuke Togashi, Kazuko Sakai, Yoshihiko Fujita, Shuta Tomida, Yasutaka Chiba, Kazuto Nishio, and Kazuhiko Nakagawa
- Organizer
  第18回日本臨床腫瘍学会学術集会
- Data Source
  KAKENHI-PROJECT-20H03694
[Presentation] 免疫チェックポイント阻害剤の耐性メカニズムを考える2021
- Author(s)
  冨樫庸介
- Organizer
  第37回日本皮膚悪性腫瘍学会学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03694
[Presentation] Translational Research of VOLTAGE-A: Efficacy Predictors of Preoperative Chemoradiotherapy and Consolidation Nivolumab in Patients with both Microsatellite Stable and Microsatellite Instability-High Locally Advanced Rectal Cancer2021
- Author(s)
  Koji Inamori, Yosuke Togashi, Hideaki Bando, Yuichiro Tsukada, Shota Fukuoka, Ayako Suzuki, Yutaka Suzuki, Daisuke Kotani, Motohiro Kojima, Makoto Fukui, Satoshi Yuki, Yoshito Komatsu, Shigenori Homma, Akinobu Taketomi, Mamoru Uemura, Takeshi Kato, Masaaki Ito, Hiroyoshi Nishikawa, Takayuki Yoshino.
- Organizer
  ASCO-GI2021
- Data Source
  KAKENHI-PROJECT-20H03694
[Presentation] がん免疫とは何か：解析手法の基礎2021
- Author(s)
  冨樫庸介
- Organizer
  第80回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03694
[Presentation] TIGIT/CD155 axis mediates resistance to immunotherapies in inflamed tumors.2021
- Author(s)
  Shusuke Kawashima, Takashi Inozume, Masahito Kawazu, Etsuko Tanji, Akiko Honobe, Takehiro Ohnuma, Tatsuyoshi Kawamura, Hiroyuki Matsue, Yosuke Togashi.
- Organizer
  第18回日本臨床腫瘍学会学術集会
- Data Source
  KAKENHI-PROJECT-19K22574
[Presentation] The critical role of CD4+ T cells in PD-1 blockade against MHC-II-expressing tumors such as classic Hodgkin lymphoma.2021
- Author(s)
  Joji Nagasaki1, Yosuke Togashi, Takeaki Sugawara, Makiko Itami, Nobuhiko Yamauchi, Junichiro Yuda, Sugano Masato, Ohara Yuuki, Yosuke Minami, Hirohisa Nakamae, Masayuki Hino, Masahiro Takeuchi, Hiroyoshi Nishikawa.
- Organizer
  第18回日本臨床腫瘍学会学術集会
- Data Source
  KAKENHI-PROJECT-19K22574
[Presentation] Clonal evolution in the tumor microenvironment2021
- Author(s)
  Yosuke Togashi
- Organizer
  第18回日本臨床腫瘍学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19K22574
[Presentation] Heterogeneity in congenital melanocytic nevi contributes to muliticentric melanomagenesis.2021
- Author(s)
  Takashi Inozume, Akiko Honobe, Kazuko Sakai, Yosuke Togashi, Takehiro Ohnura, Tatsuyoshi Kawamura, Kazuto Nishio
- Organizer
  第18回日本臨床腫瘍学会学術集会
- Data Source
  KAKENHI-PROJECT-20H03694
[Presentation] Efficacy Predictors of Preoperative CRT and Consolidation Nivolumab in Patients with Locally Advanced Rectal Cancer2021
- Author(s)
  Koji Inamori, Yosuke Togashi, Hideaki Bando, Yuichiro Tsukada, Shota Fukuoka,Yutaka Suzuki, Daisuke Kotani, Motohiro Kojima, Makoto Fukui, Satoshi Yuki, Yoshito Komatsu, Shigenori Homma, Akinobu Taketomi, Mamoru Uemura, Takeshi Kato, Masaaki Ito, Hiroyoshi Nishikawa, Takayuki Yoshino.
- Organizer
  第18回日本臨床腫瘍学会学術集会
- Data Source
  KAKENHI-PROJECT-19K22574
[Presentation] Cancer immunogenomics for the next stage of precision medicine2021
- Author(s)
  Yosuke Togashi
- Organizer
  第25回国際がん化学療法シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-20H03694
[Presentation] TIGIT/CD155 axis mediates resistance to immunotherapies in inflamed tumors.2021
- Author(s)
  Shusuke Kawashima, Takashi Inozume, Masahito Kawazu, Etsuko Tanji, Akiko Honobe, Takehiro Ohnuma, Tatsuyoshi Kawamura, Hiroyuki Matsue, Yosuke Togashi.
- Organizer
  第18回日本臨床腫瘍学会学術集会
- Data Source
  KAKENHI-PROJECT-20H03694
[Presentation] The Future of Immunotherapy2021
- Author(s)
  Yosuke Togashi
- Organizer
  2021 Targeted Therapy of Lung Cancer Meeting
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03694
[Presentation] Emerging biomarker for immunotherapy in head and neck cancer2021
- Author(s)
  Yosuke Togashi
- Organizer
  第18回日本臨床腫瘍学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03694
[Presentation] Several types of “exhausted” T cells in the tumor microenvironment2021
- Author(s)
  Yosuke Togashi
- Organizer
  第50回日本免疫学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03694
[Presentation] Phase II Trial of Site-Specific Treatment Based on Gene Expression and Mutation Profiling by next generation sequencing (NGS) for Patients (pts) With Cancer of Unknown Primary Site (CUP)2021
- Author(s)
  Makoto Arai, Hidetoshi Hayashi, Hironobu Minami, Yuichi Takiguchi, Satomi Watanabe, Masanori Toyoda, Kohei Akiyoshi, Yoshihiko Segawa, Hiroki Ueda, Yasuo Iwamoto, Jun Masuda, Hirohumi Mukai, Toshio Kubo, Yosuke Togashi, Kazuko Sakai, Yoshihiko Fujita, Shuta Tomida, Yasutaka Chiba, Kazuto Nishio, and Kazuhiko Nakagawa.
- Organizer
  第18回日本臨床腫瘍学会学術集会
- Data Source
  KAKENHI-PROJECT-19K22574
[Presentation] Translational Research for Future Immunotherapy2020
- Author(s)
  冨樫庸介
- Organizer
  第92回日本胃癌学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-19K22574
[Presentation] Cancer immunogenomics2020
- Author(s)
  Yosuke Togashi
- Organizer
  KSMO and JSMO Joint Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22574
[Presentation] 免疫チェックポイント阻害剤を含む併用療法におけるバイオマーカー2020
- Author(s)
  冨樫庸介
- Organizer
  第60回日本呼吸器学会学術講演会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03694
[Presentation] 腫瘍に発現するPD-L2の免疫抑制機能について2020
- Author(s)
  種子島時祥, 冨樫庸介, 東公一, 入江拓磨, 木下史生, 柏木英志, 武内在雄, 立神勝則, 江藤正俊, 西川博嘉
- Organizer
  第108回日本泌尿器科学総会
- Data Source
  KAKENHI-PROJECT-20H03694
[Presentation] 免疫チェックポイント阻害剤と制御性T細胞2020
- Author(s)
  冨樫庸介
- Organizer
  第24回日本がん分子標的治療学会
- Invited
- Data Source
  KAKENHI-PROJECT-19K22574
[Presentation] Translational Research for Future Immunotherapy2020
- Author(s)
  冨樫庸介
- Organizer
  第92回日本胃癌学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03694
[Presentation] 免疫チェックポイント阻害剤と制御性T細胞2020
- Author(s)
  冨樫庸介
- Organizer
  第24回日本がん分子標的治療学会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03694
[Presentation] Translational Research using Clinical Samples in Cancer Immunology2020
- Author(s)
  Yosuke Togashi
- Organizer
  第79回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-19K22574
[Presentation] Short-Term Results of VOLTAGE-A: Nivolumab Monotherapy and Subsequent Radical Surgery Following Preoperative Chemoradiotherapy in Patients with Microsatellite Stable and Microsatellite Instability-High Locally Advanced Rectal Cancer.2020
- Author(s)
  Satoshi Yuki, Hideaki Bando, Yuichiro Tsukada, Koji Inamori, Yoshito Komatsu, Shigenori Homma, Mamoru Uemura, Takeshi Kato, Daisuke Kotani, Shota Fukuoka, Naoki Nakamura, Makoto Fukui, Masashi Wakabayashi, Motohiro Kojima, Yosuke Togashi, Akihiro Sato, Hiroyoshi Nishikawa, Masaaki Ito, Takayuki Yoshino
- Organizer
  ASCO2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03694
[Presentation] 免疫チェックポイント阻害剤を含む併用療法におけるバイオマーカー2020
- Author(s)
  冨樫庸介
- Organizer
  第60回日本呼吸器学会学術講演会
- Invited
- Data Source
  KAKENHI-PROJECT-19K22574
[Presentation] Translational Research using Clinical Samples in Cancer Immunology2020
- Author(s)
  Yosuke Togashi
- Organizer
  第79回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03694
[Presentation] PD-L2による、自発的・治療関連抗腫瘍免疫に対する免疫抑制機能2020
- Author(s)
  種子島時祥, 冨樫庸介, 江藤正俊, 西川博嘉
- Organizer
  第72回西日本泌尿器科学総会
- Data Source
  KAKENHI-PROJECT-19K22574
[Presentation] Translational research of voltage-A1: Efficacy predictors of preoperative chemoradiotherapy and subsequent nivolumab monotherapy in patients with microsatellite-stable locally advanced rectal cancer2020
- Author(s)
  Koji Inamori, Yosuke Togashi, Hideaki Bando, Yuichiro Tsukada, Shota Fukuoka, Ayako Suzuki, Yutaka Suzuki, Daisuke Kotani, Motohiro Kojima, Makoto Fukui, Satoshi Yuki, Yoshito Komatsu, Shigenori Homma, Akinobu Taketomi, Mamoru Uemura, Takeshi Kato, Masaaki Ito, Hiroyoshi Nishikawa, Takayuki Yoshino
- Organizer
  ASCO2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22574
[Presentation] Short-Term Results of VOLTAGE-A: Nivolumab Monotherapy and Subsequent Radical Surgery Following Preoperative Chemoradiotherapy in Patients with Microsatellite Stable and Microsatellite Instability-High Locally Advanced Rectal Cancer.2020
- Author(s)
  Satoshi Yuki, Hideaki Bando, Yuichiro Tsukada, Koji Inamori, Yoshito Komatsu, Shigenori Homma, Mamoru Uemura, Takeshi Kato, Daisuke Kotani, Shota Fukuoka, Naoki Nakamura, Makoto Fukui, Masashi Wakabayashi, Motohiro Kojima, Yosuke Togashi, Akihiro Sato, Hiroyoshi Nishikawa, Masaaki Ito, Takayuki Yoshino
- Organizer
  ASCO2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22574
[Presentation] Cancer immunogenomics2020
- Author(s)
  Yosuke Togashi
- Organizer
  KSMO and JSMO Joint Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03694
[Presentation] Translational research of voltage-A1: Efficacy predictors of preoperative chemoradiotherapy and subsequent nivolumab monotherapy in patients with microsatellite-stable locally advanced rectal cancer.2020
- Author(s)
  Koji Inamori, Yosuke Togashi, Hideaki Bando, Yuichiro Tsukada, Shota Fukuoka, Ayako Suzuki, Yutaka Suzuki, Daisuke Kotani, Motohiro Kojima, Makoto Fukui, Satoshi Yuki, Yoshito Komatsu, Shigenori Homma, Akinobu Taketomi, Mamoru Uemura, Takeshi Kato, Masaaki Ito, Hiroyoshi Nishikawa, Takayuki Yoshino
- Organizer
  ASCO2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03694
[Presentation] PD-L2による、自発的・治療関連抗腫瘍免疫に対する免疫抑制機能2020
- Author(s)
  種子島時祥, 冨樫庸介, 江藤正俊, 西川博嘉
- Organizer
  第72回西日本泌尿器科学総会
- Data Source
  KAKENHI-PROJECT-20H03694
[Presentation] 腫瘍に発現するPD-L2の免疫抑制機能について2020
- Author(s)
  種子島時祥, 冨樫庸介, 東公一, 入江拓磨, 木下史生, 柏木英志, 武内在雄, 立神勝則, 江藤正俊, 西川博嘉
- Organizer
  第108回日本泌尿器科学総会
- Data Source
  KAKENHI-PROJECT-19K22574
[Presentation] An Open Label Phase I Study to Evaluate the Safety and Efficacy of OBP-301 With Pembrolizumab in Patients With Advanced Solid Tumors (EPOC1505)2019
- Author(s)
  Takashi Kojima, Toshiyoshi Fujiwara, Yasuhiro Shirakawa, Keisuke Hori, Hiromi Ono, Masako Nakamoto, Hiromi Hasegawa, Nami Hirano, Masashi Wakabayashi, Shogo Nomura, Yosuke Togashi, Hiroyoshi Nishikawa, Akihiro Sato, Atsushi Ohtsu, Toshihiko Doi
- Organizer
  AACR Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22574
[Presentation] Efficacy of Radiotherapy to Primary Tumor After Nivolumab Treatment in Patients with Advanced Gastric Cancer2019
- Author(s)
  Akinori Sasaki, Yoshiaki Nakamura, Hirofumi Kuno, Yosuke Togashi, Hidehiro Hojo, Kenji Takashima, Tomohiro Kadota, Saori Mishima, Daisuke Kotani, Akihito Kawazoe, Yasutoshi Kuboki, Hiroya Taniguchi,Takayuki Yoshino, Tatsushi Kobayashi, Hiroyoshi Nishikawa, Naoki Nakamura, Tomonori Yano, Kohei Shitara
- Organizer
  第17回日本臨床腫瘍学会学術集会
- Data Source
  KAKENHI-PROJECT-19K22574
[Presentation] The PD-1 expression balance between effector and regulatory T cell predicts the clinical efficacy of PD-1 blockade therapies2019
- Author(s)
  Yosuke Togashi, Takahiro Kamada, Eri Sugiyama, Shota Fukuoka, Akihito Kawazoe, Hibiki Udagawa, Keisuke Kirita, Koichi Goto, Masahiro Tsuboi, Toshihiko Doi, Kohei Shitara, Hiroyoshi Nishikawa
- Organizer
  第17回日本臨床腫瘍学会学術集会
- Data Source
  KAKENHI-PROJECT-19K22574
[Presentation] Single cell analysis for cancer immunology2019
- Author(s)
  Togashi Yosuke
- Organizer
  第78回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-19K22574
[Presentation] 腫瘍に発現するPD-L2の免疫抑制機能について2019
- Author(s)
  種子島時祥　冨樫庸介　東公一　江藤正俊　西川博嘉
- Organizer
  第32回バイオセラピー学会
- Data Source
  KAKENHI-PROJECT-19K22574
[Presentation] Immune suppression by PD-L2 against spontaneous and treatment-related antitumor immunity2019
- Author(s)
  Tanegashima Tokiyoshi, Togashi Yosuke, Azuma Kimitoshi, Eto Masatoshi, Nishikawa Hiroyoshi
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K22574
[Presentation] A Novel Regulatory T Cell-Targeted Immunotherapy by targeting their Crucial Signal by HSP90 Inhibitors2019
- Author(s)
  Ayaka Tsuge，Yosuke Togashi，Hiroyoshi Nishikawa
- Organizer
  SITC
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22574
[Presentation] The secondary immune selection is the dominant mechanism for acquired resistance against adoptive cell therapy2019
- Author(s)
  Takahiro Kamada, Yosuke Togashi, Yoshihiro Ohue, Hiroyoshi Nishikawa
- Organizer
  AACR Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22574
[Presentation] The role of soluble immune-checkpoint factors in advanced NSCLC2019
- Author(s)
  林秀敏、茶本健司、冨樫庸介、中川和彦、本庶佑
- Organizer
  第60回日本肺癌学会学術集会
- Data Source
  KAKENHI-PROJECT-19K22574
[Presentation] Predictive Biomarkers in Cancer Immunotherapy2019
- Author(s)
  Togashi Yosuke
- Organizer
  第17回日本臨床腫瘍学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19K22574
[Presentation] Regorafenib plus nivolumab in patients with advanced gastric (GC) or colorectal cancer (CRC): an open-label, dose-finding, and dose-expansion phase 1b trial (REGONIVO, EPOC1603)2019
- Author(s)
  Shota Fukuoka, Hiroki Hara, Naoki Takahashi, Takashi Kojima, Akihito Kawazoe, Masako Asayama, Takako Yoshii, Daisuke Kotani, Hitomi Tamura, Yuichi Mikamoto, Ayako Sugama, Masashi Wakabayashi, Shogo Nomura, Akihiro Sato, Yosuke Togashi, Hiroyoshi Nishikawa, Kohei Shitara
- Organizer
  第17回日本臨床腫瘍学会学術集会
- Data Source
  KAKENHI-PROJECT-19K22574
[Presentation] TENERGY: Multicenter Phase II Study of Atezolizumab Monotherapy Following Definitive Chemoradiotherapy with 5-FU plus Cisplatin in Patients with Unresectable Locally Advanced Esophageal Squamous Cell Carcinoma2019
- Author(s)
  Hideaki Bando, Daisuke Kotani, Takahiro Tsushima, Hiroki Hara, Shigenori Kadowaki, Ken Kato, Keisho Chin, Kensei Yamaguchi, Shun-ichiro Kageyama, Hidehiro Hojo, Shogo Nomura, Miki Fukutani, Yosuke Togashi, Nozomu Fuse, Hiroyoshi Nishikawa, and Takashi Kojima
- Organizer
  ASCO Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22574
[Presentation] Regorafenib plus nivolumab in patients with advanced gastric (GC) or colorectal cancer (CRC): an open-label, dose-finding, and dose-expansion phase 1b trial (REGONIVO, EPOC1603)2019
- Author(s)
  Shota Fukuoka, Hiroki Hara, Naoki Takahashi, Takashi Kojima, Akihito Kawazoe, Masako Asayama, Takako Yoshii, Daisuke Kotani, Hitomi Tamura, Yuichi Mikamoto, Ayako Sugama, Masashi Wakabayashi, Shogo Nomura, Akihiro Sato, Yosuke Togashi, Hiroyoshi Nishikawa, Kohei Shitara
- Organizer
  ASCO Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22574
[Presentation] VOLTAGE: Investigator-initiated Clinical Trial of Nivolumab Monotherapy and Subsequent Radical Surgery Following Preoperative Chemoradiotherapy in Patients with Microsatellite Stable Locally Advanced Rectal Cancer2019
- Author(s)
  Takayuki Yoshino, Hideaki Bando, Yuichiro Tsukada, Koji Inamori, Satoshi Yuki, Yoshito Komatsu, Shigenori Homma, Mamoru Uemura, Takeshi Kato, Daisuke Kotani, Shota Fukuoka, Yosuke Togashi, Akihiro Sato, Hiroyoshi Nishikawa, Masaaki Ito
- Organizer
  ASCO Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22574
[Presentation] Multiple modalities of single cell analyses to evaluate the tumor microenvironment in clinical specimens2019
- Author(s)
  Yukie Kashima, Shota Fukuoka, Yosuke Togashi, Takahiro Kamada, Ayako Suzuki, Yoshiaki Nakamura, Kohei Shitara, Akihiro Ohashi, Taku Yoshida, Naofumi Taoka, Tatsuya Kawase, Teiji Wada, Kocihiro Inaki, Masataka Chihara, Yutaka Suzuki, Katsuya Tsuchihara, Susumu S Kobayashi, Hiroyoshi Nishikawa and Toshihiko Doi
- Organizer
  EORTC-AACR
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22574
[Presentation] The association of genomic features and immunosuppression in gastric cancer2019
- Author(s)
  Shogo Kumagai, Yosuke Togashi, Kohei Shitara, Takahiro Kinoshita, Katsuya Tsuchihara, Hiroyoshi Nishikawa
- Organizer
  AACR Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22574
[Presentation] Combination of triplet soluble immune-checkpoint factors as a complementary biomarker for the efficacy of nivolumab (nivo) in advanced non-small cell lung cancer (NSCLC) patients (pts)2019
- Author(s)
  Hidetoshi Hayashi, Kenji Chamoto, Yosuke Togashi, Kazuya Fukuoka, Ryusuke Hatae, Megumi Goto, Yasutaka Chiba, Junko Tanizaki,1,6 Koji Haratani, Takayuki Takahama, Kaoru Tanaka, Masayuki Takeda, Kazuko Sakai, Keiko Higuchi, Hitoshi Uga, Kazuto Nishio, Kazuhiko Nakagawa, Tasuku Honjo
- Organizer
  第17回日本臨床腫瘍学会学術集会
- Data Source
  KAKENHI-PROJECT-19K22574
[Presentation] EGFR-TKIによる腫瘍微小環境の免疫状態の変化2019
- Author(s)
  多根健太、宇田川響、桐田佳輔、杉山栄里、三好智裕、青影圭樹、後藤功一、坪井正博、冨樫庸介、西川博嘉
- Organizer
  第60回日本肺癌学会学術集会
- Data Source
  KAKENHI-PROJECT-19K22574
[Presentation] Novel concept of EGFR-signal contribution to unique immunological status of the tumor microenvironment in EGFR-mutated NSCLC2019
- Author(s)
  Eri Sugiyama, Yosuke Togashi, Yoshiko Takeuchi, Sayoko Shinya, Yasuko Tada, Keisuke Kataoka, Kenta Tane, Genichiro Ishii, Koichi Goto, Yasushi Shintani, Meinoshin Okumura, Masahiro Tsuboi, Hiroyoshi Nishikawa
- Organizer
  第17回日本臨床腫瘍学会学術集会
- Data Source
  KAKENHI-PROJECT-19K22574
[Presentation] A novel regulatory T cell-targeted immunotherapy via meddling the crucial signal by HSP90 inhibitors2019
- Author(s)
  Ayaka Tsuge，Yosuke Togashi，Hiroyoshi Nishikawa
- Organizer
  第48回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-19K22574
[Presentation] Clinical utility of precision immunoprofiling and monitoring tumor microenvironment by flowcytometry and CyTOF in advanced NSCLC treated with atezolizumab; results from a phase II study for biomarker analysis (EPOC1702)2019
- Author(s)
  Keisuke Kirita, Eri Sugiyama, Yosuke Togashi, Hibiki Udagawa, Shingo Matsumoto, Kiyotaka Yoh, Seiji Niho, Hiroyoshi Nishikawa and Koichi Goto
- Organizer
  第17回日本臨床腫瘍学会学術集会
- Data Source
  KAKENHI-PROJECT-19K22574
[Presentation] 脱メチル化阻害薬はMDSにおける腫瘍免疫を増強する(HMAs enhance anti-tumor effects via regulation of tumor immunity in patients with MDS)2018
- Author(s)
  湯田淳一朗, 板橋耕太, 冨樫庸介, 山内寛彦, 南陽介, 西川博嘉
- Organizer
  日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-17K18388
[Presentation] Association of gut microbiome with immune status and clinical response in solid tumor patients who received on anti-PD-1 therapies.2018
- Author(s)
  Fukuoka Shota, Daisuke Motooka, Togashi Yosuke, Sugiyama Eri, Udagawa Hibiki, Kirita Keisuke
- Organizer
  2018 ASCO Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K18388
[Presentation] Innate control of antitumor immunity by cancer cells2018
- Author(s)
  Yosuke Togashi, Eri Sugiyama, Yoshiko Takeuchi, Masahiro Tsuboi, Hiroyoshi Nishikawa
- Organizer
  Sixth JCA-AACR Special Joint Conference on the Latest Advances in Lung Cancer Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K18388
[Presentation] 免疫プロファイリングによる、濾胞性リンパ腫の予後予測2018
- Author(s)
  山内寛彦, 湯田淳一朗, 藤岡優樹, 長崎譲慈, 山崎美貴, 冨樫庸介, 南陽介, 西川博嘉
- Organizer
  日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-17K18388
[Presentation] Clinicopathological, genomic and immunological features of hyperprogressive disease during PD-1 blockade in gastric cancer patients.2018
- Author(s)
  Togashi Yosuke, Kamada Takahiro, Sasaki Akinori, Nakamura Yoshiaki, Fukuoka Shota, Tada Yasuko
- Organizer
  2018 ASCO Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K18388
[Presentation] 悪性胸膜中皮腫における腫瘍内浸潤リンパ球の検討2018
- Author(s)
  塩田哲広, 橋本健太郎, 野原淳, 石床学, 渡邉壽規, 山本喜啓, 新宅雅幸, 杉山栄里, 冨樫庸介, 西川博嘉
- Organizer
  日本肺癌学会総会
- Data Source
  KAKENHI-PROJECT-17K18388
[Presentation] 肺がん治療の進歩がん免疫治療のバイオマーカー研究2018
- Author(s)
  冨樫庸介
- Organizer
  日本癌学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-17K18388
[Presentation] Innate control of antitumor immunity by cancer cells2018
- Author(s)
  Yosuke Togashi
- Organizer
  The 33th Nagoya International Cancer Treatment Symposium
- Invited
- Data Source
  KAKENHI-PROJECT-17K18388
[Presentation] 早期がんに対するがん免疫療法―手術療法と組み合わせる試み―2018
- Author(s)
  冨樫庸介
- Organizer
  日本肺癌学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-17K18388
[Presentation] Regulatory T cells as a target in anticancer immunotherapy2018
- Author(s)
  Yosuke Togashi
- Organizer
  7th Japan-Taiwan Oncology Phase I Conference 2018
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K18388
[Presentation] Clinicopathological, Genomic and Immunological Features of Hyperprogressive Disease during PD-1 blockade in Gastric Cancer Patients2018
- Author(s)
  Yosuke Togashi, Takahiro Kamada, Akinori Sasaki, Yoshiaki Nakamura, Shota Fukuoka, Yasuko Tada, Akito Kawazoe, Kohei Shitara, Hiroyoshi Nishikawa
- Organizer
  ASCO
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K18388
[Presentation] Translational Research of Cancer Immunology in Gastric Cancer2018
- Author(s)
  Yosuke Togashi
- Organizer
  胃癌学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-17K18388
[Presentation] 大腸癌における免疫学的な新たな分類と新規がん免疫療法の可能性2018
- Author(s)
  冨樫庸介、稲守宏治、福岡聖大、杉山大介、伊藤雅昭、西川博嘉
- Organizer
  がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-17K18388
[Presentation] Basic and Translational Research in Cancer Immunology2018
- Author(s)
  Yosuke Togashi
- Organizer
  日本臨床腫瘍学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-17K18388
[Presentation] 腫瘍免疫における制御性T細胞の役割2018
- Author(s)
  冨樫庸介
- Organizer
  がん免疫学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-17K18388
[Presentation] Control of immune suppressive cells for effective cancer therapy2017
- Author(s)
  Yosuke Togashi
- Organizer
  アジア太平洋癌学会
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K18388
[Presentation] Translational Research for predictive biomarkers and novel cancer immunotherapies beyond PD-1/PD-L1 blockade therapies2017
- Author(s)
  Yosuke Togashi
- Organizer
  日本臨床腫瘍学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-17K18388
[Presentation] Clinicopathological and genetic differences between low-grade and high-grade colorectal mucinous adenocarcinoma2016
- Author(s)
  Yosuke Togashi, Yasumasa Yoshioka, Takaaki Chikugo, Akihiro Kogita, Masataka Taguri, Masato Terashima, Kazuko Sakai, Tadao Tokoro, Kiyotaka Okuno, Kazuto Nishio
- Organizer
  第14回日本臨床腫瘍学会学術集会
- Place of Presentation
  神戸
- Year and Date
  2016-07-28
- Data Source
  KAKENHI-PROJECT-15H06754
[Presentation] 稀な EGFR 遺伝子の耐性二次変異（L747S，D761 Y，T854A）における各種 EGFRTKI の感受性2016
- Author(s)
  千葉真人、冨樫庸介、西尾和人、光冨徹哉
- Organizer
  第57回日本肺癌学会
- Place of Presentation
  福岡
- Year and Date
  2016-12-19
- Data Source
  KAKENHI-PROJECT-15H06754
[Presentation] Anticancer activities of various EGFR-TKIs against uncommon EGFR-mutated non-small cell lung cancer2016
- Author(s)
  Yosuke Togashi, Masato Chiba, Eri Bannno, Yoshihisa Kobayashi, Hidetoshi Hayashi, Tetsuya Mitsudomi, and Kazuto Nishio
- Organizer
  第14回日本臨床腫瘍学会学術集会
- Place of Presentation
  神戸
- Year and Date
  2016-07-28
- Data Source
  KAKENHI-PROJECT-15H06754
[Presentation] DDR2 E655K mutations proteins are targeted for degradation by the ubiquitin-proteasome pathway and lose their functions2016
- Author(s)
  Masato Terashima, Yosuke Togashi, Kazuko Sakai, Yu Nakamura, Eri Banno, Marco A.DeVelasco, Yoshihiko Fujita, and Kazuto Nishio
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-15H06754
[Presentation] Afatinib against HNSCC or ESCC: significance of activating oncogenic HER4 mutations in HNSCC2016
- Author(s)
  Yu Nakamura, Yosuke Togashi, Masato Terashima, Marco A DeVelasco, Kazuko Sakai, Yoshihiko Fujita, Takatsugu Okegawa, Suguru Hamada, Kazuto Nishio
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-15H06754
[Presentation] Receptor tyrosine kinase mutations in non-small cell lung cancer2015
- Author(s)
  Hidetoshi Hayashi, Yosuke Togashi, Masato Terashima, Kazuko Sakai, Hiroshi Mizuuchi, Yoshihisa Kobayashi, Kenichi Suda, Kazuhiko Nakagawa, Tetsuya Mitsudomi, Kazuto Nishio
- Organizer
  European Cancer Congress 2015
- Place of Presentation
  オーストリア・ウィーン
- Year and Date
  2015-09-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H06754
[Presentation] FGF9 gene amplification can induce resistance to anti-EGFR therapy in colorectal cancer.2015
- Author(s)
  Takuro Mizukami, Yosuke Togashi, Eri Banno, Masato Terashima, Marco A de velasco, Kazuko Sakai, Hidetoshi Hayashi, Yoshihiko Fujita, Shuta Tomida, Takako Eguchi Nakajima, Narikazu Boku, Akihiko Ito, Kazuhiko Nakagawa, Kazuto Nishio
- Organizer
  European Cancer Congress 2015
- Place of Presentation
  オーストリア・ウィーン
- Year and Date
  2015-09-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H06754

1. 豊岡伸一 (30397880)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. 冨田秀太 (10372111)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
3. 枝園和彦 (30708079)

# of Collaborated Projects: 3 results

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4. 山本寛斉 (40467733)

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# of Collaborated Projects: 3 results

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7. 盛永敬郎 (30757000)

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8. Kubo Shoji (80221224)

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9. 竹村茂一 (00322363)

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12. 田中肖吾 (50382114)

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13. 岡崎幹生 (50467750)

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14. 阪口政清 (70379840)

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15. 小笠原定久 (20749155)

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16. 片岡圭亮 (90631383)

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17. 木暮泰寛 (40782389)

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18. 宝田剛志 (30377428)

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19. 本田知之 (80402676)

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20. 花澤豊行 (90272327)

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21. 江口傑徳 (20457229)

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22. 河合穂高 (10803687)

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23. 高橋賢 (50432258)

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24. 岡元邦彰 (10311846)

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25. 伊達慶一 (30974860)

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26. Tsuboi Masahiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
27. Shitara Kohei

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
28. YAGUCHI Tomonori

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. TAKIGUCHI Yuuichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. KOJIMA Motohiro

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# of Collaborated Products: 1 results
31. MITSUDOMI Tetsuya

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# of Collaborated Products: 1 results
32. KOBAYASHI Yoshihisa

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# of Collaborated Products: 1 results
33. KUDO Masatoshi

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# of Collaborated Products: 1 results
34. KITANO Masayuki

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# of Collaborated Products: 1 results
35. Doi Toshihiko

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# of Collaborated Products: 1 results
36. NISHINAKAMURA Hitomi

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# of Collaborated Products: 1 results
37. YAMAMOTO Masami

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# of Collaborated Products: 1 results
38. 河上裕

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39. 伊藤彰彦

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40. 西尾和人

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41. 林秀敏

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42. 坂井和子

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43. 西川博嘉

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44. 桑田健

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45. 元井紀子

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46. 河野隆志

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47. 北中明

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48. 池原譲

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49. 板橋耕太

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50. 小笠原康悦

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Togashi Yosuke 冨樫 庸介

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腫瘍微小環境のゲノム異常とクローン性造血の関係解明Principal Investigator

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Spatiotemporal T-cell differentiation dynamics in the tumor "peripheral" environmentPrincipal Investigator

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Analysis of PD-1+ tumor-infiltrating T cells according to cancer antigen hierarchyPrincipal Investigator

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Novel immunoediting mechanisms via somatic mutationsPrincipal Investigator

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Gene alterations and anti-tumor immunityPrincipal Investigator

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Togashi Yosuke 冨樫庸介