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Yamashiro Keisuke  山城 圭介

… Alternative Names

YAMASHIRO KEISUKE  山城 圭介

YAMASHIRO Keisuke  山城 圭介

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Researcher Number 30581087
Other IDs
  • ORCIDhttps://orcid.org/0000-0003-1208-892X
Affiliation (Current) 2025: 神戸常盤大学, 保健科学部, 教授
Affiliation (based on the past Project Information) *help 2019 – 2022: 岡山大学, 大学病院, 講師
2021: 神戸常盤大学短期大学部, 口腔保健学科, 教授
2016 – 2018: 岡山大学, 医歯薬学総合研究科, 助教
2014: 岡山大学, 医歯薬学総合研究科, 助教
2011 – 2014: 岡山大学, 医歯(薬)学総合研究科, 助教
2013: 岡山大学, 大学院医歯薬学総合研究科, 助教
2010 – 2011: 岡山大学, 大学院・医歯薬学総合研究科, 助教
Review Section/Research Field
Principal Investigator
Periodontal dentistry / Basic Section 57030:Conservative dentistry-related / Periodontology
Except Principal Investigator
Periodontal dentistry / Basic Section 57030:Conservative dentistry-related
Keywords
Principal Investigator
マクロファージ / HMGB1 / 歯周病 / 炎症 / 細胞接着 / TGF-β / 歯肉上皮細胞 / 幹細胞 / 創傷治癒 / 低栄養 … More / 遺伝子 / 免疫学 / 歯学 / 抗体療法 / 炎症性サイトカイン / 歯周炎 / 好中球 / サイトカイン / 歯周組織再生 / ECM / integrin / 歯周病原細菌 / TGF-b / 感染 / 細胞増殖 / E-cadherin / Actinobacillus actinomycetemcomitans / フィブロネクチン / Aggregatibacter ac / 細胞外マトリックス / 細胞接着因子 / Aggregatibacter actinomycetemcomitans / Smad2 / 細胞外基質 / インテグリン … More
Except Principal Investigator
歯周組織 / lipid mediator / pulp capping / Dentin regeneration / Resolvin D2 (RVD2) / Dental pulp cells / Resolving D2 / Dental pulp cell / Reparative dentin / Resolvin D2 / Vital pulp therapy / 糖尿病 / IL-6 / 歯周炎 / 慢性炎症 / サルコペニア / 炎症性老化 / 歯周組織再生 / 幹細胞 / 微小環境 / 増殖因子 / 細胞外基質 / インテグリン / アンチセンス医療 / キャリアーペプチド / アンチセンス / ペプチド核酸 / 歯周病原細菌 / 歯周病 / 細胞増殖・分化 / 細胞周期 / 口内炎 / BP製剤 / 顎骨壊死 / 感染 / ストレスファイバー / Rho-kinase / Rho / ROCK / RhoA / 遺伝子発現 / 遺伝子導入 / Y-27632 / RhoA-ROCKシグナル / 細胞分化 / 歯根膜 Less
  • Research Projects

    (11 results)
  • Research Products

    (29 results)
  • Co-Researchers

    (23 People)
  •  APPLICATION OF RvD2 AS A REGENERATIVE DIRECT PULP CAPPING MATERIAL

    • Principal Investigator
      ARIAS MARTINEZ Zulema Rosalia
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57030:Conservative dentistry-related
    • Research Institution
      Okayama University
  •  Malnutrition delayed wound healing by HMGB1-related prolonged inflammationPrincipal Investigator

    • Principal Investigator
      Yamashiro Keisuke
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57030:Conservative dentistry-related
    • Research Institution
      Kobe Tokiwa Junior College
      Okayama University
  •  Investigation of integrin peptide therapy regulating stem cell niche for periodontal regeneration

    • Principal Investigator
      Yamamoto Tadashi
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57030:Conservative dentistry-related
    • Research Institution
      Okayama University
  •  Elucidation of pathology of periodontal disease, sarcopenia, and diabetes centered on inflammation-aging

    • Principal Investigator
      Kobayashi Hiroya
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57030:Conservative dentistry-related
    • Research Institution
      Okayama University
  •  Functional analysis of HMGB1 as an inflammatory mediator in periodontitisPrincipal Investigator

    • Principal Investigator
      YAMASHIRO KEISUKE
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Periodontology
    • Research Institution
      Okayama University
  •  Application of antisense PNA as antibiotics against periodontal pathogens

    • Principal Investigator
      MAEDA Hiroshi
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Periodontal dentistry
    • Research Institution
      Osaka Dental University
      Okayama University
  •  歯肉上皮細胞におけるTGF-βによる細胞接着因子制御の分子生物学的解明Principal Investigator

    • Principal Investigator
      山城 圭介
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Periodontal dentistry
    • Research Institution
      Okayama University
  •  Construction of the prevention system of a Bisphosphonate-Related Osteonecrosis of the Jaw judging from an intraoral infection degree

    • Principal Investigator
      HATANAKA KAZU
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Periodontal dentistry
    • Research Institution
      Okayama University
  •  Cell cycle atlas of periodontium

    • Principal Investigator
      YAMAMOTO Tadashi
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Periodontal dentistry
    • Research Institution
      Okayama University
  •  The molecular biological analysis of the mechanism for cell adhesion mediated by growth factor in human gingival epithelial cellsPrincipal Investigator

    • Principal Investigator
      YAMASHIRO Keisuke
    • Project Period (FY)
      2010 – 2011
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Research Field
      Periodontal dentistry
    • Research Institution
      Okayama University
  •  Investigation of the mechanisms of osteogenic differentiation by RhoA in periodontal ligament cells for cell transplantation

    • Principal Investigator
      YAMAMOTO Tadashi
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Periodontal dentistry
    • Research Institution
      Okayama University

All 2021 2020 2018 2017 2016 2014 2013 2012 2011 Other

All Journal Article Presentation

  • [Journal Article] Malnutrition delayed wound healing after tooth extraction by HMGB1-related prolonged inflammation2021

    • Author(s)
      Yao Zhang, Hidetaka Ideguchi, Hiroaki Aoyagi, Keisuke Yamashiro, Tadashi Yamamoto, Masahiro Nishibori, Shogo Takashiba
    • Journal Title

      Int Immunopharmacol

      Volume: 96 Pages: 107772-107772

    • DOI

      10.1016/j.intimp.2021.107772

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K10128, KAKENHI-PROJECT-19H03408, KAKENHI-PROJECT-20K23054
  • [Journal Article] Elucidation of the mechanism of prolonged inflammation and delayed wound healing during malnutrition: possible HMGB1 dysfunction2021

    • Author(s)
      Keisuke Yamashiro
    • Journal Title

      Impact

      Volume: 2021 Issue: 6 Pages: 26-26

    • DOI

      10.21820/23987073.2021.6.26

    • Open Access
    • Data Source
      KAKENHI-PROJECT-19K10128
  • [Journal Article] High Mobility Group Box 1 Expression in Oral Inflammation and Regeneration2020

    • Author(s)
      Keisuke Yamashiro, Hidetaka Ideguchi, Hiroaki Aoyagi, Chiaki Yoshihara-Hirata, Anna Hirai, Risa Suzuki-Kyoshima, Yao Zhang, Hidenori Wake, Masahiro Nishibori, Tadashi Yamamoto, ShogoTakashiba
    • Journal Title

      Frontiers in Immunology

      Volume: 11 Pages: 1461-1461

    • DOI

      10.3389/fimmu.2020.01461

    • NAID

      120006880201

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K10128, KAKENHI-PROJECT-20K23054
  • [Journal Article] Anti-HMGB1 Neutralizing Antibody Attenuates Periodontal Inflammation and Bone Resorption in a Murine Periodontitis Model2018

    • Author(s)
      Yoshihara-Hirata Chiaki、Yamashiro Keisuke、Yamamoto Tadashi、Aoyagi Hiroaki、Ideguchi Hidetaka、Kawamura Mari、Suzuki Risa、Ono Mitsuaki、Wake Hidenori、Nishibori Masahiro、Takashiba Shogo
    • Journal Title

      Infection and Immunity

      Volume: 86 Issue: 5

    • DOI

      10.1128/iai.00111-18

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H06994, KAKENHI-PROJECT-16K20670, KAKENHI-PROJECT-18K17050, KAKENHI-PROJECT-16K11624
  • [Journal Article] HMGB1-induced inflammatory response promotes bone healing in murine tooth extraction socket2018

    • Author(s)
      Aoyagi Hiroaki、Yamashiro Keisuke、Hirata-Yoshihara Chiaki、Ideguchi Hidetaka、Yamasaki Mutsuyo、Kawamura Mari、Yamamoto Tadashi、Kochi Shinsuke、Wake Hidenori、Nishibori Masahiro、Takashiba Shogo
    • Journal Title

      Journal of Cellular Biochemistry

      Volume: - Issue: 7 Pages: 5481-5490

    • DOI

      10.1002/jcb.26710

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H06994, KAKENHI-PROJECT-16K20670, KAKENHI-PROJECT-18K17050
  • [Journal Article] Overexpression of Smad2 Inhibits Proliferation of Gingival Epithelial Cells2014

    • Author(s)
      Shimoe M, Yamamoto T, Shiomi N, Tomikawa K, Hongo S, Yamashiro K, Yamaguchi T, Maeda H, Takashiba S
    • Journal Title

      J Periodontal Res

      Volume: 49(3) Issue: 3 Pages: 290-8

    • DOI

      10.1111/jre.12106

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659977
  • [Journal Article] Overexpression of Smad2 Inhibits Proliferation of Gingival Epithelial Cells2013

    • Author(s)
      Masayuki Shimoe, Tadashi Yamamoto, Nobuyuki Shiomi, Kazuya Tomikawa, Shoichi Hongo, Keisuke Yamashiro, Tomoko Yamaguchi, Hiroshi Maeda, Shogo Takashiba
    • Journal Title

      Journal of periodontal research

      Volume: 未定

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24792327
  • [Journal Article] Smad2 decekerates re-epithelialization during gingival wound healing.2012

    • Author(s)
      Tomikawa Kazuya
    • Journal Title

      journal of dentak research

      Volume: 91 Issue: 8 Pages: 764-770

    • DOI

      10.1177/0022034512451449

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23890128, KAKENHI-PROJECT-24792327
  • [Presentation] Resolvin D2 Promotes the Formation of Calcified Tissue on Pulp2021

    • Author(s)
      Mitsuhiro Yoneda, Zulema Rosalia Arias Martinez, Shin Nakamura, Kentaro Okamoto, Masahiro Ito, Kazuya Tamura, Hidetaka Ideguchi, Kazuhiro Omori, Keisuke Yamashiro, Tadashi Yamamoto, Shogo Takashiba.
    • Organizer
      2021 IADR/ AADR/ CADR General Session
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K09938
  • [Presentation] Delayed Wound Healing after Tooth Extraction under Malnutrition2020

    • Author(s)
      Y. ZHANG, H. IDEGUCHI, H. AOYAGI, K. YAMASHIRO, T. YAMAMOTO, M. NISHIBORI, S. TAKASHIBA
    • Organizer
      Japanese Association for Dental Research
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K10128
  • [Presentation] インテグリンα3の選択的阻害による微小環境の構築と歯槽骨再生2020

    • Author(s)
      森彩乃,山本直史,河村麻理,井手口英隆,青柳浩明,中村心,岡本憲太郎,平井杏奈,山城圭介,大森一弘,高柴正悟
    • Organizer
      日本歯科保存学会
    • Data Source
      KAKENHI-PROJECT-18K09576
  • [Presentation] 炎症性メディエーターHMGB1が歯槽骨治癒における血管新生の遺伝子発現を促進する2017

    • Author(s)
      青柳浩明,山城圭介,吉原千暁,井手口英隆,山本直史,河村麻理,下江正幸,本郷昌一,劉克約,西堀正洋,高柴正悟
    • Organizer
      第38回炎症再生医学会
    • Data Source
      KAKENHI-PROJECT-16K20670
  • [Presentation] HMGB1が歯槽骨治癒に及ぼす影響2017

    • Author(s)
      青柳浩明,山城圭介,吉原千暁,井手口英隆,山本直史,河村麻理,下江正幸,高柴正悟
    • Organizer
      第60回日本歯周病学会
    • Data Source
      KAKENHI-PROJECT-16K20670
  • [Presentation] 実験的歯周炎モデルマウスにおける抗HMGB1抗体の歯周炎抑制効果2016

    • Author(s)
      吉原千暁,山城圭介,山本直史,井手口英隆,青柳浩明,下江正幸,本郷昌一,河村麻理,高柴正悟
    • Organizer
      第59回春季日本歯周病学会
    • Place of Presentation
      かごしま県民交流センター,鹿児島市
    • Year and Date
      2016-05-21
    • Data Source
      KAKENHI-PROJECT-16K20670
  • [Presentation] Anti-HMGB1 neutralizing antibody attenuates cytokine secretion and progression of periodontitis2016

    • Author(s)
      C. YOSHIHARA,K. YAMASHIRO,T. YAMAMOTO,H. IDEGUCHI,H. AOYAGI,M. SHIMOE,S. HONGO,M. KAWAMURA,K. Liu,M. NISHIBORI,S. TAKASHIBA,
    • Organizer
      IADR/APR General Session & Exhibition
    • Place of Presentation
      COEX Convention Center, Korea, Seoul
    • Year and Date
      2016-06-22
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K20670
  • [Presentation] グリチルリチン酸 経口投与によるin vivo 歯周組織治癒効果2014

    • Author(s)
      井手口英隆,山城圭介,山本直史,本郷昌,下江正幸,高知信介,青柳浩明,吉原千暁,河村麻里,前田博史,高柴正悟
    • Organizer
      第57回日本歯周病学会春季学術大会
    • Place of Presentation
      岐阜
    • Year and Date
      2014-05-23
    • Data Source
      KAKENHI-PROJECT-23659977
  • [Presentation] グリチルリチン酸 経口投与によるin vivo歯周組織治癒効果2014

    • Author(s)
      井手口英隆,山城圭介,山本直史,本郷昌一,下江正幸,高知信介,青柳浩明,吉原千暁,河村麻里,前田博史,高柴正悟
    • Organizer
      第57回日本歯周病学会春季学術大会
    • Place of Presentation
      岐阜
    • Data Source
      KAKENHI-PROJECT-23659977
  • [Presentation] 外来化学療法中の患者における口内炎発症の実態と今後の課題について2013

    • Author(s)
      高坂由紀奈、杉浦裕子、小倉早紀、三浦留美、山城圭介、宮脇卓也、田端雅弘
    • Organizer
      岡山歯学会総会・学術集会
    • Place of Presentation
      岡山市
    • Year and Date
      2013-10-27
    • Data Source
      KAKENHI-PROJECT-23593058
  • [Presentation] 外来化学療法中の患者における口内炎発症の実態と今後の課題について2013

    • Author(s)
      高坂由紀奈,杉浦裕子,小倉早妃,三浦留美,山城圭介,宮脇卓也,田端雅弘
    • Organizer
      岡山歯学会
    • Place of Presentation
      岡山市
    • Data Source
      KAKENHI-PROJECT-23593058
  • [Presentation] 歯肉上皮においてSmad2はintegrin発現を促進する2013

    • Author(s)
      本郷昌一,山城圭介,山本直史,高知信介,下江正幸, 冨川和哉,鵜川祐樹,前田博史,高柴正悟
    • Organizer
      138回 日本歯科保存学会
    • Place of Presentation
      博多市
    • Data Source
      KAKENHI-PROJECT-24792327
  • [Presentation] Aggregatibacter actinomycetemcomitans Y4はintegrin α5を介して細胞内に侵入する2013

    • Author(s)
      高知信介,山城圭介,山本直史,下江正幸,本郷昌一,冨川和哉,鵜川祐樹,前田博史 ,高柴正悟
    • Organizer
      第56回秋季日本歯周病学会
    • Place of Presentation
      前橋市
    • Data Source
      KAKENHI-PROJECT-24792327
  • [Presentation] 歯肉上皮細胞において外因性Smad2は細胞接着分子の発現を促進する2011

    • Author(s)
      本郷昌一, 山城圭介
    • Organizer
      第54回秋季日本歯周病学会
    • Place of Presentation
      山口県下関市
    • Year and Date
      2011-09-23
    • Data Source
      KAKENHI-PROJECT-22890119
  • [Presentation] Aggregatibacter actinomycetemcomitansがヒト歯肉上皮細胞の細胞接着因子に及ぼす影響2011

    • Author(s)
      高知信介, 山城圭介
    • Organizer
      平成23年度秋季日本歯科保存学会
    • Place of Presentation
      大阪府大阪市
    • Year and Date
      2011-10-21
    • Data Source
      KAKENHI-PROJECT-22890119
  • [Presentation] 歯根膜線維芽細胞においてSmad2はFGF2遺伝子発現を促進する

    • Author(s)
      鵜川祐樹,山本直史,山城圭介,下江正幸,冨川和哉,本郷昌一,高知信介,前田博史,高柴正悟
    • Organizer
      第137回日本歯科保存学会秋季大会
    • Place of Presentation
      広島県広島市
    • Data Source
      KAKENHI-PROJECT-24792327
  • [Presentation] Integrin α5 Regulates Cell Adhesion in Gingival Epithelium during Infection

    • Author(s)
      S. KOCHI, K. YAMASHIRO, T. YAMAMOTO, S. HONGO, M. SHIMOE, K. TOMIKAWA, Y. UGAWA, H. MAEDA, S. TAKASHIBA
    • Organizer
      91th International Association for Dental Research
    • Place of Presentation
      Seattle, USA
    • Data Source
      KAKENHI-PROJECT-24792327
  • [Presentation] Overexpression of Smad2 Enhances FGF2 Expression in Periodontal Ligament Cells

    • Author(s)
      Y. UGAWA, T. YAMAMOTO, K. YAMASHIRO, S. HONGO, H. IDEGUCHI, M. SHIMOE, K. TOMIKAWA, S. KOCHI, H. MAEDA, S. TAKASHIBA
    • Organizer
      91th International Association for Dental Research
    • Place of Presentation
      Seattle, USA
    • Data Source
      KAKENHI-PROJECT-24792327
  • [Presentation] Aggregatibacter actinomycetemcomitansおよび抗菌薬添加がヒト歯肉上皮細胞の細胞接着因子に及ぼす影響

    • Author(s)
      高知信介,山城圭介, 山本直史,本郷昌一, 下江正幸,冨川和哉,鵜川祐樹,前田博史,高柴正悟
    • Organizer
      第136回日本歯科保存学会春季大会
    • Place of Presentation
      沖縄県宜野湾市
    • Data Source
      KAKENHI-PROJECT-24792327
  • [Presentation] 歯肉上皮細胞においてSmad2/3は細胞接着分子と細胞外基質の発現を促進する

    • Author(s)
      本郷昌一,山城圭介,山本直史,高知信介,下江正幸,冨川和哉,鵜川祐樹,前田博史,高柴正悟
    • Organizer
      第55回日本歯周病学会春季学術大会
    • Place of Presentation
      北海道札幌市
    • Data Source
      KAKENHI-PROJECT-24792327
  • [Presentation] TGF-β Signaling Enhances Cell Adhesion in Gingival Epithelial Cells

    • Author(s)
      S. Hongo, K. Yamashiro, T. Yamamoto, S. Kochi, M. Shimoe, K. Tomikawa, Y. Ugawa, H. Maeda, S. Takashiba
    • Organizer
      91th International Association for Dental Research
    • Place of Presentation
      Seattle, USA
    • Data Source
      KAKENHI-PROJECT-24792327
  • 1.  TAKASHIBA Shogo (50226768)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 9 results
  • 2.  YAMAMOTO Tadashi (50432662)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 8 results
  • 3.  HATANAKA KAZU (50362992)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  AOYAGI Hiroaki (10814501)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 7 results
  • 5.  NISHIBORI Masahiro (50135943)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 5 results
  • 6.  Kobayashi Hiroya (20710651)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  MINESHIBA Junji (00509383)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  NARUISHI Koji (00346446)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  SHIOMI Nobuyuki (90432632)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  SONOYAMA Wataru (40325121)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
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  • 19.  ARIAS MARTINEZ Zulema Rosalia (70824580)
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  • 20.  宝田 剛志 (30377428)
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  • 21.  大森 一弘 (20549860)
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  • 22.  ISOSHIMA Daichi
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  • 23.  TOMIKAWA Kazuya
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