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Nakauchi Hiromitsu  中内 啓光

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NAKAUCHI Hiromitsu  中内 啓光

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Researcher Number 40175485
External Links
Affiliation (Current) 2025: 東京科学大学, 総合研究院, 特任教授
Affiliation (based on the past Project Information) *help 2022 – 2024: 東京医科歯科大学, 高等研究院, 特別栄誉教授
2020 – 2021: 東京大学, 医科学研究所, 特任教授
2017 – 2018: 東京大学, 医科学研究所, 特任教授
2002 – 2016: Yokohama City University, Laboratory of Stem Cell Therapy, Center for Experimental Medicine, Institute of Medical Science, University of Tokyo, 医科学研究所, 教授
2008: The University of Tokyo, 医化学研究所, 教授 … More
2005: 東大, 医科学研究所, 教授
1994 – 2001: Univ.of Tsukuba Dept.of Immunology, Professor, 基礎医学系, 教授
1997 – 1998: 筑波大学, 医学部, 教授
1994 – 1995: 筑波大学, 医学部, 教授
1993: 筑波大学, 基礎医学系・免疫学, 教授
1992 – 1993: 理化学研究所, 造血制御研究チーム, チームリーダー
1990 – 1992: 理科学研究所, 研究員
1991: The Inst. of Physic. and Chem. Res., Researcher, 国際フロンティア研究システム クロモゾーム研究チーム, 研究員
1991: 理化学研究所, 国際フロンティア研究システム・クロモゾーム研究チーム, 研究員
1990 – 1991: 理化学研究所, フロンティア研究システム, 研究員
1987 – 1988: 順天堂大学, 医学部, 講師
1987 – 1988: 順天堂大学, 医学部, 非常勤講師
1986: 順天堂大学, 医学部, 助手
1986: 順天堂大学, 医学部・免疫学研究室, 助手 Less
Review Section/Research Field
Principal Investigator
Hematology / Hematology / Biological Sciences / Immunology / General medical chemistry / General surgery / Medium-sized Section 54:Internal medicine of the bio-information integration and related fields / Broad Section I / Embryonic/Neonatal medicine / 内科学一般 / Science and Engineering … More
Except Principal Investigator
… More General surgery / Biological Sciences / Immunology / Virology / Kidney internal medicine / Hematology / 内分泌・代謝学 / Science and Engineering / Hematology Less
Keywords
Principal Investigator
造血幹細胞 / CD34 / サイトカイン / IL-3 / 骨髄移植 / 自己複製 / 免疫寛容 / HIV / hematopoietic stem cells / 自己複製能 … More / GM-CSF / CD8 / NK細胞 / 骨髄ニッチ / SP細胞 / 可塑性 / 骨髄微小環境 / トランスジェニックマウス / 骨髄キメラ / CD4 / 血液幹細胞 / 体外増幅 / 発癌 / 加齢 / Lyt-3 / Lyt-2 / self-renewal / DNAM-1 / LFA-1 / コミットメント / NKT cells / granuloma / NKT細胞 / 肉芽腫 / G-CSF / NK cells / Hematopoietic stem cells / SCF / IL-2 / Stem Cell Factor / CD33 / 冬眠 / 非対称性分裂 / bcrp-1 / ES細胞 / ホーミング / ニッシェ / 多分化能 / 幹細胞 / 遺伝子治療 / Fas / Mel-14 / リンパ球系幹細胞 / マクロファージ指向性 / T細胞指向性 / HIVベクター / 肝幹細胞 / 肝移植 / clonal anergy / clonal deletion / アポトーシス / マルチオミックス解析 / 遺伝子ノックアウトスクリーニング / クローン性造血 / CRISPRgRNAスクリーニング / クローナル造血 / ex vivo増幅 / 培地 / 造血幹細胞移植学 / 骨髄環境 / アミノ酸バランス / BCAA / バリン / アミノ酸 / MHC class 1 / 免疫グロブリン多重遺伝子族 / alternative splicing / MHCクラス1 / Lyt-3-alternative splicing / MHC7ラス11 / commitment / DNA methylation / asymmetric division / Dnmt3b / Dnmt3a / DNAメチル化酵素 / DNAメチル化 / plasticity / ABCG2 / ABC transporter / Gfi-1B / アダプター分子 / lnk / 血管内皮前駆細胞 / 造血肝細胞 / Fc receptor / adhesion molecule / inhibitory receptor / Mycobacterium / Fc受容体 / FC受容体 / 接着分子 / 活性化抑制性レセプター / 活性化レセプター / microchimerism / retroviralvector / crab-eatingmonkey / in utero gene therapy / in utero transplantation / 異種移植 / 遺伝子導入 / サル / 子宮内胎児細胞移植 / レトロウィルスベクター / カニクイザル / レトロウイルスベクター / 胎児遺伝子治療 / 子宮内細胞移植 / lineage commitment / cell cycle / hematopoietic Progenitor cells / hematopoietic stem cell / 長期骨髄再建能 / seeding efficiency / Stochastic model / paired-daughter cells / 末梢血幹細胞移植 / mobilization / 細胞周期 / 造血前駆細胞 / positive selection / MEL-14 / lymphoid committed progenitors / T cell differentiation / IL-7受容体 / 器官培養 / 胸腺内分化 / 正の選択 / Met-14 / リンパ球糸幹細胞 / T細胞分化 / NK cells. / Myelodysplastic syndrome / SCID mice / transgenic mice / swine / GM- CSF / MDS / ブタ / SCIDマウス / stroma cells / stem cell factor / NK前駆細胞 / ストローマ細胞 / bone marrow transplantation / diabetes / cytokines / somatic cell gene therapy / アガロース / インシュリン / c-kit / 多能性 / 糖尿病 / 体細胞遺伝子治療 / 休眠状態 / TGF-beta / ガン / 血小板 / 赤芽球 / 末梢循環がん細胞 / 閉鎖系高速細胞解析分離装置 / 医工学融合 / 閉鎖系 / がん / デバイス / 微小細胞 / T細胞の分化誘導 / iPS細胞 / 抗原特異的T細胞 / smad signaling / 冬眠機構 / TGFβ / 脂質ラフト / FOXO転写因子 / 白血病幹細胞 / GFAP陽性細胞 / 非髄鞘シュワン細胞 / CD34陽性細胞 / Sall 1 / 賢臓 / ES cells / blastcyst complementation / 臓器再生 / 膵臓 / 固型臓器再生 / リピッドラフト / ニッチシグナル / TGF-β / FOXO / ニッチ / リッピドラフト / 活性型STAT / blastcyst / 対娘細胞解析 / ポリコーム遺伝子群 / Competitive Repopulation Unit / Repopulation Unit / 精子幹細胞 / Bmi-1 / ポリコーム群タンパク / myeloproliferative disorder / TMTSP / STAT5 / Endomucin / Lnk / 末分化性維持機構 / 造的幹細胞 / ポリコーム遺伝子産物 / ATM / 未分化性 / テクノロジー / 再生医療 / 未分化性維持機構 / 細胞内抗体 / CCR5 / ベクター / レンチウイルス / エイズ / 免疫遺伝子治療 / AP20187 / FKBP12 / HSV-TK / 自殺遺伝子 / FK506 / DLT / GVT / GVL / GVHD / ミクロキメリズム / 異所性骨髄形成 / BMP / FACS / L-Selectin / リンパ球系前駆細胞 / ケモカインレセプター / マウスモデル / HIV感染 / 移植免疫 / 自己寛容 / キメリズム / 肝臓 / bcl-2 / 脾臓 / 肝臓移植 / 肝細胞 / β-gal / マクロファージ指向性HIV / ネオマイシン耐性遺伝子 / lac-Z / FDG(Fluorescein β-D-galactopyranoside) / Scaー1 / cーkit / エリスロポエチン受容体 / エリスロポエチンレセプタ- / Cーkit / 巨核芽球 / エリスロポエチン リセプタ- … More
Except Principal Investigator
再生医学 / 幹細胞 / 再生 / 肝臓 / 造血幹細胞 / 再生医療 / 遺伝子治療 / 分化 / CD2 / CD8 / LFA / HTLV-I / レセプター / HTLV-1 / エンベロープ / differentiation / 転写因子 / GATA / CD34 / 糖尿病 / トランスジェニックマウス / 細胞分化 / 癌 / 免疫学 / トランスレーショナルリサーチ / ウイルス / ES細胞 / C / AGM領域 / 受容体型チロシンキナーゼ / IL-6 / 自己複製能 / マウスモデル / CD4 / 包括的DNAメチル化解析 / 腎臓再生 / iPS細胞移植 / エピジェネティックス / HDAC阻害剤 / 腎臓細胞記憶 / DNAメチル化解析 / Epigenetics / 新規腎臓発生・再生因子 / 網羅的マイクロアレイ解析 / 包括的メチル化解析 / 腎系統特異的分化誘導法 / 腎臓由来iPS細胞 / Epigenetic Memory / Monoclonal Antibody / Ts / T細胞機能分子 / T細胞レセプター / サプレッサーT細胞 / DNAクローニング / FACS / トランスフェクタント / リンパ球機能分子 / CD2遺伝子 / CD8遺伝子 / トランスフェクション / パーフォリン / モノクローナル抗体 / TS / Diabetes / Stem Cell / Regeneration / Pancreas / 膵臓 / platelet transfusion / in vitro induced platelets / megakaryopoiesis / 血小板輸血 / 培養血小板 / 巨核球造血の増幅 / cytokines / cell growth / サイトカイン / 細胞増殖 / Stem cell / Liver / Regenerative Medicine / Transgenic mouse / Integration / Mouse lymphocytes / Receptor / HTLV-I 感染 / HTLV-l / 組み込み / マウスリンパ球 / レセプター分子 / HIV-vector / Envelope / Tropism / Retrovirus / パッケージング / Pseudotype / 組換えレトロウイルス / レトロウィルス / HIVベクター / HTLV・I / トロピズム / レトロウイルス / positive selection / stromal cell / progenitor / hematopoietic stem cell / transcription factor / T cell / thymus / 正・負の選択 / 増殖因子 / 胸腺ストローマ細胞 / 骨髄 / 生長因子 / 決定 / 正の選択 / ストローマ細胞 / 前駆細胞 / T細胞 / 胸腺 / IL-6R / receptor tyroshine kinases / hemotopoietic stem cells / 幹細胞増幅 / 蛍光細胞分離装置 / gp130 / 赤血球分化 / 転写調節 / 多分化能 / 細胞運命決定因子 / 血液幹細胞 / シグナル伝達 / 造血前駆細胞 / IL-6可溶性受容体 / immune complex / PI-anchor / chimeric protein / chimeric gene / complement receptor / 免疫複合体病 / CR1 / DAF / PCR / PIアンカ- / 補体レセプタ- / PIアンカー / 免疫複合体 / 補体レセプター / キメラ遺伝子 / キメラ蛋白 / transkaryotic / monoclonal antibody / differentiation antigen / metallothionein / proinsulin / fibrablasts / diabetes mellitus / gene therapy / モノクロ-ナル抗体 / 表面抗原 / メタロチオネインプロモ-タ- / プロインスリン / 線維芽細胞 / トランスカリョ-ティック法 / 免疫グロブリン遺伝子 / T細胞レセプター遺伝子 / クローナリティー / 分化抗原 / ホーミング / リンパ球の分化 / リンパ腫 / マイクロアレイ / iPS細胞 / メチル化 / iPS cells / マイクロナノロボテックス / 幹細胞生物学 / メカトロニクス / マイクロナノロボティクス / バイオアセンブラ / マイクロロボティクス / 増殖 / 増殖と分化 / IL-27 / 分化誘導 / PU.1 / EBP / 樹状細胞 / ランゲルハンス細胞 / 胚性幹細胞 / 遺伝子変異 / 好中球分化 / EBPα / 急性骨髄性白血病 / フローサイトメトリー / 精子 / GFP / 遺伝子導入マウス / 自己修復能 / リンパ球 / DNAM-1 / LFA-1 / 接着分子 / 自己複製型因子 / 新規ケモカイン / 血管新生 / 血管内皮細胞 / 受容体型チコシンキナーゼ / 対外増幅 / 転写制御 / Hemagioblast / CD34分子 / ヒト造血幹細胞アッセイ系 / ヒト細胞移植系 / 骨髄移植療法 / 血管新生因子 / -マウス / AML-1- / VEカドヘリン / Hemangioblast / AGM細胞 / 分化制御 / 臍帯血造血幹細胞 / 可溶性IL-6受容体 / 未分化性維持 / 血管新生療法 / 造血幹細胞移植 / ケモカインレセプター / HIV感染 / アポトーシス / 細胞内領域欠損型 / 受容体 / エリスロポエチン / 赤血球 / 骨髄キメラ / clonal anergy / clonal deletion / 免疫寛容 / 骨髄移植 / LTR / FDG(Fluorescein beta-D-galactopyranoside) / HIV Less
  • Research Projects

    (71 results)
  • Research Products

    (438 results)
  • Co-Researchers

    (127 People)
  •  Analysis of stemness, aging and carcinogenesis using hematopoietic stem cell ex vivo amplification systemPrincipal Investigator

    • Principal Investigator
      中内 啓光
    • Project Period (FY)
      2020 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Review Section
      Broad Section I
    • Research Institution
      Tokyo Medical and Dental University
      The University of Tokyo
  •  マウス造血幹細胞体外増幅系を用いた幹細胞性・加齢・発癌機構の解析Principal Investigator

    • Principal Investigator
      中内 啓光
    • Project Period (FY)
      2020
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 54:Internal medicine of the bio-information integration and related fields
    • Research Institution
      The University of Tokyo
  •  Hematopoietic stem cell control by amino acids and development of novel therapeutic methodsPrincipal Investigator

    • Principal Investigator
      Hiromitsu Nakauchi
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Hematology
    • Research Institution
      The University of Tokyo
  •  Establishment of a specific differentiation induction method to the kidneys constituent cells using a cell memory of the human kidney-derived iPS cells

    • Principal Investigator
      TAKASE OSAMU
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      The University of Tokyo
  •  Identification of human bone marrow niche to support HSCsPrincipal Investigator

    • Principal Investigator
      NAKAUCHI Hiromitsu
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Hematology
    • Research Institution
      The University of Tokyo
  •  Research Management

    • Principal Investigator
      Arai Tatsuo
    • Project Period (FY)
      2011 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Science and Engineering
    • Research Institution
      Osaka University
  •  Development of high-speed closed system for analysis and isolation of rare cell populations within the bloodPrincipal Investigator

    • Principal Investigator
      nakauchi hiromitsu
    • Project Period (FY)
      2011 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Science and Engineering
    • Research Institution
      The University of Tokyo
  •  Artifical kidney established by human kidney derived iPS cells

    • Principal Investigator
      HISHIKAWA Keiichi
    • Project Period (FY)
      2011 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      The University of Tokyo
  •  Development of novel immunotherapy by using of human iPS cells of an antigen-specific T-cell originPrincipal Investigator

    • Principal Investigator
      NAKAUCI Hiromitsu
    • Project Period (FY)
      2010 – 2011
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      General medical chemistry
    • Research Institution
      The University of Tokyo
  •  Elucidation of the mechanisms underlying maintenance of hematopoietic stem cell hibernationPrincipal Investigator

    • Principal Investigator
      NAKAUCHI Hiromitsu
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Hematology
    • Research Institution
      The University of Tokyo
  •  Identification of niche signal prescribing hibernation of hematopoietic stem cellPrincipal Investigator

    • Principal Investigator
      NAKAUCHI Hiromitsu
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Hematology
    • Research Institution
      The University of Tokyo
  •  発生工学的手法を用いた固型臓器再生の試みPrincipal Investigator

    • Principal Investigator
      中内 啓光
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      General medical chemistry
    • Research Institution
      The University of Tokyo
  •  新しいIL-6/12関連サイトカインIL-27による造血幹細胞の増殖・分化の制御

    • Principal Investigator
      善本 隆之
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Hematology
    • Research Institution
      Tokyo Medical University
  •  Molecular basis of asymmetric division and lineage commitment in hematopoietic stem cellsPrincipal Investigator

    • Principal Investigator
      NAKAUCHI Hiromitsu
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Hematology
    • Research Institution
      The University of Tokyo
  •  レトロウイルスベクターを用いた養子免疫遺伝子細胞療法の確立

    • Principal Investigator
      小野寺 雅史
    • Project Period (FY)
      2003
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      University of Tsukuba
  •  レトロウイルスベクターを用いた養子免疫遺伝子細胞療法の確立

    • Principal Investigator
      ONODERA Masahumi
    • Project Period (FY)
      2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      University of Tsukuba
  •  幹細胞の可塑性と未分化性維持機構Principal Investigator

    • Principal Investigator
      中内 啓光
    • Project Period (FY)
      2002 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  骨髄幹細胞の可塑性とそのメカニズムPrincipal Investigator

    • Principal Investigator
      中内 啓光
    • Project Period (FY)
      2002 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  造血幹細胞をニッシェに導くホーミングレセプターのクローニングPrincipal Investigator

    • Principal Investigator
      中内 啓光
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Hematology
    • Research Institution
      The University of Tokyo
  •  胚性幹(ES)細胞の分化制御による再生医療に関する基礎的研究

    • Principal Investigator
      谷口 英樹
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      General surgery
    • Research Institution
      Yokohama City University
  •  Stem cell regulation for the differenntiiation of insulin-produucing cells

    • Principal Investigator
      TANIGUCHI Hideki
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      General surgery
    • Research Institution
      Yokohama City University
  •  レンチウイルスベクターによるHIV感染症の遺伝子治療Principal Investigator

    • Principal Investigator
      中内 啓光
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Review Section
      Biological Sciences
    • Research Institution
      University of Tsukuba
  •  転写調節因子による骨髄球系樹状細胞の分化と機能制御

    • Principal Investigator
      岩間 厚志
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
      University of Tsukuba
  •  外科領域における再生医学に関する基盤的研究

    • Principal Investigator
      深尾 立
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      General surgery
    • Research Institution
      University of Tsukuba
  •  Plasticity and diversity of hematopoietic stem cellsPrincipal Investigator

    • Principal Investigator
      NAKAUCHI Hiromitsu
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Hematology
    • Research Institution
      THE UNIVERSITY OF TOKYO
      University of Tsukuba
  •  精子および卵子の標識による効率的な複数遺伝子変異マウスの作成法の開発

    • Principal Investigator
      八神 健一
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      University of Tsukuba
  •  急性骨髄性白血病の病態形成における転写因子C/EBPαの遺伝子変異の生物学的意義

    • Principal Investigator
      IWAMA Atsushi
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      University of Tsukuba
  •  薬剤誘導性アポトーシス関連遺伝子用いた養子細胞免疫遺伝子治療の基礎的研究Principal Investigator

    • Principal Investigator
      中内 啓光
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      University of Tsukuba
  •  胚性幹細胞(ES細胞)の分化誘導による肝臓再構築に関する基礎的研究

    • Principal Investigator
      谷口 英樹
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      General surgery
    • Research Institution
      University of Tsukuba
  •  Identification and characterization of pluripotent hepatic stem cells in the liver

    • Principal Investigator
      TANIGUCHI Hideki
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      General surgery
    • Research Institution
      University of Tsukuba
  •  Role for growth factors and extracellular matrixes in controlling hepatic stem cell differentiation

    • Principal Investigator
      TANIGUCHI Hideki
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General surgery
    • Research Institution
      Yokohama City University
      University of Tsukuba
  •  Selective induction of megakaryocytes and functional analysis of in vitro induced-platelets (IVIP) derived from murine hematopoietic stem cells

    • Principal Investigator
      NAGASAWA Toshiro
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      University of Tsukuba
  •  血液系腫瘍に発現するβ_2インテグリン/DNAM-1複合体のシグナル伝達機構の解析

    • Principal Investigator
      SHIBUYA Akira
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      University of Tsukuba
  •  Graft vs Host反応を利用した新しいガン治療法開発の試みPrincipal Investigator

    • Principal Investigator
      中内 啓光
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      General surgery
    • Research Institution
      University of Tsukuba
  •  肝臓を標的とした「臓器再生」に向けた基礎的研究

    • Principal Investigator
      深尾 立
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      General surgery
    • Research Institution
      University of Tsukuba
  •  Establishment of in utero cell iransplantation and fetal gene therapy model using non-human primatePrincipal Investigator

    • Principal Investigator
      NAKAUCHI Hiromitsu
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Embryonic/Neonatal medicine
    • Research Institution
      Univ. of Tsukuba
  •  Mechanisms for differentiation and selection of T, NKT and NK cellsPrincipal Investigator

    • Principal Investigator
      NAKAUCHI Hiromistu
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Immunology
    • Research Institution
      Institute of Basic Medical Sciences, University of Tsukuba
  •  マウスモデルによるHIV感染ならびに発症機構の解析

    • Principal Investigator
      小糸 厚
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Review Section
      Biological Sciences
    • Research Institution
      University of Tsukuba
  •  造血幹細胞の発生と自己複製

    • Principal Investigator
      SUDA Toshio
    • Project Period (FY)
      1998 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Review Section
      Biological Sciences
    • Research Institution
      Kumamoto University
  •  Study of Generated trasgenic mice predominantly expressing T-tropic HIV-1

    • Principal Investigator
      KOITO Atsushi
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Virology
    • Research Institution
      Kumamoto University
      University of Tsukuba
  •  動物モデルによるHIV感染ならびに発症機構の解析Principal Investigator

    • Principal Investigator
      中内 啓光
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      University of Tsukuba
  •  造血幹細胞からリンパ球系への分化の分子機構Principal Investigator

    • Principal Investigator
      中内 啓光
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      University of Tsukuba
  •  BMPによる異所性骨髄形成を利用した骨髄ミクロキメリズムの誘導Principal Investigator

    • Principal Investigator
      中内 啓光
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Hematology
    • Research Institution
      University of Tsukuba
  •  ヒト造血系の動物モデルを利用したHIV感染ならびに発症機構の解析Principal Investigator

    • Principal Investigator
      中内 啓光
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      University of Tsukuba
  •  造血幹細胞からリンパ球系への分化の分子機構Principal Investigator

    • Principal Investigator
      中内 啓光
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      University of Tsukuba
  •  肝臓内造血幹細胞の同定と肝移植後のキメリズム誘導機序の検討Principal Investigator

    • Principal Investigator
      中内 啓光
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      General surgery
    • Research Institution
      University of Tsukuba
  •  Molecular mechanism of T cell differentiationPrincipal Investigator

    • Principal Investigator
      NAKAUCHI Hiromitsu
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Field
      Immunology
    • Research Institution
      Institute of Basic Medical Sciences, Univ of Tsukuba
  •  Characterization of the hematopoietic stem cell and search for the molecules responsible for stem cell self-renewal.Principal Investigator

    • Principal Investigator
      NAKAUCHI Hiromitsu
    • Project Period (FY)
      1996 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Hematology
    • Research Institution
      University of Tsukuba
  •  骨髄ミクロキメリズムによる抗原特異的免疫寛容の導入Principal Investigator

    • Principal Investigator
      中内 啓光
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      University of Tsukuba
  •  赤血球産生調節機構における細胞内領域欠損型エリスロポエチン受容体の機能解析

    • Principal Investigator
      中村 幸夫
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      University of Tsukuba
  •  肝幹細胞の同定とそれを標的とした遺伝子治療のための基礎的研究Principal Investigator

    • Principal Investigator
      中内 啓光
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      University of Tsukuba
  •  ヒト造血系の動物モデルを利用したHIV感染ならびに発症機構の解析Principal Investigator

    • Principal Investigator
      中内 啓光
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      University of Tsukuba
  •  Studies on the mechanism of T cell development in the thymus

    • Principal Investigator
      KATSURA Yoshimoto
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Immunology
    • Research Institution
      KYOTO UNIVERSITY
  •  Expansion of human hematopoiteic stem cells in transgenic or large animals.Principal Investigator

    • Principal Investigator
      NAKAUCHI Hiromitsu
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Hematology
    • Research Institution
      University of Tsukuba
  •  Approach to identify cellular factor(s) which determine spieces-and tissue-specificity of HTLV-infection

    • Principal Investigator
      KOITO Atsushi
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Virology
    • Research Institution
      Institute of Basic Medical Science, Tsukuba University
  •  HIV感染成立に必要なCD4以外の分子クローニングPrincipal Investigator

    • Principal Investigator
      中内 啓光
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      University of Tsukuba
  •  骨髄ミクロキメリズムによる抗原特異的免疫寛容の導入Principal Investigator

    • Principal Investigator
      中内 啓光
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      University of Tsukuba
  •  Purification and ampliefication of hematopoietic stem cells

    • Principal Investigator
      SUDA Toshio
    • Project Period (FY)
      1994 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kumamoto University
  •  HIV感染の成立に必要なCD4以外の分子のクローニング

    • Principal Investigator
      中村 幸夫
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The Institute of Physical and Chemical Research
  •  骨髄ミクロキメリズムによる抗原特異的免疫寛容の導入

    • Principal Investigator
      中村 幸夫
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The Institute of Physical and Chemical Research
  •  造血幹細胞に発現されている細胞表面機能分子の分子生物学的解析Principal Investigator

    • Principal Investigator
      中内 啓光
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The Institute of Physical and Chemical Research
  •  HIV感染の成立に必要なCD4以外の分子のクローニングPrincipal Investigator

    • Principal Investigator
      中内 啓光
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The Institute of Physical and Chemical Research
  •  Development of a model system for somatic cell gene therapy using hematopoietic stem cells and lymphoid cells.Principal Investigator

    • Principal Investigator
      NAKAUCHI Hiromitsu, 中村 幸夫
    • Project Period (FY)
      1992 – 1994
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      内科学一般
    • Research Institution
      University of Tsukuba
      The Institute of Physical and Chemical Research
  •  GENERATION OF NK CELLS FROM CD34+ HEMATOPOIETIC STEM CELLSPrincipal Investigator

    • Principal Investigator
      NAKAUCHI Hiromitsu, 渋谷 彰
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      THE INSTITUTE OF PFYSICAL AND CHEMICAL RESEARCH
      University of Tsukuba
  •  造血幹細胞に発現されている細胞表面機能分子の分子生物学的解析Principal Investigator

    • Principal Investigator
      中内 啓光
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The Institute of Physical and Chemical Research
  •  造血幹細胞に発現されている細胞表面機能分子の分子生物学的解析Principal Investigator

    • Principal Investigator
      中内 啓光
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The Institute of Physical and Chemical Research
  •  Production of chimeric protein to scavenge immune complexes

    • Principal Investigator
      FUJITA Teizo
    • Project Period (FY)
      1990 – 1992
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      Immunology
    • Research Institution
      Fukushima Medical College
  •  Development of the Methods for Regulated Expression of Transduced Gene in Transkaryotic Gene Therapy

    • Principal Investigator
      ITAKURA Mitsuo
    • Project Period (FY)
      1989 – 1991
    • Research Category
      Grant-in-Aid for Developmental Scientific Research
    • Research Field
      内分泌・代謝学
    • Research Institution
      The University of Tokushima
      University of Tsukuba
  •  Molecular Structure and Function of Lyt-2 and Lyt-3Principal Investigator

    • Principal Investigator
      HIRAMITSU Nakauchi
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Immunology
    • Research Institution
      Juntendo University
  •  マウス及びヒトT細胞白血病の転移におけるT細胞クロノタイプ及び分化抗原の転換

    • Principal Investigator
      OKUMURA Ko
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Juntendo University
  •  Immuno Molecular Analysis of Suppressor T cell receptor

    • Principal Investigator
      OKUMURA Ko
    • Project Period (FY)
      1986 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Immunology
    • Research Institution
      Juntendo University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 Other

All Journal Article Presentation Book Patent Other

  • [Book] 幹細胞研究と再生医療2013

    • Author(s)
      中内啓光(編集)
    • Total Pages
      238
    • Publisher
      南山堂
    • Data Source
      KAKENHI-PROJECT-24249056
  • [Book] 幹細胞研究と再生医療2013

    • Author(s)
      中内啓光(編集)
    • Total Pages
      238
    • Publisher
      南山堂
    • Data Source
      KAKENHI-PLANNED-23106004
  • [Book] 直伝!フローサイトメトリー2013

    • Author(s)
      中内啓光(監修)清田純(編集)
    • Total Pages
      278
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PLANNED-23106004
  • [Book] 直伝!フローサイトメトリー2013

    • Author(s)
      中内啓光(監修)清田純(編集)
    • Total Pages
      278
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PROJECT-24249056
  • [Book] 再生医療のしくみ2006

    • Author(s)
      八代嘉美, 中内啓光
    • Total Pages
      166
    • Publisher
      日本実業出版社
    • Data Source
      KAKENHI-PROJECT-14081202
  • [Book] 再生医療のしくみ2006

    • Author(s)
      八代嘉美, 中内啓光
    • Total Pages
      166
    • Publisher
      日本実業出版社
    • Data Source
      KAKENHI-PROJECT-17209036
  • [Book] 再生医療のしくみ2006

    • Author(s)
      八代嘉美, 中内啓光
    • Total Pages
      166
    • Publisher
      日本実業出版社
    • Data Source
      KAKENHI-PROJECT-14081101
  • [Journal Article] Physioxia improves the selectivity of hematopoietic stem cell expansion cultures2023

    • Author(s)
      Igarashi Kyomi J.、Kucinski Iwo、Chan Yan Yi、Tan Tze-Kai、Khoo Hwei Minn、Kealy David、Bhadury Joydeep、Hsu Ian、Ho Pui Yan、Niizuma Kouta、Hickey John W.、Nolan Garry P.、Bridge Katherine S.、Czechowicz Agnieszka、Gottgens Berthold、Nakauchi Hiromitsu、Wilkinson Adam C.
    • Journal Title

      Blood Advances

      Volume: 7 Issue: 14 Pages: 3366-3377

    • DOI

      10.1182/bloodadvances.2023009668

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H05695
  • [Journal Article] Chemically defined cytokine-free expansion of human haematopoietic stem cells2023

    • Author(s)
      Sakurai Masatoshi、Ishitsuka Kantaro、Ito Ryoji、Wilkinson Adam C.、Kimura Takaharu、Mizutani Eiji、Nishikii Hidekazu、Sudo Kazuhiro、Becker Hans Jiro、Takemoto Hiroshi、Sano Tsubasa、Kataoka Keisuke、Takahashi Satoshi、Nakamura Yukio、Kent David G et al.
    • Journal Title

      Nature

      Volume: 615 Issue: 7950 Pages: 127-133

    • DOI

      10.1038/s41586-023-05739-9

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03707, KAKENHI-PROJECT-21F21108, KAKENHI-PROJECT-20K06477, KAKENHI-PROJECT-23K21401, KAKENHI-PROJECT-20H05695
  • [Journal Article] Streamlined and quantitative detection of chimerism using digital PCR2022

    • Author(s)
      Suchy Fabian P.、Nishimura Toshiya、Seki Shinsuke、Wilkinson Adam C.、Higuchi Maimi、Hsu Ian、Zhang Jinyu、Bhadury Joydeep、Nakauchi Hiromitsu
    • Journal Title

      Scientific Reports

      Volume: 12 Issue: 1 Pages: 10233-10233

    • DOI

      10.1038/s41598-022-14467-5

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06023, KAKENHI-PROJECT-20H05695
  • [Journal Article] Identification and characterization of in vitro expanded hematopoietic stem cells2022

    • Author(s)
      Che James L C、Bode Daniel、Kucinski Iwo、Cull Alyssa H、Bain Fiona、Becker Hans J、Jassinskaja Maria、Barile Melania、Boyd Grace、Belmonte Miriam et al.
    • Journal Title

      EMBO reports

      Volume: 23 Issue: 10

    • DOI

      10.15252/embr.202255502

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03707, KAKENHI-PROJECT-21F21108, KAKENHI-PROJECT-23K21401, KAKENHI-PROJECT-20H05695
  • [Journal Article] Cas9-AAV6 gene correction of beta-globin in autologous HSCs improves sickle cell disease erythropoiesis in mice2021

    • Author(s)
      Wilkinson AC, Dever DP, Baik R, Camarena J, Hsu I, Charlesworth CT, Morita C, Nakauchi H, Porteus MH.
    • Journal Title

      Nat Commun

      Volume: 1 Issue: 1 Pages: 686-686

    • DOI

      10.1038/s41467-021-20909-x

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H05695
  • [Journal Article] Stabilizing hematopoietic stem cells in vitro.2020

    • Author(s)
      Wilkinson AC, Nakauchi H.
    • Journal Title

      Curr Opin Genet Dev.

      Volume: 64 Pages: 1-5

    • DOI

      10.1016/j.gde.2020.05.035

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H00538, KAKENHI-PROJECT-20H05695
  • [Journal Article] Haematopoietic stem cell self-renewal in vivo and ex vivo.2020

    • Author(s)
      Wilkinson AC, Igarashi KJ, Nakauchi H.
    • Journal Title

      Nat Rev Genet.

      Volume: 21 Issue: 9 Pages: 541-554

    • DOI

      10.1038/s41576-020-0241-0

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H00538, KAKENHI-PROJECT-20H05695
  • [Journal Article] In vivo and ex vivo haematopoietic stem cell expansion2020

    • Author(s)
      Yamamoto Ryo、Wilkinson Adam C.、Nakauchi Hiromitsu
    • Journal Title

      Current Opinion in Hematology

      Volume: 27 Issue: 4 Pages: 273-278

    • DOI

      10.1097/moh.0000000000000593

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H05695
  • [Journal Article] In vivo clonal analysis of aging hematopoietic stem cells.Mech Ageing Dev.2020

    • Author(s)
      Yamamoto R, Nakauchi H.
    • Journal Title

      Mech Ageing Dev.

      Volume: 192 Pages: 111378-111378

    • DOI

      10.1016/j.mad.2020.111378

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H00538
  • [Journal Article] Diamond Blackfan anemia is mediated by hyperactive Nemo-like kinase.2020

    • Author(s)
      Wilkes MC, Siva K, Chen J, Varetti G, Youn MY, Chae H, Ek F, Olsson R, Lundback T, Dever DP, Nishimura T, Narla A, Glader B, Nakauchi H,
    • Journal Title

      Nat Commun.

      Volume: 11 Issue: 1 Pages: 3344-3344

    • DOI

      10.1038/s41467-020-17100-z

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H00538
  • [Journal Article] In vivo and ex vivo haematopoietic stem cell expansion.2020

    • Author(s)
      Yamamoto R, Wilkinson AC, Nakauchi H.
    • Journal Title

      Curr Opin Hematol.

      Volume: 27 Pages: 273-278

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H00538
  • [Journal Article] Spred1 Safeguards Hematopoietic Homeostasis against Diet-Induced Systemic Stress2018

    • Author(s)
      Tadokoro Yuko、Hoshii Takayuki、Yamazaki Satoshi、Eto Koji、Ema Hideo、Kobayashi Masahiko、Ueno Masaya、Ohta Kumiko、Arai Yuriko、Hara Eiji、Harada Kenichi、Oshima Masanobu、Oshima Hiroko、Arai Fumio、Yoshimura Akihiko、Nakauchi Hiromitsu、Hirao Atsushi
    • Journal Title

      Cell Stem Cell

      Volume: 22 Issue: 5 Pages: 713-725

    • DOI

      10.1016/j.stem.2018.04.002

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09919, KAKENHI-PUBLICLY-17H05638, KAKENHI-PUBLICLY-18H05095, KAKENHI-ORGANIZER-26115001, KAKENHI-PROJECT-15H02361, KAKENHI-PROJECT-16H02661, KAKENHI-PROJECT-17H04208, KAKENHI-PROJECT-17H05086, KAKENHI-PROJECT-16K09824, KAKENHI-PROJECT-17K19585, KAKENHI-INTERNATIONAL-15K21751, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-18H04164
  • [Journal Article] Changing concepts in hematopoietic stem cells.2018

    • Author(s)
      Yamamoto R, Wilkinson AC, Nakauchi H.
    • Journal Title

      Science

      Volume: 362 Issue: 6417 Pages: 895-896

    • DOI

      10.1126/science.aat7873

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H02661
  • [Journal Article] Dissection of Signaling Events Downstream of the c-Mpl Receptor in Murine Hematopoietic Stem Cells Via Motif-Engineered Chimeric Receptors2018

    • Author(s)
      Saka Koichiro、Lai Chen-Yi、Nojima Masanori、Kawahara Masahiro、Otsu Makoto、Nakauchi Hiromitsu、Nagamune Teruyuki
    • Journal Title

      Stem Cell Rev. Rep.

      Volume: 14 Issue: 1 Pages: 101-109

    • DOI

      10.1007/s12015-017-9768-7

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19007, KAKENHI-PROJECT-15H02319, KAKENHI-PROJECT-16H02661
  • [Journal Article] Using patient-derived iPSCs to develop humanized mouse models for chronic myelomonocytic leukemia and therapeutic drug identification, including liposomal clodronate.2018

    • Author(s)
      1.Taoka K, Arai S, Kataoka K, Hosoi M, Miyauchi M, Yamazaki S, Honda A, Aixinjueluo W, Kobayashi T, Kumano K, Yoshimi A, Otsu M, Niwa A, Nakahata T, Nakauchi H, Kurokawa M.
    • Journal Title

      Scientific Reports

      Volume: 8 Issue: 1 Pages: 15855-15867

    • DOI

      10.1038/s41598-018-34193-1

    • NAID

      120006534582

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09631, KAKENHI-PROJECT-18K16111, KAKENHI-PROJECT-16H02661, KAKENHI-PROJECT-18H04052
  • [Journal Article] Generation of Vascular Endothelial Cells and Hematopoietic Cells by Blastocyst Complementation.2018

    • Author(s)
      Hamanaka S, Umino A, Sato H, Hayama T, Yanagida A, Mizuno N, Kobayashi T, Kasai M, Suchy FP, Yamazaki S, Masaki H, Yamaguchi T, Nakauchi H.
    • Journal Title

      Stem Cell Reports.

      Volume: 11(4) Issue: 4 Pages: 988-997

    • DOI

      10.1016/j.stemcr.2018.08.015

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08623, KAKENHI-PROJECT-17K10536, KAKENHI-PUBLICLY-18H05095, KAKENHI-PROJECT-16H02661, KAKENHI-PROJECT-17H05086, KAKENHI-PLANNED-18H05548
  • [Journal Article] Large-Scale Clonal Analysis Resolves Aging of the Mouse Hematopoietic Stem Cell Compartment.2018

    • Author(s)
      Yamamoto, R., Wilkinson, A.C., Ooehara, J., Lan, X., Lai, C.Y., Nakauchi, Y., Pritchard, J.K., and Nakauchi, H.
    • Journal Title

      Cell Stem Cell

      Volume: 22 Issue: 4 Pages: 600-607

    • DOI

      10.1016/j.stem.2018.03.013

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H02661
  • [Journal Article] Branched-chain amino acid depletion conditions bone marrow for hematopoietic stem cell transplantation avoiding amino acid imbalance-associated toxicity.2018

    • Author(s)
      Wilkinson AC, Morita M, Nakauchi H, Yamazaki S.
    • Journal Title

      Exp Hematol.

      Volume: 63 Pages: 12-16

    • DOI

      10.1016/j.exphem.2018.04.004

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-18H05095, KAKENHI-PROJECT-16H02661, KAKENHI-PROJECT-17H05086
  • [Journal Article] Integrated Stress Response Activity Marks Stem Cells in Normal Hematopoiesis and Leukemia.2018

    • Author(s)
      van Galen P, Mbong N, Kreso A, Schoof EM, Wagenblast E, Ng SWK, Krivdova G, Jin L, Nakauchi H, Dick JE.
    • Journal Title

      Cell Rep

      Volume: 25 Issue: 5 Pages: 1109-1117

    • DOI

      10.1016/j.celrep.2018.10.021

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H02661
  • [Journal Article] Designing Motif-Engineered Receptors To Elucidate Signaling Molecules Important for Proliferation of Hematopoietic Stem Cells.2018

    • Author(s)
      Ishizuka S, Lai CY, Otsu M, Nakauchi H, Nagamune T, Kawahara M.
    • Journal Title

      ACS Synth Biol.

      Volume: 7 Issue: 7 Pages: 1709-1714

    • DOI

      10.1021/acssynbio.8b00163

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H02661, KAKENHI-PROJECT-18H01792, KAKENHI-PROJECT-17K19007
  • [Journal Article] PhysiologicalSrsf2P95H expression causes impaired hematopoietic stem cell functions and aberrant RNA splicing in mice2017

    • Author(s)
      Kon Ayana、Yamazaki Satoshi、Nannya Yasuhito、Kataoka Keisuke、Ota Yasunori、Nakagawa Masahiro Marshall、Yoshida Kenichi、Shiozawa Yusuke、Morita Maiko、Yoshizato Tetsuichi、Sanada Masashi、Nakayama Manabu、Koseki Haruhiko、Nakauchi Hiromitsu、Ogawa Seishi
    • Journal Title

      Blood

      Volume: 131 Issue: 6 Pages: 621-635

    • DOI

      10.1182/blood-2017-01-762393

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26115009, KAKENHI-PROJECT-16H02661, KAKENHI-PROJECT-17H05086, KAKENHI-PROJECT-16K19574
  • [Journal Article] Novel TPO receptor agonist TA-316 contributes to platelet biogenesis from human iPS cells.2017

    • Author(s)
      Ayako Aihara, Tomo Koike, Natsuki Abe, Sou Nakamura, Akira Sawaguchi, Takanori Nakamura, Naoshi Sugimoto, Hiromitsu Nakauchi, Taito Nishino and Koji Eto
    • Journal Title

      Blood Advances

      Volume: 1 Issue: 7 Pages: 468-476

    • DOI

      10.1182/bloodadvances.2016000844

    • NAID

      120006488581

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H03005, KAKENHI-PROJECT-16H02661
  • [Journal Article] Pharmacological targeting of plasmin prevents lethality and tissue damage in a murine model of macrophage activation syndrome2017

    • Author(s)
      1.Shimazu H, Munakata S, Tashiro Y, Salama Y, Eiamboonser S, Ohta Y, Onoda H, Tsuda Y, Okada Y, Nakauchi H, Heissig B and Hattori K
    • Journal Title

      Blood

      Volume: 印刷中 Issue: 1 Pages: 59-72

    • DOI

      10.1182/blood-2016-09-738096

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461415, KAKENHI-PROJECT-16K09821, KAKENHI-PROJECT-16K19956, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-16K08333, KAKENHI-PROJECT-16K09866, KAKENHI-PROJECT-17K09941, KAKENHI-PROJECT-16H02661, KAKENHI-PROJECT-15K21373
  • [Journal Article] Continuous cell supply from Krt7-expressing hematopoietic stem cells during native hematopoiesis revealed by targeted in vivo gene transfer method.2017

    • Author(s)
      Tajima Y, Ito K, Umino A, Wilkinson AC, Nakauchi H, Yamazaki S
    • Journal Title

      Sci Rep

      Volume: 18 Issue: 1 Pages: 40684-40684

    • DOI

      10.1038/srep40684

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25713037, KAKENHI-PROJECT-16H02661, KAKENHI-PROJECT-16K15501
  • [Journal Article] Pre-Transplantation Blockade of TNF-α-Mediated Oxygen Species Accumulation Protects Hematopoietic Stem Cells.2017

    • Author(s)
      Ishida T, Suzuki S, Lai CY, Yamazaki S, Kakuta S, Iwakura Y, Nojima M, Takeuchi Y, Higashihara M, Nakauchi H, Otsu M.
    • Journal Title

      Stem Cells.

      Volume: 35 Issue: 4 Pages: 989-1002

    • DOI

      10.1002/stem.2524

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-16H02661, KAKENHI-PROJECT-25713037, KAKENHI-PROJECT-15K20949
  • [Journal Article] A Novel Mouse Model of iNKT Cell-deficiency Generated by CRISPR/Cas9 Reveals a Pathogenic Role of iNKT Cells in Metabolic Disease.2017

    • Author(s)
      Ren Y, Sekine-Kondo E, Shibata R, Kato-Itoh M, Umino A, Yanagida A, Satoh M, Inoue K, Yamaguchi T, Mochida K, Nakae S, Van Kaer L, Iwabuchi K, Nakauchi H, Watarai H.
    • Journal Title

      Sci Rep

      Volume: 7 Issue: 1 Pages: 12765-12765

    • DOI

      10.1038/s41598-017-12475-4

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K21347, KAKENHI-PROJECT-16H02661, KAKENHI-PROJECT-16K14591
  • [Journal Article] In?Vivo Generation of Engraftable Murine Hematopoietic Stem Cells by Gfi1b, c-Fos , and Gata2 Overexpression within Teratoma2017

    • Author(s)
      Tsukada Masao、Ota Yasunori、Wilkinson Adam C.、Becker Hans J.、Osato Motomi、Nakauchi Hiromitsu、Yamazaki Satoshi
    • Journal Title

      Stem Cell Reports

      Volume: 9 Issue: 4 Pages: 1024-1033

    • DOI

      10.1016/j.stemcr.2017.08.010

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H02661, KAKENHI-PROJECT-15H04312, KAKENHI-PROJECT-17H05086
  • [Journal Article] Mammalian Transcription Factor Networks: Recent Advances in Interrogating Biological Complexity2017

    • Author(s)
      Wilkinson Adam C.、Nakauchi Hiromitsu、G?ttgens Berthold
    • Journal Title

      Cell Syst

      Volume: 5 Issue: 4 Pages: 319-331

    • DOI

      10.1016/j.cels.2017.07.004

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H02661
  • [Journal Article] 1.An All-Recombinant Protein-Based Culture System Specifically Identifies Hematopoietic Stem Cell Maintenance Factors.2017

    • Author(s)
      Ieyasu A, Ishida R, Kimura T, Morita M, Wilkinson AC, Sudo K, Nishimura T, Ohehara J, Tajima Y, Lai CY, Otsu M, Nakamura Y, Ema H, Nakauchi H, Yamazaki S
    • Journal Title

      Stem Cell Reports

      Volume: 14 Issue: 3 Pages: 500-508

    • DOI

      10.1016/j.stemcr.2017.01.015

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25713037, KAKENHI-PROJECT-15K20949, KAKENHI-PROJECT-16K15501, KAKENHI-PROJECT-16H02661, KAKENHI-PROJECT-17H05086
  • [Journal Article] Setdb1 maintains hematopoietic stem and progenitor cells by restricting the ectopic activation of non-hematopoietic genes.2016

    • Author(s)
      Koide S, Oshima M, Takubo K, Yamazaki S, Nitta E, Saraya A, Aoyama K, Kato Y, Miyagi S, Nakajima-Takagi Y, Chiba T, Matsui H, Arai F, Suzuki Y, Kimura H, Nakauchi H, Suda T, Shinkai Y,Iwama A.
    • Journal Title

      Blood

      Volume: 128(5) Issue: 5 Pages: 638-649

    • DOI

      10.1182/blood-2016-01-694810

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-15H01513, KAKENHI-PLANNED-26115002, KAKENHI-PROJECT-26221309, KAKENHI-PROJECT-15H02544, KAKENHI-PROJECT-16H02661, KAKENHI-PROJECT-15J04258, KAKENHI-PROJECT-26293228, KAKENHI-PROJECT-15K09478, KAKENHI-PROJECT-16K09340, KAKENHI-PROJECT-16K09840, KAKENHI-PROJECT-16K19565, KAKENHI-PROJECT-16K20959
  • [Journal Article] Depleting dietary valine permits nonmyeloablative mouse hematopoietic stem cell transplantation2016

    • Author(s)
      Taya, Y., Ota, Y., Wilkinson, A. C., Kanazawa, A., Watarai, H., Kasai, M., Nakauchi, H. and Yamazaki, S
    • Journal Title

      Science

      Volume: 354 Issue: 6316 Pages: 1152-1155

    • DOI

      10.1126/science.aag3145

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H02661, KAKENHI-PROJECT-25713037, KAKENHI-PROJECT-16K15501
  • [Journal Article] Spatiotemporal Reconstruction of the Human Blastocyst by Single-Cell Gene-Expression Analysis Informs Induction of Naive Pluripotency2016

    • Author(s)
      Durruthy-Durruthy, J., Wossidlo, M., Pai, S., Takahashi, Y., Kang, G., Omberg, L., Chen, B., Nakauchi, H., Reijo Pera, R. and Sebastiano, V
    • Journal Title

      Dev Cell

      Volume: 38 Issue: 1 Pages: 100-15

    • DOI

      10.1016/j.devcel.2016.06.014

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H02661
  • [Journal Article] Fetal Hematopoietic Stem Cell Transplantation Fails to Fully Regenerate the B-Lymphocyte Compartment.2016

    • Author(s)
      Ghosn EE, Waters J, Phillips M, Yamamoto R, Long BR, Yang Y, Gerstein R, Stoddart CA, Nakauchi H, Herzenberg LA
    • Journal Title

      Stem Cell Reports

      Volume: 6(1) Issue: 1 Pages: 137-49

    • DOI

      10.1016/j.stemcr.2015.11.011

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-23106004
  • [Journal Article] Non-myeloablative preconditioning with ACK2 (anti-c-kit antibody) is efficient in bone marrow transplantation for murine models of mucopolysaccharidosis type II2016

    • Author(s)
      Yokoi, T., Yokoi, K., Akiyama, K., Higuchi, T., Shimada, Y., Kobayashi, H., Sato, T., Ohteki, T., Otsu, M., Nakauchi, H., Ida, H. and Ohashi, T
    • Journal Title

      Mol Genet Meta

      Volume: 119 Issue: 3 Pages: 232-238

    • DOI

      10.1016/j.ymgme.2016.08.003

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H02661, KAKENHI-PROJECT-26253029, KAKENHI-PROJECT-15K15150
  • [Journal Article] Hoxb5 marks long-term haematopoietic stem cells and reveals a homogenous perivascular niche2016

    • Author(s)
      Chen JY, Miyanishi M, Wang SK, Yamazaki S, Sinha R, Kao KS, Seita J, Sahoo D, Nakauchi H, Weissman IL
    • Journal Title

      Nature

      Volume: 530(7589) Issue: 7589 Pages: 223-7

    • DOI

      10.1038/nature16943

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-23106004, KAKENHI-PROJECT-25640044, KAKENHI-PROJECT-16H02661
  • [Journal Article] Multiple allogeneic progenitors in combination function as a unit to support early transient hematopoiesis in transplantation2016

    • Author(s)
      Ishida, T., Takahashi, S., Lai, C. Y., Nojima, M., Yamamoto, R., Takeuchi, E., Takeuchi, Y., Higashihara, M., Nakauchi, H. and Otsu, M
    • Journal Title

      J Exp Med

      Volume: 213 Pages: 1865-80

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H02661
  • [Journal Article] Quantification of adult T-cell leukemia/lymphoma cells using simple four-color flow cytometry2015

    • Author(s)
      Ishigaki T, Zaike Y, Nojima M, Kobayashi S, Ohno N, Uchimaru K, Tojo A, Nakauchi H, Watanabe N
    • Journal Title

      Clinical Chemistry and Laboratory Medicine

      Volume: 53(1) Issue: 1 Pages: 85-93

    • DOI

      10.1515/cclm-2014-0183

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-14J07244, KAKENHI-PROJECT-24249056, KAKENHI-PROJECT-24591383, KAKENHI-PLANNED-23106004
  • [Journal Article] T-cell-restricted T-bet overexpression induces aberrant hematopoiesis of myeloid cells and impairs function of macrophages in the lung2015

    • Author(s)
      Iriguchi S, Kikuchi N, Kaneko S, Noguchi E, Morishima Y, Matsuyama M, Yoh K, Takahashi S, Nakauchi H, Ishii Y
    • Journal Title

      Blood

      Volume: 125 Issue: 2 Pages: 370-82

    • DOI

      10.1182/blood-2014-05-575225

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-23106004, KAKENHI-PROJECT-24249056, KAKENHI-PROJECT-24390251, KAKENHI-PROJECT-24591152, KAKENHI-PUBLICLY-25114707, KAKENHI-PROJECT-26670578, KAKENHI-PROJECT-26461178
  • [Journal Article] Effective treatment against severe graft-versus-host disease with allele-specific anti-HLA monoclonal antibody in a humanized mouse mode2015

    • Author(s)
      Nakauchi Y, Yamazaki S, Napier SC, Usui J, Ota Y, Takahashi S, Watanabe N, Nakauchi H
    • Journal Title

      Experimental hematology

      Volume: 43 Issue: 2 Pages: 79-88

    • DOI

      10.1016/j.exphem.2014.10.008

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24249056, KAKENHI-PROJECT-25461206, KAKENHI-PROJECT-25713037
  • [Journal Article] Inhibition of plasmin attenuates murine acute graft-versus-host disease mortality by suppressing the matrix metalloproteinase-9-dependent inflammatory cytokine storm and effector cell trafficking.2015

    • Author(s)
      A Sato, C Nishida, K Sato-Kusubata, M Ishihara, Y Tashiro, I Gritli, H Shimazu, S Munakata, H Yagita, K Okumura, Y Tsuda, Y Okada, A Tojo, H Nakauchi, S Takahashi, B Heissig and K Hattori
    • Journal Title

      Leukemia

      Volume: 29 Issue: 1 Pages: 145-56

    • DOI

      10.1038/leu.2014.151

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-22112007, KAKENHI-PROJECT-24249056, KAKENHI-PROJECT-24591382, KAKENHI-PROJECT-25460164, KAKENHI-PROJECT-25861215
  • [Journal Article] 腎臓由来ヒトiPS細胞を応用した新規CKD治療法の開発2015

    • Author(s)
      高瀬 敦、菱川 慶一、中内 啓光
    • Journal Title

      大和証券ヘルス財団研究業績集

      Volume: 38 Pages: 51-56

    • Open Access
    • Data Source
      KAKENHI-PROJECT-25461208
  • [Journal Article] Vascularized and Complex Organ Buds from Diverse Tissues via Mesenchymal Cell-Driven Condensation2015

    • Author(s)
      T. Takebe, M. Eomura, E. Yoshizawa, M. Kimura, H. Koike, Y. Ueno, T. Matsuzaki, T. Yamazaki, T. Toyohara, K. Osafune, H. Nakauchi, H. Y. Yoshikawa, H. Taniguchi
    • Journal Title

      Cell Stem Cell

      Volume: 16 Issue: 5 Pages: 556-565

    • DOI

      10.1016/j.stem.2015.03.004

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-13J08820, KAKENHI-PROJECT-24680050, KAKENHI-PLANNED-23106004, KAKENHI-PUBLICLY-26106721, KAKENHI-PROJECT-25253079, KAKENHI-PROJECT-15H05677, KAKENHI-PROJECT-25461956
  • [Journal Article] Circulating cells contribute to cardiomyocyte regeneration after injury2015

    • Author(s)
      Wu JM, Hsueh YC, Ch'ang HJ, Luo CY, Wu LW, Nakauchi H, Hsieh PC
    • Journal Title

      Circulation research

      Volume: 116 Issue: 4 Pages: 633-41

    • DOI

      10.1161/circresaha.116.304564

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24249056, KAKENHI-PLANNED-23106004
  • [Journal Article] Targeted organ generation using Mixl1-inducible mouse pluripotent stem cells in blastocyst complementation2015

    • Author(s)
      Kobayashi T, Kato-Itoh M, Nakauchi H
    • Journal Title

      Stem Cells Dev

      Volume: 24(2) Issue: 2 Pages: 182-9

    • DOI

      10.1089/scd.2014.0270

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23106004
  • [Journal Article] Screening of Drugs to Treat 8p11 Myeloproliferative Syndrome Using Patient-Derived Induced Pluripotent Stem Cells with Fusion Gene CEP110-FGFR12015

    • Author(s)
      Yamamoto S, Otsu M, Matsuzaka E, Konishi C, Takagi H, Hanada S, Mochizuki S, Nakauchi H, Imai K, Tsuji K, Ebihara Y
    • Journal Title

      PloS one

      Volume: 10 Issue: 3 Pages: e0120841-e0120841

    • DOI

      10.1371/journal.pone.0120841

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24249056, KAKENHI-PROJECT-24390272
  • [Journal Article] Effect of donor chimerism to reduce the level of glycosaminoglycans following bone marrow transplantation in a murine model of mucopolysaccharidosis type II2015

    • Author(s)
      Yokoi K, Akiyama K, Kaneshiro E, Higuchi T, Shimada Y, Kobayashi H, Akiyama M, Otsu M, Nakauchi H, Ohashi T, Ida H
    • Journal Title

      Journal of inherited metabolic disease

      Volume: 38 Issue: 2 Pages: 333-40

    • DOI

      10.1007/s10545-014-9800-x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249056, KAKENHI-PROJECT-25860884
  • [Journal Article] Cell Adhesion Minimization by a Novel Mesh Culture Method Mechanically Directs Trophoblast Differentiation and Self-Assembly Organization of Human Pluripotent Stem Cells2015

    • Author(s)
      Okeyo O. Kennedy, Osamu Kurosawa, Satoshi Yamazaki, Hidehiro Oana, Hidetoshi Kotera, Hiromitsu Nakauchi, Masao Washizu
    • Journal Title

      Tissue Engineering Part C

      Volume: なし Issue: 10 Pages: 1105-15

    • DOI

      10.1089/ten.tec.2015.0038

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25790034, KAKENHI-PLANNED-23106004, KAKENHI-PROJECT-23246045, KAKENHI-PROJECT-25713037, KAKENHI-PUBLICLY-26106710, KAKENHI-PROJECT-15H02009
  • [Journal Article] Novel strategies for liver therapy using stem cells2015

    • Author(s)
      Rashid T, Takebe T, Nakauchi H
    • Journal Title

      Gut

      Volume: 64(1) Issue: 1 Pages: 1-4

    • DOI

      10.1136/gutjnl-2014-307480

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-23106004
  • [Journal Article] Successful reprogramming of epiblast stem cells by blocking nuclear localization of beta-catenin2015

    • Author(s)
      Murayama H, Masaki H, Sato H, Hayama T, Yamaguchi T, Nakauchi H
    • Journal Title

      Stem cell reports

      Volume: 4 Issue: 1 Pages: 103-13

    • DOI

      10.1016/j.stemcr.2014.12.003

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-23106004, KAKENHI-PROJECT-26460358
  • [Journal Article] Enzyme augmentation therapy enhances the therapeutic efficacy of bone marrow transplantation in mucopolysaccharidosis type II mice.2014

    • Author(s)
      Akiyama K, Shimada Y, Higuchi T, Ohtsu M, Nakauchi H, Kobayashi H, Fukuda T, Ida H, Eto Y, Crawford BE, Brown JR, Ohashi T
    • Journal Title

      Mol Genet Metab.

      Volume: 111 Issue: 2 Pages: 139-46

    • DOI

      10.1016/j.ymgme.2013.09.013

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23106004, KAKENHI-PROJECT-24249056
  • [Journal Article] Five-lineage clonal analysis of hematopoietic stem/progenitor cells2014

    • Author(s)
      Yamamoto R, Morita Y, Nakauchi H
    • Journal Title

      Methods in molecular biology

      Volume: 1185 Pages: 237-45

    • DOI

      10.1007/978-1-4939-1133-2_16

    • ISBN
      9781493911325, 9781493911332
    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23106004, KAKENHI-PROJECT-24249056
  • [Journal Article] Nov/ccn3 regulates long-term repopulating activity of murine hematopoietic stem cells via integrin αvβ32014

    • Author(s)
      J. Ishihara, et al
    • Journal Title

      International Journal of Hematology

      Volume: (印刷中) Issue: 4 Pages: 393-406

    • DOI

      10.1007/s12185-014-1534-x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-13J00246, KAKENHI-ORGANIZER-22118001, KAKENHI-PLANNED-22118002, KAKENHI-PLANNED-23106004, KAKENHI-PROJECT-23249051, KAKENHI-PROJECT-24249056, KAKENHI-PROJECT-24300160, KAKENHI-PROJECT-25293097
  • [Journal Article] Developmental epigenetic modification regulates stochastic expression of clustered protocadherin genes, generating single neuron diversity.2014

    • Author(s)
      Toyoda S, Kawaguchi M, Kobayashi T, Tarusawa E, Toyama T, Okano M, Oda M, Nakauchi H, Yoshimura Y, Sanbo M, Hirabayashi M, Hirayama T, Hirabayashi T, Yagi T.
    • Journal Title

      Neuron

      Volume: 82 Issue: 1 Pages: 94-108

    • DOI

      10.1016/j.neuron.2014.02.005

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-221S0003, KAKENHI-PLANNED-23106004, KAKENHI-PROJECT-23500447, KAKENHI-PROJECT-23657149, KAKENHI-PROJECT-24700410, KAKENHI-PUBLICLY-25115720, KAKENHI-PUBLICLY-25123711, KAKENHI-PUBLICLY-26115516, KAKENHI-PROJECT-26350980, KAKENHI-PROJECT-26640012
  • [Journal Article] Acid sphingomyelinase modulates the autophagic process by controlling lysosomal biogenesis in Alzheimer's disease2014

    • Author(s)
      Lee JK, Jin HK, Park MH, Kim BR, Lee PH, Nakauchi H, Carter JE, He X, Schuchman EH, Bae JS
    • Journal Title

      The Journal of experimental medicine

      Volume: 211 Issue: 8 Pages: 1551-70

    • DOI

      10.1084/jem.20132451

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-23106004
  • [Journal Article] Expandable Megakaryocyte Cell Lines Enable Clinically Applicable Generation of Platelets from Human Induced Pluripotent Stem Cells.2014

    • Author(s)
      Nakamura S, Takayama N, Hirata S, Seo H, Endo H, Ochi K, Fujita KI, Koike T, Harimoto KI, Dohda T, Watanabe A, Okita K, Takahashi N, Sawaguchi A, Yamanaka S, Nakauchi H, Nishimura S, Eto K.
    • Journal Title

      Cell Stem Cell.

      Volume: 14 Issue: 4 Pages: 535-48

    • DOI

      10.1016/j.stem.2014.01.011

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-23106004, KAKENHI-PROJECT-24249056, KAKENHI-PROJECT-24300160, KAKENHI-PROJECT-25860236
  • [Journal Article] Down syndrome-associated haematopoiesis abnormalities created by chromosome transfer and genome editing technologies2014

    • Author(s)
      Kazuki Y, Yakura Y, Abe S, Osaki M, Kajitani N, Kazuki K, Takehara S, Honma K, Suemori H, Yamazaki S, Sakuma T, Toki T, Shimizu R, Nakauchi H, Yamamoto T, Oshimura M
    • Journal Title

      Scientific reports

      Volume: 4 Issue: 1 Pages: 6136-6136

    • DOI

      10.1038/srep06136

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-23106004, KAKENHI-PROJECT-24249056, KAKENHI-PROJECT-25221308, KAKENHI-PROJECT-25640044, KAKENHI-PROJECT-25713037, KAKENHI-PROJECT-25890014
  • [Journal Article] Gene Targeting Study Reveals Unexpected Expression of Brain expressed X-linked 2 in Endocrine and Tissue Stem/progenitor Cells in Mice2014

    • Author(s)
      Keiichi Ito, Satoshi Yamazaki, Ryo Yamamoto, Yoko Tajima, Ayaka Yanagida, Toshihiro Kobayashi, Megumi Kato-Itoh, Shigeru Kakuta, Yoichiro Iwakura, Hiromitsu Nakauchi, Akihide Kamiya,
    • Journal Title

      J Biol Chem

      Volume: 289(43) Issue: 43 Pages: 29892-911

    • DOI

      10.1074/jbc.m114.580084

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-13J05787, KAKENHI-PLANNED-23106004, KAKENHI-PROJECT-24249056, KAKENHI-PROJECT-24500488, KAKENHI-PROJECT-25640044, KAKENHI-PROJECT-25713037
  • [Journal Article] Bone marrow Schwann cells induce hematopoietic stem cell hibernation2014

    • Author(s)
      Yamazaki S, Nakauchi H
    • Journal Title

      International journal of hematology

      Volume: 99 Issue: 6 Pages: 695-8

    • DOI

      10.1007/s12185-014-1588-9

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-23106004, KAKENHI-PROJECT-24249056, KAKENHI-PROJECT-25713037
  • [Journal Article] Revisiting the flight of Icarus: making human organs from PSCs with large animal chimeras2014

    • Author(s)
      Rashid T, Kobayashi T, Nakauchi H
    • Journal Title

      Cell stem cell

      Volume: 15 Issue: 4 Pages: 406-9

    • DOI

      10.1016/j.stem.2014.09.013

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-23106004
  • [Journal Article] The generation of induced pluripotent stem cells (iPSCs) from patients with infantile and late-onset types of Pompe disease and the effects of treatment with acid-alpha-glucosidase in Pompe's iPSCs2014

    • Author(s)
      Higuchi T, Kawagoe S, Otsu M, Shimada Y, Kobayashi H, Hirayama R, Eto K, Ida H, Ohashi T, Nakauchi H, Eto Y
    • Journal Title

      Molecular genetics and metabolism

      Volume: 112 Issue: 1 Pages: 44-8

    • DOI

      10.1016/j.ymgme.2014.02.012

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249056, KAKENHI-PROJECT-24300160
  • [Journal Article] The TIF1β-HP1 System Maintains Transcriptional Integrity of Hematopoietic Stem Cells.2014

    • Author(s)
      Miyagi S, Koide S, Saraya A, Wendt GR, Oshima M, Konuma T, Yamazaki S, Mochizuki-Kashio M, Nakajima-Takagi Y, Wang C, Chiba T, Kitabayashi I, Nakauchi H, Iwama A.
    • Journal Title

      Stem Cell Reports.

      Volume: 2 Issue: 2 Pages: 145-52

    • DOI

      10.1016/j.stemcr.2013.12.008

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-23106004, KAKENHI-PROJECT-23689039, KAKENHI-PROJECT-24249054, KAKENHI-PROJECT-24249056, KAKENHI-PROJECT-25893049, KAKENHI-PROJECT-221S0002
  • [Journal Article] Derivation of embryonic stem cell lines from parthenogenetically developing rat blastocysts.2014

    • Author(s)
      Hirabayashi M, Goto T, Tamura C, Sanbo M, Hara H, Kato-Itoh M, Sato H, Kobayashi T, Nakaushi H, Hochi S.
    • Journal Title

      Stem Cells and Development

      Volume: VOL.23 Issue: 2 Pages: 107-114

    • DOI

      10.1089/scd.2013.0200

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-13J10439, KAKENHI-PLANNED-23106004, KAKENHI-PROJECT-24249056, KAKENHI-PROJECT-25290037
  • [Journal Article] Impaired hematopoietic differentiation of RUNX1-mutated induced pluripotent stem cells derived from FPD/AML patients2014

    • Author(s)
      Sakurai M, Kunimoto H, Watanabe N, Fukuchi Y, Yuasa S, Yamazaki S, Nishimura T, Sadahira K, Fukuda K, Okano H, Nakauchi H, Morita Y, Matsumura I, Kudo K, Ito E, Ebihara Y, Tsuji K, Harada Y, Harada H, Okamoto S, Nakajima H
    • Journal Title

      Leukemia

      Volume: 28 Issue: 12 Pages: 2344-54

    • DOI

      10.1038/leu.2014.136

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24249039, KAKENHI-PROJECT-24249056, KAKENHI-PROJECT-24390272, KAKENHI-PROJECT-24591398, KAKENHI-PROJECT-24659467, KAKENHI-PUBLICLY-25118716, KAKENHI-PUBLICLY-25130712, KAKENHI-PROJECT-25461422, KAKENHI-PROJECT-25461439, KAKENHI-PROJECT-25713037, KAKENHI-PROJECT-26257501, KAKENHI-PROJECT-26293243, KAKENHI-PROJECT-26670511
  • [Journal Article] Histone demethylase Jmjd3 is required for the development of subsets of retinal bipolar cells.2014

    • Author(s)
      Iida A, Iwagawa T, Kuribayashi H, Satoh S, Mochizuki Y, Baba Y, Nakauchi H, Furukawa T, Koseki H, Murakami A, Watanabe S.
    • Journal Title

      Proc Natl Acad Sci U S A.

      Volume: 111 Issue: 10 Pages: 3751-6

    • DOI

      10.1073/pnas.1311480111

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-23106004, KAKENHI-PROJECT-23390074, KAKENHI-PUBLICLY-25118708
  • [Journal Article] Clock gene Bmal1 is dispensable for intrinsic properties of murine hematopoietic stem cells.2014

    • Author(s)
      Ieyasu A, Tajima Y, Shimba S, Nakauchi H, Yamazaki S
    • Journal Title

      J Negat Results Biomed

      Volume: 13 Issue: 1 Pages: 4-4

    • DOI

      10.1186/1477-5751-13-4

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23590091, KAKENHI-PROJECT-24249056
  • [Journal Article] Generation of induced pluripotent stem cells derived from primary and secondary myelofibrosis patient samples2014

    • Author(s)
      Hosoi M, Kumano K, Taoka K, Arai S, Kataoka K, Ueda K, Kamikubo Y, Takayama N, Otsu M, Eto K, Nakauchi H, Kurokawa M
    • Journal Title

      Exp Hematol

      Volume: (in press) Issue: 9 Pages: 816-25

    • DOI

      10.1016/j.exphem.2014.03.010

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23591369, KAKENHI-PROJECT-24249056, KAKENHI-PROJECT-24300160, KAKENHI-PROJECT-25461420, KAKENHI-PROJECT-26461170
  • [Journal Article] Generation of Functional Oocytes by Xeno-Ectopic Transplantation of Primordial Germ Cells2014

    • Author(s)
      Hayama T, Yamaguchi T, Kato-Itoh M, Hamanaka S, Kawarai M, Sanbo M, Tamura C, Lee YS, Yanagida A, Murayama H, Mizuno N, Umino A, Sato H, Yamazaki S, Masaki H, Kobayashi T, Hirabayashi M, Nakauchi H
    • Journal Title

      Biol Reprod

      Volume: 91(4) 89 Issue: 4 Pages: 1-9

    • DOI

      10.1095/biolreprod.114.121640

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-13J05787, KAKENHI-PLANNED-23106004, KAKENHI-PROJECT-25290037, KAKENHI-PROJECT-25713037, KAKENHI-PROJECT-26460358
  • [Journal Article] Haploinsufficiency of Sf3b1 leads to compromised stem cell function but not to myelodysplasia.2014

    • Author(s)
      Matsunawa M, Yoshida K
    • Journal Title

      Leukemia

      Volume: (Epub ahead of print) Issue: 9 Pages: 1-7

    • DOI

      10.1038/leu.2014.73

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-12J04216, KAKENHI-PLANNED-22134006, KAKENHI-PLANNED-23106004, KAKENHI-PROJECT-23249052, KAKENHI-PROJECT-24249056, KAKENHI-PROJECT-24390242, KAKENHI-PROJECT-24659458, KAKENHI-PROJECT-25670152, KAKENHI-PROJECT-25670446, KAKENHI-PLANNED-26115009, KAKENHI-PROJECT-26221308, KAKENHI-PROJECT-26640075, KAKENHI-PROJECT-26890016
  • [Journal Article] Stage-specific roles for Cxcr4 signaling in murine hematopoietic stem/progenitor cells in the process of bone marrow repopulation.2014

    • Author(s)
      Lai CY, Yamazaki S, Okabe M, Suzuki S, Maeyama Y, Iimura Y, Onodera M, Kakuta S, Iwakura Y, Nojima M, Otsu M, Nakauchi H.
    • Journal Title

      Stem Cells.

      Volume: - Issue: 7 Pages: 1929-42

    • DOI

      10.1002/stem.1670

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23106004, KAKENHI-PROJECT-24249056, KAKENHI-PROJECT-24500488, KAKENHI-PROJECT-24659127
  • [Journal Article] Multicolor staining of globin subtypes reveals impaired globin switching during erythropoiesis in human pluripotent stem cells2014

    • Author(s)
      Ochi K, Takayama N, Hirose S, Nakahata T, Nakauchi H, Eto K
    • Journal Title

      Stem cells translational medicine

      Volume: 3 Issue: 7 Pages: 792-800

    • DOI

      10.5966/sctm.2013-0216

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249056, KAKENHI-PROJECT-24300160, KAKENHI-PROJECT-26670498
  • [Journal Article] Use of cell type-specific transcriptome to identify genes specifically involved in Müller glia differentiation during retinal development.2014

    • Author(s)
      Mochizuki Y, Iida A, Lyons E, Kageyama R, Nakauchi H, Murakami A, Watanabe S.
    • Journal Title

      Dev Neurobiol.

      Volume: 74 Issue: 4 Pages: 426-37

    • DOI

      10.1002/dneu.22131

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23106004, KAKENHI-PUBLICLY-25118708, KAKENHI-PROJECT-25670726
  • [Journal Article] A chemical probe that labels human pluripotent stem cells2014

    • Author(s)
      Hirata N, Nakagawa M, Fujibayashi Y, Yamauchi K, Murata A, Minami I, Tomioka M, Kondo T, Kuo TF, Endo H, Inoue H, Sato S, Ando S, Kawazoe Y, Aiba K, Nagata K, Kawase E, Chang YT, Suemori H, Eto K, Nakauchi H, Yamanaka S, Nakatsuji N, Ueda K, Uesugi M
    • Journal Title

      Cell reports

      Volume: 6 Issue: 6 Pages: 1165-74

    • DOI

      10.1016/j.celrep.2014.02.006

    • NAID

      120005466668

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-23106004, KAKENHI-PROJECT-23500446, KAKENHI-PROJECT-23510277, KAKENHI-PROJECT-24249056, KAKENHI-PROJECT-24510316, KAKENHI-PROJECT-24590353, KAKENHI-PROJECT-24615003, KAKENHI-PROJECT-25221203, KAKENHI-PROJECT-25560195, KAKENHI-PUBLICLY-26102728, KAKENHI-PROJECT-26220206, KAKENHI-PROJECT-26560445
  • [Journal Article] Mesenchymal progenitor cells in mouse fetal liver regulate differentiation and proliferation of hepatoblasts2014

    • Author(s)
      Ito Keiichi, Yanagida Ayaka, Okada Ken, Yamazaki Yuji, Nakauchi Hiromitsu, Kamiya Akihide
    • Journal Title

      Liver international

      Volume: (印刷中) Issue: 9 Pages: 1378-1390

    • DOI

      10.1111/liv.12387

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-13J05787, KAKENHI-PLANNED-23106004, KAKENHI-PROJECT-23689040, KAKENHI-PUBLICLY-24112505, KAKENHI-PROJECT-25670373
  • [Journal Article] Homeodomain transcription factor meis1 is a critical regulator of adult bone marrow hematopoiesis.2014

    • Author(s)
      Ariki R, Morikawa S, Mabuchi Y, Suzuki S, Nakatake M, Yoshioka K, Hidano S, Nakauchi H, Matsuzaki Y, Nakamura T, Goitsuka R.
    • Journal Title

      PLoS One.

      Volume: 9 Issue: 2 Pages: 87646-87646

    • DOI

      10.1371/journal.pone.0087646

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-23106004, KAKENHI-PROJECT-23240125, KAKENHI-ORGANIZER-24111001, KAKENHI-PROJECT-24249056, KAKENHI-PROJECT-24592965, KAKENHI-PROJECT-24659789, KAKENHI-PUBLICLY-25111513, KAKENHI-PROJECT-25292194, KAKENHI-PROJECT-25463226
  • [Journal Article] Generation of rejuvenated antigen-specific T cells by reprogramming to pluripotency and redifferentiation.2013

    • Author(s)
      Nishimura T, Koseki H, Nakauchi H. 他
    • Journal Title

      Cell Stem Cell.

      Volume: 12 Issue: 1 Pages: 114-26

    • DOI

      10.1016/j.stem.2012.11.002

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23249015, KAKENHI-PROJECT-23591413, KAKENHI-PROJECT-23592022, KAKENHI-PROJECT-23650622, KAKENHI-PROJECT-23791154, KAKENHI-PROJECT-24249056, KAKENHI-PROJECT-24300160, KAKENHI-PROJECT-24390257, KAKENHI-PLANNED-23106004
  • [Journal Article] Generation of engraftable hematopoietic stem cells from induced pluripotent stem cells by way of teratoma formation.2013

    • Author(s)
      Suzuki N, Yamazaki S, Yamaguchi T, Okabe M, Masaki H, Takaki S, Otsu M, Nakauchi H.
    • Journal Title

      Mol Ther.

      Volume: 21 Issue: 7 Pages: 1424-31

    • DOI

      10.1038/mt.2013.71

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23106004, KAKENHI-PROJECT-24249056, KAKENHI-PROJECT-24659127, KAKENHI-PROJECT-25293097, KAKENHI-PROJECT-25670471, KAKENHI-PROJECT-25670489
  • [Journal Article] Profiling of MicroRNA in Human and Mouse ES and iPS Cells Reveals Overlapping but Distinct MicroRNA Expression Patterns.2013

    • Author(s)
      Razak SR, Ueno K, Takayama N, Nariai N, Nagasaki M, Saito R, Koso H, Lai CY, Murakami M, Tsuji K, Michiue T, Nakauchi H, Otsu M, Watanabe S.
    • Journal Title

      PLoS One.

      Volume: 8 Issue: 9 Pages: e73532-e73532

    • DOI

      10.1371/journal.pone.0073532

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-23106004, KAKENHI-PROJECT-24249056, KAKENHI-PROJECT-24791840, KAKENHI-PUBLICLY-25118708, KAKENHI-PROJECT-25670471, KAKENHI-PROJECT-25670489
  • [Journal Article] Do pluripotent stem cells exist in adult mice as very small embryonic stem cells?2013

    • Author(s)
      Miyanishi M, Mori Y, Seita J, Chen JY, Karten S, Chan CK, Nakauchi H, Weissman IL.
    • Journal Title

      Stem Cell Reports.

      Volume: 1 Issue: 2 Pages: 198-208

    • DOI

      10.1016/j.stemcr.2013.07.001

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23106004, KAKENHI-PROJECT-24249056
  • [Journal Article] An in vitro expansion system for generation of human iPS cell-derived hepatic progenitor-like cells exhibiting a bipotent differentiation potential.2013

    • Author(s)
      Yanagida A, Ito K, Chikada H, Nakauchi H, Kamiya A.
    • Journal Title

      PLoS One.

      Volume: 8 Issue: 7 Pages: e67541-e67541

    • DOI

      10.1371/journal.pone.0067541

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23106004, KAKENHI-PROJECT-23689040, KAKENHI-PUBLICLY-24112505, KAKENHI-PROJECT-24249056, KAKENHI-PROJECT-25670373
  • [Journal Article] A retrospective analysis of germline competence in rat embryonic stem cell Lines2013

    • Author(s)
      Hirabayashi M
    • Journal Title

      Transgenic Res.

      Volume: 22 Issue: 2 Pages: 411-416

    • DOI

      10.1007/s11248-012-9638-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22300147, KAKENHI-PROJECT-25290037, KAKENHI-PLANNED-23106004
  • [Journal Article] Clonal analysis unveils self-renewing lineage-restricted progenitors generated directly from hematopoietic stem cells.2013

    • Author(s)
      Yamamoto R, Morita Y, Ooehara J, Hamanaka S, Onodera M, Rudolph KL, Ema H, Nakauchi H.
    • Journal Title

      Cell.

      Volume: 154 Issue: 5 Pages: 1112-26

    • DOI

      10.1016/j.cell.2013.08.007

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23106004, KAKENHI-PROJECT-23500490, KAKENHI-PROJECT-24249056, KAKENHI-PROJECT-25860784
  • [Journal Article] Generation of transgenic mouse line expressing Kusabira Orange throughout body, including erythrocytes, by random segregation of provirus method2013

    • Author(s)
      Hamanaka S, Ooehara J, Morita Y, Ema H, Takahashi S, Miyawaki A, Otsu M, Yamaguchi T, Onodera M, Nakauchi H
    • Journal Title

      Biochem Biophys Res Commun

      Volume: i435(4) Issue: 4 Pages: 586-91

    • DOI

      10.1016/j.bbrc.2013.05.017

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21220009, KAKENHI-PLANNED-23106004, KAKENHI-PROJECT-23500490, KAKENHI-PROJECT-24249056, KAKENHI-PROJECT-25670471, KAKENHI-PROJECT-25670489
  • [Journal Article] Immortalization of Erythroblasts by c-MYC and BCL-XL Enables Large-Scale Erythrocyte Production from Human Pluripotent Stem Cells.2013

    • Author(s)
      Hirose, S., N. Takayama, S. Nakamura, K. Nagasawa, K. Ochi, S. Hirata, S. Yamazaki, T. Yamaguchi, M. Otsu, S. Sano, N. Takahashi, A. Sawaguchi, M. Ito, T. Kato, H. Nakauchi, and K. Eto.
    • Journal Title

      Stem Cell Reports

      Volume: 1 Issue: 6 Pages: 499-508

    • DOI

      10.1016/j.stemcr.2013.10.010

    • NAID

      120005350227

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22220007, KAKENHI-PLANNED-23106004, KAKENHI-PROJECT-24249056, KAKENHI-PROJECT-24300160, KAKENHI-PROJECT-25670471, KAKENHI-PROJECT-25670489
  • [Journal Article] Wnt3a stimulates maturation of impaired neutrophils developed from severe congenital neutropenia-derived pluipotent stem cells with heterozygous ELANE mutation.2013

    • Author(s)
      Hiramoto T
    • Journal Title

      Proc Natl Acad Sci USA

      Volume: 110 Issue: 8 Pages: 3023-3028

    • DOI

      10.1073/pnas.1217039110

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591161, KAKENHI-PROJECT-23310137, KAKENHI-PROJECT-23650150, KAKENHI-PROJECT-23790126, KAKENHI-PROJECT-24390257, KAKENHI-PROJECT-24390272, KAKENHI-PROJECT-24659489, KAKENHI-PROJECT-25293231, KAKENHI-PLANNED-23106004
  • [Journal Article] Wnt5a Signaling Mediates Biliary Differentiation of Fetal Hepatic Stem/Progenitor Cells2013

    • Author(s)
      Kakinuma S, Kiyohashi K, Kamiya A, Sakamoto N, Nitta S, Yamanaka H, YoshinoK, Fujiki J, Murakawa M, Kusano-Kitazume A, Shimizu H, Okamoto R, Azuma S, Nakagawa M, Asahina Y, Tanimizu N, Kikuchi A, Nakauchi H, and *WatanabeM
    • Journal Title

      Hepatology

      Volume: (in press) Issue: 6 Pages: 2502-2513

    • DOI

      10.1002/hep.26293

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590831, KAKENHI-ORGANIZER-23112001, KAKENHI-PLANNED-23112004, KAKENHI-PROJECT-23689040, KAKENHI-PROJECT-23790777, KAKENHI-PUBLICLY-24112505, KAKENHI-PUBLICLY-24112519, KAKENHI-PROJECT-24390304, KAKENHI-PROJECT-24590957, KAKENHI-PROJECT-24590958, KAKENHI-PROJECT-24590959, KAKENHI-PROJECT-24590960, KAKENHI-PROJECT-24659359, KAKENHI-PROJECT-25250018, KAKENHI-PROJECT-25293169, KAKENHI-PROJECT-25293289, KAKENHI-PROJECT-25460271, KAKENHI-PROJECT-25670366, KAKENHI-PROJECT-25860522, KAKENHI-PLANNED-23102003, KAKENHI-PLANNED-23106004
  • [Journal Article] Recurrent mutations in multiple components of the cohesin complex in myeloid neoplasms.2013

    • Author(s)
      Kon A, Yoshida K
    • Journal Title

      Nature Genet.

      Volume: 45 Issue: 10 Pages: 1232-1237

    • DOI

      10.1038/ng.2731

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12J04216, KAKENHI-PLANNED-22134003, KAKENHI-PLANNED-22134006, KAKENHI-PROJECT-22221009, KAKENHI-PLANNED-23106004, KAKENHI-PROJECT-23249052, KAKENHI-PROJECT-24221011, KAKENHI-PROJECT-24249056, KAKENHI-PROJECT-24390242, KAKENHI-PROJECT-24659458, KAKENHI-PROJECT-25290065, KAKENHI-PROJECT-25461408, KAKENHI-PROJECT-25670446, KAKENHI-PROJECT-25670471, KAKENHI-PROJECT-25670489, KAKENHI-PROJECT-25730173, KAKENHI-PROJECT-25860521
  • [Journal Article] Role of SOX17 in hematopoietic development from human embryonic stem cells.2013

    • Author(s)
      Nakajima-Takagi Y, Osawa M, Oshima M, Takagi H, Miyagi S, Endoh M, Endo TA, Takayama N, Eto K, Toyoda T, Koseki H, Nakauchi H, Iwama A.
    • Journal Title

      Blood.

      Volume: 121 Issue: 3 Pages: 447-58

    • DOI

      10.1182/blood-2012-05-431403

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23249015, KAKENHI-PROJECT-23650622, KAKENHI-PROJECT-23791071, KAKENHI-PROJECT-23791154, KAKENHI-PROJECT-24249056, KAKENHI-PROJECT-24300160, KAKENHI-PROJECT-24591381, KAKENHI-PLANNED-23106004, KAKENHI-PUBLICLY-23130502, KAKENHI-PUBLICLY-24116711
  • [Journal Article] Top-down motif engineering of a cytokine receptor for directing ex vivo expansion of hematopoietic stem cells.2013

    • Author(s)
      Saka K, Kawahara M, Teng J, Otsu M, Nakauchi H, Nagamune T.
    • Journal Title

      J Biotechnol.

      Volume: 168 Issue: 4 Pages: 659-65

    • DOI

      10.1016/j.jbiotec.2013.09.012

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23106004, KAKENHI-PROJECT-24249056, KAKENHI-PROJECT-24360337, KAKENHI-PROJECT-24659127, KAKENHI-PROJECT-25670471, KAKENHI-PROJECT-25670489
  • [Journal Article] Two differential flows in a bioreactor promoted platelet generation from human pluripotent stem cell-derived megakaryocytes.2013

    • Author(s)
      Nakagawa Y, Nakamura S, Nakajima M, Endo H, Dohda T, Takayama N, Nakauchi H, Arai F, Fukuda T, Eto K.
    • Journal Title

      Exp Hematology.

      Volume: 41 Issue: 8 Pages: 742-8

    • DOI

      10.1016/j.exphem.2013.04.007

    • NAID

      120005312061

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23106004, KAKENHI-PROJECT-24249056, KAKENHI-PROJECT-24300160
  • [Journal Article] CAMT-iPS Cells Exhibiting Defective MPL Signaling Dysregulate Megakaryopoiesis and Erythropoiesis.2013

    • Author(s)
      Shinji Hirata, Naoya Takayama,Ryoko Jono-Ohnishi, Hiroshi Endo, Sou Nakamura, Takeaki Dohda, Masanori Nishi, Yuhei Hamazaki, Ei-ichi Ishii, Shin Kaneko, Makoto Otsu, Hiromitsu Nakauchi, Shinji Kunishima, and Koji Eto.
    • Journal Title

      J Clin Invest.

      Volume: 123 Issue: 9 Pages: 3802-14

    • DOI

      10.1172/jci64721

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23106004, KAKENHI-PROJECT-23591413, KAKENHI-PROJECT-23591429, KAKENHI-PROJECT-24249056, KAKENHI-PROJECT-24300160, KAKENHI-PROJECT-24659127, KAKENHI-PROJECT-25670471, KAKENHI-PROJECT-25670489
  • [Journal Article] Generation of Col2a1-EGFP iPS cells for monitoring chondrogenic differentiation2013

    • Author(s)
      Saito T, Yano F, Mori D, Ohba S, Hojo H, Otsu M, Eto K, Nakauchi H, Tanaka S, Chung UI, Kawaguchi H
    • Journal Title

      PLoS One

      Volume: 16;8(9) Issue: 9 Pages: e74137-e74137

    • DOI

      10.1371/journal.pone.0074137

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22689052, KAKENHI-PLANNED-23106004, KAKENHI-PROJECT-23390358, KAKENHI-PROJECT-23390459, KAKENHI-PROJECT-23689065, KAKENHI-PROJECT-24249056, KAKENHI-PROJECT-24592253, KAKENHI-PROJECT-24659665, KAKENHI-PROJECT-25253087, KAKENHI-PROJECT-25293316, KAKENHI-PROJECT-25670471, KAKENHI-PROJECT-25670489, KAKENHI-PROJECT-25670634, KAKENHI-PROJECT-25670851, KAKENHI-PROJECT-25713052
  • [Journal Article] Integrin αvβ3 regulates thrombopoietin-mediated maintenance of hematopoietic stem cells2012

    • Author(s)
      Umemoto T, Yamato M, Ishihara J, Shiratsuchi Y, Utsumi M, Morita Y, Tsukui H, Terasawa M, Shibata T, Nishida K, Kobayashi Y, Petrich BG, Nakauchi H, Eto K, Okano T
    • Journal Title

      Blood

      Volume: 119(1) Issue: 1 Pages: 83-94

    • DOI

      10.1182/blood-2011-02-335430

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21300160, KAKENHI-PROJECT-21390321, KAKENHI-PLANNED-23106004, KAKENHI-PLANNED-23106009, KAKENHI-PROJECT-23659514
  • [Journal Article] Rapid T-cell chimerism switch and memory T-cell expansion are associated with pre-engraftment immune reaction early after cord blood transplantation.2012

    • Author(s)
      Matsuno N, Yamamoto H, Watanabe N, Uchida N, Ota H, Nishida A, Ikebe T, Ishiwata K, Nakano N, Tsuji M, Asano-Mori Y, Izutsu K, Masuoka K, Wake A, Yoneyama A, Nakauchi H, Taniguchi S.
    • Journal Title

      Br J Haematol

      Volume: 160 Issue: 2 Pages: 255-8

    • DOI

      10.1111/bjh.12097

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249056, KAKENHI-PLANNED-23106004
  • [Journal Article] Enrichment and clonal culture of hepatic stem/progenitor cells during mouse liver development.2012

    • Author(s)
      Kamiya A, Nakauchi H.
    • Journal Title

      Methods Mol Biol

      Volume: 945 Pages: 273-86

    • DOI

      10.1007/978-1-62703-125-7_16

    • ISBN
      9781627031240, 9781627031257
    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23106004
  • [Journal Article] Identification of rat Rosa26 locus enables generation of knock-in rat lines ubiquitously expressing tdTomato2012

    • Author(s)
      Kobayashi T
    • Journal Title

      Stem Cell Development

      Volume: 21 Issue: 16 Pages: 2981-2986

    • DOI

      10.1089/scd.2012.0065

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22300147, KAKENHI-PLANNED-23106004
  • [Journal Article] Lethal myelofibrosis induced by Bmi1-deficient hematopoietic cells unveils a tumor suppressor function of the polycomb group genes2012

    • Author(s)
      Oguro H, Yuan J, Tanaka S, Miyagi S, Mochizuki-Kashio M, Ichikawa H, Yamazaki S, Koseki H, Nakauchi H, Iwama A
    • Journal Title

      J Exp Med

      Volume: 209 Pages: 445-54

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659058
  • [Journal Article] Stem cell therapy: an exercise in patience and prudence.2012

    • Author(s)
      Lin HT, Otsu M, Nakauchi H.
    • Journal Title

      Philos Trans R Soc Lond B Biol Sci

      Volume: 5 Issue: 1609 Pages: 20110334-20110334

    • DOI

      10.1098/rstb.2011.0334

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249056, KAKENHI-PROJECT-24659127, KAKENHI-PROJECT-24659489, KAKENHI-PROJECT-25670471, KAKENHI-PROJECT-25670489, KAKENHI-PLANNED-23106004
  • [Journal Article] Sal-like protein 4 (SALL4), a stem cell biomarker in liver cancers.2012

    • Author(s)
      Oikawa T, Kamiya A*, Zeniya M, Chikada H, Hyuck AD, Yamazaki Y, Wauthier E, Tajiri H, Miller LD, Wang XW, Reid LM*, Nakauchi H*.
    • Journal Title

      Hepatology

      Volume: in press Issue: 4 Pages: 1469-83

    • DOI

      10.1002/hep.26159

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23689040, KAKENHI-PLANNED-23106004, KAKENHI-PUBLICLY-24112505
  • [Journal Article] Ability of tetraploid rat blastocysts to support fetal development after complementation with embryonic stem cells2012

    • Author(s)
      Hirabayashi M
    • Journal Title

      Molecular Reproduction and Development

      Volume: 79 Issue: 6 Pages: 402-412

    • DOI

      10.1002/mrd.22043

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22300147, KAKENHI-PROJECT-23700507, KAKENHI-PLANNED-23106004
  • [Journal Article] Lethal myelofibrosis induced by Bmil-deficient hematopoietic cells unveils a tumor suppressor function of the polycomb group genes2012

    • Author(s)
      Oguro H, Yuan J, Tanaka S, Miyagi S, Mochizuki-Kashio M, Ichikawa H, Yamazaki S, Koseki H, Nakauchi H, Iwama A
    • Journal Title

      J Exp Med

      Volume: 209 Pages: 445-54

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249059
  • [Journal Article] A Differentiation Checkpoint Limits Hematopoietic Stem Cell Self-Renewal in Response to DNA Damage2012

    • Author(s)
      Wang J, Sun Q, Morita Y, Jiang H, Gros A, Lechel A, Hildner K, Guachalla LM, Gompf A, Hartmann D, Schambach A, Wuestefeld T, Dauch D, Schrezenmeier H, Hofmann WK, Nakauchi H, Ju Z, Kestler HA, Zender L, Rudolph KL.
    • Journal Title

      Cell

      Volume: 148 Pages: 1001-1014

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249059
  • [Journal Article] A Differentiation Checkpoint Limits Hematopoietic Stem Cell Self-Renewal in Response to DNA Damage2012

    • Author(s)
      Wang J, Sun Q, Morita Y, Jiang H, Gross A, Lechel A, Hildner K, Guachalla LM, Gompf A, Hartmann D, Schambach A, Wuestefeld T, Dauch D, Schrezenmeier H, Hofmann WK, Nakauchi H, Ju Z, Kestler HA, Zender L, Rudolph KL
    • Journal Title

      Cell

      Volume: 148 Issue: 5 Pages: 1001-1014

    • DOI

      10.1016/j.cell.2012.01.040

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659058, KAKENHI-PLANNED-23106004
  • [Journal Article] Development of an All-in-One Inducible Lentiviral Vector for Gene Specific Analysis of Reprogramming.2012

    • Author(s)
      Yamaguchi T, Hamanaka S, Kamiya A, Okabe M, Kawarai M, Wakiyama Y, Umino A, Hayama T, Sato H, Lee YS, Kato-Itoh M, Masaki H, Kobayashi T, Yamazaki S, Nakauchi H.
    • Journal Title

      PLoS One.

      Volume: 7 Issue: 7 Pages: e41007-e41007

    • DOI

      10.1371/journal.pone.0041007

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23689040, KAKENHI-PROJECT-23700507, KAKENHI-PROJECT-24249056, KAKENHI-PLANNED-23106004, KAKENHI-PUBLICLY-24112505
  • [Journal Article] Plasmin inhibitor reduces lymphoid tumor growth by suppressing matrixmetallproteinase-9 dependent CD11b+/F4/80+ myeloid cell recruitment2012

    • Author(s)
      Ishihara M, Heissig B, Nishida C, Rosenkvist J, Tashiro Y, Ohki M, Wanaka K, Tsuda Y, Okada Y, Nakauchi H, Hattori K
    • Journal Title

      Leukemia

      Volume: 26 Issue: 2 Pages: 332-339

    • DOI

      10.1038/leu.2011.203

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-11J00480, KAKENHI-PROJECT-21249059, KAKENHI-PROJECT-21591193, KAKENHI-PROJECT-21591234, KAKENHI-PUBLICLY-22019006, KAKENHI-PUBLICLY-22021013, KAKENHI-PLANNED-22112007, KAKENHI-PROJECT-22240089, KAKENHI-PROJECT-22590111, KAKENHI-PUBLICLY-23013009, KAKENHI-PROJECT-23591371, KAKENHI-PROJECT-23701090, KAKENHI-PUBLICLY-22117506
  • [Journal Article] MT1-MMP plays a critical role in henatopoiesis by regulating HIF-mediated chemo-/cytokine gene transcription within niche cells.2012

    • Author(s)
      Chiemi Nishida, Kaori Kusubata, Yoshihiko Tashiro, Ismael Gritli, Aki Sato, Makiko Ohki-Koizumi, Yohei Morita, Makoto Nagano, Takeharu Sakamoto, Naohiko Koshikawa, Takahiro Kuchimaru, Shinae Kizaka-Kondoh, Motoharu Seiki, Hiromitsu Nakauchi, Beate Heissig, and Koichi Hattori.
    • Journal Title

      Blood

      Volume: 119 Issue: 23 Pages: 5404-5416

    • DOI

      10.1182/blood-2011-11-390849

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-11J00480, KAKENHI-PROJECT-12J04973, KAKENHI-PROJECT-22591762, KAKENHI-PUBLICLY-23013009, KAKENHI-PROJECT-23591371, KAKENHI-PROJECT-24249056, KAKENHI-PROJECT-24591313, KAKENHI-PROJECT-24591382, KAKENHI-PLANNED-22112007, KAKENHI-PLANNED-22112009, KAKENHI-PLANNED-23106004, KAKENHI-PUBLICLY-23112505
  • [Journal Article] In vivo imaging visualizes discoid platelet aggregations without endothelium disruption and implicates contribution of inflammatory cytokine and integrin signaling2012

    • Author(s)
      Nishimura S, Manabe I, Nagasaki M, Kakuta S, Iwakura Y, Takayama N, Ooehara J, Otsu M, Kamiya A, Petrich B, Urano T, Kadono T, Sato S, Aiba A, Yamashita H, Sugiura S, Kadowaki T, Nakauchi H, Eto K, Nagai R
    • Journal Title

      Blood

      Volume: 119

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23106004
  • [Journal Article] Highly efficient generation of definitive endoderm lineage from human induced pluripotent stem cells2012

    • Author(s)
      Sekine K
    • Journal Title

      Transplant Proc

      Volume: 44(4) Issue: 4 Pages: 1127-1129

    • DOI

      10.1016/j.transproceed.2012.03.001

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249071, KAKENHI-PROJECT-23659620, KAKENHI-PROJECT-23689040, KAKENHI-PROJECT-24390305, KAKENHI-PROJECT-24659593, KAKENHI-PROJECT-24659785, KAKENHI-PROJECT-24689052, KAKENHI-PLANNED-23106004, KAKENHI-PUBLICLY-24106510, KAKENHI-PUBLICLY-24112505
  • [Journal Article] Distinct B-cell lineage commitment distinguishes adult bone marrow hematopoietic stem cells2012

    • Author(s)
      Ghosn EE, Yamamoto R, Hamanaka S, Yang Y, Herzenberg LA, Nakauchi H, Herzenberg LA.
    • Journal Title

      Proc Natl Acad Sci U S A.

      Volume: 109 Issue: 14 Pages: 5394-8

    • DOI

      10.1073/pnas.1121632109

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23791075, KAKENHI-PLANNED-23106004
  • [Journal Article] Lethal myelofibrosis induced by Bmi1-deficient hematopoietic cells unveils a tumor suppressor function of the polycomb group genes2012

    • Author(s)
      Oguro H, Yuan J, Tanaka S, Miyagi S, Mochizuki-Kashio M, Ichikawa H, Yamazaki S, Koseki H, Nakauchi H, Iwama A
    • Journal Title

      J Exp Med

      Volume: 209 Pages: 445-54

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23106004
  • [Journal Article] Generation of induced pluripotent stem cells from primary chronic myelogenous leukemia2012

    • Author(s)
      Keiki Kumano
    • Journal Title

      BLOOD

      Volume: 119 Issue: 26 Pages: 6234-6242

    • DOI

      10.1182/blood-2011-07-367441

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591026, KAKENHI-PROJECT-23591369, KAKENHI-PROJECT-23650622, KAKENHI-PROJECT-23790775, KAKENHI-PROJECT-23791154, KAKENHI-PROJECT-24221011, KAKENHI-PROJECT-24249055, KAKENHI-PROJECT-24249056, KAKENHI-PROJECT-24300160, KAKENHI-PROJECT-24659127, KAKENHI-PROJECT-24659457, KAKENHI-PROJECT-24659489, KAKENHI-PLANNED-23106004, KAKENHI-PUBLICLY-23112504, KAKENHI-PUBLICLY-23130503
  • [Journal Article] Generation of kidney from pluripotent stem cells via blastocyst complementation.2012

    • Author(s)
      Usui J, et al.
    • Journal Title

      Am J Pathol

      Volume: 180 Issue: 6 Pages: 2417-2426

    • DOI

      10.1016/j.ajpath.2012.03.007

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790794, KAKENHI-PROJECT-23659446, KAKENHI-PLANNED-23106004
  • [Journal Article] Inhibition of PAI-1 induces neutrophil-driven neoangiogenesis and promotes tissue regeneration via production of angiocrine factors in mice2012

    • Author(s)
      Yoshihiko Tashiro, Chiemi Nishida, Kaori Sato-Kusubata, Makiko Ohki-Koizumi, Makoto Ishihara, Aki Sato, Ismael Gritli, Hiromitsu Komiyama, Yayoi Sato, Takashi Dan, Toshio Miyata, Ko Okumura, Yuichi Tomiki, Kazuhiro Sakamoto, Hiromitsu Nakauchi, Beate Heissig, and Koichi Hattori.
    • Journal Title

      Blood

      Volume: 119 Issue: 26 Pages: 6382-6393

    • DOI

      10.1182/blood-2011-12-399659

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-11J00480, KAKENHI-PUBLICLY-23013009, KAKENHI-PROJECT-23390260, KAKENHI-PROJECT-23591371, KAKENHI-PROJECT-23790878, KAKENHI-PROJECT-23791501, KAKENHI-PROJECT-24249033, KAKENHI-PROJECT-24249056, KAKENHI-PROJECT-24591382, KAKENHI-PROJECT-24591983, KAKENHI-ORGANIZER-22112001, KAKENHI-PLANNED-22112007, KAKENHI-PLANNED-23106004
  • [Journal Article] Bmil confers resistance to oxidative stress on hematopoietic stem cells.2012

    • Author(s)
      Nakamura S, Oshima M, Yuan J, Saray a A, Miyagi S, Konuma T, Yamazaki S, Osawa M, Nakauchi H, Koseki H, Iwama A.
    • Journal Title

      PLoS One

      Volume: 7(5) Issue: 5 Pages: e36209-e36209

    • DOI

      10.1371/journal.pone.0036209

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-10J03550, KAKENHI-PROJECT-23249015, KAKENHI-PROJECT-23791071, KAKENHI-PROJECT-24249056, KAKENHI-PLANNED-23106004
  • [Journal Article] Lethal myelofibrosis induced by Bmi1-deficient hematopoietic cells unveils a tumor suppressor function of the polycomb group genes2012

    • Author(s)
      Oguro H, Yuan J, Tanaka S, Miyagi S, Mochizuki-Kashio M, Ichikawa H, Yamazaki S, Koseki H, Nakauchi H, Iwama A.
    • Journal Title

      J Exp Med

      Volume: 209 Pages: 445-54

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249059
  • [Journal Article] Development of defective and persistent sendai virus vector : a unique gene delivery/expression system ideal for cell reprogramming.2011

    • Author(s)
      Nishimura K, Sano M, Ohtaka M, Furuta B, Umemura Y, Nakajima Y, Ikehara T, Kobayashi T, Segawa H, Takayasu S, Sato H, Motomura K, Uchida E, Kanayasu-Toyoda T, Asashima M, Nakauchi H, Yamaguchi T, Nakanishi M.
    • Journal Title

      J Biol Chem

      Volume: 11 Pages: 4760-71

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659058
  • [Journal Article] Hair follicle stem cells provide a functional niche for melanocyte stem cells2011

    • Author(s)
      Tanimura S, Tadokoro Y, Inomata K, Binh NT, Nishie W, Yamazaki S, Nakauchi H, Tanaka Y, McMillan JR, Sawamura D, Yancey K, Shimizu H, Nishimura EK
    • Journal Title

      Cell Stem Cell

      Volume: 8 Pages: 177-87

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249059
  • [Journal Article] Ex vivo expansion of human hematopoietic stem cells by garcinol, a potent inhibitor of histone acetyltransferase2011

    • Author(s)
      Nishino T, Wang C, Mochizuki-Kashio M, Osawa M, Nakauchi H, Iwama A.
    • Journal Title

      PLoS One

      Volume: 6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249059
  • [Journal Article] Prospective isolation and characterization of bi-potent progenitor cells in early mouse liver development2011

    • Author(s)
      Okada K, Kamiya A, Ito K, Yanagida A, Ito H, Kondou H, Nishina H, Nakauchi H
    • Journal Title

      Cells Dev

      Volume: (Epub ahead of print) Issue: 7 Pages: 1124-33

    • DOI

      10.1089/scd.2011.0229

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23106004, KAKENHI-PROJECT-23390018, KAKENHI-PROJECT-23689040, KAKENHI-PROJECT-24659030, KAKENHI-PUBLICLY-23118510
  • [Journal Article] Homeostasis of hematopoietic stem cells regulated by the myeloproliferative disease associated-gene product Lnk/Sh2b3 via Bcl-xL2011

    • Author(s)
      Suzuki N, Yamazaki S, Ema H, Yamaguchi T, Nakauchi H, Takaki S.
    • Journal Title

      Exp Hematol

      Volume: 40 Pages: 166-74

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249059
  • [Journal Article] In vitro expansion and functional recovery of mature hepatocytes from mouse adult liver2011

    • Author(s)
      Ito H, Kamiya A, Ito K, Yanagida A, Okada K, Nakauchi H
    • Journal Title

      Liver Int

      Volume: 32 Issue: 4 Pages: 592-601

    • DOI

      10.1111/j.1478-3231.2011.02741.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23106004, KAKENHI-PROJECT-23689040
  • [Journal Article] Frequent pathway mutations of splicing machinery in myelodysplasia2011

    • Author(s)
      Kenichi Yoshida
    • Journal Title

      Nature

      Volume: 478 Issue: 7367 Pages: 64-69

    • DOI

      10.1038/nature10496

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22130002, KAKENHI-PLANNED-22134004, KAKENHI-PROJECT-22390191, KAKENHI-PROJECT-22659058, KAKENHI-PROJECT-22790895, KAKENHI-PLANNED-23106004, KAKENHI-PUBLICLY-23118503, KAKENHI-PROJECT-23390269, KAKENHI-PROJECT-23659482, KAKENHI-PROJECT-23659533, KAKENHI-PROJECT-23791068, KAKENHI-PROJECT-23791075
  • [Journal Article] Ex vivo expansion of human hematopoietic stem cells by garcinol, a potent inhibitor of histone acetyltransferase2011

    • Author(s)
      Nishino T, Wang C, Mochizuki-Kashio M, Osawa M, Nakauchi H, Iwama A
    • Journal Title

      PLoS One

      Volume: 6 Issue: 9 Pages: e24298-e24298

    • DOI

      10.1371/journal.pone.0024298

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249059, KAKENHI-PROJECT-21390289, KAKENHI-PROJECT-22790898, KAKENHI-PUBLICLY-23130502
  • [Journal Article] Nonmyelinating Schwann cells maintain hematopoietic stem cell hibernation in the bone marrow niche2011

    • Author(s)
      Yamazaki S, Ema H, Karlsson G, Yamaguchi T, Miyoshi H, Shioda S, Taketo MM, Karlsson S, Iwama A, Nakauchi H.
    • Journal Title

      Cell

      Volume: 147 Pages: 1146-58

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249059
  • [Journal Article] Minimum requirement of donor cells to reduce the glycolipid storage following bone marrow transplantation in a murine model of Fabry disease2011

    • Author(s)
      Yokoi T, Kobayashi H, Shimada Y, Higuchi T, Eto Y, Ishige N, Kitagawa T, Otsu M, Nakauchi H, Ida H, Ohashi T
    • Journal Title

      J Gene Med

      Volume: 13 Pages: 262-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23106004
  • [Journal Article] Nonmyelinating Schwann cells maintain hematopoietic stem cell hibernation in the bone marrow niche2011

    • Author(s)
      Yamazaki S, Ema H, Karlsson G, Yamaguchi T, Miyoshi H, Shioda S, Taketo MM, Karlsson S, Iwama A, Nakauchi H
    • Journal Title

      Cell

      Volume: 147 Issue: 5 Pages: 1146-1158

    • DOI

      10.1016/j.cell.2011.09.053

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229005, KAKENHI-PUBLICLY-22019005, KAKENHI-PROJECT-22591029, KAKENHI-PROJECT-22659058, KAKENHI-PLANNED-23106004, KAKENHI-PUBLICLY-23118505, KAKENHI-PUBLICLY-23130502
  • [Journal Article] Development of defective and persistent sendai virus vector : a unique gene delivery/expression system ideal for cell reprogramming2011

    • Author(s)
      Nishimura K, Sano M, Ohtaka M, Furuta B, Umemura Y, Nakajima Y, Ikehara Y, Kobayashi T, Segawa H, Takayasu S, Sato H, Motomura K, Uchida E, Kanayasu-Toyoda T, Asashima M, Nakauchi H, Yamaguchi T, Nakanishi M
    • Journal Title

      J Biol Chem

      Volume: 11 Pages: 4760-4760

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249059
  • [Journal Article] Functional characterization of hematopoietic stem cells in the spleen2011

    • Author(s)
      Morita Y, Iseki A, Okamura S, Suzuki S, Nakauchi H, Ema H
    • Journal Title

      Exp Hematol

      Volume: 39 Pages: 351-359

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249059
  • [Journal Article] Generation of germline-competent rat induced pluripotent stem cells2011

    • Author(s)
      Hamanaka S
    • Journal Title

      PLoS ONE

      Volume: 6 Issue: 7 Pages: e22008-e22008

    • DOI

      10.1371/journal.pone.0022008

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22300147, KAKENHI-PROJECT-22659058, KAKENHI-PROJECT-23700507
  • [Journal Article] Serine/Threonine kinase Melk regulates proliferation and glial differentiation of retinal progenitor cells2011

    • Author(s)
      Saito R, Nakauchi H, Watanabe S
    • Journal Title

      Cancer Sci

      Volume: 103 Issue: 1 Pages: 42-9

    • DOI

      10.1111/j.1349-7006.2011.02104.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23106004
  • [Journal Article] Integrin-αvβ3 regulates thrombopoietin-mediated maintenance of hematopoietic stem cells2011

    • Author(s)
      Umemoto T, Yamato M, Ishihara J, Shiratsuchi Y, Utsumi M, Morita Y, Tsukui H, Terasawa M, Shibata T, Nishida K, Kobayashi Y, Petrich BG, Nakauchi H, Eto K, Okano T.
    • Journal Title

      Blood

      Volume: 119 Pages: 83-94

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249059
  • [Journal Article] Growth promotion of genetically modified hematopoietic progenitors using an antibody/c-Mpl chimera2011

    • Author(s)
      Kawahara M, Chen J, Sogo T, Teng J, Otsu M, Onodera M, Nakauchi H, Ueda H, Nagamune T
    • Journal Title

      Cytokine

      Volume: 55 Pages: 402-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23106004
  • [Journal Article] Functional characterization of hematopoietic stem cells in the spleen.2011

    • Author(s)
      Morita Y, Iseki A, Okamura S, Suzuki S, Nakauchi H, Ema H.
    • Journal Title

      Exp Hematol

      Volume: 39 Pages: 351-359

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249059
  • [Journal Article] Characterization of the ICSI-mediated gene transfer method in the production of transgenic pigs2011

    • Author(s)
      Umeyama K, Saito H, Kurome M, Matsunari H, Watanabe M, Nakauchi H, Nagashima H
    • Journal Title

      Reprod Dev

      Volume: 79 Pages: 218-28

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23106004
  • [Journal Article] Potential usefulness of human iPS cells on the generation of platelets2011

    • Author(s)
      Takayama N, Eto K, Nakauchi H
    • Journal Title

      Nihon Rinsho

      Volume: 69(12) Pages: 2161-2165

    • NAID

      40019080133

    • Data Source
      KAKENHI-PLANNED-23106004
  • [Journal Article] Development of defective and persistent sendai virus vector : a unique genedelivery/expression system ideal for cell reprogramming.2011

    • Author(s)
      Nishimura K, Sano M, OhtakaM, Furuta B, Umemura Y, Nakajima Y, Ikehara Y, Kobayashi T, Segawa H, Takayasu S, Sato H, MotomuraK, Uchida E, Kanayasu-ToyodaT, Asashima M, Nakauchi H, Yamaguchi T, Nakanishi M.
    • Journal Title

      JBiol Chem

      Volume: 286 Pages: 4760-71

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249059
  • [Journal Article] Generation of rat pancreas in mouse by interspecific blastocyst injection of pluripotent stem cells2010

    • Author(s)
      Kobayashi T
    • Journal Title

      Cell

      Volume: 142 Issue: 5 Pages: 787-799

    • DOI

      10.1016/j.cell.2010.07.039

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22300147, KAKENHI-PROJECT-22659058
  • [Journal Article] Gain-of-function c-CBL mutations associated with uniparental disomy of 11q in myeloid neoplasms.2010

    • Author(s)
      Ogawa S, Sanada M, Shin LY, Suzuki T, Otsu M, Nakauchi H, Koeffler HP.
    • Journal Title

      Cell Cycle. 9(6)(In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249059
  • [Journal Article] Reprogramming adult hematopoietic cells.2010

    • Author(s)
      Kaneko S, Otsu M, Nakauchi H.
    • Journal Title

      Curr Opin Hematol

      Volume: 17 Pages: 271-275

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249059
  • [Journal Article] Tissue type plasminogen activator regulates myeloid-cell dependent neoangiogenesis during tissue regeneration2010

    • Author(s)
      Ohki M, Ohki Y, Ishihara M, Nishida C, Tashiro Y, Akiyama H, Komiyama H, Lund LR, Nitta A, Yamada K, Zhu Z, Ogawa H, Yagita H, Okumura K, Nakauchi H, Werb Z, Heissig B, Hattori K
    • Journal Title

      Blood

      Volume: 115 Pages: 4302-12

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249059
  • [Journal Article] Downregulation of ZEB1 and overexpression of Smad7 contribute to resistance to TGF-betal-mediated growth suppression in adult T-cell leukemia/lymphoma.2010

    • Author(s)
      Nakahata S, Yamazaki S, Nakauchi H, Morishita K.
    • Journal Title

      Oncogene

      Volume: 29 Pages: 4157-69

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249059
  • [Journal Article] Tissue type plasminogen activator regulates myeloid-cell dependent neoangiogenesis during tissue regeneration.2010

    • Author(s)
      Ohki M, Ohki Y, Ishihara M, Nishida C, Tashiro Y, Akiyama H, Komiyama H, Lund LR, Nitta A, Yamada K, Zhu Z, Ogawa H, Yagita H, Okumura K, Nakauchi H, Werb Z, Heissig B, Hattori K.
    • Journal Title

      Blood 6(3)(In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249059
  • [Journal Article] Reprogramming adult hematopoietic cells2010

    • Author(s)
      Kaneko S, Otsu M, Nakauchi H
    • Journal Title

      Opin Hematol

      Volume: 17 Pages: 271-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249059
  • [Journal Article] Rat transgenesis via embryonic stem cells electroporated with the Kusabira-orange gene2010

    • Author(s)
      Hirabayashi M, Kato M, Sanbo M, Kobayashi T, Hochi S, Nakauchi H.
    • Journal Title

      Mol Reprod Dev

      Volume: 77 Pages: 474-474

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249059
  • [Journal Article] Lnk regulates integrin alphallbbeta3 outside-in signaling in mouse platelets, leading to stabilization of thrombus development in vivo.2010

    • Author(s)
      Takizawa H, Nishimura S, Takayama N, Oda A, Nishikii H, Morita Y, Kakinuma S, Yamazaki S, Okamura S, Tamura N, Goto S, Sawaguchi A, Manabe I, Takatsu K, NakauchiH, Takaki S, Eto K.
    • Journal Title

      J Cln Invest

      Volume: 120 Pages: 179-190

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249059
  • [Journal Article] Heterogeneity and hierarchy within the most primitive hematopoietic stem cell compartment2010

    • Author(s)
      Morita Y, Ema H, Nakauchi H
    • Journal Title

      J Exp Med

      Volume: 207 Pages: 1173-82

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249059
  • [Journal Article] Lnk regulates integrin alphaIIbbeta3 outside-in signaling in mouse platelets, leading to stabilization of thrombus development in vivo.2010

    • Author(s)
      Takizawa H, Nishimura S, Takayama N, Oda A, Nishikii H, Morita Y, Kakinuma S, Yamazaki S, Okamura S, Tamura N, Goto S, Sawaguchi A, Manabe I, Takatsu K, Nakauchi H, Takaki S, Eto K.
    • Journal Title

      J Clin Invest. 120

      Pages: 179-90

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249059
  • [Journal Article] Establishment of rat embryonic stem cell lines that can participate in germline chimerae at high efficiency.2010

    • Author(s)
      Hirabayashi M, Kato M, Kobayashi T, Sanbo M, Yagi T, Hochi S, Nakauchi H.
    • Journal Title

      Mol Reprod Dev. Nov 6(In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249059
  • [Journal Article] Deregulated intracellular signaling by mutated c-CBL in myeloid neoplasms.2010

    • Author(s)
      Ogawa S, Shih LY, Suzuki T, Otsu M, Nakauchi H, KoefflerHP, Sanada M.
    • Journal Title

      Clin Cancer Res

      Volume: 16 Pages: 3825-3831

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249059
  • [Journal Article] Transient activation of c-MYC expression is critical for efficient platelet generation from human induced pluripotent stem cells.2010

    • Author(s)
      Takayama N, Nishimura S, Nakamura S, Shimizu T, Ohnishi R, Endo H, Yamaguchi T, Otsu M, Nishimura K, Nakanishi M, Sawaguchi A, Nagai R, Takahashi K, Yamanaka S, Nakauchi H, Eto K.
    • Journal Title

      J Exp Med

      Volume: 20 Pages: 2817-30

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659058
  • [Journal Article] Poised lineage specification in multipotential hematopoietic stem and progenitor cells by the polycomb protein Bmil.2010

    • Author(s)
      Oguro H, Yuan J, Ichikawa H, Ikawa T, Yamazaki S, Kawamoto H, Nakauchi H, Iwama A.
    • Journal Title

      Cell Stem Cell

      Volume: 6 Pages: 279-286

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249059
  • [Journal Article] Gain-of-function c-CBL mutations associated with uniparental disomy of 11q in myeloid neoplasms.2010

    • Author(s)
      Ogawa S, Sanada M, Shih LY, Suzuki T, Otsu M, Nakauchi H, Koeffler HP.
    • Journal Title

      Cell Cycle

      Volume: 9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249059
  • [Journal Article] Deregulated intracellular signaling by mutated c-CBL in myeloid neoplasms2010

    • Author(s)
      Ogawa S, Shih LY, Suzuki T, Otsu M, Nakauchi H, Koeffler HP, Sanada M
    • Journal Title

      Clin Cancer Res

      Volume: 16 Pages: 3825-31

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249059
  • [Journal Article] Hair follicle stem cells provide a functional niche for melanocyte stem cells.2010

    • Author(s)
      Tanimura S, Tadokoro Y, Inomata K, Binh NT, Nishie W, Yamazaki S, Nakauchi H, Tanaka Y, McMillan JR, Sawamura D, Yancey K, ShimizuH, Nishimura EK.
    • Journal Title

      Cell Stem Cell

      Volume: 4 Pages: 177-87

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249059
  • [Journal Article] Reprogramming adult hematopoietic cells2010

    • Author(s)
      Kaneko S, Otsu M, Nakauchi H
    • Journal Title

      Curr Opin Hematol

      Volume: 17 Issue: 4 Pages: 271-5

    • DOI

      10.1097/moh.0b013e32833a25ee

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659058
  • [Journal Article] FET family proto-oncogene Fus contributes to self-renewal of hematopoietic stem cel.2010

    • Author(s)
      Sugawara T, Oguro H, NegishiM, Morita Y, Ichikawa H, IsekiT, Yokosuka 0, Nakauchi H, Iwama A.
    • Journal Title

      Exp Hematol

      Volume: 38 Pages: 696-706

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249059
  • [Journal Article] Mice lacking Dok-1, Dok-2, and Dok-3 succumb to aggressive histiocytic sarcoma.2010

    • Author(s)
      Mashima R, Honda K, Yang Y, Morita Y, Inoue A, Arimura S, Nishina H, Ema H, Nakauchi H, Seed B, Oda H, Yamanashi Y.
    • Journal Title

      Lab Invest

      Volume: 17 Pages: 271-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249059
  • [Journal Article] Generation of rat pancreas in mouse by interspecific blastocyst injection of pluripotent stem cells.2010

    • Author(s)
      Kobayashi T, Yamaguchi T, Hamanaka S, Kato-Itoh M, Yamazaki Y, Ibata M, Sato H, Lee YS, Usui J, Knisely AS, Hirabayashi M, Nakauchi H.
    • Journal Title

      Cell

      Volume: 3 Pages: 787-99

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659058
  • [Journal Article] Downregulation of ZEB1 and overexpression of Smad7 contribute to resistance to TGF-beta1-mediated growth suppression in adult T-cell leukemia/lymphoma2010

    • Author(s)
      Nakahata S, Yamazaki S, Nakauchi H, Morishita K.
    • Journal Title

      Oncogene

      Volume: 29 Pages: 4157-69

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249059
  • [Journal Article] FET family proto-oncogene Fus contributes to self-renewal of hematopoietic stem cells2010

    • Author(s)
      Sugawara T, Oguro H, Negishi M, Morita Y, Ichikawa H, Iseki T, Yokosuka O, Nakauchi H, Iwama A
    • Journal Title

      Exp Hematol

      Volume: 38 Pages: 696-706

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249059
  • [Journal Article] Tissue type plasminogen activator regulates myeloid-cell dependent neoangiogenesis during tissue regeneration.2010

    • Author(s)
      Ohki M, Ohki Y, Ishihara M, Nishida C, Tashiro Y, AkiyamaH, Komiyama H, Lund LR, NittaA, Yamada K, Zhu Z, Ogawa H, Yagita H, Okumura K, NakauchiH, Werb Z, Heissig B, Hattori K.
    • Journal Title

      Blood

      Volume: 115 Pages: 4302-12

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249059
  • [Journal Article] Reprogramming adult hematopoietic cells.2010

    • Author(s)
      Kaneko S, Otsu M, Nakauchi H.
    • Journal Title

      Curr Opin Hematol

      Volume: 17 Pages: 271-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659058
  • [Journal Article] Koeffler HP, Gain-of-function c-CBL mutations associated with uniparental disomy of 11q in myeloid neoplasms2010

    • Author(s)
      Ogawa S, Sanada M, Shih LY, Suzuki T, Otsu M, Nakauchi H
    • Journal Title

      Cell Cycle

      Volume: 9 Pages: 1051-6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249059
  • [Journal Article] Poised lineage specification in multipotential hematopoietic stem and progenitor cells by the polycomb protein Bmil.2010

    • Author(s)
      Oguro H, Yuan J, Ichikawa H, Ikawa T, Yamazaki S, Kawamoto H, Nakauchi H, Iwama A.
    • Journal Title

      Cell Stem Cell. 6(3)

      Pages: 279-86

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249059
  • [Journal Article] Heterogeneity and hierarchy within the most primitive hematopoietic stem cell compartment.2010

    • Author(s)
      Morita Y, Ema H, Nakauchi H.
    • Journal Title

      J Exp Med

      Volume: 207 Pages: 1173-1182

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249059
  • [Journal Article] Downregulation of ZEB1 and overexpression of Smad7 contribute to resistance to TGF-β1-mediated growth suppression in adult T-cell leukemia/lymphoma2010

    • Author(s)
      Nakahata, S., Yamazaki, H., Nakauchi, H., Morishita, K
    • Journal Title

      Oncogene

      Volume: 29 Issue: 29 Pages: 4157-4159

    • DOI

      10.1038/onc.2010.172

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390098, KAKENHI-PROJECT-22659058
  • [Journal Article] Transient activation of c-MYC expression is critical for efficient platelet generation from human induced pluripotent stem cells2010

    • Author(s)
      Takayama N, Nishimura S, Nakamura S, Shimizu T, Ohnishi R, Endo H, Yamaguchi T, Otsu M, Nishimura K, Nakanishi M, Sawaguchi A, Nagai R, Takahashi K, Yamanaka S, Nakauchi H, Eto K
    • Journal Title

      J Exp Med

      Volume: 207 Pages: 2817-30

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249059
  • [Journal Article] Lnk regulates integrin alphaIIbbeta3 outside-in signaling in mouse platelets, leading to stabilization of thrombus development in vivo2010

    • Author(s)
      Takizawa H, Nishimura S, Takayama N, Oda A, Nishikii H, Morita Y, Kakinuma S, Yamazaki S, Okamura S, Tamura N, Goto S, Sawaguchi A, Manabe I, Takatsu K, Nakauchi H, Takaki S, Eto K
    • Journal Title

      J Clin Invest

      Volume: 120 Pages: 179-90

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249059
  • [Journal Article] Downregulation of ZEB1 and overexpression of Smad7 contribute to resistance to TGF-beta 1-mediated growth suppression in adult T-cell leukemia/lymphoma.2010

    • Author(s)
      Nakahata S, Yamazaki S, Nakauchi H, Morishita K.
    • Journal Title

      Oncogene

      Volume: 29 Pages: 4157-69

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659058
  • [Journal Article] Reduction of N-Glycolylneuraminic Acid in Human Induced Pluripotent Stem Cells Generated or Cultured under Feeder-and Serum-Free Defined Conditions2010

    • Author(s)
      Hayashi Y, Chan T, Warashina M, et al.(14名9番目)
    • Journal Title

      PLoS One

      Volume: 5 Issue: 11 Pages: e14099-e14099

    • DOI

      10.1371/journal.pone.0014099

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390321, KAKENHI-PROJECT-22500385, KAKENHI-PROJECT-22659058
  • [Journal Article] Transient activation of c-MYC expression is critical for efficient platelet generation from human induced pluripotent stem cells2010

    • Author(s)
      Takayama N, Nishimura S, Nakamura S, et al.(16名16番目)
    • Journal Title

      Journal of Experimental Medicine

      Volume: 207 Issue: 13 Pages: 2817-2830

    • DOI

      10.1084/jem.20100844

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390321, KAKENHI-PROJECT-22659058
  • [Journal Article] Poised lineage specification in multipotential hematopoietic stem and progenitor cells by the polycomb protein Bmil2010

    • Author(s)
      Oguro H, Yuan J, Ichikawa H, Ikawa T, Yamazaki S, Kawamoto H, Nakauchi H, Iwama A
    • Journal Title

      Cell Stem Cell

      Volume: 6 Pages: 279-86

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249059
  • [Journal Article] Reduction of N-Glycolylneuraminic Acid in Human Induced Pluripotent Stem Cells Generated or Cultured under Feeder- and Serum-Free Defined Conditions.2010

    • Author(s)
      HayashiY, Chan T, Warashina M, Fukuda M, Ariizumi T, Okabayashi K, Takayama N, Otsu M, Eto K, Furue MK, Michiue T, Ohnuma K, Nakauchi H, Asashima M.
    • Journal Title

      PLoS One

      Volume: 23

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659058
  • [Journal Article] Transcriptional profiling of hematopoieticstem cells by high-throughput sequencing2009

    • Author(s)
      Yashiro Y, Bannai H, Minowa T, Yabiku T, Miyano S, Osawa M, Iwama A, Nakauchi H
    • Journal Title

      Int J Hematol 89

      Pages: 24-33

    • Data Source
      KAKENHI-PROJECT-19209036
  • [Journal Article] The actin polymerization regulator WAVE2 is required for early bone marrow repopulation by hematopoietic stem cells.2009

    • Author(s)
      Ogaeri T, Eto K, Otsu M, Ema H, Nakauchi H.
    • Journal Title

      Stem Cells 27

      Pages: 1120-1129

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249059
  • [Journal Article] A rapid and efficient strategy to generate allele-specific anti-HLA monoclonal antibodies.2009

    • Author(s)
      Yamazaki S, Suzuki N, Saito T, Ishii Y, Takiguchi M, Nakauchi H, Watanabe N.
    • Journal Title

      J Immunol Methods. 343

      Pages: 56-60

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249059
  • [Journal Article] Cardiac mast cells cause atrial fibrillation through PDGF-A-mediated fibrosis in pressure-overloaded mouse hearts.2009

    • Author(s)
      Liao CH, Akazawa H, Tamagawa M, Ito K, Yasuda N, Kudo Y, Yamamoto R, Ozasa Y, Fujimoto M, Wang P, Nakauchi H, Nakaya H, Komuro I.
    • Journal Title

      J Clin Invest. 120

      Pages: 242-53

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249059
  • [Journal Article] Sall4 regulates cell fate decision in fetal hepatic stem/progenitor cells.12009

    • Author(s)
      Oikawa T, Kamiya A, Kakinuma S, Zeniya M, Nishinakamura R, Tajiri H, Nakauchi H.
    • Journal Title

      Gastronterology. 136

      Pages: 1000-1011

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659066
  • [Journal Article] rapid and efficient strategy to generateallele-specific anti-HLA monoclonalantibodies2009

    • Author(s)
      Yamazaki S, Suzuki N, Saito T, Ishii Y,Takiguchi M, Nakauchi H, Watanabe N. A
    • Journal Title

      J Immunol Methods 343

      Pages: 56-60

    • Data Source
      KAKENHI-PROJECT-19209036
  • [Journal Article] TGF-b induces hibernation of hematopoietic stem cells in the bone marrow niche.2009

    • Author(s)
      Yamazaki S, Iwama A, Takayanagi S, Eto K, Ema H, Nakauchi H.
    • Journal Title

      Blood 113

      Pages: 1250-1256

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209036
  • [Journal Article] TGF-b induces hibernation of hematopoietic stem cells in the bone marrow niche2009

    • Author(s)
      Yamazaki S, Iwama A, Takayanagi S, Eto K, Ema H, Nakauchi H
    • Journal Title

      Blood

      Volume: 113 Pages: 1250-1256

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249059
  • [Journal Article] Definitive proof for direct reprogramming of hematopoietic cells to pluripotency.2009

    • Author(s)
      Okabe M, Otsu M, Ahn DH, Kobayashi T, Wakiyama Y, Morita Y, Onodera M, Eto K, Ema H, Nakauchi H.
    • Journal Title

      Blood 114

      Pages: 1764-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249059
  • [Journal Article] Definitive proof for direct reprogramming of hematopoietic cells to pluripotency2009

    • Author(s)
      Okabe M, Otsu M, Ahn DH, Kobayashi T, Wakiyama Y, Morita Y, Onodera M, Eto K, Ema H, Nakauchi H
    • Journal Title

      Blood

      Volume: 114 Pages: 1764-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249059
  • [Journal Article] Insights intosignaling and function of hematopoieticstem cells at the single-cell leve2009

    • Author(s)
      Yamazaki S, Nakauchi H
    • Journal Title

      CurrOpin Hematol (in press).

    • Data Source
      KAKENHI-PROJECT-19209036
  • [Journal Article] Transcriptional profiling of hematopoietic stem cells by high-throughput sequencing.2009

    • Author(s)
      Yashiro Y, Bannai H, Minowa T, Yabiku T, Miyano S, Osawa M, Iwama A, Nakauchi H.
    • Journal Title

      Int J Hematol 89

      Pages: 24-33

    • NAID

      10025159521

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209036
  • [Journal Article] Tumor suppression by phospholipase C-beta3 via SHP-1-mediated dephosphorylation of Stat5.2009

    • Author(s)
      Xiao W, Hong H, Kawakami Y, Kato Y, Wu D, Yasudo H, Kimura A, Kubagawa H, Bertoli LF, Davis RS, Chau LA, Madrenas J, Hsia CC, Xenocostas A, Kipps TJ, Hennighausen L, Iwama A, Nakauchi H, Kawakami T.
    • Journal Title

      Cancer Cell. 16

      Pages: 161-71

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249059
  • [Journal Article] Hepatic stem/progenitor cells and stem-celltransplantation for the treatment of liverdisease2009

    • Author(s)
      Kakinuma S, Nakauchi H, Watanabe M
    • Journal Title

      J Gastroenterol 44

      Pages: 167-72

    • NAID

      10025173601

    • Data Source
      KAKENHI-PROJECT-19209036
  • [Journal Article] Stepwise development of hematopoietic stem cells from embryonic stem cells.2009

    • Author(s)
      Matsumoto K, Isagawa T, Nishimura T, Ogaeri T, Eto K, Miyazaki S, Miyazaki JI, Aburatani H, Nakauchi H, Ema H.
    • Journal Title

      PLoS ONE 4(3)

    • NAID

      120004898447

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209036
  • [Journal Article] Sall4 regulates cell fate decision in fetalhepatic stem/progenitor cells2009

    • Author(s)
      Oikawa T, Kamiya A, Kakinuma S, ZeniyaM, Nishinakamura R, Tajiri H, Nakauchi H
    • Journal Title

      Gastroenterology 136

      Pages: 1000-11

    • Data Source
      KAKENHI-PROJECT-19209036
  • [Journal Article] The actin polymerization regulator WAVE2 is required for early bone marrow repopulation by hematopoietic stem cells2009

    • Author(s)
      Ogaeri T, Eto K, Otsu M, Ema H, Nakauchi H
    • Journal Title

      Stem Cells

      Volume: 27 Pages: 1120-1129

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249059
  • [Journal Article] TGF-b induces hibernation of hematopoietic stem cells in the bone marrow niche.Blood.2009

    • Author(s)
      Yamazaki S, Iwama A, Takayanagi S, Eto K, Ema H, Nakauchi H.
    • Journal Title

      Blood 113

      Pages: 1250-56

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249059
  • [Journal Article] Gain-of-function of mutated C-CBL tumour suppressor in myeloid neoplasms.2009

    • Author(s)
      Sanada M, Suzuki T, Shih LY, Otsu M, Kato M, Yamazaki S, Tamura A, Honda H, Sakata-Yanagimoto M, Kumano K, Oda H, Yamagata T, Takita J, Gotoh N, Nakazaki K, Kawamata N, Onodera M, Nobuyoshi M, Hayashi Y, Harada H, Kurokawa M, Chiba S, Mori H, Ozawa K, Omine M, Hirai H, Nakauchi H, Koeffler HP, Ogawa S.
    • Journal Title

      Nature 460

      Pages: 904-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249059
  • [Journal Article] Tumor suppression by phospholipase C-beta3 via SHP-1-mediated dephosphorylation of Stat52009

    • Author(s)
      Xiao W, Hong H, Kawakami Y, Kato Y, Wu D, Yasudo H, Kimura A, Kubagawa H, Bertoli LF, Davis RS, Chau LA, Madrenas J, Hsia CC, Xenocostas A, Kipps TJ, Hennighausen L, Iwama A, Nakauchi H, Kawakami T
    • Journal Title

      Cancer Cell

      Volume: 16 Pages: 161-71

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249059
  • [Journal Article] Analyses of cell surface molecules onhepatic stem/progenitor cells in mouse fetalliver2009

    • Author(s)
      Kakinuma S, Ohta H, Kamiya A, YamazakiY, Oikawa T, Okada K, Nakauchi H.
    • Journal Title

      J Hepatol. (in press)

    • Data Source
      KAKENHI-PROJECT-19209036
  • [Journal Article] Comparison of mesenchymal stem cells derived form arterial, venous, and Wharton's jelly explants of human umbilical cord2009

    • Author(s)
      Ishige I, Nagamura-Inoue T, Honda MJ, Harnprasopwat R, Kido M, Sugimoto M, Nakauchi H, Tojo A.
    • Journal Title

      Int J Hematol. 90

      Pages: 261-69

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249059
  • [Journal Article] cell growth control using hapten-specificantibody/interleukin-2 receptor chimera2009

    • Author(s)
      Onodera M, Nakauchi H, Nagamune T. T
    • Journal Title

      Cytokine(in press)

    • Data Source
      KAKENHI-PROJECT-19209036
  • [Journal Article] A rapid and efficient strategy to generate allele-specific anti-HLA monoclonal antibodies.2009

    • Author(s)
      Yamazaki S, Suzuki N, Saito T, Ishii Y, Takiguchi M, Nakauchi H, Watanabe N.
    • Journal Title

      J Immunol Methods 343

      Pages: 56-60

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209036
  • [Journal Article] A rapid and efficient strategy to generate allele-specific anti-HLA monoclonal antibodies.2009

    • Author(s)
      Yamazaki S, Suzuki N, Saito T, Ishii Y, Takiguchi M, Nakauchi H, Watanabe N.
    • Journal Title

      J Immunol Methods. 343

      Pages: 56-60

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659066
  • [Journal Article] T cell growth control using hapten-specific antibody/interleukin-2 receptor chimera.2009

    • Author(s)
      Sogo T, Kawahara M, Ueda H, Otsu M, Onodera M, Nakauchi H, Nagamune T.
    • Journal Title

      Cytokine 46

      Pages: 127-36

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249059
  • [Journal Article] Sall4 regulates cell fate decision in fetal hepatic stem/progenitor cells.2009

    • Author(s)
      Oikawa T, Kamiya A, Kakinuma S, Zeniya M, Nishinakamura R, Tajiri H, Nakauchi H.
    • Journal Title

      Gastroenterology. 136

      Pages: 1000-11

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209036
  • [Journal Article] Stepwise development of hematopoieticstem cells from embryonic stem cells2009

    • Author(s)
      Matsumoto K, Isagawa T, Nishimura T, Ogaeri T, Eto K, Miyazaki S, Miyazaki J, Aburatani H, Nakauchi H, Ema H
    • Journal Title

      PLoS ONE 4820

    • Data Source
      KAKENHI-PROJECT-19209036
  • [Journal Article] Insights into signaling and function of hematopoietic stem cells at the single-cell level.2009

    • Author(s)
      Yamazaki S, Nakauchi H.
    • Journal Title

      Curr Opin Hematol. 16

      Pages: 255-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249059
  • [Journal Article] TGF-b induceshibernation of hematopoietic stem cells inthe bone marrow niche2009

    • Author(s)
      Yamazaki S, Iwama A, Takayanagi S, Eto K, Ema H, Nakauchi H
    • Journal Title

      Blood 113

      Pages: 1250-1256

    • Data Source
      KAKENHI-PROJECT-19209036
  • [Journal Article] Ex vivo expansion of human hematopoietic stem cells by a small-molecule agonist of c-MPL.2009

    • Author(s)
      Nishino T, Miyaji K, Ishiwata N, Arai K, Yui M, Asai Y, Nakauchi H, Iwama A.
    • Journal Title

      Exp Hematol. 37

      Pages: 1364-77

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249059
  • [Journal Article] Gain-of-function of mutated C-CBL tumour suppressor in myeloid neoplasms2009

    • Author(s)
      Sanada M, Suzuki T, Shih LY, Otsu M, Kato M, Yamazaki S, Tamura A, Honda H, Sakata-Yanagimoto M, Kumano K, Oda H, Yamagata T, Takita J, Gotoh N, Nakazaki K, Kawamata N, Onodera M, Nobuyoshi M, Hayashi Y, Harada H, Kurokawa M, Chiba S, Mori H, Ozawa K, Omine M, Hirai H, Nakauchi H, Koeffler HP, Ogawa S
    • Journal Title

      Nature

      Volume: 460 Pages: 904-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249059
  • [Journal Article] Insights into signaling and function of hematopoietic stem cells at the single-cell level2009

    • Author(s)
      Yamazaki S, Nakauchi H
    • Journal Title

      Curr Opin Hemato

      Volume: 16 Pages: 255-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249059
  • [Journal Article] The actin polymerization regulatorWAVE2 is required for early bone marrowrepopulation by hematopoietic stem cells2009

    • Author(s)
      Ogaeri T, Eto K, Otsu M, Ema H, NakauchiH
    • Journal Title

      Stem Cells 27

      Pages: 1120-1129

    • Data Source
      KAKENHI-PROJECT-19209036
  • [Journal Article] Stepwise development of hematopoietic stem cells from embryonic stem cells2009

    • Author(s)
      Matsumoto K, Isagawa T, Nishimura T, Ogaeri T, Eto K, Miyazaki S, Miyazaki J, Aburatani H, Nakauchi H, Ema H
    • Journal Title

      PLoS ONE

      Volume: 4

    • NAID

      120004898447

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249059
  • [Journal Article] Stepwise development of hematopoietic stem cells from embryonic stem cells.2009

    • Author(s)
      Matsumoto K, Isagawa T, Nishimura T, Ogaeri T, Eto K, Miyazaki S, Miyazaki J, Aburatani H, Nakauchi H, Ema H
    • Journal Title

      PLoS ONE. 4

    • NAID

      120004898447

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249059
  • [Journal Article] Flow cytometric isolation and clonalidentification of self-renewing bipotenthepatic progenitor cells in adult mouse liver2008

    • Author(s)
      Suzuki A, Sekiya S, Onishi M, Oshima N, Kiyonari H, Nakauchi H, Taniguchi H
    • Journal Title

      Hepatology 48

      Pages: 1964-78

    • Data Source
      KAKENHI-PROJECT-19209036
  • [Journal Article] guidelines underscore major principles forresponsible translational stem cell research.2008

    • Author(s)
      Hyun I, Lindvall O, Ahrlund-Richter L Cattaneo E, Cavazzana-Calvo M, Cossu G, De Luca M, Fox IJ, Gerstle C, GoldsteinRA, Hermeren G, High KA, Kim HO, LeeHP, Levy-Lahad E, Li L, Lo B, MarshakDR, McNab A, Munsie M, Nakauchi H, Rao M, Rooke HM, Valles CS, Srivastava A, Sugarman J, Taylor PL, Veiga A, Wong AL, Zoloth L, Daley GQ. New ISSCR
    • Journal Title

      Cell Stem Cell. 3

      Pages: 607-9

    • Data Source
      KAKENHI-PROJECT-19209036
  • [Journal Article] Growth and maturation of megakaryocytes is regulatedby Lnk/Sh2b3 adaptor protein throughcrosstalk between cytokine- andintegrin-mediated signals2008

    • Author(s)
      Takizawa H, Eto K, Yoshikawa A, NakauchiH, Takatsu K, Takaki S.
    • Journal Title

      Exp Hematol 36

      Pages: 897-906

    • Data Source
      KAKENHI-PROJECT-19209036
  • [Journal Article] Thepolycomb gene product BMI1 contributesto the maintenance of tumor-initiating sidepopulation cells in hepatocellular carcinoma2008

    • Author(s)
      Chiba T, Miyagi S, Saraya A, Aoki R, SekiA, Morita Y, Yonemitsu Y, Yokosuka O, Taniguchi H, Nakauchi H, Iwama A.
    • Journal Title

      Cancer Res 68

      Pages: 7742-9

    • Data Source
      KAKENHI-PROJECT-19209036
  • [Journal Article] Recipient-derived cells after cord blood transplantation: dynamics by multicolor FACS, reflecting graft failure and relapse.2008

    • Author(s)
      Watanabe N, Takahashi S, Ishige M, Ishii Y, Ooji, Tomonari A, Tsukada N, Konuma T, Kato S, Sato A, Tojo A, Nakauchi H.
    • Journal Title

      Biol Blood Marrow Transplant. 14

      Pages: 693-701

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659066
  • [Journal Article] Generation of functional erythrocytes from human embryonic stem cell-derived definitive hematopolesis.2008

    • Author(s)
      Ma F, Ebihara Y, Umeda K, Sakai H, Hanada S, Zhang H, Zaike Y, Tsuchida E, Nakahata T, Nakauchi H, Tsuji K.
    • Journal Title

      Proc Natl Acad Sci U S A 105

      Pages: 13087-92

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209036
  • [Journal Article] Prospero-related homeobox 1 and liver receptor homolog 1 coordinately regulate long-term proliferation of murine fetal hepatoblasts.2008

    • Author(s)
      Kamiya A, Kakinuma S, Onodera M, Miyajima A, Nakauchi H.
    • Journal Title

      Hepatology 48

      Pages: 252-64

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209036
  • [Journal Article] Prospero-related homeobox 1 and liverreceptor homolog 1 coordinately regulatelong-term proliferation of murine fetalhepatoblasts2008

    • Author(s)
      Kamiya A, Kakinuma S, Onodera M, Miyajima A, Nakauchi H
    • Journal Title

      Hepatology 48

      Pages: 252-64

    • Data Source
      KAKENHI-PROJECT-19209036
  • [Journal Article] Metalloproteinaseregulation improves in vitro generation ofefficacious platelets from mouse embryonicstem cells2008

    • Author(s)
      Nishikii H, Eto K, Tamura N, Hattori1 K,Heissig B, Kanaji T, Sawaguchi A, Goto S,Ware J, Nakauchi H
    • Journal Title

      J Exp Med 205

      Pages: 1917-27

    • Data Source
      KAKENHI-PROJECT-19209036
  • [Journal Article] Interleukin-27 directlyinduces differentiation in hematopoieticstem cells2008

    • Author(s)
      Seita J, Asakawa M, Ooehara J, TakayanagiSI, Morita Y, Watanabe N, Fujita K, KudoM, Mizuguchi J, Ema H, Nakauchi H, Yoshimoto Y
    • Journal Title

      Blood 111

      Pages: 1903-12

    • Data Source
      KAKENHI-PROJECT-19209036
  • [Journal Article] Recipient-derived cells after cord blood transplantation: dynamics elucidated by multicolor FACS, reflecting graft failure and relapse.2008

    • Author(s)
      Watanabe N, Takahashi S, Ishige M, Ishii Y, Ooi J, Tomonari A, Tsukada N, Konuma T, Kato S, Sato A, Tojo A, Nakauchi H.
    • Journal Title

      Biol Blood Marrow Transplant 14

      Pages: 693-701

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209036
  • [Journal Article] Recipient-derived cells after cord bloodtransplantation : dynamics elucidated bymulticolor FACS, reflecting graft failureand relapse2008

    • Author(s)
      Watanabe N, Takahashi S, Ishige M, Ishii Y, Ooi J, Tomonari A, Tsukada N, Konuma T, Kato S, Sato A, Tojo A, Nakauchi H
    • Journal Title

      Biol Blood Marrow Transplant 14

      Pages: 693-701

    • Data Source
      KAKENHI-PROJECT-19209036
  • [Journal Article] Flow cytometric isolation and clonal indentification of self-renewing bipotent hepatic progenitor cells in adult mouse liver.2008

    • Author(s)
      Suzuki, A, Sekiya S, Onishi M, Oshima N, Kiyonari H, Nakauchi H, Taniguchi H.
    • Journal Title

      Hepatlogy 48

      Pages: 1964-1978

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659066
  • [Journal Article] Generation of functional platelets from human embryonic stem cells in vitro via ES-sacs, VEGF-promoted structures that concentrate hematopoietic progenitors.2008

    • Author(s)
      Takayama N, Nishikii H, Usui J, Tsukui H, Sawaguchi A, Hiroyama T, Eto K, Nakauchi H.
    • Journal Title

      Blood 1

      Pages: 5298-306

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209036
  • [Journal Article] Generation of functional erythrocytes fromhuman embryonic stem cell-deriveddefinitive hematopoiesis2008

    • Author(s)
      Ma F, Ebihara Y, Umeda K, Sakai H, Hanada S, Zhang H, Zaike Y, Tsuchida E, Nakahata T, Nakauchi H, Tsuji K
    • Journal Title

      Proc Natl AcadSci U S A 105

      Pages: 13087-92

    • Data Source
      KAKENHI-PROJECT-19209036
  • [Journal Article] Interleukin-27 directly induces differentiation in hematopoietic stem cells.2008

    • Author(s)
      Seita J, Asakawa M, Ooehara J, Takayanagi SI, Morita Y, Watanabe N, Fujita K, Kudo M, Mizuguchi J, Ema H, Nakauchi H, Yoshimoto Y.
    • Journal Title

      Blood 111

      Pages: 1903-12

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209036
  • [Journal Article] An immunotherapy approachwith dendritic cells genetically modified toexpress the tumor-associated antigen2008

    • Author(s)
      Nabekura T, Nagasawa T, Nakauchi H, Onodera M
    • Journal Title

      HER2.Cancer Immunol Immunother 57

      Pages: 611-22

    • Data Source
      KAKENHI-PROJECT-19209036
  • [Journal Article] The polycomb gene product BMI1 contributes to the maintenance of tumor-initiating side population cells in hepatocellular carcinoma.2008

    • Author(s)
      Chiba T, Miyagi S, Saraya A, Aoki R, Seki A, Morita Y, Yonemitsu Y, Yokosuka 0, Taniguchi H, Nakauchi H, Iwama A.
    • Journal Title

      Cancer Re 68

      Pages: 7742-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209036
  • [Journal Article] Generation of functional platelets fromhuman embryonic stem cells in vitro viaES-sacs, VEGF-promoted structures thatconcentrate hematopoietic progenitors2008

    • Author(s)
      Takayama N, Nishikii H, Usui J, Tsukui H, Sawaguchi A, Hiroyama T, Eto K, Nakauchi H
    • Journal Title

      Blood 1

      Pages: 5298-306

    • Data Source
      KAKENHI-PROJECT-19209036
  • [Journal Article] Growth and maturation of megakaryocytes is regulated by Lnk/Sh2b3 adaptor protein through crosstalk between cytokine-and integrin-mediated signals.2008

    • Author(s)
      Takizawa H, Eto K, Yoshikawa A, Nakauchi H, Takatsu K, Takaki S.
    • Journal Title

      Exp Hematol 36

      Pages: 897-906

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209036
  • [Journal Article] The polycomb gene product BMI1 contributes to the maintenance of tumor-initiating side population cells in hepatocellular carcinoma.2008

    • Author(s)
      Chiba T, Miyagi S, Saraya A, Aoki R, Seki A, Morita Y, Yonemitsu Y, Yokosuka O, Taniguchi H. Nakauchi H, Iwama A.
    • Journal Title

      Cancer Res 68

      Pages: 13087-13092

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659066
  • [Journal Article] Metalloprotrinase regulation improves in vitro generation of efficacious platelets from mouse embryonic stem cells.2008

    • Author(s)
      Nishikii H, Eto K, Tamura N, Hattoril K, Heissig B, Kanaji T, Sawaguchi A, Goto S, Ware J, Nakauchi H.
    • Journal Title

      J Exp Med 205

      Pages: 1917-27

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209036
  • [Journal Article] Stable Transgene Expression in MiceGenerated from Retrovirally TransducedEmbryonic Stem2007

    • Author(s)
      Hamanaka S, Nabekura T, Otsu M, YoshidaH, Nagata M, Usui J, Takahashi S,Nagasawa T, Nakauchi H, Onodera M
    • Journal Title

      Cells. Mol Ther 15

      Pages: 560-5

    • Data Source
      KAKENHI-PROJECT-19209036
  • [Journal Article] The Plasminogen Fibrinolytic Pathway Is Required for Hematopoietic Regeneration2007

    • Author(s)
      Heissig B, Lund LR, Akiyama H, Ohki M, Morita Y, Romer J, Nakauchi H, Okumura K, Ogawa H, Werb Z, Dano K, Hattori K.
    • Journal Title

      Cell Stem Cell 1

      Pages: 658-70

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209036
  • [Journal Article] Unique composition of polycomb repressive complex 1 in hematopoietic stem cells2007

    • Author(s)
      26. Kato Y, Koseki H, Vidal M, Nakauchi H, Iwama A.
    • Journal Title

      Int J Hematol 85

      Pages: 179-81

    • NAID

      10018553322

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209036
  • [Journal Article] Foxo3a is essential formaintenance of the hematopoietic stem cellpool2007

    • Author(s)
      Miyamoto K, Araki KY, Naka K, Arai F, Takubo K, Yamazaki S, Matsuoka S,Miyamoto T, Ito K, Ohmura M, Chen C, Hosokawa K, Nakauchi H, Nakayama K, Nakayama KI, Harada M, Motoyama N, Suda T, Hirao A
    • Journal Title

      Cell Stem Cell 1

      Pages: 101-12

    • Data Source
      KAKENHI-PROJECT-19209036
  • [Journal Article] De novo DNAmethyltransferase is essential forself-renewal, but not for differentiation inhematopoietic stem cells2007

    • Author(s)
      Tadokoro Y, Ema H, Okano M, Li E, Nakauchi H
    • Journal Title

      J Exp Med 204

      Pages: 715-22

    • Data Source
      KAKENHI-PROJECT-19209036
  • [Journal Article] De novo DNA methyltransferase is essential for self-renewal, but not for differentiation, in hematopoietic stem cells2007

    • Author(s)
      Tadokoro Y, Ema H, Okano M, Li E, Nakauchi H.
    • Journal Title

      J Exp Med 204

      Pages: 715-22

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209036
  • [Journal Article] Cytokine signaling, lipid raft clustering, and HSC hibernation2007

    • Author(s)
      Yamazaki S, Iwama A, Morita Y, Eto K, Ema H, Nakauchi H. Cytokine signaling, lipid raft clustering, HSC hibernation
    • Journal Title

      Ann N Y Acad Sci 1106

      Pages: 54-63

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209036
  • [Journal Article] Lnk negatively regulates self-renewal of hematopoietic stem cells by modifying thrombopoietin-mediated signal transduction2007

    • Author(s)
      Seita, J., Ema, H., Ooehara, J., Yamazaki, S., Tadokoro, Y., Yamazaki, A., Eto, K., Takaki, S., Takatsu, K., Nakauchi H.
    • Journal Title

      Proc Natl Acad Sci USA 104

      Pages: 2349-54

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209036
  • [Journal Article] Foxo3a is essential for maintenance of the hematopoietic stem cell pool2007

    • Author(s)
      Miyamoto K, Araki KY, Naka K, Arai F, Takubo K, Yamazaki S, Matsuoka S, Miyamoto T, Ito K, Ohmura M, Chen C, Hosokawa K, Nakauchi H, Nakayama K
    • Journal Title

      Cell Stem Cell 1

      Pages: 101-12

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209036
  • [Journal Article] Stable Transgene Expression in Mice Generated from Retrovirally Transduced Embryonic Stem Cells2007

    • Author(s)
      Hamanaka S, Nabekura T, Otsu M, Yoshida H, Nagata M, Usui J, Takahashi S, Nagasawa T, Nakauchi H, Onodera M.
    • Journal Title

      Mol Ther. 15

      Pages: 560-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209036
  • [Journal Article] The WAVE2/Abi1 complex differentially regulates megakaryocyte development and spreading : implications for platelet biogenesis and spreading machinery2007

    • Author(s)
      Eto K, Nishikii H, Ogaeri T, Suetsugu S, Kamiya A, Kobayashi T, Yamazaki D, Oda A, Takenawa T, Nakauchi H.
    • Journal Title

      Blood 110

      Pages: 3637-47

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209036
  • [Journal Article] Iawama A. Bmi1 cooperates withDnmt1-assciated protein 1 in gene silencing2007

    • Author(s)
      Negishi M, Saraya A, Miyagi S, Nagao K,Inagaki Y, Nishikawa M, Tajima S, KosekiH, Tsuda H, Takasaki Y, Nakauchi H
    • Journal Title

      Biochem Biophys Res Commun 353

      Pages: 992-8

    • Data Source
      KAKENHI-PROJECT-19209036
  • [Journal Article] Cytokine signaling, lipid raft clustering, and HSC hibernation2007

    • Author(s)
      Yamazaki S, Iwama A, Morita Y, Eto K,Ema H, Nakauchi H
    • Journal Title

      Ann N Y Acad Sci 1106

      Pages: 54-63

    • Data Source
      KAKENHI-PROJECT-19209036
  • [Journal Article] Enhancedself-renewal capability in hepaticstem/progenitor cells drives cancerinitiation2007

    • Author(s)
      Chiba T, Zheng YW, Kita K, Yokosuka O,Saisho H, Onodera M, Miyoshi H, NakanoM, Zen Y, Nakanuma Y, Nakauchi H, Iwama A, Taniguchi H.
    • Journal Title

      Gastroenterology 137

      Pages: 937-50

    • Data Source
      KAKENHI-PROJECT-19209036
  • [Journal Article] The Plasminogen Fibrinolytic Pathway IsRequired for Hematopoietic Regeneration2007

    • Author(s)
      Heissig B, Lund LR, Akiyama H, Ohki M, Morita Y, Romer J, Nakauchi H, OkumuraK, Ogawa H, Werb Z, Dano K, Hattori K
    • Journal Title

      Cell Stem Cell 1

      Pages: 658-70

    • Data Source
      KAKENHI-PROJECT-19209036
  • [Journal Article] Enhanced self-renewal capability in hepatic stem/progenitor cells drives cancer initiation2007

    • Author(s)
      Chiba T, Zheng YW, Kita K, Yokosuka O, Saisho H, Onodera M, Miyoshi H, Nakano M, Zen Y, Nakanuma Y, Nakauchi H, Iwama A, Taniguchi H.
    • Journal Title

      Gastroenterology 133

      Pages: 937-50

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209036
  • [Journal Article] Lnknegatively regulates self-renewal ofhematopoietic stem cells by modifyingthrombopoietin-mediated signaltransduction2007

    • Author(s)
      Seita, J., Ema, H., Ooehara, J., Yamazaki, S.,Tadokoro, Y., Yamazaki, A., Eto, K., Takaki,S., Takatsu, K., and Nakauchi H
    • Journal Title

      Proc Natl Acad Sci USA 104

      Pages: 2349-54

    • Data Source
      KAKENHI-PROJECT-19209036
  • [Journal Article] Unique composition ofpolycomb repressive complex 1 inhematopoietic stem cells2007

    • Author(s)
      Kato Y, Koseki H, Vidal M, Nakauchi H, Iwama A
    • Journal Title

      Int J Hematol 85

      Pages: 179-81

    • Data Source
      KAKENHI-PROJECT-19209036
  • [Journal Article] Bmi1 cooperates with Dnmt1-assciated protein 1 in gene silencing2007

    • Author(s)
      Negishi M, Saraya A, Miyagi S, Nagao K, Inagaki Y, Nishikawa M, Tajima S, Koseki H, Tsuda H, Takasaki Y, Nakauchi H, Iawama A.
    • Journal Title

      Biochem Biophys Res Commun 353

      Pages: 992-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209036
  • [Journal Article] De novo DNAmethyltransferase is essential forself-renewal, but not for differentiation2007

    • Author(s)
      Eto K, Nishikii H, Ogaeri T, Suetsugu S,Kamiya A, Kobayashi T, Yamazaki D, OdaA, Takenawa T, Nakauchi H
    • Journal Title

      Blood 110

      Pages: 3637-47

    • Data Source
      KAKENHI-PROJECT-19209036
  • [Journal Article] Polycomb gene product Bmi-1 regulates stem cell self-renewal.2005

    • Author(s)
      Nakauchi H, et al.
    • Journal Title

      Ernst Schering Res Found Workshop 54

      Pages: 85-100

    • Data Source
      KAKENHI-PROJECT-17209036
  • [Journal Article] Polycomb gene product Bmi-1 regulates stem cell self-renewal.2005

    • Author(s)
      Nakauchi H, et al.
    • Journal Title

      Ernst Schering Res Found Workshop 54

      Pages: 85-100

    • Data Source
      KAKENHI-PROJECT-14081202
  • [Journal Article] Liver repopulation by c-Met-positive stem/progenitor cells isolated from developing rat liver.2004

    • Author(s)
      Suzuki A, Zhen Y.W, Fukao K, Nakauchi H, Taniguchi H
    • Journal Title

      Hepatogastroenterology 51

      Pages: 429-433

    • Data Source
      KAKENHI-PROJECT-14207046
  • [Journal Article] Prospective Isolation of Multipotent Pancreatic Progenitors Using Flow-Cytometric Cell Sorting2004

    • Author(s)
      Suzuki A, Nakauchi H, Taniguchi H
    • Journal Title

      Diabetes 53(8)

      Pages: 2143-2152

    • Data Source
      KAKENHI-PROJECT-14207046
  • [Journal Article] The actin polymerization regulator WAVE2 is required for early bone marrow repopulation by hematopoietic stem cells.

    • Author(s)
      Ogaeri T, Eto K, Otsu M, Ema H, Nakauchi H.
    • Journal Title

      Stem Cells. in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209036
  • [Journal Article] Definitive proof fordirect reprogramming of hematopoieticcells to pluripotency

    • Author(s)
      Okabe M, Otsu M, Ahn DH, Kobayashi T, Wakiyama Y, Morita Y, Onodera M, Eto K, Ema H, Nakauchi H
    • Journal Title

      Blood. (in press)

    • Data Source
      KAKENHI-PROJECT-19209036
  • [Journal Article] T cell growth control using hapten-specific antibody/interleukin-2 receptor chimera.

    • Author(s)
      Sogo T, Kawahara M, Ueda H, Otsu M, Onodera M, Nakauchi H, Nagamune T.
    • Journal Title

      Cytokine. in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209036
  • [Patent] 成人T細胞白血病リンパ腫を処置することに用いるための組成物およびその製造方法2019

    • Inventor(s)
      中内啓光、石垣知寛、山崎聡、田矢祐規
    • Industrial Property Rights Holder
      国立大学法人東京大学
    • Industrial Property Rights Type
      特許
    • Filing Date
      2019
    • Overseas
    • Data Source
      KAKENHI-PROJECT-16H02661
  • [Patent] 成人T細胞白血病リンパ腫を処置することに用いるための組成物およびその製造方法2019

    • Inventor(s)
      中内啓光、石垣知寛、山崎聡、田矢祐規
    • Industrial Property Rights Holder
      国立大学法人東京大学
    • Industrial Property Rights Type
      特許
    • Filing Date
      2019
    • Overseas
    • Data Source
      KAKENHI-PROJECT-16H02661
  • [Patent] 成人T細胞白血病リンパ腫を処置することに用いるための組成物およびその製造方法2019

    • Inventor(s)
      中内啓光、石垣知寛、山崎聡、田矢祐規
    • Industrial Property Rights Holder
      国立大学法人東京大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2018-531993
    • Filing Date
      2019
    • Data Source
      KAKENHI-PROJECT-16H02661
  • [Patent] 造血幹細胞を減少させる組成物およびその製造方法2018

    • Inventor(s)
      中内啓光、山崎聡、田矢裕規
    • Industrial Property Rights Holder
      国立大学法人東京大学
    • Industrial Property Rights Type
      特許
    • Filing Date
      2018
    • Acquisition Date
      2018
    • Data Source
      KAKENHI-PROJECT-16H02661
  • [Patent] 成人T細胞白血病リンパ腫を処置することに用いるための組成物およびその製造方法2017

    • Inventor(s)
      中内啓光、山崎聡、石垣知寛、田矢祐規
    • Industrial Property Rights Holder
      中内啓光、山崎聡、石垣知寛、田矢祐規
    • Industrial Property Rights Type
      特許
    • Filing Date
      2017
    • Overseas
    • Data Source
      KAKENHI-PROJECT-16H02661
  • [Patent] 成人T細胞白血病リンパ腫を処置することに用いるための組成物およびその製造方法2016

    • Inventor(s)
      中内啓光、石垣知寛、山崎聡、田矢祐規
    • Industrial Property Rights Holder
      国立大学法人 東京大学
    • Industrial Property Rights Type
      特許
    • Filing Date
      2016-08-05
    • Data Source
      KAKENHI-PROJECT-16H02661
  • [Patent] 造血幹細胞を減少させる組成物およびその製造法2014

    • Inventor(s)
      中内 啓光、山崎 聡、田矢 祐規
    • Industrial Property Rights Holder
      国立大学法人 東京大学
    • Industrial Property Rights Type
      特許
    • Filing Date
      2014-11-25
    • Data Source
      KAKENHI-PROJECT-24249056
  • [Patent] 抗原特異的T細胞の製造方法2012

    • Inventor(s)
      中内啓光、金子新、西村聡修
    • Industrial Property Rights Holder
      東京大学
    • Industrial Property Number
      2012-116639
    • Filing Date
      2012-05-22
    • Overseas
    • Data Source
      KAKENHI-PROJECT-22659058
  • [Patent] 多能性幹細胞からの血液細胞分化に関する培養方法2011

    • Inventor(s)
      佐野進弥、江藤浩之、高山直也、中内啓光
    • Industrial Property Rights Holder
      東京大学、テルモ株式会社
    • Filing Date
      2011-09-09
    • Overseas
    • Data Source
      KAKENHI-PROJECT-21249059
  • [Patent] 多能性幹細胞からの血液細胞分化に関する培養方法2011

    • Inventor(s)
      佐野進弥、江藤浩之、高山直也、中内啓光
    • Industrial Property Rights Holder
      東京大学テルモ株式会社
    • Filing Date
      2011-09-09
    • Overseas
    • Data Source
      KAKENHI-PLANNED-23106004
  • [Patent] 誘導型多能性幹細胞の製造方法2011

    • Inventor(s)
      中内啓光, 大津真, 高山直也, 安東赫
    • Industrial Property Rights Holder
      東京大学
    • Filing Date
      2011-06-15
    • Overseas
    • Data Source
      KAKENHI-PROJECT-22659058
  • [Patent] 誘導型多能性幹細胞の製造方法2011

    • Inventor(s)
      中内啓光, 大津真, 高山直也, 安東赫
    • Industrial Property Rights Holder
      東京大学
    • Filing Date
      2011-06-15
    • Overseas
    • Data Source
      KAKENHI-PROJECT-21249059
  • [Patent] Method for Immunological Reconstitution using Pluripotent Stem Cells2011

    • Inventor(s)
      中内啓光、金子新、西村聡修
    • Industrial Property Rights Holder
      東京大学
    • Filing Date
      2011-02-03
    • Overseas
    • Data Source
      KAKENHI-PROJECT-22659058
  • [Patent] 誘導型多能性幹細胞の製造方法2011

    • Inventor(s)
      中内啓光,大津真,高山直也,安東赫
    • Industrial Property Rights Holder
      東京大学
    • Filing Date
      2011-06-15
    • Overseas
    • Data Source
      KAKENHI-PROJECT-22659058
  • [Patent] 多能性幹細胞からの血液細胞分化に関する培養方法2011

    • Inventor(s)
      佐野進弥、江藤浩之、高山直也、中内啓光
    • Industrial Property Rights Holder
      東京大学テルモ株式会社
    • Filing Date
      2011-09-09
    • Overseas
    • Data Source
      KAKENHI-PROJECT-22659058
  • [Patent] 誘導型多能性幹細胞の製造方法2011

    • Inventor(s)
      中内啓光,大津真,高山直也,安東赫
    • Industrial Property Rights Holder
      東京大学
    • Filing Date
      2011-06-15
    • Overseas
    • Data Source
      KAKENHI-PROJECT-21249059
  • [Patent] 多能性幹細胞からの血液細胞分化に関する培養方法2011

    • Inventor(s)
      佐野進弥、江藤浩之、高山直也、中内啓光
    • Industrial Property Rights Holder
      東京大学テルモ株式会社
    • Filing Date
      2011-09-09
    • Overseas
    • Data Source
      KAKENHI-PROJECT-21249059
  • [Patent] 多能性幹細胞からの血液細胞分化に関する培養方法2011

    • Inventor(s)
      佐野進弥、江藤浩之、高山直也、中内啓光
    • Industrial Property Rights Holder
      東京大学、テルモ株式会社
    • Filing Date
      2011-09-09
    • Overseas
    • Data Source
      KAKENHI-PROJECT-22659058
  • [Patent] iPS 細胞からの血小板の調製方法2009

    • Inventor(s)
      中内啓光、江藤浩之、錦井秀和、高山直也、山中伸弥、高橋和利
    • Industrial Property Rights Holder
      国立大学法人 東京大学
    • Filing Date
      2009-04-01
    • Data Source
      KAKENHI-PROJECT-19209036
  • [Patent] ウイルス産生細胞2009

    • Inventor(s)
      中内啓光、江藤浩之、大津真、高山直也
    • Industrial Property Rights Holder
      国立大学法人 東京大学
    • Filing Date
      2009-05-15
    • Data Source
      KAKENHI-PROJECT-19209036
  • [Patent] GPIbα+GPV+GPVI+血小板のインビトロ調製法2009

    • Inventor(s)
      中内啓光、江藤浩之、錦井秀和、高山直也
    • Industrial Property Rights Holder
      国立大学法人 東京大学
    • Filing Date
      2009-03-27
    • Data Source
      KAKENHI-PROJECT-19209036
  • [Patent] 遺伝子改変による致死性表現型を持つ動物の繁殖用ファウンダー動物作製法2008

    • Inventor(s)
      中内啓光, 小林俊寛
    • Industrial Property Rights Holder
      国立大学法人東京大学
    • Industrial Property Number
      2008-042243
    • Filing Date
      2008-02-22
    • Data Source
      KAKENHI-PROJECT-19209036
  • [Patent] iPS 細胞からの血小板の調製方法2008

    • Inventor(s)
      中内啓光、江藤浩之、錦井秀和、高山直也、山中伸弥(京大)、高橋和利(京大)
    • Industrial Property Rights Holder
      国立大学法人東京大学、国立大学法人京都大学
    • Industrial Property Number
      2008-094584
    • Filing Date
      2008-04-01
    • Data Source
      KAKENHI-PROJECT-19209036
  • [Patent] GPIbα+血小板のインビトロ調製法2008

    • Inventor(s)
      中内啓光、江藤浩之、錦井秀和、高山直也
    • Industrial Property Rights Holder
      国立大学法人東京大学
    • Industrial Property Number
      2008-085204
    • Filing Date
      2008-03-28
    • Data Source
      KAKENHI-PROJECT-19209036
  • [Patent] 胚盤胞補完作用を利用した臓器形成2007

    • Inventor(s)
      中内啓光, 臼井丈一, 小林俊寛
    • Industrial Property Rights Holder
      東京大学
    • Industrial Property Number
      2007-042041
    • Filing Date
      2007-02-22
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17209036
  • [Patent] ES 細胞からの造血前駆細胞を内包する構造物、及び該構造物を用いた血球細胞の調整方法2007

    • Inventor(s)
      中内啓光、江藤浩之、高山直也, 錦井秀和, 津久井弘子
    • Industrial Property Rights Holder
      国立大学法人東京大学
    • Filing Date
      2007-10-04
    • Data Source
      KAKENHI-PROJECT-19209036
  • [Patent] キメリズムを利用した幹細胞移植のための検査2006

    • Inventor(s)
      中内啓光, 渡辺信和, 高橋聡, 守田陽平, 山崎聡
    • Industrial Property Rights Holder
      東京大学, 株式会社リプロセル
    • Industrial Property Number
      2006-251856
    • Filing Date
      2006-09-15
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17209036
  • [Patent] ES細胞からの造血前駆細胞を内包する構造物、及び該構造物を用いた血球細胞の調整方法。2006

    • Inventor(s)
      中内啓光, 江藤浩之, 高山直也, 錦井秀和, 津久井弘子
    • Industrial Property Rights Holder
      東京大学
    • Industrial Property Number
      2006-272555
    • Filing Date
      2006-10-04
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17209036
  • [Patent] キメリズムを利用した幹細胞移植のための検査2005

    • Inventor(s)
      中内啓光, 渡辺信和, 高橋聡, 守田陽平, 山崎聡
    • Industrial Property Rights Holder
      東京大学, 株式会社リプロセル
    • Industrial Property Number
      2005-270867
    • Filing Date
      2005-09-16
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17209036
  • [Presentation] ポリマーを用いたヒト臍帯血CD34+細胞の長期培養増幅における酸素濃度の影響2024

    • Author(s)
      岡部 基人、水野 直彬、中内 啓光
    • Organizer
      第46回 日本造血・免疫細胞療法学会総会
    • Data Source
      KAKENHI-PROJECT-20H05695
  • [Presentation] 幹細胞研究から次世代の医療へ:大学から産業界へ2022

    • Author(s)
      中内 啓光
    • Organizer
      筑波大学講義: "Translating Stem Cell Research: From academia to industry”
    • Invited
    • Data Source
      KAKENHI-PROJECT-20H05695
  • [Presentation] Stem cell research and the next generation of transplantation medicine2022

    • Author(s)
      中内 啓光
    • Organizer
      国際移植学会アジアシンポジウム
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H05695
  • [Presentation] 異種移植の今後の展望 基礎科学の進歩が切り開く新しい移植医療2022

    • Author(s)
      中内 啓光
    • Organizer
      日本移植学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20H05695
  • [Presentation] 幹細胞研究から臨床へのトランスレーションを目指して2022

    • Author(s)
      中内 啓光
    • Organizer
      JACI主催勉強会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20H05695
  • [Presentation] Ex vivo expansion of HSCs: towards a holy grail in hematology2021

    • Author(s)
      Hiromitsu Nakauchi
    • Organizer
      Stanford University School of Medicine / 5th Annual Center for Definitive and Curative Medicine (CDCM) Virtual Symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H05695
  • [Presentation] 幹細胞研究から未来の医療へ2020

    • Author(s)
      中内啓光
    • Organizer
      第 27 回日本輸血・細胞治療学会秋季シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-20H05695
  • [Presentation] 幹細胞研究から臨床へのトランスレーションを目指して2020

    • Author(s)
      中内啓光
    • Organizer
      第69回共済医学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20H05695
  • [Presentation] 幹細胞研究から新しい医療へ2020

    • Author(s)
      中内啓光
    • Organizer
      日本口腔外科学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20H05695
  • [Presentation] iPS細胞から臓器をつくる: 国境を跨いだ挑戦2019

    • Author(s)
      中内 啓光
    • Organizer
      NPO健康医療開発機構 細胞医療の時代2018シリーズ 「第7回 細胞移植から臓器移植へ」
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H02661
  • [Presentation] Ex vivo expansion of hematopoietic stem cells: Dream or reality?2019

    • Author(s)
      中内 啓光
    • Organizer
      Prof. Ken-ichi Arai Memorial Symposium
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H02661
  • [Presentation] Clonal analysis of young and aged hematopoietic stem cells2018

    • Author(s)
      Hiromitsu Nakauchi
    • Organizer
      Mini Symposium at Lund University
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H02661
  • [Presentation] Stable ex vivo HSC expansion: dream or reality?2018

    • Author(s)
      Hiromitsu Nakauchi
    • Organizer
      Cambridge Stem Cell Symposium: UK CSCIS Opening Symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H02661
  • [Presentation] Stem Cell Niche: From Cells to Organs2017

    • Author(s)
      中内 啓光
    • Organizer
      Cell Press Lablinks
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H02661
  • [Presentation] 幹細胞ニッチ:細胞から臓器へ~2017

    • Author(s)
      中内 啓光
    • Organizer
      東京免疫フォーラム
    • Place of Presentation
      東京大学医科学研究所、東京
    • Year and Date
      2017-03-23
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H02661
  • [Presentation] 幹細胞とアミノ酸バランス (Stem Cells and Amino Acid Balance)2017

    • Author(s)
      中内 啓光
    • Organizer
      日本癌学会ランチョンセミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H02661
  • [Presentation] 幹細胞ニッチ:細胞から臓器へ2017

    • Author(s)
      中内 啓光
    • Organizer
      東京免疫フォーラム
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H02661
  • [Presentation] Clonal Analysis of Young and Aged Hematopoietic Stem Cells2017

    • Author(s)
      Hiromitsu Nakauchi
    • Organizer
      Regenerative Medicine Seminar Series (ReMS)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H02661
  • [Presentation] 幹細胞ニッチの概念を利用した新しい医療2017

    • Author(s)
      中内 啓光
    • Organizer
      第9回血液疾患免疫療法学会学術集会共催ランチョンセミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H02661
  • [Presentation] Stem Cell Niche-From Cells to Organs2016

    • Author(s)
      Hiromitsu Nakauchi
    • Organizer
      University of Southern California
    • Place of Presentation
      Los Angeles, California,USA
    • Year and Date
      2016-05-17
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H02661
  • [Presentation] From Stem Cells to Organs: Exploiting the organ niche for interspecific organogenesis2016

    • Author(s)
      Hiromitsu Nakauchi
    • Organizer
      Advances in Organogenesis and Tissue Engineering Symposia at John Hopkins University
    • Place of Presentation
      Baltimore, Maryland,USA
    • Year and Date
      2016-05-25
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H02661
  • [Presentation] Novel cancer immunotherapy utilizing iPS cell technology2016

    • Author(s)
      Hiromitsu Nakauchi
    • Organizer
      Siebel Stem Cell Symposium
    • Place of Presentation
      Stanford, CA, USA
    • Year and Date
      2016-01-20
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-23106004
  • [Presentation] Stem cell niche" from cells and organs2016

    • Author(s)
      Hiromitsu Nakauchi
    • Organizer
      Stower’s Li Lab
    • Place of Presentation
      Kansas City, Missouri,USA
    • Year and Date
      2016-05-04
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H02661
  • [Presentation] Stem Cell niche--from cells to organs2016

    • Author(s)
      Hiromitsu Nakauchi
    • Organizer
      7th Annual Stem Cell Biology and Regenerative Medicine Retreat
    • Place of Presentation
      Monterey, California,USA
    • Year and Date
      2016-09-27
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H02661
  • [Presentation] From Stem Cells to Organs: Exploiting the organ niche for interspecies organogenesis2016

    • Author(s)
      Hiromitsu Nakauchi
    • Organizer
      Erasmus MC workshop
    • Place of Presentation
      Rotterdam, Netherland
    • Year and Date
      2016-11-23
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H02661
  • [Presentation] Generation of Functional Organs by Way of Interspecific Blastocyst Complementation2016

    • Author(s)
      Hiromitsu Nakauchi
    • Organizer
      Keystone Symposium
    • Place of Presentation
      Keystone, Colorado, USA
    • Year and Date
      2016-03-14
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-23106004
  • [Presentation] Stem cell niche for cells and organs2016

    • Author(s)
      Hiromitsu Nakauchi
    • Organizer
      Baxter Lab Retreat
    • Place of Presentation
      Menlo Park, CA, USA
    • Year and Date
      2016-01-20
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-23106004
  • [Presentation] “Organs, not Cells” Generation of Functional Organs from iPS Cells via Interspecies Blastocyst Complementation2015

    • Author(s)
      Hiromitsu Nakauchi
    • Organizer
      Chinese Bioscience Association (CBA)
    • Place of Presentation
      Foster City, CA, USA
    • Year and Date
      2015-10-15
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-23106004
  • [Presentation] “Stem Cell Niche” From Cells to Organs and Beyond.”2015

    • Author(s)
      Hiromitsu Nakauchi
    • Organizer
      Cincinnati Children's Hospital Research Foundation
    • Place of Presentation
      Cincinnati, OH, USA
    • Year and Date
      2015-10-07
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-23106004
  • [Presentation] “Stem Cell Niche” From Cells to Organs and Beyond2015

    • Author(s)
      Hiromitsu Nakauchi
    • Organizer
      ISSCR
    • Place of Presentation
      Stockholm, Sweden.
    • Year and Date
      2015-06-24
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-23106004
  • [Presentation] Organ niches and developmental complementation for generation of functional organs in vivo2015

    • Author(s)
      Hiromitsu Nakauchi
    • Organizer
      8th International Meeting of the Stem Cell Network North Rhine Westphalia
    • Place of Presentation
      Bonn, Germany
    • Year and Date
      2015-04-21
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-23106004
  • [Presentation] Generation of functional organs from iPS cells2015

    • Author(s)
      Hiromitsu Nakauchi
    • Organizer
      UC Santa Barbara lecture series
    • Place of Presentation
      Santa Barbara, CA, USA
    • Year and Date
      2015-05-05
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-23106004
  • [Presentation] Growing New Organ in vivo2015

    • Author(s)
      Hiromitsu Nakauchi
    • Organizer
      ESOT
    • Place of Presentation
      Brussels, Belgium.
    • Year and Date
      2015-09-15
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-23106004
  • [Presentation] Dietary created niche for non-myeloablative hematopoietic stem cell transplantation2015

    • Author(s)
      Hiromitsu Nakauchi
    • Organizer
      International Society for Experimental Hematology (ISEH) 44th Annual Scientific Meeting
    • Place of Presentation
      京都国際会館(京都府京都市)
    • Year and Date
      2015-09-18
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-23106004
  • [Presentation] Generation of funcitonal organs in xenogeneic host using conceptus complementation2015

    • Author(s)
      Hiromitsu Nakauchi
    • Organizer
      Recombinetics' Science Advisory Board
    • Place of Presentation
      Vieques, Puerto Rico
    • Year and Date
      2015-05-16
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-23106004
  • [Presentation] Generation of Functional Organs from Pluripotent Stem Cells2015

    • Author(s)
      Hiromitsu Nakauchi
    • Organizer
      University of Hawaii, the Institute for Biogenesis Research and the Office of Technology Transfer & Economic Development (IBR-OTTED) symposium
    • Place of Presentation
      Honolulu, Hawaii, USA
    • Year and Date
      2015-08-05
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-23106004
  • [Presentation] Organs, not Cells: Toward the next generation of regenerative medicine2015

    • Author(s)
      Hiromitsu Nakauchi
    • Organizer
      Hydra XI Summer School
    • Place of Presentation
      Hydra, Greece
    • Year and Date
      2015-09-12
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-23106004
  • [Presentation] Inter-species blastocyst complementation2015

    • Author(s)
      Hiromitsu Nakauchi
    • Organizer
      TRANSGENIC ANIMAL RESEARCH CONFERENCE X (TARC)
    • Place of Presentation
      Tahoe City, CA, USA
    • Year and Date
      2015-08-12
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-23106004
  • [Presentation] In vivo generation of hematopoietic stem cells from iPSCs2014

    • Author(s)
      Hiromitsu Nakauchi
    • Organizer
      JST-CIHR Epigenetics F2F Meeting
    • Place of Presentation
      Toronto, Canada
    • Year and Date
      2014-10-29
    • Invited
    • Data Source
      KAKENHI-PROJECT-24249056
  • [Presentation] Single cell transplantation and clonal analysis of hematopoietic stem cells: Exploring heterogeneity and hierarchy2014

    • Author(s)
      Hiromitsu Nakauchi
    • Organizer
      Till&McCulloch Meetings
    • Place of Presentation
      Ottawa, Canada
    • Year and Date
      2014-10-29
    • Invited
    • Data Source
      KAKENHI-PROJECT-24249056
  • [Presentation] In Vivo Clonal Analysis of Hematopoietic Stem Cells Unveils Novel Myeloid Bypass Differentiation Pathways.2013

    • Author(s)
      Hiromitsu Nakauchi
    • Organizer
      2013 USA-Japan Science Conference
    • Place of Presentation
      Hawaii, USA
    • Invited
    • Data Source
      KAKENHI-PROJECT-24249056
  • [Presentation] In Vivo Clonal Analysis of Hematopoietic Stem Cells Unveils Novel Myeloid Bypass Differentiation Pathways.2013

    • Author(s)
      Hiromitsu Nakauchi
    • Organizer
      2013 USA-Japan Science Conference
    • Place of Presentation
      Hawaii USA
    • Year and Date
      2013-03-24
    • Invited
    • Data Source
      KAKENHI-PLANNED-23106004
  • [Presentation] "Novel non-stepwise early differentiation pathways of HSCs revealed by 5-lineage in vivo tracing"2013

    • Author(s)
      Hiromitsu Nakauchi
    • Organizer
      Gordon Research Conference “Stem Cells & Cancer”
    • Place of Presentation
      Les Diablerets, Switzerland
    • Invited
    • Data Source
      KAKENHI-PROJECT-24249056
  • [Presentation] "Novel non-stepwise early differentiation pathways of HSCs revealed by 5-lineage in vivo tracing"2013

    • Author(s)
      Hiromitsu Nakauchi
    • Organizer
      Gordon Research Conference “Stem Cells & Cancer”
    • Place of Presentation
      Les Diablerets, Switzerland
    • Invited
    • Data Source
      KAKENHI-PLANNED-23106004
  • [Presentation] iPS technology and its future therapeutic potentials.2012

    • Author(s)
      Hiromitsu Nakauchi
    • Organizer
      The Sanger Institute
    • Place of Presentation
      Cambridge, England
    • Invited
    • Data Source
      KAKENHI-PROJECT-24249056
  • [Presentation] Stem cell biology and its potentials for future medicine.2012

    • Author(s)
      Hiromitsu Nakauchi
    • Organizer
      University of Zurich
    • Place of Presentation
      Zurich, Switzerland
    • Invited
    • Data Source
      KAKENHI-PROJECT-24249056
  • [Presentation] iPS technology and its potential for future medicine.2012

    • Author(s)
      Hiromitsu Nakauchi
    • Organizer
      The Babraham Institute
    • Place of Presentation
      Cambridge, England
    • Invited
    • Data Source
      KAKENHI-PROJECT-24249056
  • [Presentation] Non-myelinating Schwann cells in the mouse bone marrow niche maintain hematopoietic stem cell hibernation through TGF-β signaling.2012

    • Author(s)
      Hiromitsu Nakauchi
    • Organizer
      Cold Spring Harbor Asia Conferences
    • Place of Presentation
      Suzhou, China
    • Year and Date
      2012-12-03
    • Invited
    • Data Source
      KAKENHI-PLANNED-23106004
  • [Presentation] Non-myelinating Schwann cells in the mouse bone marrow niche maintain hematopoietic stem cell hibernation through TGF-β signaling.2012

    • Author(s)
      Hiromitsu Nakauchi
    • Organizer
      Cold Spring Harbor Asia Conferences
    • Place of Presentation
      Suzhou, China
    • Invited
    • Data Source
      KAKENHI-PROJECT-24249056
  • [Presentation] iPS technology and its future therapeutic potentials.2012

    • Author(s)
      Hiromitsu Nakauchi
    • Organizer
      The 5th Dutch Society for Stem Cell Research Meeting (DSSCR)
    • Place of Presentation
      Amsterdam, Holland
    • Invited
    • Data Source
      KAKENHI-PROJECT-24249056
  • [Presentation] iPS technology and its future therapeutic potentials.2012

    • Author(s)
      Hiromitsu Nakauchi
    • Organizer
      The 5th Dutch Society for Stem Cell Research Meeting (DSSCR)
    • Place of Presentation
      Amsterdam, Holland
    • Year and Date
      2012-04-11
    • Invited
    • Data Source
      KAKENHI-PLANNED-23106004
  • [Presentation] Stem cell biology and its potentials for future medicine.2012

    • Author(s)
      Hiromitsu Nakauchi
    • Organizer
      University of Zurich
    • Place of Presentation
      Zurich, Switzerland
    • Invited
    • Data Source
      KAKENHI-PLANNED-23106004
  • [Presentation] iPS technology and its potential for future medicine.2012

    • Author(s)
      Hiromitsu Nakauchi
    • Organizer
      The Babraham Institute
    • Place of Presentation
      Cambridge, England
    • Invited
    • Data Source
      KAKENHI-PLANNED-23106004
  • [Presentation] iPS technology and its future therapeutic potentials.2012

    • Author(s)
      Hiromitsu Nakauchi
    • Organizer
      The Sanger Institute
    • Place of Presentation
      Cambridge, England
    • Invited
    • Data Source
      KAKENHI-PLANNED-23106004
  • [Presentation] iPS technology and its potential for future medicine.2012

    • Author(s)
      Hiromitsu Nakauchi
    • Organizer
      University of Geneva Hospital
    • Place of Presentation
      Geneva, Switzerland
    • Invited
    • Data Source
      KAKENHI-PLANNED-23106004
  • [Presentation] Hibernation of Hematopoietic Stem Cells in the Bone Marrow Niche.2012

    • Author(s)
      Hiromitsu Nakauchi
    • Organizer
      The University of Edinburgh
    • Place of Presentation
      Edinburgh, England
    • Invited
    • Data Source
      KAKENHI-PLANNED-23106004
  • [Presentation] Hibernation of Hematopoietic Stem Cells in the Bone Marrow Niche.2012

    • Author(s)
      Hiromitsu Nakauchi
    • Organizer
      The University of Edinburgh
    • Place of Presentation
      Edinburgh, England
    • Invited
    • Data Source
      KAKENHI-PROJECT-24249056
  • [Presentation] Generation of functional organs from pluripotent stem cells.2012

    • Author(s)
      Hiromitsu Nakauchi
    • Organizer
      Lecture Theatre, Department of Biochemistry, Cambridge Stem Cell Club
    • Place of Presentation
      Cambridge, England
    • Invited
    • Data Source
      KAKENHI-PROJECT-24249056
  • [Presentation] Generation of functional organs from pluripotent stem cells.2012

    • Author(s)
      Hiromitsu Nakauchi
    • Organizer
      ISSCR 10th Annual Meeting
    • Place of Presentation
      Yokohama, Japan
    • Invited
    • Data Source
      KAKENHI-PROJECT-24249056
  • [Presentation] Glial cell regulation of hematopoietic stem cell hibernation in the bone marrow niche.2012

    • Author(s)
      Hiromitsu Nakauchi
    • Organizer
      ESGCT/SFTCG Congress
    • Place of Presentation
      Versailles, France
    • Year and Date
      2012-10-27
    • Invited
    • Data Source
      KAKENHI-PLANNED-23106004
  • [Presentation] Glial cell regulation of hematopoietic stem cell hibernation in the bone marrow niche.2012

    • Author(s)
      Hiromitsu Nakauchi
    • Organizer
      ESGCT/SFTCG Congress
    • Place of Presentation
      Versailles, France
    • Invited
    • Data Source
      KAKENHI-PROJECT-24249056
  • [Presentation] Isolation, Clonal Characterization and Hibernation of Hematopoietic Stem Cells.2012

    • Author(s)
      Hiromitsu Nakauchi
    • Organizer
      Wellcome Trust Centre for Stem Cell Research, University of Cambridge
    • Place of Presentation
      Cambridge, England
    • Invited
    • Data Source
      KAKENHI-PLANNED-23106004
  • [Presentation] Stem Cell Niche and TGF-beta signaling.2012

    • Author(s)
      Hiromitsu Nakauchi
    • Organizer
      EMBL Conference, Stem Cells in Cancer and Regenerative Medicine
    • Place of Presentation
      Edinburgh, England
    • Invited
    • Data Source
      KAKENHI-PROJECT-24249056
  • [Presentation] Generation of functional organs from pluripotent stem cells.2012

    • Author(s)
      Hiromitsu Nakauchi
    • Organizer
      Lecture Theatre, Department of Biochemistry, Cambridge Stem Cell Club
    • Place of Presentation
      Cambridge, England
    • Invited
    • Data Source
      KAKENHI-PLANNED-23106004
  • [Presentation] Rat-mouse interspecific chimeras for study of organogenesis and elucidation of xenogenic barrier.2012

    • Author(s)
      Hiromitsu Nakauchi
    • Organizer
      Joint meeting of ISD and NIRM
    • Place of Presentation
      Amsterdam, Netherland
    • Invited
    • Data Source
      KAKENHI-PROJECT-24249056
  • [Presentation] Stem Cell Niche and TGF-beta signaling.2012

    • Author(s)
      Hiromitsu Nakauchi
    • Organizer
      EMBL Conference, Stem Cells in Cancer and Regenerative Medicine
    • Place of Presentation
      Heidelberg, Germany
    • Year and Date
      2012-08-29
    • Invited
    • Data Source
      KAKENHI-PLANNED-23106004
  • [Presentation] Generation of Functional organs from pluripotent stem cells: Toward the next generation of regenerative medicine.2012

    • Author(s)
      Hiromitsu Nakauchi
    • Organizer
      ISSCR 10th Annual Meeting
    • Place of Presentation
      横浜、日本
    • Year and Date
      2012-06-13
    • Invited
    • Data Source
      KAKENHI-PLANNED-23106004
  • [Presentation] iPS technology and its potential for future medicine.2012

    • Author(s)
      Hiromitsu Nakauchi
    • Organizer
      University of Geneva Hospital
    • Place of Presentation
      Geneva, Switzerland
    • Invited
    • Data Source
      KAKENHI-PROJECT-24249056
  • [Presentation] Isolation, Clonal Characterization and Hibernation of Hematopoietic Stem Cells.2012

    • Author(s)
      Hiromitsu Nakauchi
    • Organizer
      Wellcome Trust Centre for Stem Cell Research, University of Cambridge
    • Place of Presentation
      Cambridge, England
    • Invited
    • Data Source
      KAKENHI-PROJECT-24249056
  • [Presentation] Suppressed Neutrophil Development in Hematopoiesis of Induced Pluripotent Stem Cells Derived From a Severe Congenital Neutropenia Patient with ELA2 Mutation2011

    • Author(s)
      Takafumi Hiramoto, Yasuhiro Ebihara, Yoko Mizoguchi, Kazuhiro Nakamura, Shinji Mochizuki, Shohei Yamamoto, Emiko Matsuzaka, Sachiyo Hanada, Ryoko Ohnishi, Kenzaburo Tani, Koji Eto, Hiromitsu Nakauchi, Masao Kobayashi, Kohichiro Tsuji
    • Organizer
      53rd ASH Annual Meeting and Exposition
    • Place of Presentation
      San Diego, USA(oral)
    • Data Source
      KAKENHI-PLANNED-23106004
  • [Presentation] Replicative senescence of hematopoietic stem cells after single cell transplantation2011

    • Author(s)
      Hiromitsu Nakauchi
    • Organizer
      3rd Else Kroner-Fresenius Symposium on Molecular Mechanisms of Stem Cell Aging
    • Place of Presentation
      Ulm, Germany(招待講演)
    • Year and Date
      2011-05-20
    • Data Source
      KAKENHI-PROJECT-21249059
  • [Presentation] Nov/CCN3 Enhances Long-Term Repopulating Activity of Mouse Hematopoietic Stem Cells Via Intergin β3 Signaling Collaborating with Thrombopoietin2011

    • Author(s)
      Jun Ishihara, Terumasa Umemoto, Masayuki Yamato, Yoshiko Shiratsuchi, Brian G.Petrich, Hiromitsu Nakauchi, Koji Eto, Toshio Kitamura, Teruo Okano
    • Organizer
      53rd ASH Annual Meeting and Exposition
    • Place of Presentation
      San Diego, USA(oral)
    • Data Source
      KAKENHI-PLANNED-23106004
  • [Presentation] Non-myelinating Schwann cells in the mouse bone marrow niche maintain hematopoietic stem cell hibernation through TGF-b signaling2011

    • Author(s)
      Hiromitsu Nakauchi
    • Organizer
      The Oklahoma Center for Adult Stem Cell Research (OCASCR)
    • Place of Presentation
      Oklahoma, USA(招待講演)
    • Year and Date
      2011-06-14
    • Data Source
      KAKENHI-PROJECT-21249059
  • [Presentation] 3^<rd> Else Kroner-Fresenius Symposium on Molecular Mechanisms of Stem Cell Aging2011

    • Author(s)
      Hiromitsu Nakauchi
    • Place of Presentation
      Germany
    • Year and Date
      2011-04-01
    • Data Source
      KAKENHI-PROJECT-21249059
  • [Presentation] Non-myelinating schwann cells in the mouse bone marrow niche maintain hematopoietic stem cell hibernation through TGF-beta signaling2011

    • Author(s)
      Hiromitsu Nakauchi
    • Organizer
      Keystone Symposia
    • Place of Presentation
      Keystone, USA(招待講演)
    • Year and Date
      2011-04-01
    • Data Source
      KAKENHI-PROJECT-22659058
  • [Presentation] Non-myelinating Schwann cells in the mouse bone marrow niche maintain hematopoietic stem cell hibernation through TGF-b signaling2011

    • Author(s)
      Hiromitsu Nakauchi
    • Organizer
      The Oklahoma Center for Adult Stem Cell Research(OCASCR)
    • Place of Presentation
      USA
    • Year and Date
      2011-05-20
    • Data Source
      KAKENHI-PROJECT-21249059
  • [Presentation] Generation of Rat Pancreas in Mouse : toward the next generation of regenerative medicine2011

    • Author(s)
      Hiromitsu Nakauchi
    • Organizer
      ESHG Symposium
    • Place of Presentation
      Amsterdam, Holland(招待講演)
    • Year and Date
      2011-05-29
    • Data Source
      KAKENHI-PROJECT-22659058
  • [Presentation] Generation of Rat Pancreas in Mouse : toward the next generation of regenerative medicine2011

    • Author(s)
      Hiromitsu Nakauchi
    • Organizer
      ESHG Symposium
    • Place of Presentation
      Amsterdam, Holland(招待講演)
    • Year and Date
      2011-05-29
    • Data Source
      KAKENHI-PROJECT-21249059
  • [Presentation] Non-myelinating schwann cells in the mouse bone marrow niche maintain hematopoietic stem cell hibernation through TGF-beta signaling2011

    • Author(s)
      Hiromitsu Nakauchi
    • Organizer
      Keystone Symposia
    • Place of Presentation
      Keystone, USA(招待講演)
    • Year and Date
      2011-04-01
    • Data Source
      KAKENHI-PROJECT-21249059
  • [Presentation] Direct and Continuous Inhibition of ADAM17 Using a Novel Selective Inhibitor Restores Functional Platelet Yield From Human Pluripotent Stem Cells2011

    • Author(s)
      Shinji Hirata, Ryoko Jono-Ohnishi, Satoshi Nishimura. Naoya Takayama, Sou Nakamura, Hiromitsu Nakauchi, Takahiko Murata, Koji Eto
    • Organizer
      53rd ASH Annual Meeting and Exposition
    • Place of Presentation
      San Diego, USA(poster)
    • Data Source
      KAKENHI-PLANNED-23106004
  • [Presentation] Generation of functional organs from iPS cells2011

    • Author(s)
      Hiromitsu Nakauchi
    • Organizer
      12th International Congress on Reproductive Biomedicine & 7th International Congress on Stem Cell Biology and Technology
    • Place of Presentation
      Tehran, Iran(招待講演)
    • Year and Date
      2011-09-07
    • Data Source
      KAKENHI-PROJECT-21249059
  • [Presentation] Non-myelinating Schwann cells in the mouse bone marrow niche maintain hematopoietic stem cell hibernation through TGF-b signaling2011

    • Author(s)
      Hiromitsu Nakauchi
    • Organizer
      The Oklahoma Center for Adult Stem Cell Research(OCASCR)
    • Place of Presentation
      Oklahoma, USA
    • Year and Date
      2011-06-14
    • Data Source
      KAKENHI-PROJECT-22659058
  • [Presentation] Non-myelinating schwann cells in the mouse bone marrow niche maintain hematopoietic stem cell hibernation through TGF-beta signaling2011

    • Author(s)
      Hiromitsu Nakauchi
    • Organizer
      Keystone Symposia
    • Place of Presentation
      USA
    • Year and Date
      2011-06-14
    • Data Source
      KAKENHI-PROJECT-21249059
  • [Presentation] Generation of functional organs from pluripotent stem cells2011

    • Author(s)
      Hiromitsu Nakauchi
    • Organizer
      Cold Spring Harbor Conferences Asia & ISSCR
    • Place of Presentation
      蘇州、中国(招待講演)
    • Year and Date
      2011-10-26
    • Data Source
      KAKENHI-PROJECT-21249059
  • [Presentation] Non-myelinating schwann cells in the mouse bone marrow niche maintain hematopoietic stem cell hibernation through TGF-beta signaling2011

    • Author(s)
      Hiromitsu Nakauchi
    • Organizer
      Keystone Symposia
    • Place of Presentation
      Keystone, USA
    • Year and Date
      2011-04-01
    • Data Source
      KAKENHI-PROJECT-22659058
  • [Presentation] Platelet Production System Using an Immortalized Megakaryocyte Cell Line Derived From Human Pluripotent Stem Cells2011

    • Author(s)
      Sou Nakamura, Naoya Takayama, Hiromitsu Nakauchi, Koji Eto
    • Organizer
      53rd ASH Annual Meeting and Exposition (plenary session)
    • Place of Presentation
      San Diego, USA
    • Data Source
      KAKENHI-PLANNED-23106004
  • [Presentation] Generation of functional organs from iPS cells2011

    • Author(s)
      Hiromitsu Nakauchi
    • Organizer
      12th International Congress on Reproductive Biomedicine & 7th International Congress on Stem Cell Biology and Technology
    • Place of Presentation
      Tehran, Iran(招待講演)
    • Year and Date
      2011-09-07
    • Data Source
      KAKENHI-PLANNED-23106004
  • [Presentation] Non-myelinating Schwann cells in the mouse bone marrow niche maintain hematopoietic stem cell hibernation through TGF-b signaling2011

    • Author(s)
      Hiromitsu Nakauchi
    • Organizer
      The Oklahoma Center for Adult Stem Cell Research (OCASCR)
    • Place of Presentation
      Oklahoma, USA(招待講演)
    • Year and Date
      2011-06-14
    • Data Source
      KAKENHI-PROJECT-22659058
  • [Presentation] Generation of functional organs from iPS cells2011

    • Author(s)
      Hiromitsu Nakauchi
    • Organizer
      12th International Congress on Reproductive Biomedicine & 7th International Congress on Stem Cell Biology and Technology
    • Place of Presentation
      Suzhou, China
    • Year and Date
      2011-09-07
    • Data Source
      KAKENHI-PROJECT-22659058
  • [Presentation] Replicative senescence of hematopoietic stem cells after single cell transplantation2011

    • Author(s)
      Hiromitsu Nakauchi
    • Organizer
      3rd Else Kroner-Fresenius Symposium on Molecular Mechanisms of Stem Cell Aging
    • Place of Presentation
      Ulm, Germany
    • Year and Date
      2011-05-20
    • Data Source
      KAKENHI-PROJECT-22659058
  • [Presentation] Stepwise Signaling and Low Oxygen Promote Hematopoietic Progenitor Emergence From Human Pluripotent Stem Cells2011

    • Author(s)
      Hiroshi Endo, Naoya Takayama, Tomo Koike, Hiromitsu Nakauchi, Koji Eto
    • Organizer
      53rd ASH Annual Meeting and Exposition
    • Place of Presentation
      San Diego, USA(poster)
    • Data Source
      KAKENHI-PLANNED-23106004
  • [Presentation] Modeling Congenital Amegakaryocytic Thrombocytopenia Using Patient-Specific Induced Pluripotent Stem Cells2011

    • Author(s)
      Naoya Takayama, Shinji Hirata, Ryoko Jono-Ohnishi, Sou Nakamura, Sho-ichi Hirose, Hiroshi Endo, Masanori Nishi, Yuhei Hamazaki, Shin Kaneko, Eiichi Ishii, Hiromitsu Nakauchi, Shinji Kunishima, Koji Eto
    • Organizer
      53rd ASH Annual Meeting and Exposition
    • Place of Presentation
      San Diego, USA(oral)
    • Data Source
      KAKENHI-PLANNED-23106004
  • [Presentation] Generation of Rat Pancreas in Mouse : toward the next generation of regenerative medicine2011

    • Author(s)
      Hiromitsu Nakauchi
    • Organizer
      ESHG Symposium
    • Place of Presentation
      Amsterdam, Holland
    • Year and Date
      2011-05-29
    • Data Source
      KAKENHI-PROJECT-22659058
  • [Presentation] Replicative senescence of hematopoietic stem cells after single cell transplantation2011

    • Author(s)
      Hiromitsu Nakauchi
    • Organizer
      3rd Else Kroner-Fresenius Symposium on Molecular Mechanisms of Stem Cell Aging
    • Place of Presentation
      Ulm, Germany(招待講演)
    • Year and Date
      2011-05-20
    • Data Source
      KAKENHI-PROJECT-22659058
  • [Presentation] Generation of functional organs from pluripotent stem cells2011

    • Author(s)
      Hiromitsu Nakauchi
    • Organizer
      Cold Spring Harbor Conferences Asia & ISSCR
    • Place of Presentation
      Tehran, Iran
    • Year and Date
      2011-10-26
    • Data Source
      KAKENHI-PROJECT-22659058
  • [Presentation] In Vitro Generation of Mature T Lymphocytes From Human Ips Cells and Genetic Analysis of TCR Gene Rearrangements2011

    • Author(s)
      Toshinobu Nishimura, Shin Kaneko, Yoko Tajima, Naoya Takayama, Ai Tachikawa-Kawana, Koji Eto, Hiromitsu Nakauchi
    • Organizer
      53rd ASH Annual Meeting and Exposition
    • Place of Presentation
      San Diego, USA(poster)
    • Data Source
      KAKENHI-PLANNED-23106004
  • [Presentation] Generation of functional organs from pluripotent stem cells2011

    • Author(s)
      Hiromitsu Nakauchi
    • Organizer
      Cold Spring Harbor Conferences Asia & ISSCR
    • Place of Presentation
      蘇州、中国(招待講演)
    • Year and Date
      2011-10-26
    • Data Source
      KAKENHI-PROJECT-22659058
  • [Presentation] Generation of functional organs from iPS cells2011

    • Author(s)
      Hiromitsu Nakauchi
    • Organizer
      12th International Congress on Reproductive Biomedicine & 7th International Congress on Stem Cell Biology and Technology
    • Place of Presentation
      Tehran, Iran(招待講演)
    • Year and Date
      2011-09-07
    • Data Source
      KAKENHI-PROJECT-22659058
  • [Presentation] Platelet transfusion system using an immortalized megakaryocyte cell line derived from hESCs/iPSCs2011

    • Author(s)
      Sou Nakamura, Naoya Takayama, Hiromitsu Nakauchi, Koji Eto
    • Organizer
      第73回日本血液学会学術集会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PLANNED-23106004
  • [Presentation] Generation of functional organs from pluripotent stem cells2011

    • Author(s)
      Hiromitsu Nakauchi
    • Organizer
      Cold Spring Harbor Conferences Asia & ISSCR
    • Place of Presentation
      蘇州、中国(招待講演)
    • Year and Date
      2011-10-26
    • Data Source
      KAKENHI-PLANNED-23106004
  • [Presentation] Heterogeneity and a hierarchy within the most primitive hematopoietic stem cell compartment2009

    • Author(s)
      Hiromitsu Nakauchi
    • Organizer
      Symposium on Molecular Mechanisms of Adult Stem cell Aging
    • Place of Presentation
      Germany
    • Data Source
      KAKENHI-PROJECT-21249059
  • [Presentation] Molecular reguration of hematopoetic stemcell self-renewal and dormancy2009

    • Author(s)
      中内啓光
    • Organizer
      International PhD Prgram in Immunology, Cell Biology and Biochemistry 2008-2009 Lecture Course
    • Place of Presentation
      Switzerlamd, Bellinzona
    • Year and Date
      2009-05-28
    • Data Source
      KAKENHI-PROJECT-21249059
  • [Presentation] Three-year clinical follow-up of 5 patients treated with suicide gene modified donor lymphocyte infusion therapy in Japan2009

    • Author(s)
      金子新、Y.Ohkokshi、大津真、N.Nemoto、T.Nanmoku、Kazumi Suzukawa、Y.Hasegawa、H.Kojima、T.Fukushima、R.Sumazaki、小野寺雅史、Y.Harada、H.Sakamaki、M.Tsuchida、S.Kato、C.Bonini、C.Bordignon、S.Chiba、中内啓光、T.Nakasawa
    • Organizer
      第15回日本遺伝子治療学会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-21249059
  • [Presentation] tPA regulates bone marrow derived cell dependent neoangiogenesis during tissue regeneration2009

    • Author(s)
      Koichi Hattori(服部先生)、Makiko Ohki、Yuichi Ohki、Chiemi Nishida、Makoto Ishihara、Yoshihiko Tashiro、Ismael Gritli、中内啓光、Beate Heissig
    • Organizer
      第71回日本血液学会学術総会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-21249059
  • [Presentation] SINGLE-CELL TRANSPLANTATION AND CLONAL ANALYSIS OF HEMATOPOIETIC STEM CELLS : EXPLORING HETEROGENEITY AND HIERARCHY2009

    • Author(s)
      中内啓光
    • Organizer
      The 2009 ISEH Donald Metclaf Lecture Award
    • Place of Presentation
      Athens, Greece
    • Data Source
      KAKENHI-PROJECT-21249059
  • [Presentation] Generation of organs from pluripotent stem cells.2009

    • Author(s)
      中内啓光
    • Organizer
      Abcam Stem Cells 2009
    • Place of Presentation
      Antigua/Balbuda
    • Data Source
      KAKENHI-PROJECT-21249059
  • [Presentation] What's 'blood donation?'A question from the future2009

    • Author(s)
      中内啓光
    • Organizer
      第71回日本血液学会学術総会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-21249059
  • [Presentation] Single-cell transplantation and clonal analysis of hematopoietic stem cells : Exploring heterogeneity and hierarchy2009

    • Author(s)
      Hiromitsu Nakauchi
    • Organizer
      The 2009 ISEH(ISEH : International Society for Experimental Hematology) Donald Metclaf Lecture Award
    • Place of Presentation
      Greece
    • Data Source
      KAKENHI-PROJECT-21249059
  • [Presentation] HSC Hierarchy of hematopoietic stem cells2009

    • Author(s)
      Nakauchi H.
    • Organizer
      USA-JapanCooperative Cancer Workshop "Stem Cells inNormal and Malignant Hematopoiesis(Invited Speaker)
    • Place of Presentation
      Hawaii, USA
    • Data Source
      KAKENHI-PROJECT-19209036
  • [Presentation] iPS細胞研究の進展と臨床応用への期待2009

    • Author(s)
      中内啓光
    • Organizer
      第9回日本再生医療学会総会
    • Place of Presentation
      広島
    • Data Source
      KAKENHI-PROJECT-21249059
  • [Presentation] What's' blood donation'? A question from the future2009

    • Author(s)
      Hiromitsu Nakauchi
    • Organizer
      第71回日本血液学会総会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-21249059
  • [Presentation] Analysis of Signaling Eventsin hematopetic Stem Cells, a Vary rarePopulation in the Bone Marrow2009

    • Author(s)
      Nakauchi H
    • Organizer
      34^<th> LorneConference on Protein Structure and Function (Invited Speaker)
    • Place of Presentation
      Eskine Mantra Resort,Lorne Australia
    • Data Source
      KAKENHI-PROJECT-19209036
  • [Presentation] Analysis of Signaling Events in hematopetic Stem Cells, a Vary rare Population in the Bone Marrow.2009

    • Author(s)
      Nakauchi H.
    • Organizer
      34th Lorne Conference on Protein Structure and Function.
    • Place of Presentation
      Eskine Mantra Resort, Lorne Australia
    • Data Source
      KAKENHI-PROJECT-19209036
  • [Presentation] Heterogeneity and a hierarchy within the most primitive hematopoietic stem cell compartment2009

    • Author(s)
      中内啓光
    • Organizer
      Symposium on Molecular Mechanisms of Adult Stem cell Aging.
    • Place of Presentation
      Reinsenburg, Germany
    • Data Source
      KAKENHI-PROJECT-21249059
  • [Presentation] A hierarchy within the most primitive hematopoietic stem cell compartment2009

    • Author(s)
      中内啓光
    • Organizer
      7th Catholic Int.Stem Cell Symposium in Seoul
    • Place of Presentation
      Seoul, Korea
    • Data Source
      KAKENHI-PROJECT-21249059
  • [Presentation] Molecular reguration ofhematopoetic stemcell self-renewal anddormancy2009

    • Author(s)
      Nakauchi H
    • Organizer
      Internatinal PhD Program in Immuology, CellBiology and Biochemistry2008-2009 Lecture Course(Invited Speaker)
    • Place of Presentation
      Switzerland
    • Year and Date
      2009-05-28
    • Data Source
      KAKENHI-PROJECT-19209036
  • [Presentation] Symposium on MolecularMechanisms of Adult Stem cell Aging2009

    • Author(s)
      Nakauchi H
    • Organizer
      Heterogeneity and a hierarchy within themost primitive hematopoietic stem cellcompartment
    • Place of Presentation
      Reisensburg ,Germany
    • Data Source
      KAKENHI-PROJECT-19209036
  • [Presentation] Generation of functionalplatelets from human pluripotent stem cells invitro2008

    • Author(s)
      Nakauchi H
    • Organizer
      2008 TREMIS-AP Chapter Meeting (Invited Speaker)
    • Place of Presentation
      Taipei
    • Data Source
      KAKENHI-PROJECT-19209036
  • [Presentation] TGF-βas a Candidate BoneMarrow Niche Signal to induce Hematopoietic Stem Cell Hibernation2008

    • Author(s)
      Nakauchi H
    • Organizer
      ISEH2008 Meeting Invited Speaker
    • Place of Presentation
      Boston, U.S.A
    • Data Source
      KAKENHI-PROJECT-19209036
  • [Presentation] TGF-βas a candidate bonemarrow niche signal to induce hematopoieticstem cell hibernation2008

    • Author(s)
      Nakauchi H
    • Organizer
      The 5th NikkoInternational Symposium 2008 Invited Speaker
    • Place of Presentation
      Shimotsuke, Tochigi Japan
    • Year and Date
      2008-10-25
    • Data Source
      KAKENHI-PROJECT-19209036
  • [Presentation] Cytokine Signals Modulated ViaLipid Rafts Induce Hibernation inHematopoietic Stem Cells2008

    • Author(s)
      Nakauchi H
    • Organizer
      InternationalSociety for Stem Cell Research 6th AnnualMeeting (ISSCR)Invited Speaker
    • Place of Presentation
      Philadelphia, U.S.A.
    • Data Source
      KAKENHI-PROJECT-19209036
  • [Presentation] Next generation regenerative medicine: From cell therapy to organ replacement therapy2008

    • Author(s)
      Nakauchi H.
    • Organizer
      The 10^<th> Anniversary celebration of Korean Tissue Engineering and Regenerative Medicine Society (TERMIS)
    • Place of Presentation
      Seoul, Korea
    • Data Source
      KAKENHI-PROJECT-19209036
  • [Presentation] Hibernation of Hematopoietic Stem Cells in the bone marrow niche2008

    • Author(s)
      Nakauchi H.
    • Organizer
      Harvard Stem Cell Institute scminar series.
    • Place of Presentation
      Massachusetts general Hospital, Boston
    • Year and Date
      2008-05-06
    • Data Source
      KAKENHI-PROJECT-19209036
  • [Presentation] Hibernation of hematopoieticstem sells in the bone marrow niche2008

    • Author(s)
      Nakauchi H
    • Organizer
      The9th International Congress on Cell Biology(ICCB 2008) & The 20th Annual Conferenceof the Korean Society for Molecular andCellular Biology (Invited Speaker)
    • Place of Presentation
      Seoul, Korea
    • Data Source
      KAKENHI-PROJECT-19209036
  • [Presentation] Hibernation of HematopoieticStem Cells in the Bone Marrow Niche2008

    • Author(s)
      Nakauchi H
    • Organizer
      13thCongress of the European HematologyAssociation Invited Speaker
    • Place of Presentation
      Copenhagen, Denmark
    • Data Source
      KAKENHI-PROJECT-19209036
  • [Presentation] "Hibemation of Hematopoietic Stem Cells in the Bone Marrow Nich" 13th Congress of the European Hematology Association.2008

    • Author(s)
      Nakauchi H.
    • Organizer
      13th Congress of the European Hematology Association.
    • Place of Presentation
      Copenhagen, Denmark
    • Data Source
      KAKENHI-PROJECT-19209036
  • [Presentation] Hibemation of hematopoietic stem sells in the bone marrow niche2008

    • Author(s)
      Nakauchi H.
    • Organizer
      The 9th International Congress on Cell Biology (ICCB 2008) & The 20th Annual Conference of the Korean Society for Molecular and Cellular Biology.
    • Place of Presentation
      Seoul, Korea
    • Data Source
      KAKENHI-PROJECT-19209036
  • [Presentation] Bone Marrow Niche and Hematopoietic Stem Cell Regulation2008

    • Author(s)
      Nakauchi H.
    • Organizer
      4th Annual CONSERT Meeting
    • Place of Presentation
      Leukerbad, Switzerland
    • Data Source
      KAKENHI-PROJECT-19209036
  • [Presentation] Silencing : Hibernation ofhematopoietic stem cells in the bone marrowniche2008

    • Author(s)
      Nakauchi H
    • Organizer
      Meeting of Barsinghausen
    • Place of Presentation
      Germany
    • Data Source
      KAKENHI-PROJECT-19209036
  • [Presentation] Generation of functional platelets from human Pluripotent stem cells in vitro2008

    • Author(s)
      Nakauchi H.
    • Organizer
      2008 TREMIS-AP Chapter Meeting
    • Place of Presentation
      Taipei
    • Data Source
      KAKENHI-PROJECT-19209036
  • [Presentation] TGF-β as a candidate bone marrow niche signal to induce hematopoietic stem cell hibernation2008

    • Author(s)
      Nakauchi H.
    • Organizer
      The 5th Nikko International Symposium 2008
    • Place of Presentation
      shimotsuke, Tochigi Japan
    • Year and Date
      2008-10-25
    • Data Source
      KAKENHI-PROJECT-19209036
  • [Presentation] TGF-βas a Candidate Bone Marrow Niche Signal to induce Hematopoietic Stem Cell Hibemation.2008

    • Author(s)
      Nakauchi H.
    • Organizer
      ISEH 2008 Meeting
    • Place of Presentation
      Boston, U.S.A.
    • Data Source
      KAKENHI-PROJECT-19209036
  • [Presentation] Cytokine Signals Modulated Via Lipid Rafts Induce Hibernation in Hematopoietic Stem Cells2008

    • Author(s)
      Nakauchi H.
    • Organizer
      International Society for Stem Cell Research 6th Annual Meeting(ISSCR)
    • Place of Presentation
      Philadelphia, U.S.A.
    • Data Source
      KAKENHI-PROJECT-19209036
  • [Presentation] Use of A Developmental Niche to Generative A Kidney From Donor Embrionic Stem Cells2007

    • Author(s)
      Nakauchi H.
    • Organizer
      International Society for Stem Cell Research (ISSCR)5th Annual Meeting
    • Place of Presentation
      Cairns, Australia
    • Data Source
      KAKENHI-PROJECT-19209036
  • [Presentation] Molecular regulation of HSC self-renewal---Hibernation of Hematopoietic Stem Cells in the Bone Marrow Niche---2007

    • Author(s)
      Nakauchi H.
    • Organizer
      Hemato-Oncology Seminar Series 2007 at University Medical Center Groningen
    • Place of Presentation
      The Netherlands
    • Year and Date
      2007-09-05
    • Data Source
      KAKENHI-PROJECT-19209036
  • [Presentation] A Mechanism to Protect Hematopoietic Stem Cells in the Bone Marrow Niche : Implications for Cancer Stem Cells and Cancer Treatment2007

    • Author(s)
      Nakauchi H.
    • Organizer
      Tissue Engineering International & Regenerative Medicine Society Asia-Pacific Chapter Meeting 2007
    • Place of Presentation
      Akasaka, Tokyo Japan
    • Data Source
      KAKENHI-PROJECT-19209036
  • [Presentation] Hibernation of hematopoietic stem cells in the bone marrow niche2007

    • Author(s)
      Nakauchi H.
    • Organizer
      JSPS Core to Core Program Symposium Lund University and Keio University "Collaboration of Research Centers for Stem Cell Biology and Regeneration Medicine"
    • Place of Presentation
      Roppongi, Tokyo, Japan
    • Year and Date
      2007-11-30
    • Data Source
      KAKENHI-PROJECT-19209036
  • [Presentation] Exploring heterogeneity and hierarchy within the most primitive hematopoietic stem cell compartment

    • Author(s)
      中内啓光
    • Organizer
      日本分子生物学会シンポジウム
    • Place of Presentation
      兵庫
    • Invited
    • Data Source
      KAKENHI-PROJECT-24249056
  • [Presentation] The Stem Cell Niche

    • Author(s)
      Hiromitsu Nakauchi
    • Organizer
      Gordon Research Conference
    • Place of Presentation
      Ventura Beach Marriott, Ventura, CA. US
    • Year and Date
      2015-02-15 – 2015-02-20
    • Invited
    • Data Source
      KAKENHI-PROJECT-24249056
  • [Presentation] Generation of functional organs from iPS cells

    • Author(s)
      Hiromitsu Nakauchi
    • Organizer
      NIH-Japan-JSPS Symposium
    • Place of Presentation
      Bethesda, MD, US
    • Year and Date
      2014-10-22 – 2014-10-24
    • Invited
    • Data Source
      KAKENHI-PLANNED-23106004
  • [Presentation] Exploring heterogeneity and hierarchy within the most primitive hematopoietic stem cell compartment

    • Author(s)
      中内啓光
    • Organizer
      日本分子生物学会シンポジウム
    • Place of Presentation
      兵庫
    • Invited
    • Data Source
      KAKENHI-PLANNED-23106004
  • [Presentation] Myeloid-biased hematopoiesis in aged mouse bone marrow

    • Author(s)
      Hiromitsu Nakauchi
    • Organizer
      Japan-US Hematology conference
    • Place of Presentation
      Hawaii, U.S.
    • Year and Date
      2015-03-16 – 2015-03-18
    • Invited
    • Data Source
      KAKENHI-PROJECT-24249056
  • [Presentation] In vivo generation of functional cells and organs from iPSCs

    • Author(s)
      Hiromitsu Nakauchi
    • Organizer
      2014 Bridging Biomedical Worlds
    • Place of Presentation
      Beijing, China
    • Year and Date
      2014-10-13 – 2014-10-15
    • Invited
    • Data Source
      KAKENHI-PLANNED-23106004
  • [Presentation] Organ niches and developmental complementation for generation of functional organs in vivo

    • Author(s)
      Hiromitsu Nakauchi
    • Organizer
      Gordon Research Conference
    • Place of Presentation
      Ventura Beach Marriott, Ventura, CA. US
    • Year and Date
      2015-02-15 – 2015-02-20
    • Invited
    • Data Source
      KAKENHI-PLANNED-23106004
  • []

  • 1.  NAKAMURA Yukiko (60231479)
    # of Collaborated Projects: 23 results
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  • 2.  TOKUMOTO Yasuhito (70261170)
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  • 3.  TANIGUCHI Hideki (70292555)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 2 results
  • 4.  SHIBUYA Akira (80216027)
    # of Collaborated Projects: 7 results
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  • 5.  IWAMA Atsushi (70244126)
    # of Collaborated Projects: 7 results
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  • 6.  KOITO Atsushi (70231305)
    # of Collaborated Projects: 6 results
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  • 7.  SHIBUYA Kazuko (00302406)
    # of Collaborated Projects: 5 results
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  • 8.  HIROCHIKA Rei (90260223)
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  • 9.  ONODERA Masahumi (10334062)
    # of Collaborated Projects: 4 results
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  • 10.  EMA Hideo (50344445)
    # of Collaborated Projects: 4 results
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  • 11.  Eto Koji (50286986)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 18 results
  • 12.  TAKAHAMA Yousuke (20183858)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 13.  SUDA Toshio (60118453)
    # of Collaborated Projects: 3 results
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  • 14.  NAKATHATA Tatsutoshi (20110744)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 15.  TAKADA Yasutsugu (10272197)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 16.  OTSU Makoto (30361330)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 22 results
  • 17.  KANEKO Makoto (70224607)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 18.  FUKUDA Toshio (70156785)
    # of Collaborated Projects: 2 results
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  • 19.  SEKI Minoru (80206622)
    # of Collaborated Projects: 2 results
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  • 20.  MAE Yasushi (50304027)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 21.  HISHIKAWA Keiichi (50255460)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 22.  FUJITA Toshiro (10114125)
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  • 23.  OKUMURA Ko (50009700)
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  • 24.  YAGITA Hideo (30182306)
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  • 25.  KUMAGAI Yoshihiro (80175314)
    # of Collaborated Projects: 2 results
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  • 26.  深尾 立 (50091921)
    # of Collaborated Projects: 2 results
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  • 27.  水野 直彬 (30815642)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 28.  澤田 新一郎
    # of Collaborated Projects: 2 results
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  • 29.  Arai Tatsuo (90301275)
    # of Collaborated Projects: 1 results
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  • 30.  ARAI Fumihito (90221051)
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  • 31.  Yamato Masayuki (40267117)
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  • 32.  TAKEUCHI Syouji (90343110)
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  • 33.  SUZUKI Osamu (60374948)
    # of Collaborated Projects: 1 results
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  • 34.  Kaneko Shin (40361331)
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  • 35.  ABURATANI Hiroyuki (10202657)
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  • 77.  IWAHANA Hiroyuki
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  • 78.  IMAI Hiroshi
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  • 85.  GACHELIN Gabriel
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  • 86.  MATSUZAKI Yumi
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  • 87.  GACHELIN Gab
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  • 88.  SANADA Masashi
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  • 89.  Kataoka Keisuke
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  • 90.  Iwabuchi Kazuya
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  • 91.  ETO Tomoo
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  • 94.  CHEN Cheng-hsin
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  • 95.  ASAHINA Yasuhiro
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  • 96.  YAMAGUCHI Tomoyuki
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  • 98.  USUI Joichi
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  • 99.  古関 明彦
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  • 100.  上野 将也
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  • 101.  松井 啓隆
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  • 102.  岩本 由美子
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  • 103.  小林 和人
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  • 104.  狩野 方伸
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  • 105.  服部 浩一
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  • 106.  関 信輔
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  • 107.  HEISSIG Beate
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  • 108.  河原 正浩
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  • 111.  熊野 恵城
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  • 112.  依馬 正次
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  • 113.  高橋 智
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  • 114.  佐藤 雅
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  • 115.  高橋 武司
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  • 116.  伊藤 守
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  • 117.  原田 浩徳
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  • 118.  武藤 誠
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  • 119.  坂本 直哉
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  • 120.  榛葉 繁紀
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    # of Collaborated Products: 1 results
  • 121.  上久保 靖彦
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  • 122.  山本 玲
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  • 123.  森下 和弘
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    # of Collaborated Products: 1 results
  • 124.  小穴 英廣
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    # of Collaborated Products: 1 results
  • 125.  オケヨ ケネディオモンディ
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 126.  鷲津 正夫
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 127.  矢野 文子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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