Michikawa Makoto 道川誠

… Alternative Names

MICHIKAWA Makoto 道川誠

道川誠ミチカワマコト

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Researcher Number	40270912
Other IDs
Affiliation (Current)	2025: 名古屋市立大学, 医薬学総合研究院(医学), 教授
Affiliation (based on the past Project Information) *help	2024 – 2025: 日本歯科大学, 新潟生命歯学部, 教授 2019 – 2023: 名古屋市立大学, 医薬学総合研究院(医学), 教授 2016 – 2018: 名古屋市立大学, 大学院医学研究科, 教授 2016: 名古屋市立大学, 医学研究科, 教授 2015: 名古屋市立大学, 医学部, 教授 … More 2012 – 2015: 名古屋市立大学, 医学(系)研究科(研究院), 教授 2014: 名古屋市立大学, 大学院医学研究科, 教授 2012: 名古屋市立大学, 大学院・医学研究科, 教授 2011: 国立長寿医療センター研究所, アルツハイマー病研究部, 部長 2009 – 2011: National Institute for Longevity Sciences,NCGG, アルツハイマー病研究部, 部長 2008: 国立長寿医療センター(研究所), アルツハイマー研究部, 部長 2007 – 2008: National Institute for Longevity Sciences,NCGG, アルツハイマー病研究部, 部長 2007: 広島大学, 国立長寿医療センター(研究所)・アルツハイマー研究部, 部長 2006: 国立長寿医療センター, (研究所)・アルツハイマー病研究部, 部長 2004: National Institute for Longevity Sciences, Dept.of Alzheimer's Disease Res., Section Chief, 室長 2003: 国立長寿医療研究センター, 室長(研究職) 1999: 国立長寿医療研究センター, 痴呆疾患研究部, 室長 1995 – 1996: 東京医科歯科大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Neurochemistry/Neuropharmacology / Biological Sciences / Basic Section 57050:Prosthodontics-related / Social dentistry / Prosthodontics/ Dental materials science and Except Principal Investigator Basic Section 52010:General internal medicine-related / Neurology / Basic Section 57060:Surgical dentistry-related / Basic Section 57080:Social dentistry-related / Basic Section 51030:Pathophysiologic neuroscience-related … More / Pathobiological dentistry/Dental radiology / Physical pharmacy / Rehabilitation science/Welfare engineering / Neurochemistry/Neuropharmacology / Biofunction/Bioprocess / Prosthodontics/ Dental materials science and / Metabolomics / Prosthetic dentistry / Neurochemistry/Neuropharmacology / Nerve anatomy/Neuropathology / 補綴理工系歯学 / Neurochemistry/Neuropharmacology Less
Keywords	Principal Investigator アルツハイマー病 / 咀嚼機能低下 / 歯牙欠損 / 認知症 / アミロイドベータ蛋白 / アンギオテンシン変換酵素 / 治療 / 蛋白分解酵素 / 精神・神経疾患の病態と治療 / ABCA1 … More / HDL産生 / アポリポ蛋白E / コレステロール / 介入試験 / 認知症進行抑止 / ソフトダイエット / 認知症予防 / 口腔ケア / 歯周病 / 神経細胞死 / 認知機能障害 / 粉末食 / 抜歯 / 鼻閉 / 歯科疾患 / 認知機能 / BDNF / 慢性脳虚血 / レニン・アンギオテンシン / アポリボ蛋白E … More Except Principal Investigator アルツハイマー病 / 認知症 / 動脈硬化 / HDL / 歯の喪失 / アミロイド / アンギオテンシン変換酵素 / アミロイドベータ蛋白 / 神経発生 / サブトラクションcDNAライブラリー / マイクロバイオーム / 加齢 / ストレス / 持続陽圧呼吸療法 / 慢性間欠的低酸素 / 非アルコール性脂肪性肝疾患 / 閉塞性睡眠時無呼吸症 / 16S rRNA菌叢解析 / 脳血管障害 / 血管炎症 / Porphyromonas gingivalis / オーラルディアドコキネシス / オーラルフレイル / 口腔細菌叢 / 口腔機能 / 歯周病 / 腸内フローラ / 認知機能 / 軽度認知障害 / 腸内細菌 / 認知機能障害 / １型糖尿病 / タウタンパク質リン酸化 / タウタンパク質のリン酸化 / ATBF1 / インスリン欠乏 / 糖尿病 / エピジェネティクス / 海馬 / 口腔内病原菌内毒素 / ABCトランスポーター / アミロイドーシス / 脂質異常症 / コレステロール代謝 / ＨＤＬ / 糖鎖 / 脂質膜 / 抗体 / コンフォメーション / アポリポタンパク質 / アポリポ蛋白 / カロリー制限 / 運動 / 予防 / 脳梗塞 / 神経病理 / 鼻粘膜 / 診断 / 脳神経疾患 / neural toxin / amyloid β protein / neural cultured cell / AAMI / docosahexaenoic acid / structured phospholipid / phospholipase D / phosphatidylserine / 神経毒性 / 加齢に伴う記憶力減退 / リパーゼ / ホスフォリパーゼD / 神経毒素 / アミロイドベータタンパク質 / 培養神経細胞 / 老人性記憶力減退 / ドコサヘキサエン酸 / 構造リン脂質 / ホスホリパーゼD / ホスファチジルセリン / NEURAL DEVELOPMENT / THROMOSPONDIN / SUBTRACTION cDNA LIBRARY / MOTORNEURON / 分子生物学 / 遺伝子クローニング / subtraction cDNA library / サブトラクションcDNAライブラリー / トロンボスポンジン / 運動ニューロン / 咬合 / 炎症 / apo E / コレステロール / ファゴサイトーシス / ABCA1 / ABCA7 / 歯・咬合の喪失 / ステップスルー型受動的回避試験 / アミロイドβ / Aβ三変換活性 / 変換酵素 / 精神・神経疾患の病態と治療 / Aβ分解 / インテグリン / プレセニリン / Aβ変換 / アルツハイマー型認知症 / ブレインバンク / タウ / アミロイド蛋白 / タウオパチー / 痴呆 / pCMV発現ベクター / taggingベクター / mutationベクター / 2段階標的遺伝子組換法 / 運動ニューロン単位 / エレクトロポレーション / neural plasticity / PC12 / CMVベクター / pRc / アンドロゲンレセプター / CAGリピート Less

アルツハイマー病の早期診断を可能にする唾液バイオマーカーの開発Principal Investigator
- Principal Investigator
  
  道川誠
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57050:Prosthodontics-related
- Research Institution
  The Nippon Dental University
睡眠時無呼吸症に着目した、脂肪肝と動脈硬化ネットワークの解明とその改善法の提案
- Principal Investigator
  
  廣野玄
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  The Nippon Dental University
加齢における慢性ストレスでの口腔環境の網羅的解析
- Principal Investigator
  
  安彦善裕
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Health Sciences University of Hokkaido
The functional analysis of ATBF1 in the phosphorylation of tau protein
- Principal Investigator
  
  Jung Cha-Gyun
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Nagoya City University
Gerontological investigation of microbiome: a longitudinal estimation study
- Principal Investigator
  
  SAJI NAOKI
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  National Center for Geriatrics and Gerontology
The potential of targeting oral microflora and periodontopathogenic bacteria to prevent dementia.
- Principal Investigator
  
  Matsushita Kenji
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57080:Social dentistry-related
- Research Institution
  National Center for Geriatrics and Gerontology
Genome-wide analysis of epigenetic modification in hippocampus by oral pathogen endotoxin
- Principal Investigator
  
  ABIKO Yoshihiro
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Health Sciences University of Hokkaido
A study to elucidate mechanism, by which periodontists inducing memory impairment and to determine effect of its intervention on progression of dementia.Principal Investigator
- Principal Investigator
  
  Michikawa Makoto
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Social dentistry
- Research Institution
  Nagoya City University
Study on mastication dysfunction-induced memory impairmentPrincipal Investigator
- Principal Investigator
  
  Michikawa Makoto
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Prosthodontics/ Dental materials science and
- Research Institution
  Nagoya City University
Determinations of nasal biomarkers for dementia and development of a novel diagnostic method for Alzheimer's disease using nasal samples.
- Principal Investigator
  
  Tooyama Ikuo
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Shiga University of Medical Science
The effects of pre-conditioning intervention induced alleviating of dysfunction and brain damage after cerebral infarction or dementia.
- Principal Investigator
  
  ISHIDA KAZUTO
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Rehabilitation science/Welfare engineering
- Research Institution
  Nagoya University
ABCA1 and ABCA7: what are their roles in the pathogenesis of Alzheimer's disease?
- Principal Investigator
  
  ABE-DOHMAE Sumiko
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Nagoya City University
The molecular basis of the relationship between Alzheimer's disease and tooth loss
- Principal Investigator
  
  AKAGAWA YASUMASA
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Prosthodontics/ Dental materials science and
- Research Institution
  Ohu University
Physicochemical mechanism on formation and metabolism of HDL particles by apolipoproteins
- Principal Investigator
  
  Saito Hiroyuki
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  Kyoto Pharmaceutical University
  The University of Tokushima
The molecular basis of association mechanism between Alzheimer's disease and tooth loss
- Principal Investigator
  
  AKAGAWA Yasumasa
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Prosthetic dentistry
- Research Institution
  Hiroshima University
Clarification of the molecular mechanism underlying the neuronal death induced by ACE inhibition in APP transgenic mouse
- Principal Investigator
  
  ZOU Kun
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Iwate Medical University
Studies on the role(s) of renin-angiotensin system in the pathogenesis of Alzheimer diseasePrincipal Investigator
- Principal Investigator
  
  MICHIKAWA Makoto
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  National Center for Geriatrics and Gerontology
アルツハイマー病発症機構におけるHDL産生・供給機構の解明と治療への応用Principal Investigator
- Principal Investigator
  
  道川誠
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  National Institute for Longevity Sciences,NCGG
Studies on degradation of amyloid beta-protein by angiotensin-converting enzyme (ACE)Principal Investigator
- Principal Investigator
  
  MICHIKAWA Makoto
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  National Institute for Longevity Sciences,NCGG
アルツハイマー型認知症と歯の喪失・咬合の関連における分子生物学的探求
- Principal Investigator
  
  AKAGAWA Yasumasa
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  補綴理工系歯学
- Research Institution
  Hiroshima University
Angiotensin-converting enzyme as an Aβ-degrading and Aβ42-to-Aβ40-converting enzyme
- Principal Investigator
  
  ZOU Kun
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (Start-up)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Iwate Medical University
脳内コレステロール代謝調節によるアルツハイマー病発症予防・治療に関する研究Principal Investigator
- Principal Investigator
  
  道川誠
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  National Institute for Longevity Sciences,NCGG
Synthesis of Structured Phospholipids Containing Polyunsaturated Fatty Acid and Their Functional Evaluation
- Principal Investigator
  
  YAMANE Tsuneo
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biofunction/Bioprocess
- Research Institution
  Nagoya University
アルツハイマー病発症分子機構に関する総合的研究
- Principal Investigator
  
  森啓
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Osaka City University
Kennedy-Alter-Sung症候群の病態モデルの構築
- Principal Investigator
  
  横田隆徳
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurology
- Research Institution
  Tokyo Medical and Dental University
TRIAL OF SEARCHING FOR MOTORNEURON-SPECIFIC GENES
- Principal Investigator
  
  YAMADA Masahito
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Neurology
- Research Institution
  TOKYO MEDICAL AND DENTAL UNIVERSITY

[Book] 歯科と認知症2015
- Author(s)
  道川　誠、平野浩彦、吉岡裕雄、福井智子、白野美和、須田牧夫
- Total Pages
  110
- Publisher
  メディア出版
- Data Source
  KAKENHI-PROJECT-15K15712
[Book] コレステロール代謝とアルツハイマー病2009
- Author(s)
  道川誠
- Publisher
  シーエムシー出版
- Data Source
  KAKENHI-PROJECT-21300145
[Journal Article] Presenilin 1 deficiency impairs Aβ42-to-Aβ40- and angiotensin-converting activities of ACE.2023
- Author(s)
  Gao Y, Sun Y, Islam S, Nakamura T, Tomita T, Zou K, Michikawa M
- Journal Title
  
  Front Aging Neurosci
  
  Volume: 15 Pages: 1098034-1098034
- DOI
  10.3389/fnagi.2023.1098034
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07352, KAKENHI-PROJECT-19H01015, KAKENHI-PROJECT-20K07861, KAKENHI-PROJECT-23H00394
[Journal Article] Apolipoprotein E4 inhibits γ-secretase activity via binding to the γ-secretase complex2023
- Author(s)
  Sun Y, Islam S, Gao Y, Nakamura T, Zou K, Michikawa M
- Journal Title
  
  J Neurochem
  
  Volume: 164 Issue: 6 Pages: 858-874
- DOI
  10.1111/jnc.15750
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07352, KAKENHI-PROJECT-20K07861
[Journal Article] Accumulation of amyloid-β in the brain of mouse models of Alzheimer's disease is modified by altered gene expression in the presence of human apoE isoforms during aging2023
- Author(s)
  Honda K, Saito Y, Saito H, Toyoda M, Abe R, Saito T, Saido TC, Michikawa M, Taru H, Sobu Y, Hata S, Nakaya T, Suzuki T.
- Journal Title
  
  Neurobiol Aging
  
  Volume: 123 Pages: 63-74
- DOI
  10.1016/j.neurobiolaging.2022.12.003
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07861
[Journal Article] Deletion of UCP1 in Tg2576 Mice Increases Body Temperature and Exacerbates Alzheimer’s Disease-Related Pathologies2023
- Author(s)
  Jung Cha-Gyun、Yamashita Hitoshi、Kato Reiko、Zhou Chunyu、Matsushita Hiroaki、Takeuchi Tamaki、Abdelhamid Mona、Chen Yuxin、Michikawa Makoto
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 24 Issue: 3 Pages: 2741-2741
- DOI
  10.3390/ijms24032741
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07762
[Journal Article] Analysis of the time-dependent changes of phospholipids in the brain regions of a mouse model of Alzheimer’s disease2023
- Author(s)
  Ahsanul Haque Md.、Omori Naoki、Md. Sheikh Abdullah、Yano Shozo、Osago Harumi、Mitaki Shingo、Kalam Azad Abul、Sakai Hiromichi、Michikawa Makoto、Nagai Atsushi
- Journal Title
  
  Brain Research
  
  Volume: 1800 Pages: 148197-148197
- DOI
  10.1016/j.brainres.2022.148197
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07049, KAKENHI-PROJECT-20K07861
[Journal Article] Aβ42 treatment of the brain side reduced the level of flotillin from endothelial cells on the blood side via FGF-2 signaling in a blood-brain barrier model.2023
- Author(s)
  Nakamura T, Hashita T, Chen Y, Gao Y, Sun Y, Islam S, Sato H, Shibuya Y, Zou K, Matsunaga T, Michikawa M
- Journal Title
  
  Mol Brain
  
  Volume: 16 Issue: 1 Pages: 15-15
- DOI
  10.1186/s13041-023-01005-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07352, KAKENHI-PROJECT-20K07861
[Journal Article] Probiotic Bifidobacterium breve prevents memory impairment through the reduction of both Aβ production and microglia activation in APP knock-in mouse.2022
- Author(s)
  Abdelhamid M, Zhou C, Ohno K, Kuhara T, Taslima F, Abdullah M, Jung CG, Michikawa M
- Journal Title
  
  J Alzheimer’s Dis.
  
  Volume: 85(4) Issue: 4 Pages: 1555-1571
- DOI
  10.3233/jad-215025
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07762
[Journal Article] Sustained high body temperature exacerbates cognitive function and Alzheimer’s disease-related pathologies2022
- Author(s)
  Jung Cha-Gyun、Kato Reiko、Zhou Chunyu、Abdelhamid Mona、Shaaban Esraa Ibrahim A.、Yamashita Hitoshi、Michikawa Makoto
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 12273-12273
- DOI
  10.1038/s41598-022-16626-0
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07762, KAKENHI-PROJECT-20K07861
[Journal Article] Presenilin Deficiency Increases Susceptibility to Oxidative Damage in Fibroblasts2022
- Author(s)
  Zou K, Islam S, Sun Y, Gao Y, Nakamura T, Komano H, Tomita T, Michikawa M
- Journal Title
  
  Front Aging Neurosci
  
  Volume: 14 Pages: 902525-902525
- DOI
  10.3389/fnagi.2022.902525
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07352, KAKENHI-PROJECT-20K07861
[Journal Article] Tooth Loss Induces Memory Impairment and Glial Activation in Young Wild-Type Mice2022
- Author(s)
  Taslima Ferdous、Abdelhamid Mona、Zhou Chunyu、Chen Yuxin、Jung Cha-Gyun、Michikawa Makoto
- Journal Title
  
  Journal of Alzheimer's Disease Reports
  
  Volume: 6 Issue: 1 Pages: 663-675
- DOI
  10.3233/adr-220053
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07762, KAKENHI-PROJECT-20K07861
[Journal Article] Probiotic Bifidobacterium breve MCC1274 Mitigates Alzheimer’s Disease-Related Pathologies in Wild-Type Mice2022
- Author(s)
  Abdelhamid Mona、Zhou Chunyu、Jung Cha-Gyun、Michikawa Makoto
- Journal Title
  
  Nutrients
  
  Volume: 14 Issue: 12 Pages: 2543-2543
- DOI
  10.3390/nu14122543
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07762, KAKENHI-PROJECT-20K07861
[Journal Article] Bifidobacterium breve MCC1274 Supplementation Increased the Plasma Levels of Metabolites with Potential Anti-Oxidative Activity in APP Knock-In Mice2022
- Author(s)
  Ohno Kazuya、Abdelhamid Mona、Zhou Chunyu、Jung Cha-Gyun、Michikawa Makoto
- Journal Title
  
  Journal of Alzheimer's Disease
  
  Volume: 89 Issue: 4 Pages: 1413-1425
- DOI
  10.3233/jad-220479
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07762, KAKENHI-PROJECT-20K07861
[Journal Article] Insulin Deficiency Increases Sirt2 Level in Streptozotocin-Treated Alzheimer’s Disease-Like Mouse Model: Increased Sirt2 Induces Tau Phosphorylation Through ERK Activation2022
- Author(s)
  Zhou Chunyu、Jung Cha-Gyun、Kim Mi-Jeong、Watanabe Atsushi、Abdelhamid Mona、Taslima Ferdous、Michikawa Makoto
- Journal Title
  
  Molecular Neurobiology
  
  Volume: 59 Issue: 9 Pages: 5408-5425
- DOI
  10.1007/s12035-022-02918-z
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07762, KAKENHI-PROJECT-20K07861
[Journal Article] Tooth Loss Induces Memory Impairment and Gliosis in App Knock-In Mouse Models of Alzheimer’s Disease2021
- Author(s)
  Taslima Ferdous、Jung Cha-Gyun、Zhou Chunyu、Abdelhamid Mona、Abdullah Mohammad、Goto Tetsuya、Saito Takashi、Saido Takaomi C.、Michikawa Makoto
- Journal Title
  
  Journal of Alzheimer's Disease
  
  Volume: 4 Issue: 4 Pages: 1-18
- DOI
  10.3233/jad-201055
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K17040, KAKENHI-PROJECT-20K07762
[Journal Article] Oral dysfunctions and cognitive impairment/dementia2021
- Author(s)
  Nakamura T, Zou K, Shibuya Y, and Michikawa M
- Journal Title
  
  J Neurosci Res
  
  Volume: 99 Issue: 2 Pages: 518-528
- DOI
  10.1002/jnr.24745
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07861, KAKENHI-PROJECT-19K07846
[Journal Article] A cationic gallium phthalocyanine inhibits amyloid β peptide fibril formation.2020
- Author(s)
  Tabassum S, Sheikh A. M., Yano S, Ikeue T, Mitaki S, Michikawa M and Nagai A
- Journal Title
  
  Curr Alzheimer Res
  
  Volume: 17 Issue: 7 Pages: 1-12
- DOI
  10.2174/1567205017666201008112002
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07861, KAKENHI-PROJECT-18K07369
[Journal Article] Beta-Amyloid Increases the Expression Levels of Tid1 Responsible for Neuronal Cell Death and Amyloid Beta Production.2020
- Author(s)
  Zhou C, Taslima F, Abdelhamid M, Kim SW, Akatsu H, Michikawa M, Jung CG.
- Journal Title
  
  Mol Neurobiol.
  
  Volume: Feb;57(2): Issue: 2 Pages: 1099-1114
- DOI
  10.1007/s12035-019-01807-2
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08725, KAKENHI-PROJECT-20K07861
[Journal Article] High temperature promotes amyloid β-protein production and γ-secretase complex formation via Hsp902020
- Author(s)
  Arshad Ali Noorani, Hitoshi Yamashita, Yuan Gao, Sadequl Islam, Yang Sun, Tomohisa Nakamura, Hiroyuki Enomoto, Kun Zou, Makoto Michikawa
- Journal Title
  
  J Biol Chem
  
  Volume: 295 Issue: 52 Pages: 18010-22
- DOI
  10.1074/jbc.ra120.013845
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07846, KAKENHI-PROJECT-20K06450, KAKENHI-PROJECT-20K07861
[Journal Article] Dietary Lactoferrin Supplementation Prevents Memory Impairment and Reduces Amyloid-beta Generation in J20 Mice2020
- Author(s)
  Abdelhamid, M., Jung, C. G., Zhou, C., Abdullah, M., Nakano, M., Wakabayashi, H., Abe, F., Michikawa M
- Journal Title
  
  J Alzheimers Dis
  
  Volume: 74 Issue: 1 Pages: 245-259
- DOI
  10.3233/jad-191181
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07861, KAKENHI-PROJECT-19K17040
[Journal Article] Current Biomarkers for Alzheimer's Disease: From CSF to Blood2020
- Author(s)
  Kun Zou, Mohammad Abdullah, Makoto Michikawa
- Journal Title
  
  J Pers Med
  
  Volume: 10 Issue: 3 Pages: 85-85
- DOI
  10.3390/jpm10030085
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07846, KAKENHI-PROJECT-20K07861, KAKENHI-PROJECT-19K17040
[Journal Article] Neurodegeneration of trigeminal mesencephalic neurons by the tooth loss triggers the progression of Alzheimer's disease in 3xTg-AD model mice.2020
- Author(s)
  Goto T, Kuramoto E, Dhar A, Wang RP-H, Seki H, Iwai H, Yamanaka A, Matsumoto S, Hara H, Michikawa M, Ohyagi Y, Leung WK, Chang RC-C
- Journal Title
  
  Journal of Alzheimer's Disease
  
  Volume: 76 Issue: 4 Pages: 1443-1459
- DOI
  10.3233/jad-200257
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07826, KAKENHI-PROJECT-20K07861, KAKENHI-PROJECT-20K10296, KAKENHI-PLANNED-17H06311
[Journal Article] Nasal obstruction during adolescence induces memory/learning impairments associated with BDNF/TrkB signaling pathway hypofunction and high corticosterone levels2018
- Author(s)
  Ogawa Takuya、Okihara Hidemasa、Kokai Satoshi、Abe Yasunori、Karin Harumi Uchima Koecklin、Makiguchi Mio、Kato Chiho、Yabushita Tadachika、Michikawa Makoto、Ono Takashi
- Journal Title
  
  Journal of Neuroscience Research
  
  Volume: 96 Issue: 6 Pages: 1056-1065
- DOI
  10.1002/jnr.24216
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K11338, KAKENHI-PROJECT-15K11339, KAKENHI-PROJECT-15K15712, KAKENHI-PROJECT-16H05559, KAKENHI-PROJECT-15K20581
[Journal Article] Tau Depletion in APP Transgenic Mice Attenuates Task-Related Hyperactivation of the Hippocampus and Differentially Influences Locomotor Activity and Spatial Memory2018
- Author(s)
  Yoshikawa Misato、Soeda Yoshiyuki、Michikawa Makoto、Almeida Osborne F. X.、Takashima Akihiko
- Journal Title
  
  Frontiers in Neuroscience
  
  Volume: 12 Pages: 124-124
- DOI
  10.3389/fnins.2018.00124
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15712, KAKENHI-PLANNED-26117004, KAKENHI-PROJECT-16H05559
[Journal Article] Defensive effect of microRNA-200b/c against amyloid-beta peptide-induced toxicity in Alzheimer's disease models2018
- Author(s)
  Higaki Sayuri、Muramatsu Masashi、Matsuda Akio、Matsumoto Kenji、Satoh Jun-ichi、Michikawa Makoto、Niida Shumpei
- Journal Title
  
  PLOS ONE
  
  Volume: 13 Issue: 5 Pages: e0196929-e0196929
- DOI
  10.1371/journal.pone.0196929
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05559, KAKENHI-PROJECT-16K07043, KAKENHI-PROJECT-17K15622, KAKENHI-PROJECT-17K10166
[Journal Article] Deficiency of a sulfotransferase for sialic acid-modified glycans mitigates Alzheimer's pathology.2017
- Author(s)
  Zhang Z, Takeda-Uchimura Y, Foyez T, Ohtake-Niimi S, Narentuya, Akatsu H, Nishitsuji K, Michikawa M, Wyss-Coray T, Kadomatsu K, Uchimura K.
- Journal Title
  
  Proc Natl Acad Sci U S A.
  
  Volume: 114(14) Issue: 14 Pages: 114-114
- DOI
  10.1073/pnas.1615036114
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-WRAPUP-16H01694, KAKENHI-PROJECT-16H05559, KAKENHI-PROJECT-15K15079, KAKENHI-PROJECT-17K16123, KAKENHI-PROJECT-16H05139, KAKENHI-PROJECT-15K15712, KAKENHI-PROJECT-16H06277
[Journal Article] Periodontitis induced by bacterial infection exacerbates features of Alzheimer's disease in transgenic mice2017
- Author(s)
  Ishida N, Ishihara Y, Ishida K, Tada H, Funaki-Kato Y, Hagiwara M, Ferdous T, Abdullah M, Mitani A, Michikawa M, Matsushita K.
- Journal Title
  
  NPJ Aging Mech. Dis.
  
  Volume: 3 Issue: 1 Pages: 15-15
- DOI
  10.1038/s41514-017-0015-x
- NAID
  120006576159
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11824, KAKENHI-PROJECT-16K11845, KAKENHI-PROJECT-17K17362, KAKENHI-PROJECT-26293438, KAKENHI-PROJECT-15K11402, KAKENHI-PROJECT-15K15712, KAKENHI-PROJECT-26861586, KAKENHI-PROJECT-16H05559
[Journal Article] Sodium balance, circadian BP rhythm, heart rate variability, and intrarenal renin-angiotensin-aldosterone and dopaminergic systems in acute phase of ARB therapy2017
- Author(s)
  Isobe-Sasaki Yukako、Fukuda Michio、Ogiyama Yoshiaki、Sato Ryo、Miura Toshiyuki、Fuwa Daisuke、Mizuno Masashi、Matsuoka Tetsuhei、Shibata Hiroko、Ito Hiroyuki、Ono Minamo、Abe-Dohmae Sumiko、Kiyono Ken、Yamamoto Yoshiharu、Kobori Hiroyuki、Michikawa Makoto、Hayano Junichiro、Ohte Nobuyuki
- Journal Title
  
  Physiological Reports
  
  Volume: 5 Issue: 11 Pages: e13309-e13309
- DOI
  10.14814/phy2.13309
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H00878, KAKENHI-PROJECT-15K12678, KAKENHI-PROJECT-15K15712, KAKENHI-PROJECT-16H05559
[Journal Article] Addition of hydrochlorothiazide to angiotensin receptor blocker therapy can achieve a lower sodium balance with no acceleration of intrarenal renin angiotensin system in patients with chronic kidney disease.2016
- Author(s)
  Fuwa D, Fukuda M, Ogiyama Y, Sato R, Mizuno M, Miura T, Abe-Dohmae S, Michikawa M, Kobori H, Ohte N.
- Journal Title
  
  J Renin Angiotensin Aldosterone Syst.
  
  Volume: 17 Issue: 2
- DOI
  10.1177/1470320316652032
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25461375
[Journal Article] Phosphatidylcholine protects neurons from toxic effects of amyloid beta-protein in culture.2016
- Author(s)
  Ko M, Hattori T, Abdullah M, Gong JS, Yamane T, Michikawa M.
- Journal Title
  
  Brain Res
  
  Volume: 1642 Pages: 376-383
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05559
[Journal Article] Aβ reduces exosome release from astrocytes by enhancing JNK phosphorylation2016
- Author(s)
  Abdullah M, Takase H, Nunome M, Enomoto H, Ito J-I, Gong J-S, and Michikawa M.
- Journal Title
  
  J Alzhiemr Dis,
  
  Volume: 53 Issue: 4 Pages: 1433-1441
- DOI
  10.3233/jad-160292
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05559, KAKENHI-PROJECT-25461375, KAKENHI-PROJECT-15K15712
[Journal Article] ABCG1 and ABCG4 Suppress γ-Secretase Activity and Amyloid β Production2016
- Author(s)
  Osamu Sano, Maki Tsujita, Yuuji Shimizu, Reiko Kato, Aya Kobayashi, Noriyuki Kioka, Alan T Remaley, Makoto Michikawa, Kazumitsu Ueda, and Michinori Matsuo
- Journal Title
  
  PLoS One
  
  Volume: 11 Issue: 5 Pages: e0155400-e0155400
- DOI
  10.1371/journal.pone.0155400
- NAID
  120005997762
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25221203, KAKENHI-PROJECT-16H05559, KAKENHI-PROJECT-25461375, KAKENHI-PROJECT-15K15349, KAKENHI-PROJECT-15K15712, KAKENHI-PROJECT-16K15090
[Journal Article] Molar loss and powder diet leads to memory deficit and modifies the mRNA expression of brain-derived neurotrophic factor in the hippocampus of adult mice.2016
- Author(s)
  Takeda Y, Oue H, Okada S, Kawano A, Koretake K, Michikawa M, Akagawa Y, Tsuga K.
- Journal Title
  
  BMC Neurosci.
  
  Volume: ５ Issue: 1 Pages: 81-81
- DOI
  10.1186/s12868-016-0319-y
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16K20501, KAKENHI-PROJECT-15K15712
[Journal Article] Phosphatidylcholine protects neurons from toxic effects of amyloid β-protein in culture.2016
- Author(s)
  Ko M, Hattori T, Abdullah M, Gong JS, Yamane T, Michikawa M.
- Journal Title
  
  Brain Res.
  
  Volume: 1642 Pages: 376-383
- DOI
  10.1016/j.brainres.2016.04.035
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461375, KAKENHI-PROJECT-15K15712
[Journal Article] Effect of overexpression of lipoprotein lipase (LPL) on Ab burden and memory function in LPL and APP double-transgenic mice2016
- Author(s)
  Mari Nunome, Hiroyuki Enomoto, Mohammad Abdullah, Kazuto Ishida, Jian-Sheng Gong, Cha-Gyun Jung, Michihiro Kamijima, Makoto Michikawa
- Journal Title
  
  Journal of Systems and Integrative Neuroscience
  
  Volume: ２ Issue: 4 Pages: 213-218
- DOI
  10.15761/jsin.1000138
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26350610
[Journal Article] Arachidonic Acid Diet Attenuates Aβ Deposition in Tg2576 Mice.2015
- Author(s)
  Hosono T, Nishitsuji K, Nakamura T, Jung CG, Kontani M, Tokuda H, Kawashima H, Kiso Y, Suzuki T, Michikawa M
- Journal Title
  
  Brain Res
  
  Volume: 10 Pages: 1613-1629
- DOI
  10.1016/j.brainres.2015.04.005
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06714, KAKENHI-PROJECT-25461375, KAKENHI-PROJECT-15K15712, KAKENHI-PROJECT-15K19488, KAKENHI-PROJECT-26293010
[Journal Article] Tooth loss might not alter molecular pathogenesis in an aged transgenic Alzheimer's disease model mouse2015
- Author(s)
  Oue H, Miyamoto Y, Koretake K, Okada S, Doi K, Jung CG, Michikawa M and Akagawa Y
- Journal Title
  
  Gerodontology
  
  Volume: in press Issue: 3 Pages: 308-14
- DOI
  10.1111/ger.12153
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24500402, KAKENHI-PROJECT-25670820, KAKENHI-PROJECT-16H05559, KAKENHI-PROJECT-15K15712
[Journal Article] ATBF1 is a novel amyloid-β protein precursor protein (AβPP) binding protein that affects APP expression2015
- Author(s)
  Uhm KO, Kim MJ, Kawaguchi M, Akatsu H, Miura Y, Misumi S, Hida H, Choi EK, Kim YS, Michikawa M, Jung CG.
- Journal Title
  
  J Alzheimers Dis
  
  Volume: 43 Issue: 1 Pages: 243-257
- DOI
  10.3233/jad-140612
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24500402, KAKENHI-PROJECT-15K06714, KAKENHI-PROJECT-25461375, KAKENHI-PROJECT-15K15712
[Journal Article] Biochemical properties in membrane of rat astrocytes under oxidative stress.2015
- Author(s)
  Ito J, Nagayasu Y, Ogawa T, Okihara H, Michikawa M.
- Journal Title
  
  Brain Res.
  
  Volume: 1615 Pages: 1-11
- DOI
  10.1016/j.brainres.2015.04.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461375, KAKENHI-PROJECT-15K15712
[Journal Article] Auraptene increases the production of amyloid-beta via c-Jun N-terminal kinase-dependent activation of γ-secretase.2015
- Author(s)
  Jung CG, Uhm KO, Horike H, Kim MJ, Misumi S, Ishida A, Ued Y, Choi EK, Kim YS, Michikawa M, Hida H.
- Journal Title
  
  J Alzheimers Dis
  
  Volume: 43 Issue: 4 Pages: 1215-1228
- DOI
  10.3233/jad-141692
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24500402, KAKENHI-PROJECT-15K06714, KAKENHI-PROJECT-25461375, KAKENHI-PROJECT-15K15712
[Journal Article] Arachidonic or docosahexaenoic acid diet prevents memory impairment in Tg2576 mice.2015
- Author(s)
  Hosono T, Mouri A, Nishitsuji K, Jung CG, Kontani M, Tokuda H, Kawashima H, Shibata H, Suzuki T, Nabeshima T, Michikawa M.
- Journal Title
  
  J Alzheimers Dis
  
  Volume: 48 Issue: 1 Pages: 149-162
- DOI
  10.3233/jad-150341
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06714, KAKENHI-PROJECT-25461375, KAKENHI-PROJECT-26460240, KAKENHI-PROJECT-15K15712, KAKENHI-PROJECT-15K19488, KAKENHI-PROJECT-26293010
[Journal Article] Lysophosphatidylcholine increases the neurotoxicity of Alzheimer's amyloid β1-42 peptide: role of oligomer formation.2015
- Author(s)
  Sheikh AM, Michikawa M, Kim SU, Nagai A.
- Journal Title
  
  Neuroscience.
  
  Volume: 292 Pages: 159-69
- DOI
  10.1016/j.neuroscience.2015.02.034
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461375, KAKENHI-PROJECT-15K15712
[Journal Article] Angiotensin type 1a receptor deficiency decreases amyloid β-protein generation and ameliorates brain amyloid pathology.2015
- Author(s)
  Liu J, Liu S, Matsumoto Y, Murakami S, Sugakawa Y, Kami A, Tanabe C, Maeda T, Michikawa M, Komano H, Zou K.
- Journal Title
  
  Sci Rep.
  
  Volume: 5 Issue: 1 Pages: 12059-12059
- DOI
  10.1038/srep12059
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25461375, KAKENHI-PROJECT-26430057, KAKENHI-PROJECT-15K15712
[Journal Article] Increasing Cellular Level of Phosphatidic Acid Enhances FGF-1 Production in Long Term-cultured Rat Astrocytes2014
- Author(s)
  Yuko Nagayasu, Shin-ya Morita, Hideki Hayashi, Yutaka Miura, Kazuki Yokoyama, Makoto Michikawa, Jin-ichi Ito
- Journal Title
  
  Brain Research
  
  Volume: 1563 Pages: 31-40
- DOI
  10.1016/j.brainres.2014.03.035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24500441, KAKENHI-PROJECT-25461375
[Journal Article] Involvement of cdc42/Rho kinase in apoA-I-mediated cholesterol efflux through interaction between cytosolic lipid-protein particles and microtubules in rat astrocytes.2014
- Author(s)
  11. Kheirollah A., Nagayasu Y., Ueda H., Yokoyama S. Michikawa M. and Ito J.
- Journal Title
  
  J. Neurosci. Res.
  
  Volume: 92 Issue: 4 Pages: 455-463
- DOI
  10.1002/jnr.23324
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590073, KAKENHI-PROJECT-24614018, KAKENHI-PROJECT-25461375
[Journal Article] Astrocytes endogenous apoE generates HDL-like lipoproteins using previously synthesized cholesterol through interaction with ABCA12014
- Author(s)
  Ito, J. Nagayasu, Y. Miura, Y. Yokoyama, S. Michikawa, M.
- Journal Title
  
  Brain Res
  
  Volume: 1570 Pages: 1-12
- DOI
  10.1016/j.brainres.2014.04.037
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461375
[Journal Article] KSGal6ST is essential for the 6-sulfation of galactose within keratan sulfate in early postnatal brain.2014
- Author(s)
  Hoshino H, Foyez T, Ohtake-Niimi S, Takeda-Uchimura Y, Michikawa M, Kadomatsu K, Uchimura K.
- Journal Title
  
  J Histochem Cytochem.
  
  Volume: 62 Issue: 2 Pages: 145-156
- DOI
  10.1369/0022155413511619
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-ORGANIZER-23110001, KAKENHI-PLANNED-23110002, KAKENHI-PROJECT-24590349, KAKENHI-PROJECT-25461375
[Journal Article] Liquid diet induces memory impairment accompanied by a decreased number of hippocampal neurons in mice.2014
- Author(s)
  Okihara H, Ito J, Kokai S, Ishida T, Hiranuma M, Kato C, Yabushita T, Ishida K, Ono T, Michikawa M.
- Journal Title
  
  J Neurosci Res.
  
  Volume: 92 Issue: 8 Pages: 1010-7
- DOI
  10.1002/jnr.23383
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24593081, KAKENHI-PROJECT-24792279, KAKENHI-PROJECT-25461375, KAKENHI-PROJECT-26350610
[Journal Article] Aβ43 is the earliest depositing Aβ species in APP transgenic mouse brain and is converted to Aβ41 by two active domains of ACE.2013
- Author(s)
  Zou K, Liu J, Watanabe A, Hiraga S, Liu S, Tanabe C, Maeda T, Terayama Y, Takahashi S, Michikawa M, Komano H
- Journal Title
  
  Am J Pathol
  
  Volume: 182 Issue: 6 Pages: 2311-2331
- DOI
  10.1016/j.ajpath.2013.01.053
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24700383, KAKENHI-PROJECT-25461375
[Journal Article] Tooth loss induces memory impairment and neuronal cell loss in APP transgenic mice.2013
- Author(s)
  Oue H, Miyamoto Y, Okada S, Koretake K, Jung CG, Michikawa M, Akagawa Y.
- Journal Title
  
  Behav Brain Res.
  
  Volume: 252(1) Pages: 318-325
- DOI
  10.1016/j.bbr.2013.06.015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24500402, KAKENHI-PROJECT-25461375
[Journal Article] Enhancement of FGF-1 release along with cytosolic proteins from rat astrocytes by hydrogen peroxide.2013
- Author(s)
  Ito J, Nagayasu Y, Hoshikawa M, Kato KH, Miura Y, Asai K, Hayashi H, Yokoyama S, Michikawa M.
- Journal Title
  
  Brain Res.
  
  Volume: 1522 Pages: 12-21
- DOI
  10.1016/j.brainres.2013.05.035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591509, KAKENHI-PROJECT-24614018, KAKENHI-PROJECT-25461375
[Journal Article] Heparan Sulfate Subdomains that are Degraded by Sulf Accumulate in Cerebral Amyloid s Plaques of Alzheimer's Disease : Evidence from Mouse Models and Patients2012
- Author(s)
  Hosono-Fukao T, Ohtake-Niimi S, Hoshino H, Akatsu H, Hossain M, Nishitsuji K, van Kuppevelt, Kimata K, Michikawa M, Wyss-Coray T, Uchimura K.
- Journal Title
  
  Am J Pathol
  
  Volume: 180(5) Pages: 2056-2067
- Data Source
  KAKENHI-PROJECT-21300145
[Journal Article] Beta-amyloid increases the expression level of ATBF1 responsible for death in cultured cortical neurons2011
- Author(s)
  Jung C-G, Uhm K-O, Miura Y, Hosono T, Horike H, Khanna K K, Michikawa M
- Journal Title
  
  Mol Neurodegener
  
  Volume: 6 Pages: 47-58
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300145
[Journal Article] Higher activity of peripheral blood angiotensin-converting enzyme is associated with later-onset of Alzheimer's disease.2011
- Author(s)
  Akatsu H, Ogawa N, Kanesaka T, Hori A, Yamamoto T, Matsukawa N, Michikawa M
- Journal Title
  
  J.Neurol.Sci.
  
  Volume: 300 Pages: 67-73
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300145
[Journal Article] Association between cognitive function and plasma lipids of the elderly after controlling for apolipoprotein E genotype.2011
- Author(s)
  Yasuno F, Tanimukai S, Sasaki M, Hidaka S, Ikejima C, Yamashita F, Kodama C, Mizukami K, Michikawa M, Asada T.
- Journal Title
  
  Am.J.Geriat.Psychiat.
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300145
[Journal Article] ER-stress-inducible Herp, facilitates the degradation of immature nicastrin2011
- Author(s)
  Toshihiro Marutani, Tomoji Maeda, Chiaki Tanabe, Kun Zou, Wataru Araki, Koichi Kokame, Makoto Michikawa, Hiroto Komano
- Journal Title
  
  Biochimica et Biophysica Acta
  
  Volume: 1810 Pages: 790-798
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22700399
[Journal Article] ER-stress-indudcile Herp, facilitates the degradation of immature nicastrin2011
- Author(s)
  Marutani T, Maeda T, Tanabe C, Zou K, Araki W, Kokame K, Michikawa M, Komano H
- Journal Title
  
  Biochim.Biophys.Acta
  
  Volume: 1810 Pages: 790-798
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300145
[Journal Article] Extracellular and intraneuronal HMW-Aβ oligomers represent a molecular basis of memory loss in Alzheimer'sdisease model mouse.2011
- Author(s)
  Takamura A, Okamoto Y, Kawarabayashi T, Yokoseki T, Shibata M, Mouri A, Nabeshima T, Sun H, Abe K, Shoji M, Yanagisawa K, Michikawa M, Matsubara E.
- Journal Title
  
  Mol.Neurodegener.
  
  Volume: 6:20 Pages: 1-16
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300145
[Journal Article] Extracellular and intraneuronal HMW-Aβoligomers represent a molecular basis of memory loss in Alzheimer's disease model mouse2011
- Author(s)
  Takamura A, Okamoto Y, Kawarabayashi T, Yokoseki T, Shibata M, Mouri A, Nabeshima T, Sun H, Abe K, Shoji M, Yanagisawa K, Michikawa M, Matsubara E.
- Journal Title
  
  Mol. Neurodegener
  
  Volume: 6 Pages: 20-20
- Data Source
  KAKENHI-PROJECT-21300145
[Journal Article] ER-stress-inducible Herp, facilitates the degradation of immature nicastrin2011
- Author(s)
  Marutani T, Maeda T, Tanabe C, Zou K, Araki W, Kokame K, Michikawa M and Komano H
- Journal Title
  
  Biochim. Biophys. Acta
  
  Volume: 1810 Pages: 790-798
- Data Source
  KAKENHI-PROJECT-22700399
[Journal Article] RB4CD12 epitope expression and heparan sulfate disaccharide composition in brain vasculature2011
- Author(s)
  Hosono-Fukao T, Ohtake-Niimi S, Nishitsuji K, Hossain M, van Kuppevelt TH, Michikawa M, Uchimura K
- Journal Title
  
  J.Neurosd.Res.
  
  Volume: 89 Pages: 1840-1848
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300145
[Journal Article] Lipoprotein lipase is a novel Aβ-binding protein that promotes glycosaminoglycan-dependent cellular uptake of Aβin astrocytes2011
- Author(s)
  Nishitsuji K, Hosono T, Uchimura K, Michikawa M.
- Journal Title
  
  J. Biol. Chem
  
  Volume: 286 Pages: 6393-6401
- Data Source
  KAKENHI-PROJECT-21300145
[Journal Article] The dissociation of Aβ from lipoprotein in cerebrospinal fluid from Alzheimer's disease accelerates Aβ42 assembly.2011
- Author(s)
  Takamura A, Kawarabayashi T, Yokoseki T, Shibata M, Morishima-Kawashima M, Saito Y, Murayama S, Ihara Y, Abe K, Shoji M, Michikawa M, Matsubara E.
- Journal Title
  
  J.Neurosci.Res.
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300145
[Journal Article] ER-stress-inducible Herp, facilitates the degradation f immature nicastrin2011
- Author(s)
  Marutani T, Maeda T, Tanabe C, Zou K, Araki W, Kokame K, Michikawa M, Komano H.
- Journal Title
  
  Biochim. Biophys. Acta
  
  Volume: 1810 Pages: 790-8
- Data Source
  KAKENHI-PROJECT-21300145
[Journal Article] Extracellular and intraneuronal HMW-Aβ oligomers represent a molecular basis of memory loss in Alzheimer's disease model mouse2011
- Author(s)
  Takamura A, Okamoto Y, Kawarabayashi T, Yokoseki T, Shibata M, Mouri A, Nabeshima T, Sun H, Abe K, Shoji M, Yanagisawa K, Michikawa M, Matsubara E
- Journal Title
  
  Mol.Neurodegener.
  
  Volume: 6 Pages: 20-35
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300145
[Journal Article] Lipoprotein lipase is a novel Aβ-binding protein that promotes glycosaminoglycan-dependent cellular uptake of Aβ in astrocytes2011
- Author(s)
  Nishitsuji K, Hosono T, Uchimura K, Michikawa M
- Journal Title
  
  J.Biol.Chem
  
  Volume: 286 Issue: 8 Pages: 6393-6401
- DOI
  10.1074/jbc.m110.172106
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300145
[Journal Article] Higher activity of peripheral blood angiotensin-converting enzyme is associated with later-onset of Alzheimer's disease2011
- Author(s)
  Akatsu H, Ogawa N, Kanesaka T, Hori A, Yamamoto T, Matsukawa N, Michikawa M
- Journal Title
  
  J.Neurol.Sci
  
  Volume: 300 Issue: 1-2 Pages: 67-73
- DOI
  10.1016/j.jns.2010.09.030
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300145
[Journal Article] The dissociation of Aβ from lipoprotein in cerebrospinal fluid from Alzheimer's disease accelerates Aβ42 assembly2011
- Author(s)
  Takamura A, Kawarabayashi T, Yokoseki T, Shibata M, Morishima-Kawashima M, Saito Y, Murayama S, Ihara Y, Abe K, Shoji M, Michikawa M, Matsubara E
- Journal Title
  
  J.Neurosci.Res.
  
  Volume: 6 Pages: 815-821
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300145
[Journal Article] Association between cognitive function and plasma lipids of the elderly after controlling for apolipoprotein E genotype2011
- Author(s)
  Yasuno F, Tanimukai S, Sasaki M, Hidaka S, Ikejima C, Yamashita F, Kodama C, Mizukami K, Michikawa M, Asada T
- Journal Title
  
  Am.J.Geriat.Psychiat
  
  Volume: (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300145
[Journal Article] The dissociation of Aβfrom lipoprotein in cerebrospinal fluid from Alzheimer's disease accelerates Aβ42 assembly2011
- Author(s)
  Takamura A, Kawarabayashi T, Yokoseki T, Shibata M, Morishima-Kawashima M, Saito Y, Murayama S, Ihara Y, Abe K, Shoji M, Michikawa M, Matsubara E.
- Journal Title
  
  J. Neurosci. Res
  
  Volume: 6 Pages: 815-821
- Data Source
  KAKENHI-PROJECT-21300145
[Journal Article] RB4CD12 epitope expression and heparan sulfate disaccharide composition in brain vasculature.2011
- Author(s)
  Hosono-Fukao T, Ohtake-Niimi S, Nishitsuji K, Hossain M, van Kuppevelt TH, Michikawa M, Uchimura K.
- Journal Title
  
  J. Neurosci. Res
  
  Volume: 89 Pages: 1840-8
- Data Source
  KAKENHI-PROJECT-21300145
[Journal Article] Apolipoprotein E regulates the integrity of tight junctions in an isoform-dependent manner in an in vitro blood-brain-barrier model2011
- Author(s)
  Nishitsuji K, Hosono T, Nakamura T, Bu G, Michikawa M
- Journal Title
  
  J.Biol.Chem
  
  Volume: 286 Issue: 20 Pages: 17536-17542
- DOI
  10.1074/jbc.m111.225532
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300145
[Journal Article] Apolipoprotein E regulates the integrity of tight junctions in an isoform-dependent manner in an in vitro blood-brain-barrier model2011
- Author(s)
  Nishitsuji K, Hosono T, Nakamura T, Bu G, Michikawa M.
- Journal Title
  
  Biol. Chem
  
  Volume: 286(20) Pages: 17536-17542
- Data Source
  KAKENHI-PROJECT-21300145
[Journal Article] Higher activity of peripheral blood angiotensin-converting enzyme is associated with later-onset of Alzheimer's disease.2011
- Author(s)
  Akatsu H, Ogawa N, Kanesaka T, Hori A, Yamamoto T, Matsukawa N, Michikawa M.
- Journal Title
  
  J. Neurol. Sci
  
  Volume: 300 Pages: 67-73
- Data Source
  KAKENHI-PROJECT-21300145
[Journal Article] Beta-amyloid increases the expression level of ATBF1 responsible for death in cultured cortical neurons2011
- Author(s)
  Jung C-G, Uhm K-O, Miura Y, Hosono T, Horike H, Khanna K K, Michikawa M.
- Journal Title
  
  Mol Neurodegener
  
  Volume: 6 Pages: 47-47
- Data Source
  KAKENHI-PROJECT-21300145
[Journal Article] Lipoprotein lipase is a novel Aβ-binding protein that promotes glycosaminoglycan-dependent cellular uptake of Aβ in astrocytes.2011
- Author(s)
  Nishitsuji K, Hosono T, Uchimura K, Michikawa M.
- Journal Title
  
  J.Biol.Chem.
  
  Volume: 286 Pages: 6393-6401
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300145
[Journal Article] Honokiol increases ABCA1 expression level by activating retinoid X receptor β.2010
- Author(s)
  Jung C-G, Horike H, Cha B-Y, Uhm K-O, Yamauchi R, Yamaguchi T, Hosono T, Iida K, Woo J-T, Michikawa M.
- Journal Title
  
  Biol.Pharm.Bull
  
  Volume: 33 Pages: 1105-1111
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300145
[Journal Article] A novel Aβ-converting activity of angiotensin-converting enzyme and its role in Alzheimer's disease2010
- Author(s)
  Zou K., Michikawa M. and Komano H
- Journal Title
  
  Seikagaku
  
  Volume: 82 Pages: 1120-1124
- NAID
  10027880213
- Data Source
  KAKENHI-PROJECT-22700399
[Journal Article] Honokiol increases ABCA1 expression level by activating retinoid X receptorβ2010
- Author(s)
  Jung C-G, Horike H, Cha B-Y, Uhm K-O, Yamauchi R, Yamaguchi T, Hosono T, Iida K, Woo J-T, Michikawa M
- Journal Title
  
  Biol. Pharm. Bull
  
  Volume: 33 Pages: 1105-1111
- Data Source
  KAKENHI-PROJECT-21300145
[Journal Article] 脳のレニンアンギオテンシン系とアミロイドβ蛋白質代謝2010
- Author(s)
  道川誠
- Journal Title
  
  Dementia Japan
  
  Volume: 24巻 Pages: 419-423
- Data Source
  KAKENHI-PROJECT-21300145
[Journal Article] アンギオテンシン変換酵素の新しい顔:Aβ変換酵素2010
- Author(s)
  ゾウクン、道川誠、駒野宏人
- Journal Title
  
  生化学
  
  Volume: 82巻 Pages: 1120-1124
- NAID
  10027880213
- Data Source
  KAKENHI-PROJECT-21300145
[Journal Article] アンギオテンシン変換酵素の新しい顔:Aβ変換酵素2010
- Author(s)
  鄒鶤、道川誠、駒野宏人
- Journal Title
  
  生化学
  
  Volume: 第八十二巻 Pages: 1120-1124
- NAID
  10027880213
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22700399
[Journal Article] Homocysteine, another risk factor for Alzheimer's disease, impairs apolipoprotein E3 function.2010
- Author(s)
  Minagawa H, Watanabe A, Akatsu H, Adachi K, Ohtsuka C, Terayama Y, Hosono T, Takahashi S, Wakita H, Jung C-G, Komano H, Michikawa M.
- Journal Title
  
  J.Biol.Chem.
  
  Volume: 285 Pages: 38382-38388
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300145
[Journal Article] アポリポ蛋白Eとアルツハイマー病2010
- Author(s)
  道川誠
- Journal Title
  
  Clinical Neuroscience
  
  Volume: 28巻 Pages: 992-995
- Data Source
  KAKENHI-PROJECT-21300145
[Journal Article] Homocysteine, another risk factor for Alzheimer's disease, impairs apolipoprotein E3 function2010
- Author(s)
  Minagawa H, Watanabe A, Akatsu H, Adachi K, Ohtsuka C, Terayama Y, Hosono T, Takahashi S, Wakita H, Jung C-G, Komano H, Michikawa M.
- Journal Title
  
  J. Biol. Chem
  
  Volume: 285 Pages: 38382-38388
- Data Source
  KAKENHI-PROJECT-21300145
[Journal Article] アルツハイマー病分子病態とアポリポ蛋白E2010
- Author(s)
  道川誠
- Journal Title
  
  医療の広場
  
  Volume: 50巻 Pages: 4-5
- NAID
  40018890647
- Data Source
  KAKENHI-PROJECT-21300145
[Journal Article] Bioactive TGF-βcan associate with lipoproteins and is enriched in those containing apolipoprotein E32009
- Author(s)
  Tesseur I, Brecht W, Corn J, Gong J-S, Yanagisawa K, Michikawa M, Weisgraber K, Huang Y, and Wyss-Coray T.
- Journal Title
  
  J. Neurochem
  
  Volume: 110(4) Pages: 1254-1262
- Data Source
  KAKENHI-PROJECT-21300145
[Journal Article] An E3 ubiquitin ligase, Synoviolin is involved in the degradation of immature Nicastrin, and regulates the production of amyloid b-protein.2009
- Author(s)
  Maeda T, Marutani T, Zou K, Araki W, Yagishita N, Yamamoto Y, Amano T, Michikawa M, Nakajima T, Komano H.
- Journal Title
  
  FEBS J 276
  
  Pages: 5832-58401
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300145
[Journal Article] Mechanism underlying apolipoprotein E isoform-dependent lipid efflux from neural cells in culture.2009
- Author(s)
  Minagawa K, Gong J-S, Jung C-G, Watanabe A. Lund-Katz S, Phillips M C, Saito H, Michikawa M.
- Journal Title
  
  J.Neurosci.Res 87
  
  Pages: 2498-2508
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20023040
[Journal Article] Angiotensin-converting enzyme as a potential target for treatment of Alzheimer's disease : Inhibition or activation?2009
- Author(s)
  Zou K and Michikawa M
- Journal Title
  
  Rev Neurosci, 19
  
  Pages: 203-212
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20023040
[Journal Article] Angiotensin-converting enzyme as a potential target for treatment of Alzheimer's disease : Inhibition or activation?2009
- Author(s)
  Zou K, Michikawa M
- Journal Title
  
  Rev Neurosci, 19
  
  Pages: 203-212
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300138
[Journal Article] Aβ42-to-Aβ40- and angiotensin- converting activities in different domain of angiotensin-converting enzyme2009
- Author(s)
  Zou K, Maeda T, Oba R, Komano H, Michikawa M
- Journal Title
  
  J.Biol.Chem. 284
  
  Pages: 31914-31920
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300145
[Journal Article] Microglia activated with toll-like receptor 9 ligand CpG attenuate oligomeric amyloid-β neurotoxicity in vitro and invivo models of Alzheimer's disease.2009
- Author(s)
  Doi Y, Mizuno T, Maki Y, Jin S, Mizoguchi H, Ikeyama M, Doi M, Michikawa M, Takeuchi H, Suzumura A
- Journal Title
  
  Am.J.Pathol. 175
  
  Pages: 2121-2132
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300145
[Journal Article] Bioactive TGF-β can associate with lipoproteins and is enriched in those containing apolipoprotein E32009
- Author(s)
  Tesseur I, Brecht W, Corn J, Gong J-S, Yanagisawa K, Michikawa M, Weisgraber K, Huang Y, Wyss-Coray T.
- Journal Title
  
  J.Neurochem 110
  
  Pages: 1254-1262
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300145
[Journal Article] Mechanism underlying apolipoprotein E isoform-dependent lipid efflux from neural cells in culture2009
- Author(s)
  Minagawa H, Gong J-S, Jung C-G, Watanabe A, Lund-Katz S, Phillips M C, Saito H, Michikawa M.
- Journal Title
  
  J. Neurosci. Res
  
  Volume: 87 Pages: 2498-2508
- Data Source
  KAKENHI-PROJECT-21300145
[Journal Article] Apolipoprotein E4 (1-272) fragment is associated with mitochondrial proteins and affects mitochondrial function in neuronal cells.2009
- Author(s)
  Nakamura T, Watanabe A, Fujino T, Hosono T, Michikawa M
- Journal Title
  
  Mol.Neurodegener. 4
  
  Pages: 1-11
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20023040
[Journal Article] An E3 ubiquitin ligase, Synoviolin is involved in the degradation of immature Nicastrin, and regulates the production of amyloid ss-protein.2009
- Author(s)
  Maeda T, Marutani T, Zou K, Araki W, Yagishita N, Yamamoto Y, Amano T, Michikawa M, Nakajima T, Komano H.
- Journal Title
  
  FEBS J 276
  
  Pages: 5832-58401
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20023040
[Journal Article] Bioactive TGF°β can associate with lipoproteins and is enriched in those containtng apolipoprotein E32009
- Author(s)
  Tesseur I, Brecht W, Corn J, Gong J-S, Yanagisawa K, Michikawa M, Weisgraber K, Huang Y, Wyss-Coray T.
- Journal Title
  
  J.Neurochem 110
  
  Pages: 1254-1262
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20023040
[Journal Article] Microglia activated with toll-like receptor 9 ligand CpG attenuate oligomeric amyloid-β neurotoxicity in vitro and in vivo models of Alzheimer's disease.2009
- Author(s)
  Doi Y, Mizuno T, Maki Y, Jin S, Mizoguchi H, Ikeyama M, Doi M, Michikawa M Takeuchi H, Suzumura A
- Journal Title
  
  Am.J.Pathol. 175
  
  Pages: 2121-2132
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20023040
[Journal Article] Microglia activated with toll-like receptor 9 ligand CpG attenuate oligomeric amyloid-βneurotoxicity in vitro and in vivo models of Alzheimer's disease2009
- Author(s)
  Doi Y, Mizuno T, Maki Y, Jin S, Mizoguchi H, Ikeyama M, Doi M, Michikawa M, Takeuchi H, and Suzumura A.
- Journal Title
  
  Am. J. Pathol
  
  Volume: 175 Pages: 2121-2132
- Data Source
  KAKENHI-PROJECT-21300145
[Journal Article] An E3 ubiquitin ligase, synoviolin is involved in the degradation of immature nicastrin, and regulates the production of amyloidβ-protein2009
- Author(s)
  Maeda T, Marutani T, Zou K, Araki W, Yagishita N, Yamamoto Y, Amano T, Michikawa M, Nakajima T, and Komano H.
- Journal Title
  
  FEBS J
  
  Volume: 276 Pages: 5832-5840
- Data Source
  KAKENHI-PROJECT-21300145
[Journal Article] Mechanism underlying apolipoprotein E isoform-dependent lipid efflux from neural cells in culture.2009
- Author(s)
  Minagawa K, Gong J-S, Jung C-G, Watanabe A, Lund-Katz S, Phillips M C, Saito H, Michikawa M.
- Journal Title
  
  J.Neurosci.Res 87
  
  Pages: 2498-2508
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300145
[Journal Article] Aβ42-to-Aβ40- and angiotensin- converting activities in different domain of angiotensin-converting enzyme2009
- Author(s)
  Zou K, Maeda T, Oba R, Komano H, Michikawa M
- Journal Title
  
  J.Biol.Chem. 284
  
  Pages: 31914-31920
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20023040
[Journal Article] Aβ42-to-Aβ40-and angiotensin-converting activities in different domain of angiotensin-converting enzyme2009
- Author(s)
  Zou K, Maeda T, Oba R, Komano H, and Michikawa M
- Journal Title
  
  Biol. Chem
  
  Volume: 284 Pages: 31914-31920
- Data Source
  KAKENHI-PROJECT-21300145
[Journal Article] Apolipoprotein E4(1-272) fragment is associated with mitochondrial proteins and affects mitochondrial function in neuronal cells2009
- Author(s)
  Nakamura T, Watanabe A, Fujino T, Hosono T, and Michikawa M
- Journal Title
  
  Mol. Neurodegener
  
  Volume: 4 Pages: 35-35
- Data Source
  KAKENHI-PROJECT-21300145
[Journal Article] Apolipoprotein E4(1-272)fragment is associated with mitochondrial proteins and affects mitochondrial function in neuronal cells.2009
- Author(s)
  Nakamura T, Watanabe A, Fujino T, Hosono T, Michikawa M
- Journal Title
  
  Mol.Neurodegener. 4
  
  Pages: 1-11
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300145
[Journal Article] アポリポ蛋白Eはアミロイド蛋白βの分解を促進させる2008
- Author(s)
  道川誠
- Journal Title
  
  Cognition and Dementia 7
  
  Pages: 58-59
- Data Source
  KAKENHI-PROJECT-20023040
[Journal Article] コレステロール代謝とアルツハイマー病2008
- Author(s)
  道川誠
- Journal Title
  
  臨床検査 52
  
  Pages: 325-329
- Data Source
  KAKENHI-PROJECT-20023040
[Journal Article] Novel role of presenilins in maturation and transport of integrin β12008
- Author(s)
  Zou K, Hosono T, Nakamura T, Shiraishi H, Naeda T, Komano H, Yanagisawa K, Michikawa M
- Journal Title
  
  Biochemistry 47(11)
  
  Pages: 3370-3378
- Data Source
  KAKENHI-PROJECT-19300138
[Journal Article] New amyloid plaques or a game of hide-and-seek?2008
- Author(s)
  Zou K, Maeda T, Michikawa M, Komano H
- Journal Title
  
  Int J Biol Sci, 4
  
  Pages: 200-201
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300138
[Journal Article] New amyloid plaques or a game of hide-and-seek.2008
- Author(s)
  Kun Zou, Tomoji Maeda, Makoto Michikawa, Hiroto Komano
- Journal Title
  
  International Journal of Biological Sciences 4
  
  Pages: 200-201
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19800040
[Journal Article] Angiotensin-converting enzyme as a potential target for treament of Alzheimer's disease:inhibition or activation?2008
- Author(s)
  Kun Zou and Makoto Michikawa
- Journal Title
  
  Reviews in Neurosciences. (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19800040
[Journal Article] アルツハイマー病とスタチン2008
- Author(s)
  道川誠
- Journal Title
  
  BioClinica 23
  
  Pages: 52-57
- Data Source
  KAKENHI-PROJECT-19300138
[Journal Article] アポリポ蛋白E2008
- Author(s)
  道川誠
- Journal Title
  
  日本臨床 66
  
  Pages: 156-162
- Data Source
  KAKENHI-PROJECT-20023040
[Journal Article] Novel role of presenilins in maturation and transport of integrin β1.2008
- Author(s)
  Zou K, Hosono T, Nakamura T, Shiraishi H, Maeda T, Komano H, Yanagisawa K, Michikawa M.
- Journal Title
  
  Biochemistry 47
  
  Pages: 3370-3378
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20023040
[Journal Article] New amyloid plaques or a game of hide-and-seek?2008
- Author(s)
  Zou K, Maeda T, Michikawa M, Komano H
- Journal Title
  
  Int J Biol Sci 4
  
  Pages: 200-201
- Data Source
  KAKENHI-PROJECT-19300138
[Journal Article] Novel role of presenilins in maturation and transport of integrin β12008
- Author(s)
  Zou K, Hosono T, Nakamura T, Shiraishi H, Maeda T, Komano H, Yanagisawa K, Michikawa M.
- Journal Title
  
  Biochemistry 47
  
  Pages: 3370-3378
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18023046
[Journal Article] Angiotensin-Converting Enzyme as a Potential Target for Treatment of Alzheimer's Disease : Inhibition or Activation2008
- Author(s)
  Kun Zou and Makoto Michikawa
- Journal Title
  
  Rev Neurosci 19
  
  Pages: 203-212
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19800040
[Journal Article] Alzheimer 病研究の進歩と治療戦略2008
- Author(s)
  道川誠
- Journal Title
  
  医学のあゆみ「老化と疾患」-病態の理解と診断・治療の進歩別冊
  
  Pages: 39-46
- Data Source
  KAKENHI-PROJECT-19300138
[Journal Article] アルツハイマー病とスタチン2008
- Author(s)
  道川誠
- Journal Title
  
  BioClinica 23
  
  Pages: 52-57
- Data Source
  KAKENHI-PROJECT-20023040
[Journal Article] Novel role of presenilins in maturation and transport of integrinβ1.2008
- Author(s)
  Kun Zou, Takashi Hosono, Toshiyuki Nakamura, Hirohisa Shiraishi, Tomoji Maeda, Hiroto Komano, Katsuhiko Yanagisawa, Makoto Michikawa
- Journal Title
  
  Biochemistry 27
  
  Pages: 3370-3378
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19800040
[Journal Article] Angiotensin-converting enzyme as a potential target for treatment of Alzheimer's disease : Inhibition or activation?2008
- Author(s)
  Zou K, Michikawa M
- Journal Title
  
  Rev Neurosci 19
  
  Pages: 203-212
- Data Source
  KAKENHI-PROJECT-19300138
[Journal Article] New amyloid plaques or a game of hide-and-seek2008
- Author(s)
  Kun, Zou, Tomoji, Maeda, Makoto, Michikawa and Hiroto, Komano
- Journal Title
  
  Int J Biol Sci 4
  
  Pages: 200-201
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19800040
[Journal Article] アポリポ蛋白E2008
- Author(s)
  道川誠
- Journal Title
  
  日本臨床 66
  
  Pages: 156-162
- Data Source
  KAKENHI-PROJECT-19300138
[Journal Article] New amyloid plaques or a game of hide-and-seek?2008
- Author(s)
  Zou K, Maeda T, Michikawa M, and Komano H.
- Journal Title
  
  Int J Biol Sci, 4
  
  Pages: 200-201
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20023040
[Journal Article] Novel role of presenilins in maturation and transport of integrin β12008
- Author(s)
  Zou K, Hosono T, Nakamura T, Shiraishi H, Maeda T, Komano H, Yanagisawa K, Michikawa M
- Journal Title
  
  Biochemistry 47
  
  Pages: 3370-3378
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300138
[Journal Article] Novel role of presenilins in maturation and transport of integrin β1.2008
- Author(s)
  Kun Zou, Takashi Hosono, Toshiyuki Nakamura, Hirohisa Shiraishi, Tomoji Maeda, Hiroto Komano, Katsuhiko Yanagisawa and Makoto Michikawa
- Journal Title
  
  Biochemishy 47
  
  Pages: 3370-3378
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19800040
[Journal Article] Alzheimer病研究の進歩と治療戦略2008
- Author(s)
  道川誠.
- Journal Title
  
  医学のあゆみ「老化と疾患」-病態の理解と診断・治療の進歩別冊
  
  Pages: 39-46
- Data Source
  KAKENHI-PROJECT-20023040
[Journal Article] Angiotensin-converting enzyme as a potential target for treatment of Alzheimer's disease : inhibition or activation.2008
- Author(s)
  Kun Zou, Makoto Michikawa
- Journal Title
  
  Reviews in Neurosciences 19
  
  Pages: 203-212
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19800040
[Journal Article] Novel role of presenilins in maturation and transport of integrin β1.2008
- Author(s)
  Zou K, Hosono T, Nakamura T, Shiraishi H, Maeda T, Komano H, Yanagisawa K, Michikawa M.
- Journal Title
  
  Biochemistry 47
  
  Pages: 3370-3378
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300138
[Journal Article] コレステロール代謝とアルツハイマー病2008
- Author(s)
  道川誠
- Journal Title
  
  臨床検査 52
  
  Pages: 325-329
- Data Source
  KAKENHI-PROJECT-19300138
[Journal Article] Novel role of presenilins in maturation and transport of integrin beta12008
- Author(s)
  Kun Zou, Takashi Hosono, Toshiyuki Nakamura, Hirohisa Shiraishi, Tomoji Maeda, Hiroto Komano, Katsuhiko Yanagisawa and Makoto Michikawa
- Journal Title
  
  Biochemistry 47
  
  Pages: 3370-3378
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19800040
[Journal Article] アポリポ蛋白Eはアミロイド蛋白βの分解を促進させる2008
- Author(s)
  道川誠
- Journal Title
  
  Cognition and Dementia 7
  
  Pages: 58-59
- Data Source
  KAKENHI-PROJECT-19300138
[Journal Article] Novel action of apolipoprotein E (ApoE) : ApoE isoform specifically inhibits lipid-partide-mediated cholesterol release from neurons2007
- Author(s)
  Gong JS, Morita SY, Kobayashi M, Handa T, Fujita SC, Yanagisawa K, Michikawa M
- Journal Title
  
  Mol Neurodegener 2
  
  Pages: 9-9
- Data Source
  KAKENHI-PROJECT-19300138
[Journal Article] A ganglioside-induced toxic soluble Aβ assembly. Its enhanced formation from Aβ bearing the Arctic mutation.2007
- Author(s)
  Yamamoto N, Matsubara E, Maeda S, Minagawa H, Takashima A, Maruyama W, Michikawa M, Yanagisawa K
- Journal Title
  
  J Biol Chem 282(4)
  
  Pages: 2646-2655
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300138
[Journal Article] Novel action of apolipoprotein E(ApoE) : ApoE isoform specifically inhibits lipid-particle-mediated cholesterol release from neurons.2007
- Author(s)
  Gong JS, Morita SY, Kobayashi M, Handa T, Fujita SC, Yanagisawa K, Michikawa M.
- Journal Title
  
  Mol Neurodegeneration 2:9
  
  Pages: 1-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300138
[Journal Article] Angiotensin-converting enzyme converts amyloid β-protein 1-42(Aβ(1-42)to Aβ((1-40), and its inhibition enhances brain Aβ deposition.2007
- Author(s)
  Kun Zou, Haruyasu Yamaguchi, Hiroyasu Akatsu, Takaaki Sakamoto, Mihee Ko, Kazushige Mizoguchi, Jian-S heng Gong, Wenxin Yu, Takayuki Yamamoto, Kenji Kosaka, Katsuhiko Yanagisawa and Makoto Michikawa.
- Journal Title
  
  Journal of Neuroscience 27
  
  Pages: 8628-8635
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19800040
[Journal Article] Angiotensin-converting enzyme converts amyloid β-protein1-42 (Aβ(1-42)) to Aβ(1-40), and its inhibition enhances brain Aβ deposition2007
- Author(s)
  Zou K, Yamaguchi H, Akatsu H, Sakamoto T, Ko M, Mizoguchi K, Gong JS, Yu W, Yamamoto T, Kosaka K, Yanagisawa K, Michikawa M
- Journal Title
  
  J Neurosci. 27(32)
  
  Pages: 8628-8635
- Data Source
  KAKENHI-PROJECT-19300138
[Journal Article] Alteration of the glutamate and GABA transporters in the hippocampus of the Niemann-Pick disease, type C mouse using proteomic analysis.2007
- Author(s)
  Byun K, Kim J, Cho S-Y, Hutchinson B, Yang S-R, Kang K-S, Cho M, Hwang K, Michikawa M, Jeon Y-W, Paik Y-K, Lee B
- Journal Title
  
  Proteomics 282
  
  Pages: 2646-2655
- Data Source
  KAKENHI-PROJECT-18023046
[Journal Article] A ganglioside-induced toxic soluble Aβ assembly. Its enhanced formation from Aβ bearing the Arctic mutation2007
- Author(s)
  Yamamoto N, Matsubara E, Maeda S, Minagawa H, Takashima A, Maruyama W, Michikawa M, Yanagisawa K
- Journal Title
  
  J Biol Chem 282(4)
  
  Pages: 2646-2655
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18023046
[Journal Article] Angiotensin-converting enzyme converts amyloid β-protein1-42(Aβ(1-42))to Aβ(1-40), and its inhibition enhances brain Aβ deposition2007
- Author(s)
  Zou K, Yamaguchi H, Akatsu H, Sakamoto T, Ko M, Mizoguchi K, Gong JS, Yu W, Yamamoto T, Kosaka K, Yanagisawa K, Michikawa M.
- Journal Title
  
  J Neurosci 27(32)
  
  Pages: 8628-8635
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300138
[Journal Article] Novel action of apolipoprotein E (ApoE): ApoE isoform specifically inhibits lipid-particle-mediated cholesterol release from nearons2007
- Author(s)
  Gong JS, Morita SY, Kobayashi M, Handa T, Fujita SC, Yanagisawa K, Michikawa M.
- Journal Title
  
  Mol Neurodegeneration 2:9
  
  Pages: 1-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18023046
[Journal Article] Angiotensin-converting enzyme converts amyloid β-proteinl-42(Aβ(1-42)) to Aβ(1-40), and its inhibition enhances brain Aβ deposition2007
- Author(s)
  Zou K, Yamaguchi H, Akatsu H, Sakamoto T, Ko M, Mizoguchi K, Gong JS, Yu W, Yamamoto T, Kosaka K, Yanagisawa K, Michikawa M.
- Journal Title
  
  J Neurosci 27(32)
  
  Pages: 8628-8635
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18023046
[Journal Article] Angiotensin-converting enzyme converts Aβ1-42 to Aβ1-40 and its inhibition enhances brain Aβ deposition2007
- Author(s)
  Kun Zou, Haruyasu Yamaguchi, Hiroyasu Akatsu, Takaaki Sakamoto, Mihee Ko, Kazushige Mizoguchi, Jian-Sheng Gong, Wenxin Yu, Takayuki Yamamoto, Kenji Kosaka, Katsuhiko Yanagisawa and Makoto Michikawa
- Journal Title
  
  J Neurosci 27
  
  Pages: 8628-8635
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19800040
[Journal Article] A ganglioside-induced toxic soluble Aβ assembly. Its enhanced formation from Aβ bearing the Arctic mutation2007
- Author(s)
  amamoto N, Matsubara E, Maeda S, Minagawa H, Takashima A, Maruyama W, Michikawa M, Yanagisawa K
- Journal Title
  
  J Biol Chem. 282(4)
  
  Pages: 2646-2655
- Data Source
  KAKENHI-PROJECT-19300138
[Journal Article] Role of cholesterol in amyloid cascade : cholesterol-dependent modulation of tau phosphorylation and mitochondrial function.2006
- Author(s)
  Michikawa M.
- Journal Title
  
  Acta Neurol Scand Suppl. 6(4)
  
  Pages: 1230-1236
- Data Source
  KAKENHI-PROJECT-18023046
[Journal Article] Ethnicity-dependent genetic association of ABCA2 with sporadic Alzheimer's disease.2006
- Author(s)
  Wollmer MA, Kapaki E, Hersberger M, Muntwyler J, Brunner F, Tsolaki M, Akatsu H, Kosaka K, Michikawa M, Molyva D, Paraskevas GP, Lutjohann D, von Eckardstein A, Hock C, Nitsh RM, Papassotiropoulos A
- Journal Title
  
  Am J Med Genet B Neuropsychiatr Genet 185
  
  Pages: 21-26
- Data Source
  KAKENHI-PROJECT-18023046
[Journal Article] A ganglioside-induced toxic soluble Aβ assembly.2006
- Author(s)
  Yamamoto N, Matsubara E, Maeda S, Minagawa H, Takashima A, Maruyama W, Michikawa M, Yanagisawa K
- Journal Title
  
  J Biol Chem 24(2)
  
  Pages: 292-298
- Data Source
  KAKENHI-PROJECT-18023046
[Journal Article] NPC1 gene deficiency leads to lack of neural stem cell self-renewal and abnormal differentiation through activation of p38 MAP kinase signaling.2006
- Author(s)
  Yang SR, Kim SJ, Byun KH, Hutchinson B, Lee HH, Michikawa M, Lee YS, Kang KS
- Journal Title
  
  Stem Cells 141(5)
  
  Pages: 534-536
- Data Source
  KAKENHI-PROJECT-18023046
[Journal Article] Association between cognitive function and plasma lipids of the elderly after controlling for apolipoprotein E genotype
- Author(s)
  Yasuno F, Tanimukai S, Sasaki M, Hidaka S, Ikejima C, Yamashita F, Kodama C, Mizukami K, Michikawa M, Asada T.
- Journal Title
  
  Am. J. Geriat. Psychiat
  
  Volume: (in press)
- Data Source
  KAKENHI-PROJECT-21300145
[Journal Article] Mechanism underlying apolipoprotein E isoform-dependent lipid efflux from neural cells in culture.
- Author(s)
  Minagawa K, Gong J-S, Jung C-G, Watanabe A, Lund-Katz S, Phillips M C, Saito H, and Michikawa M.
- Journal Title
  
  J Neurosci Res (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20023040
[Journal Article] Mechanism underlying apolipoprotein E isoform-dependent lipid efflux from neural cells in culture
- Author(s)
  Minagawa K, Gong J-S, Jung C-G, Watanabe A, Lund-Katz S, Phillips M C, Saito H, Michikawa M
- Journal Title
  
  J Neurosci Res (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300138
[Patent] アポリポ蛋白E産生促進用組成物2018
- Inventor(s)
  道川誠,湯田直樹、田中美順
- Industrial Property Rights Holder
  道川誠,湯田直樹、田中美順
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2018-154553
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-16H05559
[Patent] 認知機能改善用組成物2018
- Inventor(s)
  道川誠、鄭　且均、若林裕之、中野学、武藤夏美
- Industrial Property Rights Holder
  道川誠、鄭　且均、若林裕之、中野学、武藤夏美
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2018-190251
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-16H05559
[Patent] アルツハイマー病バイオマーカー2018
- Inventor(s)
  道川誠、赤津裕康、アブドラモハンマド、松原悦朗、木村成志
- Industrial Property Rights Holder
  道川誠、赤津裕康、アブドラモハンマド、松原悦朗、木村成志
- Industrial Property Rights Type
  特許
- Filing Date
  2018
- Overseas
- Data Source
  KAKENHI-PROJECT-16H05559
[Patent] 脳内の細胞外シグナル制御キナーゼリン酸化促進用組成物2018
- Inventor(s)
  道川誠、鄭　且均、若林裕之、中野学、武藤夏美
- Industrial Property Rights Holder
  道川誠、鄭　且均、若林裕之、中野学、武藤夏美
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2018-190255
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-16H05559
[Patent] アルツハイマー病の予防及び治療薬並びにアルツハイマー病の予防及び治療薬のスクリーニング方法2009
- Inventor(s)
  道川誠、西辻和親
- Industrial Property Rights Holder
  財団法人ヒューマンサイエンス振興財団
- Industrial Property Number
  2009-289487
- Filing Date
  2009-12-21
- Data Source
  KAKENHI-PROJECT-21300145
[Patent] アルツハイマー病の予防及び治療薬並びにアルツハイマー病の予防及び治療薬のスクリーニング方法2009
- Inventor(s)
  道川誠、西辻和親
- Industrial Property Rights Holder
  財団法人ヒューマンサイエンス振興財団
- Industrial Property Number
  2009-289487
- Filing Date
  2009-12-21
- Data Source
  KAKENHI-PROJECT-20023040
[Patent] アルツハイマー病の予防及び治療薬並びにアルツハイマー病の予防及び治療薬のスクリーニング方法2009
- Inventor(s)
  道川誠、西辻和親
- Industrial Property Rights Holder
  財団法人ヒューマンサイエンス振興財団
- Filing Date
  2009-12-21
- Data Source
  KAKENHI-PROJECT-21300145
[Presentation] Insulin deficiency increases Sirt2 level in streptozotocin-treated Alzheimer’s disease-like mouse model: Sirt2 increases tau phosphorylation through ERK activation2022
- Author(s)
  Chunyu Zhou, Cha-Gyun Jung, Mi-Jeong Kim, Atsushi Watanabe, Mona Abdelhamid, Ferdous Taslima and Makoto Michikawa
- Organizer
  Neuro2022
- Data Source
  KAKENHI-PROJECT-20K07762
[Presentation] Sustained high body temperature exacerbates cognitive function and Alzheimer’s disease-related pathologies2022
- Author(s)
  Cha-Gyun Jung, Reiko Kato, Chunyu Zhou, Mona Abdelhamid, Hitoshi Yamashita, Makoto Michikawa
- Organizer
  Neuro2022
- Data Source
  KAKENHI-PROJECT-20K07762
[Presentation] Effect of sustained high body temperature on cognitive function2022
- Author(s)
  Cha-Gyun Jung, Reiko Kato, Chunyu Zhou, Mona Abdelhamid, Hitoshi Yamashita, Makoto Michikawa.
- Organizer
  第41回認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-20K07762
[Presentation] ビフィズス菌MCC1274のアルツハイマー病病態関連分子に対する影響の検討2022
- Author(s)
  Mona Abdelhamid, Chunyu Zhou, Cha-Gyun Jung, Makoto Michikawa.
- Organizer
  第41回認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-20K07762
[Presentation] Sirt2 increases tau phosphorylation through ERK activation2022
- Author(s)
  Chunyu Zhou, Cha-Gyun Jung, Mi-Jeong Kim, Atsushi Watanabe, Mona Abdelhamid, Ferdous Taslima and Makoto Michikawa.
- Organizer
  第41回認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-20K07762
[Presentation] Effect of Tid1 on the mitochondrial accumulation of APP.2021
- Author(s)
  Jung CG, Zhou CY, Abdelhamid M, Ferdous T, Shaaban I. E, Michikawa M.
- Organizer
  第40回認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-20K07762
[Presentation] Effect of ATBF1 on tau phosphorylation.2021
- Author(s)
  Zhou CY, Jung CG, Abdelhamid M, Ferdous T, Shaaban I. E, Michikawa M.
- Organizer
  第40回認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-20K07762
[Presentation] アルツハイマー病モデルマウスにおけるビフィズス菌摂取による認知機能改善作用とアミロイドβ産生低下作用。2021
- Author(s)
  Mona Abdelhamid, Cha-Gyun Jung, Chunyu Zhou, Ferdous Taslima, Mohammad Abdullah, Makoto Michikawa
- Organizer
  第25回腸内細菌学会
- Data Source
  KAKENHI-PROJECT-20K07762
[Presentation] Effect of Bifidobacterium breve MCC1274 on the pathogenesis of Alzheimer’s disease.2021
- Author(s)
  Mona Abdelhamid, Chunyu Zhou, Kazuya Ohno, Tetsuya Kuhara, Ferdous Taslima, Mohammad Abdullah, Cha-Gyun Jung, Makoto Michikawa.
- Organizer
  第40回認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-20K07762
[Presentation] Probiotic Bifidobacterium breve decreases Aβ production via the upregulation of ADAM10 level and attenuates microglia activation in APP knock-in mouse model of Alzheimer’s disease.2021
- Author(s)
  Cha-Gyun Jung, Mona Abdelhamid, Chunyu Zhou, Kazuya Ohno, Tetsuya Kuhara, Ferdous Taslima, Mohammad Abdullah, Makoto Michikawa.
- Organizer
  Alzheimer’s Association International Conference 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07762
[Presentation] アルツハイマー病の血液バイオマーカー2020
- Author(s)
  道川　誠
- Organizer
  第39回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-20K07861
[Presentation] Effect of lactoferrin on the memory impairment and pathogenesis of Alzheimer's disease2020
- Author(s)
  鄭　且均、Abdelhamid Mona、周春雨、Abdullah Mohammad、道川　誠
- Organizer
  日本ラクトフェリン学会第9回学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-20K07762
[Presentation] Vessels meet dementia-共通版を探るーアルツハイマー病の分子病態とApoE2020
- Author(s)
  道川　誠
- Organizer
  第52回日本動脈硬化学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-20K07861
[Presentation] Genome-wide Analysis of Dementia-related Genes in Mouse Hippocampus by P. gingivalis -LPS.2019
- Author(s)
  Morikawa T, Uehara O, Harada F, Hiraki D, Onishi A, Takai R, Yoshida K, Sato J, Nishimura M, Chiba I, Michikawa M, Abiko A.
- Organizer
  IADR 97th General Session and Exhibition
- Data Source
  KAKENHI-PROJECT-17K11681
[Presentation] Regulation　of　expression　and　release　of　ApoE　in　cultured　astrocytes2018
- Author(s)
  アブドラ　モハンマド、フェルドス　タスリマ、キョウ建生、鄭　且均、道川　誠
- Organizer
  日本認知症学会
- Data Source
  KAKENHI-PROJECT-16H05559
[Presentation] Iron-treatment　enhances　γ-secretase　activity　and　inhibits　amyloid　depostion2018
- Author(s)
  鄒　鶤、沈　雪峰、藤田　融、菊地　光太、Arshad　Noorani、Sadequl　Islam、　駒野　宏人、道川　誠
- Organizer
  日本認知症学会
- Data Source
  KAKENHI-PROJECT-16H05559
[Presentation] 認知症の危険因子・防御因子2018
- Author(s)
  道川　誠
- Organizer
  日本認知症学会
- Data Source
  KAKENHI-PROJECT-16H05559
[Presentation] 歯の喪失がアルツハイマー病を誘発させるメカニズムについて2018
- Author(s)
  後藤　哲哉、倉本　恵梨子、　ダール　アシス、松本　信英、原　博満、山中　淳之、岩井　治樹、道川　誠
- Organizer
  日本認知症学会
- Data Source
  KAKENHI-PROJECT-16H05559
[Presentation] Analysis　of　phospholipid　species　in　AD　model　mouse　brain　by　LC-MS/MS2018
- Author(s)
  Haque　MD,　Sheikh　Abdullah、長子　晴美、堺　弘道、Azad 　Abul, 土屋　美加子、道川　誠、長井　篤
- Organizer
  日本認知症学会
- Data Source
  KAKENHI-PROJECT-16H05559
[Presentation] 細胞内アダプター分子X11Lを介したApoE4による細胞内情報伝達機構の解明2018
- Author(s)
  郭　家伶、豊田　めぐみ、中矢　正、道川　誠、鈴木　利治
- Organizer
  日本認知症学会
- Data Source
  KAKENHI-PROJECT-16H05559
[Presentation] Effect　of　lactoferrin　on　ApoE　secretion　from　cultured　astrocytes2018
- Author(s)
  Jung CG,　Abdelhamid　M,　Abdullah　M,　Zhou　CY,　Wakabayashi H,　Yamauchi　K,　Abe　F,　Michikawa　M
- Organizer
  日本認知症学会
- Data Source
  KAKENHI-PROJECT-16H05559
[Presentation] グリア細胞におけるABCA7発現制御機構の検討2016
- Author(s)
  市野晨人、奥平桂一郎、川原遙華、木村仁、辻大輔、西辻和親、堂前純子、道川誠、坂下直実、伊藤孝司、斎藤博幸
- Organizer
  日本薬学会第136年会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-25293006
[Presentation] 歯周病・咀嚼機能低下がアルツハイマー病分子病態ならびに認知機能に及ぼす影響2016
- Author(s)
  道川誠
- Organizer
  第6回日本認知症予防学会
- Place of Presentation
  東北大学（宮城県、仙台市）
- Year and Date
  2016-09-23
- Data Source
  KAKENHI-PROJECT-16H05559
[Presentation] 認知症の正しい理解と歯科・口腔疾患との関連2016
- Author(s)
  道川誠
- Organizer
  第61回日本口腔外科学会
- Place of Presentation
  幕張メッセ（千葉県、千葉市）
- Invited
- Data Source
  KAKENHI-PROJECT-16H05559
[Presentation] 歯周病、咀嚼機能低下がアルツハイマー病分病態ならびに認知機能に及ぼす影響2016
- Author(s)
  道川　誠
- Organizer
  第6回日本認知症予防学会
- Place of Presentation
  東北大学（宮城県、仙台市）
- Year and Date
  2016-09-23
- Data Source
  KAKENHI-PROJECT-15K15712
[Presentation] ABCA7遺伝子型とファゴサイトーシス活性2016
- Author(s)
  堂前純子, 高瀬弘嗣, 吉武仙達, 道川誠
- Organizer
  日本動脈硬化学会（東京都新宿区）
- Place of Presentation
  京王プラザホテル
- Data Source
  KAKENHI-PROJECT-25461375
[Presentation] グリア細胞における ABCA7 発現制御機構の検討2016
- Author(s)
  市野晨人, 奥平桂一郎, 川原遥華, 木村仁, 辻大輔, 西辻和親, 堂純子, 道川誠, 坂下直実, 伊藤孝司, 斎藤博幸
- Organizer
  日本薬学会
- Place of Presentation
  横浜　パシフィコ横浜
- Year and Date
  2016-03-29
- Data Source
  KAKENHI-PROJECT-25461375
[Presentation] 認知症の正しい理解と歯科・口腔疾患との関連2016
- Author(s)
  道川　誠
- Organizer
  第61回日本口腔外科学会総会
- Place of Presentation
  幕張メッセ（千葉県、千葉市）
- Invited
- Data Source
  KAKENHI-PROJECT-15K15712
[Presentation] 特別講演：歯周病・咀嚼機能低下がアルツハイマー病分子病態・認知機能に及ぼす影響2015
- Author(s)
  道川　誠
- Organizer
  北海道医療大学招待講演
- Place of Presentation
  北海道医療大学（北海道石狩郡当別町）
- Year and Date
  2015-07-28
- Invited
- Data Source
  KAKENHI-PROJECT-15K15712
[Presentation] 歯周病・咀嚼機能低下がアルツハイマー病分子病態・認知機能に及ぼす影響2015
- Author(s)
  道川　誠
- Organizer
  日本歯科大学新潟生命歯学科
- Place of Presentation
  日本歯科大学新潟生命歯学部（新潟県新潟市）
- Year and Date
  2015-09-07
- Invited
- Data Source
  KAKENHI-PROJECT-15K15712
[Presentation] Arachidonic or docosahezanenoic acid diet attenuates Ab deposition and prevents memory impairment in Tg2576 mice.2015
- Author(s)
  Makoto Michikawa
- Organizer
  Aging and Neurodegenerative Disease. 2015 Ilsong Mini Symposium. Korea
- Place of Presentation
  韓国
- Year and Date
  2015-11-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15712
[Presentation] 特別講演：認知症の正しい理解と歯科医療との関わりにおける最新知見2015
- Author(s)
  道川　誠
- Organizer
  日本歯科大学公開フォーラム
- Place of Presentation
  日本歯科大学（東京都千代田）
- Year and Date
  2015-09-06
- Invited
- Data Source
  KAKENHI-PROJECT-15K15712
[Presentation] 認知症と脂質異常症・血管性要因2015
- Author(s)
  道川　誠
- Organizer
  第34回日本認知症学会学術集会
- Place of Presentation
  リンクステーションホール（青森県青森市）
- Year and Date
  2015-10-02
- Data Source
  KAKENHI-PROJECT-15K15712
[Presentation] ApoE4ノックインマウスの認知機能障害に対する長期的な自発的運動の治療的効果の検討2015
- Author(s)
  杉山佳隆, 高松泰行, 早稲田雄也, 加藤寛聡, 玉越敬悟, 道川誠, 石田和人
- Organizer
  第2回日本基礎理学療法学会学術集会・日本基礎理学療法学会第20回学術大会合同大会
- Place of Presentation
  横須賀市
- Year and Date
  2015-11-14
- Data Source
  KAKENHI-PROJECT-26350610
[Presentation] SAA turnover is modulated by ABCA12014
- Author(s)
  Sumiko Abe-Dohmae, Yuji Isono, Shinji Yokoyama, Makoto Michikawa
- Organizer
  日本動脈硬化学会
- Place of Presentation
  東京　京王プラザホテル
- Year and Date
  2014-07-11
- Data Source
  KAKENHI-PROJECT-25461375
[Presentation] Serum amyloid Aの代謝回転とABCA12014
- Author(s)
  堂前純子, 磯野裕司, 横山信治, 道川誠
- Organizer
  日本生化学会
- Place of Presentation
  京都　国立京都国際会館
- Year and Date
  2014-10-18
- Data Source
  KAKENHI-PROJECT-25461375
[Presentation] SAA turnover is modulated by ABCA12014
- Author(s)
  Sumiko Abe-Dohmae, Yuji Isono, Shinji Yokoyama, Makoto Michikawa
- Organizer
  第46回日本動脈硬化学会総会・学術集会
- Place of Presentation
  京王プラザホテル (新宿）
- Data Source
  KAKENHI-PROJECT-25461375
[Presentation] ApoE dependent and independent Abeta clearance pathways in the brain2012
- Author(s)
  Michikawa M
- Organizer
  Mount Sinai University, School of Medicine
- Place of Presentation
  New York, NY, USA
- Year and Date
  2012-01-06
- Data Source
  KAKENHI-PROJECT-21300145
[Presentation] Aβ43変換活性におけるACEの二つ活性ドメインの役割2011
- Author(s)
  鄒鶤、劉俊俊、劉殊余、田邉千晶、前田智司、渡邉淳、道川誠、駒野宏人
- Organizer
  第54回日本神経化学会大会
- Place of Presentation
  石川県加賀市
- Data Source
  KAKENHI-PROJECT-22700399
[Presentation] Isoform-dependent and-independent functions of apolipoprotein E and Alzheimer disease2011
- Author(s)
  Michikawa M
- Organizer
  The International Conference of Korean Society for Gerontology
- Place of Presentation
  Busan, Korea
- Year and Date
  2011-07-09
- Data Source
  KAKENHI-PROJECT-21300145
[Presentation] 高齢者認知機能の経時変化に及ぼす血中脂質濃度、血圧およびApoE遺伝子多型の影響2011
- Author(s)
  安野史彦、谷向知、佐々木恵、日高真、池嶋千秋、山下典生、児玉千稲、水上勝義、道川誠、朝田隆
- Organizer
  日本認知症学会
- Place of Presentation
  東京
- Year and Date
  2011-11-11
- Data Source
  KAKENHI-PROJECT-21300145
[Presentation] Two active domains of ACE are essential for Aβ43-converting activity2011
- Author(s)
  Kun Zou, Junjun Liu, Atsushi, Watanabe, Shuyu Liu, Chiaki tanabe, Tomoji Maeda, Ryutaro Oba, Makoto Michikawa, Hiroto Komano
- Organizer
  23^<rd> Biennial Meeting of International Society for Neuro chemistry
- Place of Presentation
  Athens, Greece
- Year and Date
  2011-08-31
- Data Source
  KAKENHI-PROJECT-22700399
[Presentation] The renin-angiotensin system modulates APP and ApoE metabolism2011
- Author(s)
  山内玲奈、ゾウクン、鄭且均、道川誠
- Organizer
  日本認知症学会
- Place of Presentation
  東京
- Year and Date
  2011-11-11
- Data Source
  KAKENHI-PROJECT-21300145
[Presentation] アルツハイマー病の分子病態/認知機能に対するアラキドン酸摂取の影響2011
- Author(s)
  道川誠
- Organizer
  認知症サプリメント研究会
- Place of Presentation
  東京
- Year and Date
  2011-03-19
- Data Source
  KAKENHI-PROJECT-21300145
[Presentation] Arachidonic acid diet prevents memory impairment and brain Abeta deposition in Tg2576 mice2011
- Author(s)
  Michikawa M
- Organizer
  Symposium : PUFA and its derivatives-brain, neuroprotective agents for senescence, ISN-ESN
- Place of Presentation
  Athens, Greece
- Year and Date
  2011-08-30
- Data Source
  KAKENHI-PROJECT-21300145
[Presentation] Isoform-dependent functions of apolipoprotein E and Alzheimer disease2011
- Author(s)
  Michikawa M
- Organizer
  The department seminar at Mayo Clinic
- Place of Presentation
  Mayo Clinic, Jacksonville, USA
- Year and Date
  2011-06-08
- Data Source
  KAKENHI-PROJECT-21300145
[Presentation] Isoform-dependent and-independent functions of apolipoprotein E and Alzheimer disease2011
- Author(s)
  Michikawa M
- Organizer
  日本生化学会大会シンポジウム
- Place of Presentation
  京都
- Year and Date
  2011-09-23
- Data Source
  KAKENHI-PROJECT-21300145
[Presentation] Two active domains of ACE are essential for Aβ43-converting activity2011
- Author(s)
  鄒鶤、劉俊俊、渡邉淳、劉殊余、田邉千晶、前田智司、大葉龍太郎、道川誠、駒野宏人
- Organizer
  第23回国際神経化学会国際会議
- Place of Presentation
  アテネ
- Data Source
  KAKENHI-PROJECT-22700399
[Presentation] Two active domains of ACE are essential for Abeta43-conver ting activity2011
- Author(s)
  Zou K, Liu J, Watanabe A, Liu S, Tanabe C, Maeda T, Oba R, Michikawa M, Komano H
- Organizer
  The International Conference of Korean Society for Gerontology
- Place of Presentation
  Athens, Greece
- Year and Date
  2011-08-30
- Data Source
  KAKENHI-PROJECT-21300145
[Presentation] アルツハイマー病分子病態ならびに認知機能障害に対する不飽和脂肪酸経口摂取の影響2011
- Author(s)
  道川誠
- Organizer
  日本基礎老化学会第34回大会シンポジウム
- Place of Presentation
  東京
- Year and Date
  2011-06-17
- Data Source
  KAKENHI-PROJECT-21300145
[Presentation] 脳内脂質代謝変動とアルツハイマー病分子病態2011
- Author(s)
  道川誠
- Organizer
  第5回関西・中部認知症学会
- Place of Presentation
  名古屋
- Year and Date
  2011-02-19
- Data Source
  KAKENHI-PROJECT-21300145
[Presentation] Aβ343変換活性におけるACEの二つ活性ドメインの役割2011
- Author(s)
  鄒鶤、劉俊俊、劉妹余、田邉千晶、前田智司、渡邉淳、道川誠、駒野宏人
- Organizer
  第54回日本神経化学会大会
- Place of Presentation
  石川県加賀市
- Year and Date
  2011-09-26
- Data Source
  KAKENHI-PROJECT-22700399
[Presentation] 脳内脂質代謝は、アルツハイマー病発症に関わりうるか2011
- Author(s)
  道川誠
- Organizer
  第8回アルツハイマー病の早期診断・治療・予防法の開発研究会
- Place of Presentation
  名古屋
- Year and Date
  2011-02-18
- Data Source
  KAKENHI-PROJECT-21300145
[Presentation] 血液脳関門機能に対するアポリポタンパク質Eアイソフォームの影響2010
- Author(s)
  西辻和親、細野崇、中村俊行、道川誠
- Organizer
  Neuro2010
- Place of Presentation
  神戸
- Year and Date
  2010-09-04
- Data Source
  KAKENHI-PROJECT-21300145
[Presentation] 炎症とアルツハイマー病2010
- Author(s)
  道川誠
- Organizer
  日本歯周病学会シンポジウム
- Place of Presentation
  高松
- Year and Date
  2010-09-19
- Data Source
  KAKENHI-PROJECT-21300145
[Presentation] APP代謝及びAb産生におけるATBF1の機能解析2010
- Author(s)
  厳景玉、赤津裕康、三浦裕、道川誠、鄭且均
- Organizer
  第29回日本認知症学会
- Place of Presentation
  名古屋
- Year and Date
  2010-11-05
- Data Source
  KAKENHI-PROJECT-21300145
[Presentation] Apolipoprotein E and Alzheimer's Disease2010
- Author(s)
  道川誠
- Organizer
  中国瀋陽医学院・何氏視覚科学学院
- Place of Presentation
  瀋陽、中国
- Year and Date
  2010-09-27
- Data Source
  KAKENHI-PROJECT-21300145
[Presentation] ACE阻害によるアルツハイマー病モデルマウス脳内変化の解析2010
- Author(s)
  鄒鶤、劉俊俊、劉〓余、田邉千晶、前田智司、道川誠、駒野宏人
- Organizer
  第53回日本神経化学学会、第33回日本神経科学大会、第20回日本神経回路学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-09-02
- Data Source
  KAKENHI-PROJECT-22700399
[Presentation] Effect of apolipoprotein E isofrom on formation and maintenance of blood-brain-barrier function2010
- Author(s)
  Kazuchika N, Hosono T, Nakamura T, and Michikawa M.
- Organizer
  Washington University, St
- Place of Presentation
  Louis, USA
- Year and Date
  2010-06-07
- Data Source
  KAKENHI-PROJECT-21300145
[Presentation] Potent inhibition of ACE leads to Alzheimer-like pathology in APP transgenic mouse brain.2010
- Author(s)
  Zou K, Liu S, Liu J, Tanabe C, Maeda T, Michikawa M, Komano H.
- Organizer
  International Conference on Alzheimer's Disease (ICAD)
- Place of Presentation
  Honolulu, Hawaii
- Year and Date
  2010-07-11
- Data Source
  KAKENHI-PROJECT-21300145
[Presentation] アルツハイマー病とスタチン2010
- Author(s)
  道川誠
- Organizer
  脳を護る-認知症を防ぐ-興和創薬・名古屋医師会共催シンポジウム
- Place of Presentation
  名古屋
- Year and Date
  2010-06-17
- Data Source
  KAKENHI-PROJECT-21300145
[Presentation] Enhanced Alzheimer's-like pathology by ACE inhibition in APP transgenic mouse brain2010
- Author(s)
  鄒鶤、劉俊俊、劉殊余、田邉千晶、前田智司、道川誠、駒野宏人
- Organizer
  第29回日本認知症学会学術集会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-22700399
[Presentation] アルツハイマー病とスタチン脳を護るー認知症を防ぐー興和創薬2010
- Author(s)
  道川誠
- Organizer
  名古屋医師会共催シンポジウム
- Place of Presentation
  名古屋
- Year and Date
  2010-06-17
- Data Source
  KAKENHI-PROJECT-21300145
[Presentation] ACE阻害によるアルツハイマー病モデルマウス脳内変化の解析2010
- Author(s)
  鄒鶤、劉俊俊、劉殊余、田邉千晶、前田智司、道川誠、駒野宏人
- Organizer
  第53回日本神経化学学会、第33回日本神経科学大会、第20回日本神経回路学会大会合同大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22700399
[Presentation] Enhanced Alzheimer's-like pathology by ACE inhibition in APP transgenic mouse brain.2010
- Author(s)
  鄒鶤、劉俊俊、劉〓余、田邉千晶、前田智司、道川誠、駒野宏人
- Organizer
  第29回日本認知症学会学術集会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-22700399
[Presentation] Effect of apolipoprotein E isofrom on formation and maintenance of blood-brain-barrier function2010
- Author(s)
  Kazuchika N, Hosono T, Nakamura T, Michikawa M
- Organizer
  Apo E symposium, Washington University
- Place of Presentation
  St.Louis
- Year and Date
  2010-06-07
- Data Source
  KAKENHI-PROJECT-21300145
[Presentation] The Sulf-degrading heparan sulfate epitope accumulates in cerebral amyloid ss plaques of mouse models and patients of Alzheimer's disease2010
- Author(s)
  Hosono T, Hossain M, Britschgi M, Akatsu H, van Kuppevelt T, Michikawa M, Wyss-Coray T, Uchimura K
- Organizer
  25th International Carbohydrate Symposium (ICS2010)
- Place of Presentation
  Makuhari
- Year and Date
  2010-08-02
- Data Source
  KAKENHI-PROJECT-21300145
[Presentation] ATBF1 interacts with amyloid precusor protein and enhances amyloidβ-protein production2010
- Author(s)
  Uhm KO, Horike H, Miura Y, Akatsu H, Michikawa M, Jung CG.
- Organizer
  The First International Conference on Neural Cell Culture(ICNCC 2010)
- Place of Presentation
  Seoul, Korea
- Year and Date
  2010-06-25
- Data Source
  KAKENHI-PROJECT-21300145
[Presentation] Apolipioprotein E and Alzheimer's disease2010
- Author(s)
  Michikawa M.
- Organizer
  Hallym University, The 12th Ilsong International Symposium, Hallym-Nagoya Academic Joint Meeting
- Place of Presentation
  Korea
- Year and Date
  2010-06-24
- Data Source
  KAKENHI-PROJECT-21300145
[Presentation] アポリポ蛋白Eとアルツハイマー病2010
- Author(s)
  道川誠
- Organizer
  教育講演:第18回中部老年期認知症研究会
- Place of Presentation
  名古屋
- Year and Date
  2010-10-30
- Data Source
  KAKENHI-PROJECT-21300145
[Presentation] Potent inhibition of ACE leads to Alzheimer-like pathology in APP transgenic mouse brain2010
- Author(s)
  Zou K, Liu S, Liu J, Tanabe C, Maeda T, Michikawa M, Komano H.
- Organizer
  International Conference on Alzheimer's Disease(ICAD)
- Place of Presentation
  Honolulu, Hawaii
- Year and Date
  2010-07-11
- Data Source
  KAKENHI-PROJECT-21300145
[Presentation] Apolipioprotein E and Alzheimer's disease Hallym University2010
- Author(s)
  Michikawa M.
- Organizer
  The 12th Ilsong International Symposium, Hallym-Nagoya Academic Joint Meeting
- Place of Presentation
  Hallym University, Gyeonggi-do, Korea
- Year and Date
  2010-06-24
- Data Source
  KAKENHI-PROJECT-21300145
[Presentation] Potent inhibition of ACE leads to Alzheimer-like pathology in APP transgenic mouse brain.2010
- Author(s)
  Kun Zou, Shuyu Liu, Junjun Liu, Chiaki Tanabe, Tomoji Maeda, Makoto Michikawa, Hiroto Komano.
- Organizer
  Alzheimer's Association International Conference on Alzheimer's Disease
- Place of Presentation
  Honolulu, Hawaii, USA
- Year and Date
  2010-07-11
- Data Source
  KAKENHI-PROJECT-22700399
[Presentation] レニンアギオテシ系とアルツハイマー病2010
- Author(s)
  道川誠
- Organizer
  慈恵医大神経疾患研究会
- Place of Presentation
  東京
- Year and Date
  2010-02-18
- Data Source
  KAKENHI-PROJECT-21300145
[Presentation] Potent inhibition of ACE leads to Alzheimer-like pathology in APP transgenic mouse brain2010
- Author(s)
  鄒鶤、劉殊余、劉俊俊、田邉千晶、前田智司、道川誠、駒野宏人
- Organizer
  2010年国際アルツハイマー病協会国際会議
- Place of Presentation
  ホノルル
- Data Source
  KAKENHI-PROJECT-22700399
[Presentation] Immunolocalization of the RB4CD12 anti-heparan sulfate epitope in the brain and its degradation by Sulfs, extracellular endosulfatases2010
- Author(s)
  Hossain M, Hosono T, Niimi S, van Kuppevelt T, Michikawa M, Rosen S, Uchimura K
- Organizer
  25th International Carbohydrate Symposium (ICS2010)
- Place of Presentation
  Makuhari
- Year and Date
  2010-08-05
- Data Source
  KAKENHI-PROJECT-21300145
[Presentation] アルツハイマー病モデルマウス大脳皮質に発現するヘパラン硫酸グリコサミノグリカンの構造解析2010
- Author(s)
  細野友美、新美しおり、ホサインモタラブ、菅谷典子、赤津裕康、トニーワイスコレイ、木全弘治、道川誠、内村健治
- Organizer
  第83回日本生化学会大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-21300145
[Presentation] ACE阻害によるアルツハイマー病モデルマウス脳内変化の解析2010
- Author(s)
  ゾウクン、劉俊俊、劉しゅ余、田邊千晶、前田智司、道川誠、駒野宏人
- Organizer
  Neuro2010
- Place of Presentation
  神戸
- Year and Date
  2010-09-02
- Data Source
  KAKENHI-PROJECT-21300145
[Presentation] Immunolocalization of the RB4CD12 Anti-Heparan Sulfate Epitopein Brain Microvessels and Its Degradation by Sulf-1 and Sulf-22010
- Author(s)
  Fukao-Hosono T, Hossain M, Ohtake-Niimi S, van Kuppevelt T, Michikawa M, Rosen S, Uchimura K.
- Organizer
  Annual meeting of Glycobiology
- Place of Presentation
  St.Pete Beach, USA
- Year and Date
  2010-11-08
- Data Source
  KAKENHI-PROJECT-21300145
[Presentation] ATBF1 interacts with amyloid precusor protein and enhances amyloid β-protein production2010
- Author(s)
  Uhm KO, Horike H, Miura Y, Akatsu H, Michikawa M, Jung CG.
- Organizer
  The First International Conference on Neural Cell Culture (ICNCC 2010)
- Place of Presentation
  Seoul, Korea
- Year and Date
  2010-06-25
- Data Source
  KAKENHI-PROJECT-21300145
[Presentation] APP代謝及びAb産生機構におけるホメオチィック因子AIBF1の機能解析2010
- Author(s)
  鄭且均、厳景玉、三浦裕、赤津裕康、道川誠
- Organizer
  Neuro2010
- Place of Presentation
  神戸
- Year and Date
  2010-09-03
- Data Source
  KAKENHI-PROJECT-21300145
[Presentation] Apolipoprotein E and Alzheimer's Disease2010
- Author(s)
  道川誠
- Organizer
  客員教授授与講演中国藩陽医学院・何氏視覚科学学院
- Place of Presentation
  藩陽,中国
- Year and Date
  2010-09-27
- Data Source
  KAKENHI-PROJECT-21300145
[Presentation] アルツハイマー病モデルマウス脳内に発現するヘパラン硫酸糖鎖の内部ドメイン構造の解析2010
- Author(s)
  細野友美、新美しおり、ホサインモタラブ、マーカスブリチギ、赤津裕康、菅谷典子、木全弘治、道川誠、トニーワイスコレイ、内村健治
- Organizer
  第29回日本認知症学会
- Place of Presentation
  名古屋
- Year and Date
  2010-11-05
- Data Source
  KAKENHI-PROJECT-21300145
[Presentation] Enhanced Alzheimer's-like pathology by ACE inhibition in APP transgenic mouse brain2010
- Author(s)
  ゾウクン、劉俊俊、劉しゅ余、田邊千晶、前田智司、道川誠、駒野宏人
- Organizer
  第29回日本認知症学会
- Place of Presentation
  名古屋
- Year and Date
  2010-11-05
- Data Source
  KAKENHI-PROJECT-21300145
[Presentation] ATBF1 interacts with amyloid precursor protein and enhancesamyloid b production.2010
- Author(s)
  Uhm KO, Horike H, Michikawa M, Jung CG
- Organizer
  International Conference on Alzheimer's Disease (ICAD)
- Place of Presentation
  Honolulu, Hawaii
- Year and Date
  2010-07-11
- Data Source
  KAKENHI-PROJECT-21300145
[Presentation] リポ蛋白質リパーゼは初代培養アストロサイトによるアミロイドbの取り込みを促進する2010
- Author(s)
  西辻和親、細野崇、内村健治、道川誠
- Organizer
  第29回日本認知症学会
- Place of Presentation
  名古屋
- Year and Date
  2010-11-05
- Data Source
  KAKENHI-PROJECT-21300145
[Presentation] TBF1 interacts with amyloid precursor protein and enhances amyloid b production2010
- Author(s)
  Uhm KO, Horike H, Michikawa M, Jung CG
- Organizer
  International Conference on Alzheimer's Disease(ICAD)
- Place of Presentation
  Honolulu, Hawaii
- Year and Date
  2010-07-11
- Data Source
  KAKENHI-PROJECT-21300145
[Presentation] 多価不飽和脂肪酸餌はLPSで誘導される脳内炎症を抑制する2010
- Author(s)
  細野崇、山内玲奈、紺谷昌仙、西辻和親、鄭且均、河島洋、木曽良信、道川誠
- Organizer
  第29回日本認知症学会
- Place of Presentation
  名古屋
- Year and Date
  2010-11-05
- Data Source
  KAKENHI-PROJECT-21300145
[Presentation] 脳内脂質代謝の生理学的ならびに病理学的意義について2009
- Author(s)
  道川誠
- Organizer
  日本膜学会シンポジウム
- Place of Presentation
  東京
- Year and Date
  2009-05-22
- Data Source
  KAKENHI-PROJECT-21300145
[Presentation] The cholesterol paradox in the pathogenesis of Alzheimer's disease.2009
- Author(s)
  道川誠
- Organizer
  第51回日本脂質生化学会シンポジウム
- Place of Presentation
  名古屋
- Year and Date
  2009-07-30
- Data Source
  KAKENHI-PROJECT-21300145
[Presentation] アルツハイマー病の予防・治療法開発の最前線2009
- Author(s)
  道川誠
- Organizer
  平成21年度日本大学生物資源科学部市民講座講演
- Place of Presentation
  藤沢
- Year and Date
  2009-07-04
- Data Source
  KAKENHI-PROJECT-21300145
[Presentation] アルツハイマー病の予防・治療法開発の最前線2009
- Author(s)
  道川誠
- Organizer
  平成21年度日本大学生物資源科学部市民講座講演
- Place of Presentation
  藤沢
- Year and Date
  2009-07-04
- Data Source
  KAKENHI-PROJECT-20023040
[Presentation] The role of ATBF1 in Alzheimer's disease2009
- Author(s)
  Jung CG, Kawaguchi M, Miura Y, Akatsu H, Hosono T, Uhm KO, Michikawa M.
- Organizer
  International Society for Neurochemistry(ISN)/Asia-Pacific Society for Neurochemistry(APSN)
- Place of Presentation
  Busan, Korea
- Year and Date
  2009-08-24
- Data Source
  KAKENHI-PROJECT-21300145
[Presentation] Aβenhances the ATBF1 expression responsible for the neuronal cell death2009
- Author(s)
  Jung CG, Kawaguchi M, Miura Y, Akatsu H, Hosono T, Uhm KO, Michikawa M.
- Organizer
  International conference on Alzheimer's disease(ICAD)
- Place of Presentation
  Vienna, Austria
- Data Source
  KAKENHI-PROJECT-21300145
[Presentation] The cholesterol paradox in the pathogenesis of Alzheimer's disease.2009
- Author(s)
  道川誠
- Organizer
  第51回日本脂質生化学会シンポジウム
- Place of Presentation
  名古屋
- Year and Date
  2009-07-30
- Data Source
  KAKENHI-PROJECT-20023040
[Presentation] レニンアンギオテン系とアミロイドβ蛋白代謝2009
- Author(s)
  道川誠
- Organizer
  第28回日本認知症学会シンポジウム
- Place of Presentation
  仙台
- Year and Date
  2009-11-21
- Data Source
  KAKENHI-PROJECT-20023040
[Presentation] 脳内脂質代謝の生理学的ならびに病理学的意義について2009
- Author(s)
  道川誠
- Organizer
  日本膜学会シンポジウム
- Place of Presentation
  東京
- Year and Date
  2009-05-22
- Data Source
  KAKENHI-PROJECT-20023040
[Presentation] Low activity of angiotensin-converting enzyme(ACE) is a risk factor for onset of Alzheimer's disease2009
- Author(s)
  Akatsu H, Matsuyama Z, Matsukawa N, Hori A, Yamamoto T, Michikawa M
- Organizer
  International conference on Alzheimer's disease(ICAD)
- Place of Presentation
  Vienna, Austria
- Data Source
  KAKENHI-PROJECT-21300145
[Presentation] Ab42-toAb40-and angiotensin-converting activities in different domains of angiotensin-converting enzyme2009
- Author(s)
  Zou K, Maeda T, Oba R, Michikawa M, Komano H.
- Organizer
  International conference on Alzheimer's disease(ICAD)
- Place of Presentation
  Vienna, Austria
- Data Source
  KAKENHI-PROJECT-21300145
[Presentation] The cholesterol paradox in the pathogenesis of Alzheimer's disease2009
- Author(s)
  道川誠
- Organizer
  第51回日本脂質生化学会
- Place of Presentation
  名古屋
- Year and Date
  2009-07-30
- Data Source
  KAKENHI-PROJECT-21300145
[Presentation] レニンアンギオテンシン系とアミロイドベータ蛋白代謝2009
- Author(s)
  道川誠
- Organizer
  第28回日本認知症学会シンポジウム
- Place of Presentation
  東北大学百周年記念会館,仙台
- Year and Date
  2009-11-21
- Data Source
  KAKENHI-PROJECT-21300145
[Presentation] Mechanism underlying apolipoprotein E(ApoE) isoform-dependent HDL generation and impairment of ApoE3-mediated HDL generation by homocysteine2009
- Author(s)
  Minagawa K, Gong J-S, Akatsu H. Jung C-G, Watanabe A, Nishitsuji K, Hosono T, Lund-Katz S, Phillips M C, Komano H, Saito H, and Michikawa M
- Organizer
  International conference on Alzheimer's disease(ICAD)
- Place of Presentation
  Vienna, Austria
- Data Source
  KAKENHI-PROJECT-21300145
[Presentation] Apolipoprotein E(1-272) fragment is associated with mitochondrial proteins and affects mitochondrial function in neuronal cells2009
- Author(s)
  Michikawa M, Nakamura T, Watanabe A, Hosono T, Fujino T.
- Organizer
  International Society for Neurochemistry(ISN)/Asia-Pacific Society for Neurochemistry(APSN)
- Place of Presentation
  Busan, Korea
- Year and Date
  2009-08-24
- Data Source
  KAKENHI-PROJECT-21300145
[Presentation] レニンアンギオテン系とアミロイドβ蛋白代謝2009
- Author(s)
  道川誠
- Organizer
  第28回日本認知症学会シンポジウム
- Place of Presentation
  仙台
- Year and Date
  2009-11-21
- Data Source
  KAKENHI-PROJECT-21300145
[Presentation] Inhibitory effect of homocysteine on ApoE3-mediated cholesterol efflux from cultured astrocytes2008
- Author(s)
  Minagawa H, Gong J-S, Lund-Katz S, Phillips M, Saito H, Michikawa M
- Organizer
  第51回日本神経化学会総会
- Place of Presentation
  富山
- Year and Date
  2008-09-12
- Data Source
  KAKENHI-PROJECT-20023040
[Presentation] Inhibitory effect of homocysteine on ApoE3-mediated cholesterol efflux from cultured astrocytes2008
- Author(s)
  Minagawa H, Gong J-S, Lund-Katz S, Phillips M, Saito H, Michikawa M
- Organizer
  第51回日本神経化学会総会
- Place of Presentation
  富山
- Year and Date
  2008-09-12
- Data Source
  KAKENHI-PROJECT-19300138
[Presentation] ホモシステインはApoE3によるHDL産生を阻害する2008
- Author(s)
  Minagawa H, Gong J-S, Lund-Katz S, Phillips M, Saito H, Michikawa M
- Organizer
  第27回日本認知症学会
- Place of Presentation
  前橋
- Year and Date
  2008-10-10
- Data Source
  KAKENHI-PROJECT-19300138
[Presentation] アルツハイマー病患者での血中Aβとアンギオテンシン変換酵素活性相関解析2008
- Author(s)
  赤津裕康, 小川倫弘, 兼坂岳志, 山本孝之, 道川誠
- Organizer
  第27回日本認知症学会
- Place of Presentation
  前橋
- Year and Date
  2008-10-10
- Data Source
  KAKENHI-PROJECT-19300138
[Presentation] ホモシステインはApoE3によるHDL産生を阻害する2008
- Author(s)
  Minagawa H, Gong J-S, Lund-Katz S, Phillips M, Saito H, Michikawa M
- Organizer
  第27回日本認知症学会
- Place of Presentation
  前橋
- Year and Date
  2008-10-10
- Data Source
  KAKENHI-PROJECT-20023040
[Presentation] 脂質代謝と神経変性疾患-その現状と未来への展望育成セミナー講義2008
- Author(s)
  道川誠
- Organizer
  第51回日本神経化学会総会
- Place of Presentation
  富山
- Year and Date
  2008-09-12
- Data Source
  KAKENHI-PROJECT-19300138
[Presentation] Presenilin regulates the maturation of membrane proteinsin opposite directins2008
- Author(s)
  Zou Kun, 細野崇、中村俊行、白石博久、前田智司、駒野宏人、道川誠
- Organizer
  第27回日本認知症学会
- Place of Presentation
  前橋
- Year and Date
  2008-10-10
- Data Source
  KAKENHI-PROJECT-20023040
[Presentation] アルツハイマー病の病態生理と治療戦略2008
- Author(s)
  道川誠
- Organizer
  名古屋市立大学大学院薬学研究科講義
- Place of Presentation
  名古屋市立大学
- Year and Date
  2008-06-25
- Data Source
  KAKENHI-PROJECT-19300138
[Presentation] Presenilin regulates the maturation of membrane proteinsin opposite directins2008
- Author(s)
  Zou Kun, 細野崇, 中村俊行, 白石博久, 前田智司, 駒野宏人, 道川誠
- Organizer
  第27回日本認知症学会
- Place of Presentation
  前橋
- Year and Date
  2008-10-10
- Data Source
  KAKENHI-PROJECT-19300138
[Presentation] Cholesterol Metabolism in the Central Nervous System and Alzheimer's Disease2008
- Author(s)
  Michikawa M.
- Organizer
  Pan-Pacific International Partnership Conference on Pharmaceutical and Life Sciences (The 4th US-Japan Joint Conference)
- Place of Presentation
  名古屋市立大学水野ホール, 名古屋
- Year and Date
  2008-02-23
- Data Source
  KAKENHI-PROJECT-19300138
[Presentation] Presenilin regulates the maturation of membrane2008
- Author(s)
  Zou Kun, 細野崇, 中村俊行, 白石博久, 前田智司, 駒野宏人, 道川誠
- Organizer
  第27回日本認知症学会
- Place of Presentation
  前橋
- Year and Date
  2008-10-10
- Data Source
  KAKENHI-PROJECT-19300138
[Presentation] 遺伝子多型で判断できるアルツハイマー病になりやすい人、なりにくい人2008
- Author(s)
  源川博久, 道川誠
- Organizer
  ゲノム広場2008 in 名古屋(主催 : 文部科学省科学研究費特定領域ゲノム4領域)
- Place of Presentation
  名古屋大学豊田講堂, 名古屋
- Data Source
  KAKENHI-PROJECT-19300138
[Presentation] Aβ代謝における脂質の意義-Cholesterol paradoxを紐解く一考察2008
- Author(s)
  道川誠
- Organizer
  第27回日本認知症学会、ワークショップII
- Place of Presentation
  前橋
- Year and Date
  2008-10-11
- Data Source
  KAKENHI-PROJECT-19300138
[Presentation] アルツハイマー病って何? -その予防と治療法開発の最前線-2008
- Author(s)
  道川誠
- Organizer
  あいち健康長寿産業クラスター形成事業国立長寿医療センター県民講座
- Place of Presentation
  東浦町
- Year and Date
  2008-12-02
- Data Source
  KAKENHI-PROJECT-19300138
[Presentation] Angiotensin-converting enzyme converts Aβ1-42 to Aβ1-40 and its inhibition enhances brain Aβ deposition.2007
- Author(s)
  K. Zou, H. Yamagucih, H. Akatsu T. Sakamoto, M. Ko, K. Mizoguchi, J.-S. Gong, W. Yu, T. Yamamoto, K. Kosaka, K. Yanagisawa, Michikawa M
- Organizer
  北米神経科学会
- Place of Presentation
  サンジエゴ、米国
- Year and Date
  2007-11-06
- Data Source
  KAKENHI-PROJECT-19300138
[Presentation] soform-dependnent effect of apolipoprotein E orcholesterol efflux2007
- Author(s)
  Minagawa H, Gong J-s, Nakamura T, Zou K, Lund-Katz S, Phillips M, Saito H, Michikawa M.
- Organizer
  日本神経化学会大会
- Place of Presentation
  横浜
- Year and Date
  2007-09-11
- Data Source
  KAKENHI-PROJECT-18023046
[Presentation] Mechanism underlying apolipoprotein e isoform-dependent lipid efflux from cultured neurons2007
- Author(s)
  Minagawa H. Watanabe A, Gong J.-S., Zou K, Nakamura T. Lind-Katz S. Phillips MC, Saito H, Michikawa M.
- Organizer
  北米神経科学会
- Place of Presentation
  サンジエゴ、米国
- Year and Date
  2007-11-06
- Data Source
  KAKENHI-PROJECT-19300138
[Presentation] Angiotensin-concerting enzyme converts Abetal-42 to Abetal-40 and its inhibition enhances brain Abeta deposition2007
- Author(s)
  Zou K, Yamaguchi H, Akatsu H, Sakamoto T, Ko M, Mizoguchi K, Gong JS, Yu W, Yamamoto T, Koska K, Komano H, Yanagisawa K, Michikawa M
- Organizer
  第30回日本分子生物学会年会および第80回日本生化学会大会、シンポジウム
- Place of Presentation
  横浜
- Year and Date
  2007-12-14
- Data Source
  KAKENHI-PROJECT-19300138
[Presentation] Apolipoprotein E-isoform-specific modulation of cholesterol metabolism in neurons2007
- Author(s)
  Michikawa M.
- Organizer
  日本神経化学会大会
- Place of Presentation
  横浜
- Year and Date
  2007-09-12
- Data Source
  KAKENHI-PROJECT-19300138
[Presentation] Transforming growth factor-betal associates with apoE-containing high-density lipoproteins : implications for neurodegeneration2007
- Author(s)
  Tesseur I. C. Huang Y, Corn GJ, Gong J.-S. Yanagisawa K. Michikawa M, Weisgraber, Wyss-Coray T.
- Organizer
  北米神経科学会
- Place of Presentation
  サンジエゴ、米国
- Year and Date
  2007-11-06
- Data Source
  KAKENHI-PROJECT-19300138
[Presentation] ER stress inducible protein, Herp, is involved in the degradation of the cofactor of gamma-secretase complex.2007
- Author(s)
  Marutani T, Maeda T, Kokame K, Zou K, Michikawa M, Komano H.
- Organizer
  第30回日本分子生物学会年会および第80回日本生化学会大会、シンポジウム
- Place of Presentation
  横浜
- Year and Date
  2007-12-13
- Data Source
  KAKENHI-PROJECT-19300138
[Presentation] Characterization of therapeutic antibody against Aβ oligomers for Alzheimer's disease2007
- Author(s)
  H. Sun, Y. Okamoto, T. Kawarabayashi, T. Yokoseki M. Shibata, M. Morishimas, Y. Saito, S. Murayama, Y. Ihara, M. Shoji M. M Michikawa, E. Matsubara
- Organizer
  北米神経科学会
- Place of Presentation
  サンジエゴ、米国
- Year and Date
  2007-11-05
- Data Source
  KAKENHI-PROJECT-19300138
[Presentation] Isoform-dependnent effect of apolipoprotein E on cholesterol efflux.2007
- Author(s)
  Minagawa H, Gong J-S, Nakamura T, Zou K, Lund-Katz S, Phillips M, Saito H, Michikawa M
- Organizer
  日本神経化学会大会
- Place of Presentation
  横浜
- Year and Date
  2007-09-11
- Data Source
  KAKENHI-PROJECT-19300138
[Presentation] 脳内コレステロール代謝制御とその破綻に起因する神経細胞障害2007
- Author(s)
  道川誠
- Organizer
  第30回日本分子生物学会年会および第80回日本生化学会大会、シンポジウム
- Place of Presentation
  横浜
- Year and Date
  2007-12-13
- Data Source
  KAKENHI-PROJECT-19300138
[Presentation] IApolipoprotein E-isoform-specific modulation of cholesterol metabolism in neurons2007
- Author(s)
  Michikawa M.
- Organizer
  日本神経化学会大会シンポジウム
- Place of Presentation
  横浜
- Year and Date
  2007-09-12
- Data Source
  KAKENHI-PROJECT-18023046
[Presentation] A ganglioside-induced soluble Abeta assembly causes neuronal death through NGF receptors2007
- Author(s)
  Yamamoto N, Matsubara E, Maeda S, Minagawa H, Takeshita A. Michikawa M, Yanagisawa K
- Organizer
  北米神経科学会
- Place of Presentation
  サンジエゴ、米国
- Year and Date
  2007-11-05
- Data Source
  KAKENHI-PROJECT-19300138
[Presentation] I Angiotensin-converting enzyme converts Aβ1-42 to Aβ1-40 and its inhibition enhances brain Aβ deposition2007
- Author(s)
  K. ZOU, H. YAMAGUCHI, H. AKATSU, T. SAKAMOTO, M. KO, K. MIZOGUCHI, J.-S. GONG, W. YU, T. YAMAMOTO, K. KOSAKA, K. YANAGISAWA, MICHIKAWA M
- Organizer
  北米神経科学会
- Place of Presentation
  サンヂィエゴ(アメリカ合衆国)
- Year and Date
  2007-11-06
- Data Source
  KAKENHI-PROJECT-18023046
[Presentation] アルツハイマー病の分子メカニズムと治療戦略
- Author(s)
  道川誠
- Organizer
  神経内科認知症研究会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-19300138

1. AKAGAWA Yasumasa (00127599)

# of Collaborated Projects: 4 results

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2. MIYAMOTO Yasunari (00555146)

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70. Shirono Miwa

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71. Yoshioka Hiroo

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72. SUGIYAMA YOSHITAKA

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73. TAKAMATSU YASUYUKI

# of Collaborated Projects: 1 results

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74. TAMAKOSHI KEIGO

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76. HAYASHI Hodeki

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# of Collaborated Products: 1 results

Michikawa Makoto 道川 誠

MICHIKAWA Makoto 道川 誠

道川 誠 ミチカワ マコト

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アルツハイマー病の早期診断を可能にする唾液バイオマーカーの開発Principal Investigator

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A study to elucidate mechanism, by which periodontists inducing memory impairment and to determine effect of its intervention on progression of dementia.Principal Investigator

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Study on mastication dysfunction-induced memory impairmentPrincipal Investigator

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Michikawa Makoto 道川誠

MICHIKAWA Makoto 道川誠

道川誠ミチカワマコト