MATSUDA Yasunobu 松田康伸

Researcher Number	40334669
Other IDs
Affiliation (Current)	2025: 新潟大学, 医歯学系, 准教授
Affiliation (based on the past Project Information) *help	2025: 新潟大学, 医歯学系, 准教授 2007 – 2023: Niigata University, Institute of Medicine and Dentistry, Associate Professor 2013: 新潟大学, 医歯学系, 准教授(Associate Professor) 2006: 新潟大学, 医歯学総合病院, 助手 2003: NIIGATA UNIVERSITY, Medical and Dental Hospital, Assistant, 医歯学総合病院, 助手 2002: 新潟大学, 医学部附属病院, 助手
Review Section/Research Field	Principal Investigator Gastroenterology / Basic Section 53010:Gastroenterology-related Except Principal Investigator Gastroenterology / Digestive surgery / Pediatric surgery / General surgery / Basic Section 55020:Digestive surgery-related / Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields / Applied pharmacology / Respiratory organ internal medicine / Basic Section 53010:Gastroenterology-related / Gastroenterology
Keywords	Principal Investigator エクソソーム / ゲムシタビン / 胆管がん / シスプラチン / 薬剤耐性 / 肝がん / 肝臓病学 / 胆道がん / 肝臓学 / 消化器内科 … More / drug resistance / hepatocellular carcinoma / sorafenib / TGF-beta / 分子標的薬 / ソラフェニブ / DNA二重鎖傷害 / 肝癌 / 移植・再生医療 … More Except Principal Investigator 肝移植 / mTOR / 肝細胞癌 / NK細胞 / 移植・再生医療 / 糖尿病 / 細胞移植 / 膵島移植 / 再生医療 / ラパマイシン / 脂質メディエーター / 移植免疫 / NQO1 / C型慢性肝炎 / インターフェロン / 肝癌 / 肝臓学 / 臓器移植 / 免疫寛容 / 免疫学 / 高次元データ解析システム / ゲノム / 高次元データ解析 / マイクロサテライト不安定性 / 腫瘍変異負荷 / ゲノム高次元データ解析 / 人工知能 / 深層学習 / 消化器癌 / セラミド / 移植外科学 / 薬物療法効果予測 / 肝臓外科学 / 薬物療法抵抗性 / 薬剤抵抗性 / 大腸癌肝転移 / 人工バイオ肝臓 / 脱落歯 / 薬剤スクリーニング / 動物モデル / 重症肝障害 / 歯髄バンク / テーラーメード医療 / 薬剤毒性スクリーニング / 歯髄幹細胞 / ヒトDNA特異的PCR / 劇症肝炎 / テーラーメイド医療 / ヒト細胞特異的PCR / 歯の細胞バンク / 肝細胞 / 間葉系幹細胞 / 歯髄細胞 / 脂肪肝 / 肝線維化 / M2BPGi / フィブロスキャン / 肝障害 / NASH / NAFLD / 持続的陽圧呼吸療法 / 低酸素血症 / 持続陽圧呼吸療法 / 非アルコール性脂肪肝炎 / CPAP / 夜間低酸素血症 / 睡眠時無呼吸症候群 / 非アルコール性脂肪性肝疾患 / 先制医療 / 消化器発癌 / 免疫監視不全 / 免疫老化 / 自然修復 / 気管修復 / Vimentin / PCNA / 修復調節 / 気管 / サンドスタチン / インフリキシマブ / サイトカイン / 組織修復 / 家兎 / 肉芽形成 / ソマトスタチン / 治癒機構 / 上皮再生 / 肉芽 / ソマトスタチンアナログ / 創傷治癒 / 気管再生 / 気管欠損 / 小児腫瘍学 / 小児外科学 / 外科系臨床医学 / 医歯薬学 / ｍTOR / 小児 / 肝芽腫 / 転移能 / 膵癌 / 胆道癌 / 細胞増殖能 / B/6系マウス / CRISPR/Cas9 / リンパ管浸潤 / 細胞外基質 / リンパ管新生 / ダブルノックアウトマウス / 膵臓外科学 / 胆道外科学 / 液性免疫 / 自然リンパ球 / chronic hepatitis C / natural killer cells / liver transplantation / transplantation immunology / 臨床 / ナチュラルキラー細胞 / Cell therapy / Liver transplantation / Immunological tolerance / Regulatory T cells / 細胞移入療法 / 免疫制御性T細胞 / p62 / Keap1 / Nrf2 / KRAS / 抗癌剤耐性 / 大腸癌 / 肝脂肪化 / RBP4 / リバビリン / Insulin抵抗性 / IFN / インスリン抵抗性 / Peg-IFN / RBP-4 / HCV / metallic / granulation / tracheal defect / coil / tracheal substitute / trachea / rapamycin / DNA二重鎖切断 / γ-H2AX / 上皮内癌 / DNA損傷修復機構 / field carcinogenesis / p53-binding protein 1 / 表層拡大進展 / 胆管癌 / 早期DNA損傷修復機構 / 免疫監視 / トランスジェニックマウス / ATM / HBx遺伝子 / DNA修復機構 / ウイルス発癌 / DNA修復 / 発癌予防 / IFNβ / 分子機序 / 発がん抑制 / 細胞内局在 / p21 / HBV / C型肝炎 / C型肝肝炎 / 内視鏡的治療 / RNA干渉 / 消化管狭窄 / 糖鎖 / 内視鏡 / RNAi / siRNA / 線維化 / クローン病 / 炎症性腸疾患 / shear stress / 調節性T細胞 / ドナー特異的抗原門脈内投与 / 拒絶反応 / 移植 / 肝幹細胞 / ドナー特異的抗原 / 外科 Less

肝がんp90RSK含有エクソソームに着目したマルチキナーゼ阻害剤耐性の克服Principal Investigator
- Principal Investigator
  
  松田康伸
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Niigata University
胆管がん腫瘍再増殖の予防法確立を目指したエクソソーム蛋白活性化機構の解析Principal Investigator
- Principal Investigator
  
  松田康伸
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Niigata University
Development of Artificial Intelligence by Deep Learning Based on Genomic High-Dimensional Data Analysis System for Gastrointestinal Cancer
- Principal Investigator
  
  WAKAI TOSHIFUMI
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Niigata University
Extend islet graft survival in pancreatic islet transplantation by applying the immunoregulatory mechanism of ceramide
- Principal Investigator
  
  Kobayashi Takashi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  Niigata University
Molecular analysis of the drug resistance mediated by exosomes in biliary tract cancerPrincipal Investigator
- Principal Investigator
  
  MATSUDA YASUNOBU
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Niigata University
消化器発癌における免疫老化による免疫監視不全の関与の解明と新規先制医療の開発
- Principal Investigator
  
  山際訓
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Niigata University
Regenetative medicine using decidouous teeth preparing for future diseases
- Principal Investigator
  
  Shogo Ohkoshi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  The Nippon Dental University
Elucidation of clinical significance and chemotherapy resistance mechanism of NAD(P)H:quinone oxidoreductase 1 (NQO1) expression for colorectal liver metastasis
- Principal Investigator
  
  Nakano Mae
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Niigata University
Creation of next-generation cell therapy for diabetes with focus on nesidioblastic change
- Principal Investigator
  
  Kobayashi Takashi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  Niigata University
The mechanism of exosome-mediated drug resistance in hepatoma cellsPrincipal Investigator
- Principal Investigator
  
  Yasunobu MATSUDA
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Niigata University
Elucidation of the signal expression mechanism in the mTOR cell and development of the rapamycin treatment in the hepatoblastoma
- Principal Investigator
  
  Arai Yuhki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatric surgery
- Research Institution
  Niigata University
Histochemical analysis and modification of the natural healing process of the large defect of rabbit trachea.
- Principal Investigator
  
  Kubota Masayuki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatric surgery
- Research Institution
  Niigata University
Establishment of new treatment strategy for NASH by elucidating the mechanisms of fibrosis progression due to nocturnal intermittent hypoxia.
- Principal Investigator
  
  HIRONO Haruka
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  The Nippon Dental University
肝内免疫監視不全の回復と抗体関連型拒絶反応を応用した肝癌に対する新規治療法の開発
- Principal Investigator
  
  山際訓
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Niigata University
Elucidation of molecular mechanism of lipid mediator involved in metastatic ability of biliary tract cancer / pancreatic cancer and clinical application
- Principal Investigator
  
  WAKAI TOSHIFUMI
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Niigata University
Elucidation of the mechanism of drug resistance in colorectal cancer by p62-Keap 1-Nrf2 pathway
- Principal Investigator
  
  KAMEYAMA Hitoshi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Niigata University
Discovery of new insulin-resistance marker which determines the effect of IFN for chronic hepatitis C
- Principal Investigator
  
  Ohkoshi Shogo
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  The Nippon Dental University
  Showa University
Molecular Analysis of Cytokine-mediated Sorafenib ResistancePrincipal Investigator
- Principal Investigator
  
  MATSUDA YASUNOBU
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Niigata University
Importance of NK cell function in the mechanisms responsible for tumor evasion of immune surveillance against hepatocellular carcinoma after liver transplantation
- Principal Investigator
  
  YAMAGIWA Satoshi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Niigata University
Early DNA damage response in residual carcinoma in situ at ductal stumps and local recurrence in patients undergoing resection for extrahepatic cholangiocarcinoma
- Principal Investigator
  
  WAKAI Toshifumi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Niigata University
Effects of rapamycin on granulation formation in response to centrally-doubled coiled stents as a tracheal substitute.
- Principal Investigator
  
  KUBOTA Masayuki
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Pediatric surgery
- Research Institution
  Niigata University
Development of new IFN-strategy that based on DNA repair mechanism
- Principal Investigator
  
  OHKOSHI Shogo
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Showa University
  Niigata University
Development of New Strategy of Immunological Tolerance Inductionby Intraportal administration of donor specific Mesenchymal hepatic stem cell in OrganTransplantation
- Principal Investigator
  
  SATO Yoshinobu
- Project Period (FY)
  2009 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  Niigata University
Development of a new endoscopic therapy using RNAi for intestinal fibrosis of Crohn's disease
- Principal Investigator
  
  SUZUKI Kenji
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Niigata University
Importance of NK cells and intrahepatic immune responses for the acceleration of hepatitis C after liver transplantation
- Principal Investigator
  
  YAMAGIWA Satoshi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Niigata University
Prospective analysis of DNA damage and repair markers in the patients with high risk of hepatocellular cancerPrincipal Investigator
- Principal Investigator
  
  MATSUDA Yasunobu
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Niigata University
Manipulating the stromal-derived factor 1 function in mouse liver cirrhosisPrincipal Investigator
- Principal Investigator
  
  MATSUDA Yasunobu
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Niigata University
Analysis of the innate immune responses in the liver of patients with chronic hepatitis C following liver transplantation to develop a novel immunotherapy for the recurrent hepatitis C infection
- Principal Investigator
  
  YAMAGIWA Satoshi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Niigata University
Development of a new cell therapy by adoptive transfer of regulatory T cells to induce immunological tolerance for the transplanted liver
- Principal Investigator
  
  ICHIDA Takafumi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  NIIGATA UNIVERSITY

[Book] Molecular mechanism of DNA damage response pathway during hepatic carcinogenesis(Hepatocellular Carcinoma/Book 1)
- Author(s)
  Matsuda Y, Wakai T
- Publisher
  (in press)
- Data Source
  KAKENHI-PROJECT-21590835
[Journal Article] Exosomal p38 Mitogen-activated Protein Kinase Promotes Tumour Repopulation in TP53-mutated Bile Duct Cancer Cells2022
- Author(s)
  大澤まみ、松田康伸、坂田純、若井俊文
- Journal Title
  
  Anticancer Res
  
  Volume: 42 Issue: 2 Pages: 745-757
- DOI
  10.21873/anticanres.15533
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08365, KAKENHI-PROJECT-21H02998
[Journal Article] Urokinase-type Plasminogen Activator Is a Therapeutic Target for Overcoming Sorafenib Resistance in Hepatoma Cells2021
- Author(s)
  Osawa M, Matsuda Y, Kinoshita Y, Wakai T
- Journal Title
  
  Anticancer Res
  
  Volume: 41 Issue: 2 Pages: 645-660
- DOI
  10.21873/anticanres.14816
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02998
[Journal Article] 肝癌薬剤耐性におけるエクソソームの有用性および課題2019
- Author(s)
  松田康伸、寺井崇二
- Journal Title
  
  BIO Clinica
  
  Volume: 34 Pages: 737-740
- Data Source
  KAKENHI-PROJECT-19K08365
[Journal Article] Clinical significance of NQO1 expression in patients with advanced KRAS wild colorectal cancer2017
- Author(s)
  Hitoshi Kameyama, Yuki Hirose, Yasunobu Matsuda, Masayuki Nagahashi, Hiroshi Ichikawa, You Sato, Saki Yamada, Shinnosuke Hotta, Yosuke Tajima, Takuma Okamura, Mae Nakano, Masato Nakano, Yoshifumi Shimada, Jun Sakata, Takashi Kobayashi, Toshifumi Wakai
- Journal Title
  
  Int J Clin Exp Pathol
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462006
[Journal Article] 肝癌薬剤耐性におけるエクソソームの有用性および課題2017
- Author(s)
  松田康伸、寺井崇二
- Journal Title
  
  Medical Science Digest
  
  Volume: 43(7) Pages: 12-15
- Data Source
  KAKENHI-PROJECT-16K09347
[Journal Article] Retinol binding protein 4, an insulin-resistance marker, induces interferon resistance in chronic hepatitis C.2016
- Author(s)
  Takahashi H, Ohkoshi S, Matsuda Y, et al.
- Journal Title
  
  Hepatogastroenterology
  
  Volume: 未定
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25461012
[Journal Article] Comparison of Number Versus Ratio of Positive Lymph Nodes in the Assessment of Lymph Node Status in Extrahepatic Cholangiocarcinoma2016
- Author(s)
  Sakata J, Wakai T, Matsuda Y, Ohashi T, Hirose Y, Ichikawa H, Kobayashi T, Minagawa M, Kosugi S, Koyama Y, Akazawa K, Ajioka Y
- Journal Title
  
  Ann Surg Oncol
  
  Volume: 23 Issue: 1 Pages: 225-234
- DOI
  10.1245/s10434-015-4609-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04927
[Journal Article] DNA damage response and sphingolipid signaling in liver diseases2016
- Author(s)
  Nagahashi M, Matsuda Y, Moro K, Tsuchida J, Soma D, Hirose Y, Kobayashi T, Kosugi SI, Takabe K, Komatsu M, Wakai T
- Journal Title
  
  Surg Today
  
  Volume: 印刷中 Issue: 9 Pages: 995-1005
- DOI
  10.1007/s00595-015-1270-8
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04927, KAKENHI-PROJECT-15K15471, KAKENHI-PROJECT-16K15610
[Journal Article] Oncogenic role of p21 in hepatocarcinogenesis suggests a new treatment strategy2015
- Author(s)
  Ohkoshi S, Yano M, Matsuda Y.
- Journal Title
  
  World J Gastroenterol
  
  Volume: 21 Issue: 42 Pages: 12150-6
- DOI
  10.3748/wjg.v21.i42.12150
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25461012
[Journal Article] Retinol binding protein 4, an insulin- resistance marker, induces interferon resistance in chronic hepatitis C2015
- Author(s)
  Hiromichi Takahashi, Shogo Ohkoshi, Masahiko Yano, Satoshi Yamagiwa, Masanori Ikeda, Nobuyuki Kato, Yasunobu Matsuda, Yutaka Aoyagi
- Journal Title
  
  Hepatogastroenterology
  
  Volume: In Press
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25461012
[Journal Article] Hepatitis B virus X stimulates redox signaling through activation of ataxia telangiectasia mutated kinase2014
- Author(s)
  Matsuda, Y. Sanpei A, Wakai T, Kubota M, Osawa M, Hirose Y, Sakata J, Kobayashi T, Fujimaki S, Takamura M, Yamagiwa S, Yano M, Ohkoshi S, Aoyagi Y
- Journal Title
  
  Int J Clin Exp Pathol
  
  Volume: 7 Pages: 2032-2043
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659773
[Journal Article] Valproic acid overcomes transforming growth factor-β-mediated sorafenib resistance in hepatocellular carcinoma2014
- Author(s)
  Yasunobu Matsuda, Toshifumi Wakai, Masayuki Kubota, Mami Osawa, Yuki Hirose, Jun Sakata, Takashi Kobayashi, Shun Fujimaki, Masaaki Takamura, Satoshi Yamagiwa, Yutaka Aoyagi
- Journal Title
  
  International Journal of Clinical & Experimental Pathology
  
  Volume: 7(4) Pages: 1299-1313
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590962
[Journal Article] Valproic acid overcomes transforming growth factor-β-mediated sorafenib resistance in hepatocellular carcinoma.2014
- Author(s)
  Matsuda Y, Wakai T, Kubota M, Osawa M, Hirose Y, Sakata J, Kobayashi T, Fujimaki S, Takamura M, Yamagiwa S, Aoyagi Y.
- Journal Title
  
  Int J Clin Exp Pathol
  
  Volume: 7 (4) Pages: 1299-1313
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590962
[Journal Article] Hepatitis B virus X stimulates redox signaling through activation of ataxia telangiectasia mutated kinase.2014
- Author(s)
  Matsuda Y, Sanpei A, Wakai T, Kubota M, Osawa M, Hirose Y, Sakata J, Kobayashi T, Fujimaki S, Takamura M, Yamagiwa S, Yano M, Ohkoshi S, Aoyagi Y
- Journal Title
  
  Int J Clin Exp Pathol
  
  Volume: 7 Pages: 2032-43
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25461012
[Journal Article] Valproic acid overcomes transforming growth factor-beta-mediated sorafenib resistance in hepatocellular carcinoma2014
- Author(s)
  Matsuda Y, Wakai T, Kubota M, Osawa M, Hirose Y, Sakata J, Kobayashi T, Fujimaki S, Takamura M, Yamagiwa S, Aoyagi Y.
- Journal Title
  
  Int J Clin Exp Pathol
  
  Volume: 7 Pages: 1299-1313
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659773
[Journal Article] Hepatitis B virus X induces cell proliferation in the hepatocarcinogenesis via up-regulation of cytoplasmic p21 expression2013
- Author(s)
  Yano M, Ohkoshi S, Aoki YH, Takahashi H, Kurita S, Yamazaki K, Suzuki K, Yamagiwa S, Sanpei A, Fujimaki S, Wakai T, Kudo SE, Matsuda Y,Aoyagi Y
- Journal Title
  
  Liver Int
- Data Source
  KAKENHI-PROJECT-22590722
[Journal Article] Mycotoxins are onventional and novel risk biomarkers for hepatocellular carcinoma2013
- Author(s)
  Matsuda Y, Wakai T, Kubota M, Osawa M, Sanpei A, Fujimaki S
- Journal Title
  
  World J Gastroenterol
  
  Volume: 19 Issue: 17 Pages: 2587-2590
- DOI
  10.3748/wjg.v19.i17.2587
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659773
[Journal Article] P21-activated kinase-2 is a critical mediator of transforming growth factor-b-induced hepatoma cell migration.2013
- Author(s)
  Sato M, Matsuda Y, Wakai T, Kubota M, Osawa M, Fujimaki S, Sanpei A, Takamura M, Yamagiwa S, Aoyagi Y
- Journal Title
  
  J Gastroenterol Hepatol
  
  Volume: 28 Issue: 6 Pages: 1047-1055
- DOI
  10.1111/jgh.12150
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659773
[Journal Article] Risk of subsequent biliary malignancy in patients undergoing cyst excision for congenital choledochal cysts.2013
- Author(s)
  Ohashi T, Wakai T, Kubota M, Matsuda Y, Arai Y, Ohyama T, Nakaya K, Okuyama N, Sakata J, Shirai Y, Ajioka Y
- Journal Title
  
  J Gastroenterol Hepatol
  
  Volume: 28 Issue: 2 Pages: 243-247
- DOI
  10.1111/j.1440-1746.2012.07260.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592693, KAKENHI-PROJECT-24659773
[Journal Article] Clinical significance of cell cycle inhibitors in hepatocellular carcinoma.2013
- Author(s)
  Matsuda Y, Wakai T, Kubota M, Takamura M, Aoyagi Y, Osawa M, Fujimaki S, Sanopei A, Genda T, Ichida T
- Journal Title
  
  Med Mod Morphol
  
  Volume: 46 Issue: 4 Pages: 185-192
- DOI
  10.1007/s00795-013-0047-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659773
[Journal Article] Hepatitis B virus X induces cell proliferation in the hepatocarcinogenesis2013
- Author(s)
  Yano M
- Journal Title
  
  Liv Int
  
  Volume: in press Issue: 8 Pages: 2018-2029
- DOI
  10.1111/liv.12176
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590722, KAKENHI-PROJECT-25461012
[Journal Article] Effects of rapamycin on granulation formation in response to centrally-doubled coiled stents as a tracheal substitute.2013
- Author(s)
  Kubota M, Matsuda Y, Fujimaki S, Osawa M, Wakai T, Nakaya K
- Journal Title
  
  J Pediatr Surg
  
  Volume: 48 Issue: 12 Pages: 2416-2424
- DOI
  10.1016/j.jpedsurg.2013.08.013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592693, KAKENHI-PROJECT-24659773
[Journal Article] Blockade of ataxia telangiectasia mutated sensitizes hepatoma cell lines to sorafenib by interfering with Akt signaling2012
- Author(s)
  Fujimaki S, Matsuda Y, Wakai T, Sanpei A, Kubota M, Takamura M, Yamagiwa S, Yano M, Ohkoshi S, Aoyagi Y
- Journal Title
  
  Cancer Lett
  
  Volume: 319(1) Pages: 98-108
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590834
[Journal Article] Reduced NKG2D ligand expression in hepatocellular carcinoma correlates with early recurrence2012
- Author(s)
  Kamimura H, Yamagiwa S, Tsuchiya A, Takamura M, Matsuda Y, Ohkoshi S, Inoue M, Wakai T, Shirai Y, Nomoto M, Aoyagi Y
- Journal Title
  
  J. Hepatol
  
  Volume: 56(2) Pages: 381-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590834
[Journal Article] Blockade of ataxia telangiectasia mutated sensitizes hepatoma cell lines to sorafenib by interfering with Akt signaling2012
- Author(s)
  Fujimaki S
- Journal Title
  
  Cancer Lett.
  
  Volume: 319 Issue: 1 Pages: 98-108
- DOI
  10.1016/j.canlet.2011.12.043
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390205, KAKENHI-PROJECT-21590834, KAKENHI-PROJECT-22590722, KAKENHI-PROJECT-23659395
[Journal Article] Blockade of ataxia telangiectasia mutated sensitizes hepatoma cell lines to sorafenib by interfering with Akt signaling.2012
- Author(s)
  Fujimaki S, Matsuda Y, Wakai T, Sanpei A, Kubota M, Takamura M, Yamagiwa S, Yano M, Ohkoshi S, Aoyagi Y.
- Journal Title
  
  Cancer lett
  
  Volume: 319 Issue: 1 Pages: 98-108
- DOI
  10.1155/2013/597095
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590962
[Journal Article] Blockade of ataxia telangiectasia mutated sensitizes hepatoma eell lines to sorafenib by interfering with Akt signaling2012
- Author(s)
  Fujimaki S, Matsuda Y, Ohkoshi S, et al
- Journal Title
  
  Cancer Lett
  
  Volume: 319 Pages: 98-108
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590722
[Journal Article] Blockade of ataxia telangiectasia mutated sensitizes hepatoma cell lines to sorafenib by interfering with Akt signaling2012
- Author(s)
  Fujimaki S, Matsuda Y, Wakai T, Sanpei A, Kubota M, Takamura M, Yamagiwa S, Yano M, Ohkoshi S, Aoyagi Y
- Journal Title
  
  Cancer Lett
  
  Volume: 319(1) Pages: 98-108
- Data Source
  KAKENHI-PROJECT-22590722
[Journal Article] Multicentric occurrence of hepatocellular carcinoma with nonalcoholic steatohepatitis2011
- Author(s)
  Kawai H, Nomoto M, Suda T, Kamimura K, Tsuchiya A, Tamura Y, Yano M, Takamura M, Igarashi M, Wakai T, Yamagiwa S, Matsuda Y, Ohkoshi S, Kurosaki I, Shirai Y, Okada M, Aoyagi Y
- Journal Title
  
  World J. Hepatol
  
  Volume: 3(1) Pages: 15-23
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590834
[Journal Article] Multicentric occurrence of hepatocellular carcinoma with nonalcoholic steatohepatitis2011
- Author(s)
  Kawai H, Nomoto M, Suda T, Kamimura K, Tsuchiya A, Tamura Y, Yano M, Takamura M, Igarashi M, Wakai T, Yamagiwa S, Matsuda Y, Ohkoshi S, Kurosaki I, Shirai Y, Okada M, Aoyagi Y
- Journal Title
  
  World J Hepatol
  
  Volume: 3(1) Pages: 15-23
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590835
[Journal Article] Prognostic significance of NQO1 expression in intrahepatic cholangiocarcinoma2011
- Author(s)
  Wakai T, Shirai Y, Sakata J, Matsuda Y, Korita PV, Takamura M, Ajioka Y, Hatakeyama K
- Journal Title
  
  Int J Clin Exp Pathol
  
  Volume: 4(4) Pages: 363-370
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590835
[Journal Article] Characterization of elevated alanine aminotransferase levels during pegylated-interferonα-2b plus ribavirin treatment for chronic hepatitis C2011
- Author(s)
  Aoki YH, Ohkoshi S, Yamagiwa S, Yano M, Takahashi H, Waguri N, Igarashi K, Sugitani S, Takahashi T, Ishikawa T, Kamimura T, Wakabayashi H, Watanabe T, Matsuda Y, Nomoto M, Aoyagi Y
- Journal Title
  
  Hepatol Res
  
  Volume: 41(2) Pages: 118-125
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590835
[Journal Article] Multicentric occurrence of hepatocellular carcinoma with nonalcoholic steatohepatitis2011
- Author(s)
  Kawai H, Nomoto M, Suda T, Kamimura K, Tsuchiya A, Tamura Y, Yano M, Takamura M, Igarashi M, Wakai T, Yamagiwa S, Matsuda Y, Ohkoshi S, (4)Kurosaki I, Shirai Y, Okada M, Aoyagi Y
- Journal Title
  
  World J Hepatol
  
  Volume: 3(1) Pages: 15-23
- Data Source
  KAKENHI-PROJECT-22590722
[Journal Article] Failure to achieve 2-log10 viral decrease in first four weeks of peg-IFNalpha-2b plus ribavirin therapy for chronic hepatitis C with genotype 1b and high viral titer is useful in predicting non-response : evaluation of response-guided therapy2011
- Author(s)
  Ohkoshi S, Yamagiwa S, Yano M, Takahashi H, Aoki YH, Waguri N, Igarashi K, Sugitani S, Takahashi T, Ishikawa T, Kamimura T, Wakabayashi H, Watanabe T, Matsuda Y, Aoyagi Y
- Journal Title
  
  Hepatogastroenterology
  
  Volume: 58(107-108) Pages: 965-70
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590834
[Journal Article] Hepatocellular carcinoma and liver transplantation : clinical perspective on molecular targeted strategies2011
- Author(s)
  Matsuda Y, Ichida T, Fukumoto M
- Journal Title
  
  Med Mol Morphol
  
  Volume: 44(3) Pages: 117-124
- NAID
  10030463626
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590835
[Journal Article] Hepatocellular carcinoma and liver transplantation : clinical perspective on molecular targeted strategies2011
- Author(s)
  松田康伸、市田隆文
- Journal Title
  
  Med Mol Morphol
  
  Volume: 44 Issue: 3 Pages: 117-124
- DOI
  10.1007/s00795-011-0547-2
- NAID
  10030463626
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590835
[Journal Article] Alteration of p53-binding protein 1 expression as a risk factor for local recurrence in patients undergoing resection for extrahepatic cholangiocarcinoma2011
- Author(s)
  若井俊文、松田康伸, 他8名
- Journal Title
  
  Int J Oncol
  
  Volume: 38 Issue: 5 Pages: 1227-1236
- DOI
  10.3892/ijo.2011.959
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590835, KAKENHI-PROJECT-21591768, KAKENHI-PROJECT-23590391
[Journal Article] Sorafenib : complexities of Raf-dependent and-independent signaling are now unveiled2011
- Author(s)
  松田康伸、福本学
- Journal Title
  
  Med Mol Morphol
  
  Volume: 44 Issue: 4 Pages: 183-189
- DOI
  10.1007/s00795-011-0558-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590835
[Journal Article] Failure to achieve 2-log10 viral decrease in first four weeks of peg-IFNalpha-2b plus ribavirin therapy for chronic hepatitis C with genotype 1b and high viral titer is useful in predicting non-response: evaluation of response-guided therapy2011
- Author(s)
  Ohkoshi S, Yamagiwa S, Yano M, Takahashi H, Aoki YH, Waguri N, Igarashi K, Sugitani S, Takahashi T, Ishikawa T, Kamimura T, Wakabayashi H, Watanabe T, Matsuda Y,Aoyagi Y.
- Journal Title
  
  Hepatogastroenterology
  
  Volume: 58(107-108) Pages: 965-70
- Data Source
  KAKENHI-PROJECT-22590722
[Journal Article] Characterization of elevated alanine aminotransferase levels during pegylated-interferon α-2b plus ribavirin treatment for chronic hepatitis C2011
- Author(s)
  Aoki YH, Ohkoshi S, Yamagiwa S, Yano M, Takahashi H, Waguri N, Igarashi K, Sugitani S, Takahashi T, Ishikawa T, Kamimura T, Wakabayashi H, Watanabe T, Matsuda Y,(2)Nomoto M, Aoyagi Y
- Journal Title
  
  Hepatol Res
  
  Volume: 41(2) Pages: 118-25
- Data Source
  KAKENHI-PROJECT-22590722
[Journal Article] Alteration of p53-binding protein 1 expression as a risk factor for local recurrence in patients undergoing resection for extrahepatic cholangiocarcinoma2011
- Author(s)
  Wakai T, Shirai Y, Sakata J, Korita PV, Matsuda Y, Takamura M, Ohashi R, Nagahashi M, Ajioka Y, Hatakeyama K
- Journal Title
  
  Int J Oncol
  
  Volume: 38(5) Pages: 1227-1236
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590835
[Journal Article] A case with chronic hepatitis C who developed liver cirrhosis due to liver dysfunction caused by pegylated interferon plus ribavirin treatment despite negativity of serum HCV RNA, during therapy2011
- Author(s)
  Ohkoshi S, Morita S, Tanaka Y, Yano M, Takeuchi M, Takahashi H, Ikeda H, Yamagiwa S, Matsuda Y, Nomoto M, Aoyagi Y
- Journal Title
  
  Nihon Shokakibyo Gakkai Zasshi
  
  Volume: 108(2) Pages: 267-74
- NAID
  10029388211
- Data Source
  KAKENHI-PROJECT-22590722
[Journal Article] Characterization of elevated alanine aminotransferase levels during pegylated-interferonα-2b plus ribavirin treatment for chronic hepatitis C2011
- Author(s)
  Aoki YH, Ohkoshi S, Yamagiwa S, Yano M, Takahashi H, Waguri N, Igarashi K, Sugitani S, Takahashi T, Ishikawa T, Kamimura T, Wakabayashi H, Watanabe T, Matsuda Y, Nomoto M, Aoyagi Y
- Journal Title
  
  Hepatol. Res
  
  Volume: 41(2) Pages: 118-25
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590834
[Journal Article] Multidmg resistanoe-associated protein 2 determines the of efficacy of Cisplatin in patients with hepatocellular carcinoma.2010
- Author(s)
  コリタ・プラベル, 若井俊文, 白井良夫, 松田康伸, 他7名
- Journal Title
  
  Oncology Reports
  
  Volume: vol.23 Pages: 965-972
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590835
[Journal Article] Very-Low-Dose Pegylated Interferon a2a Plus Ribavirin Therapy for Advanced Liver Cirrhosis Type C : A Possible Therapeutic Alternative without Splenic Intervention2010
- Author(s)
  Ohkoshi S, Yamagiwa S, Yano M, Takahashi H, Aoki YH, Matsuda Y, Aoyagi Y
- Journal Title
  
  Case Rep. Gastroenterol
  
  Volume: 4(2) Pages: 261-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590834
[Journal Article] Very-Low-Dose Pegylated Interferon a2a Plus Ribavirin Therapy for Advanced Liver Cirrhosis Type C : A Possible Therapeutic Alternative without Splenic Intervention2010
- Author(s)
  Ohkoshi S, Yamagiwa S, Yano M, Takahashi H, Aoki YH, Matsuda Y, Aoyagi Y
- Journal Title
  
  Case Rep Gastroenterol
  
  Volume: 4(2) Pages: 261-266
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590835
[Journal Article] Loss of liver-intestine cadherin in human intrahepatic cholangiocarcinoma promotes angiogenesis by up-regulating metal-responsive transcription factor-1 and placental growth factor2010
- Author(s)
  Takamura M, Yamagiwa S, Wakai T, Tamura Y, Kamimura H, Kato T, Tsuchiya A, Matsuda Y, Shirai Y, Ichida T, Ajioka Y, Aoyagi Y
- Journal Title
  
  Int. J. Oncol
  
  Volume: 36(1) Pages: 245-54
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590834
[Journal Article] Loss of liver-intestine cadherin in human intrahepatic cholangiocarcinoma promotes angiogenesis by upregulating metal-responsive transcription factor-1 and placental growth factor2010
- Author(s)
  Takamura M, Yamagiwa S, Wakai T, Tamura Y, Kamimura H, Kato T, Tsuchiya A, Matsuda Y, Shirai Y, Ichida T, Ajioka Y, Aoyagi Y
- Journal Title
  
  Int J Oncol
  
  Volume: 36(1) Pages: 245-254
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590835
[Journal Article] MRP2 determines the efficacy of cisplatin in patients with hepatocellular carcinoma2010
- Author(s)
  Korita PV, Wakai T, Shirai Y, Matsuda Y, Sakata J, Takamura M, Yano M, Sanpei A, Aoyagi Y, Hatakeyama K, Ajioka Y
- Journal Title
  
  Oncol Rep
  
  Volume: 23(4) Pages: 965-972
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590835
[Journal Article] Clinicopathological analysis of CD133(+) and NCAM(+) humanhepatic stem/progenitor cells in damagedlivers and hepatocellular carcinomas2009
- Author(s)
  Tsuchiya A, Kamimura H, Takamura M,Yamagiwa S, Matsuda Y, Sato Y, Nomoto M,Ichida T, Aoyagi Y
- Journal Title
  
  Hepatol Res
  
  Volume: 39 Pages: 1080-1090
- Data Source
  KAKENHI-PROJECT-21390356
[Journal Article] Clinicopathological analysis of CD133 and NCAM human hepatic stem/progenitor cells in damaged livers and hepatocellular carcinomas2009
- Author(s)
  Tsuchiya A, Kamimura H, Takamura M, Yamagiwa S, Matsuda Y, Sato Y, Nomoto M, Ichida T, Aoyagi Y
- Journal Title
  
  Hepatol Res
  
  Volume: 39(11) Pages: 1080-1090
- NAID
  10027405577
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590835
[Journal Article] Impact of hepatitis B virus X protein on the DNA damage response during hepatocarcinogenesis2009
- Author(s)
  Matsuda Y, Ichida T
- Journal Title
  
  Med Mol Morphol
  
  Volume: 42(3) Pages: 138-142
- NAID
  10025860136
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590835
[Journal Article] Clinicopathological analysis of CD133^+and NCAM^+human hepatic stem/progenitor cells in damaged livers and hepatocellular carcinomas2009
- Author(s)
  Tsuchiya A, Kamimura H, Takamura M, Yamagiwa S, Matsuda Y, Sato Y, Nomoto M, Ichida T, Aoyagi Y
- Journal Title
  
  Hepatol. Res
  
  Volume: 39(11) Pages: 1080-90
- NAID
  10027405577
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590834
[Journal Article] Progression of hypermethylation of the p16(INK4A) gene from normal liver to nontumorous liver and hepatocellular carcinoma : an evaluation using quantitative PCR analysis2009
- Author(s)
  Kurita S, Ohkoshi S, Yano M, Yamazaki K, Suzuki K, Aoki YH, Matsuda Y, Wakai T, Shirai Y, Ichida T, Aoyagi Y
- Journal Title
  
  Dig Dis Sci
  
  Volume: 54(1) Pages: 80-88
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590835
[Journal Article] Molecular mechanism underlying the functional loss of cyclindependent kinase inhibitors p16 and p27 in hepatocellular carcinoma2008
- Author(s)
  Matsuda Y.
- Journal Title
  
  World J Gastroenterol 14(11)
  
  Pages: 1734-1740
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590753
[Journal Article] Temporal treatment with interferon-beta prevents hepatocellular carcinoma in hepatitis B virus X gene transgenic mice2008
- Author(s)
  Yamazaki K, Suzuki K, Ohkoshi S, Yano M, Kurita S, Aoki YH, Toba K, Takamura MA, Yamagiwa S, Matsuda Y, Aoyagi Y
- Journal Title
  
  J Hepatol 48(2)
  
  Pages: 255-265
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590753
[Journal Article] Sca-1+ endothelial cells(SPECs)reside in the portal area of the liver and contribute to rapid recovery from acute liver disease2008
- Author(s)
  Tsuchiya A, Heike T, Baba S, Fujino H, Umeda K, Matsuda Y, Nomoto M, Ichida T, Aoyagi Y, Nakahata T.
- Journal Title
  
  Biochem Biophys Res Commun 365(3)
  
  Pages: 595-601
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590753
[Journal Article] Long-term culture of postnatal mouse hepatic stem/progenitor cells and their relative developmental hierarchy2007
- Author(s)
  Tsuchiya A, Heike T, Baba S, Fujino H, Umeda K, Matsuda Y, Nomoto M, Ichida T, Aoyagi Y, Nakahata T
- Journal Title
  
  Stem Cells 2007 25(4)
  
  Pages: 895-902
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590753
[Journal Article] Tumor suppressor carcinoembryonic antigen-related cell adhesion molecule 1 potentates the anchorage-independent growth of human hepatoma HepG2 cells2007
- Author(s)
  Hokari M, Matsuda Y, Wakai T, Shirai Y, Sato M, Tsuchiya A, Takamura M, Yamagiwa S, Suzuki K, Ohkoshi S, Ichida T, Kawachi H, Aoyagi Y
- Journal Title
  
  Life Sci 81(4)
  
  Pages: 336-345
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590753
[Journal Article] An inhibitor of c-Jun NH2-terminal kinase, SP600125, protects mice from D-galactosamine/lipopolysaccharide-induced hepatic failure by modulating BH3-only proteins2007
- Author(s)
  Takamura M, Matsuda Y, Yamagiwa S, Tamura Y, Honda Y, Suzuki K, Ichida T, Aoyagi Y.
- Journal Title
  
  Life Sci 80(14)
  
  Pages: 1335-1344
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590753
[Journal Article] Altered expression of TLR homolog RP105 on monocytes hypersensitive to LPS in patients with primary biliary cirrhosis2007
- Author(s)
  Honda Y, Yamagiwa S, Matsuda Y, Takamura M,1 Ichida T, Aoyagi Y.
- Journal Title
  
  J Hepatol 47(3)
  
  Pages: 404-411
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590753
[Journal Article] Early upsurge in anti-HBs titer possibly caused by the immunomodulative, not by the mutagenetic effect of interferon and ribavirin2007
- Author(s)
  Yamazaki K, Ohkoshi S, Maruyama M, Aoki YH, Yano M, Kurita S, Suzuki K, Matsuda Y, Sugimura K, Aoyagi Y
- Journal Title
  
  Hepatol Res 37(6)
  
  Pages: 477-81
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590753
[Journal Article] complexities of Raf-dependent and Raf-independent signaling are now unveiled
- Author(s)
  Matsuda Y, Fukumoto M.
- Journal Title
  
  Med Mol Morphol
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590835
[Journal Article] Reduced NKG2D ligand expression in hepatocellular carcinoma correlates with early recurrence
- Author(s)
  Kamimura H, Yamagiwa S, Tsuchiya A, Takamura M, Matsuda Y, Ohkoshi S, Inoue M, Wakai T, Shirai Y, Nomoto M, Aoyagi Y
- Journal Title
  
  J Hepatol
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590835
[Presentation] 家兎気管大欠損モデルにおける代用気管と欠損部再生様式2017
- Author(s)
  窪田　正幸、松田　康伸
- Organizer
  第28回日本小児呼吸器外科研究会
- Data Source
  KAKENHI-PROJECT-16K11343
[Presentation] DJ-1 labeling index is a novel diagnostic biomarker for predicting progression of nonalcoholic steatohepatitis2015
- Author(s)
  Takamura M, Yamagiwa S, Matsuda Y, Nomoto M, Terai S
- Organizer
  アメリカ肝臓病学会（AASLD）第66回年次総会
- Place of Presentation
  Moscone West Convention Center（San Francisco, CA, USA）
- Year and Date
  2015-11-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08991
[Presentation] VALPROIC ACID CONFERS RESISTANCE TO SORAFENIB IN MICE WITH HEPATOCELLULAR CARCINOMA2013
- Author(s)
  Y. Matsuda, M. Osawa, S. Fujimaki, T. Wakai, M. Kubota, M. Takamura, S. Yamagiwa, Y. Aoyagi
- Organizer
  欧州消化器病学会
- Place of Presentation
  ベルリン(ドイツ）
- Data Source
  KAKENHI-PROJECT-24590962
[Presentation] 46th Anuual Meeting of Pacific Association of Pediatric Surgeons2013
- Author(s)
  Kubota M, Matsuda Y, Fujimaki S, Osawa M, Wakai T, Nakaya K
- Organizer
  Effects of rapamycin on the granulation formation in response to using a centrally-doubled coiled stent as a tracheal substitute.
- Place of Presentation
  Hunter Valley, Australia
- Data Source
  KAKENHI-PROJECT-24659773
[Presentation] C型慢性肝炎とインスリン抵抗性因子RBP4RBP4 はインターフェロン治療抵抗性をもたらす2012
- Author(s)
  高橋弘道, 大越章吾, 矢野雅彦, 山際訓, 松田康伸, 池田正徳, 加藤宣之, 青柳豊
- Organizer
  日本肝臓学会総会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-22590722
[Presentation] p21細胞内局在制御によるIFN-βのシスプラチン制癌効果増強機構2012
- Author(s)
  矢野雅彦, 大越章吾, 高橋弘道, 藤巻隼, 松田康伸, 青柳豊, 工藤進英
- Organizer
  日本肝臓学会総会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-22590722
[Presentation] B型肝炎ウイルスX遺伝子によるDNA酸化傷害機構の解析および制御方法の検討2011
- Author(s)
  松田康伸、大越章吾、青柳豊
- Organizer
  第47回日本肝臓学会総会
- Place of Presentation
  東京都港区(ホテルグランパシフィック)
- Year and Date
  2011-06-02
- Data Source
  KAKENHI-PROJECT-21590835
[Presentation] DNA傷害修復因子ATMによる肝癌細胞の細胞死抑制機構の解析2011
- Author(s)
  藤巻隼, 松田康伸, 矢野雅彦, 大越章吾, 若井俊文, 白井良夫, 三瓶歩, 平野茂樹
- Organizer
  日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-22590722
[Presentation] HBx誘導性肝発癌に対するIFN-βの制御機構の分子学的解析2010
- Author(s)
  矢野雅彦, 大越章吾, 青木洋平, 山崎和秀, 栗田聡, 鈴木健太, 三瓶歩, 松田康伸, 青柳豊
- Organizer
  日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-22590722
[Presentation] Hepatitis B Virus X Protein Activates Mammalian Target of Rapamycin mTOR via Reactive Species Generation.2010
- Author(s)
  三瓶歩, 松田康伸, 他7名
- Organizer
  米国肝臓学会
- Place of Presentation
  ボストン(米国)
- Year and Date
  2010-11-02
- Data Source
  KAKENHI-PROJECT-21590835
[Presentation] 骨髄幹細胞による高効率な再生治療をめざしたマウス肝硬変へのG-CSF/CD26阻害ペプチド併用投与2007
- Author(s)
  松田康伸
- Organizer
  第2回新潟細胞再生医療シンポジウム
- Place of Presentation
  新潟大学ベンチャービジネスラボラトリー
- Year and Date
  2007-04-19
- Data Source
  KAKENHI-PROJECT-19590753
[Presentation] TGF-BETA IS A CRITICAL MEDIATOR OF SORAFENIB RESISTANCE IN HEPATOCELLULAR CARCINOMA
- Author(s)
  Y. Matsuda, M. Osawa, T. Wakai, M. Kubota
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24590962

1. YAMAGIWA Satoshi (10419327)

# of Collaborated Projects: 12 results

# of Collaborated Products: 26 results
2. Kobayashi Takashi (40464010)

# of Collaborated Projects: 9 results

# of Collaborated Products: 3 results
3. TAKAMURA Masaaki (20422602)

# of Collaborated Projects: 8 results

# of Collaborated Products: 14 results
4. WAKAI Toshifumi (50372470)

# of Collaborated Projects: 7 results

# of Collaborated Products: 11 results
5. NAGAHASHI Masayuki (30743918)

# of Collaborated Projects: 6 results

# of Collaborated Products: 2 results
6. OHKOSHI Shogo (70231199)

# of Collaborated Projects: 4 results

# of Collaborated Products: 15 results
7. KUBOTA Masayuki (50205150)

# of Collaborated Projects: 4 results

# of Collaborated Products: 9 results
8. 坂田純 (70447605)

# of Collaborated Projects: 4 results

# of Collaborated Products: 1 results
9. SATO Yoshinobu (20313538)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
10. AJIOKA Yoichi (80222610)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
11. YANO Masahiko (70529693)

# of Collaborated Projects: 2 results

# of Collaborated Products: 14 results
12. KOYAMA Yu (10323966)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. KAMEYAMA Hitoshi (40626420)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
14. KOMATSU Masaaki (90356254)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
15. HIRONO Haruka (80386268)

# of Collaborated Projects: 2 results

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16. 廣瀬雄己 (10737365)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
17. 小杉伸一 (90401736)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
18. 三浦宏平 (70733658)

# of Collaborated Projects: 2 results

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19. 諸和樹 (10745566)

# of Collaborated Projects: 2 results

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20. ABO Toru (30005079)

# of Collaborated Projects: 1 results

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21. TOMIYAMA Chikako (80359702)

# of Collaborated Projects: 1 results

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22. SUZUKI Kenji (00303123)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. ICHIDA Takafumi (00126509)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. WATANABE Hisami (50143756)

# of Collaborated Projects: 1 results

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25. Arai Yuhki (50643243)

# of Collaborated Projects: 1 results

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26. Nakano Mae (20790281)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 西條康夫 (10270828)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 五十嵐道弘 (50193173)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 寺井崇二 (00332809)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 長谷川勝彦 (60328870)

# of Collaborated Projects: 1 results

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31. 河野正己 (20170201)

# of Collaborated Projects: 1 results

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32. 石川博 (30089784)

# of Collaborated Projects: 1 results

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33. 木下義晶 (80345529)

# of Collaborated Projects: 1 results

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34. 油座築 (00745565)

# of Collaborated Projects: 1 results

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35. 奥田修二郎 (00512310)

# of Collaborated Projects: 1 results

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36. 島田能史 (20706460)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
37. 市川寛 (50721875)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
38. 宗岡悠介 (00769391)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
39. Sarah Spiegel

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
40. Hylemon Phillip B.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
41. Takabe Kazuaki

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
42. WATANABE kazuhiko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
43. 仲谷健吾

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

MATSUDA Yasunobu 松田 康伸

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肝がんp90RSK含有エクソソームに着目したマルチキナーゼ阻害剤耐性の克服Principal Investigator

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胆管がん腫瘍再増殖の予防法確立を目指したエクソソーム蛋白活性化機構の解析Principal Investigator

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Molecular analysis of the drug resistance mediated by exosomes in biliary tract cancerPrincipal Investigator

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The mechanism of exosome-mediated drug resistance in hepatoma cellsPrincipal Investigator

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MATSUDA Yasunobu 松田康伸