Adachi Hiroaki 足立弘明

… Alternative Names

ADACHI Hiroaki 足立弘明

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Researcher Number	40432257
Other IDs	https://orcid.org/0000-0002-9302-4663
Affiliation (Current)	2024: 産業医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2023: 産業医科大学, 医学部, 教授 2014 – 2021: 産業医科大学, 医学部, 教授 2014: 名古屋大学, 医学系研究科, COE特任講師 2013: 名古屋大学, 医学(系)研究科(研究院), 寄附講座准教授 2013: 名古屋大学, 医学系研究科, 寄附講座准教授 … More 2013: 名古屋大学, 大学院医学系研究科, 寄附講座准教授 2011 – 2012: 名古屋大学, 医学(系)研究科(研究院), COE特任准教授 2011: 名古屋大学, 医学系研究科, 特任講師 2010 – 2011: Nagoya University, 医学系研究科, COE特任講師 2010: 名古屋大学, 大学院・医学系研究科, CEO特任講師 2007 – 2010: Nagoya University, Graduate School of Medicine, Associate Professor 2007: Nagoya University, 大学院・医学研究科, CEO特任講師 2006: 名古屋大学, 大学院医学系研究科, 研究員 Less
Review Section/Research Field	Principal Investigator Neurology / Basic Section 52020:Neurology-related / Biological Sciences Except Principal Investigator Neurology / Biological Sciences
Keywords	Principal Investigator 球脊髄性筋萎縮症 / アンドロゲン受容体 / ポリグルタミン病 / トランスジェニックマウス / CAGリピート / オートファジー / 神経変性疾患 / 分子シャペロン / 凝集体形成抑制 / 神経変性 … More / HIKESHI / 神経栄養因子 / 病因蛋白質の選択的な分解 / 運動ニューロン疾患 / 毒性軽減 / 歯状核赤核淡蒼球ルイ体萎縮症 / Atrophin-1 / ケンペロール / 病態抑止治療 / フラボノール / リソソーム / オートファゴソーム / 認知症 / TRAPPC9 / dynactin1 / muscle weakness / muscle atrophy / neurotrophic factor / CAG repeat / androgen receptor / transgenic mouse / hepatocyte erowth factor / spinal and bulbar muscular atrophy / ダブルトランスジェニックマウス / ドランスジェニックマウス / 筋力低下 / 筋萎縮 / 肝細胞増殖因子 / ユビキチンｰプロテアソーム系 / 筋萎縮性側索硬化症 / TFEB / ユビキチン・プロテアソーム系 / AAVベクター / Dicer / miR-196a / 運動ニューロン病 / CELF2 / miRNA / アンドロゲンレセプター / GDNF / BDNF / 2アミノ酸剤 / ユビキチンープロテアソーム系 / Hsp90阻害剤 / 17-DMAG / ユビキチン-プロテアソーム系 / ペオニ抽出物 … More Except Principal Investigator 運動ニューロン / 球脊髄性筋萎縮症 / 神経変性 / ポリグルタミン / 神経変性疾患 / 細胞周期 / マイクロアレイ / 運動ニューロン疾患 / サイクリン依存性キナーゼ / 骨格筋 / TGF-β / 転写障害 / JNK / ポリグルタミン病 / 熱ショック蛋白質 / アンドロゲン受容体 / 分子シャペロン / 発現制御 / 核酸 / 遺伝子 / トランスレーショナルリサーチ / 脳神経疾患 / 神経筋接合部 / シナプス / セロトニン受容体 / 神経ペプチド / naratriptan / CGRP1 / CGRP-1 / 筋萎縮性側索硬化 / サーキット変性 / レンチウイルスベクター / heat shock factor-1 / TGF-beta / ミトコンドリア / 酸化ストレス / 筋萎縮性側索硬化症 / calcitonin-related polypeptide(CGRP1) / calcitonin / calcitonin/calcitonin-related polypeptide(CGRP1) / セロトニン受容体アゴニスト / ユビチキン / プロテアソーム / ユビキチン / )球脊髄性筋萎縮症 / オートファジー / ユビキチン-プロテアゾーム系 / 遺伝子発現解析 / dynactinl / 疾患モデル / 線虫 / cyclin C / dynactin1 / ALS / ユビキチン・プロテアソーム / CAGリピート / リュープロレリン / ユビキチンープロテアソーム / 神経分子病態学 Less

Reducing toxicity of disease-causative molecules with the aim of developing therapies for neurodegenerative diseasesPrincipal Investigator
- Principal Investigator
  
  足立弘明
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  University of Occupational and Environmental Health, Japan
Reducing toxicity of disease-causative molecules with the aim of developing therapies for neurodegenarative diseasesPrincipal Investigator
- Principal Investigator
  
  Adachi Hiroaki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  University of Occupational and Environmental Health, Japan
Discovery of novel autophagy regulators for treatment of neurodegenerative diseasesPrincipal Investigator
- Principal Investigator
  
  足立弘明
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  University of Occupational and Environmental Health, Japan
Selective protein degradation with the aim of developing therapies for neurodegenarative diseasesPrincipal Investigator
- Principal Investigator
  
  Adachi Hiroaki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurology
- Research Institution
  University of Occupational and Environmental Health, Japan
Therapeutic strategy of neurodegenerative disease using microRNA
- Principal Investigator
  
  SOBUE Gen
- Project Period (FY)
  2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Neurology
- Research Institution
  Nagoya University
Elucidation of activity-dependent synapse pathology and development of therapy for spinal and bulbar muscular atrophy
- Principal Investigator
  
  KATSUNO MASAHISA
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Neurology
- Research Institution
  Nagoya University
Development of therapy targeting dysregulation of cell cycle and JNK pathway in polyglutamine diseases
- Principal Investigator
  
  KATSUNO MASAHISA
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurology
- Research Institution
  Nagoya University
Novel therapeutic approaches using the delivery of specific miRNAs for polyglutamine diseasesPrincipal Investigator
- Principal Investigator
  
  ADACHI Hiroaki
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurology
- Research Institution
  Nagoya University
Elucidation of molecular pathogenesis in motor neurocircuit degeneration and development of therapy for motor neuron diseases
- Principal Investigator
  
  KATSUNO Masahisa
- Project Period (FY)
  2010 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Nagoya University
Development of Molecular Targeted Disease Modifying Therapy for Polyglutamine Diseases
- Principal Investigator
  
  SOBUE Gen
- Project Period (FY)
  2009 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Neurology
- Research Institution
  Nagoya University
ポリグルタミン病の病態抑止治療と神経賦活治療の併用療法Principal Investigator
- Principal Investigator
  
  足立弘明
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Neurology
- Research Institution
  Nagoya University
Therapeutic strategy for polyglutamine-mediated motor neuron disease via molecular chaperone-ubiquitin proteasome systemPrincipal Investigator
- Principal Investigator
  
  ADACHI Hiroaki
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurology
- Research Institution
  Nagoya University
Pathogenesis-based therapy development for polyglutamine diseases
- Principal Investigator
  
  SOBUE Gen
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Neurology
- Research Institution
  Nagoya University
Development of animal model for sporadic ALS
- Principal Investigator
  
  TANAKA Fumiaki
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurology
- Research Institution
  Nagoya University
Development of therapies in polyglutamine diseases using hepatocyte growth factor (HGF)Principal Investigator
- Principal Investigator
  
  ADACHI Hiroaki
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Nagoya University

[Book] 今日の治療指針ミオクローヌス2021
- Author(s)
  足立弘明
- Total Pages
  2192
- Publisher
  医学書院
- ISBN
  9784260042833
- Data Source
  KAKENHI-PROJECT-19K07970
[Book] 今日の治療指針2020
- Author(s)
  足立弘明
- Total Pages
  2192
- Publisher
  医学書院
- ISBN
  4260039407
- Data Source
  KAKENHI-PROJECT-19K07970
[Book] 今日の診断指針2020
- Author(s)
  足立弘明
- Total Pages
  2079
- Publisher
  医学書院
- ISBN
  4260038087
- Data Source
  KAKENHI-PROJECT-19K07970
[Book] 産業医が診る働き方改革増補改訂版2020
- Author(s)
  足立弘明
- Total Pages
  232
- Publisher
  西日本新聞社
- ISBN
  4816709762
- Data Source
  KAKENHI-PROJECT-19K07970
[Book] 球脊髄性筋萎縮症に対する分子標的治療法の開発.すべてがわかるALS・運動ニューロン疾患辻省次, 祖父江元編2013
- Author(s)
  勝野雅央, 足立弘明, 祖父江元
- Publisher
  中山書店
- Data Source
  KAKENHI-PROJECT-23390231
[Book] すべてがわかるALS・運動ニューロン疾患2013
- Author(s)
  勝野雅央、足立弘明、祖父江元
- Total Pages
  384
- Publisher
  中山書店
- Data Source
  KAKENHI-PROJECT-23390231
[Journal Article] Olfactory-cognitive index distinguishes involvement of frontal lobe shrinkage, as in sarcopenia from shrinkage of medial temporal areas, and global brain, as in Kihon Checklist frailty/dependence, in older adults with progression of normal cognition to Alzheimer's disease.2021
- Author(s)
  Iritani O, Okuno T, Miwa T, Makizako H, Okutani F, Kashibayashi T, Suzuki K, Hara H, Mori E, Omoto S, Suzuki H, Shibata M, Adachi H, Kondo K, Umeda-Kameyama Y, Kodera K, Morimoto S.
- Journal Title
  
  Geriatr Gerontol Int
  
  Volume: 21 Issue: 3 Pages: 291-298
- DOI
  10.1111/ggi.14128
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11219, KAKENHI-PROJECT-20K07849, KAKENHI-PROJECT-19K07970, KAKENHI-PROJECT-20K07890, KAKENHI-PROJECT-21H03090
[Journal Article] Electrophysiological findings in neuromyelitis optica spectrum disorder.2021
- Author(s)
  Ohnari K, Adachi H.
- Journal Title
  
  On J Neur & Br Disord
  
  Volume: 5 Issue: 1 Pages: 420-425
- DOI
  10.32474/ojnbd.2021.05.000203
- NAID
  40022273355
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07970
[Journal Article] Complete sequencing of expanded SAMD12 repeats by long-read sequencing with Cas9-mediated enrichment.2021
- Author(s)
  Mizuguchi T, Toyota T, Miyatake S, Mitsuhashi S, Doi H, Kudo Y, Kishida H, Hayashi N, Tusburaya RS, Kinoshita M, Fukuyama T, Fukuda H, Koshimizu E, Tsuchida N, Uchiyama Y, Fujita A, Takata A, Miyake N, Kato M, Tanaka F, Adachi H, Matsumoto N.
- Journal Title
  
  Brain
  
  Volume: 144 Issue: 4 Pages: 1103-1117
- DOI
  10.1093/brain/awab021
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07970, KAKENHI-PLANNED-20H05777, KAKENHI-PROJECT-19H03621, KAKENHI-PROJECT-21H02855, KAKENHI-PROJECT-20K07907, KAKENHI-PROJECT-20K08164, KAKENHI-PROJECT-20K08236, KAKENHI-PROJECT-21K07298, KAKENHI-PROJECT-21K15704
[Journal Article] Unclassified subtype of Guillain-Barre syndrome is associated with quick recovery.2021
- Author(s)
  Ohnari K, Okada K, Mafune K, Kusunoki S, Adachi H.
- Journal Title
  
  J Clin Neurosci
  
  Volume: 91 Pages: 313-318
- DOI
  10.1016/j.jocn.2021.07.025
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07970
[Journal Article] Eating Disorder Neuroimaging Initiative (EDNI): a multicentre prospective cohort study protocol for elucidating the neural effects of cognitive?behavioural therapy for eating disorders2021
- Author(s)
  Hamatani S, Hirano Y, Sugawara A, Isobe M, Kodama N, Yoshihara K, Moriguchi Y, Ando T, Endo Y, Takahashi J, Nohara N, Takamura T, Hori H, Noda T, Tose K, Watanabe K, Adachi H, Gondo M, Takakura S, Fukudo S, Shimizu E, Yoshiuchi K, Sato Y, Sekiguchi A.
- Journal Title
  
  BMJ Open
  
  Volume: 11 Issue: 1 Pages: e042685-e042685
- DOI
  10.1136/bmjopen-2020-042685
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K17313, KAKENHI-PROJECT-19J00227, KAKENHI-PROJECT-19K07970
[Journal Article] Arginine is a disease modifier for polyQ disease models that stabilizes polyQ protein conformation.2020
- Author(s)
  Minakawa EN, Popiel HA, Tada M, Takahashi T, Yamane H, Saitoh Y, Takahashi Y, Ozawa D, Takeda A, Takeuchi T, Okamoto Y, Yamamoto K, Suzuki M, Fujita H, Ito C, Yagihara H, Saito Y, Watase K, Adachi H, Katsuno M, Mochizuki H, Shiraki K, Sobue G, Toda T, Wada K, Onodera O, Nagai Y.
- Journal Title
  
  Brain
  
  Volume: 143 Issue: 6 Pages: 1811-1825
- DOI
  10.1093/brain/awaa115
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07970, KAKENHI-PROJECT-19K07987, KAKENHI-PROJECT-20K07737, KAKENHI-PROJECT-17K09755, KAKENHI-PLANNED-20H05927
[Journal Article] Hippocampal sclerosis without visually detectable hippocampal MRI abnormalities: automated subfield volumetric analysis2020
- Author(s)
  Masaki Hiromi、Watanabe Keita、Kakeda Shingo、Ide Satoru、Sugimoto Kohichiro、Ueda Issei、Hamamura Toshihiko、Hisanaga Sachi、Toyota Tomoko、Akamatsu Naoki、Shimajiri Shohei、Yamamoto Junkoh、Nishizawa Shigeru、Adachi Hiroaki、Korogi Yukunori
- Journal Title
  
  Japanese Journal of Radiology
  
  Volume: 38 Issue: 11 Pages: 1020-1027
- DOI
  10.1007/s11604-020-01019-y
- NAID
  50014626761
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07970
[Journal Article] Muscle BDNF improves synaptic and contractile muscle strength in Kennedy's disease mice in a muscle‐type specific manner2020
- Author(s)
  Halievski Katherine、Xu Youfen、Haddad Yazeed W.、Tang Yu Ping、Yamada Shinichiro、Katsuno Masahisa、Adachi Hiroaki、Sobue Gen、Breedlove S. Marc、Jordan Cynthia L.
- Journal Title
  
  The Journal of Physiology
  
  Volume: in press Issue: 13 Pages: 2719-2739
- DOI
  10.1113/jp279208
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07970
[Journal Article] The facial nerve atrophy with spinal and bulbar muscular atrophy patients (SBMA): Three case reports with 3D fast imaging employing steady-state acquisition (FIESTA)2019
- Author(s)
  Miyata Mari、Kakeda Shingo、Hashimoto Tomoyo、Korogi Yukunori、Adachi Hiroaki
- Journal Title
  
  Journal of the Neurological Sciences
  
  Volume: 406 Pages: 116461-116461
- DOI
  10.1016/j.jns.2019.116461
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07970
[Journal Article] DNA methylation inhibitor attenuates polyglutamine-induced neurodegeneration by regulating Hes52019
- Author(s)
  Kondo N, Tohnai G, Sahashi K, Iida M, Kataoka M, Nakatsuji H, Tsutsumi Y, Hashizume A, Adachi H, Koike H, Shinjo K, Kondo Y, Sobue G, Katsuno M.
- Journal Title
  
  EMBO Mol Med
  
  Volume: none Issue: 5
- DOI
  10.15252/emmm.201708547
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-17H05708, KAKENHI-PROJECT-17H04195, KAKENHI-PROJECT-19K07970, KAKENHI-PROJECT-17H03582, KAKENHI-PROJECT-17J40128, KAKENHI-PROJECT-18K15361
[Journal Article] Detection of dentate nuclei abnormality in a patient with dentatorubral-pallidoluysian atrophy using the quantitative susceptibility mapping2019
- Author(s)
  Ide Satoru、Kakeda Shingo、Adachi Hiroaki、Miyata Mari、Iwanaka Yukio、Okada Kazumasa、Korogi Yukunori
- Journal Title
  
  Journal of the Neurological Sciences
  
  Volume: 403 Pages: 97-98
- DOI
  10.1016/j.jns.2019.06.020
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07970
[Journal Article] Facial nerve atrophy in patients with amyotrophic lateral sclerosis: Evaluation with fast imaging employing steady‐state acquisition (FIESTA)2019
- Author(s)
  Miyata Mari、Kakeda Shingo、Hashimoto Tomoyo、Ide Satoru、Okada Kazumasa、Adachi Hiroaki、Korogi Yukunori
- Journal Title
  
  Journal of Magnetic Resonance Imaging
  
  Volume: 51 Issue: 3 Pages: 757-766
- DOI
  10.1002/jmri.26890
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07970
[Journal Article] Tandem-genotypes: robust detection of tandem repeat expansions from long DNA reads2019
- Author(s)
  Satomi Mitsuhashi, Martin C. Frith, Takeshi Mizuguchi, Satoko Miyatake, Tomoko Toyota, Hiroaki Adachi, Yoko Oma, Yoshihiro Kino, Hiroaki Mitsuhashi, Naomichi Matsumoto
- Journal Title
  
  Genome Biology
  
  Volume: 20 Issue: 1 Pages: 58-58
- DOI
  10.1186/s13059-019-1667-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09683, KAKENHI-PROJECT-17K10080, KAKENHI-PUBLICLY-17H05708, KAKENHI-PROJECT-17H01539, KAKENHI-PROJECT-17K15630, KAKENHI-PROJECT-19K07970
[Journal Article] Disease Affects Bdnf Expression in Synaptic and Extrasynaptic Regions of Skeletal Muscle of Three SBMA Mouse Models2019
- Author(s)
  Halievski K, Nath SR, Katsuno M, Adachi H, Sobue G, Breedlove SM, Lieberman AP, Jordan CL.
- Journal Title
  
  Int J Mol Sci
  
  Volume: 20 Issue: 6 Pages: 1314-1314
- DOI
  10.3390/ijms20061314
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05708, KAKENHI-PROJECT-17H04195, KAKENHI-PROJECT-19K07970
[Journal Article] Src inhibition attenuates polyglutamine-mediated neuromuscular degeneration in spinal and bulbar muscular atrophy2019
- Author(s)
  Iida Madoka、Sahashi Kentaro、Kondo Naohide、Nakatsuji Hideaki、Tohnai Genki、Tsutsumi Yutaka、Noda Seiya、Murakami Ayuka、Onodera Kazunari、Okada Yohei、Nakatochi Masahiro、Tsukagoshi Okabe Yuka、Shimizu Shinobu、Mizuno Masaaki、Adachi Hiroaki、Okano Hideyuki、Sobue Gen、Katsuno Masahisa
- Journal Title
  
  Nature Communications
  
  Volume: 10 Issue: 1 Pages: 4262-4262
- DOI
  10.1038/s41467-019-12282-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07970, KAKENHI-PROJECT-18K16656, KAKENHI-PROJECT-17H04195, KAKENHI-PROJECT-17J40128, KAKENHI-PROJECT-18K15361
[Journal Article] Potential usefulness of signal intensity of cerebral gyri on quantitative susceptibility mapping for discriminating corticobasal degeneration from progressive supranuclear palsy and Parkinson's disease.2019
- Author(s)
  Miyata M, Kakeda S, Toyoshima Y, Ide S, Okada K, Adachi H, Wang Y, Korogi Y.
- Journal Title
  
  Neuroradiology
  
  Volume: 61 Issue: 11 Pages: 1251-1259
- DOI
  10.1007/s00234-019-02253-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07970
[Journal Article] Increased expression level of Hsp70 in the inner ears of mice by exposure to low frequency noise.2018
- Author(s)
  Ninomiya H, Ohgami N, Oshino R, Kato M, Ohgami K, Li X, Shen D, Iida M, Yajima I, Angelidis CE, Adachi H, Katsuno M, Sobue G, Kato M.
- Journal Title
  
  Hear Res
  
  Volume: - Pages: 49-54
- DOI
  10.1016/j.heares.2018.02.006
- NAID
  120006517664
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08343, KAKENHI-PROJECT-16K08440, KAKENHI-PUBLICLY-16H01639, KAKENHI-PUBLICLY-17H05708, KAKENHI-PROJECT-16K10152, KAKENHI-PROJECT-15H01743, KAKENHI-PUBLICLY-18H04975, KAKENHI-PROJECT-15H02588, KAKENHI-PROJECT-16K11177, KAKENHI-ORGANIZER-15H05935
[Journal Article] Systemic overexpression of SQSTM1/p62 accelerates disease onset in a SOD1H46R-expressing ALS mouse model2018
- Author(s)
  Mitsui S, Otomo A, Nozaki M, Ono S, Sato K, Shirakawa R, Adachi H, Aoki M, Sobue G, Shang HF, Hadano S
- Journal Title
  
  Mol Brain
  
  Volume: 11 Issue: 1 Pages: 30-30
- DOI
  10.1186/s13041-018-0373-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-17H05708
[Journal Article] Pre-clinical symptoms of SBMA may not be androgen-dependent: Implications from two SBMA mouse models.2018
- Author(s)
  Xu Y, Halievski K, Katsuno M, Adachi H, Sobue G, Breedlove M, Jordan CL.
- Journal Title
  
  Hum Mol Genet in press
  
  Volume: 未 Issue: 14 Pages: 2425-2442
- DOI
  10.1093/hmg/ddy142
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05708, KAKENHI-PROJECT-17H04195
[Journal Article] Detecting a long insertion variant in SAMD12 by SMRT sequencing: implications of long-read whole-genome sequencing for repeat expansion diseases2018
- Author(s)
  Mizuguchi Takeshi、Toyota Tomoko、Adachi Hiroaki、Miyake Noriko、Matsumoto Naomichi、Miyatake Satoko
- Journal Title
  
  Journal of Human Genetics
  
  Volume: 64 Issue: 3 Pages: 191-197
- DOI
  10.1038/s10038-018-0551-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10080, KAKENHI-PUBLICLY-17H05708, KAKENHI-PROJECT-17H01539, KAKENHI-PROJECT-17K15630, KAKENHI-PROJECT-19K07970
[Journal Article] Myoclonia continua in primary central nervous system natural killer/T-cell lymphoma, nasal type.2017
- Author(s)
  Toyota T, Sennari Y, Okada K, Kawahara A, Tsukada J, Shimajiri S, Adachi H.
- Journal Title
  
  Neurology
  
  Volume: 88 Issue: 3 Pages: 329-330
- DOI
  10.1212/wnl.0000000000003515
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-17H05708
[Journal Article] Coexisting infectious diseases on admission as a risk factor for mechanical ventilation in patients with Guillain–Barré syndrome2017
- Author(s)
  Kobori S, Kubo T, Otani M, Muramatsu K, Fujino Y, Adachi H, Horiguchi H, Fushimi K, Matsuda S.
- Journal Title
  
  Journal of Epidemiology
  
  Volume: 27 Issue: 7 Pages: 311-316
- DOI
  10.1016/j.je.2016.07.003
- NAID
  130005709468
- ISSN
  0917-5040, 1349-9092
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-17H05708
[Journal Article] Defects in neuromuscular transmission may underlie motor dysfunction in SBMA.2016
- Author(s)
  Xu Y, Halievski K, Henley C, Atchison W, Katsuno M, Adachi H, Sobue G, Breedlove S, Jordan CL.
- Journal Title
  
  J Neurosci
  
  Volume: 36 Issue: 18 Pages: 5094-5106
- DOI
  10.1523/jneurosci.3485-15.2016
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293207
[Journal Article] FUS/TLS acts as an aggregation-dependent modifier of polyglutamine disease model mice.2016
- Author(s)
  Kino Y, Washizu C, Kurosawa M, Yamada M, Doi H, Takumi T, Adachi H, Katsuno M, Sobue G, Hicks GG, Hattori N, Shimogori T, Nukina N.
- Journal Title
  
  Sci Rep.
  
  Volume: 6 Issue: 1 Pages: 35236-35236
- DOI
  10.1038/srep35236
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01567, KAKENHI-PLANNED-16H06463, KAKENHI-PROJECT-16H06316, KAKENHI-PROJECT-26293206, KAKENHI-PROJECT-26293207, KAKENHI-PROJECT-25461299, KAKENHI-PROJECT-16K09683
[Journal Article] Natural Compounds Preventing Neurodegenerative Diseases Through Autophagic Activation2016
- Author(s)
  Huang Z, Adachi H.
- Journal Title
  
  Journal of UOEH
  
  Volume: 38 Issue: 2 Pages: 139-148
- DOI
  10.7888/juoeh.38.139
- NAID
  130005157739
- ISSN
  0387-821X, 2187-2864
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293207
[Journal Article] Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)2016
- Author(s)
  Klionsky DJ., Abdelmohsen K., Abe A., Abedin MJ.,Inomata M., et al.
- Journal Title
  
  Autophagy
  
  Volume: 12(1) Issue: 1 Pages: 1-222
- DOI
  10.1080/15548627.2015.1100356
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K11094, KAKENHI-PROJECT-15K14681, KAKENHI-PROJECT-15K14951, KAKENHI-PUBLICLY-15H01239, KAKENHI-PUBLICLY-15H01380, KAKENHI-ORGANIZER-24118001, KAKENHI-PLANNED-24118007, KAKENHI-PLANNED-26110003, KAKENHI-PUBLICLY-26111501, KAKENHI-PUBLICLY-26111503, KAKENHI-PUBLICLY-26111505, KAKENHI-PUBLICLY-26111514, KAKENHI-PUBLICLY-26111521, KAKENHI-PUBLICLY-26117727, KAKENHI-PROJECT-15H05298, KAKENHI-PROJECT-15H06095, KAKENHI-PROJECT-25460072, KAKENHI-PROJECT-25461364, KAKENHI-PROJECT-25462920, KAKENHI-PROJECT-26670446, KAKENHI-PROJECT-26670906, KAKENHI-PROJECT-25850198, KAKENHI-PROJECT-25290014, KAKENHI-PROJECT-25291040, KAKENHI-PROJECT-25291042, KAKENHI-PROJECT-25293383, KAKENHI-PROJECT-26290018, KAKENHI-PROJECT-26291039, KAKENHI-PROJECT-26292032, KAKENHI-PROJECT-26293179, KAKENHI-PROJECT-26713005, KAKENHI-PUBLICLY-15H01545, KAKENHI-PUBLICLY-15H01572, KAKENHI-ORGANIZER-25111001, KAKENHI-PLANNED-25111003, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-26253094, KAKENHI-PROJECT-16H05291, KAKENHI-PROJECT-16J00431, KAKENHI-PROJECT-26293070, KAKENHI-PROJECT-26293207, KAKENHI-PROJECT-25711005, KAKENHI-PROJECT-26430050, KAKENHI-PROJECT-15K06791, KAKENHI-PROJECT-15K08376, KAKENHI-PROJECT-15K10908, KAKENHI-PROJECT-15K11079, KAKENHI-PROJECT-15K12749, KAKENHI-PROJECT-16K15194, KAKENHI-PROJECT-16K15790, KAKENHI-PROJECT-16K15853, KAKENHI-PROJECT-15K16486, KAKENHI-PROJECT-16H05107, KAKENHI-PROJECT-20H03453
[Journal Article] BIIB021, a synthetic Hsp90 inhibitor, induces mutant ataxin-1 degeneration through the activation of heat shock factor 1.2016
- Author(s)
  Ding Y, Adachi H, Katsuno M, Sahashi K, Kondo N, Iida M, Tohnai G, Nakatsuji H, Sobue G
- Journal Title
  
  Neuroscience
  
  Volume: S0306-4522 Pages: 30051-30053
- DOI
  10.1016/j.neuroscience.2016.03.064
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26860665, KAKENHI-PROJECT-26293207, KAKENHI-PROJECT-15K19482
[Journal Article] Impaired muscle uptake of creatine in spinal and bulbar muscular atrophy.2016
- Author(s)
  Hijikata Y., Katsuno M., Suzuki K., Hashizume A., Araki A., Yamada S., Inagaki T., Iida M., Noda S., Nakanishi H., Banno H., Mano T., Hirakawa A., Adachi H., Watanabe H., Yamamoto M., Sobue G.
- Journal Title
  
  Ann Clin Transl Neurol
  
  Volume: 3 Issue: 7 Pages: 537-546
- DOI
  10.1002/acn3.324
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-26117002, KAKENHI-PROJECT-26293206, KAKENHI-PROJECT-26293207, KAKENHI-PROJECT-15K15338, KAKENHI-ORGANIZER-26117001
[Journal Article] Pioglitazone suppresses neuronal and muscular degeneration caused by polyglutamine-expanded androgen receptors.2015
- Author(s)
  Iida M, Katsuno M, Nakatsuji H, Adachi H, Kondo N, Miyazaki Y, Tohnai G, Ikenaka K, Watanabe H, Yamamoto M, Kishida K, Sobue G
- Journal Title
  
  Hum Mol Genet.
  
  Volume: 24 Issue: 2 Pages: 314-329
- DOI
  10.1093/hmg/ddu445
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-22110005, KAKENHI-ORGANIZER-26117001, KAKENHI-PROJECT-26670439, KAKENHI-PROJECT-26670440, KAKENHI-PROJECT-26860665, KAKENHI-PROJECT-26293206, KAKENHI-PLANNED-26117002
[Journal Article] Anti-androgen flutamide protects male mice from androgen-dependent toxicity in three models of spinal bulbar muscular atrophy2014
- Author(s)
  Renier KJ, Troxell-Smith SM, Johansen JA, Katsuno M, Adachi H, Sobue G, Chua JP, Sun Kim H, Lieberman AP, Breedlove SM, Jordan CL
- Journal Title
  
  Endocrinology
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229011
[Journal Article] Paeoniflorin eliminates a mutant AR via NF-YA-dependent proteolysis in spinal and bulbar muscular atrophy2014
- Author(s)
  Tohnai G, Adachi H, Katsuno M, Doi H, Matsumoto S, Kondo N, Miyazaki Y, Iida M, Nakatsuji H, Qiang Q, Ding Y, Watanabe H, Yamamoto M, Ohtsuka K, Sobue G
- Journal Title
  
  Hum Mol Genet
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390230
[Journal Article] Transcriptional activation of TFEB/ZKSCAN3 target genes underlies enhanced autophagy in spinobulbar muscular atrophy2014
- Author(s)
  Chua JP, Reddy SL, Merry DE, Adachi H, Katsuno M, Sobue G, Robins DM, Lieberman AP
- Journal Title
  
  Hum Mol Genet
  
  Volume: (Epub ahead of print) Issue: 5 Pages: 1376-1386
- DOI
  10.1093/hmg/ddt527
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229011, KAKENHI-PLANNED-22110005, KAKENHI-PROJECT-23390230, KAKENHI-PROJECT-24659428
[Journal Article] Anti-androgen flutamide protects male mice from androgen-dependent toxicity in three models of spinal bulbar muscular atrophy2014
- Author(s)
  Renier KJ, Troxell-Smith SM, Johansen JA, Katsuno M, Adachi H, Sobue G, Chua JP, Sun Kim H, Lieberman AP, Breedlove SM, Jordan CL
- Journal Title
  
  Endocrinology.
  
  Volume: 155 Issue: 7 Pages: 2624-2634
- DOI
  10.1210/en.2013-1756
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22110005, KAKENHI-PROJECT-26293206, KAKENHI-PROJECT-26670440
[Journal Article] Anti-androgen flutamide protects male mice from androgen-dependent toxicity in three models of spinal bulbar muscular atrophy2014
- Author(s)
  Renier KJ, Troxell-Smith SM, Johansen JA, Katsuno M, Adachi H, Sobue G, Chua JP, Sun Kim H, Lieberman AP, Breedlove SM, Jordan CL
- Journal Title
  
  Endocrinology
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390230
[Journal Article] Paeoniflorin eliminates a mutant AR via NF-YA-dependent proteolysis in spinal and bulbar muscular atrophy.2014
- Author(s)
  Tohnai G, Adachi H, Katsuno M, Doi H, Matsumoto S, Kondo N, Miyazaki Y, Iida M, Nakatsuji H, Qiang Q, Ding Y, Watanabe H, Yamamoto M, Ohtsuka K, Sobue G.
- Journal Title
  
  Hum Mol Genet.
  
  Volume: 23 Issue: 13 Pages: 3552-3565
- DOI
  10.1093/hmg/ddu066
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22110005, KAKENHI-ORGANIZER-26117001, KAKENHI-PROJECT-26293206, KAKENHI-PROJECT-26670440, KAKENHI-PROJECT-26860665, KAKENHI-PLANNED-26117002
[Journal Article] Paeoniflorin eliminates a mutant AR via NF-YA-dependent proteolysis in spinal and bulbar muscular atrophy2014
- Author(s)
  Tohnai G, Adachi H, Katsuno M, Doi H, Matsumoto S, Kondo N, Miyazaki Y, Iida M, Nakatsuji H, Qiang Q, Ding Y, Watanabe H, Yamamoto M, Ohtsuka K, Sobue G
- Journal Title
  
  Hum Mol Genet
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229011
[Journal Article] Paeoniflorin eliminates a mutant AR via NF-YA-dependent proteolysis in spinal and bulbar muscular atrophy2014
- Author(s)
  Tohnai G, Adachi H, Katsuno M, Doi H, Matsumoto S, Kondo N, Miyazaki Y, Iida M, Nakatsuji H, Qiang Q, Ding Y, Watanabe H, Yamamoto M, Ohtsuka K, Sobue G.
- Journal Title
  
  Hum Mol Genet
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659428
[Journal Article] Heat shock factor-1 influences pathological lesion distribution of polyglutamine-induced neurodegeneration2013
- Author(s)
  Kondo N, Katsuno M, Adachi H, Minamiyama M, Doi H, Matsumoto S, Miyazaki Y, Iida M, Tohnai G, Nakatsuji H, Ishigaki S, Fujioka Y, Watanabe H, Tanaka F, Nakai A, Sobue G
- Journal Title
  
  Nat Commun
  
  Volume: 4 Issue: 1 Pages: 1405-1405
- DOI
  10.1038/ncomms2417
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229011, KAKENHI-PROJECT-23390230, KAKENHI-PROJECT-24659428, KAKENHI-PLANNED-22110005
[Journal Article] Androgen receptor inclusions acquire GRP78/BiP to ameliorate androgen-induced protein misfolding stress in embryonic stem cells.2013
- Author(s)
  Yang YC, Fu HC, Hsiao BL, Sobue G, Adachi H, Huang FJ, Hsuuw YD, Wei KT, Chang C, Huang KE, Kang HY.
- Journal Title
  
  Cell Death Dis.
  
  Volume: 4 Issue: 4 Pages: e607-e607
- DOI
  10.1038/cddis.2013.122
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229011
[Journal Article] p62/SQSTM1 differentially removes the toxic mutant androgen receptor via autophagy and inclusion formation in a spinal and bulbar muscular atrophy mouse model2013
- Author(s)
  Doi H, Adachi H, Katsuno M, Minamiyama M, Matsumoto S, Kondo N, Miyazaki Y, IidaM,Tohnai G, Qiang Q, Tanaka F, Yanagawa T, WarabiE,Ishii T, Sobue G
- Journal Title
  
  J Neurosci
  
  Volume: 33 Issue: 18 Pages: 7710-7727
- DOI
  10.1523/jneurosci.3021-12.2013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229011, KAKENHI-PLANNED-22110005, KAKENHI-PROJECT-23390230, KAKENHI-PROJECT-23390231, KAKENHI-PROJECT-24659428, KAKENHI-PROJECT-25220103
[Journal Article] RNP2 of RNA recognition motif 1 plays a central role in the aberrant modification of TDP-43.2013
- Author(s)
  Takagi S, Iguchi Y, Katsuno M, Ishigaki S, Ikenaka K, Fujioka Y, Honda D, Niwa J, Tanaka F, Watanabe H, Adachi H, Sobue G.
- Journal Title
  
  PLoS One.
  
  Volume: 28 Issue: 6 Pages: e66966-e66966
- DOI
  10.1371/journal.pone.0066966
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22110005, KAKENHI-PROJECT-25293207
[Journal Article] Distinct acoustic features in spinal and bulbar muscular atrophy patients with laryngospasm.2013
- Author(s)
  Tanaka S, Banno H, Katsuno M, Suzuki K, Suga N, Hashizume A, Mano T, Araki A, Watanabe H, Adachi H, Tatsumi H, Yamamoto M, Sobue G.
- Journal Title
  
  J Neurol Sci.
  
  Volume: 337 Issue: 1-2 Pages: 193-200
- DOI
  10.1016/j.jns.2013.12.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229011, KAKENHI-PLANNED-22110005
[Journal Article] Genistein, a natural product derived from soybeans, ameliorates polyglutamine-mediated motor neuron disease2013
- Author(s)
  Qiang Q, Adachi H, Huang Z, Jiang YM, Katsuno M, Minamiyama M, Doi H, Matsumoto S, Kondo N, Miyazaki Y, Iida M, Tohnai G, Sobue G
- Journal Title
  
  J Neurochem
  
  Volume: 126 Issue: 1 Pages: 122-130
- DOI
  10.1111/jnc.12172
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229011, KAKENHI-PROJECT-23390230, KAKENHI-PROJECT-23390231, KAKENHI-PROJECT-24659428
[Journal Article] Viral delivery of miR-196a ameliorates the SBMA phenotype via the silencing of CELF22012
- Author(s)
  Miyazaki Y, Adachi H, Katsuno M, Minamiyama M, Jiang YM, Huang Z, Doi H, Matsumoto S, Kondo N, Iida M, Tohnai G, Tanaka F, Muramatsu S, Sobue G
- Journal Title
  
  Nat Med
  
  Volume: 18 Issue: 7 Pages: 1136-1141
- DOI
  10.1038/nm.2791
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229011, KAKENHI-PROJECT-23390231, KAKENHI-PROJECT-23590473, KAKENHI-PUBLICLY-23110515
[Journal Article] Pathogenesis and therapy of spinal and bulbar muscular atrophy (SBMA)2012
- Author(s)
  Katsuno M, Tanaka F, Adachi H, Banno H, Suzuki K, Watanabe H, Sobue G
- Journal Title
  
  Prog Neurobiol
  
  Volume: 99 Issue: 3 Pages: 246-256
- DOI
  10.1016/j.pneurobio.2012.05.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229011, KAKENHI-PROJECT-23390230, KAKENHI-PROJECT-23790986, KAKENHI-PROJECT-24659428
[Journal Article] Naratriptan mitigates CGRP1-associated motor neuron degeneration caused by expanded polyglutamine2012
- Author(s)
  Minamiyama M, Katsuno M, Adachi H, Doi H, Kondo N, Iida M, Ishigaki S, Fujioka Y, Matsumoto S, Miyazaki Y, Tanaka F, Kurihara H, Sobue G
- Journal Title
  
  Nat Med
  
  Volume: 18 Issue: 10 Pages: 1531-1538
- DOI
  10.1038/nm.2932
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229011, KAKENHI-PUBLICLY-23013007, KAKENHI-PROJECT-23390230, KAKENHI-PROJECT-23659107, KAKENHI-PROJECT-24249047
[Journal Article] c-Abl inhibition delays motor neuron degeneration in the G93A mouse, an animal model of amyotrophic lateral sclerosis2012
- Author(s)
  Katsumata R
- Journal Title
  
  PLoS One
  
  Volume: 7 Issue: 9 Pages: e46185-e46185
- DOI
  10.1371/journal.pone.0046185
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390175, KAKENHI-PLANNED-22110005
[Journal Article] Perspectives on molecular targeted therapies and clinical trials for neurodegenerative diseases2012
- Author(s)
  Katsuno M, Tanaka F, Sobue G
- Journal Title
  
  J Neurol Neurosurg Psychiatry
  
  Volume: 83 Issue: 3 Pages: 329-335
- DOI
  10.1136/jnnp-2011-301307
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229011, KAKENHI-PLANNED-22110005, KAKENHI-PROJECT-23390230, KAKENHI-PROJECT-24659428
[Journal Article] Current status of treatment of spinal and bulbar muscular atrophy2012
- Author(s)
  Tanaka F, Katsuno M, Banno H, Suzuki K, Adachi H, Sobue G
- Journal Title
  
  Neural Plast
  
  Volume: 2012 Pages: 369284-369284
- DOI
  10.1155/2012/369284
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229011, KAKENHI-PROJECT-23790986, KAKENHI-PROJECT-24659428
[Journal Article] Molecular pathophysiology and disease-Modifying therapies for spinal and bulbar muscular atrophy2012
- Author(s)
  Katsuno M, Banno H, Suzuki K, Adachi H, Tanaka F, Sobue G
- Journal Title
  
  Arch Neurol
  
  Volume: 69 Issue: 4 Pages: 436-440
- DOI
  10.1001/archneurol.2011.2308
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229011, KAKENHI-PLANNED-22110005, KAKENHI-PROJECT-23390230, KAKENHI-PROJECT-23790986, KAKENHI-PROJECT-24659428
[Journal Article] Transforming growth factor-β signaling in motor neuron diseases.2011
- Author(s)
  Katsuno M, Adachi H, Banno H, Suzuki K, Tanaka F, Sobue G.
- Journal Title
  
  Current Mol Med.
  
  Volume: 11 Pages: 48-56
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229011
[Journal Article] Suppression of Alzheimer's disease-related phenotypes by expression of heat shock protein 70 in mice.2011
- Author(s)
  Hoshino T, Murao N, Namba T, Takehara M, Adachi H, Katsuno M, Sobue G, Matsushima T, Suzuki T, Mizushima T.
- Journal Title
  
  J Neurosci.
  
  Volume: 31 Issue: 14 Pages: 5225-5234
- DOI
  10.1523/jneurosci.5478-10.2011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229011, KAKENHI-PROJECT-22659011, KAKENHI-PUBLICLY-23113701, KAKENHI-PROJECT-23390017
[Journal Article] Transforming Growth Factor-β Signaling in Motor Neuron Diseases.2011
- Author(s)
  Katsuno M, Adachi H, Banno H, Suzuki K, Tanaka F, Sobue G.
- Journal Title
  
  Curr Mol Med 11
  
  Pages: 48-56
- Data Source
  KAKENHI-PROJECT-20390243
[Journal Article] Suppression of Alzheimer's disease-related phenotypes by expression of heat shock protein 70 in mice.2011
- Author(s)
  Hoshino T, Murao N, Namba T, Takehara M, Adachi H, Katsuno M, Sobue G, Matsushima T, Suzuki T, Mizushima T.
- Journal Title
  
  J Neurosci31
  
  Pages: 5225-5234
- Data Source
  KAKENHI-PROJECT-20390243
[Journal Article] Macroautophagy is regulated by the UPR-mediator CHOP and accentuates the phenotype of SBMA mice2011
- Author(s)
  Yu Z, Wang AM, Adachi H, Katsuno M, Sobue G, Yue Z, Robins DM, Lieberman AP
- Journal Title
  
  PLoS Genet
  
  Volume: 7 Issue: 10 Pages: e1002321-e1002321
- DOI
  10.1371/journal.pgen.1002321
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229011, KAKENHI-PROJECT-23390230
[Journal Article] Clinical features and molecular mechanisms of spinal and bulbar muscular atrophy (SBMA).2010
- Author(s)
  Katsuno M, Banno H, Suzuki K, Adachi H, Tanaka F, Sobue G.
- Journal Title
  
  Adv Exp Med Biol 685
  
  Pages: 64-74
- Data Source
  KAKENHI-PROJECT-20390243
[Journal Article] Suppression of melanin production by expression of HSP70.2010
- Author(s)
  Hoshino T, Matsuda M, Yamashita Y, Takehara M, Fukuya M, Mineda K, Maji D, Ihn H, Adachi H, Sobue G, Funasaka Y, Mizushima T.
- Journal Title
  
  J Biol Chem 285
  
  Pages: 13254-13263
- Data Source
  KAKENHI-PROJECT-20390243
[Journal Article] Disrupted TGF-beta signaling in spinal and bulbar muscular atrophy2010
- Author(s)
  Katsuno M, Adachi H, Minamiyama M, Waza M, Doi H, Kondo N, Mizoguchi H, Nitta A, Yamada K, Banno H, Suzuki K, Tanaka F, Sobue G.
- Journal Title
  
  J Neurosci. 30
  
  Pages: 5702-5712
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229011
[Journal Article] Microarray analysis of gene expression by skeletal muscle of three mouse models of kennedy disease/spinal bulbar muscular atrophy.2010
- Author(s)
  Mo K, Razak Z, Rao P, Yu Z, Adachi H, Katsuno M, Sobue G, Lieberman AP, Westwood JT, Monks DA.
- Journal Title
  
  PLoS One
  
  Volume: 5
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22110005
[Journal Article] Clinical features and molecular mechanisms of spinal and bulbar muscular atrophy (SBMA).2010
- Author(s)
  Katsuno M, Banno H, Suzuki K, Adachi H, Tanaka F, Sobue G.
- Journal Title
  
  Adv Exp Med Biol.
  
  Volume: 685 Pages: 64-74
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229011
[Journal Article] Microarray analysis of gene expression by skeletal muscle of three mouse models of kennedy disease/spinal bulbar muscular atrophy.2010
- Author(s)
  Mo K, Razak Z, Rao P, Yu Z, Adachi H, Katsuno M, Sobue G, Lieberman AP, Westwood JT, Monks DA.
- Journal Title
  
  PLoS One
  
  Volume: 5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229011
[Journal Article] Disrupted transforming growth factor-beta signaling in spinal and bulbar muscular atrophy.2010
- Author(s)
  Katsuno M, Adachi H, Minamiyama M, Waza M, Doi H, Kondo N, Mizoguchi H, Nitta A, Yamada K, Banno H, Suzuki K, Tanaka F, Sobue G
- Journal Title
  
  J Neurosci
  
  Volume: 30 Pages: 5702-5712
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229011
[Journal Article] Prevention of ultraviolet B radiation-induced epidermal damage by expression of heat shock protein 70.2010
- Author(s)
  Matsuda M, Hoshino T, Yamashita Y, Tanaka KI, Maji D, Sato K, Adachi H, Sobue G, Ihn H, Funasaka Y, Mizushima T.
- Journal Title
  
  J Biol Chem 285
  
  Pages: 5848-5858
- Data Source
  KAKENHI-PROJECT-20390243
[Journal Article] Clinicopathological features of acute autonomic and sensory neuropathy.2010
- Author(s)
  Koike H, Atsuta N, Adachi H, Iijima M, Katsuno M, Yasuda T, Fukada Y, Yasui K, Nakashima K, Horiuchi M, Shiomi K, Fukui K, Takashima S, Morita Y, Kuniyoshi K, Hasegawa Y, Toribe Y, Kajiura M, Takeshita S, Mukai E, Sobue G.
- Journal Title
  
  Brain 133(10)
  
  Pages: 2881-2896
- NAID
  10025625514
- Data Source
  KAKENHI-PROJECT-20390243
[Journal Article] Disrupted TGF-beta signaling in spinal and bulbar muscular atrophy2010
- Author(s)
  Katsuno M, Adachi H, Minamiyama M, Waza M, Doi H, Kondo N, Mizoguchi H, Nitta A, Yamada K, Banno H, Suzuki K, Tanaka F, Sobue G
- Journal Title
  
  J Neurosci
  
  Volume: 30 Issue: 16 Pages: 5702-5712
- DOI
  10.1523/jneurosci.0388-10.2010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229011
[Journal Article] Disrupted transforming growth factor-beta signaling in spinal and bulbar muscular atrophy.2010
- Author(s)
  Katsuno M, Adachi H, Minamiyama M, Waza M, Doi H, Kondo N, Mizoguchi H, Nitta A, Yamada K, Banno H, Suzuki K, Tanaka F, Sobue G.
- Journal Title
  
  J Neurosci 30
  
  Pages: 5702-5712
- Data Source
  KAKENHI-PROJECT-20390243
[Journal Article] Microarray Analysis of Gene Expression by Skeletal Muscle of Three Mouse Models of Kennedy Disease/Spinal Bulbar Muscular Atrophy.2010
- Author(s)
  Mo K, Razak Z, Rao Y, Yu Z, Adachi H, Katsuno M, Sobue G, Lieberman AP, Westwood JT, Monks DA.
- Journal Title
  
  PLoS ONE 5
  
  Pages: 12922-12922
- Data Source
  KAKENHI-PROJECT-20390243
[Journal Article] Transforming growth factor-beta signaling in motor neuron diseases.2010
- Author(s)
  Katsuno M, Adachi H, Banno H, Suzuki K, Tanaka F, Sobue G.
- Journal Title
  
  Current Mol Med.
  
  Volume: 11 Pages: 48-56
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22110005
[Journal Article] Dorfin ameliorates phenotypes in a transgenic mouse model of amyotrophic lateral sclerosis.2010
- Author(s)
  Sone J, Niwa J, Kawai K, Ishigaki S, Yamada S, Adachi H, Katsuno M, Tanaka F, Doyu M, Sobue G.
- Journal Title
  
  J Neurosci Res 88
  
  Pages: 123-135
- Data Source
  KAKENHI-PROJECT-20390243
[Journal Article] Disrupted TGF-beta signaling in spinal and bulbar muscular atrophy.2010
- Author(s)
  Katsuno M, Adachi H, Minamiyama M, Waza M, Doi H, Kondo N, Mizoguchi H, Nitta A, Yamada K, Banno H, Suzuki K, Tanaka F, Sobue G.
- Journal Title
  
  J Neurosci.
  
  Volume: 30 Pages: 5702-5707
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22110005
[Journal Article] Dorfin ameliorates phenotypes in a transgenic mouse model of amyotrophic lateral sclerosis2010
- Author(s)
  Sone J, Niwa JI, Kawai K, Ishigaki S, Yamada SI, Adachi H, Katsuno M, Tanaka F, Doyu M, Sobue G.
- Journal Title
  
  J Neurosci Res. 88
  
  Pages: 123-135
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229011
[Journal Article] The case for cholesterol2009
- Author(s)
  Katsuno M, Adachi H, Sobue G.
- Journal Title
  
  .Nature Med. (in press)
- Data Source
  KAKENHI-PROJECT-19390238
[Journal Article] Phase 2 trial of leuprorelin in patients with spinal and bulbar muscular atrophy.2009
- Author(s)
  Banno H, Katsuno M, Suzuki K, Takeuchi Y, Kawashima M, Suga N, Takamori M, Ito M, Nakamura T, Matsuo K, Yamada S, Oki Y, Adachi H, Minamiyama M, Waza M, Atsuta N, Watanabe H, Fujimoto Y, Nakashima T, Tanaka F, Doyu M, Sobue G.
- Journal Title
  
  Ann Neurol 65
  
  Pages: 140-150
- Data Source
  KAKENHI-PROJECT-20390243
[Journal Article] 17-DMAG ameliorates polyglutamine-mediated motor neuron degeneration through well-preserved proteasome function in a SBMA model mouse.2009
- Author(s)
  Tokui K*, Adachi H*, Waza M, Katsuno M, Minamiyama M, Doi H, Tanaka K, Hamazaki J, Murata S, Tanaka F, Sobue G.
- Journal Title
  
  Hum Mol Genet(* Evenly contributed to the study) 18
  
  Pages: 898-910
- Data Source
  KAKENHI-PROJECT-20390243
[Journal Article] HSP70 Confers Protection against Indomethacin-Induced Lesions of the Small Intestine.2009
- Author(s)
  Teita A, Tanaka KI, Yamakawa N, Adachi H, Sobue G, Goto H, Takeuchi K, Mizushima T.
- Journal Title
  
  J Pharmacol Exp Ther 330
  
  Pages: 458-467
- Data Source
  KAKENHI-PROJECT-20390243
[Journal Article] A role for HSP70 in protecting against indomethacin-induced gastric lesions.2009
- Author(s)
  Suemasu S, Tanaka KI, Namba T, Ishihara T, Katsu T, Fujimoto M, Adachi H, Sobue G, Takeuchi K, Nakai A, Mizushima T.
- Journal Title
  
  J Biol Chem 284
  
  Pages: 19705-19715
- Data Source
  KAKENHI-PROJECT-20390243
[Journal Article] TDP-43 depletion induces neuronal cell damage through dysregulation of Rho family GTPases.2009
- Author(s)
  Iguchi Y, Katsuno M, Niwa JI, Yamada SI, Sone J, Waza M, Adachi H, Tanaka F, Nagata KI, Arimura N, Watanabe T, Kaibuchi K, Sobue G.
- Journal Title
  
  J Biol Chem 284
  
  Pages: 22059-22066
- Data Source
  KAKENHI-PROJECT-20390243
[Journal Article] Heat shock proteins in neurodegenerative diseases : pathogenic roles and therapeutic implications.2009
- Author(s)
  Adachi H, Katsuno M, Waza M, Minamiyama M, Tanaka F, Sobue G.
- Journal Title
  
  Int J Hyperthermia 25
  
  Pages: 647-654
- Data Source
  KAKENHI-PROJECT-20390243
[Journal Article] Getting a handle on Huntington's disease : the case for cholesterol.2009
- Author(s)
  Katsuno M, Adachi H, Sobue G.
- Journal Title
  
  Nat Med 15
  
  Pages: 253-254
- Data Source
  KAKENHI-PROJECT-20390243
[Journal Article] 17-DMAG ameliorates polyglutamine-mediated motor neuron degeneration through well-preserved proteasome function in an SBMA model mouse2009
- Author(s)
  Tokui K, Adachi H, Waza M, Katsuno M, Minamiyama M, Doi H, Tanaka K, Hamazaki J, Murata S, Tanaka F, Sobue G.
- Journal Title
  
  Hum Mol Genet 18
  
  Pages: 898-910
- Data Source
  KAKENHI-PROJECT-19390238
[Journal Article] Heat shock proteins in neurodegenerative diseases : Pathogenic roles and therapeutic implications2009
- Author(s)
  Adachi H, Katsuno M, Waza M, Minamiyama M, Tanaka F, Sobue G.
- Journal Title
  
  Int J Hyperthermia 25
  
  Pages: 647-654
- Data Source
  KAKENHI-PROJECT-21229011
[Journal Article] TDP-43 Depletion Induces Neuronal Cell Damage through Dysregulation of Rho Family GTPases2009
- Author(s)
  Iguchi Y, Katsuno M, Niwa J, Yamada S, Sone J, Waza M, Adachi H, Tanaka F, Nagata K, Arimura N, Watanabe T, Kaibuchi K, Sobue G.
- Journal Title
  
  J Biol Chem. 284
  
  Pages: 22059-22066
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229011
[Journal Article] Overexpression of IGF-1 in muscle attenuates disease in a mouse model of spinal and bulbar muscular atrophy.2009
- Author(s)
  Palazzolo I, Stack C, Kong L, Musaro A, Adachi H, Katsuno M, Sobue G, Taylor JP, Sumner CJ, Fischbeck KH, Pennuto M.
- Journal Title
  
  Neuron 63
  
  Pages: 316-328
- Data Source
  KAKENHI-PROJECT-20390243
[Journal Article] Overexpression of IGF-1 in muscle attenuates disease in a mouse model of spina I and bulbar muscular atrophy2009
- Author(s)
  Palazzolo I, Stack C, Kong L, Musaro A, Adachi H, Katsuno M, Sobue G, Taylor JP, Sumner CJ, Fischbeck KH, Pennuto M.
- Journal Title
  
  Neuron 63
  
  Pages: 316-328
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229011
[Journal Article] Phase 2 trial of leuprorelin in patients with spinal and bulbar muscular atrophy2009
- Author(s)
  Banno H, Katsuno M, Suzuki K, Takeuchi Y, Kawashima M, Suga N, Takamori M, Ito M, Nakamura T, Matsuo K, Yamada S, Oki Y, Adachi H, Minamiyama M, Waza M, Atsuta N, Watanabe H, Fujimoto Y, Nakashima T, Tanaka F, Doyu M, Sobue G
- Journal Title
  
  Ann. Neurol 65
  
  Pages: 140-150
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209033
[Journal Article] 17-DMAG ameliorates polyglutamine-mediated motor neuron degeneration through well-preserved proteasome function in a SBMA model mouse2009
- Author(s)
  Tokui K, Adachi H, Waza M, Katsuno M, Minamiyama M, Doi H, Tanaka K, Hamazaki J, Murata S, Tanaka F, Sobue G
- Journal Title
  
  Hum. Mol. Genet 18
  
  Pages: 898-910
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209033
[Journal Article] Getting a handle on Huntington's disease : the case for cholesterol2009
- Author(s)
  Katsuno M, Adachi H, Sobue G
- Journal Title
  
  Nat. Med 15
  
  Pages: 253-254
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209033
[Journal Article] Phase 2 trial of leuprorelin in patients with spinal and bulbar muscular atrophy2009
- Author(s)
  Banno H, Katsuno M, Suzuki K, Takeuchi Y, Kawashima M, Suga N, Takamori M, Ito M, Nakamura T, Matsuo K, Yamada S, Oki Y, Adachi H, Minamiyama M, Waza M, Atsuta N, Watanabe H, Fujimoto Y, Nakashima T, Tanaka F, Doyu M, Sobue G.
- Journal Title
  
  Ann Neurol. 65
  
  Pages: 140-150
- Data Source
  KAKENHI-PROJECT-19390238
[Journal Article] Molecular Genetics and Biomarkers of Polyglutamine Diseases2008
- Author(s)
  Katsuno M, Banno H, Suzuki K, Takeuchi Y, Kawashima M, Adachi H, Tanaka F, Sobue G
- Journal Title
  
  Current Mol. Med. 8
  
  Pages: 221-234
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209033
[Journal Article] Molecular genetics and biomarkers of polyglutamine diseases2008
- Author(s)
  Katsuno M, Banno H, Suzuki K, Takeuchi Y, Kawashima M, Tanaka F, Adachi H, Sobue G.
- Journal Title
  
  Curr Mol Med. 8
  
  Pages: 221-234
- Data Source
  KAKENHI-PROJECT-19390238
[Journal Article] Therapeutic strategies for spinal and bulbar muscular atrophy (SBMA)2007
- Author(s)
  Katsuno M, Banno H, Suzuki K, Takeuchi Y, Minamiyama M, Waza M, Adachi H, Tanaka F, Sobue G
- Journal Title
  
  Drug Future 32
  
  Pages: 907-917
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209033
[Journal Article] Gene Expressions Specifically Detected in Motor Neurons (Dynactin, 1, Early Growth Response 3, Acetyl-CoA Transporter, Death Receptor 5, and Cyclin C) Differentially Correlate to Pathologic Markers in Sporadic Amyotrophic Lateral Sclerosis2007
- Author(s)
  Jiang, YM, Yamamoto, M, Tanaka, F, Ishigaki, S, Katsuno, M, Adachi, H, Doyu M, Yoshida, M, Hashizume, Y, Sobue, G
- Journal Title
  
  J Neuropathol Exp Neurol 66
  
  Pages: 617-627
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18599002
[Journal Article] CHIP overexpression reduces the mutant AR protein and amelio rates phenotypes of the spinal and bulbar muscular atrophy transgenic mouse model.2007
- Author(s)
  Adachi H, et. al.
- Journal Title
  
  J Neurosci 27
  
  Pages: 5115-5126
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18599002
[Journal Article] Pathogenesis and molecular targeted therapy of spinal and bulbar muscular atrophy2007
- Author(s)
  Adachi, H, Waza, M, Katsuno, M, Tanaka, F, Doyu, M, Sobue, G
- Journal Title
  
  Neuropathol Appl Neurobiol 33
  
  Pages: 135-151
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18599002
[Journal Article] CHIP overexpression reduces mutant androgen receptor protein and ameliorates phenotypes of the spinal and bulbar muscular atrophy transgenic mouse model2007
- Author(s)
  Adachi H, Waza M, Tokui K, Katsuno M, Minamiyama M, Tanaka F, Doyu M, Sobue G.
- Journal Title
  
  J Neurosci 27
  
  Pages: 5115-5126
- Data Source
  KAKENHI-PROJECT-19390238
[Journal Article] CHIP Overexpression Reduces Mutant Androgen Receptor Protein and Ameliorates Phenotypes of the Spinal and Bulbar Muscular Atrophy Transgenic Mouse Model2007
- Author(s)
  Adachi H, Waza M, Tokui K, Katsuno M, Minamiyama M, Tanaka F, Doyu M, Sobue G
- Journal Title
  
  J. Neurosci 27
  
  Pages: 5115-5126
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209033
[Journal Article] Pathogenesis and molecular targeted therapy of spinal and bulbar muscular atrophy2007
- Author(s)
  Adachi H, Waza M, Katsuno M, Tanaka F, Doyu M, Sobue G
- Journal Title
  
  Neuropathol Appl Neurobiol 33
  
  Pages: 135-151
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209033
[Journal Article] Therapeutic strategies for spinal and bulbar musculara atrophy (SBMA)2007
- Author(s)
  Katsuno M, Bannno H, Suzuki K, Takeuchi Y, Minamiyama M, Waza M, Adachi H, Tanaka F, Sobue G
- Journal Title
  
  Drugns of the Future 32
  
  Pages: 907-917
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209033
[Journal Article] CHIP overexpression reduces the mutant AR protein and ameliorates phenotypes of the spinal and bulbar muscular atrophy transgenic mouse model2007
- Author(s)
  Adachi, H, Waza, M, Tokui, K, Katsuno, M, Minamiyama, M, Tanaka, F, Doyu, M, Sobue, G
- Journal Title
  
  J Neurosci 27
  
  Pages: 5115-5126
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18599002
[Journal Article] CHIP overexpression reduces mutant androgen receptor protein and ameliorates phenotypes of the spinal and bulbar muscular atrphy transgenic mouse model2007
- Author(s)
  Adachi H, et. al.
- Journal Title
  
  J Neurosci 27
  
  Pages: 5115-5126
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390238
[Journal Article] Gene expressions specifically detected in motor neurons (dynactin l, early growth response 3, Acetyl-CoA transporter, death receptor 5, and cyclin C) differentially correlate to athologic markers in sporadic amyotrophic lateral sclerosis2007
- Author(s)
  Jiang Y, Yamamoto M, Tanaka F, Ishigaki S, Katsuno M, Adachi H, Niwia J, Doyu M, Yoshida M, Hashizume Y, Sobue G
- Journal Title
  
  Neuropathol Exp Neurol 66
  
  Pages: 617-627
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209033
[Journal Article] Pathogenesis and molecular targeted therapy of spinal and bulbar muscular atrophy2007
- Author(s)
  Adachi H, Waza M, Katsuno M, Tanaka F, Doyu M, Sobue G.
- Journal Title
  
  Neuropathol Appl Neurobiol 33
  
  Pages: 135-151
- Data Source
  KAKENHI-PROJECT-19390238
[Journal Article] Genetic evidence for a protective role for heat shock factor l and heat shock protein 70 against colitis2007
- Author(s)
  Tanaka K, Namba T, Arai Y, Fujimoto M, Adachi H, Sobue G, Takeuchi K, Nakai A, Mizushima T
- Journal Title
  
  J Biol Chem 282
  
  Pages: 23240-23252
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209033
[Journal Article] Pathogenesis and molecular targeted therapy of spinal and bulbar muscular atrophy.2007
- Author(s)
  Adachi H, et. al.
- Journal Title
  
  Neuropathol Appl Neurobiol 33
  
  Pages: 135-151
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18599002
[Journal Article] Pathogenesis and molecular targeted therapy of spinal and bulbar muscular atrophy2007
- Author(s)
  Adachi H, Waza M, Katsuno M, Tanaka F, Doyu M, Sobue G
- Journal Title
  
  Neuropathol. Appl. Neurobiol 33
  
  Pages: 135-151
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209033
[Journal Article] Reduces Mutant Androgen Receptor Protein and Ameliorates Phenotypes of the Spinal and Bulbar Muscular Atrophy Transgenic Mouse Model2007
- Author(s)
  Adachi H, Waza M, Tokui K, Katsuno M, Minamiyama M, Tanak F, Doyu M, Sobue G
- Journal Title
  
  J Neurosci 27
  
  Pages: 5115-5126
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209033
[Journal Article] Gene expressions specifically detected in motor neurons (dynactin 1, early growth response 3, acetyl-CoA transporter, death receptor 5, and cyclin C) differentially correlate to pathologic markers in sporadic amyotrophic lateral sclerosis2007
- Author(s)
  Jiang YM, Yamamoto M, Tanaka F, Ishigaki S, Katsuno M, Adachi H, Niwa J, Doyu M, Yoshida M, Hashizume Y, Sobue G.
- Journal Title
  
  J Neuropathol Exp Neurol 66
  
  Pages: 617-627
- Data Source
  KAKENHI-PROJECT-19390238
[Journal Article] 臨床医のための神経病理球脊髄性筋萎縮症2006
- Author(s)
  足立弘明
- Journal Title
  
  Clinical Neuroscience 24
  
  Pages: 974-975
- Data Source
  KAKENHI-PROJECT-18599002
[Presentation] COVID-19感染による神経障害2021
- Author(s)
  足立弘明
- Organizer
  第70回九州支部生涯教育講演会
- Invited
- Data Source
  KAKENHI-PROJECT-19K07970
[Presentation] TFEB over-expression reduces mutant AR protein and ameliorates phenotypes of the SBMA transgenic mouse model2021
- Author(s)
  Hiroaki Adachi, Zhe Huang, Kazumasa Okada, Keiko Ohnari, Tomoyo Hashimoto, Tomoko Toyota, Yukio Iwanaka
- Organizer
  第62回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-19K07970
[Presentation] Perampanel improves the epilepsy phenotype by the phosphorylation of GluA1 in the DRPLA transgenic mice2021
- Author(s)
  Tomoko Toyota, Zhe Huang, Kazumasa Okada, Toshiya Sato, Shoji Tsuji, Hiroaki Adachi
- Organizer
  第62回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-19K07970
[Presentation] Effects of the overexpression of TFEB in cellular and mouse models of spinal and bulbar muscular atrophy2020
- Author(s)
  Hiroaki Adachi, Zhe Huang, Qiang Qiang, Kazumasa Okada, Keiko Ohnari, Tomoyo Hashimoto, Tomoko Toyota, Yukio Iwanaka
- Organizer
  第43回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-19K07970
[Presentation] Effects of the overexpression of TFEB in cellullar and mouse models of neurodegenerarive diseases.2020
- Author(s)
  Hiroaki Adachi, Zhe Huang, Qiang Qiang, Kazumasa Okada, Keiko Ohnari, Tomoyo Hashimoto, Tomoko Toyota, Yukio Iwanaka
- Organizer
  第61回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-19K07970
[Presentation] Defects in muscle ion channels contribute to motor dysfunction in spinal and bulbar muscular atrophy.2019
- Author(s)
  Xu Y, Katsuno M, Adachi H, Sobue G, Breedlove SM, Jordan CL.
- Organizer
  Neuroscience 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07970
[Presentation] Dynactin-1 implicates autophagosome-lysosome fusion defects in the pathogenesis of neurodegenerative diseases2019
- Author(s)
  Adachi H
- Organizer
  Neuroscience 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05708
[Presentation] Dynactin-1 implicates autophagosome-lysosome fusion defects in the neurodegenerative diseases.2019
- Author(s)
  足立弘明, 黄哲, 岡田和将, 大成圭子, 橋本智代, 豊田知子, 岩中行己男
- Organizer
  第60回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-19K07970
[Presentation] Perampanel administration to the Q129 and Q113 DRPLA transgenic mice.2019
- Author(s)
  Toyota T, Huang Z, Okada K, Sato T, Tsuji S, Adachi H.
- Organizer
  第60回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-19K07970
[Presentation] Dynactin-1 and TRAPPC9 implicates autophagosome-lysosome fusion defects in the pathogenesis of neurodegenerative diseases.2019
- Author(s)
  Hiroaki Adachi, Zhe Huang, Kazumasa Okada, Keiko Ohnari, Tomoyo Hashimoto, Tomoko Toyota
- Organizer
  第42回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-19K07970
[Presentation] Dynactin-1 and TRAPPC9 implicate autophagosome-lysosome fusion in the pathogenesis of neurodegenerative diseases.2019
- Author(s)
  Adachi H, Huang Z, Okada K, Ohnari K, Hashimoto T, Toyota T, Iwanaka Y.
- Organizer
  Neuroscience 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07970
[Presentation] オートファジーによる神経変性疾患の病因蛋白質の分解とその治療への応用2018
- Author(s)
  足立弘明
- Organizer
  臨床ストレス応答学会
- Data Source
  KAKENHI-PUBLICLY-17H05708
[Presentation] Induction of autophagy enhances degradation of causative proteins in cellular models of neurodegenerative diseases.2017
- Author(s)
  Adachi H
- Organizer
  Neuroscience 2017
- Data Source
  KAKENHI-PUBLICLY-17H05708
[Presentation] Effects of Quercetin in cellular models of neurodegenerative diseases.2017
- Author(s)
  Adachi H
- Organizer
  第40回神経科学大会
- Data Source
  KAKENHI-PUBLICLY-17H05708
[Presentation] Effects of induction of autophagy in cellular models of neurodegenerative diseases.2017
- Author(s)
  Adachi H
- Organizer
  The XXIII World Congress of Neurology
- Data Source
  KAKENHI-PUBLICLY-17H05708
[Presentation] Effects of the overexpression of TFEB in cellular models of neurodegenerative diseases2016
- Author(s)
  Adachi H, Huang Z, Okada K, Ohnari K, Hashimoto T, Toyota T, Iwanakan Y
- Organizer
  第39回日本神経科学大会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2016-07-20
- Data Source
  KAKENHI-PROJECT-26293207
[Presentation] Effects of the overexpression of TFEB in cellular models of neurodegenerative diseases2016
- Author(s)
  足立弘明
- Organizer
  第57回日本神経学会学術大会
- Place of Presentation
  神戸国際会議場（兵庫県神戸市）
- Year and Date
  2016-05-18
- Data Source
  KAKENHI-PROJECT-26293207
[Presentation] TFEB and Hikeshi influence the degradation of the disease-causative proteins in cellular models of neurodegenerative diseases.2016
- Author(s)
  Adachi H, Huang Z, Okada K, Ohnari K, Hashimoto T, Toyota T, Iwanakan Y, Sobue G.
- Organizer
  Neuroscience 2016
- Place of Presentation
  San Diego（米国）
- Year and Date
  2016-11-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293207
[Presentation] オートファジーによる変異アンドロゲン受容体の分解とその治療への応用2016
- Author(s)
  足立弘明、黄哲、岡田和将、大成圭子、橋本智代、岩中行己男、豊田知子、勝又竜
- Organizer
  第11回　臨床ストレス応答学会大会
- Place of Presentation
  山口大学（山口県・山口市）
- Year and Date
  2016-11-11
- Data Source
  KAKENHI-PROJECT-26293207
[Presentation] 神経変性疾患モデルにおけるTFEB高発現の効果2016
- Author(s)
  足立弘明
- Organizer
  第39回日本神経科学大会
- Place of Presentation
  パシフィコ横浜 (神奈川県横浜市)
- Year and Date
  2016-07-20
- Data Source
  KAKENHI-PROJECT-26293207
[Presentation] Effects of the overexpression of TFEB in cellular models of neurodegenerative diseases2016
- Author(s)
  Adachi H, Huang Z, Okada K, Ohnari K, Hashimoto T, Toyota T, Iwanakan Y
- Organizer
  第57回日本神経学会学術大会
- Place of Presentation
  神戸国際会議場（兵庫県・神戸市）
- Year and Date
  2016-05-18
- Data Source
  KAKENHI-PROJECT-26293207
[Presentation] Increased BDNF expression in muscle slows disease in a mouse model of spinal bulbar muscular atrophy.2016
- Author(s)
  Halievski K, Katsuno M, Adachi H, Sobue G, Breedlove SM, Jordan CL.
- Organizer
  Neuroscience 2016
- Place of Presentation
  San Diego（米国）
- Year and Date
  2016-11-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293207
[Presentation] Early and androgen-dependent loss of neuromuscular transmission in two SBMA mouse models.2016
- Author(s)
  Xu Y, Atchison WD, S. Adachi H, Katsuno M, Sobue G,Breedlove SM, Jordan CL.
- Organizer
  Neuroscience 2016
- Place of Presentation
  San Diego（米国）
- Year and Date
  2016-11-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293207
[Presentation] The enhancement of protein degradation via autophagy in neurodegeneration2015
- Author(s)
  足立弘明
- Organizer
  第56回日本神経学会学術大会
- Place of Presentation
  朱鷺メッセ（新潟県新潟市）
- Year and Date
  2015-05-20
- Data Source
  KAKENHI-PROJECT-26293207
[Presentation] 神経変性疾患におけるオートファジーの利用による病因蛋白質の分解2015
- Author(s)
  足立弘明
- Organizer
  第38回日本神経科学大会
- Place of Presentation
  神戸国際会議場（兵庫県神戸市）
- Year and Date
  2015-07-28
- Data Source
  KAKENHI-PROJECT-26293207
[Presentation] 蛋白質分解システムの強化による球脊髄性筋萎縮症の病態の改善2015
- Author(s)
  足立弘明
- Organizer
  第57回日本小児神経学会
- Place of Presentation
  帝国ホテル大阪（大阪府大阪市）
- Year and Date
  2015-05-28
- Data Source
  KAKENHI-PROJECT-26293207
[Presentation] Deficits in brain-derived neurotrophic factor may underlie motor dysfunction in spinal bulbar muscular atrophy.2013
- Author(s)
  Hlievski, K., Henley, C.L., Fu, M., Katsuno, M., Adachi, H., Sobue, G., Breedlove, S.M., Jordan, C.L.
- Organizer
  Neuroscience 2013
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PLANNED-22110005
[Presentation] Genistein, a natural product derived from soybeans, ameliorates polyglutamine-mediated motor neuron disease.2013
- Author(s)
  Adachi, H., Qiang, Q., Hunag, Z., Jinag, Y.M., Katsuno, M., Kondo, N., Miyazaki, Y., Iida, M., Tohnai, G., Nakatsuji, H., Sobue, G.
- Organizer
  Neuroscience 2013
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-23390230
[Presentation] Genistein, a natural product derived from soybeans, ameliorates polyglutamine-mediated motor neuron disease.2013
- Author(s)
  Adachi, H., Qiang, Q., Hunag, Z., Jinag, Y.M., Katsuno, M., Kondo, N., Miyazaki, Y., Iida, M., Tohnai, G., Nakatsuji, H., Sobue, G.
- Organizer
  Neuroscience 2013
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-21229011
[Presentation] miR-196aはCELF2の発現抑制を介しSBMAの表現型を有意に改善する2013
- Author(s)
  宮崎雄, 足立弘明, 勝野雅央, 村松慎一, 祖父江元
- Organizer
  第54回日本神経学会総会
- Place of Presentation
  東京都千代田区 (東京国際フォーラム)
- Data Source
  KAKENHI-PROJECT-23390231
[Presentation] Genistein, a natural product derived from soybeans, ameliorates polyglutamine-mediated motor neuron disease2013
- Author(s)
  Adachi H, Qiang Q, Hunag Z, Jinag YM, Katsuno M, Kondo N, Miyazaki Y, Iida M, Tohnai G, Nakatsuji H, Sobue G
- Organizer
  Neuroscience 2013
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-21229011
[Presentation] Deficits in brain-derived neurotrophic factor may underlie motor dysfunction in spinal bulbar muscular atrophy.2013
- Author(s)
  Hlievski, K., Henley, C.L., Fu, M., Katsuno, M., Adachi, H., Sobue, G., Breedlove, S.M., Jordan, C.L.
- Organizer
  Neuroscience 2013
- Place of Presentation
  San Diego,USA
- Data Source
  KAKENHI-PROJECT-23390230
[Presentation] Heat shock factor-1 (Hsf-1) controls pathological lesion distribution of polyglutamine-induced motor neuron disease.2013
- Author(s)
  Kondo, N., Katsuno, M., Adachi, H., Minamiyama, M., Matsumoto, S., Nakatsuji, H., Miyazaki, Y., Iida, M., Tohnai, G., Sobue, G.
- Organizer
  The 24th International Symposium on ALS/MND
- Place of Presentation
  Milan, Italy
- Data Source
  KAKENHI-PROJECT-21229011
[Presentation] Genistein, a natural product derived from soybeans, ameliorates polyglutamine-mediated motor neuron disease2013
- Author(s)
  Adachi H, Qiang Q, Hunag Z, Jinag YM, Katsuno M, Kondo N, Miyazaki Y, Iida M, Tohnai G, Nakatsuji H, Sobue G
- Organizer
  Neuroscience 2013
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-23390230
[Presentation] miR-196aはCELF2の発現抑制を介しSBMAの表現型を有意に改善する2013
- Author(s)
  宮崎雄, 足立弘明 , 勝野雅央, 村松慎一, 祖父江元
- Organizer
  第54回日本神経学会総会, 東京都千代田区
- Place of Presentation
  東京国際フォーラム
- Year and Date
  2013-05-31
- Data Source
  KAKENHI-PROJECT-23390231
[Presentation] Genistein, a natural product derived from soybeans2013
- Author(s)
  Adachi H, Qiang Q, Hunag Z, Jinag YM, Katsuno M, Kondo N, Miyazaki Y, Iida M, Tohnai G, Nakatsuji H, Sobue G.
- Organizer
  ameliorates polyglutamine-mediated motor neuron disease. Neuroscience 2013
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-24659428
[Presentation] Genistein, a natural product derived from soybeans, ameliorates polyglutamine-mediated motor neuron disease.2013
- Author(s)
  Adachi H, Qiang Q, Hunag Z, Jinag YM, Katsuno M, Kondo N, Miyazaki Y, Iida M, Tohnai G, Nakatsuji H, Sobue G.
- Organizer
  Neuroscience 2013
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-24659428
[Presentation] Deficits in brain-derived neurotrophic factor may underlie motor dysfunction in spinal bulbar muscular atrophy.2013
- Author(s)
  Hlievski, K., Henley, C.L., Fu, M., Katsuno, M., Adachi, H., Sobue, G., Breedlove, S.M., Jordan, C.L.
- Organizer
  Neuroscience 2013
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-21229011
[Presentation] Deficits in brain-derived neurotrophic factor may underlie motor dysfunction in spinal bulbar muscular atrophy.2013
- Author(s)
  Hlievski K, Henley CL, Fu M, Katsuno M, Adachi H, Sobue G, Breedlove SM, Jordan CL.
- Organizer
  Neuroscience 2013
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-24659428
[Presentation] Heat shock factor-1 (Hsf-1) controls pathological lesion distribution of polyglutamine-induced motor neuron disease.2013
- Author(s)
  Kondo, N., Katsuno, M., Adachi, H., Minamiyama, M., Matsumoto, S., Nakatsuji, H., Miyazaki, Y., Iida, M., Tohnai, G., Sobue, G.
- Organizer
  The 24th International Symposium on ALS/MND
- Place of Presentation
  Milan, Italy
- Data Source
  KAKENHI-PLANNED-22110005
[Presentation] Genistein, a natural product derived from soybeans, ameliorates polyglutamine-mediated motor neuron disease.2013
- Author(s)
  Adachi, H., Qiang, Q., Hunag, Z., Jinag, Y.M., Katsuno, M., Kondo, N., Miyazaki, Y., Iida, M., Tohnai, G., Nakatsuji, H., Sobue, G.
- Organizer
  Neuroscience 2013
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PLANNED-22110005
[Presentation] Heat shock factor-1 (Hsf-1) controls pathological lesion distribution of polyglutamine-induced motor neuron disease.2013
- Author(s)
  Kondo, N., Katsuno, M., Adachi, H., Minamiyama, M., Matsumoto, S., Nakatsuji, H., Miyazaki, Y., Iida, M., Tohnai, G., Sobue, G.
- Organizer
  The 24th International Symposium on ALS/MND
- Place of Presentation
  Milan, Italy
- Data Source
  KAKENHI-PROJECT-23390230
[Presentation] Naratriptan ameliorates SBMA pathology by the repression of CGRP1-activated JNK pathway.2012
- Author(s)
  Minamiyama, M., Katsuno, M., Adachi, H., Doi, H., Kondo, N., Iida, M., Ishigaki, S., Fujioka, Y., Matsumoto, S., Miyazaki, Y., Tanaka, F., Kurihara, H., Sobue, G.
- Organizer
  Neuroscience 2012.
- Place of Presentation
  New Orleans, USA
- Data Source
  KAKENHI-PROJECT-21229011
[Presentation] Muscle dysfunction may underlie androgen-dependent motor dysfunction in two mouse models of SBMA.2012
- Author(s)
  Oki K, Adachi H, Katsuno M, Breedlove M, Sobue G. Wiseman RW, Jordan CL.
- Organizer
  Neuroscience 2012
- Place of Presentation
  New Orleans, USA
- Data Source
  KAKENHI-PROJECT-24659428
[Presentation] Molecular pathogenesis and therapy of polyglutamine-induced motor neuron degeneration2012
- Author(s)
  Katsuno M, Adachi H, Minamiyama M, Doi H, Kondo N, Miyazaki Y, Iida M, Tanaka F, Sobue G.
- Organizer
  35th Annual Meeting of the Japan Neuroscience Society
- Place of Presentation
  Nagoya Congress Center, Nagoya City, Japan
- Year and Date
  2012-09-21
- Data Source
  KAKENHI-PROJECT-24659428
[Presentation] miR-196aはSBMAにおいて異常ARmRNAの不安定化を促進し表現型を有意に改善させる2012
- Author(s)
  宮崎雄, 足立弘明, 勝野雅央, 南山誠, 蒋月梅, 土井英樹, 松本慎二郎, 近藤直英, 飯田円, 藤内玄規, 田中章景, 村松慎一, 祖父江元
- Organizer
  第53回日本神経学会総会
- Place of Presentation
  東京千代田区(東京国際フォーラム)
- Year and Date
  2012-05-24
- Data Source
  KAKENHI-PROJECT-23390231
[Presentation] Naratriptan ameliorates SBMA pathology by the repression of CGRP1-activated JNK pathway2012
- Author(s)
  Minamiyama M, Katsuno M, Adachi H, Doi H, Kondo N, Iida M, Ishigaki S, Fujioka Y, Matsumoto S, Miyazaki Y, Tanaka F, Kurihara H, Sobue G
- Organizer
  Neuroscience 2012
- Place of Presentation
  New Orleans, USA
- Data Source
  KAKENHI-PROJECT-23390230
[Presentation] p62/SQSTM1 removes toxic mutant androgen receptor in spinal bulbar muscular atrophy model mouse.2012
- Author(s)
  Adachi, H., Doi, H., Katsuno, M., Matsumoto, S., Kondo, N., Miyazaki, Y., Tohnai, G., Iida, M., Tanaka, F., Sobue, G.
- Organizer
  Neuroscience 2012.
- Place of Presentation
  New Orleans, USA
- Data Source
  KAKENHI-PROJECT-21229011
[Presentation] p62/SQSTM1 removes toxic mutant androgen receptor in spinal bulbar muscular atrophy model mouse2012
- Author(s)
  Adachi H, Doi H, Katsuno M, Matsumoto S, Kondo N, Miyazaki Y, Tohnai G, Iida M, Tanaka F, Sobue G.
- Organizer
  Neuroscience 2012
- Place of Presentation
  New Orleans, USA
- Data Source
  KAKENHI-PROJECT-24659428
[Presentation] Naratriptan ameliorates SBMA pathology by the repression of CGRP1-activated JNK pathway2012
- Author(s)
  Minamiyama M, Katsuno M, Adachi H, Doi H, Kondo N, Iida M, Ishigaki S, Fujioka Y, Matsumoto S, Miyazaki Y, Tanaka F, Kurihara H, Sobue G.
- Organizer
  Neuroscience 2012
- Place of Presentation
  New Orleans, USA
- Data Source
  KAKENHI-PROJECT-24659428
[Presentation] CGRP1 is the new therapeutic target for SBMA (Spinal and Bulbar Muscular Atrophy)2012
- Author(s)
  Minamiyama M, Katsuno M, Adachi H, Doi H, Kondo N, Iida M, Ishigaki S, Fujioka Y, Matsumoto S, Miyazaki Y, Tanaka F, Kurihara H, Sobue G.
- Organizer
  11th Biennial Meeting of the Asian Pacific Society for Neurochemistry
- Place of Presentation
  Kobe International Conference Center, Kobe, Japan
- Data Source
  KAKENHI-PROJECT-24659428
[Presentation] Viral delivery of miR-196a ameliorates the SBMA phenotype via the silencing of CELF2.2012
- Author(s)
  Miyazaki, Y., Adachi, H., Katsuno, M., Tanaka, F., Muramatsu, S.I., Sobue, G.
- Organizer
  Neuroscience 2012.
- Place of Presentation
  New Orleans, USA
- Data Source
  KAKENHI-PROJECT-21229011
[Presentation] Naratriptan ameliorates SBMA pathology by the repression of CGRP1-activated JNK pathway2012
- Author(s)
  Minamiyama M, Katsuno M, Adachi H, Doi H, Kondo N, Iida M, Ishigaki S, Fujioka Y, Matsumoto S, Miyazaki Y, Tanaka F, Kurihara H, Sobue G
- Organizer
  Neuroscience 2012
- Place of Presentation
  New Orleans, USA
- Data Source
  KAKENHI-PROJECT-21229011
[Presentation] Viral delivery of miR-196a ameliorates the SBMA phenotype via the silencing of CELF22012
- Author(s)
  Miyazaki Y, Adachi H, Katsuno M, Tanaka F, Muramatsu SI, Sobue G
- Organizer
  Neuroscience 2012
- Place of Presentation
  New Orleans, USA
- Data Source
  KAKENHI-PROJECT-21229011
[Presentation] Viral delivery of miR-196a ameliorates the SBMA phenotype via the silencing of CELF22012
- Author(s)
  Miyazaki Y, Adachi H, Katsuno M, Tanaka F, Muramatsu SI, Sobue G
- Organizer
  Neuroscience 2012
- Place of Presentation
  New Orleans, USA
- Data Source
  KAKENHI-PROJECT-23390230
[Presentation] Cell cycle dysregulation in motor neurons of spinal and bulbar muscular atrophy (SBMA)2012
- Author(s)
  Katsuno M, Adachi H, Kondo N, Minamiyama M, Doi H, Matsumoto S, Miyazaki Y, Iida M, Nakatsuji H, Tanaka F, Sobue G.
- Organizer
  23rd International Symposium on ALS/MND
- Place of Presentation
  Chicago, USA
- Data Source
  KAKENHI-PROJECT-24659428
[Presentation] Cell cycle dysregulation in motor neurons of spinal and bulbar muscular atrophy (SBMA).2012
- Author(s)
  Katsuno M, Adachi H, Kondo N, Minamiyama M, Doi H, Matsumoto S, Miyazaki Y, Iida M, Nakatsuji H, Tanaka F, Sobue G.
- Organizer
  23rd International Symposium on ALS/MND.
- Place of Presentation
  Chicago, USA
- Data Source
  KAKENHI-PROJECT-23390230
[Presentation] p62/SQSTM1 removes toxic mutant androgen receptor in spinal bulbar muscular atrophy model mouse2012
- Author(s)
  Adachi H, Doi H, Katsuno M, Matsumoto S, Kondo N, Miyazaki Y, Tohnai G, Iida M, Tanaka F, Sobue G
- Organizer
  Neuroscience 2012
- Place of Presentation
  New Orleans, USA
- Data Source
  KAKENHI-PROJECT-21229011
[Presentation] Cell cycle dysregulation in motor neurons of spinal and bulbar muscular atrophy (SBMA)2012
- Author(s)
  Katsuno M, Adachi H, Kondo N, Minamiyama M, Doi H, Matsumoto S, Miyazaki Y, Iida M, Nakatsuji H, Tanaka F, Sobue G
- Organizer
  23rd International Symposium on ALS/MND
- Place of Presentation
  Chicago, USA
- Data Source
  KAKENHI-PROJECT-23390230
[Presentation] Viral delivery of miR-196a ameliorates the SBMA phenotype via the silencing of CELF22012
- Author(s)
  Miyazaki Y, Adachi H, Katsuno M, Tanaka F, Muramatsu SI, Sobue G.
- Organizer
  Neuroscience 2012
- Place of Presentation
  New Orleans, USA
- Data Source
  KAKENHI-PROJECT-24659428
[Presentation] p62/SQSTM1 removes toxic mutant androgen receptor in spinal bulbar muscular atrophy model mouse2012
- Author(s)
  Adachi H, Doi H, Katsuno M, Matsumoto S, Kondo N, Miyazaki Y, Tohnai G, Iida M, Tanaka F, Sobue G
- Organizer
  Neuroscience 2012
- Place of Presentation
  New Orleans, USA
- Data Source
  KAKENHI-PROJECT-23390230
[Presentation] Naratriptan ameliorates SBMA pathology by the repression of CGRP1-activated JNK pathway.2012
- Author(s)
  Minamiyama M, Katsuno M, Adachi H, Doi H, Kondo N, Iida M, Ishigaki S, Fujioka Y, Matsumoto S, Miyazaki Y, Tanaka F, Kurihara H, Sobue G.
- Organizer
  Neuroscience 2012
- Place of Presentation
  New Orleans, USA
- Data Source
  KAKENHI-PROJECT-23390230
[Presentation] Viral delivery of miR-196a ameliorates the SBMA phenotype via the silencing of CELF22012
- Author(s)
  Miyazaki Y, Adachi H, Katsuno M, Tanaka F, Muramatsu S, Sobue G
- Organizer
  Neuroscience 2012
- Place of Presentation
  New Orleans
- Year and Date
  2012-10-16
- Data Source
  KAKENHI-PROJECT-23390231
[Presentation] Cell cycle dysregulation in motor neurons of spinal and bulbar muscular atrophy (SBMA)2012
- Author(s)
  Katsuno M, Adachi H, Kondo N, Minamiyama M, Doi H, Matsumoto S, Miyazaki Y, Iida M, Nakatsuji H, Tanaka F, Sobue G
- Organizer
  23rd International Symposium on ALS/MND
- Place of Presentation
  Chicago, USA
- Data Source
  KAKENHI-PROJECT-21229011
[Presentation] CGRP1 is the new therapeutic target for SBMA (Spinal and Bulbar Muscular Atrophy).2012
- Author(s)
  Minamiyama M, Katsuno M, Adachi H, Doi H, Kondo N, Iida M, Ishigaki S, Fujioka Y, Matsumoto S, Miyazaki Y, Tanaka F, Kurihara H, Sobue G.
- Organizer
  11th Biennial Meeting of the Asian Pacific Society for Neurochemistry.
- Place of Presentation
  神戸国際会議場（神戸）
- Data Source
  KAKENHI-PROJECT-23390230
[Presentation] Heat shock factor-1(HSF-1) influences distribution of pathogenic androgen receptor aggregations in model mouse of spinal and bulbar muscular atrophy (SBMA).2011
- Author(s)
  Kondo N, Katsuno M, Adachi H, Minamiyama M, Doi H, Matsumoto S, Miyazaki Y, Iida M, Tanaka F, Sobue G.
- Organizer
  第34回日本神経科学大会
- Place of Presentation
  パシフィコ横浜（神奈川）
- Data Source
  KAKENHI-PROJECT-21229011
[Presentation] 球脊髄性筋萎縮症モデルマウスにおける異常蛋白凝集の病理学的分布はHsf-1の影響を受ける.2011
- Author(s)
  近藤直英, 勝野雅央, 足立弘明, 南山誠, 土井英樹, 松本慎二郎, 宮崎雄, 飯田円, 田中章景, 祖父江元.
- Organizer
  第52回日本神経学会学術大会
- Place of Presentation
  名古屋国際会議場（愛知）
- Data Source
  KAKENHI-PROJECT-21229011
[Presentation] Cell cycle dysregulation in spinal and bulbar muscular atrophy (SBMA).2011
- Author(s)
  Katsuno M, Adachi H, Kondo N, Minamiyama M, Doi H, Matsumoto S-J, Miyazaki Y, Tanaka F, Sobue G.
- Organizer
  Gordon conference on CAG triplet repeat disorders
- Place of Presentation
  Il Ciocco, Italy,
- Data Source
  KAKENHI-PROJECT-21229011
[Presentation] Molecular pathology of SBMA (Spinal Bulbar Muscular Atrophy) related gene CGRP1.2011
- Author(s)
  Minamiyama M, Katsuno M, Adachi H, Doi H, Kondo N, Tanaka F, Sobue G, Kurihara H.
- Organizer
  第34回日本神経科学大会
- Place of Presentation
  パシフィコ横浜（神奈川）
- Data Source
  KAKENHI-PROJECT-21229011
[Presentation] 球脊髄性筋萎縮症モデルマウスにおける異常蛋白凝集の病理学的分布はHsf-1の影響を受ける2011
- Author(s)
  近藤直英, 勝野雅央, 足立弘明, 南山誠, 土井英樹, 松本慎二郎, 宮崎雄, 飯田円, 田中章景, 祖父江元
- Organizer
  第52回日本神経学会学術大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PLANNED-22110005
[Presentation] A peony extract enhances protein degradation systems and exerts therapeutic effects in the polyglutamine-mediated motor neuron disease2011
- Author(s)
  Adachi H, Tohnai G, Katsuno M, Minamiyama M, Doi H, Matsumoto S, Kondo N, Miyazaki Y, Tanaka F, Ohtsuka K, Sobue G
- Organizer
  Neuroscience 2011
- Place of Presentation
  Washington DC, USA
- Data Source
  KAKENHI-PROJECT-23390230
[Presentation] Cell cycle dysregulation in spinal and bulbar muscular atrophy (SBMA).2011
- Author(s)
  Katsuno M, Adachi H, Minamiyama M, Kondo N, Doi H, Matsumoto S, Miyazaki Y, Tanaka F, Sobue G.
- Organizer
  第34回日本神経科学大会
- Place of Presentation
  パシフィコ横浜（神奈川）
- Data Source
  KAKENHI-PROJECT-21229011
[Presentation] A peony extract enhances protein degradation systems and exerts therapeutic effects in the polyglutamine-mediated motor neuron disease2011
- Author(s)
  Adachi H, Tohnai G, Katsuno M, Minamiyama M, Doi H, Matsumoto S, Kondo N, Miyazaki Y, Tanaka F, Ohtsuka K, Sobue G
- Organizer
  Neuroscience 2011
- Place of Presentation
  Washington DC, USA
- Data Source
  KAKENHI-PROJECT-21229011
[Presentation] 球脊髄性筋萎縮症(SBMA)病態関連遺伝子CGRP1の分子機構2011
- Author(s)
  南山　誠, 勝野雅央, 足立弘明, 土井英樹, 近藤直英, 田中章景, 祖父江元, 栗原裕基.
- Organizer
  第52回日本神経学会学術大会
- Place of Presentation
  名古屋国際会議場（愛知）
- Data Source
  KAKENHI-PROJECT-21229011
[Presentation] Heat shock factor-1 (Hsf-1) influences distribution of pathogenic androgen receptor aggregations in model mouse of spinal and bulbar muscular atrophy (SBMA).2011
- Author(s)
  Kondo N, Katsuno M, Adachi H, Minamiyama M, Doi H, Matsumoto S-J, Miyazaki Y, Tanaka F, Sobue G.
- Organizer
  Gordon conference on CAG triplet repeat disorders
- Place of Presentation
  Il Ciocco, Italy,
- Data Source
  KAKENHI-PROJECT-21229011
[Presentation] Cell cycle dysregulation in spinal and bulbar muscular atrophy (SBMA)2011
- Author(s)
  Katsuno M, Adachi H, Kondo N, Minamiyama M, Doi H, Matsumoto S-J, Miyazaki Y, Tanaka F, Sobue G
- Organizer
  Gordon conference on CAG triplet repeat disorders
- Place of Presentation
  Il Ciocco, Italy
- Data Source
  KAKENHI-PROJECT-23390230
[Presentation] Cell cycle dysregulation in spinal and bulbar muscular atrophy (SBMA)2011
- Author(s)
  Katsuno M, Adachi H, Kondo N, Minamiyama M, Doi H, Matsumoto S-J, Miyazaki Y, Tanaka F, Sobue G
- Organizer
  Gordon conference on CAG triplet repeat disorders
- Place of Presentation
  Il Ciocco, Italy
- Data Source
  KAKENHI-PLANNED-22110005
[Presentation] Heat shock factor-1(Hsf-1) influences distribution of pathogenic androgen receptor aggregations in model mouse of spinal and bulbar muscular atrophy (SBMA)2011
- Author(s)
  Kondo N, Katsuno M, Adachi H, Minamiyama M, Doi H, Matsumoto S-J, Miyazaki Y, Tanaka F, Sobue G
- Organizer
  Gordon conference on CAG triplet repeat disorders
- Place of Presentation
  Il Ciocco, Italy
- Data Source
  KAKENHI-PROJECT-23390230
[Presentation] 球脊髄性筋萎縮症(SBMA)病態関連遺伝子CGRP1の分子機構2011
- Author(s)
  南山誠, 勝野雅央, 足立弘明, 土井英樹, 近藤直英, 田中章景, 祖父江元, 栗原裕基
- Organizer
  第52回日本神経学会学術大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23390230
[Presentation] Molecular pathology of SBMA (Spinal Bulbar Muscular Atrophy) related gene CGRP12011
- Author(s)
  Minamiyama M, Katsuno M, Adachi H, Doi H, Kondo N, Tanaka F, Sobue G, Kurihara H
- Organizer
  第34回日本神経科学大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PLANNED-22110005
[Presentation] 球脊髄性筋萎縮症における細胞周期異常2011
- Author(s)
  勝野雅央, 足立弘明, 南山誠, 土井英樹, 近藤直英, 松本慎二郎, 宮崎雄, 坂野晴彦, 鈴木啓介, 田中章景, 祖父江元
- Organizer
  第52回日本神経学会学術大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PLANNED-22110005
[Presentation] Heat shock factor-1 (HSF-1) influences distribution of pathogenic androgen receptor aggregations in model mouse of spinal and bulbar muscular atrophy (SBMA)2011
- Author(s)
  Kondo N, Katsuno M, Adachi H, Minamiyama M, Doi H, Matsumoto S, Miyazaki Y, Iida M, Tanaka F, Sobue G
- Organizer
  第34回日本神経科学大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PLANNED-22110005
[Presentation] Heat shock factor-1(Hsf-1) influences distribution of pathogenic androgen receptor aggregations in model mouse of spinal and bulbar muscular atrophy (SBMA)2011
- Author(s)
  Kondo N, Katsuno M, Adachi H, Minamiyama M, Doi H, Matsumoto S-J, Miyazaki Y, Tanaka F, Sobue G
- Organizer
  Gordon conference on CAG triplet repeat disorders
- Place of Presentation
  Il Ciocco, Italy
- Data Source
  KAKENHI-PROJECT-21229011
[Presentation] Molecular pathology of SBMA (Spinal Bulbar Muscular Atrophy) related gene CGRP12011
- Author(s)
  Minamiyama M, Katsuno M, Adachi H, Doi H, Kondo N, Tanaka F, Sobue G, Kurihara H
- Organizer
  第34回日本神経科学大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23390230
[Presentation] Heat shock factor-1(HSF-1) influences distribution of pathogenic androgen receptor aggregations in model mouse of spinal and bulbar muscular atrophy (SBMA)2011
- Author(s)
  Kondo N, Katsuno M, Adachi H, Minamiyama M, Doi H, Matsumoto S, Miyazaki Y, Iida M, Tanaka F, Sobue G
- Organizer
  第34回日本神経科学大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23390230
[Presentation] Cell cycle dysregulation in spinal and bulbar muscular atrophy (SBMA)2011
- Author(s)
  Katsuno M, Adachi H, Minamiyama M, Kondo N, Doi H, Matsumoto S, Miyazaki Y, Tanaka F, Sobue G
- Organizer
  第34回日本神経科学大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PLANNED-22110005
[Presentation] Heat shock factor-1 (Hsf-1) influences distribution of pathogenic androgen receptor aggregations in model mouse of spinal and bulbar muscular atrophy (SBMA)2011
- Author(s)
  Kondo N, Katsuno M, Adachi H, Minamiyama M, Doi H, Matsumoto S-J, Miyazaki Y, Tanaka F, Sobue G
- Organizer
  Gordon conference on CAG triplet repeat disorders
- Place of Presentation
  Il Ciocco, Italy
- Data Source
  KAKENHI-PROJECT-23390230
[Presentation] 球脊髄性筋萎縮症(SBMA)病態関連遺伝子CGRP1の分子機構2011
- Author(s)
  南山誠, 勝野雅央, 足立弘明, 土井英樹, 近藤直英, 田中章景, 祖父江元, 栗原裕基.
- Organizer
  第52回日本神経学会学術大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PLANNED-22110005
[Presentation] 球脊髄性筋萎縮症における細胞周期異常.2011
- Author(s)
  勝野雅央, 足立弘明, 南山　誠, 土井英樹, 近藤直英, 松本慎二郎, 宮崎　雄, 坂野晴彦, 鈴木啓介, 田中章景, 祖父江元.
- Organizer
  第52回日本神経学会学術大会
- Place of Presentation
  名古屋国際会議場（愛知）
- Data Source
  KAKENHI-PROJECT-21229011
[Presentation] Cell cycle dysregulation in spinal and bulbar muscular atrophy (SBMA)2011
- Author(s)
  Katsuno M, Adachi H, Kondo N, Minamiyama M, Doi H, Matsumoto S-J, Miyazaki Y, Tanaka F, Sobue G
- Organizer
  Gordon conference on CAG triplet repeat disorders
- Place of Presentation
  Il Ciocco, Italy
- Data Source
  KAKENHI-PROJECT-21229011
[Presentation] Heat shock factor-1 (Hsf-1) influences distribution of pathogenic androgen receptor aggregations in model mouse of spinal and bulbar muscular atrophy (SBMA)2011
- Author(s)
  Kondo N, Katsuno M, Adachi H, Minamiyama M, Doi H, Matsumoto S-J, Miyazaki Y, Tanaka F, Sobue G
- Organizer
  Gordon conference on CAG triplet repeat disorders
- Place of Presentation
  Il Ciocco, Italy
- Data Source
  KAKENHI-PLANNED-22110005
[Presentation] 球脊髄性筋萎縮症モデルマウスにおける異常蛋白凝集の病理学的分布はHsf-1の影響を受ける2011
- Author(s)
  近藤直英, 勝野雅央, 足立弘明, 南山誠, 土井英樹, 松本慎二郎, 宮崎雄, 飯田円, 田中章景, 祖父江元
- Organizer
  第52回日本神経学会学術大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23390230
[Presentation] 球脊髄性筋萎縮症モデルにおける抗アンドロゲン療法とHGF高発現の混合療法の効果2010
- Author(s)
  足立弘明, ら
- Organizer
  第52回日本神経学会総会
- Place of Presentation
  東京国際フォーラム(東京)
- Year and Date
  2010-05-22
- Data Source
  KAKENHI-PROJECT-21659220
[Presentation] A peony extract alleviates polyglutamine-mediated motor neuron disease2010
- Author(s)
  Adachi H, Tohnai G, Katsuno M, Minamiyama M, Doi H, Matsumoto S, Kondo N, Miyazaki Y, Tanaka F, Sobue G.
- Organizer
  Neuroscience 2010
- Place of Presentation
  San Diego, USA
- Year and Date
  2010-11-16
- Data Source
  KAKENHI-PROJECT-21229011
[Presentation] Disrupted TGF-beta signaling in spinal and bulbar muscular atrophy.2010
- Author(s)
  Katsuno M, Adachi H, Minamiyama M, Doi H, Kondo N, Matsumoto S, Miyazaki Y, Banno H, Suzuki K, Tanaka F, Sobue G.
- Organizer
  21st International Symposium on ALS/MND.
- Place of Presentation
  Orlando, USA
- Data Source
  KAKENHI-PLANNED-22110005
[Presentation] A peony extract alleviates polyglutamine-mediated motor neuron disease.2010
- Author(s)
  Adachi H, Tohnai G, Katsuno M, Minamiyama M, Doi H, Matsumoto S, Kondo N, Miyazaki Y, Tanaka F, Sobue G.
- Organizer
  Neuroscience 2010
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PLANNED-22110005
[Presentation] 球脊髄性筋萎縮症(SBMA)におけるナトリウムチャンネルの発現異常2010
- Author(s)
  勝野雅央、足立弘明、南山誠、土井英樹、近藤直英、松本慎二郎、坂野晴彦、鈴木啓介、田中章景、祖父江元
- Organizer
  Neuro2010
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PLANNED-22110005
[Presentation] A peony extract alleviates polyglutamine-mediated motor neuron disease2010
- Author(s)
  Adachi H, et al
- Organizer
  Society for Neuroscience
- Place of Presentation
  San Diego conventioncenter (San Diego)
- Year and Date
  2010-11-17
- Data Source
  KAKENHI-PROJECT-20390243
[Presentation] Disrupted TGF-beta signaling in spinal and bulbar muscular atrophy.2010
- Author(s)
  Katsuno M, Adachi H, Minamiyama M, Doi H, Kondo N, Matsumoto S, Miyazaki Y, Banno H, Suzuki K, Tanaka F, Sobue G.
- Organizer
  21st International Symposium on ALS/MND.
- Place of Presentation
  Orlando, USA
- Year and Date
  2010-12-12
- Data Source
  KAKENHI-PROJECT-21229011
[Presentation] A peony extract alleviates polyglutamine-mediated motor neuron disease2010
- Author(s)
  Adachi H, Tohnai G, Katsuno M, Minamiyama M, Doi H, Matsumoto S, Kondo N, Miyazaki Y, Tanaka F, Ohtsuka K, Sobue G.
- Organizer
  40th Annual Meeting for the Society for Neuroscience
- Place of Presentation
  San Diego
- Year and Date
  2010-11-17
- Data Source
  KAKENHI-PROJECT-20390243
[Presentation] TDP-43 depletion induces neuronal cell damage through dysregulation of Rho family GTPases2009
- Author(s)
  Iguchi Y, Katsuno M, Niwa J, Yamada S, Sone J, Waza M, Adachi H, Tanaka F, Nagata K, Arimura N, Watanabe T, Kaibuchi K, Sobue G.
- Organizer
  Neuroscience 2009
- Place of Presentation
  Chicago, USA
- Year and Date
  2009-10-17
- Data Source
  KAKENHI-PROJECT-21229011
[Presentation] Medical induction of stress response alleviates polyglutamine-mediated motor neuron disease The 4th International Congress Responses in Biology and Medicine (CSSI)2009
- Author(s)
  Tohnai G, Adachi H, Tokui K, Waza M, Katsuno M, Minamiyama M, Doi H, Tanaka F, Ohtsuka K, Sobue G.
- Organizer
  The 4th Annual Meeting of The Biomedical Society for Stress Response (BSSR)
- Place of Presentation
  Sapporo(一般演題)
- Data Source
  KAKENHI-PROJECT-20390243
[Presentation] 球脊髄性筋萎縮症モデルにおける抗アンドロゲン療法とHGF高発現の混合療法の効果2009
- Author(s)
  足立弘明, ら
- Organizer
  第50回日本神経学会総会
- Place of Presentation
  仙台
- Year and Date
  2009-05-21
- Data Source
  KAKENHI-PROJECT-21659220
[Presentation] Phase 2 trial of leuprorelin in patients with spinal and bulbar muscular atrophy2009
- Author(s)
  Banno H, Katsuno M, Suzuki K, Takeuchi Y, Kawashima M, Suga N, Takamori M, Ito M, Nakamura T, Matsuo K, Yamada S, Oki Y, Adachi H, Minamiyama M, Waza M, Atsuta N, Watanabe H, Fujimoto Y, Nakashima T, Tanaka F, Doyu M, Sobue G.
- Organizer
  61th American Academy of Neurology Annual Meeting
- Place of Presentation
  Seattle, USA
- Year and Date
  2009-04-26
- Data Source
  KAKENHI-PROJECT-21229011
[Presentation] TDP-43 depletion induces neuronal cell damage through dysregulation of Rho family GTPases2009
- Author(s)
  Iguchi Y, Katsuno M, Niwa JI, Sone J, Waza M, Adachi H, Tanaka F, Nagata KI, Arimura N, Watanabe T, Kaibuchi K, Sobue G.
- Organizer
  39th Annual Meeting for the Society for Neuroscience
- Place of Presentation
  Chicago, IL(一般演題)
- Year and Date
  2009-10-18
- Data Source
  KAKENHI-PROJECT-20390243
[Presentation] Skeletal muscle involvement in spinal and bulbar muscular atrophy2008
- Author(s)
  Katsuno M, Kawashima M, Banno H, Suzuki K, Takeuchi Y, Suga N, Adachi H, Tanaka F, Sobue G
- Organizer
  The 19th International Symposium on ALS/MND
- Place of Presentation
  Birmingham, UK
- Data Source
  KAKENHI-PROJECT-19209033
[Presentation] SBMAモデルにおけるプロテアソーム機能と17-DMAGの治療効果2008
- Author(s)
  足立弘明, ら
- Organizer
  第3回臨床ストレス応答学会
- Place of Presentation
  秋田
- Year and Date
  2008-11-14
- Data Source
  KAKENHI-PROJECT-20390243
[Presentation] An oral Hsp90 inhibitor ameliorates phenotypes of the spinal and bulbar muscular atrophy transgenic mouse model2008
- Author(s)
  Adachi H, Tokui K, Waza M, Katsuno M, Minamiyama M, Doi H, Tanaka F, Sobue G
- Organizer
  Neuroscience 2009
- Place of Presentation
  Washington DC, USA
- Data Source
  KAKENHI-PROJECT-19209033
[Presentation] An oral Hsp90 inhibitor ameliorates phenotypes of the spinal and bulbar muscular atrophy transgenic mouse model.2008
- Author(s)
  Adachi H, et al
- Organizer
  Neuroscience 2009.
- Place of Presentation
  washington DC, USA
- Data Source
  KAKENHI-PROJECT-19209033
[Presentation] An oral Hsp9O inhibitor ameliorates phenotypes of the spinal and bulbar muscular atrophy transgenic mouse model2008
- Author(s)
  Adachi H, Tokui K, Katsuno M, Minamiyama M, Doi H, Tanaka F, Sobue G.
- Organizer
  第38回The Society for Neuroscience Annual meeting
- Place of Presentation
  Washington DC(一般演題)
- Data Source
  KAKENHI-PROJECT-20390243
[Presentation] Dynactin-1ノックダウン線虫モデルの作成2008
- Author(s)
  和座雅浩、田中章景、蒋月梅、黄哲、勝野雅央、足立弘明、山本正彦、祖父江元
- Organizer
  第49回日本神経学会総会
- Place of Presentation
  横浜
- Year and Date
  2008-05-16
- Data Source
  KAKENHI-PROJECT-19390238
[Presentation] CHIP over-expression reduces the mutant AR protein and ameliorates phenotypes of the SBMA transgenic mouse model2007
- Author(s)
  Adachi, H, Waza, M, Tokui, K, Katsuno, M, Minamiyama, M. Tanaka, F, Sobue, G
- Organizer
  The 49th Annual Meeting of the Japanese Society of Neurology
- Place of Presentation
  Nagoya
- Year and Date
  2007-05-17
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18599002
[Presentation] CHIP overexpression reduces the mutant AR protein and ameliorates phenotypes of the SBMA transgenic mouse model2007
- Author(s)
  Adachi H, Waza M, Tokui K, Katsuno M, Tanaka F, Sobue G
- Organizer
  Neuroscience 2007
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-19209033
[Presentation] 球脊髄性筋萎縮症モデルにおけるシャペロン依存性ユビキチンリガーゼ高発現の効果2007
- Author(s)
  足立弘明, ら
- Organizer
  第48回日本神経学会総会
- Place of Presentation
  名古屋
- Year and Date
  2007-05-17
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18599002
[Presentation] 蛋白質分解システムの強化による球脊髄性筋萎縮症の病態の改善
- Author(s)
  足立弘明
- Organizer
  第57回日本小児神経学会
- Place of Presentation
  帝国ホテル大阪（大阪府・大阪市）
- Year and Date
  2015-05-28 – 2015-05-30
- Data Source
  KAKENHI-PROJECT-26293207
[Presentation] 神経変性疾患のトランスレーショナルリサーチ
- Author(s)
  勝野雅央, 坂野晴彦, 鈴木啓介, 橋詰淳, 足立弘明, 田中章景, 祖父江元.
- Organizer
  第109回日本内科学会総会・講演会シンポジウム「わが国のトランスレーショナルリサーチとEBM」
- Place of Presentation
  みやこめっせ（京都）
- Invited
- Data Source
  KAKENHI-PROJECT-21229011
[Presentation] オートファジーによる変異アンドロゲン受容体の分解とその治療への応用
- Author(s)
  足立弘明
- Organizer
  第55回日本神経学会学術大会
- Place of Presentation
  福岡国際会議場(福岡県・福岡市）
- Year and Date
  2014-05-21 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-26293207
[Presentation] 神経変性疾患におけるオートファジーの利用による病因蛋白質の分解
- Author(s)
  足立弘明
- Organizer
  第38回日本神経科学大会
- Place of Presentation
  神戸国際会議場（兵庫県・神戸市）
- Year and Date
  2015-07-28 – 2015-07-31
- Data Source
  KAKENHI-PROJECT-26293207
[Presentation] Molecular pathogenesis and therapy of polyglutamine-induced motor neuron degeneration.
- Author(s)
  Katsuno M, Adachi H, Minamiyama M, Doi H, Kondo N, Miyazaki Y, Iida M, Tanaka F, Sobue G.
- Organizer
  35th Annual Meeting of the Japan Neuroscience Society.
- Place of Presentation
  名古屋国際会議場（名古屋）
- Invited
- Data Source
  KAKENHI-PROJECT-23390230
[Presentation] The enhancement of protein degradation via autophagy in neurodegeneration
- Author(s)
  足立弘明
- Organizer
  第56回日本神経学会学術大会
- Place of Presentation
  朱鷺メッセ (新潟県・新潟市)
- Year and Date
  2015-05-20 – 2015-05-23
- Data Source
  KAKENHI-PROJECT-26293207
[Presentation] SBMA motor dysfunction may be due to failed neuromuscular transmission.
- Author(s)
  Xu, Atchison W, Adachi H, Katsuno M, Sobue G, Breedlove S, Jordan CL.
- Organizer
  Neuroscience 2014
- Place of Presentation
  Washington DC, USA
- Year and Date
  2014-11-15 – 2014-11-19
- Data Source
  KAKENHI-PLANNED-22110005
[Presentation] 変異蛋白質の分解と封入体形成の治療的意義
- Author(s)
  足立弘明
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  国立京都国際会館（京都府・京都市）
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-26293207
[Presentation] Androgen-dependent deficits in muscle-derived BDNF correlate with motor dysfunction in two mouse models of spinal bulbar muscular atrophy.
- Author(s)
  Halievski K, Xu Y, Henley CL, Katsuno M, Adachi H, Sobue G, Breedlove S, Jordan CL.
- Organizer
  Neuroscience 2014
- Place of Presentation
  Washington DC, USA
- Year and Date
  2014-11-15 – 2014-11-19
- Data Source
  KAKENHI-PLANNED-22110005

1. SOBUE Gen (20148315)

# of Collaborated Projects: 10 results

# of Collaborated Products: 153 results
2. KATSUNO Masahisa (50402566)

# of Collaborated Projects: 8 results

# of Collaborated Products: 148 results
3. TANAKA Fumiaki (30378012)

# of Collaborated Projects: 7 results

# of Collaborated Products: 97 results
4. DOYU Manabu (90293703)

# of Collaborated Projects: 4 results

# of Collaborated Products: 10 results
5. IIJIMA Masahiro (40437041)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. KOIKE Haruki (80378174)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 黄哲 (30745112)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
8. 豊田知子 (30596432)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
9. OKADA Youhei (30383714)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. OKANO Hideyuki (60160694)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. TANAKA Keiji (10108871)

# of Collaborated Projects: 1 results

# of Collaborated Products: 40 results
12. FUNAKOSHI Hiroshi (40273685)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 鈴木啓介 (70635408)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
14. 岡田和将 (30341499)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
15. 岩中行己男 (60590461)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
16. 橋本智代 (70425685)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
17. MIYAZAKI Yu

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
18. YAJIMA Ichiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. KATO masashi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. KINO Yoshihiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. INOMATA Megumi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. WATANABE Hirohisa

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. TANABE hiroki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 貫名信行

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 三輪高喜

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 大神信孝

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. 飯田真智子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. 宮武聡子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. 近藤直英

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. 濱谷沙世

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Adachi Hiroaki 足立 弘明

ADACHI Hiroaki 足立 弘明

Research Projects

Research Products

Co-Researchers

Reducing toxicity of disease-causative molecules with the aim of developing therapies for neurodegenerative diseasesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Reducing toxicity of disease-causative molecules with the aim of developing therapies for neurodegenarative diseasesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Discovery of novel autophagy regulators for treatment of neurodegenerative diseasesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Selective protein degradation with the aim of developing therapies for neurodegenarative diseasesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Therapeutic strategy of neurodegenerative disease using microRNA

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Elucidation of activity-dependent synapse pathology and development of therapy for spinal and bulbar muscular atrophy

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Development of therapy targeting dysregulation of cell cycle and JNK pathway in polyglutamine diseases

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Novel therapeutic approaches using the delivery of specific miRNAs for polyglutamine diseasesPrincipal Investigator

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Elucidation of molecular pathogenesis in motor neurocircuit degeneration and development of therapy for motor neuron diseases

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Review Section

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Development of Molecular Targeted Disease Modifying Therapy for Polyglutamine Diseases

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ポリグルタミン病の病態抑止治療と神経賦活治療の併用療法Principal Investigator

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Therapeutic strategy for polyglutamine-mediated motor neuron disease via molecular chaperone-ubiquitin proteasome systemPrincipal Investigator

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Pathogenesis-based therapy development for polyglutamine diseases

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Adachi Hiroaki 足立弘明

ADACHI Hiroaki 足立弘明

[Book] 今日の治療指針ミオクローヌス2021

[Book] 産業医が診る働き方改革増補改訂版2020