Ogawa Tadayuki 小川覚之

… Alternative Names

小川覚之オガワタダユキ

OGAWA Tadayuki 小川覚之

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Researcher Number	40436572
Other IDs	https://orcid.org/0000-0002-4627-0693
Affiliation (Current)	2024: 獨協医科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2024: 獨協医科大学, 医学部, 講師 2021 – 2022: 獨協医科大学, 医学部, 講師 2020: 東京大学, 大学院医学系研究科(医学部), 助教 2015: 東京大学, 大学院医学系研究科, 特任助教 2010: 東京大学, 大学院・医学系研究科, 特任助教
Review Section/Research Field	Principal Investigator Basic Section 34020:Analytical chemistry-related / Complex systems / Basic Section 48010:Anatomy-related Except Principal Investigator Biological Sciences / Basic Section 49030:Experimental pathology-related / Basic Section 48010:Anatomy-related / Basic Section 59040:Nutrition science and health science-related
Keywords	Principal Investigator 死後脳 / 認知症 / 疾患プロテオミクス / MSイメージング / メタロミクス / 質量分析 / プロテオミクス / 神経変性疾患 / 分子構造病態 / 神経変性 … More / オミクス / オミクス解析 / パーキンソン病 / レビー小体 / アルツハイマー型認知症 / タンパク質構造動態 / オミクス解析 / 金属タンパク質 / 疾患シグナル / タンパク質病態 / ALS / 分子イメージング / 溶液中分子動態 / 筋萎縮性側索硬化症(ALS) … More Except Principal Investigator 線維芽細胞 / 細胞内物質輸送 / 微小管 / 細胞内輸送 / キネシン / 分子モーター / 幹細胞 / 脂質 / 血管 / 脳梗塞 / ミクログリア / T細胞産生 / 免疫寛容 / トランスクリプトーム / 樹状細胞 / 胸腺 / 支持細胞 / 胎児 / 腸炎 / 炎症 / 脂肪酸 / 線毛 / 不安神経症 / 癲癇 / 高脂血症 / クライオ電子顕微鏡 / KIFs / MAP1A / KIF2A / KIF3 / KIF16B / リン酸化 / 統合生物学 / キネシンモーター分子群 / 構造生物学 / 分子遺伝学 / 分子細胞生物学 / モーター蛋白 Less

認知症死後脳のハイブリッドオミクス解析による認知症発症起源と疾患構造動態の解明Principal Investigator
- Principal Investigator
  
  小川覚之
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 34020:Analytical chemistry-related
- Research Institution
  Dokkyo Medical University
脳梗塞巣はどのように排出されるのか？－ミクログリアによる脂質代謝の可視化で迫る－
- Principal Investigator
  
  澤野俊憲
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  Ritsumeikan University
免疫寛容プラットフォームとしてのラット胸腺髄質の上皮細胞欠損領域の解析
- Principal Investigator
  
  沢登祥史
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48010:Anatomy-related
- Research Institution
  Dokkyo Medical University
筋萎縮性側索硬化症ALS死後脳における多量体形成分子群の神経変性病態構造の解明Principal Investigator
- Principal Investigator
  
  小川覚之
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48010:Anatomy-related
- Research Institution
  Dokkyo Medical University
  The University of Tokyo
認知症死後脳における金属タンパク質の疾患特異的分子構造病態の解明Principal Investigator
- Principal Investigator
  
  小川覚之
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Dokkyo Medical University
  The University of Tokyo
胎児期からの脂肪酸摂取バランスが炎症性腸疾患の寛解と再燃に与える影響
- Principal Investigator
  
  徳田信子
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Dokkyo Medical University
Integrative biological research on function and regulation of Kinesin superfamily molecular motors
- Principal Investigator
  
  HIROKAWA Nobutaka
- Project Period (FY)
  2011 – 2015
- Research Category
  
  Grant-in-Aid for Specially Promoted Research
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
The Mechanism of Intracellular Transport and Kinesin Motors, KIFs : Structure, Function, Dynamics and Regulation
- Principal Investigator
  
  HIROKAWA Nobutaka
- Project Period (FY)
  2006 – 2010
- Research Category
  
  Grant-in-Aid for Specially Promoted Research
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo

All 2023 2022 2021 2020 2016 2015

All Journal Article Presentation

[Journal Article] A neuropathy‐associated kinesin KIF1A mutation hyper‐stabilizes the motor‐neck interaction during the ATPase cycle2022
- Author(s)
  Morikawa Manatsu、Jerath Nivedita U、Ogawa Tadayuki、Morikawa Momo、Tanaka Yosuke、Shy Michael E、Zuchner Stephan、Hirokawa Nobutaka
- Journal Title
  
  The EMBO Journal
  
  Volume: 41 Issue: 5
- DOI
  10.15252/embj.2021108899
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K16483, KAKENHI-PUBLICLY-20H05499, KAKENHI-PROJECT-20K07222
[Journal Article] Betaine ameliorates schizophrenic traits by functionally compensating for KIF3-based CRMP2 transport2021
- Author(s)
  Yoshihara Shogo、Jiang Xuguang、Morikawa Momo、Ogawa Tadayuki、Ichinose Sotaro、Yabe Hirooki、Kakita Akiyoshi、Toyoshima Manabu、Kunii Yasuto、Yoshikawa Takeo、Tanaka Yosuke、Hirokawa Nobutaka
- Journal Title
  
  Cell Reports
  
  Volume: 35 Issue: 2 Pages: 108971-108971
- DOI
  10.1016/j.celrep.2021.108971
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-20H05499, KAKENHI-PROJECT-20J00876, KAKENHI-PROJECT-20K07222, KAKENHI-PROJECT-16H06277
[Journal Article] 統合失調症に関連する分子の「質」：遺伝子・環境因子からタンパク質まで．2020
- Author(s)
  豊島学，蒋緒光，小川覚之，廣川信隆，吉川武男．
- Journal Title
  
  分析化学
  
  Volume: 69巻10-11号 Issue: 10.11 Pages: 531-537
- DOI
  10.2116/bunsekikagaku.69.531
- NAID
  130007927226
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08023, KAKENHI-PROJECT-20K07222, KAKENHI-PUBLICLY-20H05499
[Journal Article] X-ray and cryo-EM structures reveal mutual conformational changes of Kinesin and GTP-state microtubules upon binding.2015
- Author(s)
  Morikawa M, Yajima H, Nitta R, Inoue S, Ogura T, Sato C, Hirokawa N
- Journal Title
  
  The EMBO Journal
  
  Volume: 34 Issue: 9 Pages: 1270-86
- DOI
  10.15252/embj.201490588
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-13J05975, KAKENHI-PROJECT-23000013, KAKENHI-PROJECT-15K08168, KAKENHI-PROJECT-15K14499, KAKENHI-PROJECT-15H04365, KAKENHI-PROJECT-25650057
[Journal Article] Microtubule destabilizer KIF2A undergoes distinct site-specific phosphorylation cascades that differentially affect neuronal morphogenesis.2015
- Author(s)
  Ogawa, T. and N. Hirokawa
- Journal Title
  
  Cell Reports
  
  Volume: 12 Issue: 11 Pages: 1-15
- DOI
  10.1016/j.celrep.2015.08.018
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23000013
[Presentation] Hybrid Imaging Analyses of Biomolecules: From Biological Tissues to Molecules and Metals2023
- Author(s)
  Tadayuki Ogawa
- Organizer
  International symposium on mass spectrometry imaging 2023 KYOTO
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07222
[Presentation] 生体組織の統合オミクス解析：組織から分子、原子へ2023
- Author(s)
  小川覚之
- Organizer
  第128回日本解剖学会全国学術集会
- Data Source
  KAKENHI-PROJECT-20K07222
[Presentation] 大気圧低温プラズマによる生体分子イオン化装置の開発2023
- Author(s)
  小川覚之、沖野晃俊、平田岳史
- Organizer
  第1回生体医歯工学共同研究拠点成果報告会
- Invited
- Data Source
  KAKENHI-PROJECT-20K07222
[Presentation] 質量分析イメージングによる心臓組織・心内膜・心外膜の分子局在解析2023
- Author(s)
  西山侑輝、野老翔雲、大島典子、徳田信子、豊田茂、小川覚之
- Organizer
  第128回日本解剖学会全国学術集会
- Data Source
  KAKENHI-PROJECT-20K07222
[Presentation] Integrated Omics: ヒト疾患脳から分子病態へ2022
- Author(s)
  小川覚之
- Organizer
  第１回　生体分子ナノ解析・イメージング研究会
- Data Source
  KAKENHI-PUBLICLY-20H05499
[Presentation] 高輝度放射光を利用した分子モータータンパク質の神経変性疾患型変異の構造動態解析2022
- Author(s)
  小川覚之
- Organizer
  大阪大学蛋白質研究所セミナー/Spring-8先端利用技術ワークショップ
- Invited
- Data Source
  KAKENHI-PROJECT-20K07222
[Presentation] 分離と検出を一枚のプレートで実現する酸化亜鉛ナノワイヤの魅力2022
- Author(s)
  梅村知也、森岡和大、東海林敦、嶋田泰佑、安井隆雄、小川覚之、沖野晃俊
- Organizer
  第53回中部化学関係学協会支部連合秋季大会
- Data Source
  KAKENHI-PROJECT-20K07222
[Presentation] 生体分子のハイブリッドイメージング:生体組織から分子、金属元素へ2022
- Author(s)
  小川覚之
- Organizer
  プラズマ分光分析研究会第 116 回講演会
- Invited
- Data Source
  KAKENHI-PROJECT-20K07222
[Presentation] ヒト疾患のハイブリッド分析：脳疾患イメージングから結合組織疾患まで2022
- Author(s)
  小川覚之
- Organizer
  第２回生体分子ナノ解析・イメージング研究会
- Invited
- Data Source
  KAKENHI-PROJECT-20K07222
[Presentation] Integrated Omics: ヒト疾患脳から分子病態へ2022
- Author(s)
  小川覚之
- Organizer
  第１回　生体分子ナノ解析・イメージング研究会
- Data Source
  KAKENHI-PROJECT-20K07222
[Presentation] マイクロPIXEによる神経組織中生命金属分布解析2022
- Author(s)
  小川覚之、及川将一、上原章寛、武田志乃
- Organizer
  放射線医学研究所成果報告会
- Invited
- Data Source
  KAKENHI-PROJECT-20K07222
[Presentation] 生体分子の統合的オミクス解析：生体組織から分子、原子へ2022
- Author(s)
  小川覚之、梅村知也、武田志乃、平田岳史
- Organizer
  第70回質量分析総合討論会(2022)
- Data Source
  KAKENHI-PROJECT-20K07222
[Presentation] Hybrid Imaging Analyses of Biomolecules: From Biological Tissues to Molecules and Metals2022
- Author(s)
  Tadayuki Ogawa, Eisei Tanaka, Tomonari Umemura, Shino Takeda-Homma, Takafumi Hirata
- Organizer
  The 8th International Symposium on Metallomics (ISM-8)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07222
[Presentation] 神経変性疾患死後脳の生命金属分析科学2021
- Author(s)
  小川覚之
- Organizer
  新学術領域研究「生命金属科学」夏合宿
- Data Source
  KAKENHI-PROJECT-20K07222
[Presentation] 疾患脳における金属タンパク質の疾患特異的分子病態解明へ2021
- Author(s)
  小川覚之
- Organizer
  新学術領域研究「生命金属科学」領域会議　第四回地方巡業
- Data Source
  KAKENHI-PUBLICLY-20H05499
[Presentation] 量子ビームで迫る微小管関連タンパク質構造動態：疾患から分子構造病態まで2021
- Author(s)
  小川覚之
- Organizer
  量子ビームサイエンスフェスタ（主催：KEK物質構造科学研究所・J-PARCセンター・総合科学研究機構）(招待講演)
- Invited
- Data Source
  KAKENHI-PROJECT-20K07222
[Presentation] 疾患脳から迫る疾患特異的金属蛋白質の分子構造病態解析2021
- Author(s)
  小川覚之
- Organizer
  蛋白質科学会
- Invited
- Data Source
  KAKENHI-PROJECT-20K07222
[Presentation] 疾患脳から迫る疾患特異的金属蛋白質の分子構造病態解析2021
- Author(s)
  小川覚之
- Organizer
  令和3年度　蛋白質科学会
- Invited
- Data Source
  KAKENHI-PUBLICLY-20H05499
[Presentation] 神経変性疾患死後脳の生命金属分析科学2021
- Author(s)
  小川覚之
- Organizer
  新学術領域研究「生命金属科学」夏合宿
- Data Source
  KAKENHI-PUBLICLY-20H05499
[Presentation] 量子ビームで迫る微小管関連タンパク質構造動態：疾患から分子構造病態まで2021
- Author(s)
  小川覚之
- Organizer
  2020年度量子ビームサイエンスフェスタ
- Invited
- Data Source
  KAKENHI-PUBLICLY-20H05499
[Presentation] 疾患脳から迫る疾患特異的金属蛋白質の分子構造病態解析2021
- Author(s)
  小川覚之
- Organizer
  蛋白質科学会ワークショップ「生命金属科学の最前線」
- Invited
- Data Source
  KAKENHI-PUBLICLY-20H05499
[Presentation] 量子ビームで迫る微小管関連タンパク質構造動態：疾患から分子構造病態まで2021
- Author(s)
  小川覚之
- Organizer
  2020年度量子ビームサイエンスフェスタ
- Invited
- Data Source
  KAKENHI-PROJECT-20K07222
[Presentation] 疾患脳における金属タンパク質の疾患特異的分子病態解明へ2021
- Author(s)
  小川覚之
- Organizer
  新学術領域研究「生命金属科学」領域会議　第四回地方巡業（東京）
- Data Source
  KAKENHI-PROJECT-20K07222
[Presentation] 量子ビームで迫る微小管関連タンパク質構造動態：疾患から分子構造病態まで2021
- Author(s)
  小川覚之
- Organizer
  2020年度量子ビームサイエンスフェスタ（主催：KEK物質構造科学研究所・J-PARCセンター・総合科学研究機構）
- Invited
- Data Source
  KAKENHI-PUBLICLY-20H05499
[Presentation] 疾患脳から迫る疾患特異的金属蛋白質の分子構造病態解析2021
- Author(s)
  小川覚之
- Organizer
  令和3年度蛋白質科学会
- Invited
- Data Source
  KAKENHI-PROJECT-20K07222
[Presentation] 認知症脳における金属タンパク質の疾患特異的分子病態解明へ向けて2020
- Author(s)
  小川覚之
- Organizer
  新学術領域「生命金属科学」第４回領域会議
- Data Source
  KAKENHI-PUBLICLY-20H05499
[Presentation] 認知症脳における金属タンパク質の疾患特異的分子病態解明へ向けて2020
- Author(s)
  小川覚之
- Organizer
  新学術領域「生命金属科学」第４回領域会議
- Data Source
  KAKENHI-PROJECT-20K07222
[Presentation] 異なる特異的リン酸化カスケードによる微小管脱重合蛋白質KIF2Aの制御機構2016
- Author(s)
  小川覚之、廣川信隆
- Organizer
  第121回日本解剖学会総会・学術大会
- Place of Presentation
  ビッグパレットふくしま(福島県郡山市)
- Year and Date
  2016-03-28
- Data Source
  KAKENHI-PROJECT-23000013
[Presentation] 異なる特異的リン酸化カスケードによる微小管脱重合蛋白質KIF2Aの制御機構2015
- Author(s)
  小川覚之、廣川信隆
- Organizer
  第38回日本分子生物学会年会/第88回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートアイランド(兵庫県神戸市)
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-23000013
[Presentation] Microtubule Destabilizer KIF2A Undergoes Distinct Site-specific Phosphorylation Cascades for Neuronal Morphogenesis2015
- Author(s)
  Ogawa, T. and Hirokawa, N.
- Organizer
  The Annual Meeting of American Society for Cell Biology
- Place of Presentation
  The San Diego Convention Center, San Diego, CA. USA
- Year and Date
  2015-12-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23000013
[Presentation] Mechanism of Activity-Dependent Cargo Loading via the Phosphorylation of KIF3A by PKA and CaMKIIa.2015
- Author(s)
  Ichinose, S., Ogawa, T., and Hirokawa, N.
- Organizer
  The Annual Meeting of American Society for Cell Biology
- Place of Presentation
  The San Diego Convention Center, San Diego, CA. USA
- Year and Date
  2015-12-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23000013

1. KANAI Yoshimitsu (80214427)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. TAKEI Yosuke (20272487)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. OKADA Yasushi (50272430)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. HIROKAWA Nobutaka (20010085)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. NAKATA Takao (50218004)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. NODA Yasuko (50262019)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. TANAKA Yosuke (90302661)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. NITTA Ryo (40345038)

# of Collaborated Projects: 2 results

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9. HOMMA Noriko (50345039)

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10. MIKI Harukata (10361461)

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11. YAJIMA Hiroaki (30376412)

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12. 齊藤祐子 (60344066)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. 川島祐介 (30588124)

# of Collaborated Projects: 2 results

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14. 徳田信子 (70227578)

# of Collaborated Projects: 1 results

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15. 大和田祐二 (20292211)

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16. 入澤篤志 (60295409)

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17. 山本由似 (80635087)

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18. 沢登祥史 (40525052)

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19. 平田岳史 (10251612)

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20. 梅村知也 (10312901)

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21. 鬼塚正義 (80571174)

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22. 澤野俊憲 (60805597)

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23. 土江伸誉 (00434879)

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24. TOYOSHIMA Manabu

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25. 広川信隆

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results
26. 森田真夏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ogawa Tadayuki 小川 覚之

小川 覚之 オガワ タダユキ

OGAWA Tadayuki 小川 覚之

Research Projects

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Co-Researchers

認知症死後脳のハイブリッドオミクス解析による認知症発症起源と疾患構造動態の解明Principal Investigator

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脳梗塞巣はどのように排出されるのか？－ミクログリアによる脂質代謝の可視化で迫る－

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免疫寛容プラットフォームとしてのラット胸腺髄質の上皮細胞欠損領域の解析

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筋萎縮性側索硬化症ALS死後脳における多量体形成分子群の神経変性病態構造の解明Principal Investigator

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認知症死後脳における金属タンパク質の疾患特異的分子構造病態の解明Principal Investigator

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胎児期からの脂肪酸摂取バランスが炎症性腸疾患の寛解と再燃に与える影響

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Integrative biological research on function and regulation of Kinesin superfamily molecular motors

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The Mechanism of Intracellular Transport and Kinesin Motors, KIFs : Structure, Function, Dynamics and Regulation

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[Journal Article] A neuropathy‐associated kinesin KIF1A mutation hyper‐stabilizes the motor‐neck interaction during the ATPase cycle2022

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[Journal Article] Betaine ameliorates schizophrenic traits by functionally compensating for KIF3-based CRMP2 transport2021

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[Journal Article] 統合失調症に関連する分子の「質」：遺伝子・環境因子からタンパク質まで．2020

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NAID

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[Journal Article] X-ray and cryo-EM structures reveal mutual conformational changes of Kinesin and GTP-state microtubules upon binding.2015

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[Journal Article] Microtubule destabilizer KIF2A undergoes distinct site-specific phosphorylation cascades that differentially affect neuronal morphogenesis.2015

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Ogawa Tadayuki 小川覚之

小川覚之オガワタダユキ

OGAWA Tadayuki 小川覚之