Hoshi Masato 星雅人

… Alternative Names

HOSHI Masato 星雅人

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Researcher Number	40633996
Other IDs
Affiliation (Current)	2025: 藤田医科大学, 医療科学研究科, 准教授
Affiliation (based on the past Project Information) *help	2025: 藤田医科大学, 医療科学研究科, 准教授 2021 – 2022: 藤田医科大学, 保健学研究科, 准教授 2018 – 2021: 藤田医科大学, 保健学研究科, 講師 2016 – 2017: 藤田保健衛生大学, 医療科学部, 講師 2012 – 2015: 鈴鹿医療科学大学, 保健衛生学部, 助教
Review Section/Research Field	Principal Investigator Laboratory medicine / Basic Section 59040:Nutrition science and health science-related / Basic Section 49030:Experimental pathology-related Except Principal Investigator Basic Section 53030:Respiratory medicine-related / Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
Keywords	Principal Investigator トリプトファン代謝 / IDO / 3-hydroxykynurenine / KMO / IDO2 / IDO1 / Ｂ１６Ｆ１０ / ＩＤＯ２ / ＩＤＯ１ / B16F10細胞 … More / トリプトファン代謝産物 / α-ガラクトシルセラミド / 炎症性サイトカイン / 敗血症 / LPS / CLP / Sepsis / ATF4 / Interleukin-6 / Endotoxic shock / 3-hydroxykinurenine / ＫＭＯ / Ro61-8048 / B16F１０細胞 / がん微小環境 / キサンツレン酸 / キヌレニン / KAT / 1-metyl-L-tryptophan / 1-metyl-D-tryptophan / トリプタファン代謝 / Ｂ１６細胞 / ＩＤＯ / １－MT / α－ガラクトシルセラミド / B16F10 / 細胞免疫療法 / 抗腫瘍効果 / インドールアミン酸素添加酵素2 / インドールアミン酸素添加酵素1 / α- ガラクトシルセラミド / 腫瘍 / NKT細胞免疫療法 / インドールアミン酸素添加酵素 … More Except Principal Investigator 肺がん / トリプトファン / 肺癌 / 出生時体重 / 周産期栄養状態 / 周産期うつ / 産後うつ病 / トリプトファン代謝 / アミノ酸代謝 / 周産期うつ病 Less

希少糖を用いた制御性T細胞の新規分化誘導機構の解明と機能的応用Principal Investigator
- Principal Investigator
  
  星雅人
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Fujita Health University
Targeting Tryptophan Metabolism for Immune Regulation of Sepsis and Novel Therapeutic StrategiesPrincipal Investigator
- Principal Investigator
  
  Hoshi Masato
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  Fujita Health University
analysis of lung cancer immunotherapy targeting tryptophan metabolism
- Principal Investigator
  
  Kondo Masashi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Fujita Health University
Relationship between changes in amino acid metabolism during pregnancy and postpartum depression.
- Principal Investigator
  
  Saito Kuniaki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
- Research Institution
  Fujita Health University
Establishment and pathological analysis of novel immunotherapy by control of tryptophan-metabolizing enzymes in metastatic tumorsPrincipal Investigator
- Principal Investigator
  
  Hoshi Masato
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Laboratory medicine
- Research Institution
  Fujita Health University
The effects of NKT cell-mediated immunotherapy by IDO inhibitor in mouse lung metastasis modelPrincipal Investigator
- Principal Investigator
  
  Hoshi Masato
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Laboratory medicine
- Research Institution
  Fujita Health University
  Suzuka University of Medical Science
The investigation of immune regulation by IDO in NKT cell-mediated immunotherapyPrincipal Investigator
- Principal Investigator
  
  HOSHI Masato
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Laboratory medicine
- Research Institution
  Suzuka University of Medical Science

All 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012

All Journal Article Presentation Patent

[Journal Article] D-allose enhances the efficacy of hydroxychloroquine against Lewis lung carcinoma cell growth by inducing autophagy2022
- Author(s)
  Kyoka Yamazaki、Masato Hoshi、Hiroyuki Tezuka、Nanaka Morita、Masaya Hirayama、Fumiaki Sato、Sayaka Yoshida、Kuniaki Saito
- Journal Title
  
  Oncology Reports
  
  Volume: 47 Issue: 6 Pages: 117-117
- DOI
  10.3892/or.2022.8328
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07614, KAKENHI-PROJECT-20K07432
[Journal Article] Absence of indoleamine 2,3?dioxygenase 2 promotes liver regeneration after partial hepatectomy in mice2022
- Author(s)
  Ando Tatsuya、Hoshi Masato、Tezuka Hiroyuki、Ito Hiroyasu、Nakamoto Kentaro、Yamamoto Yasuko、Saito Kuniaki
- Journal Title
  
  Molecular Medicine Reports
  
  Volume: 27 Issue: 2 Pages: 24-24
- DOI
  10.3892/mmr.2022.12911
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07432
[Journal Article] 3-Hydroxykynurenine Regulates Lipopolysaccharide-Stimulated IL-6 Production and Protects against Endotoxic Shock in Mice2021
- Author(s)
  Hoshi Masato、Kubo Hisako、Ando Tatsuya、Tashita Chieko、Nakamoto Kentaro、Yamamoto Yasuko、Tezuka Hiroyuki、Saito Kuniaki
- Journal Title
  
  ImmunoHorizons
  
  Volume: 5 Issue: 6 Pages: 523-534
- DOI
  10.4049/immunohorizons.2100028
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07614, KAKENHI-PROJECT-20K07432
[Journal Article] Viability of diffuse large B-cell lymphoma cells is regulated by kynurenine 3-monooxygenase activity2021
- Author(s)
  Morita Nanaka、Hoshi Masato、Hara Takeshi、Ninomiya Soranobu、Enoki Taisuke、Yoneda Misao、Tsurumi Hisashi、Saito Kuniaki
- Journal Title
  
  Oncology Letters
  
  Volume: 22 Issue: 5 Pages: 110-110
- DOI
  10.3892/ol.2021.13051
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08667, KAKENHI-PROJECT-20K07432
[Journal Article] Evaluation of red blood cell parameters provided by the UF-5000 urine auto-analyzer in patients with glomerulonephritis282021
- Author(s)
  Genki Mizuno
- Journal Title
  
  Clin Chem Lab Med
  
  Volume: 28 Issue: 9 Pages: 1547-1553
- DOI
  10.1515/cclm-2021-0287
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K02505, KAKENHI-PROJECT-20K07432
[Journal Article] Kynurenine 3-monooxygenase deficiency induces depression-like behavior via enhanced antagonism of α7 nicotinic acetylcholine receptors by kynurenic acid2021
- Author(s)
  Mori Yuko、Mouri Akihiro、Kunisawa Kazuo、Hirakawa Mami、Kubota Hisayoshi、Kosuge Aika、Niijima Moe、Hasegawa Masaya、Kurahashi Hitomi、Murakami Reiko、Hoshi Masato、Nakano Takashi、Fujigaki Suwako、Fujigaki Hidetsugu、Yamamoto Yasuko、Nabeshima Toshitaka、Saito Kuniaki
- Journal Title
  
  Behavioural Brain Research
  
  Volume: 405 Pages: 113191-113191
- DOI
  10.1016/j.bbr.2021.113191
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07490, KAKENHI-PROJECT-18K19761, KAKENHI-PROJECT-17H04252, KAKENHI-PROJECT-20K07432, KAKENHI-PROJECT-20K07931, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-20K16679
[Journal Article] Kynurenine plays an immunosuppressive role in 2,4,6-trinitrobenzene sulfate-induced colitis in mice.2020
- Author(s)
  Tashita C, Hoshi M, Hirata A, Nakamoto K, Ando T, Hattori T, Yamamoto Y, Tezuka H, Tomita H, Hara A, Saito K.
- Journal Title
  
  World J Gastroenterol.
  
  Volume: 26 Issue: 9 Pages: 918-932
- DOI
  10.3748/wjg.v26.i9.918
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K15785, KAKENHI-PROJECT-19K07614, KAKENHI-PROJECT-19K08667, KAKENHI-PROJECT-18K19761, KAKENHI-PROJECT-19K23873
[Journal Article] Kynurenine produced by indoleamine 2,3-dioxygenase 2 exacerbates acute liver injury by carbon tetrachloride in mice.2020
- Author(s)
  Hoshi M, Osawa Y, Nakamoto K, Morita N, Yamamoto Y, Ando T, Tashita C, Nabeshima T, Saito K.
- Journal Title
  
  Toxicology
  
  Volume: 438 Pages: 152458-152458
- DOI
  10.1016/j.tox.2020.152458
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K15785, KAKENHI-PROJECT-19K07490, KAKENHI-PROJECT-20K07432, KAKENHI-PROJECT-18K19761, KAKENHI-PROJECT-19K23873, KAKENHI-PROJECT-17H04252
[Journal Article] Indoleamine 2,3‐dioxygenase 2 depletion suppresses tumor growth in a mouse model of Lewis lung carcinoma2019
- Author(s)
  Yamasuge Wakana、Yamamoto Yasuko、Fujigaki Hidetsugu、Hoshi Masato、Nakamoto Kentaro、Kunisawa Kazuo、Mouri Akihiro、Nabeshima Toshitaka、Saito Kuniaki
- Journal Title
  
  Cancer Science
  
  Volume: 110 Issue: 10 Pages: 3061-3067
- DOI
  10.1111/cas.14179
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07490, KAKENHI-PROJECT-18K19761, KAKENHI-PROJECT-17H04252, KAKENHI-PROJECT-17K01969, KAKENHI-PROJECT-17K15785, KAKENHI-PROJECT-18K15377
[Journal Article] Time-course analysis of cardiac and serum galectin-3 in viral myocarditis after an encephalomyocarditis virus inoculation2019
- Author(s)
  Noguchi Kei、Tomita Hiroyuki、Kanayama Tomohiro、Niwa Ayumi、Hatano Yuichiro、Hoshi Masato、Sugie Shigeyuki、Okada Hideshi、Niwa Masayuki、Hara Akira
- Journal Title
  
  PLOS ONE
  
  Volume: 14 Issue: 1 Pages: e0210971-e0210971
- DOI
  10.1371/journal.pone.0210971
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K15785, KAKENHI-PROJECT-18K15207, KAKENHI-PROJECT-16H05497
[Journal Article] Lipopolysaccharide shock reveals the immune function of indoleamine 2,3-dioxygenase 2 through the regulation of IL-6/stat3 signalling2018
- Author(s)
  Yamamoto Yasuko、Yamasuge Wakana、Imai Shinjiro、Kunisawa Kazuo、Hoshi Masato、Fujigaki Hidetsugu、Mouri Akihiro、Nabeshima Toshitaka、Saito Kuniaki
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 15917-15917
- DOI
  10.1038/s41598-018-34166-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K01969, KAKENHI-PROJECT-18K19761, KAKENHI-PROJECT-17K15785, KAKENHI-PROJECT-17H04252, KAKENHI-PROJECT-17H07222, KAKENHI-PROJECT-16K10195, KAKENHI-PROJECT-18K15377
[Journal Article] Absence of kynurenine 3-monooxygenase reduces mortality of acute viral myocarditis in mice2017
- Author(s)
  Kubo H, Hoshi M, Mouri A, Tashita C, Yamamoto Y, Nabeshima T, Saito K.
- Journal Title
  
  IMMUNOLOGY LETTERS
  
  Volume: 181 Pages: 94-100
- DOI
  10.1016/j.imlet.2016.11.012
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H03086, KAKENHI-PROJECT-26460675, KAKENHI-PROJECT-26860376, KAKENHI-PROJECT-16K10195
[Journal Article] Sake lees extract improves hepatic lipid accumulation in high fat diet-fed mice.2017
- Author(s)
  Kubo H, Hoshi M, Matsumoto T, Irie M, Oura S, Tsutsumi H, Hata Y, Yamamoto Y, Saito K
- Journal Title
  
  Lipids Health Dis.
  
  Volume: 16(1) Issue: 1 Pages: 106-106
- DOI
  10.1186/s12944-017-0501-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H07222, KAKENHI-PROJECT-17K15785, KAKENHI-PROJECT-15H03086
[Journal Article] Early microlesion of viral encephalitis confirmed by galectin-3 expression after a virus inoculation.2015
- Author(s)
  Kobayashi K, Niwa M, Hoshi M, Saito K, Hisamatsu K, Hatano Y, Tomita H, Miyazaki T, Hara A.
- Journal Title
  
  Neuroscience letters.
  
  Volume: 592 Pages: 107-112
- DOI
  10.1016/j.neulet.2015.02.061
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25460496, KAKENHI-PROJECT-26860376
[Journal Article] Inhibition of indoleamine 2,3-dioxygenase 1 expression alters immune response in colon tumor microenvironment in mice.2015
- Author(s)
  Takamatsu M, Hirata A, Ohtaki H, Hoshi M, Ando T, Ito H, Hatano Y, Tomita H, Kuno T, Saito K, Seishima M, Hara A.
- Journal Title
  
  Cancer Sci.
  
  Volume: 106(8) Issue: 8 Pages: 1008-15
- DOI
  10.1111/cas.12705
- NAID
  120005767026
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26860376
[Journal Article] Indoleamine 2,3-dioxygenase 1 is upregulated in activated microglia in mice cerebellum during acute viral encephalitis2014
- Author(s)
  Taguchi A, Niwa M, Hoshi M, Saito K, Masutani T, Hisamatsu K, Kobayashi K, Hatano Y, Tomita H, Hara A
- Journal Title
  
  Neurosci Lett
  
  Volume: 3564 Pages: 120-5
- DOI
  10.1016/j.neulet.2014.01.051
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24890270, KAKENHI-PROJECT-26860376
[Journal Article] Indoleamine 2,3-dioxygenase 1 is upregulated in activated microglia in mice cerebellum during acute viral encephalitis.2014
- Author(s)
  Taguchi A, Niwa M, Hoshi M, Saito K, Masutani T, Hisamatsu K, Kobayashi K, Hatano Y, Tomita H, Hara A.
- Journal Title
  
  Neurosci Lett
  
  Volume: 564 Pages: 120-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24890270
[Journal Article] Blockade of indoleamine 2,3-dioxygenase reduces mortality from peritonitis and sepsis in mice by regulating functions of CD11b+ peritoneal cells.2014
- Author(s)
  Hoshi M, Osawa Y, Ito H, Ohtaki H, Ando T, Takamatsu M, Hara A, Saito K, Seishima M.
- Journal Title
  
  Infect Immun.
  
  Volume: 82(11) Issue: 11 Pages: 4487-95
- DOI
  10.1128/iai.02113-14
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26860376
[Journal Article] Kynurenine production mediated by indoleamine 2, 3-dioxygenase aggravates liver injury in HBV-specific CTL-induced fulminant hepatitis2014
- Author(s)
  Ohtaki H, Ito H, Ando K, Ishikawa T, Hoshi M, Ando T, Takamatsu M, Hara A, Moriwaki H, Saito K, Seishima M
- Journal Title
  
  Biochim Biophys Acta
  
  Volume: 1842(9) Issue: 9 Pages: 1464-71
- DOI
  10.1016/j.bbadis.2014.04.015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390149, KAKENHI-PROJECT-24659361, KAKENHI-PROJECT-26860376
[Journal Article] Kynurenine production mediated by indoleamine 2,3-dioxygenase aggravates liver injury in HBV-specific CTL-induced fulminant hepatitis2014
- Author(s)
  Ohtaki H, Ito H, Ando K, Ishikawa T, Hoshi M, Ando T, Takamatsu M, Hara A, Moriwaki H, Saito K, Seishima M
- Journal Title
  
  Biochim Biophys Acta
  
  Volume: S0925-4439(14) Pages: 102-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24890270
[Journal Article] Tumor necrosis factor-α promotes cholestasis-induced liver fibrosis in the mouse through tissue inhibitor of metalloproteinase-1 production in hepatic stellate cells.2013
- Author(s)
  Osawa Y, Hoshi M, Yasuda I, Saibara T, Moriwaki H, Kozawa O.
- Journal Title
  
  PLoS One
  
  Volume: 8(6)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24890270
[Journal Article] Tumor necrosis factor-α promotes cholestasis-induced liver fibrosis in the mouse through tissue inhibitor of　metalloproteinase-1 production in hepatic stellate cells．2013
- Author(s)
  Osawa Y,Saibara T et.al
- Journal Title
  
  PloS One
  
  Volume: 8（6） Issue: 6 Pages: e65251-e65251
- DOI
  10.1371/journal.pone.0065251
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590979, KAKENHI-PROJECT-23591013, KAKENHI-PROJECT-24590981, KAKENHI-PROJECT-24890270, KAKENHI-PROJECT-25460999, KAKENHI-PROJECT-221S0001
[Journal Article] IDO1 plays an immunosuppressive role in 2,4,6-trinitrobenzene sulfate-induced colitis in mice.2013
- Author(s)
  Takamatsu M, Hirata A, Ohtaki H, Hoshi M, Hatano Y, Tomita H, Kuno T, Saito K, Hara A.
- Journal Title
  
  J Immunol
  
  Volume: 191(6) Pages: 3057-64
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24890270
[Journal Article] [Indoleamine 2,3-dioxygenase 1 modulates the immuneresponse; the new therapeutic targets of this drug].2013
- Author(s)
  Yamamoto Y, Murakami Y, Hoshi M, Saito K.
- Journal Title
  
  Nihon Yakurigaku Zasshi
  
  Volume: 142(2) Pages: 85-8
- NAID
  10031190742
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24890270
[Journal Article] IDO1 plays an immunosuppressive role in 2, 4, 6-trinitrobenzene sulfate-induced colitis in mice2013
- Author(s)
  Takamatsu M, Hirata A, Ohtaki H, Hoshi M, Hatano Y, Tomita H, Kuno T, Saito K, Hara A
- Journal Title
  
  J Immunol
  
  Volume: 15;191(6) Issue: 6 Pages: 3057-64
- DOI
  10.4049/jimmunol.1203306
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390149, KAKENHI-PROJECT-24790381, KAKENHI-PROJECT-24890270
[Journal Article] Remarkable role of indoleamine 2, 3-dioxygenase and tryptophan metabolites in infectious diseases : potential role in macrophage-mediated inflammatory diseases2013
- Author(s)
  Murakami Y, Hoshi M, Imamura Y, Arioka Y, Yamamoto Y, Saito K
- Journal Title
  
  Mediators Inflamm
  
  Volume: 2013 Pages: 391984-391984
- DOI
  10.1155/2013/391984
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390149, KAKENHI-PROJECT-23790621, KAKENHI-PROJECT-24592734, KAKENHI-PROJECT-24890270
[Journal Article] Suppression of azoxymethane-induced colonic preneoplastic lesions in rats by 1-methyltryptophan, an inhibitor of indoleamine 2, 3-dioxygenase2012
- Author(s)
  Ogawa K, Hara T, Shimizu M, Ninomiya S, Nagano J, Sakai H, Hoshi M, Ito H, Tsurumi H, Saito K, Seishima M, Tanaka T, Moriwaki H
- Journal Title
  
  Cancer Sci
  
  Volume: 103 Issue: 5 Pages: 951-958
- DOI
  10.1111/j.1349-7006.2012.02237.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590838, KAKENHI-PROJECT-24890270
[Journal Article] High susceptibility to lipopolysaccharide-induced lethal shock in encephalomyocarditis virus-infected mice2012
- Author(s)
  Ohtaki H
- Journal Title
  
  Sci Rep.
  
  Volume: 2 Issue: 1 Pages: 367-375
- DOI
  10.1038/srep00367
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790787, KAKENHI-PROJECT-24890270
[Journal Article] L-tryptophan-kynurenine pathway metabolites regulate type 1 IFNs of acute viral myocarditis in mice2012
- Author(s)
  Hoshi M
- Journal Title
  
  J Immunol
  
  Volume: 188 Issue: 8 Pages: 3980-3987
- DOI
  10.4049/jimmunol.1100997
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390179, KAKENHI-PROJECT-23390149, KAKENHI-PROJECT-23790787, KAKENHI-PROJECT-24890270
[Journal Article] Pre-administration of L-tryptophan improved ADR-induced early renal failure in mice2012
- Author(s)
  Arioka Y
- Journal Title
  
  Life Sci
  
  Volume: 59 Issue: 3-4 Pages: 100-106
- DOI
  10.1016/j.lfs.2012.06.018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390179, KAKENHI-PROJECT-23390149, KAKENHI-PROJECT-24890270
[Journal Article] Studies on tissue and cellular distribution of indoleamine 2, 3-dioxygenase 2 : the absence of IDO1 upregulates IDO2 expression in the epididymis2012
- Author(s)
  Fukunaga M, Yamamoto Y, Kawasoe M, Arioka Y, Murakami Y, Hoshi M, Saito K
- Journal Title
  
  J Histochem Cytochem
  
  Volume: 60(11) Issue: 11 Pages: 854-60
- DOI
  10.1369/0022155412458926
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390149, KAKENHI-PROJECT-24890270
[Journal Article] Inhibition of increased indoleamine 2, 3-dioxygenase activity attenuates Toxoplasma gondii replication in the lung during acute infection2012
- Author(s)
  Murakami Y, Hoshi M, Hara A, Takemura M, Arioka Y, Yamamoto Y, Matsunami H, Funato T, Seishima M, Saito K
- Journal Title
  
  Cytokine
  
  Volume: 59(2) Issue: 2 Pages: 245-51
- DOI
  10.1016/j.cyto.2012.04.022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390149, KAKENHI-PROJECT-24890270
[Journal Article] -Epigallocatechin gallate inhibits the expression of indoleamine 2,3-dioxygenase in human colorectal cancer cells2012
- Author(s)
  Ogawa K, Hara T, Shimizu M, Nagano J, Ohno T, Hoshi M, Ito H, Tsurumi H, Saito K, Seishima M, Moriwaki H
- Journal Title
  
  Oncol Lett
  
  Volume: 4(3) Pages: 546-550
- URL
  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3673646/
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24890270
[Patent] ＫＡＴ阻害活性を有する化合物を含有するがん治療用組成物2019
- Inventor(s)
  星雅人
- Industrial Property Rights Holder
  星雅人
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-17K15785
[Patent] Ｄ－サイクロセリンまたはその塩を含有するがん治療用組成物2018
- Inventor(s)
  星　雅人
- Industrial Property Rights Holder
  星　雅人
- Industrial Property Rights Type
  特許
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-17K15785
[Presentation] CD8＋制御性T細胞はLPS誘導性敗血症の重症化を抑制する2022
- Author(s)
  森田那奈架、星　雅人、手塚裕之、吉田清賀、佐藤史明、横井浩幸、斎藤邦明
- Organizer
  第54回藤田医科大学医学会学術集会
- Data Source
  KAKENHI-PROJECT-20K07432
[Presentation] Involvement of cerebellum blood-brain barrier in the depression-like behaviors induced by chronic social defeat stress.2021
- Author(s)
  Aika Kosuge, Kazuo Kunisawa, Hiroyuki Tezuka, Masato Hoshi, Nanaka Morita, Yasuko Yamamoto, Kuniaki Saito, Toshitaka Nabeshima, Akihiro Mouri
- Organizer
  第64回日本神経化学会
- Data Source
  KAKENHI-PROJECT-20K07432
[Presentation] びまん性大細胞型B細胞リンパ腫の生存率はキヌレニン-3-モノオキシゲナーゼにより制御される2021
- Author(s)
  森田那奈架、星　雅人、吉田清賀、佐藤史明、斎藤邦明
- Organizer
  第40回JSTRY
- Data Source
  KAKENHI-PROJECT-20K07432
[Presentation] HILIC-ESI-MS/MSによる希少糖ヌクレオチドの探索2021
- Author(s)
  中嶋和紀、木下充弘、星雅人、髙橋和男
- Organizer
  第40回日本糖質学会
- Data Source
  KAKENHI-PROJECT-20K07432
[Presentation] The deficit of quinolinic acid phosphoribosyltransferase induces hypolocomotion and cognitive impairment through impairment of dopaminergic neuronal function2019
- Author(s)
  Moe Niijima, Akihiro Mouri, Tomoaki Teshigawara, Kazuo Kunisawa, Hisayoshi Kubota, Mami Hirakawa, Yuko Mori, Masato Hoshi, Yasuko Yamamoto, Toshitaka Nabeshima, Kuniaki Saito
- Organizer
  AsCNP
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15785
[Presentation] Kynurenine Plays an Immunosuppressive Role in 2,4,6-Trinitrobenzene Sulfate-Induced Colitis in Mice2018
- Author(s)
  Masato Hoshi
- Organizer
  15th International Society for Tryptophan Reserch
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15785
[Presentation] マウス致死性敗血症モデルにおけるインドールアミン酸素添加酵素の役割について2016
- Author(s)
  星　雅人久保　緋紗子　毛利　彰宏　勅使河原　知明　山菅　和可奈　和田　直也　山本　康子　鍋島　俊隆　齋藤　邦明
- Organizer
  第37回日本トリプトファン研究会学術集会
- Place of Presentation
  東京農業大学、東京都世田谷区
- Year and Date
  2016-12-10
- Data Source
  KAKENHI-PROJECT-26860376
[Presentation] Absence of kynurenine 3-monooxygenase reduces mortality of acute viral myocarditis in mice2016
- Author(s)
  久保　緋紗子　星　雅人　毛利　彰宏　勅使河原　知明　山菅　和可奈　和田　直也　山本　康子　鍋島　俊隆　齋藤　邦明
- Organizer
  第37回日本トリプトファン研究会学術集会
- Place of Presentation
  東京農業大学、東京都世田谷区
- Year and Date
  2016-12-10
- Data Source
  KAKENHI-PROJECT-26860376
[Presentation] Blockade of Indoleamine 2,3-dioxygenase reduces mortality from peritonitis and sepsis in mice by regulating function of CD11b+ peritoneal cells2015
- Author(s)
  Masato Hoshi, Yosuke Osawa, Hiroyasu Ito, Mituru Seishima, Kuniaki Saito
- Organizer
  14th International Society for Tryptophan Research
- Place of Presentation
  Grand Rapids, USA
- Year and Date
  2015-09-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860376
[Presentation] A rapid and highly sensitive method to evaluate the quinolinic acid using recombinant enzymes with HPLC-Fluorescence detection2015
- Author(s)
  Hidetsugu Fujigaki, Akiko Sakamoto-Morise, Suwako Fujigaki, Kanako Hirabayashi-Takahashi, Masato Hoshi, Yasuko Yamamoto, Sanford P. Markey, and Kuniaki Saito
- Organizer
  14th International Society for Tryptophan Research
- Place of Presentation
  Grand Rapids, USA
- Year and Date
  2015-09-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860376
[Presentation] L-Tryptophan-kynurenine pathway metabolites regulate type I IFNs following viral infections2012
- Author(s)
  Hoshi M
- Organizer
  13th International Society for Tryptophan Research
- Place of Presentation
  Sydney, Australia
- Data Source
  KAKENHI-PROJECT-24890270

1. SAITO Kuniaki (80262765)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
2. SEISHIMA Mitsuru (10171315)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
3. Kondo Masashi (00378077)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 山本康子 (00331869)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
5. 藤垣英嗣 (00612631)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
6. 毛利彰宏 (20597851)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. 山本直樹 (00267957)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 今泉和良 (50362257)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 佐藤光夫 (70467281)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. ITO Hiroyasu

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
11. HARA Akira

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
12. SHIMIZU Masahito

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. MURAKAMI Yuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
14. 手塚裕之

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
15. 斉藤邦明

# of Collaborated Projects: 0 results

# of Collaborated Products: 13 results
16. 森脇久隆

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 西原利治

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 宮崎龍彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hoshi Masato 星 雅人

HOSHI Masato 星 雅人

Research Projects

Research Products

Co-Researchers

希少糖を用いた制御性T細胞の新規分化誘導機構の解明と機能的応用Principal Investigator

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Targeting Tryptophan Metabolism for Immune Regulation of Sepsis and Novel Therapeutic StrategiesPrincipal Investigator

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analysis of lung cancer immunotherapy targeting tryptophan metabolism

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Relationship between changes in amino acid metabolism during pregnancy and postpartum depression.

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Establishment and pathological analysis of novel immunotherapy by control of tryptophan-metabolizing enzymes in metastatic tumorsPrincipal Investigator

Principal Investigator

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The effects of NKT cell-mediated immunotherapy by IDO inhibitor in mouse lung metastasis modelPrincipal Investigator

Principal Investigator

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The investigation of immune regulation by IDO in NKT cell-mediated immunotherapyPrincipal Investigator

Principal Investigator

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[Journal Article] D-allose enhances the efficacy of hydroxychloroquine against Lewis lung carcinoma cell growth by inducing autophagy2022

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[Journal Article] Absence of indoleamine 2,3?dioxygenase 2 promotes liver regeneration after partial hepatectomy in mice2022

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[Journal Article] 3-Hydroxykynurenine Regulates Lipopolysaccharide-Stimulated IL-6 Production and Protects against Endotoxic Shock in Mice2021

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[Journal Article] Viability of diffuse large B-cell lymphoma cells is regulated by kynurenine 3-monooxygenase activity2021

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[Journal Article] Evaluation of red blood cell parameters provided by the UF-5000 urine auto-analyzer in patients with glomerulonephritis282021

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[Journal Article] Kynurenine 3-monooxygenase deficiency induces depression-like behavior via enhanced antagonism of α7 nicotinic acetylcholine receptors by kynurenic acid2021

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[Journal Article] Kynurenine plays an immunosuppressive role in 2,4,6-trinitrobenzene sulfate-induced colitis in mice.2020

Author(s)

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Hoshi Masato 星雅人

HOSHI Masato 星雅人