EHARA Tsuguhisa 頴原嗣尚

Researcher Number	50037446
Other IDs
Affiliation *help	2003 – 2007 : Saga University, Faculty of Medicine, Professor, 医学部, 教授 1996 – 2002 : 佐賀医科大学, 医学部, 教授 1994 : 佐賀医科大学, 医学部, 教授 1989 – 1992 : Saga Medical School, Dept. of Physiology Professor, 医学部, 教授 1987 – 1988 : Kyushu Univ., Fac. Med., Associate Professor, 医学部, 助教授 1986 : 九大, 医学部, 助教授
Review Section/Research Field	Principal Investigator General physiology / Neurophysiology and muscle physiology / Neurophysiology and muscle physiology Except Principal Investigator General physiology / General physiology
Keywords	Principal Investigator 心筋細胞 / CFTR / ATP / クロライドチャネル / RVD / PKC / PKA / 心筋 / chloride current / 燐酸化 … More Except Principal Investigator 膜電位感受性色素 / クロライド電流 / ATP感受性Kチャネル / 心筋細胞 / Kir2.1 / カリウムチャネル / ランダウン / 洞結節異常自動能 / polyamine / Potassium channel / イオン感受性電極 / 心筋虚血 / 伸展活性化チャネル / 内向き整流性カリウム電流 / inward rectifier potassium current / cardiac myocyte / 内向き整流カリウムチャネル / potassium channel / イオンチャネル / マグネシウムイオン / potassium current / magnesium ion / 細胞内カルシウム濃度 / アミロライド / リゾフォスファチジ-ルコリン / プリン作動性チャネル / 心筋 / カリウムイオン / イオン電流 / 異方向性伝導 / カリウム電流 / 内向き整流カリウム電流 / Cardiac myocyte / ポリアミン / ATP感受性カリウム電流 / 短鎖アシルカルニチン / 興奮伝播マッピング / トリプシン / Inward rectifier potassium current / ion channel / 交感神経緊張 / コンピューターモデル Less

Regulation of by protein kinases of CFTR chloride current and the acidic pH-activated chloride current in cardiac myocytesPrincipal Investigator
- Principal Investigator
  
  EHARA Tsuguhisa
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurophysiology and muscle physiology
- Research Institution
  Saga University
A study on the molecular basis of the cardiac inward rectifier potassium channels
- Principal Investigator
  
  YANAGI Keiko
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Saga University
  佐賀医科大学
Regulation of cell-volume and intracellular osmolarity by chloride channels in cardiac cellsPrincipal Investigator
- Principal Investigator
  
  RHARA Tsuguhisa
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Saga University
Study on the diversity of the cardiac inward rectifier potassium channels
- Principal Investigator
  
  YANAGI(ISHIHARA)
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Saga Medical School
Regulation of cell-volume and cytoplasmic content of solutes by CFTR Cl Channel in cardiac cellsPrincipal Investigator
- Principal Investigator
  
  EHARA Tsuguhisa
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Saga Medical School
Novel physiological function of cardiac beta-adrenoceptor-dependent chloride channelPrincipal Investigator
- Principal Investigator
  
  EHARA Tsuguhisa
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Saga Medical School
心筋細胞のβ受容体依存性クロライドチャネルの調節機構の解明Principal Investigator
- Principal Investigator
  
  頴原嗣尚
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  佐賀医科大学
心筋細胞のcyclic AMP依存性クロライドチャネル調節機構の解明Principal Investigator
- Principal Investigator
  
  頴原嗣尚
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  佐賀医科大学
心筋の異常興奮と伝導のメカニズム
- Principal Investigator
  
  有田真
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  大分医科大学
心筋の異常興奮と伝導のメカニズム
- Principal Investigator
  
  有田真
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  大分医科大学
Properties and regulation of cardiac chloride currentPrincipal Investigator
- Principal Investigator
  
  EHARA Tsuguhisa
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Neurophysiology and muscle physiology
- Research Institution
  Saga Medical School
心筋の異常興奮と伝導のメカニズム
- Principal Investigator
  
  有田真
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  大分医科大学
An electrophysiological study on miniature Ca relelase from the sarcoplasmic reticulum in cardiac myocytes.Principal Investigator
- Principal Investigator
  
  EHARA Tsuguhisa
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Saga Medical School
  Kyushu University
Electrophysiological study on the physiological roles of the oscillatory release of calcium from the sarcoplasmic reticulum in myocardium.Principal Investigator
- Principal Investigator
  
  EHARA Tsuguhisa
- Project Period (FY)
  1986 – 1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Kyushu University

All 2005 2004

All Journal Article

[Journal Article] Different intracellular polyamine concentrations underlie the difference in the inward rectifier K^+ currents in atria and ventricles of the guinea-pig heart.2005
- Author(s)
  Yan D-H, Nishimura K, Yoshida K, Nakahira K, Ehara T, Igarashi K, Ishihara K.
- Journal Title
  
  Journal of Physiology (London) 563
  
  Pages : 713-724
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590187
[Journal Article] Two modes of polyamine block regulating the cardiac inward rectifier K^+ current I_<K1> as revealed by a study of the Kir2.1 channel expressed in a human cell line.2004
- Author(s)
  Ishihara K, Ehara T.
- Journal Title
  
  Journal of Physiology (London) 556
  
  Pages : 61-78
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590187
[Journal Article] Cell-volume regulation by swelling-activated chloride current in guinea-pig ventricular myocytes.2004
- Author(s)
  Yamamoto, S, Ishihara, K, Ehara, T, Shioya, T.
- Journal Title
  
  Japanese Journal of Physiology 54
  
  Pages : 31-38
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590187

1. SHIOYA Takao (20253594)

# of Collaborated Projects : 3results

# of Collaborated Products : 0results
2. 有田真 (60037364)

# of Collaborated Projects : 3results

# of Collaborated Products : 0results
3. 神野耕太郎 (40025630)

# of Collaborated Projects : 3results

# of Collaborated Products : 0results
4. 小川聡 (90124940)

# of Collaborated Projects : 3results

# of Collaborated Products : 0results
5. 平岡昌和 (80014281)

# of Collaborated Projects : 3results

# of Collaborated Products : 0results
6. YANAGI(ISHIHARA) (70265990)

# of Collaborated Projects : 2results

# of Collaborated Products : 3results
7. ONO Kyouichi (70185635)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
8. YAMAMOTO Shintaro (40336110)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
9. 西勝英 (00040220)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
10. MATSUURA Hiroshi (60238962)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
11. MATSUBAYASHI Taro (10304883)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
12. 渡部良夫 (70084572)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results

EHARA Tsuguhisa 頴原 嗣尚

Research Projects

Research Products

Co-Researchers

Regulation of by protein kinases of CFTR chloride current and the acidic pH-activated chloride current in cardiac myocytesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A study on the molecular basis of the cardiac inward rectifier potassium channels

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Regulation of cell-volume and intracellular osmolarity by chloride channels in cardiac cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study on the diversity of the cardiac inward rectifier potassium channels

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Regulation of cell-volume and cytoplasmic content of solutes by CFTR Cl Channel in cardiac cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Novel physiological function of cardiac beta-adrenoceptor-dependent chloride channelPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

心筋細胞のβ受容体依存性クロライドチャネルの調節機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

心筋細胞のcyclic AMP依存性クロライドチャネル調節機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

心筋の異常興奮と伝導のメカニズム

Principal Investigator

Project Period (FY)

Research Category

Research Institution

心筋の異常興奮と伝導のメカニズム

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Properties and regulation of cardiac chloride currentPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

心筋の異常興奮と伝導のメカニズム

Principal Investigator

Project Period (FY)

Research Category

Research Institution

An electrophysiological study on miniature Ca relelase from the sarcoplasmic reticulum in cardiac myocytes.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Electrophysiological study on the physiological roles of the oscillatory release of calcium from the sarcoplasmic reticulum in myocardium.Principal Investigator

EHARA Tsuguhisa 頴原嗣尚