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EHARA Tsuguhisa  頴原 嗣尚

ORCIDConnect your ORCID iD *help
Researcher Number 50037446
Other IDs
Affiliation *help 2005 – 2007 : 佐賀大, 医学部, 教授
2003 – 2007 : Saga University, Faculty of Medicine, Professor, 医学部, 教授
2002 – 2003 : 佐賀医大, 医学部, 教授
1996 – 2002 : 佐賀医科大学, 医学部, 教授
1996 – 2000 : 佐賀医大, 医学部, 教授 … More
1994 : 佐賀医科大学, 医学部, 教授
1989 – 1992 : Saga Medical School, Dept. of Physiology Professor, 医学部, 教授
1987 – 1988 : Kyushu Univ., Fac. Med., Associate Professor, 医学部, 助教授
1986 : 九大, 医学部, 助教授 Less
Review Section/Research Field
Principal Investigator
General physiology / Neurophysiology and muscle physiology / Neurophysiology and muscle physiology
Except Principal Investigator
General physiology / General physiology
Keywords
Principal Investigator
心筋細胞 / CFTR / ATP / 心筋 / クロライドチャネル / RVD / PKC / PKA / furosemide / 燐酸化 … More / K-Cl cotransporter / カフェイン / cardiac cell / P2プリン受容体 / chloride current / pH / 筋小胞体 / bumetanide / cell-volume regulation / chloride channel / Na-K-2Cl cotransporter / 細胞容積 / クロライド電流 / チャネルキネチックス / 膜電位 / αアドレナリン作用 / whole cell recording / アドレナリン / βアドレナリン作用 / 小胞体 / カルシウム放出 / マウス / Myocardium / Cardiac myocvtes / 非選択性陽イオンチャネル / パッチクランプ / 酸性pH誘発膜電流 / ventricular cell / 容積感受性クロライド電流 / マグネシウム / P2-purinergic receptor / cyclic AMP / モルモット / カルシウムホメオスタシス / α-受容体 / caffeine / 細胞容積調節 / Calcium-mediated conductance / Purine receptor / sarcoplasmic reticulum / DIDS / Chloride channel / Ca依存性陽イオンチャネル / ムスカリン受容体 / Cardiac muscle / 容積感受性Cl電流 / プリンレセプタ- / Cyclic AMP / イオンチャネル / クロライド チャネル / swelling-activated RVS current / Muscarinic receptor / 開確率 / cell-swelling / Ca^<2+>-mediated ion channel / Ca排出 / 膜電流 / Calcium homeostasis / 細胞内カルシウム / 調節性容量減少 / カルシウム排出機構 / guinea-pig / Oscillatory release of calcium / Sarcoplasmic reticulum / Chloride current / Ca放出 / P2 purinoceptor / プリン受容体 / 心室筋細胞 / β-受容体 / acidic pH-induced current / Ca release / P_<2Y>受容体 / サイクリックAMP … More
Except Principal Investigator
膜電位感受性色素 / クロライド電流 / ATP感受性Kチャネル / 心筋細胞 / Kir2.1 / カリウムチャネル / ランダウン / 洞結節異常自動能 / polyamine / Potassium channel / イオン感受性電極 / 心筋虚血 / 伸展活性化チャネル / 内向き整流性カリウム電流 / inward rectifier potassium current / cardiac myocyte / 内向き整流カリウムチャネル / potassium channel / イオンチャネル / マグネシウムイオン / potassium current / magnesium ion / 細胞内カルシウム濃度 / アミロライド / リゾフォスファチジ-ルコリン / プリン作動性チャネル / 心筋 / カリウムイオン / イオン電流 / 異方向性伝導 / カリウム電流 / 内向き整流カリウム電流 / Cardiac myocyte / ポリアミン / ATP感受性カリウム電流 / 短鎖アシルカルニチン / 興奮伝播マッピング / トリプシン / Inward rectifier potassium current / ion channel / 交感神経緊張 / コンピューターモデル Less
  • Research Projects

    (14results)
  • Research Products

    (3results)
  • Co-Researchers

    (12People)
  •  Regulation of by protein kinases of CFTR chloride current and the acidic pH-activated chloride current in cardiac myocytesPrincipal Investigator

    • Principal Investigator
      EHARA Tsuguhisa
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurophysiology and muscle physiology
    • Research Institution
      Saga University
  •  A study on the molecular basis of the cardiac inward rectifier potassium channels

    • Principal Investigator
      YANAGI Keiko
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General physiology
    • Research Institution
      Saga University
      佐賀医科大学
  •  Regulation of cell-volume and intracellular osmolarity by chloride channels in cardiac cellsPrincipal Investigator

    • Principal Investigator
      RHARA Tsuguhisa
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General physiology
    • Research Institution
      Saga University
  •  Study on the diversity of the cardiac inward rectifier potassium channels

    • Principal Investigator
      YANAGI(ISHIHARA)
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General physiology
    • Research Institution
      Saga Medical School
  •  Regulation of cell-volume and cytoplasmic content of solutes by CFTR Cl Channel in cardiac cellsPrincipal Investigator

    • Principal Investigator
      EHARA Tsuguhisa
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General physiology
    • Research Institution
      Saga Medical School
  •  Novel physiological function of cardiac beta-adrenoceptor-dependent chloride channelPrincipal Investigator

    • Principal Investigator
      EHARA Tsuguhisa
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General physiology
    • Research Institution
      Saga Medical School
  •  心筋細胞のβ受容体依存性クロライドチャネルの調節機構の解明Principal Investigator

    • Principal Investigator
      頴原 嗣尚
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General physiology
    • Research Institution
      佐賀医科大学
  •  心筋細胞のcyclic AMP依存性クロライドチャネル調節機構の解明Principal Investigator

    • Principal Investigator
      頴原 嗣尚
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      General physiology
    • Research Institution
      佐賀医科大学
  •  心筋の異常興奮と伝導のメカニズム

    • Principal Investigator
      有田 真
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      大分医科大学
  •  心筋の異常興奮と伝導のメカニズム

    • Principal Investigator
      有田 真
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      大分医科大学
  •  Properties and regulation of cardiac chloride currentPrincipal Investigator

    • Principal Investigator
      EHARA Tsuguhisa
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Neurophysiology and muscle physiology
    • Research Institution
      Saga Medical School
  •  心筋の異常興奮と伝導のメカニズム

    • Principal Investigator
      有田 真
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      大分医科大学
  •  An electrophysiological study on miniature Ca relelase from the sarcoplasmic reticulum in cardiac myocytes.Principal Investigator

    • Principal Investigator
      EHARA Tsuguhisa
    • Project Period (FY)
      1988 – 1989
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      General physiology
    • Research Institution
      Saga Medical School
      Kyushu University
  •  Electrophysiological study on the physiological roles of the oscillatory release of calcium from the sarcoplasmic reticulum in myocardium.Principal Investigator

    • Principal Investigator
      EHARA Tsuguhisa
    • Project Period (FY)
      1986 – 1987
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      General physiology
    • Research Institution
      Kyushu University

All 2005 2004

All Journal Article

  • [Journal Article] Different intracellular polyamine concentrations underlie the difference in the inward rectifier K^+ currents in atria and ventricles of the guinea-pig heart.2005

    • Author(s)
      Yan D-H, Nishimura K, Yoshida K, Nakahira K, Ehara T, Igarashi K, Ishihara K.
    • Journal Title

      Journal of Physiology (London) 563

      Pages : 713-724

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590187
  • [Journal Article] Two modes of polyamine block regulating the cardiac inward rectifier K^+ current I_<K1> as revealed by a study of the Kir2.1 channel expressed in a human cell line.2004

    • Author(s)
      Ishihara K, Ehara T.
    • Journal Title

      Journal of Physiology (London) 556

      Pages : 61-78

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590187
  • [Journal Article] Cell-volume regulation by swelling-activated chloride current in guinea-pig ventricular myocytes.2004

    • Author(s)
      Yamamoto, S, Ishihara, K, Ehara, T, Shioya, T.
    • Journal Title

      Japanese Journal of Physiology 54

      Pages : 31-38

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590187
  • 1.  SHIOYA Takao (20253594)
    # of Collaborated Projects : 3results
    # of Collaborated Products : 0results
  • 2.  有田 真 (60037364)
    # of Collaborated Projects : 3results
    # of Collaborated Products : 0results
  • 3.  神野 耕太郎 (40025630)
    # of Collaborated Projects : 3results
    # of Collaborated Products : 0results
  • 4.  小川 聡 (90124940)
    # of Collaborated Projects : 3results
    # of Collaborated Products : 0results
  • 5.  平岡 昌和 (80014281)
    # of Collaborated Projects : 3results
    # of Collaborated Products : 0results
  • 6.  YANAGI(ISHIHARA) (70265990)
    # of Collaborated Projects : 2results
    # of Collaborated Products : 3results
  • 7.  ONO Kyouichi (70185635)
    # of Collaborated Projects : 2results
    # of Collaborated Products : 0results
  • 8.  YAMAMOTO Shintaro (40336110)
    # of Collaborated Projects : 2results
    # of Collaborated Products : 0results
  • 9.  西 勝英 (00040220)
    # of Collaborated Projects : 2results
    # of Collaborated Products : 0results
  • 10.  MATSUURA Hiroshi (60238962)
    # of Collaborated Projects : 1results
    # of Collaborated Products : 0results
  • 11.  MATSUBAYASHI Taro (10304883)
    # of Collaborated Projects : 1results
    # of Collaborated Products : 0results
  • 12.  渡部 良夫 (70084572)
    # of Collaborated Projects : 1results
    # of Collaborated Products : 0results

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