Ohno Hiroshi 大野博司

… Alternative Names

OHNO Hiroshi 大野博司

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Researcher Number	50233226
Other IDs	https://orcid.org/0000-0001-8776-9661
External Links
Affiliation (Current)	2025: 国立研究開発法人理化学研究所, 生命医科学研究センター, チームディレクター
Affiliation (based on the past Project Information) *help	2018 – 2024: 国立研究開発法人理化学研究所, 生命医科学研究センター, チームリーダー 2015 – 2018: 国立研究開発法人理化学研究所, 統合生命医科学研究センター, グループディレクター 2017: 国立研究開発法人理化学研究所, その他, 研究員 2017: 理化学研究所, 生命医科学研究センター, チームリーダー 2017: 理化学研究所, 総合生命医科学研究センター, グループディレクター … More 2015: 国立研究開発法人理化学研究所, その他部局等, その他 2013 – 2014: 独立行政法人理化学研究所, 統合生命医科学研究センター, グループディレクター 2012: 理化学研究所, 免疫系構築研究チーム, チームリーダー 2004 – 2012: 独立行政法人理化学研究所, 免疫系構築研究チーム, チームリーダー 2007: The Institute of Physical and Chemical Research, 免疫系構築研究チーム, チームリーダー 2006: 独立行政法人理化学研究所, 免疫糸構築研究チーム, チームリーダー 1999 – 2003: Kanazawa Univ., Cancer. Research Inst. Professor, がん研究所, 教授 1998: 千葉大学, 医学研究科, 助教授 1998: 千葉大学, 大学院・医学研究科, 助教授 1998: 千葉大学, 大学院・医学系研究科, 助教授 1997: Chiba Univ., Sch.of Med., Associate Professor, 医学部, 助教授 1992 – 1993: 千葉大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Biological Sciences / Immunology / Medium-sized Section 49:Pathology, infection/immunology, and related fields / Structural biochemistry / Basic Section 53010:Gastroenterology-related / Structural biochemistry / Biological Sciences / Nerve anatomy/Neuropathology / Cell biology / Immunology … More Except Principal Investigator … More Immunology / Biological Sciences / Biological Sciences / Basic Section 57030:Conservative dentistry-related / Medium-sized Section 57:Oral science and related fields / Immunology / Periodontology / Integrative animal science / Psychiatric science / Digestive surgery Less
Keywords	Principal Investigator 遺伝子欠損マウス / 細胞・組織 / M細胞 / AP複合体 / 上皮細胞 / リソソーム / 細胞生物学 / 細胞内輸送 / μ1B / 輸送シグナル … More / エンドサイトーシス / epithelial cells / 腸内細菌 / Spi-B / RANKL / 腸管免疫 / 免疫学 / 蛋白質 / 小胞輸送 / 極性輸送 / ユビキチン / チロシン・シグナル / 大腸炎 / IgA / 統合オミクス解析 / 自己免疫疾患 / 多発性硬化症 / 腸内細菌叢 / SNAP25 / μ3B / selective sorting / AP complexes / 選別輸送 / RANK / 腸管免疫系 / GP2 / 抗原取り込み / 分化 / 輸送小胞 / 細胞内局在 / チロシンモチーフ / ノックアウトマウス / AP-1B / ポリオウイルス受容体 / 分裂軸 / エンドソーム / トランスゴルジ網 / 細胞内蛋白輸送 / Nef / Env / FcRγ / η鎖 / ζ鎖 / ζファミリー / T細胞分化 / T細胞受容体 / 相同組換え / DSS腸炎 / DSS誘導性大腸炎 / Dorea / 炎症性腸疾患 / デキストラン硫酸ナトリウム（DSS）誘導性大腸炎 / Dorea1 / Lactobacillus / 潰瘍性大腸炎 / 腸管バリア / トランス脂肪酸 / 2型糖尿病 / GPR41 / プロピオン酸 / 喘息 / エンドリシン / 小児アレルギー / メタボローム / 糖尿病 / アレルギー / 宿主ー腸内細菌叢相互作用 / 統合オミクス手法 / Th17型Ｔ細胞 / 自己抗原交叉ペプチド / CD8陽性制御性Ｔ細胞 / １型糖尿病 / STZ誘導1型糖尿病 / 実験的自己免疫性脳脊髄炎（EAE) / CD8+制御性Ｔ細胞 / ルミノコッカス属菌 / トレハロース / 寄生虫 / 1型糖尿病 / EAE（実験的自己免疫性脳脊髄炎） / 抗菌ペプチド / NFkB / 濾胞関連上皮（FAE） / GALT / 細菌 / Ｍ細胞 / IL-22BP / 食物抗原 / IL-22 / NF-kB / 濾胞関連上皮 / 腸管関連リンパ組織 / sorting signal / KO mice / gastric acid secretion / neurons / vesicular transport / GABA / てんかんけいれん / 胃酸分泌障害 / 神経細胞 / seizure / axis of cell division / pliovirus receptor / ジ-ロイシン・シグナル / ポリオウィルス受容体 / けいれん / cell polarity / endocytosis / sorting signals / tyrosine-based sorting signal / clathrin / 細胞極性 / チロシンシグナル / クラスリン / サルモネラ / NFκB / 細菌感染 / シグナル伝達 / 発生・分化 / 粘膜免疫学 / b / LTa / Citrobacter rodentium / GPIアンカータンパク質 / Dicer / miRNA / マイクロアレイ / 腸管免疫応答 / トランスサイトーシス / 経口ワクチン / 上皮細胞間Tリンパ球 / 粘膜免疫系 / M-Sec / 上皮細胞極性輸送 / 細胞内ロジスティクス / TNT / M-sec / CCL20 / ケモカイン / FAE / パイエル板 / μ3B遺伝子 / 遺伝子解析 / 遺伝子変異 / 神経疾患 / μ3Bサブユニット / 変異解析 / 遺伝子 / てんかん / ZnT3 / VGAT / CLASP / tGolgin-1 / 欠損マウス / ポストゴルジ / 分泌系 / オルガネラ / 調節性分泌 / オートファジー / 細胞内膜系 / メンブレントラフィック / ポリオ / ウイルス / 感染症 / 腸管上皮細胞 / 感染様式 / ポリオウイルス / Hrs / ジーロイシン・シグナル / 脱感作 / μ2 / AP-2 / マトリックス蛋白 / ペルオキシソーム / ACTE-II / HIV / ジーロシシン・シグナル / antisense法 / gene trap法 / 変異細胞株 / アシルCoAチオエステラーゼ-III / 宿主因子 / HIV-1 … More Except Principal Investigator CTLA-4 / 腸内細菌 / 口腔細菌 / シグナル伝達 / T細胞抗原レセプター / Jak3 / Gab-2 / 全身疾患 / 歯周病 / 歯周病原細菌 / 腸内細菌叢 / Gβγ subunits / epilepsy / temporal lobe epilepsy / kindling / effector / G protein / CAST / E-box / RIT / ARF / GGA / ノックアウトマウス / ITAM / TCR / CD3複合体 / 上皮細胞 / トランスサイトーシス / FAE / 粘膜免疫 / GP2 / パイエル板 / M細胞 / NKR-P1 / チロシンリン酸化 / アダプター複合体 / Co-stimulation / チロシンモチーフ / SHP-2 / リソソーム / T細胞 / 歯周炎 / 口腸連関 / 口ー腸連関 / オーミクス解析 / Treg / 妊娠 / 酪酸 / GPR41 / Aire / 胸腺 / 制御性T細胞 / 短鎖脂肪酸 / 食物繊維 / 神経変性疾患 / 脳神経疾患 / 遺伝子 / 生理学 / 細胞・組織 / 蛋白質 / 細胞内分解 / オートファジー / 関節リウマチ / 非感染性疾患 / ペリオドンタルメディスン / dysbiosis / 代謝性疾患 / 前頭葉 / 中枢 / 母性 / グルココルチコイド / 腸内免疫 / 内分泌 / BDNF / 早期離乳 / うう様行動 / 細菌叢 / 免疫 / ストレス / 母子間 / マウス / βadrenergic receptor kinase / G protein-gated inward rectifier potassium channel / 細胞内情報伝達 / GIRK / キンドリング / てんかん / βγサブユット / G蛋白質 / βadrenaline receptor kinase / G protein-gated inwawd rectifier potassium channel / Knockout mouse / pre T cell receptor / TCR signal / 活性化制御 / シグナル伝達系 / 胸腺細胞選択 / Jakキナーゼ / CD3結合分子 / 胸腺分化 / ZAP-70 / rap-1 / 分泌リソソーム / 免疫抑制 / プレT細胞レセプター / TCRシグナル / mannose 6-phosphate receptor / γ-synergin / rabaptin-5 / vesicular transtport / adapter / clathrin / チロシン・シグナル / GGAタンパク質 / マンノース6リン酸受容体 / γ-シナージン / ラバプチン5 / 小胞輸送 / アダプター / クラスリン / tyrosine motif / lymphocyte activation / intracellular protein trafficking / AP-complex / CD3ζ chain / μ chain / チロシンシグナル / クラスリン被膜小胞 / 細胞内蛋白輸送 / m鎖 / CD3ζ鎖 / μ鎖 / CDζ鎖 / AP複合体 / 細胞内蛋白誘導 / リンパ球活性化 / T cell differentiation / negative selection / positive / CD3gamma / calnexin / pre-TCR complex / Signal transduction / TCR-CD3複合体 / アビディティーモデル / 遺伝子欠損マウス / 分化 / T細胞分化 / DC3γ / T細胞文化 / ポジティブ・ネガティブ選択 / CD3γ / カルネキシン / プレTCR複合体 / Tyrosine phosphorylation / PLCgamma1 / Signaling motif / TCRbeta dimer expression / CD3zeta family molecules / Intracellular signal transduction mechanism / CD3 complex / T cell antigen receptor / ζダイマーレセプター / シグナルモチーフ / チロシンキナーゼ / ζファミリー分子 / T細胞レセプター / CD3ξファミリー分子 / PLCγ1 / シグナル伝達モチーフ / β鎖単独発現 / CD3ζファミリー分子 / 細胞内シグナル伝達機構 / 治療 / 診断 / 分子特性 / 細胞特性 / 大腸がん / 高次生体システム / 情報科学 / 疾患 / アウトリーチ / 融合研究 / 病態の理解 / 細胞内ロジスティクス / 画像解析 / オルガネラ / 社会還元 / 成果報告 / 情報発信 / 分子細胞生物学 / ケミカルバイオロジー / 情報科学・工学 / 細胞内輸送 / メンブレントラフィック / 大腸菌 / 細菌感染 / Salmonella / PrPC / トランサイトーシス / M-Sec / FcγRIII / CD3ζ / Th2 / Th1 / FcRγ / B6ES細胞株 / NK細胞欠損マウス / キメラマウス / 細胞除去システム / 相同組換え / ジフテリアトキシン / 遺伝子ターゲティング / internalization / μ2 / 抑制性シグナル / シグナル伝達機構 / チロシリン酸化 / ネガティブシグナル / 抗腫瘍免疫 Less

Elucidation of the mechanisms of oral-gut connection in inflammaging induced by periodontitis
- Principal Investigator
  
  山崎和久
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Institute of Physical and Chemical Research
宿主ー腸内細菌叢相互作用が宿主の病理に及ぼす影響の研究Principal Investigator
- Principal Investigator
  
  大野博司
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 49:Pathology, infection/immunology, and related fields
- Research Institution
  Institute of Physical and Chemical Research
The impact of gut microbiota on autoimmune diseasesPrincipal Investigator
- Principal Investigator
  
  Ohno Hiroshi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 49:Pathology, infection/immunology, and related fields
- Research Institution
  Institute of Physical and Chemical Research
腸炎における粘膜障害治癒に関与する腸内細菌の同定とそのメカニズムの解明Principal Investigator
- Principal Investigator
  
  大野博司
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Institute of Physical and Chemical Research
Elucidation of oral-gut association based on Elucidation of oral-gut association based on multi-omics analyzes
- Principal Investigator
  
  Yamazaki Kazuhisa
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  Niigata University
Differentiation and function of M cells, a unique intestinal epithelial cell subset for untigen uptakePrincipal Investigator
- Principal Investigator
  
  Ohno Hiroshi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Immunology
- Research Institution
  Institute of Physical and Chemical Research
Brain-gut axis mechanisms formed by mother-pup interactions for the resilience to stress
- Principal Investigator
  
  Kikusui Takefumi
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Integrative animal science
- Research Institution
  Azabu University
Integrated analysis of perio-systemic association based on the oral-gut connection
- Principal Investigator
  
  Yamazaki Kazuhisa
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Periodontology
- Research Institution
  Niigata University
Maternal high fiber diet during pregnancy and lactation influences regulatory T cell differentiation in offspring in mice
- Principal Investigator
  
  NAKAJIMA Akihito
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Juntendo University
Multidisciplinary research on autophagy: from molecular mechanisms to disease states
- Principal Investigator
  
  Mizushima Noboru
- Project Period (FY)
  2013 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Comprehensive understanding of a unique intestinal epithelial M cells specialized for luminal particulate antigen uptakePrincipal Investigator
- Principal Investigator
  
  OHNO Hiroshi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Immunology
- Research Institution
  The Institute of Physical and Chemical Research
Molecular basis of aberrant cellular pathways in gastrointestinal cancer and its application to diagnosis and treatment
- Principal Investigator
  
  MINAMOTO Toshinari
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Digestive surgery
- Research Institution
  Kanazawa University
Funtion and differentiation of a specialized subset of intestinal epithelial M cellsPrincipal Investigator
- Principal Investigator
  
  OHNO Hiroshi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Immunology
- Research Institution
  The Institute of Physical and Chemical Research
Administration of the group grant "Intracellular logistics: interdisciplinary approaches to pathophysiology of membrane traffic"
- Principal Investigator
  
  YOSHIMORI Tamotsu
- Project Period (FY)
  2008 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
Regulation of mucosal immune system by polarized sorting in epithelial cellsPrincipal Investigator
- Principal Investigator
  
  OHNO Hiroshi
- Project Period (FY)
  2008 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  The Institute of Physical and Chemical Research
腸管特殊上皮M細胞における新規病原体取り込み受容体の同定と細胞内輸送機構の解析
- Principal Investigator
  
  長谷耕二
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The Institute of Physical and Chemical Research
Differentiation and function of M cells, a specialized intestinal epithelial cell type, in the mucosal immune systemPrincipal Investigator
- Principal Investigator
  
  大野博司
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Immunology
- Research Institution
  The Institute of Physical and Chemical Research
パイエル板特殊上皮M細胞による抗原トランスサイトーシスの分子基盤
- Principal Investigator
  
  長谷耕二
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The Institute of Physical and Chemical Research
ポリオウイルス感染におけるポリオウイルス受容体サブタイプおよびM細胞の役割の検討Principal Investigator
- Principal Investigator
  
  大野博司
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kanazawa University
「メンブレントラフィック-分子機構から高次機能への展開」の取りまとめPrincipal Investigator
- Principal Investigator
  
  大野博司
- Project Period (FY)
  2003 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The Institute of Physical and Chemical Research
  Kanazawa University
輸送小胞形成・積み荷蛋白質選別の分子機構とその高次機能における役割Principal Investigator
- Principal Investigator
  
  大野博司
- Project Period (FY)
  2003 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The Institute of Physical and Chemical Research
  Kanazawa University
ヒトてんかん責任遺伝子としてのμ3B遺伝子変異の検索Principal Investigator
- Principal Investigator
  
  大野博司
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  The Institute of Physical and Chemical Research
  Kanazawa University
Analysis of cell-type specific adaptor protein (AP) complexes in cells and organismsPrincipal Investigator
- Principal Investigator
  
  OHNO Hiroshi
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  RIKEN
  Kanazawa University
ポリオウイルス感染におけるM細胞の役割の検討Principal Investigator
- Principal Investigator
  
  大野博司
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kanazawa University
細胞内蛋白輸送系による細胞増殖・悪性化の制御機構の研究Principal Investigator
- Principal Investigator
  
  大野博司
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Kanazawa University
細胞増殖因子受容体のユビキチン化と内在化・脱感作の制御機構の研究Principal Investigator
- Principal Investigator
  
  大野博司
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Kanazawa University
Mechanisms for regulation of intracellular protein sorting mediated by the adaptor protein (AP) complex familyPrincipal Investigator
- Principal Investigator
  
  OHNO Hiroshi
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  Kanazawa University
The contribution of G protein-linked effector molecules and Gβγ subunits in the basic mechanisms of epilepsies
- Principal Investigator
  
  SHIMOYAMA Ichiro, 岩佐博人
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  CHIBA UNIVERSITY
蛋白質のリソソームへの輸送の分子機構Principal Investigator
- Principal Investigator
  
  大野博司
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kanazawa University
HIV NefおよびEnv蛋白に結合する細胞性因子の研究Principal Investigator
- Principal Investigator
  
  大野博司
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  Kanazawa University
NK細胞レセプターを介した抗腫瘍免疫応答の制御
- Principal Investigator
  
  荒瀬尚
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Chiba University
HIV NefおよびEnv蛋白に結合する細胞性因子の研究Principal Investigator
- Principal Investigator
  
  大野博司
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  Chiba University
Gene trap法を用いた新たな細胞内蛋白輸送変異細胞株樹立法の開発Principal Investigator
- Principal Investigator
  
  大野博司
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Cell biology
- Research Institution
  Chiba University
Role of tyrosin-motif for lymphocyte activation
- Principal Investigator
  
  SAITO Takashi
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Immunology
- Research Institution
  Chiba University, Graduate School of Medicine
Roles of clathrin-adaptor-like proteins in intracellular protein traffic.
- Principal Investigator
  
  NAKAYAMA Kazuhisa
- Project Period (FY)
  1998 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (B)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
  University of Tsukuba
Signal transduction regulating the differentiation and the function of T cells
- Principal Investigator
  
  SAITO Takashi
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (A).
- Research Field
  
  Immunology
- Research Institution
  Chiba University
Mechanism of regulation of selective intracellular protein sorting by the family of Adaptor (-like) protein complexesPrincipal Investigator
- Principal Investigator
  
  OHNO Hiroshi
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  Kanazawa University
  Chiba University
抗腫瘍免疫におけるT細胞活性化の抑制
- Principal Investigator
  
  SAITO Takashi
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Chiba University
相同組換えによる特異的細胞除去システムの開発
- Principal Investigator
  
  斉藤隆
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Immunology
- Research Institution
  Chiba University
Regulation of T cell differentiation and selection by TCR signals.
- Principal Investigator
  
  SAITO Takashi
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Immunology
- Research Institution
  Chiba University
T細胞受容体複合体遺伝子の標的組換えマウスを用いた免疫系の発生分化の分子機構Principal Investigator
- Principal Investigator
  
  大野博司
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Chiba University
CD3ζ,η遺伝子欠損マウスを用いたT細胞の分化および活性化の機構Principal Investigator
- Principal Investigator
  
  大野博司
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Chiba University
Structure of and signal transduction through T cell receptor complex
- Principal Investigator
  
  SAITO Takashi
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Immunology
- Research Institution
  CHIBA UNIVERSITY

[Book] 臨床粘膜免疫学2010
- Author(s)
  大野博司
- Publisher
  シナジー
- Data Source
  KAKENHI-PROJECT-21390155
[Book] 臨床粘膜免疫学2010
- Author(s)
  大野博司
- Publisher
  シナジー
- Data Source
  KAKENHI-PLANNED-20113003
[Journal Article] Gut microbiota and fecal metabolites in sustained unresponsiveness by oral immunotherapy in school-age children with cow's milk allergy2024
- Author(s)
  Shibata Ryohei、Itoh Naoka、Nakanishi Yumiko、Kato Tamotsu、Suda Wataru、Nagao Mizuho、Iwata Tsutomu、Yoshida Hideo、Hattori Masahira、Fujisawa Takao、Shimojo Naoki、Ohno Hiroshi
- Journal Title
  
  Allergol. Int.
  
  Volume: 73 Issue: 1 Pages: 126-136
- DOI
  10.1016/j.alit.2023.10.001
- ISSN
  1323-8930, 1440-1592
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22H00452
[Journal Article] The propionate-GPR41 axis in infancy protects from subsequent bronchial asthma onset2023
- Author(s)
  Ito Takashi、Nakanishi Yumiko、Shibata Ryohei、Sato Noriko、Jinnohara Toshi、Suzuki Sayo、Suda Wataru、Hattori Masahira、Kimura Ikuo、Nakano Taiji、Yamaide Fumiya、Shimojo Naoki、Ohno Hiroshi
- Journal Title
  
  Gut Microbes
  
  Volume: 15 Issue: 1
- DOI
  10.1080/19490976.2023.2206507
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22H00452
[Journal Article] Fatty acid overproduction by gut commensal microbiota exacerbates obesity2023
- Author(s)
  Takeuchi Tadashi、Kameyama Keishi、Miyauchi Eiji、Nakanishi Yumiko、Kanaya Takashi、Fujii Takayoshi、Kato Tamotsu、Sasaki Takaharu、Tachibana Naoko、Negishi Hiroki、Matsui Misato、Ohno Hiroshi
- Journal Title
  
  Cell Metabolism
  
  Volume: 35 Issue: 2 Pages: 361-375.e9
- DOI
  10.1016/j.cmet.2022.12.013
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K05907, KAKENHI-PROJECT-22H00452
[Journal Article] Gut microbial carbohydrate metabolism contributes to insulin resistance2023
- Author(s)
  Takeuchi Tadashi、Kubota Tetsuya、Nakanishi Yumiko、Tsugawa Hiroshi、Suda Wataru、Kwon Andrew Tae-Jun、Yazaki Junshi、Ikeda Kazutaka、Nemoto Shino、Mochizuki Yoshiki、Kitami Toshimori、Yugi Katsuyuki、Mizuno Yoshiko、Yamamichi Nobutake、Yamazaki Tsutomu、Takamoto Iseki、Kubota Naoto、Kadowaki Takashi、
- Journal Title
  
  Nature
  
  Volume: 621 Issue: 7978 Pages: 389-395
- DOI
  10.1038/s41586-023-06466-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08640, KAKENHI-PROJECT-21H03178, KAKENHI-PROJECT-22H00452
[Journal Article] High-throughput identification and quantification of single bacterial cells in the microbiota2022
- Author(s)
  Jin, J., Yamamoto, R., Takeuchi, T., Cui, G., Miyauchi, E., Hojo, N., Ikuta, K., Ohno, H., and Shiroguchi, K.
- Journal Title
  
  Nat. Commun.
  
  Volume: 13 Issue: 1 Pages: 863-863
- DOI
  10.1038/s41467-022-28426-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21525, KAKENHI-PLANNED-18H05411, KAKENHI-PROJECT-19H01030, KAKENHI-PROJECT-19K05907, KAKENHI-PROJECT-20H03501
[Journal Article] Acetate differentially regulates IgA reactivity to commensal bacteria2021
- Author(s)
  Takeuchi Tadashi、Miyauchi Eiji、Kanaya Takashi、Kato Tamotsu、Nakanishi Yumiko、Watanabe Takashi、Kitami Toshimori、Taida Takashi、Sasaki Takaharu、Negishi Hiroki、Shimamoto Shu、Matsuyama Akinobu、Kimura Ikuo、Williams Ifor R.、Ohara Osamu、Ohno Hiroshi
- Journal Title
  
  Nature
  
  Volume: 595 Issue: 7868 Pages: 560-564
- DOI
  10.1038/s41586-021-03727-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H01030, KAKENHI-PROJECT-21H04862, KAKENHI-PROJECT-19K05907
[Journal Article] Constructing a gnotobiotic mouse model with a synthetic human gut microbiome to study host?microbe cross talk2021
- Author(s)
  Steimle Alex、De Sciscio Alessandro、Neumann Mareike、Grant Erica T.、Pereira Gabriel V.、Ohno Hiroshi、Martens Eric C.、Desai Mahesh S.
- Journal Title
  
  STAR Protocols
  
  Volume: 2 Issue: 2 Pages: 100607-100607
- DOI
  10.1016/j.xpro.2021.100607
- Data Source
  KAKENHI-PROJECT-19H01030
[Journal Article] Bacterial cancer therapy in autochthonous colorectal cancer affects tumor growth and metabolic landscape2021
- Author(s)
  Mackie Gillian M.、Copland Alastair、Takahashi Masumi、Nakanishi Yumiko、Everard Isabel、Kato Tamotsu、Oda Hirotsugu、Kanaya Takashi、Ohno Hiroshi、Maslowski Kendle M.
- Journal Title
  
  JCI Insight
  
  Volume: 6 Issue: 23
- DOI
  10.1172/jci.insight.139900
- Data Source
  KAKENHI-PROJECT-19H01030
[Journal Article] Gut microorganisms act together to exacerbate inflammation in spinal cords2020
- Author(s)
  Miyauchi Eiji、Kim Seok-Won、Suda Wataru、Kawasumi Masami、Onawa Satoshi、Taguchi-Atarashi Naoko、Morita Hidetoshi、Taylor Todd D.、Hattori Masahira、Ohno Hiroshi
- Journal Title
  
  Nature
  
  Volume: 585 Issue: 7823 Pages: 102-106
- DOI
  10.1038/s41586-020-2634-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K05907, KAKENHI-PROJECT-19H01030
[Journal Article] CD8+ regulatory T cells are critical in prevention of autoimmune-mediated diabetes2020
- Author(s)
  3.Shimokawa C, Kato T, Takeuchi T, Ohshima N, Furuki T, Ohtsu Y, Suzue K, Imai T, Obi S, Olia A, Izumi T, Sakurai M, Arakawa H, Ohno H, Hisaeda H
- Journal Title
  
  Nature Communications
  
  Volume: 11 Issue: 1 Pages: 1922-1922
- DOI
  10.1038/s41467-020-15857-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07530, KAKENHI-PROJECT-19K16682, KAKENHI-PROJECT-19H01030
[Journal Article] Sox8 is essential for M cell maturation to accelerate IgA response at the early stage after weaning in mice2019
- Author(s)
  Kimura Shunsuke、Kobayashi Nobuhide、Nakamura Yutaka、Kanaya Takashi、Takahashi Daisuke、Fujiki Ryoji、Mutoh Mami、Obata Yuuki、Iwanaga Toshihiko、Nakagawa Tomoo、Kato Naoya、Sato Shintaro、Kaisho Tsuneyasu、Ohno Hiroshi、Hase Koji
- Journal Title
  
  The Journal of Experimental Medicine
  
  Volume: 216 Issue: 4 Pages: 831-846
- DOI
  10.1084/jem.20181604
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-17H05799, KAKENHI-PROJECT-16H05207, KAKENHI-PROJECT-17H04088, KAKENHI-PROJECT-16J09413, KAKENHI-PROJECT-16K08457, KAKENHI-PROJECT-16K08836, KAKENHI-PROJECT-17K19568, KAKENHI-PROJECT-19K22532, KAKENHI-PUBLICLY-19H04813, KAKENHI-PROJECT-19H03702
[Journal Article] Oral Administration of Porphyromonas gingivalis Alters the Gut Microbiome and Serum Metabolome2018
- Author(s)
  Kato Tamotsu、Yamazaki Kyoko、Nakajima Mayuka、Date Yasuhiro、Kikuchi Jun、Hase Koji、Ohno Hiroshi、Yamazaki Kazuhisa
- Journal Title
  
  mSphere
  
  Volume: 3 Issue: 5 Pages: 1-11
- DOI
  10.1128/msphere.00460-18
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H04067, KAKENHI-PROJECT-17H04089, KAKENHI-PROJECT-18J40011, KAKENHI-PUBLICLY-18H04680, KAKENHI-PROJECT-17KT0055
[Journal Article] Development of intestinal M cells and follicle-associated epithelium is regulated by TRAF6-mediated NF-κB signaling.2018
- Author(s)
  Kanaya T, Sakakibara S, Jinnohara T, Hachisuka M, Tachibana N, Hidano S, Kobayashi T, Kimura S, Iwanaga T, Nakagawa T, Katsuno T, Kato N, Akiyama T, Sato T, Williams IR, Ohno H.
- Journal Title
  
  J Exp Med.
  
  Volume: 5;215(2) Issue: 2 Pages: 501-519
- DOI
  10.1084/jem.20160659
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15680, KAKENHI-PUBLICLY-16H01631, KAKENHI-PLANNED-26115007, KAKENHI-PROJECT-17H06176, KAKENHI-PROJECT-16H05207, KAKENHI-PROJECT-17K08889, KAKENHI-PROJECT-17H04649, KAKENHI-PROJECT-16K08457, KAKENHI-PUBLICLY-18H04989, KAKENHI-PROJECT-17H04038
[Journal Article] An ENU-induced splice site mutation of mouse Col1a1 causing recessive osteogenesis imperfecta and revealing a novel splicing rescue.2017
- Author(s)
  Tabeta K, Du X, Arimatsu K, Yokoji M, Takahashi N, Amizuka N, Hasegawa T, Crozat K, Maekawa T, Miyauchi S, Matsuda Y, Ida T, Kaku M, Hoebe K, Ohno K, Yoshie H, Yamazaki K, Moresco EMY, Beutler B
- Journal Title
  
  Sci. Rep.
  
  Volume: 7(1) Issue: 1 Pages: 11717-11717
- DOI
  10.1038/s41598-017-10343-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11827, KAKENHI-PROJECT-15K15704, KAKENHI-PROJECT-17K19747, KAKENHI-PROJECT-15KK0337, KAKENHI-PROJECT-26293407, KAKENHI-PROJECT-15H02578, KAKENHI-PROJECT-15H04840, KAKENHI-PROJECT-16H06272, KAKENHI-PROJECT-17H06701
[Journal Article] IL-22BP dictates characteristics of Peyer's patch follicle-associated epithelium for antigen uptake.2017
- Author(s)
  Jinnohara T, Kanaya T, Hase K, Sakakibara S, Kato T, Tachibana N, Sasaki T, Hashimoto Y, Sato T, Watarai H, Kunisawa J, Shibata N, Williams I, Kiyono H, and Ohno H.
- Journal Title
  
  J. Exp. Med.
  
  Volume: 214 Issue: 6 Pages: 1607-1618
- DOI
  10.1084/jem.20160770
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17KT0055, KAKENHI-PLANNED-26115007, KAKENHI-PROJECT-17H01559, KAKENHI-PROJECT-16H05207, KAKENHI-PROJECT-17H04089, KAKENHI-PROJECT-16K14591, KAKENHI-PUBLICLY-16H01369
[Journal Article] NALT M cells are important for immune induction for the common mucosal immune system.2017
- Author(s)
  Date Y, Ebisawa M, Fukuda S, Shima H, Obata Y, Takahashi D, Kato T, Hanazato M, Nakato G, Williams IR, Hase K, Ohno H.
- Journal Title
  
  Int. Immunol.
  
  Volume: 29 Issue: 10 Pages: 471-478
- DOI
  10.1093/intimm/dxx064
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17KT0055, KAKENHI-PROJECT-16H05207, KAKENHI-PUBLICLY-16H01369
[Journal Article] Uromodulin-SlpA binding dictates Lactobacillus acidophilus uptake by intestinal epithelial M cells.2017
- Author(s)
  Yanagihara S, Kanaya T, Fukuda S, Nakato G, Hanazato M, Wu XR, Yamamoto N, Ohno H.
- Journal Title
  
  Int. Immunol.
  
  Volume: 29 Issue: 8 Pages: 357-363
- DOI
  10.1093/intimm/dxx043
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05207
[Journal Article] Maternal High Fiber Diet during Pregnancy and Lactation Influences Regulatory T Cell Differentiation in Offspring in Mice2017
- Author(s)
  Nakajima, A. Kaga, N. Nakanishi, Y. Ohno, H. Miyamoto, J. Kimura, I. Hori, S. Sasaki, T. Hiramatsu, K. Okumura, K. Miyake, S. Habu, S. Watanabe, S.
- Journal Title
  
  J Immunol
  
  Volume: 199 Issue: 10 Pages: 3516-3524
- DOI
  10.4049/jimmunol.1700248
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-17H05789, KAKENHI-PROJECT-15H04747, KAKENHI-PROJECT-17H04218, KAKENHI-PROJECT-15H05344, KAKENHI-PROJECT-15K08533
[Journal Article] Aggravation of collagen-induced arthritis by orally administered Porphyromonas gingivalis through modulation of the gut microbiota and gut immune system.2017
- Author(s)
  Sato K, Takahashi N, Kato T, Matsuda Y, Yokoji M, Yamada M, Nakajima T, Kondo N, Endo N, Yamamoto R, Noiri Y, Ohno H, Yamazaki K
- Journal Title
  
  Sci. Rep.
  
  Volume: 7(1) Issue: 1 Pages: 6955-6955
- DOI
  10.1038/s41598-017-07196-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11827, KAKENHI-PROJECT-15H02578, KAKENHI-PROJECT-15H05021, KAKENHI-PROJECT-16H05554, KAKENHI-PROJECT-17H06701
[Journal Article] High-affinity monoclonal IgA regulates gut microbiota and prevents colitis in mice.2016
- Author(s)
  Okai S, Usui F, Yokota S, Hori-I Y, Hasegawa M, Nakamura T, Kurosawa M, Okada S, Yamamoto K, Nishiyama E, Mori H, Yamada T, Kurokawa K, Matsumoto S, Nanno M, Naito T, Watanabe Y, Kato T, Miyauchi E, Ohno H, Shinkura R.
- Journal Title
  
  Nature Microbiology
  
  Volume: 1 Issue: 9 Pages: 16103-16103
- DOI
  10.1038/nmicrobiol.2016.103
- NAID
  120005818448
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-25112006, KAKENHI-PLANNED-26106004, KAKENHI-PROJECT-15H04732, KAKENHI-PROJECT-16H05207, KAKENHI-PROJECT-16J11295, KAKENHI-PROJECT-16K18711, KAKENHI-ORGANIZER-25112001
[Journal Article] Distinct Roles for the N- and C-terminal Regions of M-Sec in Plasma Membrane Deformation during Tunneling Nanotube Formation.2016
- Author(s)
  Kimura S, Yamashita M, Yamakami-Kimura M, Sato Y, Yamagata A, Kobashigawa Y, Inagaki F, Amada T, Hase K, Iwanaga T, Ohno H, Fukai S.
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Issue: 1 Pages: 33548-33548
- DOI
  10.1038/srep33548
- NAID
  120005855947
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01175, KAKENHI-PROJECT-16H04749, KAKENHI-PROJECT-16H04750, KAKENHI-PROJECT-16H05207, KAKENHI-PROJECT-24687012, KAKENHI-PROJECT-16K08457, KAKENHI-PUBLICLY-16H01369
[Journal Article] Ligature-induced periodontitis in mice induces elevated levels of circulating IL-6 but shows only weak effects on adipose and liver tissues.2016
- Author(s)
  3.Matsuda Y, Kato T, Takahashi N, Nakajima M, Arimatsu K, Minagawa T, Sato K, Ohno H, Yamazaki K.
- Journal Title
  
  Journal of Periodontal Research
  
  Volume: 51 Issue: 5 Pages: 639-646
- DOI
  10.1111/jre.12344
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H02578, KAKENHI-PROJECT-25463216, KAKENHI-PROJECT-26861808, KAKENHI-PROJECT-16K11827
[Journal Article] Epithelium-Intrinsic MicroRNAs Contribute to Mucosal Immune Homeostasis by Promoting M-Cell Maturation.2016
- Author(s)
  Nakato G, Hase K, Sato T, Kimura S, Sakakibara S, Sugiyama M, Obata Y,Hanazato M, Iwanaga T, Ohno H.
- Journal Title
  
  PLoS One
  
  Volume: 11 Issue: 3 Pages: e0150379-e0150379
- DOI
  10.1371/journal.pone.0150379
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-26116709, KAKENHI-PROJECT-15J09641, KAKENHI-PROJECT-25460261, KAKENHI-PROJECT-25293114, KAKENHI-PROJECT-16H05207
[Journal Article] Oral Administration of P. gingivalis Induces Dysbiosis of Gut Microbiota and Impaired Barrier Function Leading to Dissemination of Enterobacteria to the Liver.2015
- Author(s)
  4.Nakajima M, Arimatsu K, Kato T, Matsuda Y, Minagawa T, Takahashi N, Ohno H, Yamazaki K.
- Journal Title
  
  PLoS ONE
  
  Volume: 10 Issue: 7 Pages: 1-15
- DOI
  10.1371/journal.pone.0134234
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H02578, KAKENHI-PROJECT-13J04959
[Journal Article] Visualization of the entire differentiation process of murine M cells : suppression of their maturation in cecal patches.2015
- Author(s)
  Shunsuke Kimura, Megumi Yamakami-Kimura, Yuuki Obata, Koji Hase, Hiroshi Kitamura, Hiroshi Ohno and Toshihiko Iwanaga.
- Journal Title
  
  Mucosal Immunol.
  
  Volume: 8 Issue: 3 Pages: 650-660
- DOI
  10.1038/mi.2014.99
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13J02667, KAKENHI-PROJECT-24249029, KAKENHI-PROJECT-25293114, KAKENHI-PUBLICLY-26116709, KAKENHI-PROJECT-25460261
[Journal Article] Botulinum toxin A complex exploits intestinalM cells to enter the host and exert neurotoxicity.2015
- Author(s)
  Matsumura, T., Sugawara, Y., Yutani, M., Amatsu, S., Yagita, H., Kohda, T., Fukuoka, S.-I., Nakamura, Y., Fukuda, S., Hase, K., Ohno, H., Fujinaga, Y.
- Journal Title
  
  Nat. Commun.
  
  Volume: 6 Issue: 1 Pages: 6255-6255
- DOI
  10.1038/ncomms7255
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24249029, KAKENHI-PUBLICLY-26117725
[Journal Article] CHCHD2 mutations in autosomal dominant late-onset Parkinson’s disease: a genome-wide linkage and sequencing study.2015
- Author(s)
  Funayama M, Ohe K, Amo T, Furuya N, Yamaguchi J, Saiki S, Yuanzhe L, Ogaki K, Ando M, Yoshinon H, Tomiyama H, Nishioka K, Hasegawa K, Saiki H, Satake W, Mogushi K, Sasaki R, Kokubo Y, Kuzuhara S, Toda T, Mizuno Y, Uchiyama Y, Ohno K, Hattori N.
- Journal Title
  
  Lancet Neurol
  
  Volume: 14 Issue: 3 Pages: 274-282
- DOI
  10.1016/s1474-4422(14)70266-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22129006, KAKENHI-PROJECT-24390224, KAKENHI-PROJECT-24500868, KAKENHI-PROJECT-24790903, KAKENHI-PUBLICLY-25110720, KAKENHI-ORGANIZER-25111001, KAKENHI-PLANNED-25111007, KAKENHI-PUBLICLY-25129707, KAKENHI-PROJECT-25461291, KAKENHI-PROJECT-25461292, KAKENHI-PROJECT-25670420, KAKENHI-PROJECT-25713015, KAKENHI-PROJECT-25860725, KAKENHI-PROJECT-25860726, KAKENHI-PROJECT-26253057, KAKENHI-PROJECT-26870175, KAKENHI-PROJECT-15K10050, KAKENHI-ORGANIZER-23111001, KAKENHI-PLANNED-23111003, KAKENHI-PLANNED-23111004, KAKENHI-PROJECT-25257507, KAKENHI-PROJECT-15H04842, KAKENHI-PROJECT-25305030
[Journal Article] A novel mucosal vaccine targeting Peyer's patch M cells induces protective antigen-specific IgA responses2014
- Author(s)
  Shima, H., Watanabe, T., Fukuda, S., Fukuoka, S. I., Ohara, O., Ohno, H
- Journal Title
  
  Int. Imunol.
  
  Volume: 26 Issue: 11 Pages: 619-625
- DOI
  10.1093/intimm/dxu061
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24249029
[Journal Article] Epithelial-stromal interaction via Notch signaling is essential for the full maturation of gut-associated lymphoid tissues2014
- Author(s)
  Yuuki Obata, Shunsuke Kimura, Gaku Nakato, Keito Iizuka, Yurika Miyagawa, Yutaka Nakamura, Yukihiro Furusawa, Machiko Sugiyama, Keiichiro Suzuki, Masashi Ebisawa, Yumiko Fujimura, Hisahiro Yoshida, Toshihiko Iwanaga, Koji Hase and Hiroshi Ohno.
- Journal Title
  
  EMBO Reports
  
  Volume: 12 Issue: 12 Pages: 1297-1304
- DOI
  10.15252/embr.201438942
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13J02667, KAKENHI-PROJECT-24249029, KAKENHI-PROJECT-25293114, KAKENHI-PROJECT-25460261, KAKENHI-PUBLICLY-26116709
[Journal Article] <i>Lactobacillus acidophilus</i> L-92 Cells Activate Expression of Immunomodulatory Genes in THP-1 Cells2014
- Author(s)
  Yanagihara, S., Goto, H., Hirota, T., Fukuda, S., Ohno, H., Yamamoto, N.
- Journal Title
  
  Bioscience of Microbiota, Food and Health
  
  Volume: 33 Issue: 4 Pages: 157-164
- DOI
  10.12938/bmfh.33.157
- NAID
  130004680094
- ISSN
  2186-3342
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24249029
[Journal Article] Selection of an Aptamer against Mouse GP2 by SELEX2014
- Author(s)
  Hanazato, M., Nakato, G., Nishikawa, F., Hase, K., Nishikawa, S., Ohno, H.
- Journal Title
  
  Cell Struct. Funct.
  
  Volume: 39 Issue: 1 Pages: 23-29
- DOI
  10.1247/csf.13019
- NAID
  130004053898
- ISSN
  0386-7196, 1347-3700
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24249029
[Journal Article] AP-1B-mediated protein sorting regulates polarity and proliferation of intestinal epithelial cells in mice.2013
- Author(s)
  Hase, K., Nakatsu, F., Ohmae, M., Sugihara, K., Shioda, N., Takahashi, D., Obata, Y., Furusawa, Y., Fujimura, Y., Yamashita, T., Fukuda, S., Okamoto, H., Asano, M., Yonemura, S., Ohno, H.
- Journal Title
  
  Gastroenterol.
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20113003
[Journal Article] Distinct Roles for CXCR6+ and CXCR6- CD4+ T Cells in the Pathogenesis of Chronic Colitis2013
- Author(s)
  Mandai Y, Takahashi D, Hase K, Obata Y, Furusawa Y, Ebisawa M, Nakagawa T, Sato T, Katsuno T, Saito Y, Shimaoka T, Yokosuka O, Yokote K, Ohno H
- Journal Title
  
  PloS One
  
  Volume: 8(6) Issue: 6 Pages: e65488-e65488
- DOI
  10.1371/journal.pone.0065488
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390185, KAKENHI-PROJECT-24249029, KAKENHI-PROJECT-24659346, KAKENHI-PROJECT-24790374
[Journal Article] Treg induction by a rationally selected mixture of Clostridia strains from the human microbiota2013
- Author(s)
  Koji Atarashi, Takeshi Tanoue, et al.
- Journal Title
  
  Nature
  
  Volume: 500 Issue: 7461 Pages: 232-236
- DOI
  10.1038/nature12331
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13J04058, KAKENHI-PLANNED-22114007, KAKENHI-PROJECT-23300354, KAKENHI-PUBLICLY-24117723, KAKENHI-PROJECT-24249029, KAKENHI-PROJECT-24380072, KAKENHI-PROJECT-25293114, KAKENHI-PROJECT-25460491, KAKENHI-PROJECT-221S0002
[Journal Article] Commensal microbe-derived butyrate induces colonic regulatory T cells2013
- Author(s)
  Yukihiro Furusawa, Yuuki Obata, Shinji Fukuda, Takaho A. Endo, Gaku Nakato, Daisuke Takahashi, Yumiko Nakanishi, Chikako Uetake, Keiko Kato, Tamotsu Kato, Masumi Takahashi, Noriko N. Fukuda, Shinnosuke Murakami, Eiji Miyauchi, Shingo Hino, Koji Atarashi, Satoshi Onawa, Yumiko Fujimura, Trevor Lockett, Julie M. Clarke, David L. Topping, Masaru Tomita, Shohei Hori, Osamu Ohara, Tatsuya Morita, Haruhiko Koseki, J un Kikuchi, Kenya Honda, Koji Hase and Hiroshi Ohno
- Journal Title
  
  Nature
  
  Volume: 506 Issue: 7480 Pages: 446-450
- DOI
  10.1038/nature12721
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13J02667, KAKENHI-PROJECT-13J05482, KAKENHI-PROJECT-23780131, KAKENHI-PUBLICLY-24117524, KAKENHI-PUBLICLY-24117723, KAKENHI-PROJECT-24249029, KAKENHI-PROJECT-24380072, KAKENHI-PUBLICLY-25118733, KAKENHI-PROJECT-25293114, KAKENHI-PROJECT-25513012, KAKENHI-PROJECT-25660101, KAKENHI-PROJECT-23390123
[Journal Article] The functional maturation of M cells is dramatically reduced in the Peyer's patches of aged mice.2013
- Author(s)
  Kobayashi, A., Donaldson, D. S., Erridge, C., Kanaya, T., Williams, I. R., Ohno, H., Mahajan, A., Mabbott, N. A.
- Journal Title
  
  Mucosal Immunol.
  
  Volume: 6 Issue: 4 Pages: 1027-1037
- DOI
  10.1038/mi.2013.30
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24249029
[Journal Article] AP1B plays an important role in intestinal tumorigenesis with the truncating mutation of an APC gene.2012
- Author(s)
  Mimura, M., Masuda, A., Nishiumi, S., Kawakami, K., Fujishima, Y., Yoshie, T., Mizuno, S., Miki, I., Ohno, H., Hase, K., Minamoto, T., Azuma, T., Yoshida, M.
- Journal Title
  
  Int. J. Cancer
  
  Volume: 130 Pages: 1011-1020
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20113003
[Journal Article] Critical role of the IgM Fc receptor in IgM homeostasis, B-cell survival, and humoral immune responses.2012
- Author(s)
  Ouchida, R., Mori, H., Hase, K., Takatsu, H., Kurosaki, T., Tokuhisa, T., Ohno, H., Wang, J. Y.
- Journal Title
  
  Proc Natl Acad Sci U S A.
  
  Volume: 109
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20113003
[Journal Article] Altered Ig levels and antibody responses in mice deficient for the Fc receptor for IgM (Fc□R).2012
- Author(s)
  Honjo, K., Kubagawa, Y., Jones, D. M., Dizon, B., Zhu, Z., Ohno, H., Izui, S., Kearney, J. F., Kubagawa, H.
- Journal Title
  
  Proc Natl Acad Sci U S A.
  
  Volume: 109 Pages: 15882-15887
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20113003
[Journal Article] AP1B plays an important role in intestinal tumorigenesis with the truncating mutation of an APC gene2011
- Author(s)
  Mimura, M., et al
- Journal Title
  
  Int.J.Cancer
  
  Volume: 130 Issue: 5 Pages: 1011-1020
- DOI
  10.1002/ijc.26131
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20113003, KAKENHI-PROJECT-22249051, KAKENHI-PROJECT-23390321, KAKENHI-PROJECT-23659643
[Journal Article] SP600125 inhibits cap-dependent translation independently of the c-Jun N-terminal kinase pathway2011
- Author(s)
  Itoh M, Ohno H, et al.
- Journal Title
  
  Cell Structure and Function
  
  Volume: (印刷中)
- NAID
  130004137561
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249051
[Journal Article] Application of a mouse ligated Peyer's patch intestinal loop assay to evaluate bacterial uptake by M cells2011
- Author(s)
  Fukuda S, Hase K, Ohno H.
- Journal Title
  
  J Vis Exp
  
  Volume: 17 Pages: 3225-3225
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390155
[Journal Article] Bifidobacteria can protect from enteropathogenic infection through production of acetate.2011
- Author(s)
  Fukuda, S., Toh, H., Hase, K., Oshima, K., Nakanishi, Y., Yoshimura, K., Tobe, T., Clarke, J. M., Topping, D. L., Suzuki, T., Taylor, T. D., Itoh, K., Kikuchi, J., Morita, H., Hattori, M., Ohno, H.
- Journal Title
  
  Nature 469
  
  Pages: 543-547
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20113003
[Journal Article] Bifidobacteria can protect from enteropathogenic infection through production of acetate2011
- Author(s)
  Fukuda, S., Toh, H., Hase, K., Oshima, K., Nakanishi, Y., Yoshimura, K., Tobe, T., Clarke, J. M., Topping, D. L., Suzuki, T., Taylor, T. D., Itoh, K., Kikuchi, J., Morita, H., Hattori, M., Ohno, H.
- Journal Title
  
  Nature
  
  Volume: 469 Pages: 543-547
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390155
[Journal Article] CCR6hiCD11cint B cells promote M-cell differentiation in Peyer's patch2011
- Author(s)
  Ebisawa, M., Hase, K., Takahashi, D., Kitamura, H., Knoop, K. A., Williams, I. R., Ohno, H.
- Journal Title
  
  Int. Immunol
  
  Volume: 23 Pages: 261-269
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390155
[Journal Article] The epithelia-specific membrane trafficking factor AP-1B controls gut immune homeostasis in mice.2011
- Author(s)
  Takahashi, D., Hase, K., Kimura, S., Nakatsu, F., Ohmae, M., Mandai, Y., Sato, T., Date, Y., Ebisawa, M., Kato, T., Obata, Y., Fukuda, S., Kawamura, Y., Dohi, T., Katsuno, T., Tokosuka, O., Waguri, S., Ohno, H.
- Journal Title
  
  Gatroenterol.
  
  Volume: 141 Pages: 621-632
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20113003
[Journal Article] Dynamic omics approach identifies nutrition-mediated microbial interactions2011
- Author(s)
  Nakanishi Y, Ohno H, et al.
- Journal Title
  
  Journal of Proteome Research
  
  Volume: (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249051
[Journal Article] Identification of TOSO/FAIM3 as an Fc receptor for IgM2010
- Author(s)
  Shima, H., Takatsu, H., Fukuda, S., Ohmae, M., Hase, K., Kubagawa, H., Wang, J.-Y., Ohno, H.
- Journal Title
  
  Int. Immunol
  
  Volume: 22 Pages: 149-156
- NAID
  10027391592
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390155
[Journal Article] Identification of TOSO/FAIM3 as an Fc receptor for IgM.2010
- Author(s)
  Shima, H., Takatsu, H., Fukuda, S., Ohmae, M., Hase, K., Kubagawa, H., Wang, J.-Y., Ohno, H.
- Journal Title
  
  Int. Immunol.
  
  Volume: 22 Pages: 149-156
- NAID
  10027391592
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20113003
[Journal Article] New monitoring approach for metabolic dynamics in microbial ecosystems using stable-isotope-labeling technologies2010
- Author(s)
  Date Y, Ohno H, et al.
- Journal Title
  
  Journal of Bioscience and Bioengineering
  
  Volume: 110 Pages: 87-93
- NAID
  110007681450
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249051
[Journal Article] Bifidobacteria can protect from enteropathogenic infection through production of acetate2010
- Author(s)
  Fukuda S, et al, Ohno H
- Journal Title
  
  Nature
  
  Volume: 469 Pages: 543-547
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249051
[Journal Article] Uptake through Glycoprotein 2 of FimH+ bacteria by M cells initiates mucosal immune response.2009
- Author(s)
  Hase, K., Kawano, K., Nochi, T., Pontes, G. S., Fukuda, S., Ebisawa, M., Kadokura, K., Tobe, T., Fujimura, Y., Kawano, S., Nakato, G., Kimura, S., Murakami, T., Iimura, M., Hamura, K., Fukuoka, S. I., Lowe, A. W., Waguri, S., Itoh, K, Kiyono, H., Ohno, H.
- Journal Title
  
  Nature
  
  Volume: 462 Pages: 226-230
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20113003
[Journal Article] Uptake through Glycoprotein 2 of FimH^+bacteria by M cells initiates mucosal immune response2009
- Author(s)
  Hase, K., Kawano, K., Nochi, T., Pontes, G. S., Fukuda, S., Ebisawa, M., Kadokura, K., Tobe, T., Fujimura, Y., Kawano, S., Nakato, G., Kimura, S., Murakami, T., Iimura, M., Hamura, K., Fukuoka, S. I., Lowe, A. W., Waguri, S., Itoh, K, Kiyono, H., Ohno, H.
- Journal Title
  
  Nature
  
  Volume: 462 Pages: 226-230
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390155
[Journal Article] M-Sec promotes membrane nanotube formation by interacting with Ral and the exocyst complex.2009
- Author(s)
  Hase, K., Kimura, S., Takatsu, H., Ohmae, M., Kawano, S., Kitamura, H., Ito, M., Watarai, H., Hazelet, C. C., Yeaman, C., Ohno, H.
- Journal Title
  
  Nature Cell Biol.
  
  Volume: 11 Pages: 1427-1432
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20113003
[Journal Article] M-Sec promotes membrane nanotube formation by interacting with Ral and the exocyst complex2009
- Author(s)
  Hase, K., Kimura, S., Takatsu, H., Ohmae, M., Kawano, S., Kitamura, H., Ito, M., Watarai, H., Hazelet, C. C., Yeaman, C., Ohno, H.
- Journal Title
  
  Nature Cell Biol
  
  Volume: 11 Pages: 1427-1432
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390155
[Journal Article] Uptake via Glycoprotein 2 of FimH+ bacteria by M cells initiates mucosal immune response2009
- Author(s)
  Hase K, Kawano K, Nochi T, Pontes GS, Fukuda S, Ebisawa M, Kadokura K, Tobe T, Fujimura Y, Kawano S, Nakato G, Kimura S, Murakami T, Iimura M, Hamura K, Fukuoka SI, Lowe AW, Waguri S, Itoh K, Kiyono H, Ohno H
- Journal Title
  
  Nature 462
  
  Pages: 226-230
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-20113001
[Journal Article] M-Sec promotes membrane nanotube formation by interacting with Ral and the exocyst complex2009
- Author(s)
  Hase, K., Kimura, S., Takatsu, H., Ohmae, M., Kawano, S., Kitamura, H., Ito, M., Watarai, H., Hazelet, C. C., Yeaman, C., Ohno, H.
- Journal Title
  
  Nature Cell Biol 11
  
  Pages: 1427-1432
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20113003
[Journal Article] Uptake through Glycoprotein 2 of FimH+ bacteria by M cells initiates mucosal immune response2009
- Author(s)
  Hase, K., Kawano, K., Nochi, T., Pontes, G. S., Fukuda, S., Ebisawa, M., Kadokura, K., Tobe, T., Fujimura, Y., Kawano, S., Nakato, G., Kimura, S., Murakami, T., Iimura, M., Hamura, K., Fukuoka, S. I., Lowe, A. W., Waguri, S., Itoh, K, Kiyono, H., Ohno, H.
- Journal Title
  
  Nature 462
  
  Pages: 226-230
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20113003
[Journal Article] New approach for M-cell-specific molecules screening by comprehensive transcriptome analysis2009
- Author(s)
  Nakato, G., Fukuda, S., Hase, K., Goitsuka, R., Cooper, M. D., Ohno, H.
- Journal Title
  
  DNA Res
  
  Volume: 16(4) Pages: 227-235
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390155
[Journal Article] M-Sec promotes membrane nanotube formation by interacting with Ral and the exocyst complex2009
- Author(s)
  Hase K, Kimura S, Takatsu H, Ohmae M, Kawano S, Kitamura H, Ito M, Watarai H, Hazelet CC, Yeaman C, Ohno H
- Journal Title
  
  Nat Cell Biol 11
  
  Pages: 1427-1432
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-20113001
[Journal Article] Activation-induced cytidine deaminase deficiency causes organ-specific autoimmune disease2008
- Author(s)
  Hase, K., Takahashi, D., Ebisawa, M., Kawano, S., Itoh, K., Ohno, H.
- Journal Title
  
  PLoS ONE 3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390143
[Journal Article] Comprehensive gene expression profiling of Peyer's patch M cells, villous M-like cells, and intestinal epithelial cells2008
- Author(s)
  Terahara, K., Yoshida, M., Igarashi, O., Nochi, T., Pontes, G. S., Hase, K., Ohno, H., Kurokawa, S., Mejima, M., Takayama, N., Yuki, Y., Lowe, A. W., Kiyono, H.
- Journal Title
  
  J. Immunol. 180
  
  Pages: 7840-7846
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390143
[Journal Article] Comparative genome analysis of Lactobacillus reuteri and Lactobacillus fermentum reveal a genomic island for reuterin and cobalamin production2008
- Author(s)
  Morita, H., Toh, H., Fukuda, S., Horikawa, H., Oshima, K., Suzuki, T., Murakami, M., Hisamatsu, S., Kato, Y., Takizawa, T., Fukuoka, H., Yoshimura, T., Itoh, K., O'Sullivan, D. J., McKay, L. L., Ohno, H., Kikuchi, J., Masaoka, T., Hattori, M.
- Journal Title
  
  DNA Res 15
  
  Pages: 151-161
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390143
[Journal Article] Comprehensive gene expression profiling of Peyer's patch M cells, villous M-like cells, and intestinal epithelial cells2008
- Author(s)
  Terahara, K., Yoshida, M., Igarashi, O., Nochi, T., Pontes, G. S., Hase, K., Ohno, H., Kurokawa, S., Mejima, M., Takayama, N., Yuki, Y., Lowe, A. W., Kiyono, H.
- Journal Title
  
  J. Immunol 180
  
  Pages: 7840-7846
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390143
[Journal Article] Rats harboring S284L Chrna4 mutation show attenuation of synaptic and extrasynaptic GABAergic transmission and exhibit the nocturnal frontal lobe epilepsy phenotype.2008
- Author(s)
  Zhu, G., Okada, M., Yoshida, S., Ieno, S., Mori, F., Takahara, T., Saito, RR., Miura, Y., Kishi, A., Tomiyama, M., Sato, A., Kojima, T., Fukuma, G., Wakabayashi, K., Hase, K., Ohno, H., Kijima, H., Takano, Y., Mitsudome, A., Kaneko, S., Hirose, S
- Journal Title
  
  J.Neurosci. 28
  
  Pages: 12465-12476
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20113003
[Journal Article] Aberrant trafficking of the high-affinity choline transporter in AP-3-deficient mice2008
- Author(s)
  Misawa, H., Fujigaya, H., Nishimura, T., Moriwaki, Y., Okuda, T., Kawashima, K., Nakata, K., Ruggiero, A. M., Blakely, R. D., Nakatsu, F., Ohno, H.
- Journal Title
  
  Eur. J. Neurosci 27
  
  Pages: 3109-3117
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390143
[Journal Article] Mechanism of NKT cell activation by intranasal coadministration of a-galactosylceramide, which can induce cross-protection against influenza2008
- Author(s)
  Kamijuku, H., Nagata, Y., Jiang, X., Ichinohe, T., Tashiro, T., Mori, K., Taniguchi, M., Hase, K., Ohno, H., Shimaoka, T., Yonehara, S., Odagiri, T., Tahiro, M., Sata, T., Hasegawa, H., Seino, K-i.
- Journal Title
  
  Mucosal Immunol 1
  
  Pages: 208-218
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390143
[Journal Article] Mechanism of NKT cell activation by intranasal coadministration of a-galactosylceramide, which can induce cross-protection against influenza2008
- Author(s)
  Kamijuku, H., Nagata, Y., Jiang, X., Ichinohe, T., Tashiro, T., Mori, K., Taniguchi, M., Hase, K., Ohno, H., Shimaoka, T., Yonehara, S., Odagiri, T., Tahiro, M., Sata, T., Hasegawa, H., Seino, K-i
- Journal Title
  
  Mucosal Immunol. 1
  
  Pages: 208-218
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390143
[Journal Article] Aberrant trafficking of the high-affinity choline transporter in AP-3-deficient mice.2008
- Author(s)
  Misawa, H., Fujigaya, H., Nishimura, T., Moriwaki, Y., Okuda, T., Kawashima, K., Nakata, K., Ruggiero, A. M., Blakely, R. D., Nakatsu, F., Ohno, H.
- Journal Title
  
  Eur.J.Neurosci. 27
  
  Pages: 3109-3117
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20113003
[Journal Article] Construction of an open-access database that integrates cross-reference information from the transcriptome anda proteome of immune cells2007
- Author(s)
  Hijikata, A., Kitamura, H., Kimura, Y., Yokoyama, R., Aiba, Y., Bao, Y., Fujita, S., Hase, K., Hori, S., Ishii, Y., Kanagawa, O., Kawamoto, H., Kawano, K., Koseki, H., Kibo, M., Kurita-Miki, A., Kurosaki, T., Masuda, K., Nakata, M., Oboki, K., Ohno, H., Okamoto, M., Okayama, Y., O-Wang, J., Saito, H., Saito, T., Sakuma, M., Sato, K., Seino, K., Setoguchi, R., Tamura, Y., Tanaka, M., Taniguchi, M., Taniuchi, I., Teng, A., Watanabe, T., Watarai, H., Yamasaki, S., Ohara, O.
- Journal Title
  
  Bioinformatics 23
  
  Pages: 2934-2941
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390143
[Journal Article] Psg18 is specifically expressed in follicle-associated epithelium2007
- Author(s)
  Kawano, K., Ebisawa, M., Hase, K., Fukuda, S., Hijikata, H., Kawano, S., Date, Y., Tsuneda, S., Itoh, K., Ohno, H.
- Journal Title
  
  Cell Struct. Funct 32
  
  Pages: 115-126
- NAID
  130004137523
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390143
[Journal Article] Splenic CD19-CD35+B220+ cells function as an inducer of the follicular dendritic cell-network formation2007
- Author(s)
  Murakami, T., Chen, X., Hase, K., Sakamoto, A., Nishigaki, C., Ohno, H.
- Journal Title
  
  Blood 110
  
  Pages: 1215-1224
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390143
[Journal Article] The membrane-bound chemokine CXCL16 expressed on follicle-associated epithelium and M cells mediates lympho-epithelial interaction in GALT.2006
- Author(s)
  Hase K., Ohno H.et al.
- Journal Title
  
  J.Immunol. 176(1)
  
  Pages: 43-51
- Data Source
  KAKENHI-PROJECT-17047048
[Journal Article] Foxl1-deficient mice exhibit aberrant epithelial cell positioning due to dysregulated EphB/EphrinB expression in the small intestine.2006
- Author(s)
  Takano-Maruyama M, Hase K, Ohno H. et al.
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol. 291
- Data Source
  KAKENHI-PROJECT-17047048
[Journal Article] Distinct gene expression profiles characterize cellular phenotypes of follicle- associated epithelium and m cells.2005
- Author(s)
  Hase K., Ohno H.et al.
- Journal Title
  
  DNA Res. 12(2)
  
  Pages: 127-137
- Data Source
  KAKENHI-PROJECT-17047048
[Journal Article] Clathrin adaptor AP-2 is essential for early embryonal development.2005
- Author(s)
  Mitsunari, T., Nakatsu, F., Shioda, N., Love, P.E., Grinberg, A., Bonifacino, J.S., Ohno, H.
- Journal Title
  
  Mol.Cell.Biol. 25(21)
  
  Pages: 9318-9323
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15370042
[Journal Article] Defective function of GABA-containing synaptic vesicles in mice lacking the AP-3B clathrin adaptor.2004
- Author(s)
  Nakatsu, F., Okada, M., Mori, F., Kumazawa, N., Iwasa, H., Zhu, G., Kasagi, Y., Kamiya, H., Harada, A., Nishimura, K., Takeuchi, A., Miyazaki, T., Watanabe, M., Yuasa, S., Manabe, T., Wakabayashi, K., Kaneko, S., Saito, T., Ohno, H.
- Journal Title
  
  Cell Biol. 167(2)
  
  Pages: 293-302
- NAID
  120004898419
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15370042
[Journal Article] Reduction of SNAP25 in acid secretion defect of Foxl1-/-gastric parietal cells.2004
- Author(s)
  Kato, Y., Fukamachi, H., Takano-Maruyama, M., Aoe, T., Murahashi, Y., Horie, S., Suzuki, Y., Saito, Y., Koseki, H., Ohno H.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 320(3)
  
  Pages: 766-772
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15370042
[Journal Article] AP1B plays an important role in intestinal tumorigenesis with the truncating mutation of an APC gene.
- Author(s)
  Mimura, M., Masuda, A., Nishiumi, S., Kawakami, K., Fujishima, Y., Yoshie, T., Mizuno, S., Miki, I., Ohno, H., Hase, K., Minamoto, T., Azuma, T., Yoshida, M.
- Journal Title
  
  Int. J. Cancer in press
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20113003
[Patent] IgA腎症の予測方法およびIgA腎症患者の選択方2009
- Inventor(s)
  長澤康行、飯尾健一郎、猪阪善隆、福田真嗣、大野博司
- Industrial Property Rights Holder
  国立大学法人大阪大学、独立行政法人理化学研究所
- Industrial Property Number
  2009-029227
- Filing Date
  2009-02-01
- Data Source
  KAKENHI-PROJECT-19390143
[Patent] 原核生物、特に、真性細菌のcDNAの簡易な調整方法2008
- Inventor(s)
  守屋繁春、加藤完、福田真嗣、大野博司、菊地淳
- Industrial Property Rights Holder
  独立行政法人理化学研究所
- Industrial Property Number
  2008-052503
- Filing Date
  2008-03-03
- Data Source
  KAKENHI-PROJECT-19390143
[Patent] 腸管M細胞マーカーとしてのGP2の使用2006
- Inventor(s)
  大野博司, 河野和也, 長谷耕二
- Industrial Property Rights Holder
  独立行政法人理化学研究所
- Filing Date
  2006-12-08
- Data Source
  KAKENHI-PROJECT-17047048
[Presentation] Obesity, type 2 diabetes and gut microbiota2024
- Author(s)
  Hiroshi Ohno
- Organizer
  Pasteur Institute New Caledonia Seminar
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22H00452
[Presentation] 肥満・糖尿病と腸内細菌叢2024
- Author(s)
  大野博司
- Organizer
  2023年度東京理科大学生命医科学研究所シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-22H00452
[Presentation] Intestinal epithelial organoid (enteroid) in the study of gut pathophysiology2024
- Author(s)
  Hiroshi Ohno
- Organizer
  RIKEN Europe Symposium 2024
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22H00452
[Presentation] 私の研究歴~T細胞研究から細胞生物学、腸管免疫・腸内細菌叢の研究へ~2024
- Author(s)
  大野博司
- Organizer
  群馬大学生体調節研究所内分泌代謝学共同利用共同研究拠点第8回若手研究者育成プログラムセミナー
- Invited
- Data Source
  KAKENHI-PROJECT-22H00452
[Presentation] Obesity, type 2 diabetes and gut microbiota2024
- Author(s)
  Hiroshi Ohno
- Organizer
  Hokkaido University School of Medicine Seminar
- Invited
- Data Source
  KAKENHI-PROJECT-22H00452
[Presentation] Gut microbiota and diseases2023
- Author(s)
  Hiroshi Ohno
- Organizer
  RIKEN IMS Symposium
- Data Source
  KAKENHI-PROJECT-22H00452
[Presentation] Host-gut microbiota interaction2023
- Author(s)
  Hiroshi Ohno
- Organizer
  RIKEN-Tsinghua International Summer Program
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22H00452
[Presentation] 腸内細菌叢研究の現状と展望：小児アレルギーを中心に2023
- Author(s)
  大野博司
- Organizer
  第47回日本小児皮膚科学会学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-22H00452
[Presentation] 腸内細菌叢が宿主の生体防御・免疫系・疾患に及ぼす影響2023
- Author(s)
  大野博司
- Organizer
  腸内細菌研究会2023 in Hirosaki
- Invited
- Data Source
  KAKENHI-PROJECT-22H00452
[Presentation] 腸内細菌叢と宿主免疫系2023
- Author(s)
  大野博司
- Organizer
  東京大学大学院農学生命科学研究科免疫体機能研究社会連携講座オープニングシンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-22H00452
[Presentation] Gut microbial biomarkers involved in regulating diabetic conditions2022
- Author(s)
  Hiroshi Ohno
- Organizer
  The 9th International Human Microbiome Consortium (IHMC) Congress 2022
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22H00452
[Presentation] Impact of Gut Microbiota in Autoimmune Diseases2021
- Author(s)
  Ohno H
- Organizer
  24th SANKEN International Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H01030
[Presentation] 腸内細菌と自己免疫疾患2020
- Author(s)
  大野博司
- Organizer
  第29回腸内フローラシンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-19H01030
[Presentation] Impact of small intestinal bacteria on the pathogenesis of experimental autoimmune encephalomyelitis, an animal model of multiple sclerosis2019
- Author(s)
  Ohno H
- Organizer
  Korean Society for Biochemistry and Molecular Biology (KSBMB) International Conference 2019
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H01030
[Presentation] Gut microbiota and autoimmune diseases2019
- Author(s)
  Ohno H
- Organizer
  17th International Congress of Immunology (IUIS2019)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H01030
[Presentation] Gut microbiota and autoimmune diseases2019
- Author(s)
  Ohno H
- Organizer
  The Korean Association of Immunologists International Meeting 2019
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H01030
[Presentation] Impact of small intestinal bacteria on the pathogenesis of experimental autoimmune encephalomyelitis, an animal model of multiple sclerosis2019
- Author(s)
  Ohno H
- Organizer
  13th INTERNATIONAL SCIENTIFIC CONFERENCE ON PROBIOTICS, PREBIOTICS, GUT MICROBIOTA AND HEALTH
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H01030
[Presentation] Characteristics of M cells and follicle-associated epithelium2017
- Author(s)
  Ohno, H., Kanaya, T.
- Organizer
  第46回日本免疫学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-16H05207
[Presentation] Periodontopathic bacteria increases the severity of collagen-induced arthritis by affecting gut microbiota.2017
- Author(s)
  Yamazaki K, Sato K, Takahashi N, Kato T, Matsuda Y, Yokoji M, Yamada M, Yamazaki K, Nakajima T, Hiroshi Ohno.
- Organizer
  PgMelbourne
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02578
[Presentation] The function of M cells in host-microbe interaction2017
- Author(s)
  Ohno, H
- Organizer
  Symposium 207 Gut Microbiome and Mucosal or Systemic Dysfunction Mechanisms, Clinical Manifenstations and Intervention
- Invited
- Data Source
  KAKENHI-PROJECT-16H05207
[Presentation] Lactobacillus acidophilus L-92株の小腸パイエル板の M細胞からの取り込みに関与する生体分子の探索2017
- Author(s)
  柳原沙恵, 金谷高史, 弘田辰彦, 山本直之, 大野博司
- Organizer
  第13回日本食品免疫学会学術大会
- Data Source
  KAKENHI-PROJECT-16H05207
[Presentation] IL-22 binding protein (IL-22BP) regulates the properties of follicleassociated epithelium (FAE) to facilitate antigen uptake into Peyer's patches2017
- Author(s)
  Kanayak T., Jinnohara, T., Hase, K., Sasaki, T., Watarai, H., Shibata, N., Kuniswa, J., Kiyono, H., Ohno, H.
- Organizer
  第46回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-16H05207
[Presentation] 腸管免疫とＭ細胞2016
- Author(s)
  大野博司
- Organizer
  第40 回日本リンパ学会総会
- Place of Presentation
  東京大学伊藤国際学術研究センター（東京都・文京区）
- Year and Date
  2016-06-24
- Invited
- Data Source
  KAKENHI-PROJECT-16H05207
[Presentation] Lactobacillus acidophilus L-92株の表層蛋白質が小腸パイエル板のM細胞からの取り込みに与える影響2016
- Author(s)
  柳原沙恵、福田真嗣、金谷高史、弘田辰彦、山本直之、大野博司
- Organizer
  日本乳酸菌学会2016年度大会
- Place of Presentation
  北里大学白金キャンパスコンベンションホール(東京都・港区）
- Year and Date
  2016-07-09
- Data Source
  KAKENHI-PROJECT-16H05207
[Presentation] Periodontopathic bacteria increases the risk of rheumatoid arthritis by affecting gut immune system.2016
- Author(s)
  Sato K, Takahashi N, Nakajima M, Kato T, Matsuda Y, Yokoji M, Yamada M, Ohno H, Yamazaki K.
- Organizer
  International Congress of Immunology 2016
- Place of Presentation
  メルボルン（オーストラリア）
- Year and Date
  2016-08-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02578
[Presentation] 歯周炎モデルマウスにおける腸内細菌叢の変動と免疫応答への影響．2015
- Author(s)
  高橋直紀、有松　圭、中島麻由佳、松田由実、佐藤圭祐、多部田康一、中島貴子，加藤　完、大野博司、山崎和久．
- Organizer
  第19回腸内細菌学会
- Place of Presentation
  北里大学（東京都・港区）
- Year and Date
  2015-06-18
- Data Source
  KAKENHI-PROJECT-15H02578
[Presentation] Differentiation and function of M cells, a unique subset of intestinal epithelial cells specialized for mucosal antigen-uptake2013
- Author(s)
  Ohno, H.
- Organizer
  The American Association of Immunologists Annual Meeting
- Place of Presentation
  Honolulu, Hawaii, USA
- Invited
- Data Source
  KAKENHI-PROJECT-24249029
[Presentation] 腸内細菌と疾患2013
- Author(s)
  大野博司
- Organizer
  第86回日本内分泌学会学術総会
- Place of Presentation
  宮城県仙台市
- Invited
- Data Source
  KAKENHI-PROJECT-24249029
[Presentation] The role of M cells in intestinal helminthic infection2013
- Author(s)
  Chikako Shimokawa, Takashi Kanaya, Tsuneyasu Kaisho, Hiroshi Ohno
- Organizer
  第42回日本免疫学会学術集会
- Place of Presentation
  千葉県千葉市
- Data Source
  KAKENHI-PROJECT-24249029
[Presentation] Differentiation and function of M cells, a unique subset of intestinal epithelial cells specialized for mucosal antigen-uptake2013
- Author(s)
  Ohno, H.
- Organizer
  16th International Congress of Mucosal Immunology
- Place of Presentation
  Vancouver, Canada
- Invited
- Data Source
  KAKENHI-PROJECT-24249029
[Presentation] Antigen delivery to the gut immune system through epithelium: M cells vs FAE?2012
- Author(s)
  Ohno, H
- Organizer
  Gordon Research Conference, Lysosomes & Endocytosis
- Place of Presentation
  Andover, NH, USA
- Invited
- Data Source
  KAKENHI-PROJECT-24249029
[Presentation] Function and differentiation of M cells, a unique subset of intestinal epithelial cells specialized for mucosal antigen-uptake2012
- Author(s)
  Ohno, H
- Organizer
  The 12th International Symposium on Dendritic Cells
- Place of Presentation
  Daegu, Korea
- Year and Date
  2012-10-07
- Invited
- Data Source
  KAKENHI-PLANNED-20113003
[Presentation] The role of M cells in intestinal immunity2012
- Author(s)
  Ohno, H
- Organizer
  International Endotoxin ＆ Innate Immunity Society Meeting 2012, Homeostatic Inflammation Symposium, Japan Endotoxin and Innate Immunity Society 2012
- Place of Presentation
  Tokyo, Japan
- Year and Date
  2012-10-23
- Invited
- Data Source
  KAKENHI-PLANNED-20113003
[Presentation] Function and differentiation of M cells, a unique subset of intestinal epithelial cells specialized for mucosal antigen-uptake.2012
- Author(s)
  Ohno, H.
- Organizer
  The 12th International Symposium on Dendritic Cells.
- Place of Presentation
  Daegu, Korea
- Year and Date
  2012-10-11
- Data Source
  KAKENHI-PLANNED-20113003
[Presentation] Role of Commensal Microbiota in Intestinal Immunity and Host Defense2012
- Author(s)
  Ohno, H.
- Organizer
  The 3rd International Forum, The 98th General Meeting of the Japanese Society of Gastroenterology
- Place of Presentation
  東京
- Year and Date
  2012-04-20
- Data Source
  KAKENHI-PROJECT-21390155
[Presentation] M cells, a unique subset of intestinal epithelial cells specialized for mucosal antigen-uptake.2012
- Author(s)
  Ohno, H.
- Organizer
  The 2012 Spring Conference of the Korean Association of Immunologists.
- Place of Presentation
  Seoul, Korea
- Year and Date
  2012-04-13
- Data Source
  KAKENHI-PLANNED-20113003
[Presentation] M cells, a unique subset of intestinal epithelial cells specialized for mucosal antigen-uptake2012
- Author(s)
  Ohno, H
- Organizer
  The 2012 Spring Conference of the Korean Association of Immunologists
- Place of Presentation
  Seoul, Korea
- Year and Date
  2012-04-12
- Invited
- Data Source
  KAKENHI-PLANNED-20113003
[Presentation] Antigen delivery to the gut immune system through epithelium: M cells vs FAE?2012
- Author(s)
  Ohno, H.
- Organizer
  Gordon Research Conference, Lysosomes & Endocytosis Andover
- Place of Presentation
  NH, USA
- Year and Date
  2012-06-21
- Data Source
  KAKENHI-PLANNED-20113003
[Presentation] M cells, a unique subset of intestinal epithelial cells specialized for mucosal antigen-uptake2012
- Author(s)
  Ohno, H
- Organizer
  M cells, a unique subset of intestinal epithelial cells specialized for mucosal antigen-uptake
- Place of Presentation
  淡路島、兵庫
- Invited
- Data Source
  KAKENHI-PROJECT-24249029
[Presentation] The role of M cells in intestinal immunity.2012
- Author(s)
  Ohno, H.
- Organizer
  International Endotoxin & Innate Immunity Society Meeting 2012, Homeostatic Inflammation Symposium, Japan Endotoxin and Innate Immunity Society 2012.
- Place of Presentation
  Tokyo, Japan
- Year and Date
  2012-10-26
- Data Source
  KAKENHI-PLANNED-20113003
[Presentation] Understanding the host-gut microbiota interaction with multi-omics approach2012
- Author(s)
  Ohno,H
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  Fukuoka, Japan
- Year and Date
  2012-12-14
- Invited
- Data Source
  KAKENHI-PLANNED-20113003
[Presentation] Antigen delivery to the gut immune system through epithelium: M cells vs FAE?2012
- Author(s)
  Ohno, H
- Organizer
  Gordon Research Conference, Lysosomes & Endocytosis
- Place of Presentation
  Andoverm NH, USA
- Year and Date
  2012-06-17
- Invited
- Data Source
  KAKENHI-PLANNED-20113003
[Presentation] Function and differentiation of M cells, a unique subset of intestinal epithelial cells specialized for mucosal antigen-uptake2012
- Author(s)
  Ohno,H
- Organizer
  The 12th International Symposium on Dendritic Cells
- Place of Presentation
  Daegu, Korea
- Invited
- Data Source
  KAKENHI-PROJECT-24249029
[Presentation] NALTにおけるM細胞を介した粘膜免疫応答2011
- Author(s)
  伊達康博、海老澤昌史、福田真嗣、尾畑祐樹、高橋大輔、嶋秀明、花里美紗穂、中藤学、常田聡、Williams, I. R.、長谷耕二、大野博司
- Organizer
  第40回日本免疫学会学術集会
- Place of Presentation
  千葉
- Year and Date
  2011-11-28
- Data Source
  KAKENHI-PROJECT-21390155
[Presentation] The role of M-Sec in tunneling nanotube formation2011
- Author(s)
  Ohno, H
- Organizer
  EMBO Meeting 2011
- Place of Presentation
  Vienna, Austria(招待講演)
- Year and Date
  2011-09-11
- Data Source
  KAKENHI-PROJECT-21390155
[Presentation] The role of M-Sec in tunneling nanotube formation2011
- Author(s)
  Ohno, H.
- Organizer
  EMBO Meeting 2011
- Place of Presentation
  Vienna, Austria(招待講演)
- Year and Date
  2011-09-11
- Data Source
  KAKENHI-PLANNED-20113003
[Presentation] Function and differentiation of M cells, a unique subset of intestinal epithelial cells important for mucosal immunity2011
- Author(s)
  Ohno, H.
- Organizer
  ComBio2011
- Place of Presentation
  Cains, australia(招待講演)
- Year and Date
  2011-09-28
- Data Source
  KAKENHI-PLANNED-20113003
[Presentation] The role of M-Sec in tunneling nanotube formation.2011
- Author(s)
  Ohno, H., Hase, K., Kimura, S., Fukai, S.
- Organizer
  EMBO Meeting 2011 Workshop 'Role of nanotubes in intercellular signaling'
- Place of Presentation
  Vienna, Austria
- Year and Date
  2011-09-10
- Data Source
  KAKENHI-PLANNED-20113003
[Presentation] 腸管関連リンパ組織形成における上皮性Notchシグナルの役割。2011
- Author(s)
  尾畑祐樹、海老澤昌史、杉山真知子、長谷耕二、大野博司
- Organizer
  第40回日本免疫学会学術集会
- Place of Presentation
  千葉
- Year and Date
  2011-11-28
- Data Source
  KAKENHI-PROJECT-21390155
[Presentation] Function and differentiation of M cells, a unique subset of intestinal epithelial cells important for mucosal immunity2011
- Author(s)
  Ohno, H
- Organizer
  ComBio2011
- Place of Presentation
  Cains, australia(招待講演)
- Year and Date
  2011-09-28
- Data Source
  KAKENHI-PROJECT-21390155
[Presentation] M Cells and Antigen Delivery to DCs in the Gut.2011
- Author(s)
  Hase, K., Kawano, K., Ebisawa, M., Ohno, H.
- Organizer
  Keystone Symposia 'Dendritic Cells and the Initiation of Adaptive Immunity (J7)'
- Place of Presentation
  Santa Fe, NM, USA
- Year and Date
  2011-02-16
- Data Source
  KAKENHI-PLANNED-20113003
[Presentation] M Cells and Antigen Delivery to DCs in the Gut2011
- Author(s)
  Hase, K., Kawano, K., Ebisawa, M., Ohno, H.
- Organizer
  Keystone Symposia 'Dendritic Cells and the Initiation of Adaptive Immunity(J7)'
- Place of Presentation
  Santa Fe, NM, USA
- Year and Date
  2011-02-16
- Data Source
  KAKENHI-PROJECT-21390155
[Presentation] Function and differentiation of M cells, a unique subset of intestinal epithelial cells important for mucosal immunity.2011
- Author(s)
  Ohno, H.
- Organizer
  ComBio2011, Plenary Lecture,
- Place of Presentation
  Cairns, Australia
- Year and Date
  2011-09-28
- Data Source
  KAKENHI-PLANNED-20113003
[Presentation] M細胞に発現するプリオンタンパク質はBrucella abortusの取り込み受容体として機能する2011
- Author(s)
  中藤学、長谷耕二、鈴木道夫、西田教行、堀内基広、阿戸学ぶ、大野博司
- Organizer
  第40回日本免疫学会学術集会
- Place of Presentation
  千葉
- Year and Date
  2011-11-29
- Data Source
  KAKENHI-PROJECT-21390155
[Presentation] M cells and Antigen Delivery to DCs in the Gut2011
- Author(s)
  Ohno H.
- Organizer
  Keystone Syposia
- Place of Presentation
  Santa Fe, NM, USA
- Year and Date
  2011-02-16
- Data Source
  KAKENHI-PLANNED-20113003
[Presentation] M cells and Antigen Delivery to DCs in the Gut2011
- Author(s)
  Ohno H.
- Organizer
  Keystone Syposia
- Place of Presentation
  Santa Fe, NM, USA
- Year and Date
  2011-02-16
- Data Source
  KAKENHI-PROJECT-21390155
[Presentation] 食物アレルギーと腸管免疫・経口免疫寛容。2011
- Author(s)
  大野博司
- Organizer
  第18回日本免疫毒性学会シンポジウム
- Place of Presentation
  千葉
- Year and Date
  2011-09-08
- Data Source
  KAKENHI-PROJECT-21390155
[Presentation] The role of M-Sec in tunneling nanotube formation. EMBO Meeting2011
- Author(s)
  Ohno, H., Hase, K., Kimura, S., Fukai, S.
- Organizer
  2011 Workshop 'Role of nanotubes in intercellular signaling'
- Place of Presentation
  Vienna, Austria
- Year and Date
  2011-09-10
- Data Source
  KAKENHI-PROJECT-21390155
[Presentation] Function and differentiation of M cells, a unique subset of intestinal epithelial cells important for mucosal immunity2011
- Author(s)
  Ohno, H.
- Organizer
  Plenary Lecture
- Place of Presentation
  Cairns, Australia
- Year and Date
  2011-09-28
- Data Source
  KAKENHI-PROJECT-21390155
[Presentation] The Fc receptor for IgM(Fc R) plays an important role in humoral immune responses to low-dose antigen2011
- Author(s)
  Ouchida, R., Mori, H., Hase, K., Kurosaki, T., Tokuhisa, T., Ohno, H., Wang, J.-Y
- Organizer
  第40回日本免疫学会学術集会
- Place of Presentation
  千葉
- Year and Date
  2011-11-28
- Data Source
  KAKENHI-PROJECT-21390155
[Presentation] M-Sec : a promoter of tunneling nanotube formation2010
- Author(s)
  Ohno, H.
- Organizer
  Biochemistry and Molecular Biology 2010
- Place of Presentation
  Kobe, Japan
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PLANNED-20113003
[Presentation] 食物アレルギーと腸管免疫・経口免疫寛容2010
- Author(s)
  大野博司
- Organizer
  第60回日本アレルギー学会秋季学術大会
- Place of Presentation
  東京
- Year and Date
  2010-11-27
- Data Source
  KAKENHI-PLANNED-20113003
[Presentation] Bacterial recognition and uptake by M cells2010
- Author(s)
  Ohno, H.
- Organizer
  The 63rd Annual Meeting of the Japan Society for Cell Biology
- Place of Presentation
  Osaka, Japan
- Year and Date
  2010-05-21
- Data Source
  KAKENHI-PLANNED-20113003
[Presentation] Glycoprotein 2 : An Antigen-Uptake Receptor on Intestinal Epithelial M Cells for Mucosal Immunity2010
- Author(s)
  Ohno, H.
- Organizer
  Traffc Symposium
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2010-06-04
- Data Source
  KAKENHI-PLANNED-20113003
[Presentation] Glycoprotein 2 : An Antigen-Uptake Receptor on Intestinal Epithelial M Cells for Mucosal Immunity2010
- Author(s)
  Ohno, H.
- Organizer
  Traffc Symposium
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2010-06-04
- Data Source
  KAKENHI-PROJECT-21390155
[Presentation] GP2-dependent antigen transcytosis by M cells intiates antigen-specific mucosal immune response2010
- Author(s)
  Hase, K., Nochi, T., Pontes, G. S., Fukuda, S., Ebisawa, M., Kadokura, K., Kiyono, H., Ohno, H.
- Organizer
  14th International Congress of Immunology(ICI 2010)
- Place of Presentation
  神戸
- Year and Date
  2010-08-26
- Data Source
  KAKENHI-PROJECT-21390155
[Presentation] Distinct miRNA expression Profiles of Follicle-associated Epithelium(FAE) and Villous Epithelium(VE)2010
- Author(s)
  Nakato, G., Hase, K., Ohno, H.
- Organizer
  19th CDB Meeting : RNA Sciences in Cell and Developmental Biology
- Place of Presentation
  神戸
- Year and Date
  2010-05-12
- Data Source
  KAKENHI-PROJECT-21390155
[Presentation] Identification of TOSO/FAIM3 as an Fc receptor for IgM2010
- Author(s)
  Shima, H., Takatsu, H., Fukuda, S., Ohmae, M., Hase, K., Kubagawa, H., Wang, J.-Y., Ohno, H.
- Organizer
  14th International Congress of Immunology(ICI 2010)
- Place of Presentation
  神戸
- Year and Date
  2010-08-25
- Data Source
  KAKENHI-PROJECT-21390155
[Presentation] 食物アレルギーと腸管免疫・経口免疫寛容2010
- Author(s)
  大野博司
- Organizer
  第60回日本アレルギー学会秋季学術大会
- Place of Presentation
  東京
- Year and Date
  2010-11-27
- Data Source
  KAKENHI-PROJECT-21390155
[Presentation] Identification of TOSO/FAIM3 as an Fc receptor for IgM.2010
- Author(s)
  Shima, H., Takatsu, H., Fukuda, S., Ohmae, M., Hase, K., Kubagawa, H., Wang, J.-Y., Ohno, H.
- Organizer
  14th International Congress of Immunology (ICI 2010)
- Place of Presentation
  神戸
- Year and Date
  2010-08-25
- Data Source
  KAKENHI-PLANNED-20113003
[Presentation] Bacterial recognition and uptake by M cells2010
- Author(s)
  Ohno, H.
- Organizer
  The 63rd Annual Meeting of the Japan Society for Cell Biology
- Place of Presentation
  Osaka, Japan
- Year and Date
  2010-05-21
- Data Source
  KAKENHI-PROJECT-21390155
[Presentation] M-Sec : a promoter of tunneling nanotube formation2010
- Author(s)
  Ohno, H.
- Organizer
  Biochemistry and Molecular Biology 2010
- Place of Presentation
  Kobe, Japan
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-21390155
[Presentation] GP2-dependent antigen transcytosis by M cells intiates antigen-specific mucosal immune response.2010
- Author(s)
  Hase, K., Nochi, T., Pontes, G. S., Fukuda, S., Ebisawa, M., Kadokura, K., Kiyono, H., Ohno, H.
- Organizer
  14th International Congress of Immunology (ICI 2010)
- Place of Presentation
  神戸
- Year and Date
  2010-08-26
- Data Source
  KAKENHI-PLANNED-20113003
[Presentation] Identification of RNA aptamers targeting mouse GP2 proteins by SELEX2009
- Author(s)
  Hanazato, M., Nakato, G., Nishikawa, F., Hase, K. Nishikawa, S., Ohno, H.
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-12-11
- Data Source
  KAKENHI-PROJECT-21390155
[Presentation] Functional analysis of CCL9 in the intestinal immune system2009
- Author(s)
  Yamazaki, R., Kimura, S., Hase, K., Ebisawa, M., Date, Y., Tsuneda, S., Suzuki, H., Ohno, H.
- Organizer
  第61回日本細胞生物学会大会
- Place of Presentation
  名古屋
- Year and Date
  2009-06-02
- Data Source
  KAKENHI-PROJECT-21390155
[Presentation] Multi-omic analysis identifies microbial metabolites to protect host from enterohaemorrhagic Escherichia coli O157:H7 lethal infection2009
- Author(s)
  Fukuda, S., Nakanishi, Y., Toh, H., Yoshimura, K., Oshima, K., Morita, H., Tobe, T., Itoh, K., Kikuchi, J., Hattori, M., Ohno, H.
- Organizer
  Keystone Symposia on Molecular and Cellular Biology "Innate, Adaptive and Regulatory Immune Responses to Intestinal Microbiota"
- Year and Date
  2009-01-14
- Data Source
  KAKENHI-PROJECT-19390143
[Presentation] CCR6^<hi> CD11c^+B cells promote M-cell differentiation in Peyer's patch2009
- Author(s)
  Ebisawa, M., Hase, K., Takahashi, D., Kitamura, H., Williams, I. R., Ohno, H.
- Organizer
  第32回日本分子生物学会年会ワークショップ
- Place of Presentation
  横浜
- Year and Date
  2009-12-09
- Data Source
  KAKENHI-PROJECT-21390155
[Presentation] Functional analysis of CCL9 in the intestinal immune system2009
- Author(s)
  Yamazaki, R., Kimura, S., Ebisawa, M., Date, Y., Tsuneda, S., Suzuki, H., Hase, K., Ohno, H.
- Organizer
  第39回日本免疫学会総会学術集会
- Place of Presentation
  大阪
- Year and Date
  2009-12-02
- Data Source
  KAKENHI-PROJECT-21390155
[Presentation] M-Secによる細胞間ナノチューブ形成促進の分子機構2009
- Author(s)
  長谷耕二、高津宏之、木村俊介、大野博司
- Organizer
  第61回日本細胞生物学会大会ワークショップ
- Place of Presentation
  名古屋
- Year and Date
  2009-06-03
- Data Source
  KAKENHI-PROJECT-21390155
[Presentation] GP2-dependent antigen transcytosis by M cells initiates antigen-specific mucosal immune response.2009
- Author(s)
  Hase, K., Nochi, T., Pontes, G. S., Fukuda, S., Ebisawa, M., Kadokura, K., Kiyono, H., Ohno, H.
- Organizer
  第39回日本免疫学会総会学術集会シンポジウム
- Place of Presentation
  大阪
- Year and Date
  2009-12-02
- Data Source
  KAKENHI-PLANNED-20113003
[Presentation] M-Sec による細胞間ナノチューブ形成促進の分子機構2009
- Author(s)
  長谷耕二、高津宏之、木村俊介、大野博司
- Organizer
  第61回日本細胞生物学会大会ワークショップ
- Place of Presentation
  名古屋
- Year and Date
  2009-06-03
- Data Source
  KAKENHI-PLANNED-20113003
[Presentation] CCR6^<hi> CD11c^+ B cells promote M-cell differentiation in Peyer's patch.2009
- Author(s)
  Ebisawa, M., Hase, K., Takahashi, D., Kitamura, H., Williams, I. R., Ohno, H.
- Organizer
  第32回日本分子生物学会年会ワークショップ
- Place of Presentation
  横浜
- Year and Date
  2009-12-09
- Data Source
  KAKENHI-PLANNED-20113003
[Presentation] Study on the process of antigen transcytosis by M cells2009
- Author(s)
  Kimura, S., Sakamoto, A., Yamazaki, R., Kawano, K., Hase, K., Ohno, H.
- Organizer
  第61回日本細胞生物学会大会
- Place of Presentation
  名古屋
- Year and Date
  2009-06-02
- Data Source
  KAKENHI-PROJECT-21390155
[Presentation] GP2-dependent antigen transcytosis by M cells initiates antigen-specific mucosal immune response2009
- Author(s)
  Hase, K., Nochi, T., Pontes, G. S., Fukuda, S., Ebisawa, M., Kadokura, K., Kiyono, H., Ohno, H.
- Organizer
  第39回日本免疫学会総会学術集会シンポジウム
- Place of Presentation
  大阪
- Year and Date
  2009-12-02
- Data Source
  KAKENHI-PROJECT-21390155
[Presentation] Glycoprotein 2, a transcytotic receptor expressed by intestinal M cells, plays a critical role in immunosurveillance against enterobacteria2009
- Author(s)
  Kawano, K., Hase, K., Nochi, T., Pontes, G. S., Fukuda, S., Nakato, G., Ebisawa, M., Iimura, M., Fukuoka, S., Waguri, S., Itoh, K., Kiyono, H., Ohno, H.
- Organizer
  Keystone Symposia on Molecular and Cellular Biology "Innate, Adaptive and Regulatory Immune Responses to Intestinal Microbiota"
- Year and Date
  2009-01-16
- Data Source
  KAKENHI-PROJECT-19390143
[Presentation] Comprehensive analysis of the expression of M-cell-associated proteins among mucosa-associated lymphoid tissue2008
- Author(s)
  Date, Y., Fukuda, S., Hase, K., Tsuneda, S., Ohno, H.
- Organizer
  第38回日本免疫学会学術集会
- Year and Date
  2008-12-03
- Data Source
  KAKENHI-PROJECT-19390143
[Presentation] Spatial and temporal specific expression patterns of RANLK/RANK in developing peripheral lymphoid organs2008
- Author(s)
  Sugiyama, M., Ohno, H., Yoshida, H.
- Organizer
  第38回日本免疫学会学術集会
- Year and Date
  2008-12-02
- Data Source
  KAKENHI-PROJECT-19390143
[Presentation] (2008) CXCR6 is upregulated in effector memory CD4+ T cells infiltrating into chronically inflamed colonic tissue2008
- Author(s)
  Mandai, Y., Hase, K., Sato, T., Takahashi, D., Ebisawa, M., Katsuno, Y., Saito, Y., Ohno, H.
- Organizer
  Digestive Disease Week-
- Year and Date
  2008-05-19
- Data Source
  KAKENHI-PROJECT-19390143
[Presentation] Deficiency of epithelium-specific basolateral sorting factor AP-1B heads to spontaneous development of colitis2008
- Author(s)
  Takahashi, D., Hase, K., Ohno, H.
- Organizer
  第38回日本免疫学会学術集会
- Year and Date
  2008-12-03
- Data Source
  KAKENHI-PROJECT-19390143
[Presentation] Comprehensive gene expression profiling of antigen-sampling M cells: Specific expression of GP2 and MLP genes by Peyer's patch M cells2008
- Author(s)
  吉田理人、寺原和孝、野地智法、Pontes, G. S., 長谷耕二、大野博司、幸義和、清野宏
- Organizer
  第38回日本免疫学会学術集会
- Year and Date
  2008-12-03
- Data Source
  KAKENHI-PROJECT-19390143
[Presentation] 腸内細菌の代謝変動に着目した植物性プレバイオティクス候補の探索2008
- Author(s)
  中西由美子、縫島裕美、福田真嗣、加藤完、梅原三貴久、大野博司、菊地淳
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
- Year and Date
  2008-12-11
- Data Source
  KAKENHI-PROJECT-19390143
[Presentation] Tunneling nanotubules formed by Peyer's patch M cells : Potential function as the antigen-transporting web2008
- Author(s)
  Hase, K., Takatsu, H., Kimura, S., Ohno, H.
- Organizer
  第38回日本免疫学会学術集会
- Place of Presentation
  京都
- Year and Date
  2008-12-03
- Data Source
  KAKENHI-PROJECT-19390143
[Presentation] リンパ濾胞上皮層における宿主-微生物相互作用の解析2008
- Author(s)
  福田真嗣、大野博司
- Organizer
  Hindgut Club Japan 2008
- Year and Date
  2008-12-06
- Data Source
  KAKENHI-PROJECT-19390143
[Presentation] Tunneling nanotubules formed by Peyer's patch M cells: Potential function as the antigen-transporting web2008
- Author(s)
  Hase, K., Takatsu, H., Kimura, S., Ohno, H.
- Organizer
  第38回日本免疫学会学術集会
- Year and Date
  2008-12-03
- Data Source
  KAKENHI-PROJECT-19390143
[Presentation] 小腸パイエル板M細胞におけるCCL9の機能解析2008
- Author(s)
  山崎龍、木村俊介、長谷耕二、伊達康博、海老澤昌史、大野博司
- Organizer
  Hindgut Club Japan 2008
- Year and Date
  2008-12-06
- Data Source
  KAKENHI-PROJECT-19390143
[Presentation] 通常培養状態におけるc-Jun N-terminal kinase (JNK)による翻訳制御2008
- Author(s)
  伊藤誠.、北村浩、菊口千智、湯浅朋子、大野博司、小原収
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
- Year and Date
  2008-12-12
- Data Source
  KAKENHI-PROJECT-19390143
[Presentation] 栄養源に伴う腸内環境変動の微生物群集構造解析法に基づく評価2008
- Author(s)
  中西由美子、福田真嗣、伊達康博、加藤完、坪井裕理、常田聡、大野博司、菊地淳
- Organizer
  日本農芸化学会2008年度大会
- Year and Date
  2008-03-27
- Data Source
  KAKENHI-PROJECT-19390143
[Presentation] Brucella abortus is taken up via intestinal M cells by interacting with cellular prion protein2008
- Author(s)
  Nakato, G., Hase, K., Fukuda, S., Kawano, K., Ohno, H.
- Organizer
  第38回日本免疫学会学術集会
- Year and Date
  2008-12-02
- Data Source
  KAKENHI-PROJECT-19390143
[Presentation] Cell polarity regulates proliferation of intestinal epithelial cells.2008
- Author(s)
  Hase, K., Nakatsu, F., Ohno, H.
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2008-12-11
- Data Source
  KAKENHI-PLANNED-20113003
[Presentation] バクテリア発現遺伝子情報を付与したDGGE-NMR相関解析法による腸内環境評価系の構築2008
- Author(s)
  加藤完、伊達康博、福田真嗣、中西由美子、近山英輔、坪井裕理、常田聡、守屋繁春、菊地淳、大野博司
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
- Year and Date
  2008-12-11
- Data Source
  KAKENHI-PROJECT-19390143
[Presentation] 腸内環境を評価するためのバクテリア発現遺伝子解析法の構築2008
- Author(s)
  加藤完、伊達康博、福田真嗣、中西由美子、近山英輔、坪井裕理、常田聡、守屋繁春、菊地淳、大野博司
- Organizer
  Hindgut Club Japan 2008
- Year and Date
  2008-12-06
- Data Source
  KAKENHI-PROJECT-19390143
[Presentation] CXCR6 is upregulated in effector CD4+ T cells infiltrating into chronically inflamed colonic tissue2008
- Author(s)
  Mandai, Y., Takahashi, D., Hase, K., Sato, T., Ebisawa, M., Katsuno, Y., Ohno, H.
- Organizer
  第38回日本免疫学会学術集会
- Year and Date
  2008-12-03
- Data Source
  KAKENHI-PROJECT-19390143
[Presentation] Glycopotein 2 is specifically expressed on the apical membrane of Peyre's patch M cells but not Villous M cells2008
- Author(s)
  Pontes, G. S., Toshida, M., Nochi, T., Hase, K., Ohno, H., Terahara, K., Yuki, Y., Koyono, H.
- Organizer
  第38回日本免疫学会学術集会
- Year and Date
  2008-12-03
- Data Source
  KAKENHI-PROJECT-19390143
[Presentation] Identification of molecules expressed in FAE and M cells to be involved inmucosal immunity2007
- Author(s)
  Ohno, H, 他
- Organizer
  第37回日本免疫学会学術集会
- Place of Presentation
  東京
- Year and Date
  2007-11-21
- Data Source
  KAKENHI-PROJECT-19390143
[Presentation] Epithelial-specific adaptor complex, AP-1B is essential for maintenance of immunological tolerance in the colon2007
- Author(s)
  Takahashi, D., Hase, K., Ohno, H.
- Organizer
  第37回日本免疫学会学術集会
- Year and Date
  2007-11-21
- Data Source
  KAKENHI-PROJECT-19390143
[Presentation] Identification of molecules expressed in FAE and M cells to be involved in mucosal immunity.2007
- Author(s)
  Ohno, H. 他
- Organizer
  第37回日本免疫学会学術集会
- Place of Presentation
  東京
- Year and Date
  2007-11-21
- Data Source
  KAKENHI-PROJECT-15079203
[Presentation] 非ストレス状態におけるJNKによる翻訳調節2007
- Author(s)
  Ito, M., Kitamura, H., Kikuguchi, C., Yuasa, T., Ohara, O., Ohno, H.
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学会大会合同大会
- Year and Date
  2007-12-13
- Data Source
  KAKENHI-PROJECT-19390143
[Presentation] Differential gene expression profiles of follicle-associated epithelium covering murine intestinal Peyer's patches in response to host-bacterial cross-talks2007
- Author(s)
  Fukuda, S., Nakato, G., Miura, K., Kawano, K., Hase, K., Itoh, K., Ohno, H.
- Organizer
  13^<th> International Congress of mucosal Immunology
- Year and Date
  2007-07-10
- Data Source
  KAKENHI-PROJECT-19390143
[Presentation] Gene expression profiles of follicle-associated epithelium covering murine intestinal Peyer's patches in response to host-bacterial cross-talk2007
- Author(s)
  Fukuda, S., Nakato, G., Miura, K., Date, Y., Yokosawa, K., Kawano, K., Hase, K., Tsuneda, S., Itoh, K., Ohno, H.
- Organizer
  第37回日本免疫学会学術集会
- Year and Date
  2007-11-21
- Data Source
  KAKENHI-PROJECT-19390143
[Presentation] Bacterial adhesin is a ligand for endocytic receptor glycoprotein 2 expressed on M cells2007
- Author(s)
  Kawano, K., Hase, K., Fukuda, S., Nakato, G., Murakami, T., Ebisawa, M., Itoh, K., Ohno, H.
- Organizer
  第37回日本免疫学会学術集会
- Year and Date
  2007-11-21
- Data Source
  KAKENHI-PROJECT-19390143
[Presentation] Identification of molecules expressed in FAE and M cells to be involved in mucosal immunity2007
- Author(s)
  Kawano, K., Hase, K., Ohno, H.
- Organizer
  第37回日本免疫学会総会・学術集会
- Year and Date
  2007-11-21
- Data Source
  KAKENHI-PROJECT-19390143
[Presentation] (2007 )腸内細菌群のニュートリメタボノミクス基盤技術の構築2007
- Author(s)
  Nakanishi, Y., Fukuda, S., Chikayama, E,. Kimura, Y., Ohno, H., Kikuchi, J.
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学会大会合同大会
- Year and Date
  2007-12-13
- Data Source
  KAKENHI-PROJECT-19390143
[Presentation] Endogenous prion protein expressed on the apical plasma membrane in M cells could function as a potential antigen uptake receptor2007
- Author(s)
  Nakato, G., Fukuda, S., Takatsu, H., Murakami, T., Kawano, K., Hase, K., Ohno, H.
- Organizer
  13^<th> International Congress of mucosal Immunology
- Year and Date
  2007-07-10
- Data Source
  KAKENHI-PROJECT-19390143
[Presentation] ニュートリメタボノミクスにおける安定同位体標識技術の適用2007
- Author(s)
  Date, Y., Nakanishi, Y., Fukuda, S., Tsuneda, S., Ohno, H., Kikuchi, J.
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学会大会合同大会
- Year and Date
  2007-12-13
- Data Source
  KAKENHI-PROJECT-19390143
[Presentation] 宿主.腸内フローラ間相互作用の解析とその評価系の構築2007
- Author(s)
  福田真嗣、中藤学、中西裕美子、三浦克吉、伊藤喜久治、菊地淳、大野博司
- Organizer
  第11回腸内細菌学会
- Year and Date
  2007-06-12
- Data Source
  KAKENHI-PROJECT-19390143
[Presentation] Identification of a CD11c^+CD19^+ unique cell population in the mucosa-associated lymphoid tissues: A potential role in M cell development2007
- Author(s)
  Ebisawa, M., Hase, K., Ohno, H.
- Organizer
  第37回日本免疫学会学術集会
- Year and Date
  2007-11-21
- Data Source
  KAKENHI-PROJECT-19390143
[Presentation] Identification of a new endocytic receptor expressed in the apical plasma membrane of M cells2007
- Author(s)
  Kawano, K., Hase, K., Fukuda, S., Murakami, T., Waguri, S., Itoh, K., Ohno, H.
- Organizer
  13^<th> International Congress of mucosal Immunology
- Year and Date
  2007-07-10
- Data Source
  KAKENHI-PROJECT-19390143
[Presentation] T CD300 antigen like family member G: A novel Ig receptor like protein exclusively expressed on capillary endothelium2007
- Author(s)
  akatsu, H., Hase, K., Ohmae, M., Ohshima, S., Yamamoto, A., Ohno, H.
- Organizer
  第40回日本発生生物学会・第59回日本細胞生物学会合同大会
- Year and Date
  2007-05-30
- Data Source
  KAKENHI-PROJECT-19390143
[Presentation] Psg18 is specifically expressed in follicle-associated epithelium2007
- Author(s)
  Date, Y., Ebisawa, M., Kawano, K., Fukuda, S Hase, K., Tsuneda, S., Itoh, K., Ohno, H.
- Organizer
  第37回日本免疫学会学術集会
- Year and Date
  2007-11-21
- Data Source
  KAKENHI-PROJECT-19390143
[Presentation] Identification of molecules expressed in FAE and M cells to be involved in mucosal immunity.2007
- Author(s)
  Ohno, H.他
- Organizer
  第37回日本免疫学会学術集会
- Place of Presentation
  東京
- Year and Date
  2007-11-21
- Data Source
  KAKENHI-PROJECT-15079101
[Presentation] Endogenous prion protein expressed on M cells: A potential antigen uptake receptor2007
- Author(s)
  Nakato, G., Fukuda, S., Takatsu, H., Murakami, T., Kawano, K., Hase, K., Ohno, H.
- Organizer
  第37回日本免疫学会学術集会
- Year and Date
  2007-11-21
- Data Source
  KAKENHI-PROJECT-19390143
[Presentation] Activation-induced cytidine deaminase deficiency causes severe gastritis with mucosal hyperplasia2007
- Author(s)
  Hase, K., Itoh, K., Ebisawa, M., Ohshima, S., Fagarasan, S., Ohno, H.
- Organizer
  13^<th> International Congress of mucosal Immunology
- Year and Date
  2007-07-10
- Data Source
  KAKENHI-PROJECT-19390143
[Presentation] Analysis of epithelial-specific AP-1B-deficient mice2007
- Author(s)
  Nakato, G., Yamashita, T., Yonemura, S., Sugihara, K., Nakatsu, F., Hase, K., Murakami, T., Asano, M., Ohno, H.
- Organizer
  第40回日本発生生物学会・第59回日本細胞生物学会合同大会
- Year and Date
  2007-05-30
- Data Source
  KAKENHI-PROJECT-19390143
[Presentation] Identification of CD11c^+CD19^+ cells in the mucosa-associated lymphoid tissues: A potential role in M cell development2007
- Author(s)
  Ebisawa, M., Hase, K., Ohno, H.
- Organizer
  13^<th> International Congress of mucosal Immunology
- Year and Date
  2007-07-10
- Data Source
  KAKENHI-PROJECT-19390143
[Presentation] M-Sec: the M cell-specific Sec family molecule that regulates tunneling nanotubule (TNT) formation2007
- Author(s)
  Hase, K., Takatsu, H., Kawano, S., Ohno, H.
- Organizer
  第37回日本免疫学会総会・学術集会
- Year and Date
  2007-11-20
- Data Source
  KAKENHI-PROJECT-19390143
[Presentation] Host-Gut Microbial Communication in Host Defense and Immunity
- Author(s)
  Ohno H
- Organizer
  The Microbiome Forum: Asia
- Place of Presentation
  Kuala Lumpur, Malaysia
- Year and Date
  2015-03-19 – 2015-03-20
- Invited
- Data Source
  KAKENHI-PROJECT-24249029
[Presentation] Function and differentiation of M cells, a unique subset of intestinal epithelium for antigen-uptake
- Author(s)
  Ohno H
- Organizer
  第88回日本細菌学会　（International Symposium)
- Place of Presentation
  岐阜県岐阜市・長良川国際会議場
- Year and Date
  2015-03-26 – 2015-03-28
- Invited
- Data Source
  KAKENHI-PROJECT-24249029
[Presentation] 宿主-腸内フローラ相互作用
- Author(s)
  大野博司
- Organizer
  第３５回日本食品微生物学会学術集会（教育講演）
- Place of Presentation
  大阪府堺市・大阪府立大学中百舌鳥キャンパス
- Year and Date
  2014-09-18 – 2014-09-19
- Invited
- Data Source
  KAKENHI-PROJECT-24249029
[Presentation] 食品・腸内細菌と生体防御・腸管免疫系
- Author(s)
  大野博司
- Organizer
  日本食品免疫学会設立１０周年記念学術大会
- Place of Presentation
  東京都文京区・東京大学伊藤謝恩ホール
- Year and Date
  2014-10-16 – 2014-10-17
- Invited
- Data Source
  KAKENHI-PROJECT-24249029
[Presentation] 腸内細菌と代謝調節
- Author(s)
  大野博司
- Organizer
  第８７回日本内分泌学会学術総会（教育講演）
- Place of Presentation
  福岡県福岡市・福岡国際会議場・福岡サンパレス
- Year and Date
  2014-04-24 – 2014-04-26
- Invited
- Data Source
  KAKENHI-PROJECT-24249029
[Presentation] 腸内フローラと生体防御・免疫系：統合オミクス手法によるアプローチ
- Author(s)
  大野博司
- Organizer
  第４６回日本小児感染症学会学術集会（特別講演）
- Place of Presentation
  東京都新宿区・京王プラザホテル
- Year and Date
  2014-10-18 – 2014-10-19
- Invited
- Data Source
  KAKENHI-PROJECT-24249029
[Presentation] Integrative multi-omics approach for analyzing gut ecosystem
- Author(s)
  Ohno H
- Organizer
  第18回腸内細菌学会　（International Symposium)
- Place of Presentation
  東京都文京区・東京大学伊藤国際学術研究センター
- Year and Date
  2014-06-11 – 2014-06-12
- Invited
- Data Source
  KAKENHI-PROJECT-24249029
[Presentation] 統合オミクス手法による宿主―腸内フローラ相互作用の解析
- Author(s)
  大野博司
- Organizer
  第46回日本動脈硬化学会総会・学術集会
- Place of Presentation
  東京都新宿区・京王プラザホテル
- Year and Date
  2014-07-10 – 2014-07-11
- Invited
- Data Source
  KAKENHI-PROJECT-24249029
[Presentation] 腸エコシステムと疾患・生体防御
- Author(s)
  大野博司
- Organizer
  第３５回日本肥満学会　(教育講演)
- Place of Presentation
  宮崎県宮崎市・シーガイアコンベンションセンター
- Year and Date
  2014-10-24 – 2015-10-25
- Invited
- Data Source
  KAKENHI-PROJECT-24249029
[Presentation] Gut microbiome in the host defense and gut immune regulation
- Author(s)
  Ohno H
- Organizer
  16th Congress of the Korean Scoiety of Surgical Metabolism and Nutrition & 2015 International Symposium
- Place of Presentation
  Seoul, Korea
- Year and Date
  2015-03-13 – 2015-03-14
- Invited
- Data Source
  KAKENHI-PROJECT-24249029
[Presentation] Gut microbe-derived butyrate can induce colonic Treg differentiation
- Author(s)
  Ohno H
- Organizer
  Cold Spring Harbor Conferences Asia 2014: Frontiers of Immunology in Health & Diseases
- Place of Presentation
  Suzhou, China
- Year and Date
  2014-09-02 – 2014-09-06
- Invited
- Data Source
  KAKENHI-PROJECT-24249029

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Ohno Hiroshi 大野 博司

OHNO Hiroshi 大野 博司

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宿主ー腸内細菌叢相互作用が宿主の病理に及ぼす影響の研究Principal Investigator

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The impact of gut microbiota on autoimmune diseasesPrincipal Investigator

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腸炎における粘膜障害治癒に関与する腸内細菌の同定とそのメカニズムの解明Principal Investigator

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Differentiation and function of M cells, a unique intestinal epithelial cell subset for untigen uptakePrincipal Investigator

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Comprehensive understanding of a unique intestinal epithelial M cells specialized for luminal particulate antigen uptakePrincipal Investigator

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Funtion and differentiation of a specialized subset of intestinal epithelial M cellsPrincipal Investigator

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Ohno Hiroshi 大野博司

OHNO Hiroshi 大野博司