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Hashizume Ryotaro  橋詰 令太郎

… Alternative Names

橋詰 令太郎  ハシヅメ リョウタロウ

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Researcher Number 50456662
Other IDs
  • ORCIDhttps://orcid.org/0000-0002-9237-029X
Affiliation (Current) 2022: 三重大学, 医学系研究科, 講師
Affiliation (based on the past Project Information) *help 2021: 三重大学, 医学系研究科, 助教
2016 – 2018: 三重大学, 医学系研究科, 助教
2017: 三重大学, 大学院医学系研究科, 助教
2014 – 2015: 三重大学, 医学(系)研究科(研究院), 助教
Review Section/Research Field
Principal Investigator
Experimental pathology / Pediatrics / Basic Section 48040:Medical biochemistry-related
Except Principal Investigator
Biological pharmacy / Human genetics
Keywords
Principal Investigator
トリソミー / 染色体 / 心筋再生 / 細胞質分裂 / 二核化 / プロテオミクス / 細胞周期 / 細胞分裂 / ダウン症候群 / 染色体工学 … More / iPS細胞 / CRISPR/Cas / ゲノム編集 / 再生医学 / 遺伝学 / トリソミックレスキュー / Down症候群 / 染色体消去 / CRISPR … More
Except Principal Investigator
がん / ゲノム不安定性 / 抗癌剤 / トリソミックレスキュー / ハプロタイプフェイジング / 核型正常化 / CRISPR/Cas9 / ゲノム編集 / Cre-loxP / 遺伝子 / 染色体治療 Less
  • Research Projects

    (5 results)
  • Research Products

    (6 results)
  • Co-Researchers

    (20 People)
  •  Establishing the type I CRISPR platform for extra chromosome elimination through epigenetic modulationPrincipal Investigator

    • Principal Investigator
      橋詰 令太郎
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 48040:Medical biochemistry-related
    • Research Institution
      Mie University
  •  Proof of concept study of a novel excess chromosome elimination therapy to ameliorate and prevent trisomy 21 associated complicationsPrincipal Investigator

    • Principal Investigator
      Hashizume Ryotaro
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Mie University
  •  Trisomic rescue induction by allele-specific chromosome breakage using genome editing technique

    • Principal Investigator
      Hara Mari
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Human genetics
    • Research Institution
      Mie University
  •  ゲノム不安定性を示すがん細胞を標的とした抗がんアプローチの確立

    • Principal Investigator
      Kuroda Taruho
    • Project Period (FY)
      2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Biological pharmacy
    • Research Institution
      Mie University
  •  Myocardial regeneration research based on cell-cycle progression of the adult myocytePrincipal Investigator

    • Principal Investigator
      Hashizume Ryotaro
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Experimental pathology
    • Research Institution
      Mie University

All 2019 2018 2015

All Journal Article Presentation

  • [Journal Article] Renal papillary tip extract stimulates BNP production and excretion from cardiomyocytes.2018

    • Author(s)
      Goto I, Okamoto R, Hashizume R, Suzuki N, Ito R, Yamanaka K, Saito H, Kiyonari H, Tawara I, Kageyama Y, Ogihara Y, Ali Y, Yamada N, Katayama N, Ito M
    • Journal Title

      PLoS One

      Volume: 13

    • DOI

      10.1371/journal.pone.0197078

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K09923, KAKENHI-PROJECT-16K09964
  • [Journal Article] Possibility of venoarterial extracorporeal membranous oxygenator being a bridging therapy for hemodynamic deterioration of pulmonary tumor thrombotic microangiopathy prior to initiating chemotherapy2018

    • Author(s)
      Iwashita Y, Maruyama K. et al.
    • Journal Title

      Medicine (Baltimore)

      Volume: 37

    • DOI

      10.1097/md.0000000000012169

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K11075, KAKENHI-PROJECT-18K08916, KAKENHI-PROJECT-16K09964, KAKENHI-PROJECT-16K20384
  • [Journal Article] Tenascin-C may accelerate cardiac fibrosis by activating macrophages via the integrin αVβ3/nuclear factor-κB/interleukin-6 axis.2015

    • Author(s)
      Shimojo N, Hashizume R, Kanayama K, Hara M, Suzuki Y, Nishioka T, Hiroe M, Yoshida T, Imanaka-Yoshida K.
    • Journal Title

      Hypertension.

      Volume: 66 Pages: 757-766

    • DOI

      10.1161/hypertensionaha.115.06004

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26670189, KAKENHI-PROJECT-15K08344
  • [Presentation] 染色体消去によるtrisomy 21のhaplotype phasing方法構築2019

    • Author(s)
      橋詰 令太郎、脇田 幸子、原 万里、柴山 道登、宮川 世志幸
    • Organizer
      第18回日本再生医療学会
    • Data Source
      KAKENHI-PROJECT-16K09964
  • [Presentation] ゲノム編集技術を用いた染色体再編成による染色体排除は、トリソミー細胞の染色体に対する高精度phasingを可能とする2018

    • Author(s)
      脇田幸子、原万里、吉田利通、橋詰令太郎
    • Organizer
      日本人類遺伝学会第63回大会
    • Data Source
      KAKENHI-PROJECT-16K09964
  • [Presentation] 染色体消去による21番染色体の chromosome phasingの試み-Haplotype phasing of trisomy 21 by chromosome elimination-2018

    • Author(s)
      脇田幸子、原万理、橋詰令太郎
    • Organizer
      遺伝子診療学会(25)
    • Data Source
      KAKENHI-PROJECT-16K09964
  • 1.  Hara Mari (30176383)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 5 results
  • 2.  Miyagawa yoshitaka (90415604)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 1 results
  • 3.  脇田 幸子 (20782981)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 3 results
  • 4.  Kuroda Taruho (00391946)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  Takanari Hiroki (70723253)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  Ichishi Masako (80632372)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  河野 光雄 (00234097)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  Shimojo Naoshi (70410751)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 9.  Inui masafumi (20643498)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  緒方 藍歌 (70718311)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  倉橋 浩樹 (30243215)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  北畠 康司 (80506494)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  Kokubo Yasumasa
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  Okamoto Takayuki
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 15.  IMAI HIROSHI
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 16.  吉田 利通
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 17.  片山 直之
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 18.  丸山 一男
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 19.  丸山 淳子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 20.  鈴木 圭
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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