Hashizume Ryotaro 橋詰令太郎

… Alternative Names

Researcher Number	50456662
Other IDs	https://orcid.org/0000-0002-9237-029X
Affiliation (Current)	2022: 三重大学, 医学系研究科, 講師
Affiliation (based on the past Project Information) *help	2021: 三重大学, 医学系研究科, 助教 2016 – 2018: 三重大学, 医学系研究科, 助教 2017: 三重大学, 大学院医学系研究科, 助教 2014 – 2015: 三重大学, 医学(系)研究科(研究院), 助教
Review Section/Research Field	Principal Investigator Experimental pathology / Pediatrics / Basic Section 48040:Medical biochemistry-related Except Principal Investigator Biological pharmacy / Human genetics
Keywords	Principal Investigator トリソミー / 染色体 / 心筋再生 / 細胞質分裂 / 二核化 / プロテオミクス / 細胞周期 / 細胞分裂 / ダウン症候群 / 染色体工学 … More Except Principal Investigator がん / ゲノム不安定性 / 抗癌剤 / トリソミックレスキュー / ハプロタイプフェイジング / 核型正常化 / CRISPR/Cas9 / ゲノム編集 / Cre-loxP / 遺伝子 / 染色体治療 Less

Establishing the type I CRISPR platform for extra chromosome elimination through epigenetic modulationPrincipal Investigator
- Principal Investigator
  
  橋詰令太郎
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  Mie University
Proof of concept study of a novel excess chromosome elimination therapy to ameliorate and prevent trisomy 21 associated complicationsPrincipal Investigator
- Principal Investigator
  
  Hashizume Ryotaro
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Mie University
Trisomic rescue induction by allele-specific chromosome breakage using genome editing technique
- Principal Investigator
  
  Hara Mari
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Human genetics
- Research Institution
  Mie University
ゲノム不安定性を示すがん細胞を標的とした抗がんアプローチの確立
- Principal Investigator
  
  Kuroda Taruho
- Project Period (FY)
  2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Biological pharmacy
- Research Institution
  Mie University
Myocardial regeneration research based on cell-cycle progression of the adult myocytePrincipal Investigator
- Principal Investigator
  
  Hashizume Ryotaro
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Experimental pathology
- Research Institution
  Mie University

All 2019 2018 2015

All Journal Article Presentation

[Journal Article] Renal papillary tip extract stimulates BNP production and excretion from cardiomyocytes.2018
- Author(s)
  Goto I, Okamoto R, Hashizume R, Suzuki N, Ito R, Yamanaka K, Saito H, Kiyonari H, Tawara I, Kageyama Y, Ogihara Y, Ali Y, Yamada N, Katayama N, Ito M
- Journal Title
  
  PLoS One
  
  Volume: 13
- DOI
  10.1371/journal.pone.0197078
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09923, KAKENHI-PROJECT-16K09964
[Journal Article] Possibility of venoarterial extracorporeal membranous oxygenator being a bridging therapy for hemodynamic deterioration of pulmonary tumor thrombotic microangiopathy prior to initiating chemotherapy2018
- Author(s)
  Iwashita Y, Maruyama K. et al.
- Journal Title
  
  Medicine (Baltimore)
  
  Volume: 37
- DOI
  10.1097/md.0000000000012169
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11075, KAKENHI-PROJECT-18K08916, KAKENHI-PROJECT-16K09964, KAKENHI-PROJECT-16K20384
[Journal Article] Tenascin-C may accelerate cardiac fibrosis by activating macrophages via the integrin αVβ3/nuclear factor-κB/interleukin-6 axis.2015
- Author(s)
  Shimojo N, Hashizume R, Kanayama K, Hara M, Suzuki Y, Nishioka T, Hiroe M, Yoshida T, Imanaka-Yoshida K.
- Journal Title
  
  Hypertension.
  
  Volume: 66 Pages: 757-766
- DOI
  10.1161/hypertensionaha.115.06004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26670189, KAKENHI-PROJECT-15K08344
[Presentation] 染色体消去によるtrisomy 21のhaplotype phasing方法構築2019
- Author(s)
  橋詰令太郎、脇田幸子、原万里、柴山道登、宮川世志幸
- Organizer
  第18回日本再生医療学会
- Data Source
  KAKENHI-PROJECT-16K09964
[Presentation] ゲノム編集技術を用いた染色体再編成による染色体排除は、トリソミー細胞の染色体に対する高精度phasingを可能とする2018
- Author(s)
  脇田幸子、原万里、吉田利通、橋詰令太郎
- Organizer
  日本人類遺伝学会第63回大会
- Data Source
  KAKENHI-PROJECT-16K09964
[Presentation] 染色体消去による21番染色体の chromosome phasingの試み-Haplotype phasing of trisomy 21 by chromosome elimination-2018
- Author(s)
  脇田幸子、原万理、橋詰令太郎
- Organizer
  遺伝子診療学会(25)
- Data Source
  KAKENHI-PROJECT-16K09964

1. Hara Mari (30176383)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
2. Miyagawa yoshitaka (90415604)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
3. 脇田幸子 (20782981)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
4. Kuroda Taruho (00391946)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. Takanari Hiroki (70723253)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. Ichishi Masako (80632372)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 河野光雄 (00234097)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. Shimojo Naoshi (70410751)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. Inui masafumi (20643498)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 緒方藍歌 (70718311)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 倉橋浩樹 (30243215)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 北畠康司 (80506494)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. Kokubo Yasumasa

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. Okamoto Takayuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
15. IMAI HIROSHI

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 吉田利通

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 片山直之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 丸山一男

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 丸山淳子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 鈴木圭

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hashizume Ryotaro 橋詰 令太郎

橋詰 令太郎 ハシヅメ リョウタロウ

Research Projects

Research Products

Co-Researchers

Establishing the type I CRISPR platform for extra chromosome elimination through epigenetic modulationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Proof of concept study of a novel excess chromosome elimination therapy to ameliorate and prevent trisomy 21 associated complicationsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Trisomic rescue induction by allele-specific chromosome breakage using genome editing technique

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ゲノム不安定性を示すがん細胞を標的とした抗がんアプローチの確立

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Myocardial regeneration research based on cell-cycle progression of the adult myocytePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Renal papillary tip extract stimulates BNP production and excretion from cardiomyocytes.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Possibility of venoarterial extracorporeal membranous oxygenator being a bridging therapy for hemodynamic deterioration of pulmonary tumor thrombotic microangiopathy prior to initiating chemotherapy2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Tenascin-C may accelerate cardiac fibrosis by activating macrophages via the integrin αVβ3/nuclear factor-κB/interleukin-6 axis.2015

Author(s)

Journal Title

DOI

Data Source

[Presentation] 染色体消去によるtrisomy 21のhaplotype phasing方法構築2019

Author(s)

Organizer

Data Source

[Presentation] ゲノム編集技術を用いた染色体再編成による染色体排除は、トリソミー細胞の染色体に対する高精度phasingを可能とする2018

Author(s)

Organizer

Data Source

[Presentation] 染色体消去による21番染色体の chromosome phasingの試み-Haplotype phasing of trisomy 21 by chromosome elimination-2018

Author(s)

Organizer

Data Source

Hashizume Ryotaro 橋詰令太郎

橋詰令太郎ハシヅメリョウタロウ