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SUDA Toshio  須田 年生

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Researcher Number 60118453
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Affiliation (based on the past Project Information) *help 2014 – 2022: 熊本大学, 国際先端医学研究機構, 卓越教授
2015: 熊本大学, 学内共同利用施設等, その他
2010 – 2014: Keio University, 医学部, 教授
2010 – 2011: 慶応義塾大学, 医学部, 教授
2002 – 2008: Keio Univ, Sch, Med, Professor, 医学部, 教授 … More
2000 – 2002: Institute of Molecular Embryology and Genetics, KUMAMOTO UNIVERSITY Professor, 発生医学研究センター, 教授
1992 – 1999: 熊本大学, 医学部, 教授
1993: 能本大学, 医学部, 教授
1991 – 1992: Jichi Medi. School, Dept. Medi., Associate Prof., 医学部, 助教授
1991: 自治医科大学, 講師
1989 – 1990: 自治医科大学, 血液内科, 講師
1986 – 1990: Jichi Medical School ・ Lecturer, 医学部, 講師
1989: 自治医科大学, 血液学教室, 講師
1988: Division of Hematology, Department of Medicine, Jichi Medical School, 血液学, 講師
1986 – 1987: 自治医科大学, 講師
1986: 自治医大, 医学部, 講師
1985: 自治医科大学, 医, 講師 Less
Review Section/Research Field
Principal Investigator
Hematology / Hematology / Biological Sciences / Broad Section I / Biological Sciences / Biological Sciences
Except Principal Investigator
Hematology / General physiology / Hematology / Basic Section 50020:Tumor diagnostics and therapeutics-related … More / Basic Section 54010:Hematology and medical oncology-related / Basic Section 44020:Developmental biology-related / Developmental biology / Molecular biology / Morphological basic dentistry / Biological Sciences / Biological Sciences Less
Keywords
Principal Investigator
造血幹細胞 / 血液幹細胞 / Hemangioblast / ニッチ / 骨芽細胞 / 血管新生 / AGM領域 / 受容体型チロシンキナーゼ / FACS / RANK … More / TEK / CD34 / 活性酸素 / RANKL / 破骨細胞 / 血管内皮細胞 / 自己複製能 / 間葉系幹細胞 / Angiopoietin / TIE / STK / 低酸素 / TIE2受容体 / Side Population / M-CSF / 転写調節 / シグナル伝達 / osteoblast / アンジオポエチン / ephrin-B2 / ALCAM / ES細胞 / 細胞接着 / 自己複製 / TYRO3 / インテグリン / 造血環境 / gp130 / 多分化能 / GATA / MSP / RON / SCF / c-kit / 遺伝子導入 / 幹細胞ニッチ / 白血病幹細胞 / 細胞周期 / TIE2 / ATM / 造血前駆細胞 / Stochastic Model / 転写制御 / 幹細胞 / 分化制御 / IL-6 / 遺伝子操作 / HTK結合因子(HTKL) / HTK受容体 / TEK遺伝子 / TIE遺伝子 / ストロマ細胞 / B細胞 / 造血微小環境(ニッチ) / 造血微小環境(ニッチ) / 造血微小循環(ニッチ) / ミトコンドリア / 不均等分裂 / 造血微小環境(ニッチ) / metabolism / angiogenesis / stem cell niche / bone marrow / Angptl / anegiopoietin / Tie2受容体 / AML1 / 血管幹細胞 / 幹細胞分化転換 / リンパ管新生 / 酸化ストレス / 代謝 / 骨髄 / アンジオポエチン様分子 / vascular invasion / perichondrium / mesenchymal stem cell / osteoclast / ARPs / 骨髄造血 / 造骨・破骨 / ALCAM接着分子 / 骨髄間葉組織 / アンジオポエチンファミリー / 血管進入 / 軟骨膜 / TIE2 receptor / Angiopoietin(Ang-1) / Maintenance of stemness / Interaction between HSCs and ECs / Cell adhesion / Vitellin artery / Microenvironment / シグナルトラップ法 / 自己複製因子 / 造血支持組織 / 受容体型チロシンキナーゼTIE2 / 二次造血 / 一次造血 / 末分化維持 / 造血-血管内皮相互作用 / アンジオポエチン(Ang-1) / 未分化維持 / 造血-血管内皮相互間作用 / 卵黄動脈 / 微小環境(ニッシェ) / Home page / Abstract / Gene transfer / Transcriptional regulation / Signal transductiom / Cell differentiation / Stemness / Hematopoietic Stem Cell / 分化決定 / 多能性造血幹細胞 / 幹細胞システム / Evi-1転写制御因子 / 負のシグナル伝達機構 / STAT3 / 造血システム / HIVベクター / クロストーク / 転写 / シグナル / 相互変換 / 再生医学研究 / ホームページ作成 / 冊子作成 / シグナル制御 / 未分化性維持機構 / c-KitィイD1+ィエD1Mac-1ィイD1dullィエD1c-FmsィイD1+ィエD1 cells / osteoblasts / Osteoclasts / GAS6 / ビタミンD3 / STK(RON) / ODF / TRAP / c-FMS / Mac-1 / KIT / AGM region / アンギオポエチレン / IL-6R / receptor tyroshine kinases / hemotopoietic stem cells / 転写因子 / 幹細胞増幅 / 蛍光細胞分離装置 / 赤血球分化 / 細胞運命決定因子 / IL-6可溶性受容体 / Reccptor tyrosine kinases / Endothelial cells / Hematopoietic Stem Cells / RON遺伝子 / HTK / Stem cells / Cーkit / コロニー刺激活性 / ILー7 / ILー6 / ILー5 / ILー4 / B220抗原 / T細胞リセプター / LGL / リンパ球の初期分化 / G-CSF / GMーCSF / ILー3 / 遺伝子ブリッキング / レトロウィルス / 形質転換 / 分化 / 炎症性サイトカイン / 巨核球 / 幹細胞制御 / 人工ニッチ / 幹細胞老化 / 細胞回転 / 細胞代謝 / ニッチ因子 / プロスタグランディン / 炎症 / PO / Fbw / 多発性骨髄腫 / IL-2Rα / VE-カドヘリン / CML / 血液腫瘍疾患 / 癌幹細胞 / thrombopoietin / mpl / Angiopoiedn-1 / Thrombopoietin / Mpl / Angiopoietin-1 / Tie2 / 遺伝子破壊マウス / エフリン / 血管形成 / Sir2 / 細胞周期遺伝子 / p21 / Main Population / 遺伝子発現 / 血管前駆細胞 / 細胞接着・解離 / 動脈系血管内皮細胞 / 静脈系血管内皮細胞 / 赤血球系 / ephrinB2 / EbhB4 / degenerative PCR / DNA microarray / GM-CSF / C-fos / 核内因子 / 娘細胞 / GFP / GATA-1転写因子 / 不均等分化 / PECAM-1 / 脾コロニー / OP9 ストロマ細胞 / 造血動態 / GFPトランスジェニックマウス / 自己複製型因子 / 新規ケモカイン / 受容体型チコシンキナーゼ / 対外増幅 / Hemagioblast / CD34分子 / ヒト造血幹細胞アッセイ系 / ヒト細胞移植系 / 骨髄移植療法 / 血管新生因子 / -マウス / AML-1- / VEカドヘリン / AGM細胞 / 臍帯血造血幹細胞 / 可溶性IL-6受容体 / 未分化性維持 / 血管新生療法 / 造血幹細胞移植 / C(-)HTK / 赤血球増加 / ストローマ細胞 / 赤血球前駆細胞 / 発生と自己複製 / 計画研究 / 平成10年度発足予定重点領域研究 / commonγ / 造血微小環境 / CD34抗原 / 胎児肝細胞 / IL-7 … More
Except Principal Investigator
造血幹細胞 / 造血因子 / Csk / 血液幹細胞 / CD34 / シグナル伝達 / 転写因子 / チロシンリン酸化 / 染色体 / 細胞分裂 / トランスジェニックマウス / エピジェネティクス / 多能性幹細胞 / Flk-1 / 発生 / インターロイキン3 / 染色体分析 / 増殖因子 / 血管内皮細胞 / 幹細胞 / CD36 / Src型チロシンキナーゼ / 多核化 / Src型キナーゼ / チロシンキナーゼ / Hyl / 受容体型チロシンキナーゼ / cーkit / 骨髄移植 / 代謝 / 分化 / 初期発生 / クロマチン / 再生医学 / Eph / 血管新生 / c-Kit / TIE2 / Csk homologous kinase (Chk) / Gas6 / Tyro3 / FGFR-1 / VEGF / Osteoclasts / hemopoietic stem cells / 破骨細胞 / カルシウムイオン / 造血細胞コロニー / 白血病 / 癌遺伝子 / 細胞分化 / アンジオポエチン / 血管生物学 / ES細胞 / ニッシェ / Csk homologous kinase(chk) / トロンビン / 血小板 / M期 / Hyl) / 巨核球 / チロシンリン酸化酵素 / 造血調節因子 / レセプターチロシンキナーゼ / 生殖細胞 / stem cell factor / GーCSF / ストロ-マ細胞 / 自家骨髄移植 / 細胞外小胞 / 細胞老化 / 胃がん / ストローマ / 抗PD-1抗体 / 多様性 / CAFs / 胃癌 / 腫瘍微小環境 / 細胞代謝 / 静止性 / トロンボポエチン / 静止期 / ミトコンドリア / 着床 / ナイーブ型 / アミノ酸代謝 / ライソソーム / リソソーム / 多能性 / 胚性幹細胞 / クロマチンリモデリング因子 / TERT / BRM / BRG1 / クロマチンリモデリング / 発現制御 / 初期胚 / ポリコーム / リプログラミング / ヒストン修飾 / 減数分裂 / 生殖 / 転写 / 哺乳類 / systems biology / RNA-seq / Systems biology / Epigenomics / Transcriptomics / MET / OVOL2 / 遺伝子発現 / epithelial cell / transcription factor / chromatin states / ATAC-seq / CAGE / ZEB1 / TGFbeta / EMT / Chromosome analysis / Single colony / Juvenile-CML / Ph^1-positive ALL / Pluripotent stem cell / Hemopoietic progenitor / 単一コロニー / 若年性慢性骨髄性白血病 / TAM(transient abnormal myelopoiesis) / Ph^1(+)ALL / 慢性骨髄性白血病 / 白血病芽球コロニー / NFS-60 / FCC-P2 / electroporation / autocrine growth / tumorigenicity / malignant phenotype / gene transfection / 無制限増殖能 / エレクトロポレーション / 遺伝子導入 / 癌形質(白血病性形質) / 分化異常 / 白血病幹細胞 / 自律増殖機構 / 増殖因子依存性増殖 / 無限増殖能 / HL-60 / differentiation-induction / alpha-sialoglyceride / alpha-sialocholesterol / gangliosides / glycosphingolipids / シアル酸 / グリコシド結合 / HL-60細胞株 / 分化誘導活性 / ヒト骨髄性白血病細胞 / シアロ糖脂質 / レチノイン酸耐性HLー60変異株 / 分化誘導 / シアログリセリド / シアロコレステロール / 合成シアロ糖化合物 / 薬剤耐性変異株 / 増殖制御 / 3分化誘導 / 骨髄性白血病 / ガングリオシド / lymphocyte differerentiation / hemopoietic stromal cells / megakaryoblastic cell line / insertion of hemopoietic factor genes / hemopoietic factors / 単細胞培養 / 無血清培養 / インターリューキン6 / インターリューキン5 / MN血液型 / リンパ球の超源 / 造血支株細胞 / 巨核球性白血病株 / 造血因子遺伝子挿入 / 幹細胞の濃縮 / 発癌ウイルス / 巨核球産生 / インターリユキン5 / リンパ球の起源 / Interleukin-3(IL-3) / Hemopoietic Growth factors / Cellular oncogene c-myb rearrangement / Abelson murine leukemia virus(A-MuLV) / Plasmid gAE1A / Exogenous gene introduction / Pricking method / NFS-60細胞株 / 細胞性腫瘍遺伝子c-myb / Abelson白血病ウイルス / プラスミドgAE1A / 外来性遺伝子導 / プリッキング法 / Signal transduction / Anatomy / Development and Differentiation / Regenerative medicine / Cell and Tissue / 生殖幹細胞 / ニッチ / 細胞表面蛋白 / 生殖幹細胸 / 解剖学 / 発生、分化 / 細胞、組織 / Ephrin Signaling / Angiogenesis / Vasculogenesis / 分子生物学 / Ephrin-B2 / 心血管系 / Transgenic mouse / WHCHE(CXCL15) / Endothelial cell / Chemokine / 遺伝子破壊マウス / 赤芽球造血 / 胎仔肝臓 / アデノウイルス / WECHE / 造血細胞 / WECHE(CXCL15) / ケモカイン / Angiopoietin-1 / endothelial cell / development / hematopoietic stem cell / AGM / アンジオエポエチン / P-Sp / thrombin / Src family kinase Lyn / platelet / integrin VLA5 / fibronectin / cell spreading / translocation / 細胞接着 / インテグリン VLA5 / Lyn / フィブロネクチン / 細胞伸展 / インテグリンVLA5 / Src型チロシンキナーゼLyn / Csk homologous kinase(Chk) / BMP-2 / Bone resorption / Tyro-3リガンド Gas6 / チロシンキナーゼ Tyro-3 / 破骨細胞の活性化機構 / 生存率 / 骨吸収 / FLK-1 / FLT-1 / BMF-2 / Bone rescorption / signal transduction / Kno-ck-out mouse / Transcription factor / Impact factor / Hemoietic factor / Death signal / Differentiation signal / Hemopoietic stem / 造血幹細胞移植 / 造血支持細胞 / 造血微小環境 / 造血因子レセプター / サイトカイン / 造血幹細胞の精製 / 増殖の制御 / ノックアウト・マウス / 受容体チロシンキナーゼ / 分化制御 / Jak-Stat系 / 増殖因子受容体 / シグナル伝進 / 遺伝子改変動物 / インパクトファクター / 死のシグナル / 分化シグナル / anti-leukemic cell antibody / spleen colony / mucopolysaccharide / c-kit / monoclonal antibody / hemopoietic growth factors / DIF / CD33 / WGA / 抗白血病細胞抗体 / 脾コロニ- / ムコ多糖 / Cーkit / モノクロ-ナル抗体 / 細胞内カルシウム測定 / パッチクランプ法 / カルシウムチャンネル / 細胞増殖分化 / 未分化若幼血液細胞 / 前白血病状態 / 大顆粒リンパ球 / 多分化能幹細胞 / 自己再生産能力 / モザイクマウス / 単一細胞の解析 / イオンチャンネル / 血液細胞 / 細胞増殖・分化 / 組換ウイルス / 細胞増殖 / 細胞培養 / 突然変異マウス / 分子標的治療 / 幹細胞ニッチ / 癌幹細胞 / 生体分子 / 細胞・組織 / 癌 / リンパ節転移 / リンパ管腫 / LYVE-2 / V6GF / LYVE-1 / リンパ管 / 末分化性維持機構 / 造的幹細胞 / ポリコーム遺伝子産物 / ATM / ホーミング / 多分化能 / 自己複製 / 可塑性 / 未分化性 / テクノロジー / 再生医療 / 未分化性維持機構 / 分裂気紡鍾糸 / Srcチロシンキナーゼ / トランスロケーション / Csk homologous kinase (Chk / 細胞内局在 / Csk homolosous kinase(Chl / 染色体分配 / loxP / Cre / 細胞標的化 / GM-CSF遺伝子導入腎癌細胞 / 免疫遺伝子治療法 / 細胞障害性Tリンパ球(CTL)活性 / リンパ球輸注療法 / tie / 造血調節因子レセプター / インターロイキン / マスト細胞腫 / 突然変異動物 / Stem-cell-factor / c-kitがん原遺伝子 / インターロイキン11 / トランスフェリンレセプター / ストロマ細胞 / P53遺伝子 / RTーPCR / ステムセルファクタ-(SCF) / インタ-ロイキン11 / 胸腺ストロ-マ細胞 / M‐CSFレセプタ- / p53遺伝子 / c‐kit / 未梢血幹細胞移植 / SCF / T細胞 / 巨核球コロニ- / GーCSFレセプタ- / gp55遺伝子 / 細胞周期 / 末梢血単核細胞移植 / ILー6 / heterogeneity / c-abl蛋白 / BCR gene / minor-bcr-1 / Major-bcr-1 / Ph陽性慢性骨髄性白血病簾 / Ph陽性急性白血病 / ストローマ細胞 / 末梢血幹細胞移植 Less
  • Research Projects

    (78 results)
  • Research Products

    (289 results)
  • Co-Researchers

    (126 People)
  •  Development of anti-stromal therapeutic strategy based on histological molecular subtyping of gastric cancer stroma.

    • Principal Investigator
      Ishimoto Takatsugu
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Kumamoto University
  •  Metabolic and epigenetic regulation of pluripotency via FLCN-RAG-TFE axis

    • Principal Investigator
      Endoh Mitsuhiro
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 44020:Developmental biology-related
    • Research Institution
      Kumamoto University
  •  Self-renewal capacity of hematopoietic stem cells and mitochondrial metabolismPrincipal Investigator

    • Principal Investigator
      SUDA Toshio
    • Project Period (FY)
      2018 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Review Section
      Broad Section I
    • Research Institution
      Kumamoto University
  •  Cell metabolism determines the megakaryocyte lineage fate of hematopoietic stem cells

    • Principal Investigator
      Nakamura-Ishizu Ayako
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54010:Hematology and medical oncology-related
    • Research Institution
      Tokyo Women's Medical University
      Kumamoto University
  •  Regulation of preimplantation embryonic fate and plasticity by the PRC1 Polycomb group complex

    • Principal Investigator
      Endoh Mitsuhiro
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Developmental biology
    • Research Institution
      Kumamoto University
  •  Analyzing transcription factor network and chromatin regulation during epithelial-to-mesenchymal transition

    • Principal Investigator
      WATANABE KAZUHIDE
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Molecular biology
    • Research Institution
      Institute of Physical and Chemical Research
  •  Homeostasis of hematopoietic stem cells and its breakdownPrincipal Investigator

    • Principal Investigator
      SUDA Toshio
    • Project Period (FY)
      2014 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Hematology
    • Research Institution
      Kumamoto University
  •  HSC regulation by TERT-binding proteins, chromatin remodeling factor BRG1/BRM

    • Principal Investigator
      Nitta Eriko
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Chiba University
  •  Nicher Regulation for Normal Hemopoietic Stem Cells and Leukemic Stem CellsPrincipal Investigator

    • Principal Investigator
      SUDA Toshio
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Hematology
    • Research Institution
      Keio University
  •  Development of Novel Treatment Strategies Targeting Cancer Stem Cells

    • Principal Investigator
      AKASHI Koichi
    • Project Period (FY)
      2010 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Kyushu University
  •  Analysis of Niche Regulation for Cancer Stem CellsPrincipal Investigator

    • Principal Investigator
      TOSHIO Suda
    • Project Period (FY)
      2010 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Keio University
  •  ニッチによる幹細胞の運命制御Principal Investigator

    • Principal Investigator
      須田 年生
    • Project Period (FY)
      2010
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Hematology
    • Research Institution
      Keio University
  •  Regulation of Hematopoietic Stem Cell Division in a NichePrincipal Investigator

    • Principal Investigator
      SUDA Toshio
    • Project Period (FY)
      2004 – 2008
    • Research Category
      Grant-in-Aid for Specially Promoted Research
    • Review Section
      Biological Sciences
    • Research Institution
      Keio University
  •  破骨・造骨カップリング制御による骨破壊腫瘍の制御Principal Investigator

    • Principal Investigator
      須田 年生
    • Project Period (FY)
      2003
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Keio University
  •  リンパ管システムに関わる分子の網羅的スクリーニング

    • Principal Investigator
      OIKE Yuichi
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Hematology
    • Research Institution
      Keio University
  •  幹細胞の可塑性と未分化性維持機構

    • Principal Investigator
      中内 啓光
    • Project Period (FY)
      2002 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  造血幹細胞と血管幹細胞における遺伝子発現の系統的解析Principal Investigator

    • Principal Investigator
      須田 年生
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Hematology
    • Research Institution
      Keio University
  •  Transdifferentiation of hematopoietic stem cells and endothelial progenitorsPrincipal Investigator

    • Principal Investigator
      OIKE Yuichi, 須田 年生
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Hematology
    • Research Institution
      Keio University
  •  Molecular analysis of common mechanisms that are crucial for maintenance of hematopoietic stem cells and male germ stem cells.

    • Principal Investigator
      OHBO Kazuyuki
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hematology
    • Research Institution
      Keio University
  •  赤血球産生における微小環境の検討―膜通過性Eph受容体の機能解析―Principal Investigator

    • Principal Investigator
      須田 年生
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Hematology
    • Research Institution
      Kumamoto University
  •  造血前駆細胞における分化決定機構の解析-マクロファージと破骨細胞の分岐-Principal Investigator

    • Principal Investigator
      須田 年生
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Hematology
    • Research Institution
      Kumamoto University
  •  Differentiation of Mesenchymal Stem Cells in Bone MarrowPrincipal Investigator

    • Principal Investigator
      SUDA Toshio
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hematology
    • Research Institution
      Keio University
      Kumamoto University
  •  Analysis of novel chemokine "WHCHE" in development and hematopoies

    • Principal Investigator
      OHNEDA Osamu
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      University of Tsukuba
      Kumamoto University
  •  Investigation of the role of Eph/Ephrin signaling in vasculogenesis and angiogenesis

    • Principal Investigator
      OIKE Yuichi
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Institution
      Kumamoto University
  •  造血幹細胞分化における不均等分裂の解析Principal Investigator

    • Principal Investigator
      須田 年生
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Hematology
    • Research Institution
      Kumamoto University
  •  CSK類似chkチロシンキナーゼによる細胞増殖制御機構の解析

    • Principal Investigator
      山口 直人
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Kumamoto University
  •  造血幹細胞の発生と自己複製Principal Investigator

    • Principal Investigator
      須田 年生
    • Project Period (FY)
      1998 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Review Section
      Biological Sciences
    • Research Institution
      Kumamoto University
  •  GFPトランスジェニックマウスからの細胞移植による造血動態の解析Principal Investigator

    • Principal Investigator
      須田 年生
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Hematology
    • Research Institution
      Kumamoto University
  •  Self Renew and Cell Differentiation in Hemopoietic SystemPrincipal Investigator

    • Principal Investigator
      SUDA Toshio
    • Project Period (FY)
      1998 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Keio University
      Kumamoto University
  •  Molecular analysis for microenvironment of hematopoietic cells.Principal Investigator

    • Principal Investigator
      SUDA Toshio
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (A).
    • Research Field
      Hematology
    • Research Institution
      KUMAMOTO UNIVERSITY
  •  Analysis of molecular mechanism in hematopoietic stem cell development

    • Principal Investigator
      TAKAKURA Nobuyuki
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Hematology
    • Research Institution
      Kumamoto University
  •  Csk類似Chkチロシンキナーゼによる細胞分裂異常の分子機構

    • Principal Investigator
      山口 直人
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kumamoto University
  •  造血幹細胞研究の方向性の検討Principal Investigator

    • Principal Investigator
      須田 年生
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hematology
    • Research Institution
      Kumamoto University
  •  造血前駆細胞からストローマ細胞への作用:HTK受容体結合因子の機能解析Principal Investigator

    • Principal Investigator
      須田 年生
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Hematology
    • Research Institution
      Kumamoto University
  •  Study of roles of receptor tyrosine kinases in regulating osteoclast function.

    • Principal Investigator
      KUMEGAWA Masayoshi
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Meikai University
  •  Cloning and functional analysis of specific molecules of osteoclastPrincipal Investigator

    • Principal Investigator
      SUDA Toshio
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hematology
    • Research Institution
      Kumamoto University
  •  Distinct roles of Chk and Csk in regulation of Src family kinases in hematopoietic cells

    • Principal Investigator
      YAMAGUCHI Naoto
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Kumamoto University
  •  CskファミリーHylチロシンキナーゼによる細胞分裂異常の分子機構

    • Principal Investigator
      山口 直人
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kumamoto University
  •  非受容体型チロシンキナーゼHylとCskの機能分担と血小板活性化

    • Principal Investigator
      山口 直人
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Kumamoto University
  •  common γ鎖ターゲティングマウスにおける造血幹細胞増加の機序Principal Investigator

    • Principal Investigator
      須田 年生
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Hematology
    • Research Institution
      Kumamoto University
  •  Functional analyzes for common receptor tyrosine kinases of hematopoietic stem cells and vascular endothelial cellsPrincipal Investigator

    • Principal Investigator
      SUDA Toshio
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hematology
    • Research Institution
      Kumamoto University
  •  新Cskファミリー「Hylチロシンキナーゼ」による細胞分裂異常の分子機構

    • Principal Investigator
      山口 直人
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kumamoto University
  •  血液幹細胞の巨核球への増殖分化に関わる新規非受容体型チロシンキナーゼの研究

    • Principal Investigator
      山口 直人
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Kumamoto University
  •  がんに対する細胞移植/遺伝子治療の基礎的研究

    • Principal Investigator
      浅野 茂隆
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  血液幹細胞特異的チロシンキナーゼを介するシグナル伝達

    • Principal Investigator
      山口 直人
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Kumamoto University
  •  Regulation of Hemopoietic Stem Cells and Its Clinical Application

    • Principal Investigator
      KITAMURA Yukihiko
    • Project Period (FY)
      1994 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  Purification and ampliefication of hematopoietic stem cellsPrincipal Investigator

    • Principal Investigator
      SUDA Toshio
    • Project Period (FY)
      1994 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kumamoto University
  •  c-kitがん原遺伝子の発現と機能

    • Principal Investigator
      KITAMURA Yukihiko
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Osaka University
  •  血液幹細胞に特異的に発現されるTIE受容体のリガンドの検索Principal Investigator

    • Principal Investigator
      須田 年生
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kumamoto University
  •  造血幹細胞制御と臨床応用に向けての基礎研究

    • Principal Investigator
      北村 幸彦
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      Hematology
    • Research Institution
      Osaka University
  •  血液幹細胞特異抗原、tieとCD34を介するシグナル伝達機構

    • Principal Investigator
      山口 直人
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Kumamoto University
  •  Cloning of Seel-renewal factor receptors from hemopoietic stem cellsPrincipal Investigator

    • Principal Investigator
      SUDA Toshio
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Hematology
    • Research Institution
      Kumamoto University School of Medicine
  •  自己造血幹細胞移植におけるがん治療の基礎的臨床的研究

    • Principal Investigator
      浅野 茂隆
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      The University of Tokyo
  •  血液細胞産生の調節に関する基礎的解析ー幹細胞の濃縮・純化とその機能の解析

    • Principal Investigator
      溝口 秀昭
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tokyo Women's Medical University
  •  ヒト純化造血幹細胞の増殖・分化に対するcーkitおよびcーkitリガンドの作用

    • Principal Investigator
      笠原 忠
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Jichi Medical University
  •  血液幹細胞に特異的に発現される分子の発現調節とその機能解析Principal Investigator

    • Principal Investigator
      SUDA Toshio
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Hematology
    • Research Institution
      Jichi Medical School
  •  血液細胞産生の調節に関する基礎的解析ー幹細胞の濃縮・純化とその機能の解析ー

    • Principal Investigator
      溝口 秀昭
    • Project Period (FY)
      1990 – 1992
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tokyo Women's Medical University
  •  ヒト血液幹細胞の純化とその自己複製に関する研究Principal Investigator

    • Principal Investigator
      須田 年生
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Jichi Medical University
  •  血液細胞産生の調節に関する基礎的解析ー幹細胞の濃縮・純化とその機能の解析

    • Principal Investigator
      溝口 秀昭
    • Project Period (FY)
      1990 – 1992
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tokyo Women's Medical University
  •  自己造血幹細胞移植によるがん治療の基礎的研究

    • Principal Investigator
      ASANO Shigetaka
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      The University of Tokyo
  •  Ph陽性白血病及びPh陽性血液腫瘍に於ける、分子生物学研究

    • Principal Investigator
      SATO Yuko
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Utsunomiya University
  •  血液幹細胞のクロ-ンソ-ティングによるBリンパ球初期分化の研究Principal Investigator

    • Principal Investigator
      須田 年生
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Jichi Medical University
  •  自己造血幹細胞移植によるがん治療の基礎的臨床的研究

    • Principal Investigator
      浅野 茂隆
    • Project Period (FY)
      1989 – 1991
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      The University of Tokyo
  •  Isolation concentration, and preservation of hemopoietic stem cells and its clinical

    • Principal Investigator
      MIURA Yasusada
    • Project Period (FY)
      1989 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      Hematology
    • Research Institution
      Jichi Medical School
  •  遺伝子組換えB細胞増殖因子の造血作用Principal Investigator

    • Principal Investigator
      須田 年生
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Jichi Medical University
  •  血液幹細胞のクローン性増殖から白血病への進展

    • Principal Investigator
      北村 幸彦
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Osaka University
  •  血液細胞の増殖・分化におけるカルシウムイオンの役割

    • Principal Investigator
      宮崎 俊一
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      General physiology
    • Research Institution
      Jichi Medical University
  •  in vitroにおける多能性血液幹細胞からのリンパ球分化Principal Investigator

    • Principal Investigator
      須田 年生
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Jichi Medical University
  •  Autocrine Proliferation and Differentiation-Capacities of Leukemic Cells, and Molecular Analyses of Leukemic Phenotypes

    • Principal Investigator
      SAITO Masaki
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Hematology
    • Research Institution
      Jichi Medical School
  •  The study of hematologic malignancy by using the simultanous analysis of morphology and karyotypes on leukemic hemopoietic cells.

    • Principal Investigator
      YUKO Sato M.D.
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Health Administration Center, Utsunomiya University
  •  血液幹細胞のクローン性増殖から白血病への進展

    • Principal Investigator
      北村 幸彦
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Osaka University
  •  造血幹細胞の分化と白血病はどのようにかかわりをもつか?

    • Principal Investigator
      三浦 恭定
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Jichi Medical University
  •  血液細胞の増殖・分化におけるイオンフラックスの役割

    • Principal Investigator
      宮崎 俊一
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      General physiology
    • Research Institution
      Jichi Medical University
  •  血液幹細胞の正常分化と形質転換Principal Investigator

    • Principal Investigator
      須田 年生
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Jichi Medical University
  •  Studies on multipotent stem cell clifferentiation using newly developed techniques an its clinical applications.

    • Principal Investigator
      MIURA Yasusada
    • Project Period (FY)
      1986 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      Hematology
    • Research Institution
      JICHI MEDICAL SCHOOL
  •  Bioactive Sialoglycosphingolipids(Gangliosides) and Their Related Amphipathic Sialoglycocompounds:Fundamental Studies and Applications of Anti-Leukemic(Differentiation-Inducing) Activities

    • Principal Investigator
      SAITO Masaki
    • Project Period (FY)
      1986 – 1988
    • Research Category
      Grant-in-Aid for Developmental Scientific Research
    • Research Field
      Hematology
    • Research Institution
      Jichi Medical School
  •  単離した造血幹細胞へのマウス白血病ウィルスの感染,癌遺伝子のトランスフェクションPrincipal Investigator

    • Principal Investigator
      須田 年生
    • Project Period (FY)
      1985
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Jichi Medical University
  •  Establishment of Hemopoietic Stem Cell Lines By Introduction of Oncogenes and Biochemical Studies on Mechanisms of Hemopoietic Cell Differentiation Using the Established Cell Lines

    • Principal Investigator
      SAITO Masaki
    • Project Period (FY)
      1985 – 1986
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Hematology
    • Research Institution
      Jichi Medical School

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2008 2007 2006 2005 2004 2003 2002 Other

All Journal Article Presentation Book Patent

  • [Book] Stem Cells Volume 12014

    • Author(s)
      Cheong J-W, Nakamura-Ishizu A, Nitta E, Suda T
    • Total Pages
      18
    • Publisher
      CRC Press
    • Data Source
      KAKENHI-PROJECT-26221309
  • [Book] The Stem Cell Research Community, StemBook2010

    • Author(s)
      Arai F, Suda T
    • Total Pages
      11
    • Publisher
      StemBook, ed
    • Data Source
      KAKENHI-PLANNED-22130004
  • [Book] Hematopoietic Stem Cell Biology(Motonari Kondo ed.)2010

    • Author(s)
      Iwasaki H, Suda T
    • Total Pages
      251
    • Publisher
      Hematopoietic Stem Cells and Their Niche
    • Data Source
      KAKENHI-ORGANIZER-22130001
  • [Journal Article] Revisiting PD-1 to target leukaemic stem cells2023

    • Author(s)
      Yang Chong、Suda Toshio
    • Journal Title

      Nature Cell Biology

      Volume: 25 Issue: 1 Pages: 17-19

    • DOI

      10.1038/s41556-022-01040-5

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H05284
  • [Journal Article] Independent origins of fetal liver haematopoietic stem and progenitor cells2022

    • Author(s)
      Yokomizo Tomomasa、Ideue Takako、Morino-Koga Saori、Tham Cheng Yong、Sato Tomohiko、Takeda Naoki、Kubota Yoshiaki、Kurokawa Mineo、Komatsu Norio、Ogawa Minetaro、Araki Kimi、Osato Motomi、Suda Toshio
    • Journal Title

      Nature

      Volume: 609 Issue: 7928 Pages: 779-784

    • DOI

      10.1038/s41586-022-05203-0

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08758, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-18H05284, KAKENHI-PROJECT-19K07668, KAKENHI-PROJECT-23K21285, KAKENHI-PROJECT-23K24165
  • [Journal Article] Tumor microenvironmental 15‐PGDH depletion promotes fibrotic tumor formation and angiogenesis in pancreatic cancer2022

    • Author(s)
      Bu L, Yonemura A, Yasuda-Yoshihara N, Uchihara T, Ismagulov G, Takasugi S, Yasuda T, Okamoto Y, Kitamura F, Akiyama T, Arima K, Itoyama R, Zhang J, Fu L, Hu X, Wei, F, Arima Y, Moroishi T, Nishiyama K, Sheng G, Mukunoki T, Otani J, Baba H, Ishimoto T
    • Journal Title

      Cancer Science

      Volume: 113 Issue: 10 Pages: 3579-3592

    • DOI

      10.1111/cas.15495

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21KK0153, KAKENHI-PROJECT-20H03531, KAKENHI-PROJECT-21H02490, KAKENHI-PROJECT-20K09038, KAKENHI-PROJECT-21K19535
  • [Journal Article] Targeting chemoresistance in Xp11.2 translocation renal cell carcinoma using a novel polyamide?chlorambucil conjugate2022

    • Author(s)
      Funasaki Shintaro、Mehanna Sally、Ma Wenjuan、Nishizawa Hidekazu、Kamikubo Yasuhiko、Sugiyama Hiroshi、Ikeda Shuji、Motoshima Takanobu、Hasumi Hisashi、Linehan W. Marston、Schmidt Laura S.、Ricketts Chris、Suda Toshio、Oike Yuichi、Kamba Tomomi、Baba Masaya
    • Journal Title

      Cancer Science

      Volume: n/a Issue: 7 Pages: 2352-2367

    • DOI

      10.1111/cas.15364

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K09694, KAKENHI-PROJECT-18H05284, KAKENHI-PROJECT-18H02938, KAKENHI-PROJECT-20K09560, KAKENHI-PROJECT-21K19721, KAKENHI-PROJECT-21K09374, KAKENHI-PROJECT-22K19533, KAKENHI-PROJECT-23K24474
  • [Journal Article] A Myb enhancer-guided analysis of basophil and mast cell differentiation2022

    • Author(s)
      Matsumura Takayoshi、Totani Haruhito、Gunji Yoshitaka、Fukuda Masahiro、Yokomori Rui、Deng Jianwen、Rethnam Malini、Yang Chong、Tan Tze King、Karasawa Tadayoshi、Kario Kazuomi、Takahashi Masafumi、Osato Motomi、Sanda Takaomi、Suda Toshio
    • Journal Title

      Nature Communications

      Volume: 13 Issue: 1 Pages: 7064-7064

    • DOI

      10.1038/s41467-022-34906-1

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K08114, KAKENHI-PROJECT-21K19514, KAKENHI-PROJECT-18H05284, KAKENHI-PROJECT-19K07668, KAKENHI-PROJECT-23K24165
  • [Journal Article] ATP citrate lyase controls hematopoietic stem cell fate and supports bone marrow regeneration2022

    • Author(s)
      Umemoto Terumasa、Johansson Alban、Ahmad Shah Adil Ishtiyaq、Hashimoto Michihiro、Kubota Sho、Kikuchi Kenta、Odaka Haruki、Era Takumi、Kurotaki Daisuke、Sashida Goro、Suda Toshio
    • Journal Title

      The EMBO Journal

      Volume: 41 Issue: 8 Pages: 1-20

    • DOI

      10.15252/embj.2021109463

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03688, KAKENHI-PROJECT-21K08421, KAKENHI-PROJECT-22K15660, KAKENHI-PROJECT-18H05284, KAKENHI-PROJECT-19K16263, KAKENHI-PROJECT-21K16272
  • [Journal Article] Depth-targeted intracortical microstroke by two-photon photothrombosis in rodent brain2022

    • Author(s)
      Fukuda Masahiro、Matsumara Takayoshi、Suda Toshio、Hirase Hajime
    • Journal Title

      Neurophotonics

      Volume: 9 Issue: 02

    • DOI

      10.1117/1.nph.9.2.021910

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H05284, KAKENHI-PROJECT-20K08961
  • [Journal Article] Single-Cell Atlas of Lineage States, Tumor Microenvironment, and Subtype-Specific Expression Programs in Gastric Cancer2022

    • Author(s)
      Kumar V, Ramnarayanan K, Sundar R, Padmanbahan N, Srivastava S, Koiwa M, Yasuda T, Koh V, Huang K, Tay S, Ho S, Tan A, Ishimoto T
    • Journal Title

      Cancer Discovery

      Volume: 12 Issue: 3 Pages: 670-691

    • DOI

      10.1158/2159-8290.cd-21-0683

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21KK0153, KAKENHI-PROJECT-20H03531, KAKENHI-PROJECT-21K19535
  • [Journal Article] Stromal reprogramming through dual PDGFRα/β blockade boosts the efficacy of anti-PD-1 immunotherapy in fibrotic tumors.2022

    • Author(s)
      T. Akiyama, T. Yasuda, T. Uchihara, N. Yasuda-Yoshihara, BJY. Tan, A. Yonemura, T. Semba, J. Yamasaki, Y. Komohara, K. Ohnishi, F. Wei, L. Fu, J. Zhang, F. Kitamura, K. Yamashita, K. Eto, S. Iwagami, H. Tsukamoto, T. Umemoto, M. Masuda, O. Nagano, Y. Satou, H. Saya, P. Tan, H. Baba, T. Ishimoto
    • Journal Title

      Cancer Res.

      Volume: 83 Issue: 5 Pages: 753-770

    • DOI

      10.1158/0008-5472.can-22-1890

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K07370, KAKENHI-PROJECT-22K20836, KAKENHI-PROJECT-20H00518, KAKENHI-PROJECT-20H03531, KAKENHI-PROJECT-21H02788, KAKENHI-PROJECT-20K07690, KAKENHI-PROJECT-21K19416, KAKENHI-PROJECT-21K19535, KAKENHI-PROJECT-23K08051, KAKENHI-PROJECT-21KK0153, KAKENHI-PROJECT-23K27463
  • [Journal Article] MEK inhibition suppresses metastatic progression of <i>KRAS</i> ‐mutated gastric cancer2022

    • Author(s)
      Yamasaki Juntaro、Hirata Yuki、Otsuki Yuji、Suina Kentaro、Saito Yoshiyuki、Masuda Kenta、Okazaki Shogo、Ishimoto Takatsugu、Saya Hideyuki、Nagano Osamu
    • Journal Title

      Cancer Science

      Volume: 113 Issue: 3 Pages: 916-925

    • DOI

      10.1111/cas.15244

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K16315, KAKENHI-PROJECT-21H02766, KAKENHI-PROJECT-21K19416, KAKENHI-PROJECT-21K19417, KAKENHI-PROJECT-20K18174, KAKENHI-PROJECT-22K20836, KAKENHI-PROJECT-21KK0153, KAKENHI-PROJECT-20H03531, KAKENHI-PROJECT-21K19535
  • [Journal Article] Mitochondria transfer mediates stress erythropoiesis by altering the bioenergetic profiles of early erythroblasts through CD472022

    • Author(s)
      Yang Chong、Yokomori Rui、Chua Lee Hui、Tan Shi Hao、Tan Darren Qiancheng、Miharada Kenichi、Sanda Takaomi、Suda Toshio
    • Journal Title

      Journal of Experimental Medicine

      Volume: 219 Issue: 12 Pages: 1-16

    • DOI

      10.1084/jem.20220685

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H05284
  • [Journal Article] Bone marrow imaging reveals the migration dynamics of neonatal hematopoietic stem cells2022

    • Author(s)
      Takihara Yuji、Higaki Takumi、Yokomizo Tomomasa、Umemoto Terumasa、Ariyoshi Kazunori、Hashimoto Michihiro、Sezaki Maiko、Takizawa Hitoshi、Inoue Toshihiro、Suda Toshio、Mizuno Hidenobu
    • Journal Title

      Communications Biology

      Volume: 5 Issue: 1 Pages: 776-776

    • DOI

      10.1038/s42003-022-03733-x

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08758, KAKENHI-PROJECT-22K19549, KAKENHI-ORGANIZER-22H05092, KAKENHI-PROJECT-18H05284, KAKENHI-PROJECT-20H03289, KAKENHI-PROJECT-20K09774, KAKENHI-PLANNED-18H05492
  • [Journal Article] Intracellular MUC20 variant 2 maintains mitochondrial calcium homeostasis and enhances drug resistance in gastric cancer2022

    • Author(s)
      Fu Lingfeng、Yonemura Atsuko、Yasuda-Yoshihara Noriko、Umemoto Terumasa、Zhang Jun、Yasuda Tadahito、Uchihara Tomoyuki、Akiyama Takahiko、Kitamura Fumimasa、Yamashita Kohei、Okamoto Yuya、Bu Luke、Wei Feng、Hu Xichen、Liu Yang、Ajani Jaffer A.、Tan Patrick、Baba Hideo、Ishimoto Takatsugu
    • Journal Title

      Gastric Cancer

      Volume: 25 Issue: 3 Pages: 542-557

    • DOI

      10.1007/s10120-022-01283-z

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03688, KAKENHI-PROJECT-20H03531, KAKENHI-PROJECT-20K09038, KAKENHI-PROJECT-21K19535
  • [Journal Article] Mitochondria Turnover and Lysosomal Function in Hematopoietic Stem Cell Metabolism2021

    • Author(s)
      Mochizuki-Kashio Makiko、Shiozaki Hiroko、Suda Toshio、Nakamura-Ishizu Ayako
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 22 Issue: 9 Pages: 4627-4627

    • DOI

      10.3390/ijms22094627

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H05284, KAKENHI-PROJECT-21K08425
  • [Journal Article] Mitochondria transfer from erythroblasts to their macrophage niche via tunneling nanotubes.2021

    • Author(s)
      Yang C, Endoh M, Tan DQ, Nakamura-Ishizu A, Takihara Y, Matsumura T, Suda T.
    • Journal Title

      British Journal of Haematology

      Volume: In press

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K06693
  • [Journal Article] Conflicting metabolic alterations in cancer stem cells and regulation by the stromal niche2021

    • Author(s)
      Yasuda T, I Ishimoto T, Baba H
    • Journal Title

      Regenerative Therapy

      Volume: 17 Pages: 8-12

    • DOI

      10.1016/j.reth.2021.01.005

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H03531, KAKENHI-PROJECT-21K19535, KAKENHI-PROJECT-21KK0153
  • [Journal Article] Protocol to establish cancer-associated fibroblasts from surgically resected tissues and generate senescent fibroblasts2021

    • Author(s)
      Yasuda T, Koiwa M, Yonemura A, Akiyama T, Baba H, Ishimoto T
    • Journal Title

      STAR Protocols

      Volume: 2 Issue: 2 Pages: 100553-100553

    • DOI

      10.1016/j.xpro.2021.100553

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H03531, KAKENHI-PROJECT-20K08985, KAKENHI-PROJECT-21K19535, KAKENHI-PROJECT-21KK0153
  • [Journal Article] Myeloma cells self-promote migration by regulating TAB1-driven TIMP-1 expression in mesenchymal stem cells2021

    • Author(s)
      Rethnam Malini、Tan Darren Qiancheng、Suda Toshio
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 534 Pages: 843-848

    • DOI

      10.1016/j.bbrc.2020.10.093

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H05284
  • [Journal Article] Inflammation-driven senescence-associated secretory phenotype in cancer-associated fibroblasts enhances peritoneal dissemination2021

    • Author(s)
      Yasuda T, Koiwa M, Yonemura A, Miyake K, Kariya R, Kubota S, Yokomizo-Nakano T, Yasuda-Yoshihara N, Uchihara T, Itoyama R, Bu L, Fu L, Arima K, Izumi D, Iwagami S, Eto K, Iwatsuki M, Baba Y, Yoshida N, Ohguchi H, Okada S, Matsusaki K, Sashida G, Takahashi A, Tan P, Baba H, Ishimoto T.
    • Journal Title

      Cell Reports

      Volume: 34 Issue: 8 Pages: 108779-108779

    • DOI

      10.1016/j.celrep.2021.108779

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K08543, KAKENHI-PROJECT-19K16749, KAKENHI-PROJECT-19H03507, KAKENHI-PROJECT-20H03531, KAKENHI-PROJECT-20K08985, KAKENHI-PROJECT-21K19535, KAKENHI-PROJECT-21K16384, KAKENHI-PROJECT-21KK0153
  • [Journal Article] Autophagy is dispensable for the maintenance of hematopoietic stem cells in neonates2021

    • Author(s)
      Hashimoto Michihiro、Umemoto Terumasa、Nakamura-Ishizu Ayako、Matsumura Takayoshi、Yokomizo Tomomasa、Sezaki Maiko、Takizawa Hitoshi、Suda Toshio
    • Journal Title

      Blood Advances

      Volume: 5 Issue: 6 Pages: 1594-1604

    • DOI

      10.1182/bloodadvances.2020002410

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08758, KAKENHI-PROJECT-19H03688, KAKENHI-PROJECT-18J20690, KAKENHI-PROJECT-19J00952, KAKENHI-PROJECT-19K22641, KAKENHI-PROJECT-18H05284
  • [Journal Article] Lymphoid-biased hematopoietic stem cells and myeloid-biased hematopoietic progenitor cells have radioprotection activity2021

    • Author(s)
      Zhang Shanshan、O’Neill Aled、Xie Miner、Wu Peng、Wang Xiaofang、Bai Haitao、Dong Fang、Wang Jinhong、Zhang Qingyun、Suda Toshio、Ema Hideo
    • Journal Title

      Blood Science

      Volume: 3 Issue: 4 Pages: 113-121

    • DOI

      10.1097/bs9.0000000000000089

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H05284
  • [Journal Article] Prolonged maintenance of hematopoietic stem cells that escape from thrombopoietin deprivation2021

    • Author(s)
      Nakamura-Ishizu Ayako、Chin Desmond Wai Loon、Matsumura Takayoshi、Tan Darren Qiancheng、Mochizuki-Kashio Makiko、Jianwen Deng、Suda Toshio
    • Journal Title

      Blood

      Volume: 137 Issue: 19 Pages: 2609-2620

    • DOI

      10.1182/blood.2020005517

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H05284, KAKENHI-PROJECT-18K08364
  • [Journal Article] Metabolic shift to serine biosynthesis through 3-PG accumulation and PHGDH induction promotes tumor growth in pancreatic cancer2021

    • Author(s)
      Itoyama R, Yasuda-Yoshihara N, Kitamura F, Yasuda T, Bu L, Yonemura A, Uchihara T, Arima K, Hu X, Jun Z, Okamoto Y, Akiyama T, Yamashita K, Nakao Y, Yusa T, Kitano Y, Higashi T, Miyata T, Imai K, Hayashi H, Yamashita Y, Mikawa T, Kondoh H, Baba H, Ishimoto T
    • Journal Title

      Cancer Letters

      Volume: 523 Pages: 29-42

    • DOI

      10.1016/j.canlet.2021.09.007

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07887, KAKENHI-PROJECT-20K16418, KAKENHI-PROJECT-20H03531, KAKENHI-PROJECT-20K09038, KAKENHI-PROJECT-21K19535, KAKENHI-PROJECT-21K16384, KAKENHI-PROJECT-21KK0153, KAKENHI-PROJECT-20K20658
  • [Journal Article] UTX maintains functional integrity of murine hematopoietic system by globally regulating aging-associated genes.2021

    • Author(s)
      Sera Y; Nakata Y; Ueda T; Yamasaki N; Koide S; Kobayashi H; Ikeda KI; Kobatake K; Iwasaki M; Oda H; Wolff L; Kanai A; Nagamachi A; Inaba T; Sotomaru Y; Ichinohe T; Koizumi M; Miyakawa Y; Honda ZI; Iwama A; Suda T; Takubo K; Honda H
    • Journal Title

      Blood.

      Volume: 137 Issue: 7 Pages: 908-922

    • DOI

      10.1182/blood.2019001044

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K07346, KAKENHI-PROJECT-19K22546, KAKENHI-PROJECT-19K17918, KAKENHI-PROJECT-19H05653, KAKENHI-PROJECT-18H02845, KAKENHI-PROJECT-19H03693, KAKENHI-PROJECT-18K08357, KAKENHI-PROJECT-18K18196, KAKENHI-PROJECT-19K17847, KAKENHI-PROJECT-19H01056, KAKENHI-PROJECT-18H05284, KAKENHI-PROJECT-21K08378, KAKENHI-PROJECT-21K08395
  • [Journal Article] Loss of METTL3 Attenuates BPDCN Response to PRMT5 Inhibition Via Interferon Signaling2021

    • Author(s)
      Rethnam Malini、Tan Darren Qiancheng、Tan Shi Hao、Ying Li、Yang Henry、Suda Toshio
    • Journal Title

      Blood

      Volume: 138 Issue: Supplement 1 Pages: 1132-1132

    • DOI

      10.1182/blood-2021-146108

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H05284
  • [Journal Article] Mitochondria transfer from early stages of erythroblasts to their macrophage niche via tunnelling nanotubes2021

    • Author(s)
      Yang C, Endoh M, Tan DQ, Nakamura-Ishizu A, Takihara Y, Matsumura T, Suda T.
    • Journal Title

      Br J Haematol .

      Volume: 193 Issue: 6 Pages: 1260-1274

    • DOI

      10.1111/bjh.17531

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K06693, KAKENHI-PROJECT-18H05284, KAKENHI-PROJECT-20K09774
  • [Journal Article] Thrombopoietin maintains cell numbers of hematopoietic stem and progenitor cells with megakaryopoietic potential2020

    • Author(s)
      O'Neill Aled、Chin Desmond、Tan Darren、Abdul Majeed A Qilah Banu Bte、Nakamura-Ishizu Ayako、Suda Toshio
    • Journal Title

      Haematologica

      Volume: 0 Issue: 7 Pages: 0-0

    • DOI

      10.3324/haematol.2019.241406

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H05284
  • [Journal Article] Bone Marrow Transplantation Dynamics: When Progenitor Expansion Prevails2020

    • Author(s)
      Nakamura-Ishizu Ayako、Ahmad Shah Adil Ishtiyaq、Suda Toshio
    • Journal Title

      Trends in Cell Biology

      Volume: 30 Issue: 11 Pages: 835-836

    • DOI

      10.1016/j.tcb.2020.08.006

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H05284
  • [Journal Article] Hematopoietic stem cells acquire survival advantage by loss of RUNX1 methylation identified in familial leukemia2020

    • Author(s)
      Matsumura Takayoshi、Nakamura-Ishizu Ayako、Muddineni Siva Sai Naga Anurag、Tan Darren Qiancheng、Wang Chelsia Qiuxia、Tokunaga Kenji、Tirado-Magallanes Roberto、Sian Stephanie、Benoukraf Touati、Okuda Tsukasa、Asou Norio、Matsuoka Masao、Osato Motomi、Suda Toshio
    • Journal Title

      Blood

      Volume: 136 Issue: 17 Pages: 1919-1932

    • DOI

      10.1182/blood.2019004292

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07668, KAKENHI-PROJECT-19K08846, KAKENHI-PROJECT-18H05284
  • [Journal Article] Hematopoietic Stem Cell Metabolism during Development and Aging2020

    • Author(s)
      Nakamura-Ishizu Ayako、Ito Keisuke、Suda Toshio
    • Journal Title

      Developmental Cell

      Volume: 54 Issue: 2 Pages: 239-255

    • DOI

      10.1016/j.devcel.2020.06.029

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H05284, KAKENHI-PROJECT-18K08364
  • [Journal Article] Gastric Cancer Stem Cells: Current Insights into the Immune Microenvironment and Therapeutic Targets2020

    • Author(s)
      Fu L, Bu L, Yasuda T, Koiwa M, Akiyama T, Uchihara T, Baba H, Ishimoto T
    • Journal Title

      Biomedicines

      Volume: 8 Issue: 1 Pages: 7-7

    • DOI

      10.3390/biomedicines8010007

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H03531
  • [Journal Article] A FLCN-TFE3 Feedback Loop Prevents Excessive Glycogenesis and Phagocyte Activation by Regulating Lysosome Activity2020

    • Author(s)
      Mitsuhiro Endoh, Masaya Baba, Tamie Endoh, Akiyoshi Hirayama, Ayako Nakamura-Ishizu, Terumasa Umemoto, Michihiro Hashimoto, Kunio Nagashima, Tomoyoshi Soga, Martin Lang , Laura S Schmidt , W Marston Linehan, Toshio Suda
    • Journal Title

      Cell Reports

      Volume: 30 Issue: 6 Pages: 1823-1834

    • DOI

      10.1016/j.celrep.2020.01.042

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K06693, KAKENHI-PROJECT-19K22641, KAKENHI-PROJECT-18H02938, KAKENHI-PROJECT-19H03688, KAKENHI-PROJECT-18K19619, KAKENHI-PROJECT-18H05284, KAKENHI-PROJECT-16H06276
  • [Journal Article] Low-dose X-rays leave scars on human hematopoietic stem and progenitor cells: the role of reactive oxygen species2020

    • Author(s)
      Yamashita Masayuki、Suda Toshio
    • Journal Title

      Haematologica

      Volume: 105 Issue: 8 Pages: 1986-1988

    • DOI

      10.3324/haematol.2020.254292

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H05284
  • [Journal Article] Extracellular Vesicles from Cancer-Associated Fibroblasts Containing Annexin A6 Induces FAK-YAP Activation by Stabilizing β1 Integrin, Enhancing Drug Resistance2020

    • Author(s)
      Uchihara T, Miyake K, Yonemura A, Komohara Y, Itoyama R, Koiwa M, Yasuda T, Arima K, Harada K, Eto K, Hayashi H, Iwatsuki M, Iwagami S, Baba Y, Yoshida N, Yashiro M, Masuda M, Ajani Jaffer A, Tan Patrick, Baba H, Ishimoto T
    • Journal Title

      Cancer Research

      Volume: 80 Issue: 16 Pages: 3222-3235

    • DOI

      10.1158/0008-5472.can-19-3803

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K09177, KAKENHI-PROJECT-20K07690, KAKENHI-PROJECT-20K08985, KAKENHI-PROJECT-18H02694, KAKENHI-PROJECT-20H03531, KAKENHI-PROJECT-18K08543, KAKENHI-PROJECT-19K16720, KAKENHI-PROJECT-19K16749, KAKENHI-PROJECT-18H02883
  • [Journal Article] Functional diversity of cancer‐associated fibroblasts in modulating drug resistance2020

    • Author(s)
      Bu Luke、Baba Hideo、Yasuda Tadahito、Uchihara Tomoyuki、Ishimoto Takatsugu
    • Journal Title

      Cancer Science

      Volume: 111 Issue: 10 Pages: 3468-3477

    • DOI

      10.1111/cas.14578

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K08985, KAKENHI-PROJECT-20H03531
  • [Journal Article] Machine Learning of Hematopoietic Stem Cell Divisions from Paired Daughter Cell Expression Profiles Reveals Effects of Aging on Self-Renewal2020

    • Author(s)
      Arai Fumio、Stumpf Patrick S.、Ikushima Yoshiko M.、Hosokawa Kentaro、Roch Aline、Lutolf Matthias P.、Suda Toshio、MacArthur Ben D.
    • Journal Title

      Cell Systems

      Volume: 11 Issue: 6 Pages: 640-652

    • DOI

      10.1016/j.cels.2020.11.004

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08733, KAKENHI-PROJECT-19K16547, KAKENHI-PROJECT-18H05284, KAKENHI-PROJECT-20H03711, KAKENHI-PROJECT-19K22638
  • [Journal Article] Hlf marks the developmental pathway for hematopoietic stem cells but not for erythro-myeloid progenitors.,2019

    • Author(s)
      Tomomasa Yokomizo, Naoki Watanabe, Terumasa Umemoto, Junichi Matsuo, Ryota Harai, Yoshihiko Kihara, Eri Nakamura, Norihiro Tada, Tomohiko Sato, Tomoiku Takaku, Akihiko Shimono, Hitoshi Takizawa, Naomi Nakagata, Seiichi Mori, Mineo Kurokawa, Daniel Tenen, Motomi Osato, Toshio Suda, and Norio Komatsu.
    • Journal Title

      J Exp Med

      Volume: 216 Issue: 7 Pages: 1599-1614

    • DOI

      10.1084/jem.20181399

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K05691, KAKENHI-PROJECT-19K07668, KAKENHI-PROJECT-19K22641, KAKENHI-PROJECT-18K16127, KAKENHI-PROJECT-18H05284, KAKENHI-PROJECT-18H04052, KAKENHI-PROJECT-19H03688, KAKENHI-PROJECT-17K09958
  • [Journal Article] PRMT5 Modulates Splicing for Genome Integrity and Preserves Proteostasis of Hematopoietic Stem Cells.2019

    • Author(s)
      Tan DQ, Li Y, Yang C, Li J, Tan SH, Chin DWL, Nakamura-Ishizu A, Yang H, Suda T
    • Journal Title

      Cell Rep.

      Volume: 26(9) Issue: 9 Pages: 2316-2328

    • DOI

      10.1016/j.celrep.2019.02.001

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H05284
  • [Journal Article] TUBB1 dysfunction identified in inherited thrombocytopenia causes impaired proplatelet formation and genome instability2019

    • Author(s)
      Matsumura T, Nakamura-Ishizu A, Maki H, Takaoka K, Naga SSA, Muddineni A, COW CQW, Suzushima H, Kawakita M, Asou N, Matsuoka M, Kurokawa M, Osato M,, Suda T
    • Journal Title

      Brit J Haematol.

      Volume: 0 Issue: 5 Pages: 0-0

    • DOI

      10.1111/bjh.15835

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H05284, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-19K07668, KAKENHI-PROJECT-18H04052
  • [Journal Article] Sphingosine-1-phosphate signaling modulates terminal erythroid differentiation through the regulation of mitophagy2019

    • Author(s)
      Yang Chong、Hashimoto Michihiro、Lin Quy Xiao Xuan、Tan Darren Qiancheng、Suda Toshio
    • Journal Title

      Experimental Hematology

      Volume: 72 Pages: 47-59.e1

    • DOI

      10.1016/j.exphem.2019.01.004

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H05284
  • [Journal Article] High Mitochondrial Mass Is Associated With Reconstitution Capacity and Quiescence of Hematopoietic Stem Cells2019

    • Author(s)
      Yuji Takihara, Ayako Nakamura-Ishizu, Darren Qiancheng Tan, Masahiro Fukuda, Takayoshi Matsumura, Mitsuhiro Endoh, Yuichiro Arima, Desmond Wai Loon Chin, Terumasa Umemoto, Michihiro Hashimoto, Hidenobu Mizuno, Toshio Suda
    • Journal Title

      Blood Advances

      Volume: 3 Issue: 15 Pages: 2323-2327

    • DOI

      10.1182/bloodadvances.2019032169

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K06693, KAKENHI-PROJECT-19K22641, KAKENHI-PROJECT-18H05284, KAKENHI-PROJECT-19H03688
  • [Journal Article] Multifaceted roles of thrombopoietin in hematopoietic stem cell regulation2019

    • Author(s)
      Nakamura‐Ishizu Ayako、Suda Toshio
    • Journal Title

      Annals of the New York Academy of Sciences

      Volume: ー Issue: 1 Pages: 1-8

    • DOI

      10.1111/nyas.14169

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H05284, KAKENHI-PROJECT-18K08364
  • [Journal Article] Hlf expression marks the developmental pathway for hematopoietic stem cells but not for erythroid-myeloid progenitors2019

    • Author(s)
      Yokomizo T, Watanabe N, Umemoto T, Matsuo J, Harai R, Kihara Y, Koga S, Nakamura E, Tada N, Sato T, Takaku T, Shimono A, Takizawa H, Ogawa M, Nakagata N, Mori S, Kurokawa M, Tenen DG, Osato M,Suda T, Komatsu N
    • Journal Title

      J Exp. Med.

      Volume: in press

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H05284
  • [Journal Article] Dynamic changes in the niche - N-cadherin revisited: the HSC “Niche Herein”2019

    • Author(s)
      Nakamura-Ishizu A, Suda T
    • Journal Title

      Cell Stem Cell

      Volume: 24(3) Issue: 3 Pages: 355-356

    • DOI

      10.1016/j.stem.2019.02.007

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H05284
  • [Journal Article] Lack of whey acidic protein (WAP) four-disulfide core domain protease inhibitor 2 (WFDC2) causes neonatal death from respiratory failure in mice.2019

    • Author(s)
      Nakajima K, Ono M, Radovic U, Dizdarevic S, Tomizawa SI, Kuroha K, Nagamatsu G, Hoshi I, Matsunaga R, Shirakawa T, Kurosawa T, Miyazaki Y, Seki M, Suzuki Y, Koseki H, Nakamura M, Suda T, Ohbo K.
    • Journal Title

      Disease Models & Mechanisms

      Volume: 12 Pages: 40139-40139

    • DOI

      10.1242/dmm.040139

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06261, KAKENHI-PROJECT-19K23831, KAKENHI-PROJECT-18H05284, KAKENHI-PROJECT-16H06279
  • [Journal Article] Modification of the bone marrow MSC population in a xenograft model of early multiple myeloma2019

    • Author(s)
      Berlier Jessica L.、Rethnam Malini、Banu Binte Abdul Majeed A'Qilah、Suda Toshio
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 508 Issue: 4 Pages: 1175-1181

    • DOI

      10.1016/j.bbrc.2018.11.178

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H05284
  • [Journal Article] Beginning of a New Era: Mapping the Bone Marrow Niche2019

    • Author(s)
      Nakamura-Ishizu Ayako、MacArthur Ben D.、Suda Toshio
    • Journal Title

      Cell

      Volume: 177 Issue: 7 Pages: 1679-1681

    • DOI

      10.1016/j.cell.2019.05.042

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H05284
  • [Journal Article] Ageing of hematopoietic stem cells2018

    • Author(s)
      塩崎 宏子、石津 綾子、須田 年生
    • Journal Title

      Rinsho Ketsueki

      Volume: 59 Issue: 1 Pages: 3-12

    • DOI

      10.11406/rinketsu.59.3

    • NAID

      130006337958

    • ISSN
      0485-1439, 1882-0824
    • Language
      Japanese
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26221309
  • [Journal Article] Thrombopoietin metabolically primes hematopoietic stem cells to megakaryocyte lineage differentiation2018

    • Author(s)
      Nakamura-Ishizu N, Matsumura T, Stumpf PS, Umemoto T, Takizawa H, Takihara Y, O’Neil A, Majeed ABBA, MacArthur BD., Suda T
    • Journal Title

      Cell Reports

      Volume: 25(7) Issue: 7 Pages: 1772-1785

    • DOI

      10.1016/j.celrep.2018.10.059

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H05284, KAKENHI-PROJECT-15KK0350, KAKENHI-PROJECT-18K08364
  • [Journal Article] Small Maf functions in the maintenance of germline stem cells in the Drosophila testis2018

    • Author(s)
      Tan Sharon Wui Sing、Yip George W.、Suda Toshio、Baeg Gyeong Hun
    • Journal Title

      Redox Biology

      Volume: 15 Pages: 125-134

    • DOI

      10.1016/j.redox.2017.12.002

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26221309, KAKENHI-PROJECT-18H05284
  • [Journal Article] Ca(2+)-mitochondria axis drives cell division in hematopoietic stem cells2018

    • Author(s)
      Umemoto T, Hashimoto M, MatsumuraT, Nakamura-Ishizu A, Suda T
    • Journal Title

      J Exp Med.

      Volume: 218(8) Issue: 8 Pages: 2097-2113

    • DOI

      10.1084/jem.20180421

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H05284, KAKENHI-PROJECT-17K16190
  • [Journal Article] Folliculin Regulates Osteoclastogenesis Through Metabolic Regulation2018

    • Author(s)
      3.Baba M, Endoh M, Ma W, Toyama H, Hirayama A, Nishikawa K, Takubo K, Hano H, Hasumi H, Umemoto T, Hashimoto M, Irie N, Esumi C, Kataoka M, Nakagata N, Soga T, Yao M, Kamba T, Minami T, Ishii M, and Suda T.
    • Journal Title

      Journal of Bone and Mineral Research

      Volume: 33 Issue: 10 Pages: 1785-1798

    • DOI

      10.1002/jbmr.3477

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18KT0026, KAKENHI-PROJECT-18K18455, KAKENHI-PROJECT-18K19619, KAKENHI-PUBLICLY-17H05530, KAKENHI-PROJECT-18H05284, KAKENHI-PROJECT-18H02614, KAKENHI-PROJECT-18H02938, KAKENHI-PROJECT-16K07372, KAKENHI-PROJECT-16K11020, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-17H03580
  • [Journal Article] Ribosome Incorporation into Somatic Cells Promotes Lineage Transdifferentiation towards Multipotency2018

    • Author(s)
      Ito Naofumi、Katoh Kaoru、Kushige Hiroko、Saito Yutaka、Umemoto Terumasa、Matsuzaki Yu、Kiyonari Hiroshi、Kobayashi Daiki、Soga Minami、Era Takumi、Araki Norie、Furuta Yasuhide、Suda Toshio、Kida Yasuyuki、Ohta Kunimasa
    • Journal Title

      Scientific Reports

      Volume: 8 Issue: 1 Pages: 1634-1634

    • DOI

      10.1038/s41598-018-20057-1

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K07118, KAKENHI-PROJECT-16H04795, KAKENHI-PROJECT-26221309, KAKENHI-PROJECT-16K18553, KAKENHI-PROJECT-18K06264, KAKENHI-PLANNED-17H06410, KAKENHI-ORGANIZER-17H06413, KAKENHI-PROJECT-16H05440
  • [Journal Article] PCGF6-PRC1 suppresses premature differentiation of mouse embryonic stem cells by regulating germ cell-related genes.2017

    • Author(s)
      Endoh M, Endo TA, Shinga J, Hayashi K, Farcas A, Ma KW, Ito S, Sharif J, Endoh T, Onaga N, Nakayama M, Ishikura T, Masui O, Kessler BM, Suda T, Ohara O, Okuda A, Klose RJ, Koseki H.
    • Journal Title

      Elife

      Volume: 6 Pages: 27970-27970

    • DOI

      10.7554/elife.21064

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H02622, KAKENHI-PROJECT-15H05602, KAKENHI-PROJECT-16K07372, KAKENHI-PROJECT-16K14773, KAKENHI-ORGANIZER-25112001, KAKENHI-PROJECT-26221309
  • [Journal Article] The telomere binding protein Pot1 maintains haematopoietic stem cell activity with age2017

    • Author(s)
      Hosokawa Kentaro、MacArthur Ben D.、Ikushima Yoshiko Matsumoto、Toyama Hirofumi、Masuhiro Yoshikazu、Hanazawa Shigemasa、Suda Toshio、Arai Fumio
    • Journal Title

      Nature Communications

      Volume: 8(804) Issue: 1 Pages: 804-818

    • DOI

      10.1038/s41467-017-00935-4

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09907, KAKENHI-PROJECT-16K19067, KAKENHI-PROJECT-26221309, KAKENHI-PROJECT-17H04208
  • [Journal Article] Niche-mediated depletion of the normal hematopoietic stem cell reservoir by Flt3-ITD?induced myeloproliferation2017

    • Author(s)
      Mead AJ、Neo WH、Barkas N、Matsuoka S、Giustacchini A、Facchini R、Thongjuea S、Jamieson L、Booth C.A.G.、Fordham N、Di GC、Atkinson D、Chowdhury O、Repapi E、Gray N、Kharazi S、Clark S-A、Bouriez T、Woll P、Suda T、Nerlov C、Jacobsen SEW.
    • Journal Title

      The Journal of Experimental Medicine

      Volume: 214 Issue: 7 Pages: 2005-2021

    • DOI

      10.1084/jem.20161418

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26221309
  • [Journal Article] Hyperactivated mitophagy in hematopoietic stem cells2017

    • Author(s)
      Yang Chong、Suda Toshio
    • Journal Title

      Nature Immunology

      Volume: 19 Issue: 1 Pages: 2-3

    • DOI

      10.1038/s41590-017-0008-8

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26221309, KAKENHI-PROJECT-18H05284
  • [Journal Article] Functional analysis of Protection of Telomeres 1a (Pot1a) in regulation of hematopoietic stem cell aging2017

    • Author(s)
      Hosokawa K, Macarthur BD, Ikushima Y, Toyama H, Masuhiro Y, Hanazawa S, Suda T, Arai F.
    • Journal Title

      Rinsho Ketsueki

      Volume: 58 Issue: 8 Pages: 942-949

    • DOI

      10.11406/rinketsu.58.942

    • NAID

      130006067976

    • ISSN
      0485-1439, 1882-0824
    • Language
      Japanese
    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09907, KAKENHI-PROJECT-26221309
  • [Journal Article] Integrin αvβ3 enhances the suppressive effect of interferon‐γ on hematopoietic stem cells2017

    • Author(s)
      Umemoto Terumasa、Matsuzaki Yu、Shiratsuchi Yoshiko、Hashimoto Michihiro、Yoshimoto Takayuki、Nakamura‐Ishizu Ayako、Petrich Brian、Yamato Masayuki、Suda Toshio
    • Journal Title

      The EMBO Journal

      Volume: 36 Issue: 16 Pages: 2390-2403

    • DOI

      10.15252/embj.201796771

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K16190, KAKENHI-PROJECT-26221309
  • [Journal Article] Mfsd2b is essential for the sphingosine-1-phosphate export in erythrocytes and platelets2017

    • Author(s)
      Vu Thiet M.、Ishizu Ayako-Nakamura、Foo Juat Chin、Toh Xiu Ru、Zhang Fangyu、Whee Ding Ming、Torta Federico、Cazenave-Gassiot Amaury、Matsumura Takayoshi、Kim Sangho、Toh Sue-Anne E. S.、Suda Toshio、Silver David L.、Wenk Markus R.、Nguyen Long N.
    • Journal Title

      Nature

      Volume: 550 Issue: 7677 Pages: 524-528

    • DOI

      10.1038/nature24053

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26221309
  • [Journal Article] Reactive Oxygen Species and Mitochondrial Homeostasis as Regulators of Stem Cell Fate and Function2017

    • Author(s)
      Tan Darren Q.、Suda Toshio
    • Journal Title

      Antioxidants & Redox Signaling

      Volume: - Issue: 2 Pages: 149-168

    • DOI

      10.1089/ars.2017.7273

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26221309
  • [Journal Article] Acquired expression of CblQ367P in mice induces dysplastic myelopoiesis mimicking chronic myelomonocytic leukemia2017

    • Author(s)
      Nakata Y, Ueda T, Nagamachi A, Yamasaki N, Ikeda KI, Sera Y, Takubo K, Kanai A, Oda H, Sanada M, Ogawa S, Tsuji K, Ebihara Y, Wolff L, Honda ZI, Suda T, Inaba T, Honda H.
    • Journal Title

      Blood

      Volume: 129 Issue: 15 Pages: 2148-2160

    • DOI

      10.1182/blood-2016-06-724658

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26115009, KAKENHI-PROJECT-26221309, KAKENHI-PROJECT-15J06501, KAKENHI-PROJECT-15K16125, KAKENHI-PROJECT-17K08679, KAKENHI-PROJECT-15H04857, KAKENHI-PROJECT-17J05696, KAKENHI-PROJECT-16K19575
  • [Journal Article] Repopulation dynamics of single hematopoietic stem cells in mouse transplantation experiments: importance of stem cell composition in competitor cells2016

    • Author(s)
      Ema, H., Uchinomiya, K., Morita, Y., Suda, T., & Iwasa, Y.
    • Journal Title

      Journal of Theoretical Biology

      Volume: 394 Pages: 57-67

    • DOI

      10.1016/j.jtbi.2016.01.010

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-13J01212, KAKENHI-PROJECT-26221309, KAKENHI-PROJECT-25293221
  • [Journal Article] Self renewal of a purified Tie2+ hematopoietic stem cell population relies on mitochondrial clearance.2016

    • Author(s)
      Ito K, Turcotte R, Cui J, Zimmerman SE, Pinho S, Mizoguchi T, Arai F, Runnels JM, Alt C, Teruya-Feldstein J, Mar JC, Singh R, inkel T, Suda T, Lin CP, Frenette PS, Ito K
    • Journal Title

      Science

      Volume: 354(6316) Issue: 6316 Pages: 1156-1160

    • DOI

      10.1126/science.aaf5530

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26221309, KAKENHI-PROJECT-26293228, KAKENHI-PROJECT-26462826
  • [Journal Article] Setdb1 maintains hematopoietic stem and progenitor cells by restricting the ectopic activation of non-hematopoietic genes.2016

    • Author(s)
      Koide S, Oshima M, Takubo K, Yamazaki S, Nitta E, Saraya A, Aoyama K, Kato Y, Miyagi S, Nakajima-Takagi Y, Chiba T, Matsui H, Arai F, Suzuki Y, Kimura H, Nakauchi H, Suda T, Shinkai Y,Iwama A.
    • Journal Title

      Blood

      Volume: 128(5) Issue: 5 Pages: 638-649

    • DOI

      10.1182/blood-2016-01-694810

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-15H01513, KAKENHI-PLANNED-26115002, KAKENHI-PROJECT-26221309, KAKENHI-PROJECT-15H02544, KAKENHI-PROJECT-16H02661, KAKENHI-PROJECT-15J04258, KAKENHI-PROJECT-26293228, KAKENHI-PROJECT-15K09478, KAKENHI-PROJECT-16K09340, KAKENHI-PROJECT-16K09840, KAKENHI-PROJECT-16K19565, KAKENHI-PROJECT-16K20959
  • [Journal Article] Conversion of T cells to B cells by inactivation of polycomb-mediated epigenetic suppression of the B-lineage program.2016

    • Author(s)
      Ikawa T, Masuda K, Endo TA, Endo M, Isono K, Koseki Y, Nakagawa R, Kometani K, Takano J, Agata Y, Katsura Y, Kurosaki T, Vidal M, Koseki H, Kawamoto H.
    • Journal Title

      Genes. Dev.

      Volume: 30 Issue: 22 Pages: 2475-2485

    • DOI

      10.1101/gad.290593.116

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26221306, KAKENHI-PROJECT-16H02622, KAKENHI-PROJECT-15H04743, KAKENHI-PROJECT-26670136, KAKENHI-PROJECT-16K07372, KAKENHI-PROJECT-16K09870, KAKENHI-PROJECT-16K15289, KAKENHI-PROJECT-16K15215
  • [Journal Article] Loss of Folliculin Disrupts Hematopoietic Stem Cell Quiescence and Homeostasis Resulting in Bone Marrow Failure2016

    • Author(s)
      Baba M, Toyama H, Sun L, Takubo K, Suh HC, Hasumi H, Nakamura-Ishizu A, Hasumi Y, Klarmann KD, Nakagata N, Schmidt LS, Linehan WM, Suda T, Keller JR
    • Journal Title

      Stem Cells

      Volume: 34 Issue: 4 Pages: 1068-1082

    • DOI

      10.1002/stem.2293

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K14370, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-15H04975, KAKENHI-PROJECT-26221309
  • [Journal Article] Regulation of hematopoietic stem cell integrity through p53 and its related factors.2016

    • Author(s)
      Yamashita M, Nitta E, Suda T.
    • Journal Title

      Ann N Y Acad Sci.

      Volume: 印刷中 Issue: 1 Pages: 92-100

    • DOI

      10.1111/nyas.12986

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26461411, KAKENHI-PROJECT-26221309
  • [Journal Article] Maintenance of the functional integrity of mouse hematopoiesis by EED and promotion of leukemogenesis by EED haploinsufficiency2016

    • Author(s)
      Ikeda K-I, Ueda T, Yamasaki N, Nakata Y, Sera Y, Nagamachi A, Miyama T, Kobayashi H, TakuboK, Kanai A, Oda H, Wolff l, Honda Z-1, Ichinohe T, Matsubara A, Suda T, Inaba T, Honda H
    • Journal Title

      Scientific Reports

      Volume: 6 Issue: 1 Pages: 29454-29454

    • DOI

      10.1038/srep29454

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26221309, KAKENHI-PROJECT-15J06501, KAKENHI-PROJECT-26293227, KAKENHI-PROJECT-26460391, KAKENHI-PROJECT-15K16125, KAKENHI-PROJECT-16K19575
  • [Journal Article] Karigane D, Kobayashi H, Morikawa T, Ootomo Y, Sakai M, Nagamatsu G, Kubota Y, Goda N, Matsumoto M, Nishimura EK, Soga T, Otsu K, Suematsu M, Okamoto S, Suda T, Takubo K.2016

    • Author(s)
      Karigane D, Kobayashi H, Morikawa T, Ootomo Y, Sakai M, Nagamatsu G, Kubota Y, Goda N, Matsumoto M, Nishimura EK, Soga T, Otsu K, Suematsu M, Okamoto S, Suda T, Takubo K.
    • Journal Title

      Cell Stem Cell

      Volume: 19 Issue: 2 Pages: 192-204

    • DOI

      10.1016/j.stem.2016.05.013

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111003, KAKENHI-PLANNED-26115003, KAKENHI-PLANNED-26115005, KAKENHI-PROJECT-26221303, KAKENHI-PROJECT-26221309, KAKENHI-PROJECT-15H04851, KAKENHI-PROJECT-15H04861, KAKENHI-PROJECT-15K10315, KAKENHI-PROJECT-16K15507
  • [Journal Article] Human adipose tissue-derived stromal cells can differentiate into megakaryocytes and platelets by secreting endogenous thrombopoietin.2016

    • Author(s)
      Ono-Uruga Y, Tozawa K, Horiuchi T, Murata M, Okamoto S, Ikeda Y, Suda T,Matsubara Y.
    • Journal Title

      J Thromb Haemost.

      Volume: 未定 Issue: 6 Pages: 1-13

    • DOI

      10.1111/jth.13313

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26461410, KAKENHI-PROJECT-26221309
  • [Journal Article] Flt1/VEGFR1 heterozygocity causes transient embryonic edema2016

    • Author(s)
      Otowa Y, Moriwaki K, Sano K, Shirakabe M, Yonemura S, Shibuya M, Rossant J, Suda T, Kakeji Y, Hirashima M
    • Journal Title

      Scientific Report

      Volume: 6 Issue: 1 Pages: 27186-27186

    • DOI

      10.1038/srep27186

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26221309, KAKENHI-PROJECT-26460253, KAKENHI-PROJECT-16K20009
  • [Journal Article] Proliferation following tetraploidization regulates the size and number of erythrocytes in the blood flow during medaka development, as revealed by the abnormal karyotype of erythrocytes in the medaka TFDP1 mutant.2015

    • Author(s)
      Taimatsu K, Takubo K, Maruyama K, Suda T, Kudo A.
    • Journal Title

      Dev Dyn.

      Volume: 該当なし Issue: 5 Pages: 651-668

    • DOI

      10.1002/dvdy.24259

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-23689049, KAKENHI-PROJECT-26221309, KAKENHI-PROJECT-25340043, KAKENHI-PROJECT-25670788
  • [Journal Article] Hematopoietic stem cell enhancer: a powerful tool in stem cell biology2015

    • Author(s)
      Koh CP, Ng CE, Nah GS, Wang CQ, Tergaonkar V, Matsumura T, Yokomizo T , Suda T, Osato M
    • Journal Title

      Histol Histopathol.

      Volume: 30(6) Pages: 661-72

    • Data Source
      KAKENHI-PROJECT-26221309
  • [Journal Article] Integrative Analysis of the Acquisition of Pluripotency in PGCs reveals the mutually exclusive roles of Blimp-1 and AKT signaling2015

    • Author(s)
      Nagamatsu G, Saito S, Takubo K, Suda T.
    • Journal Title

      Stem Cell Reports

      Volume: S2213-6711(15) Issue: 1 Pages: 00150-2

    • DOI

      10.1016/j.stemcr.2015.05.007

    • Data Source
      KAKENHI-PROJECT-26221309
  • [Journal Article] CLEC-2 in megakaryocytes is critical for maintenance of hematopoietic stem cells in the bone marrow.2015

    • Author(s)
      Nakamura-Ishizu A, Takubo K, Kobayashi H, Suzuki-Inoue K, Suda T.
    • Journal Title

      J Exp Med.

      Volume: 212 Issue: 12 Pages: 2133-46

    • DOI

      10.1084/jem.20150057

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461399, KAKENHI-PLANNED-26115005, KAKENHI-PROJECT-26221309, KAKENHI-PROJECT-15H04861, KAKENHI-PROJECT-13J40030, KAKENHI-PROJECT-26713035
  • [Journal Article] Autonomy and non-autonomy of angiogenic cell movements revealed by experiment-driven mathematical modeling2015

    • Author(s)
      Sugihara K, Nishiyama K, Fukuhara S, Uemura A, Arima S, Kobayashi R, Kohn-Luque A, Mochizuki N, Suda T, Ogawa S, Kurihara H
    • Journal Title

      Cell Rep

      Volume: 13 Issue: 9 Pages: 1814-1827

    • DOI

      10.1016/j.celrep.2015.10.051

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26221309, KAKENHI-PROJECT-26670107, KAKENHI-PROJECT-26670394, KAKENHI-PROJECT-26670396, KAKENHI-PROJECT-25293050, KAKENHI-PROJECT-25293078, KAKENHI-PROJECT-15H02536
  • [Journal Article] Maintenance of hematopoietic stem cell integrity and regulation of leukemogenesis by p53 and its coactivator Aspp12015

    • Author(s)
      Yamashita M, Nitta E, Suda T.
    • Journal Title

      Rinsho Ketsueki

      Volume: 56 Issue: 12 Pages: 2426-2433

    • DOI

      10.11406/rinketsu.56.2426

    • NAID

      130005116917

    • ISSN
      0485-1439, 1882-0824
    • Language
      Japanese
    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26461411
  • [Journal Article] Fbxl10 overexpression in murine hematopoietic stemcells induces leukemia involving metabolic activation and upregulation of Nsg22015

    • Author(s)
      Ueda T, Nagamachi A, Takubo K, Yamasaki N, Matsui H, Kanai A, Nakata Y, Ikeda K Konuma T, Oda H, Wolff L, Honda Z, Wu X, Helin K, Iwama A, Suda T, Inaba T, Honda H.
    • Journal Title

      Blood

      Volume: 125 Issue: 22 Pages: 3437-3446

    • DOI

      10.1182/blood-2014-03-562694

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26460391, KAKENHI-PROJECT-15K16125, KAKENHI-PROJECT-26221309, KAKENHI-PROJECT-15J06501, KAKENHI-PROJECT-26860735, KAKENHI-PROJECT-26293227
  • [Journal Article] Bacterial c-di-GMP affects hematopoietic stem/progenitors and their niches through STING.2015

    • Author(s)
      Kobayashi H, Kobayashi CI, Nakamura-Ishizu A, Karigane D, Haeno H, Yamamoto KN, Sato T, Ohteki T, Hayakawa Y, Barber GN, Kurokawa M, Suda T, and Takubo K.
    • Journal Title

      Cell Reports

      Volume: 111 Issue: 1 Pages: 71-84

    • DOI

      10.1016/j.celrep.2015.02.066

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K15150, KAKENHI-PUBLICLY-15H01485, KAKENHI-PUBLICLY-15H01508, KAKENHI-ORGANIZER-26115001, KAKENHI-PLANNED-26115005, KAKENHI-PROJECT-26221309, KAKENHI-PROJECT-26253029, KAKENHI-PROJECT-15H04861, KAKENHI-PROJECT-24350087, KAKENHI-PLANNED-26115006
  • [Journal Article] Aspp1 preserves hematopoietic stem cell pool integrity and prevents malignant transformation.2015

    • Author(s)
      Yamashita M, Nitta E, Suda T.
    • Journal Title

      Cell Stem Cell.

      Volume: 17 Issue: 1 Pages: 23-34

    • DOI

      10.1016/j.stem.2015.05.013

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461411, KAKENHI-PROJECT-26221309
  • [Journal Article] Identification of drug candidate against prostate cancer from the aspect of somatic cell reprogramming.2014

    • Author(s)
      Kosaka T, Nagamatsu G, Saito S, Oya M, Suda T, Horimoto K
    • Journal Title

      Cancer Sci

      Volume: 104 Issue: 8 Pages: 1017-1026

    • DOI

      10.1111/cas.12183

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22130004, KAKENHI-PROJECT-23618011, KAKENHI-PUBLICLY-24116522, KAKENHI-PROJECT-24890230
  • [Journal Article] Telomerase Reverse Transcriptase Has an Extratelomeric Function in Somatic Cell Reprogramming2014

    • Author(s)
      Kinoshita T, Nagamatsu G, Saito S, Takubo K, Horimoto K, Suda T.
    • Journal Title

      The Journal of Biological Chemistry

      Volume: 289 Issue: 22 Pages: 15776-15787

    • DOI

      10.1074/jbc.m113.536037

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12J07121, KAKENHI-PLANNED-22130004
  • [Journal Article] Neurons limit angiogenesis by titrating VEGF in retina.2014

    • Author(s)
      Okabe K, Kobayashi S, Yamada T, Kurihara T, Tai-Nagara I, Miyamoto T, Mukouyama YS, Sato TN, Suda T, Ema M, Kubota Y
    • Journal Title

      Cell

      Volume: 159 Issue: 3 Pages: 584-596

    • DOI

      10.1016/j.cell.2014.09.025

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-12J08602, KAKENHI-ORGANIZER-22130001, KAKENHI-PLANNED-22130004, KAKENHI-PROJECT-26221309, KAKENHI-PROJECT-22229007
  • [Journal Article] Jam1a-Jam2a interactions regulate haematopoietic stem cell fate through Notch signalling.2014

    • Author(s)
      Kobayashi I, Kobayashi-Sun J, Kim AD, Pouget C, Fujita N, Suda T, Traver D.
    • Journal Title

      Nature

      Volume: 512 Issue: 7514 Pages: 319-23

    • DOI

      10.1038/nature13623

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-ORGANIZER-22130001, KAKENHI-PLANNED-22130004, KAKENHI-PROJECT-26221309
  • [Journal Article] Determining C-Myb protein levels can isolate functional hematopoietic stem cell subtypes.2014

    • Author(s)
      Sakamoto H, Takeda N, Arai F, Hosokawa K, Garcia P, Suda T, Frampton J, Ogawa M
    • Journal Title

      Stem Cells

      Volume: 33 Issue: 2 Pages: 479-490

    • DOI

      10.1002/stem.1855

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22130004, KAKENHI-PROJECT-24591400, KAKENHI-PROJECT-24689041, KAKENHI-PROJECT-25670453, KAKENHI-PROJECT-26293228, KAKENHI-PROJECT-26670471, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-26221309
  • [Journal Article] Mortalin and DJ-1 coordinately regulate hematopoietic stem cell function through the control of oxidative stress.2014

    • Author(s)
      Tai-Nagara I, Matsuoka S, Ariga H, Suda T
    • Journal Title

      Blood

      Volume: 123 Issue: 1 Pages: 41-50

    • DOI

      10.1182/blood-2013-06-508333

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-22130004, KAKENHI-PROJECT-23249053, KAKENHI-PROJECT-26221309
  • [Journal Article] Megakaryocytes are essential for HSC quiescence through the production of thrombopoietin.2014

    • Author(s)
      Nakamura-Ishizu A, Takubo K, Fujioka M, Suda T.
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 454 Pages: 353-7

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-22130001
  • [Journal Article] The analysis, roles and regulation of quiescence in hematopoietic stem cells2014

    • Author(s)
      Nakamura-Ishizu A, Takizawa H, Suda T.
    • Journal Title

      Development

      Volume: 141(24) Issue: 24 Pages: 4656-66

    • DOI

      10.1242/dev.106575

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-13J40030, KAKENHI-PLANNED-22130004, KAKENHI-PROJECT-26221309, KAKENHI-PROJECT-26713035
  • [Journal Article] Heterogeneity and hierarchy of hematopoietic stem cells.2014

    • Author(s)
      Ema H, Morita Y, Suda T
    • Journal Title

      Exp Hematol

      Volume: 42 Issue: 2 Pages: 74-82

    • DOI

      10.1016/j.exphem.2013.11.004

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-22130004, KAKENHI-PROJECT-23249053, KAKENHI-PROJECT-26221309
  • [Journal Article] Opening the door for HIF1α tuning.2014

    • Author(s)
      Takubo K and Suda T
    • Journal Title

      Blood

      Volume: 123 Issue: 2 Pages: 151-152

    • DOI

      10.1182/blood-2013-11-536995

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22130004, KAKENHI-PROJECT-23689049, KAKENHI-PUBLICLY-25118724
  • [Journal Article] Hematopoietic stem cell aging and oxidative stress.2014

    • Author(s)
      Cheong J-W, Nakamura-Ishizu A, Nitta E, Suda T
    • Journal Title

      Stem Cells

      Volume: 1 Pages: 88-105

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22130004
  • [Journal Article] Megakaryocytes are essential for HSC quiescence through the production of thrombopoietin2014

    • Author(s)
      Nakamura-Ishizu A, Takubo K, Fujioka M, Suda T.
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 454(2) Issue: 2 Pages: 353-7

    • DOI

      10.1016/j.bbrc.2014.10.095

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-13J40030, KAKENHI-PLANNED-22130004, KAKENHI-PLANNED-26115005, KAKENHI-PROJECT-26221309, KAKENHI-PROJECT-26713035
  • [Journal Article] Hematopoietic stem cell aging and oxidative stress.2014

    • Author(s)
      Cheong J-W, Nakamura-Ishizu A, Nitta E, Suda T
    • Journal Title

      Stem Cells

      Volume: 1 Pages: 88-105

    • Data Source
      KAKENHI-PROJECT-23249053
  • [Journal Article] Epiregulin enhances tumorigenicity by activating the ERK/MAPK pathway in glioblastoma.2014

    • Author(s)
      Kohsaka S, Hinohara K, Wang L, Nishimura T, Urushido M, Yachi K, Tsuda M, Tanino M, Kimura T, Nishihara H, Gotoh N, Tanaka S.
    • Journal Title

      Neuro Oncol.

      Volume: 16 Pages: 960-70

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-22130001
  • [Journal Article] Metabolic requirements for the maintenance of self-renewing stem cells.2014

    • Author(s)
      Ito K and Suda T
    • Journal Title

      Nat Rev Mol Cell Biol

      Volume: 15 Issue: 4 Pages: 243-256

    • DOI

      10.1038/nrm3772

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-22130004, KAKENHI-PROJECT-23249053, KAKENHI-PROJECT-26221309
  • [Journal Article] The IL-2/CD25 Axis Maintains Distinct Subsets of Chronic M yeloid Leukemia-initiating Cells.2014

    • Author(s)
      Kobayashi CI, Takubo K, Kobayashi H, Nakamura-Ishizu A, Honda H, Kataoka K, Kumano K, Akiyama H, Sudo T, Kurokawa M, Suda T.
    • Journal Title

      Blood

      Volume: 123 Issue: 16 Pages: 2540-2549

    • DOI

      10.1182/blood-2013-07-517847

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-11J04561, KAKENHI-ORGANIZER-22130001, KAKENHI-PLANNED-22130004, KAKENHI-PROJECT-23249053, KAKENHI-PROJECT-23591369, KAKENHI-PROJECT-23689049, KAKENHI-PUBLICLY-25118724, KAKENHI-PROJECT-25640065, KAKENHI-PROJECT-26221309, KAKENHI-PROJECT-26461170
  • [Journal Article] Hematopoietic stem cell niche: An interplay among a repertoire of multiple functional niches.2013

    • Author(s)
      Nakamura-Ishizu A and Suda T
    • Journal Title

      Biochem Biophys Acta

      Volume: 1830 Issue: 2 Pages: 2404-2409

    • DOI

      10.1016/j.bbagen.2012.08.023

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22130004, KAKENHI-PROJECT-23249053, KAKENHI-PROJECT-24790983
  • [Journal Article] OP9 bone marrow stroma cells differentiate into megakaryocytes and platelets.2013

    • Author(s)
      Matsubara Y, Ono Y, Suzuki H, Arai F, Suda T, Murata M, Ikeda Y
    • Journal Title

      PLoS One

      Volume: 8 Issue: 3 Pages: e58123-e58123

    • DOI

      10.1371/journal.pone.0058123

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22130004, KAKENHI-PROJECT-23249030, KAKENHI-PROJECT-23249053
  • [Journal Article] Enhanced Angptl/Tie2 signaling affects the differentiation and long-term repopulation ability of hematopoietic stem cells.2013

    • Author(s)
      Ikushima YM. Arai F, Nakamura Y, Hosokawa K, Kubota Y, Hirashima M, Toyama H, Suda T
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 130(1) Issue: 1 Pages: 20-25

    • DOI

      10.1016/j.bbrc.2012.11.002

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-11J04866, KAKENHI-PLANNED-22122002, KAKENHI-PLANNED-22130004, KAKENHI-PROJECT-23249053, KAKENHI-PROJECT-24689041
  • [Journal Article] Haploinsufficiency of SAMD9L, an endosome fusion facilitator, causes myeloid malignancies in mice mimicking human diseases with monosomy 7.2013

    • Author(s)
      Nagamachi A
    • Journal Title

      Cancer Cell

      Volume: 24 Issue: 3 Pages: 305-317

    • DOI

      10.1016/j.ccr.2013.08.011

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-22130001, KAKENHI-PLANNED-22130004, KAKENHI-PROJECT-23240125, KAKENHI-PROJECT-23249053, KAKENHI-PROJECT-23390252, KAKENHI-PROJECT-23689049, KAKENHI-PROJECT-24591397, KAKENHI-PUBLICLY-25118724, KAKENHI-PROJECT-25550030, KAKENHI-PROJECT-25640065
  • [Journal Article] Nucleostemin is indispensable for the maintenance and genetic stability of hematopoietic stem cells.2013

    • Author(s)
      Yamashita M, Nitta E, Nagamatsu G, Ikushima YM, Hosokawa K, Arai F, Suda T
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 441 Issue: 1 Pages: 196-201

    • DOI

      10.1016/j.bbrc.2013.10.032

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12J40105, KAKENHI-PROJECT-13J05828, KAKENHI-PLANNED-22130004, KAKENHI-PROJECT-23249053, KAKENHI-PROJECT-23618011, KAKENHI-PUBLICLY-24116522, KAKENHI-PROJECT-24689041, KAKENHI-PROJECT-25670453, KAKENHI-PROJECT-25893234
  • [Journal Article] Ex vivo maintenance of hematopoietic stem cells by quiescence induction through Fbxw7&alpha ; overexpression2011

    • Author(s)
      Iriuchishima H, Takubo K, Matsuoka S, Onoyama I, Nakayama KI, Nojima Y, Suda T
    • Journal Title

      Blood

      Volume: 117(8) Pages: 2373-7

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-22130001
  • [Journal Article] Deficiency of Rap1-binding protein RAPL causes lymphoproliferative disorders through mislocalization of p27kip12011

    • Author(s)
      Katagiri K, Ueda Y, Tomiyama T, Yasuda K, Toda Y, Ikehara S, Nakayama KI, Kinashi T
    • Journal Title

      Immunity

      Volume: 34(1) Pages: 24-38

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-22130001
  • [Journal Article] Metabolic regulation of hematopoietic stem cells in the hypoxic niche2011

    • Author(s)
      Suda T, et al
    • Journal Title

      Cell Stem Cell

      Volume: 9 Issue: 4 Pages: 298-310

    • DOI

      10.1016/j.stem.2011.09.010

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-22130001, KAKENHI-PLANNED-22130004, KAKENHI-PUBLICLY-23118527, KAKENHI-PROJECT-23249053, KAKENHI-PROJECT-23689049
  • [Journal Article] Non-canonical inhibition of DNA damage-dependent ubiquitination by OTUB12010

    • Author(s)
      Nakada S, Tai I, Panier S, Al-Hakim A, Iemura S, Juang YC, O'Donnell L, Kumakubo A, Munro M, Sicheri F, Gingras AC, Natsume T, Suda T, Durocher D
    • Journal Title

      Nature

      Volume: 466(7309) Pages: 941-6

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-22130001
  • [Journal Article] Acquisition of G□ state by CD34-positive cord blood cells after bone marrow transplantation2010

    • Author(s)
      Shima H, Takubo K, Tago N, Iwasaki H, Arai F, Takahashi T, Suda T
    • Journal Title

      Exp Hematol

      Volume: 38(12) Pages: 1231-40

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-22130001
  • [Journal Article] von Hippel-Lindau protein regulates transition from the fetal to the adult circulatory system in retina2010

    • Author(s)
      Kurihara T, Kubota Y, Ozawa Y, Ta kubo K, Noda K, Simon MC, Johnson RS, Suematsu M, Tsubota K, Ishida S, Goda N, Suda T, Okano H
    • Journal Title

      Development

      Volume: 137 Pages: 1563-1571

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-22130001
  • [Journal Article] Hematopoietic Stem Cells and Their Niche2010

    • Author(s)
      Iwasaki H, Suda T
    • Journal Title

      Hematopoietic Stem Cell Biology

      Pages: 37-55

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-22130001
  • [Journal Article] Cadherin-based adhesion is a potential target for niche manipulation to protect hematopoietic stem cells in adult bone marrow2010

    • Author(s)
      Hosokawa K, Arai F, Yoshihara H, Iwasaki H, Hembree M, Yin T, Nakamura N, Gomei Y, Takubo K, Shiama H, Matsuoka S, Li L, Suda T
    • Journal Title

      Cell Stem Cell

      Volume: 6 Pages: 194-8

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-22130001
  • [Journal Article] Endothelial protein C receptor-expressing hematopoietic stem cells reside in the perisinusoidal niche in fetal liver2010

    • Author(s)
      Iwasaki H, Arai F, Kubota Y, Suda T
    • Journal Title

      Blood

      Volume: 116 Pages: 544-553

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-22130001
  • [Journal Article] TIMP-3 recruits quiescent hematopoietic stem cells into active cell cycle and expands multipotent progenitor pool2010

    • Author(s)
      Nakajima H, Ito M, Smookler DS, Shibata F, Fukuchi Y, Morikawa Y, Ikeda Y, Arai F, Suda T, Khokha R, Kitamura T
    • Journal Title

      Blood

      Volume: 116(22) Pages: 4474-82

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-22130001
  • [Journal Article] Comparative gene expression analysis of zebrafish and mammals identifies common regulators in hematopoietic stem cells2010

    • Author(s)
      Kobayashi I, Ono H, Moritomo T, Kano K, Nakanishi T, Suda T
    • Journal Title

      Blood

      Volume: 115 Pages: 1-9

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-22130001
  • [Journal Article] The Blimp1-Bcl6 axis is critical to regulate osteoclast differentiation and bone hemostasis2010

    • Author(s)
      Miyauchi Y, Ninomiya K, Miyamoto H, Sakamoto A, Iwasaki R, Hoshi H, Miyamoto K, Hao W, Yoshida S, Morioka H, Chiba K, Kato S, Tokuhisa T, Saitou M, Toyama Y, Suda T, Miyamoto T
    • Journal Title

      J Exp Med

      Volume: 207 Pages: 751-762

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-22130001
  • [Journal Article] Isolation and characterization of endosteal niche cell populations that regulate hematopoietic stem cells2010

    • Author(s)
      Nakamura Y, Arai F, Iwasaki H, Hosokawa K, Kobayashi I, Gomei Y, Matsumoto Y, Yoshihara H, Suda T
    • Journal Title

      Blood

      Volume: 116 Pages: 1422-1432

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-22130001
  • [Journal Article] Knockdown of N-cadherin suppresses the long-term engraftment of hematopoietic stem cells2010

    • Author(s)
      Hosokawa K, Arai F, Yoshihara H, Iwasaki H, Nakamura Y, Gomei Y, Suda T
    • Journal Title

      Blood

      Volume: 116 Pages: 554-563

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-22130001
  • [Journal Article] Regulation of the HIF-1alpha level is essential for hematopoietic stem cells2010

    • Author(s)
      Takubo K, Goda N, Yamada W, Iriuchishima H, Ikeda E, Kubota Y, Shima H, Johnson RS, Hirao A, Suematsu M, Suda T
    • Journal Title

      Cell Stem Cell

      Volume: 7 Pages: 391-402

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-22130001
  • [Journal Article] Complex regulation of cell-cycle inhibitors by Fbxw7 in mouse embryonic fibroblasts2010

    • Author(s)
      Masuda K, Ishikawa Y, Onoyama I, Unno M, de Alboran IM, Nakayama KI, Nakayama K
    • Journal Title

      Oncogene

      Volume: 29 Pages: 1798-1809

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-22130001
  • [Journal Article] c-MYC overexpression with loss of Ink4a/Arf transforms bone marrow stromal cells into osteosarcoma accompanied by loss of adipogenesis2010

    • Author(s)
      Shimizu T, Ishikawa T, Sugihara E, Kuninaka S, Miyamoto T, Mabuchi Y, Matsuzaki Y, Tsunoda T, Miya F, Morioka H, Nakayama R, Kobayashi E, Toyama Y, Kawai A, Ichikawa H, Hasegawa T, Okada S, Ito T, Ikeda Y, Suda T, Saya H
    • Journal Title

      Oncogene

      Volume: 29(42) Pages: 5687-99

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-22130001
  • [Journal Article] Fbxw7 acts as a critical fail-safe against premature loss of hematopoietic stem cells and development of T-ALL2008

    • Author(s)
      Matsuoka S, Oike Y, Onoyama I, Iwama A, Arai F, Takubo K, Mashimo Y, Oguro H, Nitta E, Ito K, Miyamoto K, Yoshiwara H, Hosokawa K, Nakamura Y, Gomei Y, Iwasaki H, Hayashi Y, Matsuzaki Y, Nakayama K, Ikeda Y, Hata A, Chiba S, Nakayama KI, Suda T
    • Journal Title

      Genes Dev 22

      Pages: 986-991

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16002011
  • [Journal Article] Stem cell defects in ATM-deficient undifferentiated spermatogonia through DNA damage-induced cell cycle arrest2008

    • Author(s)
      Takubo K, Ohmura M, Azuma M, Nagamatsu G, Yamada Y, Arai F, Hirao A, Suda T
    • Journal Title

      Cell Stem Cell 2

      Pages: 170-182

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16002011
  • [Journal Article] FoxO3a regulates hematopoietic homeostasis through a negative feedback pathway in conditions of stress or aging.2008

    • Author(s)
      Miyamoto K, Miyamoto T, Kato R, Yoshimura A, Motoyama N, Suda T
    • Journal Title

      Blood 112

      Pages: 4485-4493

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16002011
  • [Journal Article] Foxo3a is essential for maintenance of the hematopoietic stem cell pool2007

    • Author(s)
      Miyamoto K, Y. Araki K, Naka K, Arai F, Takubo K, Yamazaki S, Matsuoka S, Miyamoto T, Ito K, Ohmura M, Chen C, Hosokawa K, Nakauchi H, Nakayama K, Nakayama K, Harada M, Motoyama N, Suda T, Hirao A
    • Journal Title

      Cell Stem Cell 1

      Pages: 101-112

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16002011
  • [Journal Article] Thrombopoietin/Mpl signaling regulates hematopoietic stem cell quiescence and interaction with the osteoblastic niche2007

    • Author(s)
      Yoshihara H, Arai F, Hosokawa K, Hagiwara T, Takubo K, Nakamura Y, Gomei Y, Iwasaki H, Matsuoka S, Miyazaki H, Takahashi T, Suda T
    • Journal Title

      Cell Stem Cell 1

      Pages: 685-697

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16002011
  • [Journal Article] Reactive oxygen species induce chondrocyte hypertrophy in endochondral ossification.2007

    • Author(s)
      Morita K, Miyamoto T, Fujita N, Kubota Y, Ito K, Takubo K, Miyamoto K, Ninomiya K, Suzuki T, Iwasaki R, Yagi M, Takaishi H, Toyama Y, Suda T
    • Journal Title

      J Exp Med 204

      Pages: 1613-1623

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16002011
  • [Journal Article] Successful reconstruction of human endometrium from singly dispersed endometrial cells in the severe immunodeficient mouse: its potenital application as endometriosis model.2007

    • Author(s)
      Masuda H, et. al.
    • Journal Title

      Proc. Natl. Acad. Sci. USA. 104

      Pages: 1925-30

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-14081101
  • [Journal Article] Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells.2006

    • Author(s)
      Ito K, Hirao A, Arai F, Takubo K, Matsuoka S, Miyamoto K, Ohmura M, Naka K, Hosokawa K, Ikeda Y, Suda T
    • Journal Title

      Nature Med 12

      Pages: 446-451

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16002011
  • [Journal Article] DC-STAMP is essential for cell-cell fusion in osteoclasts and foreign body giant cells.2005

    • Author(s)
      Yagi M, Miyamoto T, Sawatani Y, Iwamoto K, Hosogane N, Fujita N, Morita K, Ninomiya K, Suzuki T, Miyamoto K, Oike Y, Takeya M, Toyama Y, Suda T
    • Journal Title

      J Exp Med 203

      Pages: 345-351

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16002011
  • [Journal Article] Angiopoietin-1 promotes LYVE-1-positive lymphatic formation.2005

    • Author(s)
      Morisada T, Oike Y, Yamada Y, Urano T, Akao M, Kubota Y, Kimura Y, Ohmura M, Miyamoto T, Nozawa S, Koh GY, Alitalo K Suda T
    • Journal Title

      Blood (Maekawa H )[Epub ahead of print]

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370306
  • [Journal Article] Angiopoietin-related growth factor antagonizes obesity and insulin resistance.2005

    • Author(s)
      Oike Y, Akao M, Yasunaga K, Yamauchi T, Morisada T, Ito Y, Urano T, Kimura Y, Kubota Y, Maekawa H, Miyamoto T, Miyata K, Matsumoto S-i, Sakai J, Nakagata N, Takeya M, Koseki H, Ogawa Y, Kadowaki T, Suda T
    • Journal Title

      Nat Med 11

      Pages: 400-408

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370306
  • [Journal Article] Oncogenic transcription factor Evi-1 regulates hematopoietic stem cell proliferation through GATA-2 expression.2005

    • Author(s)
      Yuasa H, Oike Y, Iwama A, Nishikata I, Sugiyama D, Perkins A, Mucenski ML, Suda T, Morishita K.
    • Journal Title

      EMBO J[Epub ahead of print]

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370306
  • [Journal Article] Hematopoietic stem cells and their niche.2005

    • Author(s)
      Suda T, et al.
    • Journal Title

      Trends Immunol 26

      Pages: 426-433

    • Data Source
      KAKENHI-PROJECT-16002011
  • [Journal Article] Regulation of oxidative stress by ATM is required for self-renewal of haematopoietic stem cells.2004

    • Author(s)
      Ito K, Hirao A, Arai F, Matsuoka S, Takubo K, Nakagata N, Ikeda Y, Tak W. Mak, Suda T
    • Journal Title

      Nature 431

      Pages: 997-1002

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370306
  • [Journal Article] Derivation and morphological characterization of mouse spermatogonial stem cell lines.2004

    • Author(s)
      Ogawa T, Ohmura M, Tamura Y, Kita K, Ohbo K, Suda T, Kubota Y.
    • Journal Title

      Arch Histol Cytol 67

      Pages: 297-306

    • NAID

      10014259404

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370306
  • [Journal Article] Cell adhesion to ephrinB2 is induced by EphB4 independently of its kinase activity.2004

    • Author(s)
      Sakamoto S, Zhang X-Q, Suenobu S, Ohbo K, Ogawa M, Suda T
    • Journal Title

      Biochem Biophys Res Comm 321

      Pages: 681-687

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370306
  • [Journal Article] Spatial analysis of germ stem cell development in Oct-4/EGFP transgenic mice.2004

    • Author(s)
      Ohmura M, Yoshida S, Ide Y, Nagamatsu G, Suda T, Ohbo K.
    • Journal Title

      Arch Histol Cytol 67

      Pages: 285-296

    • NAID

      10014259368

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370306
  • [Journal Article] Tie2/Angiopoietin-1 signaling regulates hematopoietic stem cell quiescence in the bone marrow niche.2004

    • Author(s)
      Arai F, Hirao A, Ohmura M, Sato H, Matsuoka S, Takubo K, Ito K, Koh GY, Suda T
    • Journal Title

      Cell 118

      Pages: 149-161

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16002011
  • [Journal Article] Regulation of oxidative stress by ATM is required for self-renewal of haematopoietic stem cells.2004

    • Author(s)
      Ito K, Hirao A, Arai F, Matsuoka S, Takubo K, Nakagata N, Ikeda Y, Tak W. Mak, Suda T
    • Journal Title

      Nature 431

      Pages: 997-1002

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16002011
  • [Journal Article] Neurogenin3 delineated the undifferentiated spermatogonia and is required for proper spermatogenesis integrity in mice.2004

    • Author(s)
      Yoshida S, Takakura N, Ohbo K, Abe K, Guillemot F, Wakabayashi J, Yamamoto M, Suda T, Nabeshima Y.
    • Journal Title

      Dev Biol 269

      Pages: 447-458

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370306
  • [Journal Article] Tie2/Angiopoietin-1 signaling regulates hematopoietic stem cell quiescence in the bone marrow niche.2004

    • Author(s)
      Arai F, Hirao A, Ohmura M, Sato H, Matsuoka S, Takubo K, Ito K, Koh GY, Suda T
    • Journal Title

      Cell 118

      Pages: 149-161

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370306
  • [Journal Article] Angiopoietin-related growth factor (AGF) promotes epidermal proliferation, remodeling, and regeneration.2003

    • Author(s)
      Oike Y, Yasunaga K, Ito Y, Matsumoto S-i, Maekawa H, Morisada T, Arai F, Nakagata N, Takeya M, Koseki A, Masuho Y, Suda T
    • Journal Title

      Proc Natl Acad Sci USA 100

      Pages: 9494-9499

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370306
  • [Journal Article] Identification and characterization of stem cells in prepubertal spermatogogenesis in mice.2003

    • Author(s)
      Ohbo K, Yoshida S, Ohmura M, Ohneda O, Ogawa T, Tsuchiya H, Kuwana T, Kehler J, Abe K, Scholer HR, Suda T
    • Journal Title

      Dev Biol 258

      Pages: 209-225

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370306
  • [Journal Article] Expression and function of NJ-1 surface antigen in megakaryopoiesis.2002

    • Author(s)
      Tang H, Zhang X-Q, Naruse T, Ohbo K, Suda T
    • Journal Title

      Biochem Biophys Res Comm 292

      Pages: 667-674

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370306
  • [Journal Article] Mesenchymal stem cells in perichondrium express activated leukocyte cell adhesion molecule and participate in bone marrow formation.2002

    • Author(s)
      Arai F, Ohneda O, Miyamoto T, Zhang X-Q, Suda T
    • Journal Title

      J Exp Med 195

      Pages: 1549-1563

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370306
  • [Journal Article] Bone marrow-derived cells serve as pro-angiogenic macrophages but not endothelial cells in wound healing

    • Author(s)
      Okuno Y, Kishi K, Suda T, Kubota Y
    • Journal Title

      Blood

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-22130001
  • [Journal Article] A germ cell specific gene, Prmt5 works as somatic cell reprogramming

    • Author(s)
      Nagamatsu G, Kosaka T, Kawasumi M, Kinoshita T, Takubo K, Akiyama H, Sudo T, Kobayashi T, Oya M, Suda T
    • Journal Title

      J Biol.Chem

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-22130001
  • [Journal Article] Ataxia-telangiectasia mutated (ATM) deficiency decreases reprogramming efficiency and leads to genomic instability in iPS cells

    • Author(s)
      Kinoshita T, Nagamatsu G, Kosaka T, Takubo K, Hotta A, Ellis J, Suda T
    • Journal Title

      Biochem Biophys Res Commun

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-22130001
  • [Journal Article] Telomerase reverse transcriptase protects ATM-deficient hematopoietic stem cells from ROS-induced apoptosis through a telomere independent mechanism

    • Author(s)
      Nitta E, Yamashita M, Hosokawa K, Xian M, Takubo K, Arai F, Nakada S, Suda T
    • Journal Title

      Blood

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-22130001
  • [Patent] 抗がん剤の効果増強剤2012

    • Inventor(s)
      齊藤秀, 小坂威雄, 永松剛, 堀本勝久, 大家基嗣, 須田年生
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2012-127405
    • Filing Date
      2012-06-04
    • Data Source
      KAKENHI-PROJECT-23249053
  • [Presentation] Self-renewal division of HSCs in embryonal and adult stage2023

    • Author(s)
      Toshio Suda
    • Organizer
      Normal/Malignant Hematopoiesis and Novel Therapies for Hematologic Malignancies US-Japan Symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H05284
  • [Presentation] Self-renewal capacity in hematopoietic stem cells2023

    • Author(s)
      Toshio Suda
    • Organizer
      4th Scientific Workshop: The Haematological Tumor Microenvironment and its therapeutic targeting
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H05284
  • [Presentation] Self-Renewal or Differentiation in Stem Cells?2022

    • Author(s)
      Toshio Suda
    • Organizer
      N2CR Thematic Seminar
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H05284
  • [Presentation] Thrombopoietin as an expansion factor for hematopoietic stem cells2022

    • Author(s)
      Toshio Suda
    • Organizer
      International Conference of Korean Society of Hematology, 63rd Annual Meeting
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H05284
  • [Presentation] Cell Division and Metabolism in Hematopoietic Stem Cells2022

    • Author(s)
      Toshio Suda
    • Organizer
      KAIST Meeting
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H05284
  • [Presentation] Self-Renewal and Expansion of Hematopoietic Stem Cells2022

    • Author(s)
      Toshio Suda
    • Organizer
      Redox Week in Sendai 2022
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H05284
  • [Presentation] Decision of Self-renewal or differentiation in stem cells2022

    • Author(s)
      Toshio Suda
    • Organizer
      8th Severance Cardio-Cerebrovascular Research Cluster, Annual Symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H05284
  • [Presentation] Cell Division and Metabolism in Hematopoietic Stem Cells2022

    • Author(s)
      Toshio Suda
    • Organizer
      The 16th International Cell Therapy Conference of The Seoul National University Hospital
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H05284
  • [Presentation] Self-Renewal and Expansion of Hematopoietic Stem Cells for Blood Diseases2022

    • Author(s)
      Toshio Suda
    • Organizer
      Frontiers Cancer Science
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H05284
  • [Presentation] Self-Renewal and Expansion of Hematopoietic Stem Cells under the stress2022

    • Author(s)
      Toshio Suda
    • Organizer
      EMBO Workshop: The DNA Damage Response, Immunity and Aging
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H05284
  • [Presentation] Decision of self-renewal and differentiation in tissue stem cells2022

    • Author(s)
      Toshio Suda
    • Organizer
      The 66th Annual Scientific Meeting of the Korean Society of Cardiology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H05284
  • [Presentation] Mitochondrial metabolism and transfer in hematopoiesis2021

    • Author(s)
      Toshio Suda
    • Organizer
      JSPS Core to Core Program
    • Data Source
      KAKENHI-PROJECT-18H05284
  • [Presentation] Thrombopoietin as an expansion factor for hematopoietic stem cells.2021

    • Author(s)
      Toshio Suda
    • Organizer
      International Conference of Korean Society of Hematology (ICKSH) 2022
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H05284
  • [Presentation] Hematopoietic stem cells and their niche.2020

    • Author(s)
      Toshio Suda
    • Organizer
      AMED -Gene & Cell Therapy Symposium
    • Data Source
      KAKENHI-PROJECT-18H05284
  • [Presentation] Quiescence and Cell Metabolism in Hematopoietic Stem Cells2020

    • Author(s)
      Toshio Suda
    • Organizer
      American Society of Hematology, 2020 Donnall Thomas Lecture (Virtual)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H05284
  • [Presentation] 腎がん抑制遺伝子Folliculinの欠損はリソソーム制御転写因子TFE3の活性化を介してグリコーゲン合成を促進する2019

    • Author(s)
      遠藤充浩、馬場理也、遠藤多美枝、梅本晃正、橋本倫拓、平山明由、須田年生
    • Organizer
      第42回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-19K06693
  • [Presentation] Mitocondria Metabolism in Quiescence and Cycling Hematopoietic Stem Cells2019

    • Author(s)
      Toshio Suda
    • Organizer
      ISEH 48th Annual Scientific Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H05284
  • [Presentation] Quiescence and cell metabolism in stem cells2019

    • Author(s)
      Toshio Suda
    • Organizer
      Japan-Singapore International Skin Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H05284
  • [Presentation] Metabolic Change in Hematopoietic Stem Cells2019

    • Author(s)
      Toshio Suda
    • Organizer
      2019 US-Japan Symposium on Normal/Malignant Hematopoiesis and Novel Therapies for Hematologic Malignancies
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H05284
  • [Presentation] Mitocondria metabolism in HSCS2019

    • Author(s)
      Toshio Suda
    • Organizer
      16th Nikko International Symposium
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H05284
  • [Presentation] MD Mitocondria metabolism in HSCs Stem Cells2019

    • Author(s)
      Toshio Suda
    • Organizer
      Stem Cells, Aging and Stress Response Mechanisms
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H05284
  • [Presentation] Mitocondria metabolism in HSCS2019

    • Author(s)
      Toshio Suda
    • Organizer
      University of Columbia Seminar
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H05284
  • [Presentation] Purine metabolism in the divisions of hematopoietic stem cells2018

    • Author(s)
      Toshio Suda
    • Organizer
      KVBM-IBS Conference on Vascular Biology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H05284
  • [Presentation] 造血幹細胞とその微小環境2018

    • Author(s)
      須田年生
    • Organizer
      第62回日本リウマチ学会総会・学術集会
    • Data Source
      KAKENHI-PROJECT-18H05284
  • [Presentation] Protection of DNA damage in hematopoietic stem cells2018

    • Author(s)
      Toshio Suda
    • Organizer
      Hematopoietic stem cells X
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H05284
  • [Presentation] Scientific committee session Purine metabolism in the divisions of hematopoietic stem cells2018

    • Author(s)
      Toshio Suda
    • Organizer
      61st ASH Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H05284
  • [Presentation] Metabolic Change in Hematopoietic Stem Cells under Stress2018

    • Author(s)
      Toshio Suda
    • Organizer
      JSPS&NUS Joint 2 nd Symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26221309
  • [Presentation] Metabolic Regulation of Stem Cell Function2018

    • Author(s)
      Toshio Suda
    • Organizer
      Seminar in Lund University
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H05284
  • [Presentation] Metabolic Regulation of Stem Cell Function2018

    • Author(s)
      Toshio Suda
    • Organizer
      23rd Congress of EHA
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H05284
  • [Presentation] FLCN-TFE3 Feedback Loop Prevents Lysosomal Storage and BHD Tumorigenesis2018

    • Author(s)
      Mitsuhiro Endoh, Masaya Baba, Tamie Endoh, Ayako Ishizu, Toshio Suda
    • Organizer
      FRONTIERS IN CANCER SCIENCE 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K07372
  • [Presentation] Stem Cell Metabolism2017

    • Author(s)
      Toshio Suda
    • Organizer
      AMED Interstellar Symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26221309
  • [Presentation] Mitochondria Metabolism in HSCs and Niche2017

    • Author(s)
      Toshio Suda
    • Organizer
      3 rd STEM CELL SYMPOSIUM Metabolism &amp; Epigenetics
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26221309
  • [Presentation] Mitochondria metabolism in HSCs and niche2017

    • Author(s)
      Toshio Suda
    • Organizer
      US-Japan Symposium on Normal/Malignant Hematopoiesis and Novel Therapies
    • Place of Presentation
      Hawaii
    • Year and Date
      2017-02-21
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26221309
  • [Presentation] Mitochondrial Metabolism under Stress Hematopoiesis2017

    • Author(s)
      Toshio Suda
    • Organizer
      Seminar in Cambridge
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26221309
  • [Presentation] Loss of FLCN induces activation of hemophagocytic macrophages through the GABARAP-associated autophagy-lysosome process2017

    • Author(s)
      Mitsuhiro Endoh, Masaya Baba, Tamie Endoh, Yang Chong, Toshio Suda
    • Organizer
      Frontiers in Cancer Science (FCS) 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K07372
  • [Presentation] The FLCN-TFE3 axis regulates macrophage activation through cellular metabolism2017

    • Author(s)
      Mitsuhiro Endoh, Masaya Baba, Yong-Mei Guo, Terumasa Umemoto, Michihiro Hashimoto, Naoto Takahashi, Ken-ichi Sawada, Laura S. Schmidt, Toshio Suda
    • Organizer
      International Society for Experimental Hematology (ISEH) 46th Annual Scientific Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K07372
  • [Presentation] Mitochondria Metabolism in HSCs and Niche2017

    • Author(s)
      Toshio Suda
    • Organizer
      EMBO Conference: Advances in Stem Cells and Regenerative Medicine
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26221309
  • [Presentation] Hematopoietic stem cell aging2016

    • Author(s)
      Toshio Suda
    • Organizer
      1st International symposium on stem cells, aging, and disease
    • Place of Presentation
      Tokyo
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26221309
  • [Presentation] Stem Cell Metabolism in Steady-State and Stress Hematopoiesis2016

    • Author(s)
      Toshio Suda
    • Organizer
      ISRASTEM and ISCS Joint Annual Meeting
    • Place of Presentation
      Tel Aviv
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26221309
  • [Presentation] Metabolic interaction of hematopoietic stem cells with niche cells2016

    • Author(s)
      Toshio Suda
    • Organizer
      The 5th International Forum on stem cells.
    • Place of Presentation
      Tianjin
    • Year and Date
      2016-10-28
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26221309
  • [Presentation] Cell Metabolism of HSCs and their niches2016

    • Author(s)
      Toshio Suda
    • Organizer
      EMBL conference
    • Place of Presentation
      Heidelberg
    • Year and Date
      2016-06-03
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26221309
  • [Presentation] ポリコーム群 PCGF6-PRC1複合体は生殖細胞系列遺伝子の抑制を介して胚性幹細胞の未熟な分化を抑制する2016

    • Author(s)
      遠藤 充浩、遠藤 高帆、林 克彦、須田 年生、古関 明彦
    • Organizer
      第39回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2016-12-01
    • Data Source
      KAKENHI-PROJECT-16K07372
  • [Presentation] Metabolic exchange between stem cells and niche cells.2016

    • Author(s)
      Toshio Suda
    • Organizer
      Metabolism and CancerPalavas-les-Flots
    • Place of Presentation
      France
    • Year and Date
      2016-09-22
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26221309
  • [Presentation] Metabolic exchange between stem cells and niche cells.2016

    • Author(s)
      Toshio Suda
    • Organizer
      The forty-seventh international symposium of the Princess Takamatsu cancer research fund.
    • Place of Presentation
      Tokyo
    • Year and Date
      2016-11-08
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26221309
  • [Presentation] Metabolic exchange between stem cells and niche cells.2016

    • Author(s)
      Toshio Suda
    • Organizer
      39th Annual Meeting Molecular Biology Society of Japan (MBSJ)
    • Place of Presentation
      Yokohama
    • Year and Date
      2016-12-01
    • Invited
    • Data Source
      KAKENHI-PROJECT-26221309
  • [Presentation] Hematopoietic stem cells.2016

    • Author(s)
      Toshio Suda
    • Organizer
      DKFZ Mini-symposium
    • Place of Presentation
      Heidelberg
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26221309
  • [Presentation] Metabolome in stem cells2016

    • Author(s)
      Toshio Suda
    • Organizer
      SGCC 9th Annual Scientific Meeting
    • Place of Presentation
      Singapore
    • Year and Date
      2016-07-20
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26221309
  • [Presentation] Metabolism and ageing of HSCs2015

    • Author(s)
      須田 年生
    • Organizer
      SystemAge: Annual General Assembly & Midterm Review Meeting
    • Place of Presentation
      EMBL Heidelberg
    • Year and Date
      2015-05-27
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26221309
  • [Presentation] Aspp1欠損による造血幹細胞の増幅とDNA損傷蓄積による白血病化2015

    • Author(s)
      須田 年生
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2015-10-08
    • Invited
    • Data Source
      KAKENHI-PROJECT-26221309
  • [Presentation] The niche concept2015

    • Author(s)
      須田 年生
    • Organizer
      ESH International Conference
    • Place of Presentation
      Lisbon Marriott Hotel
    • Year and Date
      2015-05-07
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26221309
  • [Presentation] Hypoxic metabolism in hematopoietic stem cell2015

    • Author(s)
      須田 年生
    • Organizer
      ConsEPOC International Meeting
    • Place of Presentation
      Universidad Autonoma de Madrid
    • Year and Date
      2015-05-04
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26221309
  • [Presentation] Hematopoietic stem cells in the hypoxic niche2014

    • Author(s)
      Suda T
    • Organizer
      Keystone Symposia conference 2014 : Sensing and Signaling of Hypoxia: Interfaces with Biology and Medicine
    • Place of Presentation
      Breckenridge, Colorado, USA
    • Data Source
      KAKENHI-PROJECT-23249053
  • [Presentation] Hematopoietic stem cells in the hypoxic niche.2014

    • Author(s)
      Suda T
    • Organizer
      Keystone Symposia
    • Place of Presentation
      Breckenridge, Colorado, USA
    • Invited
    • Data Source
      KAKENHI-PLANNED-22130004
  • [Presentation] Hematopoietic stem cells in the hypoxic niche.2014

    • Author(s)
      Suda T
    • Organizer
      Keystone Symposia
    • Place of Presentation
      Breckenridge, Colorado, USA
    • Invited
    • Data Source
      KAKENHI-PROJECT-23249053
  • [Presentation] Hematopoietic stem cells in the hypoxic niche2014

    • Author(s)
      Toshio Suda
    • Organizer
      Keystone Symposia conference 2014: Sensing and Signaling of Hypoxia: Interfaces with Biology and Medicine
    • Place of Presentation
      Colorado, USA
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-22130001
  • [Presentation] Hematopoietic stem cells in the hypoxic niches.2013

    • Author(s)
      Suda T
    • Organizer
      The Hemato-Vascular System: Development and Disease
    • Place of Presentation
      Baeza, Spain
    • Invited
    • Data Source
      KAKENHI-PLANNED-22130004
  • [Presentation] Hematopoiesis under the stress.2013

    • Author(s)
      Suda T
    • Organizer
      Collaborative Meeting of the European and the Spanish Societies for Gene and Cell Therapy Palacio Municipal de Congresos
    • Place of Presentation
      Madrid, Spain
    • Data Source
      KAKENHI-PROJECT-23249053
  • [Presentation] A metabolic guide to stem cell homeostasis2013

    • Author(s)
      Suda T
    • Organizer
      Keystone Symposia: Hematopoiesis
    • Place of Presentation
      Steamboat Springs, USA
    • Year and Date
      2013-01-14
    • Invited
    • Data Source
      KAKENHI-PLANNED-22130004
  • [Presentation] Niche regulation for hematopoietic stem cells.2013

    • Author(s)
      Suda T
    • Organizer
      The Bone Marrow Niche, Stem Cells, and Leukemia: Impact of Drugs, Chemicals, and the Environment
    • Place of Presentation
      NY, USA
    • Invited
    • Data Source
      KAKENHI-PLANNED-22130004
  • [Presentation] Niche regulation for hematopoietic stem cells.2013

    • Author(s)
      Suda T
    • Organizer
      2013 Beijing International Workshop on Developmental Hematopoiesis
    • Place of Presentation
      Beijing, China
    • Invited
    • Data Source
      KAKENHI-PLANNED-22130004
  • [Presentation] Niche regulation for hematopoietic stem cells.2013

    • Author(s)
      Suda T
    • Organizer
      1st Shanghai International Workshop on Stem Cells in Cancer
    • Place of Presentation
      Shanghai, China
    • Invited
    • Data Source
      KAKENHI-PLANNED-22130004
  • [Presentation] Hematopoiesis under the stress.2013

    • Author(s)
      Suda T
    • Organizer
      Collaborative Meeting of the European and the Spanish Societies for Gene and Cell Therapy Palacio Municipal de Congresos
    • Place of Presentation
      Madrid, Spain
    • Invited
    • Data Source
      KAKENHI-PLANNED-22130004
  • [Presentation] Hematopoietic stem cells in the hypoxic niches.2013

    • Author(s)
      Suda T
    • Organizer
      The Hemato-Vascular System: Development and Disease
    • Place of Presentation
      Baeza, Spain
    • Invited
    • Data Source
      KAKENHI-PROJECT-23249053
  • [Presentation] Niche regulation for hematopoietic stem cells.2013

    • Author(s)
      Suda T
    • Organizer
      2013 Beijing International Workshop on Developmental Hematopoiesis
    • Place of Presentation
      Beijing, China
    • Invited
    • Data Source
      KAKENHI-PROJECT-23249053
  • [Presentation] A metabolic guide to stem cell homeostasis2013

    • Author(s)
      Suda T
    • Organizer
      Keystone Symposia : Hematopoiesis
    • Place of Presentation
      Steamboat Springs, USA
    • Data Source
      KAKENHI-PROJECT-23249053
  • [Presentation] A metabolic guide to stem cell homeostasis.2013

    • Author(s)
      Suda T
    • Organizer
      Keystone Symposia: Hematopoiesis
    • Place of Presentation
      Steamboat Springs, USA
    • Invited
    • Data Source
      KAKENHI-PROJECT-23249053
  • [Presentation] Niche regulation for hematopoietic stem cells2013

    • Author(s)
      Toshio Suda
    • Organizer
      1st Shanghai International Workshop on Stem Cells in Cancer
    • Place of Presentation
      Shanghai, China
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-22130001
  • [Presentation] Hematopoiesis under the stress2013

    • Author(s)
      Toshio Suda
    • Organizer
      Collaborative Meeting of the European and the Spanish Societies for Gene and Cell Therapy
    • Place of Presentation
      Madrid, Spain
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-22130001
  • [Presentation] Hematopoiesis under the stress.2013

    • Author(s)
      Suda T
    • Organizer
      USA-Japan Cooperative Cancer Workshop
    • Place of Presentation
      Maui, USA
    • Invited
    • Data Source
      KAKENHI-PROJECT-23249053
  • [Presentation] Hematopoiesis under the stress.2013

    • Author(s)
      Suda T
    • Organizer
      USA-Japan Cooperative Cancer Workshop
    • Place of Presentation
      Maui, USA
    • Year and Date
      2013-03-24
    • Invited
    • Data Source
      KAKENHI-PLANNED-22130004
  • [Presentation] Niche regulation for hematopoietic stem cells.2013

    • Author(s)
      Suda T
    • Organizer
      The Bone Marrow Niche, Stem Cells, and Leukemia: Impact of Drugs, Chemicals, and the Environment
    • Place of Presentation
      NY, USA
    • Invited
    • Data Source
      KAKENHI-PROJECT-23249053
  • [Presentation] Hematopoiesis under the stress2013

    • Author(s)
      Suda T
    • Organizer
      Collaborative Meeting of the European and the Spanish Societies for Gene and Cell Therapy Palacio Municipal de Congresos
    • Place of Presentation
      Madrid, Spain
    • Data Source
      KAKENHI-PROJECT-23249053
  • [Presentation] Niche regulation for hematopoietic stem cells.2013

    • Author(s)
      Suda T
    • Organizer
      1st Shanghai International Workshop on Stem Cells in Cancer
    • Place of Presentation
      Shanghai, China
    • Invited
    • Data Source
      KAKENHI-PROJECT-23249053
  • [Presentation] Glycolytic metabolism in hematopoietic stem cells.2012

    • Author(s)
      Suda T
    • Organizer
      ICCSR 10th Annual Meeting
    • Place of Presentation
      Yokohama, Japan
    • Year and Date
      2012-06-13
    • Invited
    • Data Source
      KAKENHI-PLANNED-22130004
  • [Presentation] Hematopoietic stem cells in the hypoxic niche.2012

    • Author(s)
      Suda T
    • Organizer
      The 17th International Vascular Biology Meeting
    • Place of Presentation
      Wiesbaden, Germany
    • Invited
    • Data Source
      KAKENHI-PROJECT-23249053
  • [Presentation] Metabolic regulation of HSCs during stress.2012

    • Author(s)
      Suda T
    • Organizer
      Stem Cells and Metabolism Conference
    • Place of Presentation
      La Jolla, USA
    • Invited
    • Data Source
      KAKENHI-PROJECT-23249053
  • [Presentation] Normal and abnormal niches for hematopoietic stem cells.2012

    • Author(s)
      Suda T
    • Organizer
      The 8th Annual Meeting of Korean Society for Stem Cell research
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2012-08-30
    • Invited
    • Data Source
      KAKENHI-PLANNED-22130004
  • [Presentation] Hematopoietic stem cell metabolism2012

    • Author(s)
      Suda T
    • Organizer
      Keystone Symposia on Molecular and Cellular Biology, The life of a Stem Cell : From Birth to Death
    • Place of Presentation
      Olympic Valley, USA
    • Year and Date
      2012-03-14
    • Data Source
      KAKENHI-PLANNED-22130004
  • [Presentation] Hematopoietic stem cells in the hypoxic niche.2012

    • Author(s)
      Suda T
    • Organizer
      The 17th International Vascular Biology Meeting
    • Place of Presentation
      Wiesbaden, Germany
    • Year and Date
      2012-06-02
    • Invited
    • Data Source
      KAKENHI-PLANNED-22130004
  • [Presentation] The endosteal stem cell niche.2012

    • Author(s)
      Suda T
    • Organizer
      ESH-EHA Scientific Workshop: Anti-Inflammatory Immune Modulatory Properties of MSCs
    • Place of Presentation
      Cannes, France
    • Year and Date
      2012-04-20
    • Invited
    • Data Source
      KAKENHI-PLANNED-22130004
  • [Presentation] Regulation of hematopietic stem cells.2012

    • Author(s)
      Suda T
    • Organizer
      Nobel Conference ”Hematopoietic Stem Cells: From Basic to Regenerative Medicine”
    • Place of Presentation
      Stockholm, Sweden
    • Invited
    • Data Source
      KAKENHI-PROJECT-23249053
  • [Presentation] Hematopoietic stem cell metabolism2012

    • Author(s)
      Suda T
    • Organizer
      Keystone Symposia on Molecular and Cellular Biology, The life of a Stem Cell : From Birth to Death
    • Place of Presentation
      Olympic Valley, USA
    • Year and Date
      2012-03-14
    • Data Source
      KAKENHI-PROJECT-23249053
  • [Presentation] Metabolic regulation of HSCs during stress.2012

    • Author(s)
      Suda T
    • Organizer
      Stem Cells and Metabolism Conference
    • Place of Presentation
      La Jolla, USA
    • Year and Date
      2012-11-05
    • Invited
    • Data Source
      KAKENHI-PLANNED-22130004
  • [Presentation] Metabolic regulation of hematopoietic stem cells during stress.2012

    • Author(s)
      Suda T
    • Organizer
      54th ASH Annual Meeting and Exposition
    • Place of Presentation
      Atlanta, USA
    • Year and Date
      2012-12-08
    • Invited
    • Data Source
      KAKENHI-PLANNED-22130004
  • [Presentation] Hematopoietic stem cellmetabolism, Keystone Symposia on Molecular and Cellular Biology2012

    • Author(s)
      Suda T
    • Organizer
      The life of a Stem Cell : From Birth to Death
    • Place of Presentation
      Olympic Valley, USA
    • Data Source
      KAKENHI-PROJECT-23249053
  • [Presentation] The endosteal stem cell niche.2012

    • Author(s)
      Suda T
    • Organizer
      ESH-EHA Scientific Workshop: Anti-Inflammatory & Immune Modulatory Properties of MSCs
    • Place of Presentation
      Cannes, France
    • Invited
    • Data Source
      KAKENHI-PROJECT-23249053
  • [Presentation] Hematopoietic stem cells in hypoxic niches2012

    • Author(s)
      Suda T
    • Organizer
      The 2012 Einstein Stem Cell Institute Symposium
    • Place of Presentation
      NY, USA
    • Year and Date
      2012-09-14
    • Data Source
      KAKENHI-PROJECT-23249053
  • [Presentation] Normal and abnormal niches for hematopoietic stem cells.2012

    • Author(s)
      Suda T
    • Organizer
      The 8th Annual Meeting of Korean Society for Stem Cell research
    • Place of Presentation
      Seoul, Korea
    • Invited
    • Data Source
      KAKENHI-PROJECT-23249053
  • [Presentation] Metabolic regulation of hematopoietic stem cells during stress2012

    • Author(s)
      Suda T
    • Organizer
      Metabolic regulation of hematopoietic stem cells during stress
    • Place of Presentation
      Atlanta, USA
    • Data Source
      KAKENHI-PROJECT-23249053
  • [Presentation] Metabolic regulation of hematopoietic stem cells during stress.2012

    • Author(s)
      Suda T
    • Organizer
      54th ASH Annual Meeting and Exposition
    • Place of Presentation
      Atlanta, USA
    • Invited
    • Data Source
      KAKENHI-PROJECT-23249053
  • [Presentation] Hematopoietic stem cell metabolism2012

    • Author(s)
      Suda T
    • Organizer
      Keystone Symposia on Molecular and Cellular Biology, The life of a Stem Cell : From Birth to Death
    • Place of Presentation
      Olympic Valley, USA(招待講演)
    • Year and Date
      2012-03-14
    • Data Source
      KAKENHI-ORGANIZER-22130001
  • [Presentation] Regulation of hematopietic stem cells.2012

    • Author(s)
      Suda T
    • Organizer
      Nobel Conference ”Hematopoietic Stem Cells: From Basic to Regenerative Medicine”
    • Place of Presentation
      Stockholm, Sweden
    • Year and Date
      2012-06-18
    • Invited
    • Data Source
      KAKENHI-PLANNED-22130004
  • [Presentation] Glycolytic metabolism in hematopoietic stem cells.2012

    • Author(s)
      Suda T
    • Organizer
      ICCSR 10th Annual Meeting
    • Place of Presentation
      Yokohama, Japan
    • Data Source
      KAKENHI-PROJECT-23249053
  • [Presentation] Regulation of quiescent hematopoietic stem cells2011

    • Author(s)
      Suda T
    • Organizer
      Heidelberg-Kyoto Joint Symposium "Crossing Boundaries : Stem Cells, Materials, and Mesoscopic Sciences"
    • Place of Presentation
      Heidelberg, Germany
    • Year and Date
      2011-07-22
    • Data Source
      KAKENHI-PLANNED-22130004
  • [Presentation] Normal haematopoietic stem cells and the stem cell niche2011

    • Author(s)
      Suda T
    • Organizer
      The 11^<th> International Symposium on Myelodysplastic Syndromes
    • Place of Presentation
      Edinburgh, UK
    • Year and Date
      2011-05-19
    • Data Source
      KAKENHI-PROJECT-23249053
  • [Presentation] Glycolytic metabolism of hematopoietic stem cells2011

    • Author(s)
      Suda T
    • Organizer
      2011 Cold Spring Harbor Asia Conference : Cellular Programs and Reprogramming
    • Place of Presentation
      Suzhou, China
    • Year and Date
      2011-10-26
    • Data Source
      KAKENHI-PLANNED-22130004
  • [Presentation] Regulation of quiescent hematopoietic stem cells2011

    • Author(s)
      Suda T
    • Organizer
      Heidelberg-Kyoto Joint Symposium "Crossing Boundaries : Stem Cells, Materials, and Mesoscopic Sciences"
    • Place of Presentation
      Heidelberg, Germany(招待講演)
    • Year and Date
      2011-07-22
    • Data Source
      KAKENHI-ORGANIZER-22130001
  • [Presentation] Regulation of quiescent hematopoietic stem cells2011

    • Author(s)
      Suda T
    • Organizer
      ISEH 40^<th> Annual Scientific Meeting
    • Place of Presentation
      Vancouver, Canada
    • Year and Date
      2011-08-27
    • Data Source
      KAKENHI-PROJECT-23249053
  • [Presentation] Hypoxic niche for hematopoietic stem cells and cancer stem cells2011

    • Author(s)
      Suda T
    • Organizer
      The 52nd Spring Meeting of the Korean Society of Hematology
    • Place of Presentation
      Seoul, Korea(招待講演)
    • Year and Date
      2011-05-27
    • Data Source
      KAKENHI-ORGANIZER-22130001
  • [Presentation] Regulation of quiescent hematopoietic stem cells2011

    • Author(s)
      Suda T
    • Organizer
      Heidelberg-Kyoto Joint Symposium "Crossing Boundaries : Stem Cells, Materials, and Mesoscopic Sciences"
    • Place of Presentation
      Heidelberg, Germany
    • Year and Date
      2011-07-22
    • Data Source
      KAKENHI-PROJECT-23249053
  • [Presentation] Regulation of quiescent hematopoietic stem cells2011

    • Author(s)
      Suda T
    • Organizer
      ISEH 40th Annual Scientific Meeting
    • Place of Presentation
      Vancouver, Canada
    • Data Source
      KAKENHI-PROJECT-23249053
  • [Presentation] Normal haematopoietic stem cells and the stem cell niche2011

    • Author(s)
      Suda T
    • Organizer
      The 11^<th> International Symposium on Myelodysplastic Syndromes
    • Place of Presentation
      Edinburgh, UK
    • Year and Date
      2011-05-19
    • Data Source
      KAKENHI-PLANNED-22130004
  • [Presentation] Niche for hematopoietic stem cells in bone marrow2011

    • Author(s)
      Suda T
    • Organizer
      The 2^<nd> Pacific Meeting for Angiogenesis and Lymphangiogenesis
    • Place of Presentation
      Jeju, Korea
    • Year and Date
      2011-10-30
    • Data Source
      KAKENHI-PLANNED-22130004
  • [Presentation] Quiescence of stem cells in the hypoxic niche.2011

    • Author(s)
      Suda T, Takubo K
    • Organizer
      Gordon Research Conferences on Stem Cells & Cancer
    • Place of Presentation
      Ventura, U.S.A.
    • Data Source
      KAKENHI-PLANNED-22130004
  • [Presentation] Glycolytic metabolism of hematopoieic stem cells2011

    • Author(s)
      Suda T
    • Organizer
      The 2nd ElseKroner-Fresenius Symposium on Molecular Mechanisms of Adult Srtem Cell Aging
    • Place of Presentation
      Gunzgurg, Germany
    • Data Source
      KAKENHI-PROJECT-23249053
  • [Presentation] Normal haematopoietic stem cells and the stem cell niche2011

    • Author(s)
      Suda T
    • Organizer
      The 11^<th> International Symposium on Myelodysplastic Syndromes
    • Place of Presentation
      Edinburgh, UK(招待講演)
    • Year and Date
      2011-05-19
    • Data Source
      KAKENHI-ORGANIZER-22130001
  • [Presentation] Normal haematopoietic stem cells and the stem cell niche2011

    • Author(s)
      Suda T
    • Organizer
      The 11 th International Symposium on Myelodysplastic Syndromes
    • Place of Presentation
      Edinburgh, UK
    • Data Source
      KAKENHI-PROJECT-23249053
  • [Presentation] Niche for hematopoietic stem cells in bone marrow2011

    • Author(s)
      Suda T
    • Organizer
      The 2^<nd> Pacific Meeting for Angiogensis and Lymphangiogenesis
    • Place of Presentation
      Jeju, Korea(招待講演)
    • Year and Date
      2011-10-30
    • Data Source
      KAKENHI-ORGANIZER-22130001
  • [Presentation] Regulation of quiescent hematopoietic stem cells2011

    • Author(s)
      Suda T
    • Organizer
      ISEH 40^<th> Annual Scientific Meeting
    • Place of Presentation
      Vancouver, Canada(招待講演)
    • Year and Date
      2011-08-27
    • Data Source
      KAKENHI-ORGANIZER-22130001
  • [Presentation] Regulation of quiescent hematopoietic stem cells2011

    • Author(s)
      Suda T
    • Organizer
      ISEH 40^<th> Annual Scientific Meeting
    • Place of Presentation
      Vancouver, Canada
    • Year and Date
      2011-08-27
    • Data Source
      KAKENHI-PLANNED-22130004
  • [Presentation] Niche for hematopoietic stem cells in bone marrow2011

    • Author(s)
      Suda T
    • Organizer
      The 2^<nd> Pacific Meeting for Angiogenesis and Lymphangiogenesis
    • Place of Presentation
      Jeju, Korea
    • Year and Date
      2011-10-30
    • Data Source
      KAKENHI-PROJECT-23249053
  • [Presentation] Glycolytic metabolism of hematopoietic stem cells2011

    • Author(s)
      Suda T
    • Organizer
      2011 Cold Spring Harbor Asia Conference : Cellular Programs and Reprogramming
    • Place of Presentation
      Suzhou, China(招待講演)
    • Year and Date
      2011-10-26
    • Data Source
      KAKENHI-ORGANIZER-22130001
  • [Presentation] Glycolytic metabolism of hematopoietic stem cells2011

    • Author(s)
      Suda T
    • Organizer
      2011 Cold Spring Harbor Asia Conference : Cellular Programs and Reprogramming
    • Place of Presentation
      Suzhou, China
    • Year and Date
      2011-10-26
    • Data Source
      KAKENHI-PROJECT-23249053
  • [Presentation] Hypoxic niche for hematopoietic stem cells and cancer stem cells2011

    • Author(s)
      Suda T
    • Organizer
      The 52nd Spring Meeting of the Korean Society of Hematology
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2011-05-27
    • Data Source
      KAKENHI-PROJECT-23249053
  • [Presentation] Hypoxic niche for hematopoietic stem cells and cancer stem cells2011

    • Author(s)
      Suda T
    • Organizer
      The 52nd Spring Meeting of the Korean Society of Hematology
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2011-05-27
    • Data Source
      KAKENHI-PLANNED-22130004
  • [Presentation] Quiescent stein cells in the niche2008

    • Author(s)
      Suda T
    • Organizer
      6^<th> International Society for Stem Cell Research (ISSCR) Annual Meeting 2008
    • Place of Presentation
      Philadelphia
    • Data Source
      KAKENHI-PROJECT-16002011
  • [Presentation] Quiescent stem cells in the niche2008

    • Author(s)
      Toshio Suda
    • Organizer
      The 6th International Society for Stem Cell Research (ISSCR) Annual Meeting
    • Place of Presentation
      Philadelphia
    • Data Source
      KAKENHI-PROJECT-16002011
  • [Presentation] Hematopoietic stem cell in the hypoxic niche2008

    • Author(s)
      Suda T
    • Organizer
      Taiwan Society for Stem Cell Research (TSSCR), International Symposia on Stem Cells, Epigenetics and Develonment
    • Place of Presentation
      Taipei
    • Data Source
      KAKENHI-PROJECT-16002011
  • [Presentation] Quiescent hematopoietic stem cell in the niche2008

    • Author(s)
      Suda T
    • Organizer
      The 32^<nd> World Congress of the International Society of Hematology
    • Place of Presentation
      Bangkok
    • Data Source
      KAKENHI-PROJECT-16002011
  • [Presentation] Quiescent hematopoietic stem cells in hypoxic niche2008

    • Author(s)
      Suda T
    • Organizer
      Summer School 2008- Stem Cell Research, Mechanisms of early differentiation
    • Place of Presentation
      Barsinghausen, Germany
    • Data Source
      KAKENHI-PROJECT-16002011
  • [Presentation] Quiescence of hematopoietic stem cells regulation by ROS.2007

    • Author(s)
      Suda T
    • Organizer
      36th Annual Scientific Meeting of International Society for Experimental Hematology
    • Place of Presentation
      Hamburg
    • Year and Date
      2007-09-28
    • Data Source
      KAKENHI-PROJECT-16002011
  • [Presentation] Quiescent stem cells in the niche.2006

    • Author(s)
      Toshio Suda
    • Organizer
      The 4th ISSCR Annual Meeting
    • Place of Presentation
      Toronto
    • Data Source
      KAKENHI-PROJECT-16002011
  • [Presentation] Niche regulation of hematopoietic stem cells by ROS.2006

    • Author(s)
      Toshio Suda
    • Organizer
      Gordon Research Conferences on Oxidative Stress and Disease
    • Place of Presentation
      Ventura, California
    • Data Source
      KAKENHI-PROJECT-16002011
  • [Presentation] Tools for identifying stem cell/niche cell interactions in the mouse.2005

    • Author(s)
      Toshio Suda
    • Organizer
      AACR Workshop on Cancer Stem Cells
    • Place of Presentation
      Lansdowne, Maryland
    • Data Source
      KAKENHI-PROJECT-16002011
  • [Presentation] Hematopoietic stem cell quiescence in the bone marrow niche.2004

    • Author(s)
      Toshio Suda
    • Organizer
      ASH 46th Annual Meeting
    • Place of Presentation
      San Diego
    • Data Source
      KAKENHI-PROJECT-16002011
  • [Presentation] Niche regulation for hematopoietic stem cells.

    • Author(s)
      Suda T
    • Organizer
      The 18th International Vascular Biology Meeting
    • Place of Presentation
      Kyoto (Japan)
    • Year and Date
      2014-04-14 – 2014-04-17
    • Invited
    • Data Source
      KAKENHI-PLANNED-22130004
  • [Presentation] Metabolic control of hematopoietic stem cell function

    • Author(s)
      Suda T
    • Organizer
      EMBO Conference-Stem Cells in Cancer and Regenerative Medicine
    • Place of Presentation
      Heidelberg (Germany)
    • Year and Date
      2014-10-09 – 2014-10-12
    • Invited
    • Data Source
      KAKENHI-PROJECT-26221309
  • [Presentation] Hematopoietic stem cells and niche cells under the stress

    • Author(s)
      Suda T
    • Organizer
      ISEH 43rd Annual Scientific Meeting
    • Place of Presentation
      Montreal (Canada)
    • Year and Date
      2014-08-21 – 2014-08-23
    • Invited
    • Data Source
      KAKENHI-PROJECT-26221309
  • [Presentation] Pathways regulating stem cell homeostasis.

    • Author(s)
      Suda T
    • Organizer
      Gordon Research Conferences- Stem Cells & Cancer
    • Place of Presentation
      Ventura (USA)
    • Year and Date
      2015-02-15 – 2015-02-20
    • Invited
    • Data Source
      KAKENHI-PLANNED-22130004
  • [Presentation] Pathways regulating stem cell homeostasis

    • Author(s)
      Suda T
    • Organizer
      Gordon Research Conferences- Stem Cells & Cancer
    • Place of Presentation
      Ventura (USA)
    • Year and Date
      2015-02-15 – 2015-02-20
    • Invited
    • Data Source
      KAKENHI-PROJECT-26221309
  • [Presentation] Hematopoiesis under the stress.

    • Author(s)
      Suda T
    • Organizer
      Hematopoiesis Meeting
    • Place of Presentation
      Lund (Sweden)
    • Year and Date
      2014-04-24 – 2014-04-25
    • Invited
    • Data Source
      KAKENHI-PLANNED-22130004
  • [Presentation] Hematopoiesis under the stress

    • Author(s)
      Suda T
    • Organizer
      DiSCUSS- Cancer Stem Cells Symposium,
    • Place of Presentation
      Hannover (Germany)
    • Year and Date
      2014-10-15 – 2014-10-17
    • Invited
    • Data Source
      KAKENHI-PROJECT-26221309
  • [Presentation] Hematopoietic stem cells and niche cells under the stress.

    • Author(s)
      Suda T
    • Organizer
      ISEH 43rd Annual Scientific Meeting
    • Place of Presentation
      Montreal (Canada)
    • Year and Date
      2014-08-21 – 2014-08-24
    • Invited
    • Data Source
      KAKENHI-PLANNED-22130004
  • [Presentation] Hematopoietic stem cell niche: Hypoxia and ROS.

    • Author(s)
      Suda T
    • Organizer
      Cell Symposia- Stem Cell Energetics
    • Place of Presentation
      Berkeley (USA)
    • Year and Date
      2014-12-09 – 2014-12-11
    • Invited
    • Data Source
      KAKENHI-PLANNED-22130004
  • [Presentation] Hematopoiesis under the stress.

    • Author(s)
      Suda T
    • Organizer
      DiSCUSS- Cancer Stem Cells Symposium
    • Place of Presentation
      Hannover (Germany)
    • Year and Date
      2014-10-15 – 2014-10-17
    • Invited
    • Data Source
      KAKENHI-PLANNED-22130004
  • [Presentation] Metabolic control of hematopoietic stem cell function.

    • Author(s)
      Suda T
    • Organizer
      EMBO Conference-Stem Cells in Cancer and Regenerative Medicine-
    • Place of Presentation
      Heidelberg (Germany)
    • Year and Date
      2014-10-09 – 2014-10-12
    • Invited
    • Data Source
      KAKENHI-PLANNED-22130004
  • [Presentation] Hematopoietic stem cell niche

    • Author(s)
      Suda T
    • Organizer
      Cell Symposia- Stem Cell Energetics
    • Place of Presentation
      Berkeley (USA)
    • Year and Date
      2014-12-09 – 2014-12-11
    • Invited
    • Data Source
      KAKENHI-PROJECT-26221309
  • 1.  YAMAGUCHI Naoto (00166620)
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  • 8.  TAKAKURA Nobuyuki (80291954)
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  • 104.  横溝 智雅
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  • 105.  安田 忠仁
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  • 106.  内原 智幸
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  • 107.  多田 昇弘
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  • 111.  黒崎 知博
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  • 112.  高橋 将文
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  • 114.  唐澤 直義
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  • 115.  井上 克枝
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  • 116.  林 洋光
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  • 117.  南 敬
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  • 118.  有馬 浩太
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  • 119.  泉 大輔
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  • 120.  三宅 慧輔
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 121.  大西 紘二
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  • 122.  岡崎 章悟
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    # of Collaborated Products: 1 results
  • 123.  本田 浩章
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 124.  樗木 俊聡
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 125.  三河 拓己
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 126.  金井 昭教
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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