Itoh Susumu 伊東進

… Alternative Names

ITOH Susumu 伊東進

伊東進イトウススム

伊藤進イトウススム

Less

Researcher Number	70223154
Other IDs	https://orcid.org/0000-0002-7967-0730
External Links
Affiliation (Current)	2025: 昭和薬科大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2019 – 2021: 昭和薬科大学, 薬学部, 教授 2013 – 2016: 昭和薬科大学, 薬学部, 教授 2010 – 2011: 昭和薬科大学, 薬学部, 教授 2009: University of Tsukuba, 大学院・人間総合科学研究科, 准教授 2006: University of Tsukuba, Graduate School of Comprehensive Human Sciences, Associate Professor, 大学院人間総合科学研究科, 助教授 … More 2005: 筑波大学, 大学院・人間総合科学研究科, 助教授 1994 – 1996: 大阪大学, 薬学部, 助手 1990 – 1993: 北海道大学, 薬学部, 助手 Less
Review Section/Research Field	Principal Investigator Biological pharmacy / Basic Section 49030:Experimental pathology-related / General medical chemistry / Natural medicines / Pathological medical chemistry Except Principal Investigator Biological pharmacy / Pathological medical chemistry / Cerebral neurosurgery
Keywords	Principal Investigator Smad / TGF-beta / TGF-β / Herp2 / Id1 / CGI-128 / E2-2 / 血管新生 / がん / 1α水酸化酵素 … More / 腸管上皮幹細胞 / オルガノイド培養 / Wntシグナル / 腸管上皮細胞 / 腸管上皮 / Villin / 大腸 / 小腸 / β-カテニン / 消化管腫瘍 / TMEPAIファミリー / TGF-βシグナル / Embryonic lethality / Angiogenesis / 胎盤 / BMP / 転写因子 / 胎生死 / 薬用植物の栽培化 / 抗がん剤 / ケモタキソミー / Swertia 属植物 / 新規薬物資源の探索 / シダ類 / 薬用植物 / リンドウ科 / Swertia属植物 / トリテルペノイド / ネパール / シダ / YAP / C18orf1 / Tie2-Cre / 発がん / 細胞増殖抑制 / C180RF1 / TMEPAI / ノックアウトマウス / ビタミンD / 遺伝子診断 / カルシウム / CYP24 / フェレドキシン還元酵素 / フェレドキシン / 骨粗鬆症 / ビタミンD_3 / P450 / 転写制御 / Gal4 / Ahレセプター / チトクローム / P450 1A1 / 薬物代謝酵素 / ES細胞 / Gene targeting / CYP1A2 / チトクロームP450 … More Except Principal Investigator CYP2C / CYP2D6 / CYP1A2 / Poor metabolizer / Nuclear polyhedorosis virus / チトクロームP-450 / P-450IIIA / 肝炎 / 自己免疫性抗体 / LECラット / カルレチクリン / プロテインジスルフィドイソメラーゼ / チトクロ-ムPー450 / D-Penicillamine / Cyclosporin-A / Protein disulfide isomerase / Hepatitis / LEC rats / Autoimmune antibodies / アルコール性肝障害 / 薬物性肝障害 / Polymorphism / N-acetyltransferase / Caffeine / Cytochrome P450 / eytensive metabolizer / 薬物代謝酵素 / P-450IA2 / 遺伝的多型性 / P-450IIC / P-450IID6 / S-メフェニトイン / poor metabolizer / チトクローム P450 / 多型性 / N-アセチル転移酵素 / カフェイン / チトクロームP450 / Cytochrome P-450 / Dexamethasone / SRalpha promoter / Aflatoxin B_1 / Liver / Fetus / Pー450_<NF> / Pー450HFLa / MCFー7 / 転写調節機構 / 細胞毒性試験 / ヒト胎児肝 / 薬物代謝 / umu試験 / nuclear polyhedorosis virus / SF9細胞 / Pー450IIIA / チトクロムPー450 / デキサメタゾン / SRalphaプロモーター / アフラトキシンB_1 / 肝臓 / 胎児 / スプライソソーム / シグナル伝達研究の新展開 / JMJD6 / LUC7L3 / Smad / Alternative splicing / 内皮細胞ワクチン / metronomic treatment / low molecular weight heparin / bevacizumab / CXCR7 / SDF-1 / 光線力学療法 / Notchシグナル / siRNA / マイクロアレイ / 神経膠腫 / 腫瘍微小環境 / 抵抗性 / ケモカイン / 腫瘍内皮細胞 / 血管新生 / 膠芽腫 / cDNAクローニング / TIQ / MPTP / FMO / パーキンソン病 / メチオニンーエンケファリン / ロイシンーエンケファリン / 合成ペプチド / エンケファリン Less

Collapse of intestinal epithelial tissue and its maintenance through TGF-beta family signalPrincipal Investigator
- Principal Investigator
  
  Itoh Susumu
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  Showa Pharmaceutical University
Exploration of novel drug materials from natural products of Himalayan areaPrincipal Investigator
- Principal Investigator
  
  Itoh Susumu
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Natural medicines
- Research Institution
  Showa Pharmaceutical University
Smad-mediated spliceosome assembly and alternative splicing
- Principal Investigator
  
  SAKATA Nobuo
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Showa Pharmaceutical University
Progress of anti-angiogenic therapy for brain tumors : new modality and resolution of the resistance
- Principal Investigator
  
  TAKANO Shingo
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  University of Tsukuba
Tumorigenicity by TGF-βsignalingPrincipal Investigator
- Principal Investigator
  
  ITOH Susumu
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Showa Pharmaceutical University
  University of Tsukuba
Regulation of endothelial cell activation by TGF-β family signalingPrincipal Investigator
- Principal Investigator
  
  ITOH Susumu
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  University of Tsukuba
カルシウム欠乏疾患関連遺伝子の解析と遺伝子診断への応用・・・ビタミンD合成酵素を中心として・・・Principal Investigator
- Principal Investigator
  
  伊東進
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  Osaka University
生体内活性型ビタミンD量を調節する酵素遺伝子の構造と機能解析Principal Investigator
- Principal Investigator
  
  伊東進
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  Osaka University
P4501A1遺伝子の転写制御を司るAhレセプターの構造と機能解析・・・遺伝子診断への応用・・・・Principal Investigator
- Principal Investigator
  
  伊藤進
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  Osaka University
パーキンソン病の原因解明:脳内におけるMPTP及びその類似化合物の代謝を司る酵素系の同定及びcDNAクローニング
- Principal Investigator
  
  鎌滝哲也
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Hokkaido University
Gene targeting法を利用した薬物代謝酵素欠損マウスの作出Principal Investigator
- Principal Investigator
  
  伊東進
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  Hokkaido University
Can the Occurence of Autoantibody to Protein Disulfide Isomerase be a Marker for the Development of Hepatitis?
- Principal Investigator
  
  YOKOI Tsuyoshi
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Hokkaido University
特異自己免疫抗体の出現は劇症肝炎発生の原因か?肝炎自然発症(LEC)ラットをモデルとして
- Principal Investigator
  
  横井毅
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Hokkaido University
チトクロ-ムPー450の新しい生理的意義に関する研究ー内因性生理活性ペプチドの調節における役割ー
- Principal Investigator
  
  YOKOI Tsuyoshi
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Hokkaido University
System for the regulation of in vivo drug concentration ; Analyzes of genetic polymorphisms of drug metabolizing enzymes
- Principal Investigator
  
  KAMATAKI Tetsuya
- Project Period (FY)
  1991 – 1993
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Hokkaido University
Basic study for dunction and gene regulation of human fetal liver P-450
- Principal Investigator
  
  KAMATAKI Tetsuya
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Hokkaido University

All 2022 2021 2019 2017 2016 2015 2014 2012 2011 2010 2009 2007 2006 Other

All Journal Article Presentation Book

[Book] TGF-βファミリーシグナル抑制機構,別冊医学のあゆみ2011
- Author(s)
  伊東進
- Data Source
  KAKENHI-PROJECT-21590328
[Book] Inhibitory machinery for the TGF-β family signaling pathway. Growth Factors2011
- Author(s)
  Itoh S., Itoh F.
- Data Source
  KAKENHI-PROJECT-21590328
[Book] 別冊医学のあゆみ:TGF-βファミリーシグナル抑制機構2011
- Author(s)
  伊東進
- Total Pages
  7
- Publisher
  医学のあゆみ
- Data Source
  KAKENHI-PROJECT-21590328
[Book] TGF-βファミリーシグナル抑制機構,医学のあゆみ2010
- Author(s)
  伊東進
- Data Source
  KAKENHI-PROJECT-21590328
[Book] 血管新生におけるTGF-βファミリーの役割と疾患,実験医学2010
- Author(s)
  伊東史子、伊東進、加藤光保
- Data Source
  KAKENHI-PROJECT-21590328
[Book] 概論-TGF-βファミリー研究の新しい流れ,実験医学2010
- Author(s)
  宮澤恵二、伊東進
- Data Source
  KAKENHI-PROJECT-21590328
[Book] TGF-βファミリーシグナルとその調節機構2007
- Author(s)
  伊東進, 加藤光保
- Publisher
  ューサイエンス社(In press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390073
[Book] Negative regulation of the TGF-β family signal pathway by inhibitory Smads and their involvement in cancer and fibrosis.2007
- Author(s)
  Susumu Itoh et al.
- Publisher
  Human Press Inc., NJ(In press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390073
[Book] Negative regulation of the TGF-・family signal pathway by inhibitory Smads and their involvement in cancer and fibrosis2007
- Author(s)
  Susumu Itoh
- Publisher
  The Human Press(In press)
- Data Source
  KAKENHI-PROJECT-17390073
[Book] Negative regulation of the TGF-β family signal pathway by inhibitory Smads and their involvement in cancer and fibrosis2006
- Author(s)
  Susumu itoh
- Publisher
  The Human Press(In press)
- Data Source
  KAKENHI-PROJECT-17390073
[Journal Article] Hybrid molecule between platanic acid and LCL-161 as a yes-associated protein degrader2022
- Author(s)
  Nakano Naoko、Fukuda Kazuo、Tashiro Etsu、Ishikawa Haruka、Nagano Waka、Kawamoto Rie、Mori Alice、Watanabe Misao、Yamazaki Ryu、Nakane Takahisa、Naito Mikihiko、Okamoto Iwao、Itoh Susumu
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: - Issue: 6 Pages: 631-640
- DOI
  10.1093/jb/mvac021
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02777, KAKENHI-PROJECT-21K06975, KAKENHI-PROJECT-20K05732, KAKENHI-PLANNED-18H05502, KAKENHI-PROJECT-19H03456
[Journal Article] Endothelial-specific depletion of TGF-β signaling affects lymphatic function.2021
- Author(s)
  Kunpei Fukasawa, Kako Hanada, Kei Ichikawa, Masanori Hirashima, Takahiro Takagi, Susumu Itoh, Testuro Watabe, Fumiko Itoh.
- Journal Title
  
  Inflamm Regen .
  
  Volume: 41 Issue: 1 Pages: 35-35
- DOI
  10.1186/s41232-021-00185-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07430, KAKENHI-PROJECT-19H03456
[Journal Article] Environmental and soil characteristics in Ephedra habitats of Uzbekistan2021
- Author(s)
  Minami Motoyasu、Taichi Fujii、Honda Yukako、Ueno Kaoru、Shinozaki Junichi、Itoh Susumu、Takano Akihito、Berdiyar Jollibekov、Maltsev Ivan Ivanovich、Nakane Takahisa
- Journal Title
  
  Journal of Natural Medicines
  
  Volume: 75 Issue: 1 Pages: 246-258
- DOI
  10.1007/s11418-020-01460-3
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03456
[Journal Article] Narciclasine is a novel YAP inhibitor that disturbs interaction between YAP and TEAD42021
- Author(s)
  Rie Kawamoto, Naoko Nakano, Haruka Ishikawaa, Etsu Tashiroa, Waka Nagano, Keigo Sano, Miki Irie, Mariko Ikuta, Fukuko Kishi, Takahisa Nakane, Mikihiko Naito, Susumu Itoh
- Journal Title
  
  BBA advances
  
  Volume: 1 Pages: 100008-100008
- DOI
  10.1016/j.bbadva.2021.100008
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16360, KAKENHI-PROJECT-19H03456
[Journal Article] Involvement of miR-3180-3p and miR-4632-5p in palmitic acid-induced insulin resistance2021
- Author(s)
  Tashiro Etsu、Nagasawa Yumi、Itoh Susumu、Imoto Masaya
- Journal Title
  
  Molecular and Cellular Endocrinology
  
  Volume: 534 Pages: 111371-111371
- DOI
  10.1016/j.mce.2021.111371
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K05732, KAKENHI-PROJECT-19H03456
[Journal Article] TGF-βシグナルを抑制するTMEPAIファミリー2017
- Author(s)
  伊東　進
- Journal Title
  
  生化学
  
  Volume: 89
- NAID
  40021203141
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26305006
[Journal Article] Targeted Degradation of Proteins Localized in Subcellular Compartments by Hybrid Small Molecules.2017
- Author(s)
  Okuhira, K., Shoda, T., Omura, R., Ohoka, N., Hattori, T., Shibata, N., Demizu, Y., Sugihara, R., Ichino, A., Kawahara, H., Itoh, Y., Ishikawa, M., Hashimoto, Y., Kurihara, M., Itoh, S., Saito, H. & Naito, M.
- Journal Title
  
  Mol pharmacol
  
  Volume: 91 Issue: 3 Pages: 159-166
- DOI
  10.1124/mol.116.105569
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16H05090, KAKENHI-PROJECT-25293027, KAKENHI-PROJECT-26305006, KAKENHI-PROJECT-16K08236, KAKENHI-PROJECT-26460169, KAKENHI-PROJECT-16K15121, KAKENHI-PROJECT-16K18916, KAKENHI-PROJECT-16K08340, KAKENHI-PROJECT-17H03979
[Journal Article] TMED10 Protein Interferes with Transforming Growth Factor (TGF)-β Signaling by Disrupting TGF-β Receptor Complex Formation.2017
- Author(s)
  Nakano N, Tsuchiya Y, Kako K, Umezaki K, Sano K, Ikeno S, Otsuka E, Shigeta M, Nakagawa A, Sakata N, Itoh F, Nakano Y, Iemura SI, van Dinther M, Natsume T, Ten Dijke P, Itoh S.
- Journal Title
  
  J Biol Chem
  
  Volume: 292(10) Issue: 10 Pages: 4099-4112
- DOI
  10.1074/jbc.m116.769109
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-24115007, KAKENHI-PROJECT-26305006, KAKENHI-PROJECT-26460479
[Journal Article] Regulation of the TMEPAI promoter by TCF7L2: the C-terminal tail of TCF7L2 is essential to activate the TMEPAI gene2016
- Author(s)
  Naoko Nakano, Mitsuyasu Kato & Susumu Itoh
- Journal Title
  
  The journal of biochemistry
  
  Volume: 159 Issue: 1 Pages: 27-30
- DOI
  10.1093/jb/mvv117
- NAID
  120007129718
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K18866, KAKENHI-PROJECT-25293092, KAKENHI-PROJECT-26305006
[Journal Article] Arf6 regulates tumour angiogenesis and growth through HGF-induced endothelial β1 integrin recycling.2015
- Author(s)
  Hongu T, Funakoshi Y, Fukuhara S, Suzuki T, Sakimoto S, Takakura N, Ema M, Takahashi S, Itoh S, Kato M, Hasegawa H, Mochizuki N, Kanaho Y.
- Journal Title
  
  Nat. Commun.
  
  Volume: 6 Issue: 1 Pages: 7925-7925
- DOI
  10.1038/ncomms8925
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25430002, KAKENHI-PROJECT-26440044, KAKENHI-PROJECT-15K19001, KAKENHI-PROJECT-26220207, KAKENHI-PROJECT-15H02503, KAKENHI-PROJECT-26670107, KAKENHI-PROJECT-24300330, KAKENHI-PROJECT-25293050, KAKENHI-PROJECT-26290030, KAKENHI-PROJECT-26305006
[Journal Article] ネパール・イラム地方マイポカリ地域における薬用植物Swertia chirayita の栽培に関する現地調査2015
- Author(s)
  高野昭人，中根孝久，磯田進，Yadav P.K.，Kadel D.R.，Malla K.J.，Thapa Y.B.，伊東進
- Journal Title
  
  日本植物園協会誌
  
  Volume: 50 Pages: 55-56
- Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26305006
[Journal Article] Transforming growth factor-β signaling enhancement by long-term exposure to hypoxia in a tumor microenvironment composed of Lewis lung carcinoma cells2015
- Author(s)
  Furuta C, Miyamoto T, Takagi T, Noguchi Y, Kaneko J, Itoh S, Watanabe T, Itoh F
- Journal Title
  
  Cancer Sci
  
  Volume: 106 Issue: 11 Pages: 1524-1533
- DOI
  10.1111/cas.12773
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460659, KAKENHI-PROJECT-26305006
[Journal Article] TGF-β signaling cooperates with AT motif-binding factor-1 for repression of the α-fetoprotein promoter.2014
- Author(s)
  Nobuo Sakata, Satoshi Kaneko, Souichi Ikeno, Yutaka Miura, Hidekazu Nakabayashi, Xue-Yuan Dong, Jin-Tang Dong, Taiki Tamaki, Naoko Nakano, Susumu Itoh
- Journal Title
  
  J. Signal Transduct.
  
  Volume: 2014 Pages: 970346-970346
- DOI
  10.1155/2014/970346
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25670168, KAKENHI-PROJECT-26305006
[Journal Article] C18ORF1: A Novel Negative Regulator of TGF-β Signaling.2014
- Author(s)
  2. Nakano N, Maeyama K, Ikeno S, Itoh F, Togawa Y, Katsu Y, Thanh Thao, VN, Watanabe Y, Kato M & Itoh, S.
- Journal Title
  
  J. Biol. Chem.,
  
  Volume: 289 Issue: 18 Pages: 12680-12680
- DOI
  10.1074/jbc.m114.558981
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23689023, KAKENHI-PUBLICLY-25118728, KAKENHI-PROJECT-25293092, KAKENHI-PROJECT-25670168, KAKENHI-PROJECT-26305006, KAKENHI-PROJECT-26460479
[Journal Article] TMEPAI/PMEPA1 enhances tumorigenic activities in lung cancer cells.2014
- Author(s)
  3) Vo Nguyen TT, Watanabe Y, Shiba A, Noguchi M, Itoh S and Kato M.
- Journal Title
  
  Cancer Sci.
  
  Volume: 105 Issue: 3 Pages: 334-341
- DOI
  10.1111/cas.12355
- NAID
  120007136725
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25293092, KAKENHI-PUBLICLY-26116707, KAKENHI-PROJECT-26305006
[Journal Article] Interference of E2-2-mediated effect in endothelial cells by FAM96B through its limited expression of E2-22011
- Author(s)
  Yang W., Itoh F., Ohya H., Kishimoto F., Tanaka A., Nakano N., Itoh S., Kato M
- Journal Title
  
  Cancer Sci
  
  Volume: 102 Issue: 10 Pages: 1808-1814
- DOI
  10.1111/j.1349-7006.2011.02022.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590328, KAKENHI-PROJECT-23659146, KAKENHI-PROJECT-23689023
[Journal Article] Flk1-GFP BAC Tg Mice: An Animal Model for the Study of Blood Vessel Development2010
- Author(s)
  Ishitobi H., Matsumoto K., Azami T., Itoh F., Itoh S., Takahashi S., Ema M
- Journal Title
  
  Exp. Anim.
  
  Volume: 59 Issue: 5 Pages: 615-622
- DOI
  10.1538/expanim.59.615
- NAID
  130000419256
- ISSN
  0007-5124, 1341-1357, 1881-7122
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590328
[Journal Article] Requirement of TCF7L2 for TGF-β-dependent transcriptional activation of the TMEPAI gene2010
- Author(s)
  Nakano N, Itoh S, Watanabe Y, Maeyama K, Itoh F, Kato M
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 285 Pages: 38023-38033
- NAID
  120007137359
- URL
  http://www.jbc.org/content/285/49/38023.long
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590328
[Journal Article] 概要-TGF-βファミリー研究の新しい流れ2010
- Author(s)
  宮澤恵二、伊東進
- Journal Title
  
  実験医学
  
  Volume: 28 Pages: 850-855
- Data Source
  KAKENHI-PROJECT-21590328
[Journal Article] 血管新生におけるTGF-βファミリーの役割と疾患2010
- Author(s)
  伊東史子、伊東進、加藤光保
- Journal Title
  
  実験医学
  
  Volume: 28 Pages: 877-882
- Data Source
  KAKENHI-PROJECT-21590328
[Journal Article] TGF-βファミリーシグナルの抑制作用2010
- Author(s)
  伊東進
- Journal Title
  
  実験医学
  
  Volume: 234 Pages: 893-899
- Data Source
  KAKENHI-PROJECT-21590328
[Journal Article] TMEPAI, a transmembrane TGF-β-inducible protein, sequesters from active participation in TGF-β signaling2010
- Author(s)
  Watanabe Y., Itoh S., Goto T., Ohnishi, E., Inamitsu M., Itoh F., Satoh K., Wiercinska E., Yang W., Shi L., Tanaka A., Nakano N., Mommaas A. M., Shibuya H., ten Dijke P., Kato M
- Journal Title
  
  Mol. Cell
  
  Volume: 37 Issue: 1 Pages: 123-134
- DOI
  10.1016/j.molcel.2009.10.028
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590328
[Journal Article] Inhibition of endothelial cell activation by bHLH protein E2-2 and its impairment of angiogenesis2010
- Author(s)
  Tanaka A., Itoh F., Nishiyama K., Takezawa T., Kurihara H., Itoh S., Kato M
- Journal Title
  
  Blood
  
  Volume: 115 Issue: 20 Pages: 4138-4147
- DOI
  10.1182/blood-2009-05-223057
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590328
[Journal Article] Poor vessel formation in embryos from knock-in mice expressing ALK5 with L45 loop mutation defective in Smad activation2009
- Author(s)
  Itoh F., Itoh S., Carvalho R. L. C., Adachi T., Ema M., Goumans M.-J., Larsson J., Karlsson S., Takahashi S., Mummery C. L., ten Dijke P., Kato M
- Journal Title
  
  Lab. Invest
  
  Volume: 89 Issue: 7 Pages: 800-810
- DOI
  10.1038/labinvest.2009.37
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590328
[Journal Article] TAL1/SCL relieves the E2-2-mediated repression of VEGFR2 promoter activity2009
- Author(s)
  Tanaka A., Itoh F., Itoh S., Kato M
- Journal Title
  
  J. Biochem
  
  Volume: 145 Issue: 2 Pages: 129-135
- DOI
  10.1093/jb/mvn158
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590328
[Journal Article] Poor vessel formation in embryos from knock-in mice expressing ALK5 with L45 loop mutation defective in Smad activation.2009
- Author(s)
  Fumiko Itoh, et al
- Journal Title
  
  Laboratory Investigation 89
  
  Pages: 800-810
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590328
[Journal Article] Negative regulation of TGF-β receptor/Smad signal transduction2007
- Author(s)
  Susumu Itoh., Peter ten Dijke
- Journal Title
  
  Curr. Opin. Cell Biol. 19
  
  Pages: 176-184
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390073
[Journal Article] Negative regulation of TGF-β receptor/Smad signal transduction.2007
- Author(s)
  Susumu Itoh, Peter ten Dijke
- Journal Title
  
  Curr.Opin.Cell.Biol. 19
  
  Pages: 176-184
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390073
[Journal Article] Negative regulation of TGF-βreceptor/Smad signal transduction.2007
- Author(s)
  Susumu Itoh
- Journal Title
  
  Curr. Opin. Cell Biol. 19
  
  Pages: 176-184
- Data Source
  KAKENHI-PROJECT-17390073
[Journal Article] Negative regulation of the TGF-β family signal pathway by inhibitory Smads and their involvement in cancer and fibrosis.
- Author(s)
  Susumu Itoh et al.
- Journal Title
  
  Transforming growth factor-β in cancer therapy (ed. Jakowlew SB) (Human Press Inc. NJ) (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390073
[Journal Article] TGF-β signaling and its regulatory mechanism.
- Author(s)
  Susumu Itoh, Mitsuyasu Kato
- Journal Title
  
  The Cell (Japanese) (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390073
[Presentation] YAPシグナルを標的とした新規抗がん剤の開発2021
- Author(s)
  中野　なおこ、田代　悦、永野　和果、伊東　進
- Organizer
  第25回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03456
[Presentation] TMEPAI遺伝子ファミリー欠損マウスにおける消化管腫瘍形成抑制機構の解明2021
- Author(s)
  星名　黎、伊東　進、中野　なおこ
- Organizer
  第25回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03456
[Presentation] Intestinal tumor development in mice lacking TGFβ signal components2021
- Author(s)
  Susumu Itoh
- Organizer
  Virtual TGFβ meeting in Uppsala
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03456
[Presentation] TMEPAIファミリー分子によるマウス消化管腺腫制御分子メカニズムの解明2021
- Author(s)
  中野　なおこ、星名　黎、内田　吉美、伊東　史子、渡邊　幸秀、武藤　誠、加藤　光保、伊東　進
- Organizer
  第94回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19H03456
[Presentation] 消化管腫瘍形成におけるTMEPAI遺伝子ファミリーの役割2021
- Author(s)
  中野　なおこ、伊東　史子、渡邊　幸秀、武藤　誠、加藤　光保、伊東　進
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H03456
[Presentation] 中皮腫進展抑制を目指したSNIPER化合物の開発2021
- Author(s)
  永野　和果、内藤　幹彦、伊東　進、中野　なおこ、田代　悦
- Organizer
  第25回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03456
[Presentation] がん進展制御機構を解明し、創薬に繋げるーTGF-βシグナルとYAPシグナルに着目してー2019
- Author(s)
  伊東　進
- Organizer
  第63回日本薬学会関東支部大会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03456
[Presentation] 大腸慢性炎症誘発腫瘍モデルにおけるTGF-βシグナル抑制因子TMEPAIファミリー遺伝子欠損マウスの解析2019
- Author(s)
  伊東　真菜、石川　諒、芝崎　哲平、佐野　圭吾、伊東　進
- Organizer
  2019年度日本生化学会関東支部例会
- Data Source
  KAKENHI-PROJECT-19H03456
[Presentation] TGF-βシグナルを阻害するTMEPAI遺伝子欠損マウスにおける消化管腫瘍進展抑制2019
- Author(s)
  東理紗子、芝﨑哲平、佐野圭吾、天野翔瑛、澤田悠太郎、石川諒、伊東史子、渡邊幸秀、武藤誠、加藤光保、伊東進
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19H03456
[Presentation] マウス小腸上皮由来オルガノイド培養法の確立2019
- Author(s)
  淺利　心、山崎　航平、鈴木　香枝、佐野　圭吾、中野　なおこ、伊東　進
- Organizer
  2019年度日本生化学会関東支部例会
- Data Source
  KAKENHI-PROJECT-19H03456
[Presentation] TMED10はTGF-β受容体複合体形成を抑制しTGF-βシグナル伝達を阻害する2016
- Author(s)
  中野なおこ、土屋裕樹、加古拳朗、梅嵜乾隆、佐野圭吾、池野聡一、大塚愛理、中川愛、坂田宣夫、伊東史子、家村俊一郎、夏目徹、伊東進
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-26305006
[Presentation] 転写因子YAPを標的としたプロテインノックダウン法の確立2016
- Author(s)
  中野なおこ、服部隆行、内藤幹彦、伊東進
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県、横浜市）
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-26305006
[Presentation] Endothelial TGF-β signaling increases tumor malignancy.2016
- Author(s)
  Itoh F, Saito Y, Inagawa T, Miyamoto T, Fruttinger M, Watanabe T, Itoh S
- Organizer
  19th International Vascular Biology Meeting
- Place of Presentation
  Boston, USA
- Year and Date
  2016-10-30
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26305006
[Presentation] 血管内皮細胞特異的TGF-βファミリーシグナル欠損による血管構造異常2016
- Author(s)
  宮本樹、斎藤裕紀、高木尊大、伊東進、渡部琢也、伊東史子
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県、横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-26305006
[Presentation] 低分子化合物による網羅的人工ユビキチン化システムの構築2016
- Author(s)
  服部隆行、正田卓司、奥平桂一郎、柴田識人、大岡伸通、伊東進、栗原正明、内藤幹彦
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台国際センター（宮城県、仙台市）
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-26305006
[Presentation] 網羅的人工的ユビキチン修飾システムの構築2016
- Author(s)
  服部隆行、正田卓司、奥平桂一郎、柴田識人、大岡伸通、伊藤進、栗原正明、内藤幹彦
- Organizer
  日本薬学会第136回年会
- Place of Presentation
  パシフィコ横浜(横浜市）
- Year and Date
  2016-03-26
- Data Source
  KAKENHI-PROJECT-26305006
[Presentation] がん遺伝子YAPを標的としたプロテインノックダウン法の確立2016
- Author(s)
  中野なおこ、正田卓司、服部隆行、栗原正明、内藤幹彦、伊東進
- Organizer
  第20回日本がん分子標的治療学会学術集会
- Place of Presentation
  別府国際コンベンションセンター B-CON PLAZA （大分県、別府市）
- Year and Date
  2016-05-30
- Data Source
  KAKENHI-PROJECT-26305006
[Presentation] TGF-βシグナルによるたばこ煙含有がん原物質の代謝的活性化に関与するチトクロームP-450遺伝子発現制御メカニズムと肺がん進展抑制機構の解明2016
- Author(s)
  伊東進、中野なおこ、佐野圭吾、葛祐妃、後瀬大樹、仲西盛史
- Organizer
  喫煙科学研究財団平成27年度助成研究発表会
- Place of Presentation
  京王プラザホテル（東京都、新宿区）
- Data Source
  KAKENHI-PROJECT-26305006
[Presentation] 腫瘍リンパ行性転移におけるTGF-βシグナルの役割2016
- Author(s)
  伊東史子、稲川俊彦、渡部琢也、伊東進
- Organizer
  第40回日本リンパ学会総会
- Place of Presentation
  東京大学（東京都、文京区）
- Year and Date
  2016-06-24
- Data Source
  KAKENHI-PROJECT-26305006
[Presentation] Genetic modified analysis of TGF-β type I and Type II receptors in endothelial cells.2016
- Author(s)
  Saito Y, Inagawa T, Miyamoto T, Itoh S, Watanabe T, Itoh F
- Organizer
  The 14th Korea-Japan Joint symposium on Vascular Biology
- Place of Presentation
  長崎ブリックホール（長崎県、長崎市）
- Year and Date
  2016-12-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26305006
[Presentation] TMED10 intefers with TGFβ signaling via its extracellular domain2015
- Author(s)
  Itoh S
- Organizer
  TGF-β meeting in Uppsala 2015
- Place of Presentation
  Ludiwg Cancer Institute (Uppsala, Sweden)
- Year and Date
  2015-08-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26305006
[Presentation] ネパール・イラム地方マイポカリ地域における薬用植物Swertia chirayita の栽培に関する現地調査2015
- Author(s)
  高野昭人，中根孝久，磯田進，Yadav P.K.，Kadel D.R.，Malla K.J.，Thapa Y.B.，伊東進
- Organizer
  日本植物園協会50周年記念大会
- Place of Presentation
  国立京都国際会館（京都市）
- Year and Date
  2015-06-25
- Data Source
  KAKENHI-PROJECT-26305006
[Presentation] TMED10 dissoicates TGF-β receptor complex to inhibit TGF-β signal2015
- Author(s)
  Nakano N, Itoh F, Itoh S
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（名古屋市）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26305006
[Presentation] タバコ含有がん原物質の代謝活性化を司るチトクロームP450遺伝子のTGF-β依存的発現抑制機構と喫煙による肺がんリスク研究2014
- Author(s)
  伊東進、池野聡一、中野なおこ、大村佳織、亀田洋子、毛利幸恵
- Organizer
  第29回平成25年度公益財団法人喫煙科学研究財団助成研究発表会
- Place of Presentation
  京王プラザホテル、東京
- Year and Date
  2014-07-15
- Data Source
  KAKENHI-PROJECT-26305006
[Presentation] TMED10によるTGF-βシグナル抑制機構の解析2014
- Author(s)
  木村栄希、加古拳朗、大塚愛理、梅嵜乾隆、土屋裕樹、中野なおこ、伊東進
- Organizer
  第58回日本薬学会関東支部大会
- Place of Presentation
  昭和薬科大学、町田
- Year and Date
  2014-10-04
- Data Source
  KAKENHI-PROJECT-26305006
[Presentation] TMEPAIファミリーによるTGF-βシグナル制御機構2014
- Author(s)
  中野なおこ、赤津俊介、中田美紀、伊東史子、坂田宣夫、葛祐紀、池野聡一、戸川陽子、伊東進
- Organizer
  第58回日本薬学会関東支部会
- Place of Presentation
  昭和薬科大学（町田市）
- Year and Date
  2014-10-04
- Data Source
  KAKENHI-PROJECT-25670168
[Presentation] PDZK1IP1によるTGF-βファミリーシグナル伝達経路抑制機構2014
- Author(s)
  赤津凌介、池野聡一、竹田哲也、中野なおこ、箕輪貴司、花方信孝、伊東史子、伊東進
- Organizer
  第58回日本薬学会関東支部大会
- Place of Presentation
  昭和薬科大学、町田
- Year and Date
  2014-10-04
- Data Source
  KAKENHI-PROJECT-26305006
[Presentation] TGF-βシグナル分子欠損マウス胎仔由来線維芽細胞MEFの機能解析2014
- Author(s)
  木村真央、柴宏子、中野なおこ、伊東進
- Organizer
  第58回日本薬学会関東支部大会
- Place of Presentation
  昭和薬科大学、町田
- Year and Date
  2014-10-04
- Data Source
  KAKENHI-PROJECT-26305006
[Presentation] TGF-βによるCYP1A1遺伝子発現抑制機構2014
- Author(s)
  葛祐妃、菊間美咲、大村佳織、高橋悠太、沼生智晴、福田真弓、中野なおこ、池野聡一、伊東進
- Organizer
  第58回日本薬学会関東支部大会
- Place of Presentation
  昭和薬科大学、町田
- Year and Date
  2014-10-04
- Data Source
  KAKENHI-PROJECT-26305006
[Presentation] 転写因子ATBF1とTGF-βシグナル伝達系によるα-fetoprotein遺伝子プロモーターの協調的抑制2014
- Author(s)
  坂田宜夫、金子哲士、池野聡一、三浦裕、中林秀和、Xue-Yuan Dong、Jin-Tang Dong、玉置大器、中野なおこ、伊東進
- Organizer
  第58回日本薬学会関東支部大会
- Place of Presentation
  昭和薬科大学、町田
- Year and Date
  2014-10-04
- Data Source
  KAKENHI-PROJECT-26305006
[Presentation] 転写因子ATBF1とTGF-βシグナル伝達系によるalpha-fetoprotein遺伝子プロモーターの協調的抑制2014
- Author(s)
  坂田宣夫、金子哲士、池野聡一、三浦裕、中林秀和、Xue-Yuan Dong、Jin-Tang Dong、玉置大器、中野なおこ、伊東進
- Organizer
  第58回日本薬学会関東支部会
- Place of Presentation
  昭和薬科大学（町田市）
- Year and Date
  2014-10-04
- Data Source
  KAKENHI-PROJECT-25670168
[Presentation] TMEPAIファミリーによるTGF-βシグナル制御機構2014
- Author(s)
  中野なおこ、赤津凌介、中田美紀、伊東史子、坂田宜夫、葛祐妃、池野聡一、戸川陽子、伊東進
- Organizer
  第58回日本薬学会関東支部大会
- Place of Presentation
  昭和薬科大学、町田
- Year and Date
  2014-10-04
- Data Source
  KAKENHI-PROJECT-26305006
[Presentation] TGF-βはA549細胞においてC/EBPb及びSREBP-1の発現を誘導する2014
- Author(s)
  荻なつみ、竹本友里夏、中野なおこ、伊東進
- Organizer
  第58回日本薬学会関東支部大会
- Place of Presentation
  昭和薬科大学、町田
- Year and Date
  2014-10-04
- Data Source
  KAKENHI-PROJECT-26305006
[Presentation] Cooperative International Framework in TGF-β Family Signaling2012
- Author(s)
  Itoh S
- Organizer
  The 1^<st> International Symposium by JSPS Core-to-Core Program
- Place of Presentation
  東京大学、東京
- Year and Date
  2012-01-24
- Data Source
  KAKENHI-PROJECT-21590328
[Presentation] Role of Smad2 and Smad3 in vascular stability2012
- Author(s)
  Itoh S
- Organizer
  The 1^<st> International Symposium by JSPS Core-to-Core Program "Cooperative International Framework in TGF-b Family Signaling
- Place of Presentation
  東京大学、東京(招待講演)
- Year and Date
  2012-01-24
- Data Source
  KAKENHI-PROJECT-21590328
[Presentation] Smad2/3 signaling is required for vascular stability2011
- Author(s)
  Itoh S
- Organizer
  日蘭二国間セミナー
- Place of Presentation
  昭和薬科大学、東京
- Year and Date
  2011-11-04
- Data Source
  KAKENHI-PROJECT-21590328
[Presentation] Regulation of endothelial cell migration by FAM96B2011
- Author(s)
  Itoh S
- Organizer
  TGF-βmeeting in Uppsala
- Place of Presentation
  Uppsala, Sweden
- Year and Date
  2011-08-20
- Data Source
  KAKENHI-PROJECT-21590328
[Presentation] Smad2/3 signaling is required for vascular stability2011
- Author(s)
  Itoh S
- Organizer
  日蘭二国間セミナー
- Place of Presentation
  昭和薬科大学、町田、東京(招待講演)
- Year and Date
  2011-11-04
- Data Source
  KAKENHI-PROJECT-21590328
[Presentation] Transmembrane AR-Smad Trapper (TARST) family is a negative regulator of TGF-β signaling2011
- Author(s)
  Itoh S, Maeyama K, Nakano N, Watanabe Y, Itoh F, Togawa T, Kato M
- Organizer
  FASEB Summer Research Conference
- Place of Presentation
  Barga, Italy
- Year and Date
  2011-08-23
- Data Source
  KAKENHI-PROJECT-21590328
[Presentation] Regulation of endothelial cell migration by FAM96B2011
- Author(s)
  Itoh S
- Organizer
  TGF-β meeting in Uppsala
- Place of Presentation
  Uppsala, Sweden(招待講演)
- Year and Date
  2011-08-20
- Data Source
  KAKENHI-PROJECT-21590328
[Presentation] Transmembrane AR-Smad Trapper(TARST) family is a negative regulator of TGF-βsignaling2011
- Author(s)
  Itoh S, Maeyama K, Nakano N, Watanabe Y, Itoh F, Togawa T and Kato M
- Organizer
  FASEB Summer Research Conference
- Place of Presentation
  Barga, Italy
- Year and Date
  2011-08-23
- Data Source
  KAKENHI-PROJECT-21590328
[Presentation] Negative regulation of TGF-β signaling by TMEPAI and its possible involvement for tumorigenicity2010
- Author(s)
  Susumu Itoh
- Organizer
  BMB2010
- Place of Presentation
  神戸、神戸ポートピアホテル(招待講演)
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-21590328
[Presentation] Negative regulation of TGF-β signaling by TMEPAI and its possible involvement for tumorigenicity2010
- Author(s)
  Itoh S
- Organizer
  BMB2010
- Place of Presentation
  神戸ポートピアホテル、神戸
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-21590328
[Presentation] Regulation of TGF-β signaling by TMEPAI family2010
- Author(s)
  Itoh S
- Organizer
  TGF-β meeting in Leiden
- Place of Presentation
  Leiden The Netherlands
- Year and Date
  2010-09-02
- Data Source
  KAKENHI-PROJECT-21590328
[Presentation] Vascular endothelial cell-specific Smad2 and Smad3 signaling is required for blood vessel integrity.2010
- Author(s)
  Itoh F., et al
- Organizer
  The 59^<th> Fujihara International Seminar
- Place of Presentation
  Tomakomai, grand hotel new Oji
- Year and Date
  2010-07-16
- Data Source
  KAKENHI-PROJECT-21590328
[Presentation] Regulation of TGF-β signaling by TMEPAI family.2010
- Author(s)
  Itoh S.
- Organizer
  TGF-β meeting in Leiden
- Place of Presentation
  Leiden, The Netherlands(招待講演)
- Year and Date
  2010-09-02
- Data Source
  KAKENHI-PROJECT-21590328
[Presentation] TGF-βシグナル抑制分子TMEPAI遺伝子の転写制御-TGF-βシグナルとWntシグナルによる協調作用2010
- Author(s)
  中野なおこ、加藤光保、伊東進
- Organizer
  聖マリアンナ医科大学医学会第59回学術集会
- Place of Presentation
  川崎、聖マリアンナ医科大学
- Year and Date
  2010-07-23
- Data Source
  KAKENHI-PROJECT-21590328
[Presentation] Monoclonal antibody for TMEPAI.2010
- Author(s)
  Vo Nguyen TT, Watanabe Y., Itoh S., Kato M.
- Organizer
  BMB2010
- Place of Presentation
  神戸、神戸ポートピアホテル
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-21590328
[Presentation] Inhibition of endothelial cell activation by bHLH protein E2-22009
- Author(s)
  Susumu Itoh
- Organizer
  TGF-beta meeting in Uppsala
- Place of Presentation
  Uppsala, Sweden
- Year and Date
  2009-08-31
- Data Source
  KAKENHI-PROJECT-21590328
[Presentation] bHLH protein E2-2 inhibits VEGFR2 expression and blocks endothelial cell activation2009
- Author(s)
  伊東史子, 他
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2009-10-02
- Data Source
  KAKENHI-PROJECT-21590328
[Presentation] Role of TMEPAI in negative feedback loop of TGF-beta signaling.2009
- Author(s)
  Susumu itoh
- Organizer
  Joint symposium in biological sciences
- Place of Presentation
  Suwon, Korea
- Year and Date
  2009-11-14
- Data Source
  KAKENHI-PROJECT-21590328
[Presentation] Impairment of vascular stability by endothelial specific ablation for Smad2 and Smad3 genes2009
- Author(s)
  伊東史子, 他
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-12-11
- Data Source
  KAKENHI-PROJECT-21590328
[Presentation] Elucidation of the inhibitory mechanism of PDZK1IP1 against TGF-β/Smad signaling.
- Author(s)
  Ikeno, S., Takeda, T., Ichikawa, D., Nakano, N., Minowa, T., Hanagata, N., Itoh, F., and Itoh, S.
- Organizer
  Ludwig TGF-β Meeting in Leiden
- Place of Presentation
  LUMC, Leiden, The Netherlands
- Year and Date
  2014-05-08 – 2014-05-10
- Data Source
  KAKENHI-PROJECT-26305006
[Presentation] Negative regulation of TGF-β signaling by TMED10.
- Author(s)
  Itoh, S
- Organizer
  Ludwig TGF-β Meeting in Leiden
- Place of Presentation
  LUMC, Leiden, The Netherlands
- Year and Date
  2014-05-08 – 2014-05-10
- Data Source
  KAKENHI-PROJECT-26305006
[Presentation] Transcriptional Repression Mechanisms of TGF-β Signaling and ATBF1 on the AFP Promoter
- Author(s)
  Nobuo Sakata, Satoshi Kaneko, Souichi Ikeno, Yutaka Miura, Hidekazu Nakabayashi, Xue-Yuan Dong, Jin-Tang Dong, Taiki Tamaki, Naoko Nakano, Susumu Itoh
- Organizer
  Joint International Symposium on TGF-β Family and Cancer “Signal Network in Tumor Microenvironment”
- Place of Presentation
  つくば国際会議場（つくば市）
- Year and Date
  2015-01-12 – 2015-01-13
- Data Source
  KAKENHI-PROJECT-25670168
[Presentation] The functional relationship between C18ORF1 and TMEPAI in TGF-β/Smad signaling.
- Author(s)
  Nakano, N., Maeyama, M., Sakata, N., Itoh, F., Akatsu, R., Nakata, M., Katsu, Y., Ikeno, S., Togawa, Y., Vo Nguyen, T. T., Watanabe, Y., Kato, M., and Itoh, S.
- Organizer
  Ludwig TGF-β Meeting in Leiden
- Place of Presentation
  LUMC, Leiden, The Netherlands
- Year and Date
  2014-05-08 – 2014-05-10
- Data Source
  KAKENHI-PROJECT-26305006
[Presentation] TGF-β/Smadシグナル伝達系と転写因子ATBF1によるα-fetoprotein遺伝子転写抑制
- Author(s)
  坂田宣夫、金子哲士、池野聡一、三浦裕、中林秀和、Xue-Yuan Dong、Jin-Tang Dong、玉置大器、中野なおこ、伊東進
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸国際会議場（神戸市）
- Data Source
  KAKENHI-PROJECT-25670168
[Presentation] Fine-tuning of TGF-β signaling
- Author(s)
  Itoh, S
- Organizer
  1st symposium of SPU Innovative project for Pharmaceutical Anaylses of Covalent Modification in Biomolecules
- Place of Presentation
  Showa Pharmaceutical Univ., Machida, Japan
- Year and Date
  2014-08-28 – 2014-08-29
- Invited
- Data Source
  KAKENHI-PROJECT-26305006
[Presentation] Negative regulation of α-fetoprotein gene transcription by TGF-β signaling with AT motif binding factor 1 (ATBF1)
- Author(s)
  Nobuo Sakata, Satoshi Kaneko, Souichi Ikeno, Yutaka Miura, Hidekazu Nakabayashi, Xue-Yuan Dong, Jin-Tang Dong, Taiki Tamaki, Naoko Nakano, Susumu Itoh
- Organizer
  TGF-β Meeting in Leiden 2014 “TGF-β signal transduction in human disease”
- Place of Presentation
  Leiden Univ. Med. Center (Leiden, NL)
- Year and Date
  2014-05-07 – 2014-05-10
- Data Source
  KAKENHI-PROJECT-25670168
[Presentation] TGF-β Signaling Cooperates with AT Motif Binding Factor 1 (ATBF1) to Repress α-Fetoprotein Gene in Human Hepatoma Cells.
- Author(s)
  Nobuo Sakata, Satoshi Kaneko, Souichi Ikeno, Yutaka Miura, Hidekazu Nakabayashi, Taiki Tamaki, Naoko Nakano, Susumu Itoh
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Data Source
  KAKENHI-PROJECT-25670168
[Presentation] 2.TGF-β signaling cooperate with ATBF1 in AFP transcription
- Author(s)
  Nobuo Sakata, Satoshi Kaneko, Souichi Ikeno, Yutaka Miura, Hidekazu Nakabayashi, Xue-Yuan Dong, Jin-Tang Dong, Taiki Tamaki, Naoko Nakano, Susumu Itoh
- Organizer
  The 3rd International Symposium by JSPS Core-to-Core Program “Cooperative International Framework in TGF-β Family Signaling”
- Place of Presentation
  大和屋本店（松山市）
- Data Source
  KAKENHI-PROJECT-25670168
[Presentation] Negative regulation of α-fetoprotein gene transcription by TGF-β/Smad signaling with AT motif binding factor 1 (ATBF1)TGF-β signaling cooperates with AT motif-binding factor-1
- Author(s)
  Sakata, N., Kaneko, S., Ikeno, S., Miura, Y., Nakabayashi, H., Dong, X.-Y., Dong, J.-T., Tamaoki, T., Nakano, N., and Itoh, S
- Organizer
  Ludwig TGF-β Meeting in Leiden
- Place of Presentation
  LUMC, Leiden, The Netherlands
- Year and Date
  2014-05-08 – 2014-05-10
- Data Source
  KAKENHI-PROJECT-26305006
[Presentation] Transcriptional repression mechanisms of TGF-β signaling and ATBF1 on the AFP promoter
- Author(s)
  Sakata, N., Kaneko, S., Ikeno, S., Miura, Y., Nakabayashi, H., Dong, X.-Y., Dong, J.-T., Tamaoki, T., Nakano, N., and Itoh, S.
- Organizer
  Joint International Symposium on TGF-β Family and Cancer: Signal Network in Tumor Microenvironment
- Place of Presentation
  Tsukuba International Congress Center, Tsukuba, Japan
- Year and Date
  2015-01-12 – 2015-01-13
- Data Source
  KAKENHI-PROJECT-26305006
[Presentation] TMEPAIファミリーによるTGF-βシグナル抑制機構
- Author(s)
  中野なおこ、伊東史子、渡邊幸秀、加藤光保、伊東進
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜、横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26305006

1. YOKOI Tsuyoshi (70135226)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
2. KAMATAKI Tetsuya (00009177)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
3. 澤田稔 (30215917)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
4. KITAMURA Ryuji (40221212)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. TAKANO Shingo (50292553)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. OHNEDA Osamu (30311872)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. EMA Masatsugu (60359578)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. ISHIKAWA Eiichi (30510169)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. KUBOTA Yoshiaki (50348687)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. SAKATA Nobuo (00170598)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
11. SAKUMA Tsutomu (30250468)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. KATO Mitsuyasu (20194855)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
13. SUZUKI Hiroyuki (70375509)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 伊東史子 (70502582)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
15. 高野昭人 (00255910)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
16. 中根孝久 (80384634)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
17. HASEGAWA Hiroshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. SUZUKI Atsushi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. DEMIZU YOSUKE

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. NATSUME Tohru

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. WATANABE Takuya

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 金保安則

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 中野なおこ

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
24. 内藤幹彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
25. 服部隆行

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 田代悦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. 渡邊幸秀

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Itoh Susumu 伊東 進

ITOH Susumu 伊東 進

伊東 進 イトウ ススム

伊藤 進 イトウ ススム

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Co-Researchers

Collapse of intestinal epithelial tissue and its maintenance through TGF-beta family signalPrincipal Investigator

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Exploration of novel drug materials from natural products of Himalayan areaPrincipal Investigator

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Tumorigenicity by TGF-βsignalingPrincipal Investigator

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Regulation of endothelial cell activation by TGF-β family signalingPrincipal Investigator

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カルシウム欠乏 疾患関連遺伝子の解析と遺伝子診断への応用・・・ビタミンD合成酵素を中心として・・・Principal Investigator

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生体内活性型ビタミンD量を調節する酵素遺伝子の構造と機能解析Principal Investigator

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P4501A1遺伝子の転写制御を司るAhレセプターの構造と機能解析・・・遺伝子診断への応用・・・・Principal Investigator

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Gene targeting法を利用した薬物代謝酵素欠損マウスの作出Principal Investigator

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Principal Investigator

Itoh Susumu 伊東進

ITOH Susumu 伊東進

伊東進イトウススム

伊藤進イトウススム

カルシウム欠乏疾患関連遺伝子の解析と遺伝子診断への応用・・・ビタミンD合成酵素を中心として・・・Principal Investigator