Tatsumi Kohei 辰巳公平

… Alternative Names

TATSUMI Kohei 辰巳公平

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Researcher Number	70555432
Other IDs
Affiliation (Current)	2025: 奈良県立医科大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2025: 奈良県立医科大学, 医学部, 准教授 2019 – 2023: 奈良県立医科大学, 医学部, 准教授 2016 – 2018: 近畿大学, 医学部, 講師 2009 – 2011: 東京女子医科大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 53030:Respiratory medicine-related / Basic Section 56020:Orthopedics-related / Digestive surgery Except Principal Investigator Transformative Research Areas, Section (II) / Medium-sized Section 52:General internal medicine and related fields / Basic Section 90120:Biomaterials-related / Drug development chemistry / Biomedical engineering/Biological material science
Keywords	Principal Investigator tissue factor / ADAMTS13 / 組織因子 / factor VIII / inflammation / lung / VWF / 骨密度 / Tissue factor / 骨代謝 … More / 骨粗鬆症 / 糖尿病 / 破骨細胞 / 骨修復 / 糖尿病性骨粗鬆症 / 線溶 / 凝固 / 組織因子 (TF) / オキサリプラチン / TF / PAI-1 / 線溶因子 / 凝固因子 / 肝類洞閉塞症候群 … More Except Principal Investigator 血管内皮前駆細胞 / 細胞シート / 間葉系幹細胞 / 細胞治療 / 抗血栓薬 / 止血薬 / 血栓症 / 止血異常症 / マウス / 第VIII因子 / iPS細胞 / 肝類洞内皮細胞 / 凝固第VIII因子 / 血友病A / 血管前駆細胞 / mRNA送達 / 脈管形成 / 血管新生 / 分化誘導 / 脂肪組織由来間葉系幹細胞 / アディポカイン / メタボリックシンドローム / 脂肪由来幹細胞 / 2型糖尿病 / 慢性炎症 / 免疫隔離 / 細胞表面修飾 / 遺伝子治療 / 再生医療 / 細胞・組織工学 Less

Development of therapeutic drugs using precision polymers for hemostatic disorders and thrombotic diseases
- Principal Investigator
  
  嶋緑倫
- Project Period (FY)
  2025 – 2029
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (II)
- Research Institution
  Nara Medical University
The role of VWF and VWF-related factors in the pathogenesis of inflammatory lung diseasesPrincipal Investigator
- Principal Investigator
  
  辰巳公平
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Nara Medical University
Development of Universal Cell Therapy for Hemophilia A 
- Principal Investigator
  
  Shima Midori
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 52:General internal medicine and related fields
- Research Institution
  Nara Medical University
Role of tissue factor in diabetic osteoporosisPrincipal Investigator
- Principal Investigator
  
  Tatsumi Kohei
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Nara Medical University
  Kindai University
Induction of vasculogenesis and angiogenesis in three-dimensional tissues by using protein expressions with mRNA delivery
- Principal Investigator
  
  Kobayashi Jun
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 90120:Biomaterials-related
- Research Institution
  Tokyo Women's Medical University
The role of blood coagulation and fibrinolysis system in the oxaliplatin-induced liver sinusoidal obstruction syndromePrincipal Investigator
- Principal Investigator
  
  TATSUMI Kohei
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Digestive surgery
- Research Institution
  Kindai University
Development of novel strategy for suppressing chronic inflammation in adipose tissues utilizing adipose-derived stem cells.
- Principal Investigator
  
  ISHIDA Masayoshi
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Drug development chemistry
- Research Institution
  Kindai University
  University of the Ryukyus
Development of liver-target therapy based on cellular modification technology
- Principal Investigator
  
  OHASHI Ohashi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Tokyo Women's Medical University

All 2022 2021 2018 2017 2012 2011 2010 2009

All Journal Article Presentation

[Journal Article] Should patients with haemophilia receive gene therapy?2022
- Author(s)
  VandenDriessche T, Tatsumi K, Shima M.
- Journal Title
  
  Lancet Haematol.
  
  Volume: 9 Issue: 10 Pages: e722-e723
- DOI
  10.1016/s2352-3026(22)00300-3
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H00531
[Journal Article] Development of alternative gene transfer techniques for ex vivo and in vivo gene therapy in a canine model2021
- Author(s)
  Noda Masashi、Tatsumi Kohei、Matsui Hideto、Matsunari Yasunori、Sato Takeshi、Fukuoka Yasushi、Hotta Akitsu、Okano Teruo、Kichikawa Kimihiko、Sugimoto Mitsuhiko、Shima Midori、Nishio Kenji
- Journal Title
  
  Regenerative Therapy
  
  Volume: 18 Pages: 347-354
- DOI
  10.1016/j.reth.2021.08.009
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H00531
[Journal Article] 血友病に対する遺伝子細胞治療2021
- Author(s)
  辰巳公平、三谷成二、小野寺悠、古川千裕、野田正志
- Journal Title
  
  バイオマテリアルー生体材料ー
  
  Volume: 39 Pages: 234-239
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H00531
[Journal Article] Roles of irisin in the linkage from muscle to bone during mechanical unloading in mice2018
- Author(s)
  Kawao N, Moritake A, Tatsumi K, Kaji H
- Journal Title
  
  Calcified Tissue International
  
  Volume: － Issue: 1 Pages: 24-34
- DOI
  10.1007/s00223-018-0387-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-15H05940, KAKENHI-PROJECT-16H07357, KAKENHI-PROJECT-15K08220, KAKENHI-PROJECT-16K08534, KAKENHI-ORGANIZER-15H05935
[Journal Article] Adult hepatocytes direct liver organogenesis through non-parenchymal cell recruitment in the kidney.2018
- Author(s)
  Utoh R, Komori J, Kuge H, Tatsumi K, Yamada M, Hirohashi S, Tsutsumi M, Amanuma T, Yoshioka A, Nakajima Y, Wake K, Okano T, Lagasse E, Ohashi K.
- Journal Title
  
  J Hepatol.
  
  Volume: 68 Issue: 4 Pages: 744-753
- DOI
  10.1016/j.jhep.2017.12.016
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H07357, KAKENHI-PROJECT-16J40041, KAKENHI-PROJECT-16K01355, KAKENHI-PROJECT-26350530
[Journal Article] Role of Macrophages and Plasminogen Activator Inhibitor-1 in Delayed Bone Repair in Diabetic Female Mice2018
- Author(s)
  Shimoide Takeshi、Kawao Naoyuki、Tamura Yukinori、Okada Kiyotaka、Horiuchi Yoshitaka、Okumoto Katsumi、Kurashimo Shinji、Ishida Masayoshi、Tatsumi Kohei、Matsuo Osamu、Kaji Hiroshi
- Journal Title
  
  Endocrinology
  
  Volume: 159 Issue: 4 Pages: 1875-1885
- DOI
  10.1210/en.2018-00085
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K18256, KAKENHI-PLANNED-15H05940, KAKENHI-PROJECT-16H07357, KAKENHI-PROJECT-15K08220, KAKENHI-PROJECT-18K06863, KAKENHI-PROJECT-16K08534, KAKENHI-PROJECT-16K10924, KAKENHI-ORGANIZER-15H05935
[Journal Article] Role of follistatin in muscle and bone alterations induced by gravity change in mice.2018
- Author(s)
  Kawao N, Morita H, Obata K, Tatsumi K, Kaji H.
- Journal Title
  
  J Cell Physiol.
  
  Volume: 233 Issue: 2 Pages: 1191-1201
- DOI
  10.1002/jcp.25986
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08534, KAKENHI-PLANNED-15H05940, KAKENHI-PROJECT-16H07357, KAKENHI-PROJECT-15K08220, KAKENHI-PROJECT-15K11916, KAKENHI-ORGANIZER-15H05935
[Journal Article] Hepatocyte Transplantation: Cell Sheet Technology for Liver Cell Transplantation.2017
- Author(s)
  Tatsumi K, Okano T
- Journal Title
  
  Curr Transplant Rep.
  
  Volume: 4 Issue: 3 Pages: 184-192
- DOI
  10.1007/s40472-017-0156-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H07357
[Journal Article] Protease-Activated Receptor 1 Enhances Poly I:C Induction of the Antiviral Response in Macrophages and Mice.2017
- Author(s)
  Antoniak S, Tatsumi K, Bode M, Vanja S, Williams JC, Mackman N
- Journal Title
  
  J Innate Immun.
  
  Volume: 9 Issue: 2 Pages: 181-192
- DOI
  10.1159/000450853
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H07357
[Journal Article] 細胞シート工学を用いた血友病新規治療2017
- Author(s)
  辰巳公平、大橋一夫
- Journal Title
  
  Frontiers in Haemophilia
  
  Volume: 4 Pages: 19-24
- Data Source
  KAKENHI-PROJECT-16H07357
[Journal Article] 肝細胞移植による血友病治療2017
- Author(s)
  辰巳公平、大橋一夫
- Journal Title
  
  Frontiers in Haemophilia
  
  Volume: 4 Pages: 17-22
- Data Source
  KAKENHI-PROJECT-16H07357
[Journal Article] Effects of hypergravity on gene levels in anti-gravity muscle and bone through the vestibular system in mice.2017
- Author(s)
  Kawao N, Morita H, Nishida K, Obata K, Tatsumi K, Kaji H.
- Journal Title
  
  J Physiol Sci.
  
  Volume: － Issue: 5 Pages: 609-616
- DOI
  10.1007/s12576-017-0566-4
- NAID
  40021645358
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08534, KAKENHI-PROJECT-16H07357, KAKENHI-PROJECT-15K08220, KAKENHI-PROJECT-15K11916, KAKENHI-PROJECT-18K06850, KAKENHI-PLANNED-15H05940, KAKENHI-ORGANIZER-15H05935
[Journal Article] Plasminogen activator inhibitor-1 deficiency enhances subchondral osteopenia after induction of osteoarthritis in mice.2017
- Author(s)
  Moritake A, Kawao N, Okada K, Tatsumi K, Ishida M, Okumoto K, Matsuo O, Akagi M, Kaji H.
- Journal Title
  
  BMC Musculoskelet Disord.
  
  Volume: 18 Issue: 1 Pages: 392-392
- DOI
  10.1186/s12891-017-1752-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08534, KAKENHI-PROJECT-17K18256, KAKENHI-PROJECT-16H07357, KAKENHI-PROJECT-15K08220
[Journal Article] The non-invasive cell surface modification of hepatocytes with PEG-lipid derivatives2012
- Author(s)
  Tatsumi K, Ohashi K, Teramura Y, 他7名
- Journal Title
  
  Biomaterials
  
  Volume: 33 Pages: 821-828
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300180
[Journal Article] The non-invasive cell surface modification of hepatocytes with PEG-lipid derivatives2011
- Author(s)
  Tatsumi K, Ohashi K, et al
- Journal Title
  
  Biomaterials
  
  Volume: 33 Issue: 3 Pages: 821-828
- DOI
  10.1016/j.biomaterials.2011.10.016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300180
[Journal Article] Human hepatocyte propagation system in the mouse livers : functional maintenance of the production of_coagulation and anti-coagulation factors2011
- Author(s)
  Tatsumi K, Ohashi K, et al.
- Journal Title
  
  Cell Transplantation
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300180
[Journal Article] Human hepatocyte propagation system in the mouse livers : Functional maintenance of the production of coagulation and anti-coagulation factors2010
- Author(s)
  Tatsumi K, Ohashi K, et al.
- Journal Title
  
  Cell Transplantation (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300180
[Journal Article] Engineering liver tissues under the kidney capsule sites provides therapeutic effects on hemophilia B2010
- Author(s)
  Ohashi K, Tatsumi K, et al.
- Journal Title
  
  Cell Transplantation (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300180
[Journal Article] Engineering liver tissues under the kidney capsule sites provides therapeutic effects on hemophilia B2010
- Author(s)
  Ohashi K, Tatsumi K, et al.
- Journal Title
  
  Cell Transplantation
  
  Volume: 19 Pages: 807-813
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300180
[Journal Article] Liver tissue engineering utilizing hepatocytes propagated in mouse livers in vivo2010
- Author(s)
  Ohashi K, Tatsumi K, et al.
- Journal Title
  
  Cell Transplantation (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300180
[Journal Article] Engineering liver tissues under the kidney capsule site provides therapeutic effects to hemophilia B mice2010
- Author(s)
  Ohashi K, Tatsumi K, Utoh R, 他3名
- Journal Title
  
  Cell Transplantation
  
  Volume: 19 Pages: 807-813
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300180
[Journal Article] Functional life-long maintenance of engineered liver tissue in mice foliowing transplantation under the kidney capsule2010
- Author(s)
  Ohashi K, Tatsumi K, et al.
- Journal Title
  
  J Tissue Eng Reg Med
  
  Volume: 4 Pages: 141-148
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300180
[Journal Article] Effects on coagulation factor production following primary hepatomitogen-induced direct hyperplasia2009
- Author(s)
  Tatsumi K, Ohashi K, et al.
- Journal Title
  
  World Journal of Gastroenterology 15
  
  Pages: 5307-5315
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300180
[Presentation] 間葉系幹細胞から肝類洞内皮細胞への分化誘導技術開発2022
- Author(s)
  三谷成二、小野寺悠、古川（細田）千裕、嶋緑倫、辰巳公平
- Organizer
  第29回肝細胞研究会
- Data Source
  KAKENHI-PROJECT-20H00531
[Presentation] 糖尿病による骨修復遅延におけるtissue factorの関与2021
- Author(s)
  辰巳公平
- Organizer
  第43回日本血栓止血学会学術集会
- Data Source
  KAKENHI-PROJECT-18K09123
[Presentation] Anticoagulants increase alveolar hemorrhage after influenza A infection in mice2017
- Author(s)
  Kohei Tatsumi
- Organizer
  第26回国際血栓止血学会（Inernational Society on Thrombosis and Haemostasis；ISTH)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H07357
[Presentation] 重症H1N1インフルエンザAウィルス感染患者の予後予測マーカーとしての血漿中マイクロパーティクル由来組織因子活性値とインターロイキン-8値の有用性2017
- Author(s)
  辰巳公平
- Organizer
  第17回TTMフォーラム
- Data Source
  KAKENHI-PROJECT-16H07357
[Presentation] Role of coagulation factors in a mouse model of influenza virus infection2017
- Author(s)
  辰巳公平
- Organizer
  第39回日本血栓止血学会
- Invited
- Data Source
  KAKENHI-PROJECT-16H07357
[Presentation] 凝固因子発現からみた血管内皮積層化培養肝細胞の機能評価2017
- Author(s)
  辰巳公平
- Organizer
  第16回日本再生医療学会
- Data Source
  KAKENHI-PROJECT-16H07357
[Presentation] The role of hepatocyte tissue factor in the hypercoagulable state observed in chronic liver injury2017
- Author(s)
  辰巳公平
- Organizer
  第94回日本生理学会
- Data Source
  KAKENHI-PROJECT-16H07357
[Presentation] Hepatocyte tissue factor contributes to the hypercoagulable state in chronic liver injury of mice2017
- Author(s)
  辰巳公平
- Organizer
  第79回日本血液学会
- Data Source
  KAKENHI-PROJECT-16H07357
[Presentation] In vivo propagation and genetic modification of hepatocytes toward gene and cell therapy2011
- Author(s)
  Tatsumi K, Ohashi K, Tateno C, 他5名
- Organizer
  Joint Congress of Cell Transplant Society and International Xenotransplantation Society
- Place of Presentation
  Miami(USA)
- Year and Date
  2011-10-25
- Data Source
  KAKENHI-PROJECT-21300180
[Presentation] Hepatocyte Surface Modification for Liver Regenerative Medicine2010
- Author(s)
  Tatsumi K, Ohashi K, et al.
- Organizer
  TERIS 201 Asia Pacific Meeting
- Place of Presentation
  Sydney, Australia
- Year and Date
  2010-09-16
- Data Source
  KAKENHI-PROJECT-21300180
[Presentation] Novel Approach for Cell and Gene Therapy of Hemophlia B Based on a Creation of Alter Ego2010
- Author(s)
  辰巳公平、大橋一夫, 他
- Organizer
  第72回日本血液学会学術集会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-21300180
[Presentation] Hepatocyte surface modification for liver regenerative medicine2010
- Author(s)
  Tatsumi K, Ohashi K, Utoh R, 他3名
- Organizer
  Tissue Engineering & Regenerative Medicine International Society 2010 Asia Pacific Meeting
- Place of Presentation
  Sydey(Australia)
- Year and Date
  2010-09-16
- Data Source
  KAKENHI-PROJECT-21300180

1. NAKAYAMA Masamichi (00338980)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. KAJI Hiroshi (90346255)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
3. Shima Midori (30162663)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
4. 坂田飛鳥 (90528457)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. OHASHI Ohashi (40364062)

# of Collaborated Projects: 1 results

# of Collaborated Products: 14 results
6. IWATA Hiroo (30160120)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. MIZUGUCHI Hiroyuki (50311387)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. ISHIDA Masayoshi (50643251)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. Kobayashi Jun (20385404)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 秋山義勝 (20349640)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 増田信奈子 (30342851)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 山岡哲二 (50243126)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 長瀬健一 (10439838)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 堀江恭二 (30333446)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 小田朗永 (80547703)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
16. 荻原建一 (50623500)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 野上恵嗣 (50326328)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. Mackman Nigel

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
19. MORITA Hironobu

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
20. OKUMOTO katsumi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 河尾直之

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results

Tatsumi Kohei 辰巳 公平

TATSUMI Kohei 辰巳 公平

Research Projects

Research Products

Co-Researchers

Development of therapeutic drugs using precision polymers for hemostatic disorders and thrombotic diseases

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The role of VWF and VWF-related factors in the pathogenesis of inflammatory lung diseasesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of Universal Cell Therapy for Hemophilia A&#160;

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Role of tissue factor in diabetic osteoporosisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Induction of vasculogenesis and angiogenesis in three-dimensional tissues by using protein expressions with mRNA delivery

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The role of blood coagulation and fibrinolysis system in the oxaliplatin-induced liver sinusoidal obstruction syndromePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of novel strategy for suppressing chronic inflammation in adipose tissues utilizing adipose-derived stem cells.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of liver-target therapy based on cellular modification technology

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Should patients with haemophilia receive gene therapy?2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Development of alternative gene transfer techniques for ex vivo and in vivo gene therapy in a canine model2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 血友病に対する遺伝子細胞治療2021

Author(s)

Journal Title

Data Source

[Journal Article] Roles of irisin in the linkage from muscle to bone during mechanical unloading in mice2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Adult hepatocytes direct liver organogenesis through non-parenchymal cell recruitment in the kidney.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Role of Macrophages and Plasminogen Activator Inhibitor-1 in Delayed Bone Repair in Diabetic Female Mice2018

Author(s)

Journal Title

Tatsumi Kohei 辰巳公平

TATSUMI Kohei 辰巳公平

Development of Universal Cell Therapy for Hemophilia A