Tokuda Emi 徳田恵美

… Alternative Names

徳田恵美トクダエミ

TOKUDA Emi 徳田恵美

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Researcher Number	70621960
Other IDs
Affiliation (Current)	2025: 福島県立医科大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2021 – 2023: 福島県立医科大学, 医学部, 講師 2016: 順天堂大学, 医学部, 非常勤助教 2015: 神戸大学, 大学院医学研究科, 特任助教 2013 – 2015: 順天堂大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 55010:General surgery and pediatric surgery-related / General surgery Except Principal Investigator Functional biochemistry / Radiation science
Keywords	Principal Investigator ER発現の可塑性 / ER陽性進行再発乳癌 / 内分泌耐性 / ER発現メカニズム / PI3K阻害薬 / 内分泌療法耐性乳癌 / 薬物治療抵抗性 / ＥＲ：ＨＥＲ２ / 薬物療法抵抗性 / ＥＲ陽性ＨＥＲ陽性 … More / 乳癌 / ERシグナル亢進 / ハーセプチン耐性 / クロストーク / 薬剤耐性 / ER陽性HER2陽性乳癌 … More Except Principal Investigator F-Barドメイン / 脂質結合蛋白質 / PIP3 ホスファターゼ / 膜変形 / インスリン　シグナル / PI4P / Sac1 / SKIP / インスリン / ホスホイノシタイド　５－ホスファターゼ / 脂質結合タンパク質 / 膜形成 / がん細胞転移 / インスリンシグナル / 膜の形 / ホスホイノシタイド / 放射線治療 / 細胞浸潤能 / 細胞遊走能 / 生物学的効果比 / 放射線感受性 / 重粒子線治療 / 乳癌 / 炭素イオン線 Less

細胞内シグナル伝達阻害薬が内分泌療法耐性乳癌の治療感受性を回復させる機序の解明Principal Investigator
- Principal Investigator
  
  徳田恵美
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Fukushima Medical University
Elucidation of the interaction between crosstalk between ER and HER2 and drug resistance mechanism in breast cancerPrincipal Investigator
- Principal Investigator
  
  TOKUDA Emi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General surgery
- Research Institution
  Juntendo University
Basic Research for Carbon-Ion Radiotherapy for Breast Cancer
- Principal Investigator
  
  Karasawa Kumiko
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Tokyo Women's Medical University
  National Institute of Radiological Sciences
Regulation of cell dynamism by phosphoinositides
- Principal Investigator
  
  Takenawa Tadaomi
- Project Period (FY)
  2011 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Functional biochemistry
- Research Institution
  Kobe University

All 2023 2022 2021 2017 2016 2015 2014 2013 2012 Other

All Journal Article Presentation

[Journal Article] The Impact of Being Underweight on the Prognosis of Older Patients With Early Breast Cancer2023
- Author(s)
  ISHIZUKA YUMIKO、HORIMOTO YOSHIYA、MORITA MIDORI、KAWAMURA YUKINO、SEKINE KATSUTOSHI、OBAYASHI SAYAKA、KOJIMA YUKI、TOKUDA EMI、HIGUCHI TORU、SHIMOMURA AKIHIKO
- Journal Title
  
  Cancer Diagnosis & Prognosis
  
  Volume: 3 Issue: 6 Pages: 678-686
- DOI
  10.21873/cdp.10272
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08599
[Journal Article] Is adjuvant chemotherapy necessary in older patients with breast cancer?2022
- Author(s)
  Morita Midori、Shimomura Akihiko、Tokuda Emi、Horimoto Yoshiya、Kawamura Yukino、Ishizuka Yumiko、Sekine Katsutoshi、Obayashi Sayaka、Kojima Yuki、Uemura Yukari、Higuchi Toru
- Journal Title
  
  Breast Cancer
  
  Volume: 29 Issue: 3 Pages: 498-506
- DOI
  10.1007/s12282-021-01329-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08599
[Journal Article] Everolimus+Exemestane療法後に腫瘍崩壊症候群をきたした進行乳癌の一例2021
- Author(s)
  竹村真生子, 岡崎護, 羽成直行, 徳田恵美, 田辺真彦, 林嗣博, 水谷知央, 林孝朗, 中村優飛, 根本悠里, 佐久間芽衣, 叶多諒, 萩尾浩太郎, 絹田俊爾, 山口佳子, 輿石直樹
- Journal Title
  
  福島医学雑誌
  
  Volume: 21 Pages: 35-40
- NAID
  40022601256
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08599
[Journal Article] ホルモン療法の感受性マーカー2017
- Author(s)
  徳田恵美　林慎一
- Journal Title
  
  がん分子標的治療
  
  Volume: 15 Pages: 66-71
- Open Access
- Data Source
  KAKENHI-PROJECT-26861055
[Journal Article] Phosphatidylinositol 4-phosphate in the Golgi apparatus regulates cell-cell adhesion, cell migration and invasion in human breast cancer2014
- Author(s)
  Tokuda E., Itoh T., Hasegawa J., Ijuin T., Takeuchi Y., Irino, Y., Fukumoto M., and Takenawa T.
- Journal Title
  
  Cancer Res. 74, 3054-3066 (2014)
  
  Volume: 74 Pages: 3054-3066
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-23227005
[Journal Article] Phosphatidylinositol 4-phosphate in the Golgi apparatus regulates cell-cell adhesion, and invasive cell migration in human breast cancer2014
- Author(s)
  Tokuda E., Itoh T., Hasegawa J., Ijuin T., Takeuchi Y., Irino, Y., Fukumoto M., and Takenawa T.
- Journal Title
  
  Cancer Res.
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23227005
[Journal Article] Ki67 expression and the effect of neo-adjuvant chemotherapy on luminal HER2-negative breast cancer.2014
- Author(s)
  Horimoto Y1, Arakawa A, Tanabe M, Sonoue H, Igari F, Senuma K, Tokuda E, Shimizu H, Kosaka T, Saito M.
- Journal Title
  
  BMC cancer
  
  Volume: 550 Issue: 1
- DOI
  10.1186/1471-2407-14-550
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26861055
[Journal Article] Quantification and visualization of phosphoinositides by quantum dot-labeled specific binding-domain probes2012
- Author(s)
  Irino Y, Tokuda E, Hasegawa J, Itoh T, Takenawa T
- Journal Title
  
  J.Lipid.Res.
  
  Volume: (Epub ahead of print)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23227005
[Presentation] Neutrophil-lymphocyte ratio and absolute lymphocyte count, inflammatory markers in elderly breast cancer, may predict lymph node metastasis in operable breast cancer.2023
- Author(s)
  Tokuda E, Morita M, Shimomura A, Horimoto Y, Kawamura Y, Ishizuka Y, Sekine K, Obayashi S, Kojima Y, Higuchi T,
- Organizer
  San Antonio Breast Cancer Symposium, San Antonio, TX, PO5-15-03, Dec 8 (10-14), 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08599
[Presentation] Biologyから考えるLuminal-HER2乳癌の治療戦略2022
- Author(s)
  徳田恵美
- Organizer
  第30回　日本乳癌学会
- Data Source
  KAKENHI-PROJECT-21K08599
[Presentation] ER発現が低下した内分泌療法耐性乳癌細胞のER発現をPI3K阻害薬が再発現させる機序にエピゲノム変化が関与する2021
- Author(s)
  徳田恵美、佐々木駿太、坪井洸樹、豊澤大地、鈴木友菜、塚原美理、佐治重衡、林　慎一
- Organizer
  第29回日本乳癌学会
- Data Source
  KAKENHI-PROJECT-21K08599
[Presentation] ER＋HER2＋に対する抗HER2療法の最新の知見（実臨床ではあえてこれを選択する）2017
- Author(s)
  徳田恵美
- Organizer
  Refinement of the treatment strategy for breast cancer
- Place of Presentation
  東京　飯田橋
- Year and Date
  2017-03-09
- Data Source
  KAKENHI-PROJECT-26861055
[Presentation] 汎クラスI PI3K阻害剤とサブユニット特異的阻害剤の各種内分泌療法耐2016
- Author(s)
  徳田恵美
- Organizer
  日本乳癌学会　学術総会
- Place of Presentation
  東京　有明ビックサイト
- Year and Date
  2016-06-16
- Data Source
  KAKENHI-PROJECT-26861055
[Presentation] 術前化学療法施行症例のＫｉ６７の発現変化と術後再発・予後との相関について2015
- Author(s)
  徳田恵美、島田聡子、猪狩史江、氷室貴規　ほか
- Organizer
  第23回日本乳癌学会　学術集会
- Place of Presentation
  東京　東京国際フォーラム
- Year and Date
  2015-07-02
- Data Source
  KAKENHI-PROJECT-26861055
[Presentation] 乳癌の化学療法効果におけるエストロゲンレセプター蛋白の発現と活性による評価の検討2015
- Author(s)
  徳田恵美，清水秀穂，堀本義哉，田辺真彦，三浦佳代，齊籐光江，林　慎一，山口ゆり
- Organizer
  第16回ホルモンと癌研究会
- Place of Presentation
  岐阜　朝日大学村上記念病院
- Year and Date
  2015-07-10
- Data Source
  KAKENHI-PROJECT-26861055
[Presentation] 乳がん細胞株においてゴルジ体のイノ　シトールリン脂質が細胞間接着と細胞運動・浸潤能を制御する2013
- Author(s)
  徳田恵美、竹縄忠臣
- Organizer
  第65回日本細胞生物学会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23227005
[Presentation] 乳癌の化学療法効果予測におけるエストロゲンレセプター発現の意義の検討
- Author(s)
  徳田　恵美、高橋　由佳、堀本　義哉、清水　秀穂、田辺　真彦、中井　克也、齊藤　光江、清野　祐子、山口　ゆり、林　慎一
- Organizer
  第２２回日本乳癌学会　学術総会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2014-07-10 – 2014-07-12
- Data Source
  KAKENHI-PROJECT-26861055
[Presentation] Triple positive乳癌におけるERとHER2の発現分布についての検討
- Author(s)
  魚森　俊喬、堀本　義哉、齊藤　光江、中井　克也、清水　秀穂、田辺　真彦、徳田　恵美、毛利かの子、荒川　敦
- Organizer
  第２２回日本乳癌学会　学術総会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2014-07-10 – 2014-07-12
- Data Source
  KAKENHI-PROJECT-26861055

1. HORIMOTO Yoshiya (40424246)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
2. Karasawa Kumiko (60214574)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. IMAI Takashi (50183009)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. FUJITA Mayumi (80580331)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. ARAKAWA Atsushi (70245695)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. Takenawa Tadaomi (40101315)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
7. ITOH Toshiki (30313092)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
8. IJUIN Takeshi (00361626)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
9. TSUJITA Kazuya (10457054)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. HASEGAWA Junya (00533788)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
11. IRINO Yasuhiro (10415565)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results

Tokuda Emi 徳田 恵美

徳田 恵美 トクダ エミ

TOKUDA Emi 徳田 恵美

Research Projects

Research Products

Co-Researchers

細胞内シグナル伝達阻害薬が内分泌療法耐性乳癌の治療感受性を回復させる機序の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the interaction between crosstalk between ER and HER2 and drug resistance mechanism in breast cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Basic Research for Carbon-Ion Radiotherapy for Breast Cancer

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Regulation of cell dynamism by phosphoinositides

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] The Impact of Being Underweight on the Prognosis of Older Patients With Early Breast Cancer2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Is adjuvant chemotherapy necessary in older patients with breast cancer?2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Everolimus+Exemestane療法後に腫瘍崩壊症候群をきたした進行乳癌の一例2021

Author(s)

Journal Title

NAID

Data Source

[Journal Article] ホルモン療法の感受性マーカー2017

Author(s)

Journal Title

Data Source

[Journal Article] Phosphatidylinositol 4-phosphate in the Golgi apparatus regulates cell-cell adhesion, cell migration and invasion in human breast cancer2014

Author(s)

Journal Title

Data Source

[Journal Article] Phosphatidylinositol 4-phosphate in the Golgi apparatus regulates cell-cell adhesion, and invasive cell migration in human breast cancer2014

Author(s)

Journal Title

Data Source

[Journal Article] Ki67 expression and the effect of neo-adjuvant chemotherapy on luminal HER2-negative breast cancer.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Quantification and visualization of phosphoinositides by quantum dot-labeled specific binding-domain probes2012

Author(s)

Journal Title

Data Source

[Presentation] Neutrophil-lymphocyte ratio and absolute lymphocyte count, inflammatory markers in elderly breast cancer, may predict lymph node metastasis in operable breast cancer.2023

Author(s)

Organizer

Data Source

[Presentation] Biologyから考えるLuminal-HER2乳癌の治療戦略2022

Author(s)

Organizer

Data Source

[Presentation] ER発現が低下した内分泌療法耐性乳癌細胞のER発現をPI3K阻害薬が再発現させる機序にエ ピゲノム変化が関与する2021

Author(s)

Organizer

Data Source

[Presentation] ER＋HER2＋に対する抗HER2療法の最新の知見（実臨床ではあえてこれを選択する）2017

Author(s)

Tokuda Emi 徳田恵美

徳田恵美トクダエミ

TOKUDA Emi 徳田恵美

[Presentation] ER発現が低下した内分泌療法耐性乳癌細胞のER発現をPI3K阻害薬が再発現させる機序にエピゲノム変化が関与する2021

[Presentation] 乳癌の化学療法効果におけるエストロゲンレセプター蛋白の発現と活性による評価の検討2015

[Presentation] 乳がん細胞株においてゴルジ体のイノ　シトールリン脂質が細胞間接着と細胞運動・浸潤能を制御する2013