CHIBA Hiroshige 千葉博茂

… Alternative Names

千葉博茂チバヒロシゲ

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Researcher Number	80105478
Other IDs
Affiliation (Current)	2025: 東京医科大学, 医学部, 名誉教授
Affiliation (based on the past Project Information) *help	2011: 東京医科大学, 医学部, 教授 2003 – 2007: 東京医科大学, 医学部, 教授 1997 – 2001: 東京医科大学, 医学部, 教授 1994 – 1995: 東京医科大学, 医学部, 教授 1993: 東京医科大学, 医学部, 助教授 1989 – 1991: 日本歯科大学, 歯学部, 助教授
Review Section/Research Field	Principal Investigator Surgical dentistry / 外科・放射線系歯学 Except Principal Investigator Surgical dentistry / Pathobiological dentistry/Dental radiology / 病態科学系歯学(含放射線系歯学) / Surgical dentistry
Keywords	Principal Investigator 骨浸潤 / ラベリング法 / 時刻描記法 / マイクロラジオグラフィ / 口腔癌 / 研磨片 / 顎骨浸潤 / 移植癌 / VX2癌 / 歯槽骨変化 … More / マイクロサ-ジェリ- / 骨変化 / 血管柄付骨移植 / 微小血管吻合 … More Except Principal Investigator TRAIL / apoptosis / squamous cell carcinoma / アポトーシス / カルボプラチン / 口腔扁平上皮癌 / Microarray / Gene / Tumor / Odontologv / マイクロアレイ / 遺伝子 / 癌 / 歯学 / Bcl-2 family proteins / new treatment modality / chemotherapeutic agents / 併用療法 / Bax-α / 難治性悪性腫瘍 / Bcl2ファミリータンパク質 / 化学療法剤抵抗性 / Bcl-2ファミリータンパク質 / 新規治療法 / 化学療法剤 / Drug-Resistance / Caspase-3 / Bcl-xL / Caboplatin / 薬剤耐性 / カスペース3 / Bcl-x_L / 扁平上皮癌 / cell culture / periodontal ligament / implant / 細胞培養 / 歯根膜 / 人工歯根 / 治療戦略 / 癌幹細胞 Less

Characterization of cancer stem cells for oral squamous cell carcinoma cells and its application for treatment of oral carcinoma
- Principal Investigator
  
  MIZUGUCHI Junichiro
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Tokyo Medical University
Comprehensive genome-wide assessment of gene a qn ssion involved in tumor development and metastasis with the goal of clinical application.
- Principal Investigator
  
  MIZUGUCHI Junitiro
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Tokyo Medical University
Therapeutic Strategy for Squamous Cell Carcinoma Resistant to Chemotherapeutic Agents
- Principal Investigator
  
  MIZUGUCHI Junichiro
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Tokyo Medical University
CISPLATIN-INDUCED APOPTOSIS AGAINST SQUAMOUS CELL CARCINOMA CELLS
- Principal Investigator
  
  MAZUGUCHI Junichiro
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  病態科学系歯学(含放射線系歯学)
- Research Institution
  Tokyo Medical University
Development and Clinical Application of artifical Periodontal Ligament.
- Principal Investigator
  
  GOTO Otohiko
- Project Period (FY)
  1997 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Tokyo Medical University
口腔癌の顎骨浸潤に関する実験的研究-大研磨片のマイクロラジオグラフィ,ラベリング法,血管造影法と染色像による骨破壊像の観察-Principal Investigator
- Principal Investigator
  
  千葉博茂
- Project Period (FY)
  1993 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  Surgical dentistry
- Research Institution
  Tokyo Medical University
微小血管吻合を利用した血管柄付腸骨移植に続く歯槽骨変化の研究Principal Investigator
- Principal Investigator
  
  千葉博茂
- Project Period (FY)
  1989 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  外科・放射線系歯学
- Research Institution
  The Nippon Dental University

All 2011 2010 2009 2008 2007 2006 2005

All Journal Article Presentation

[Journal Article] IL-27 suppresses RANKL expression in CD4+ T cells in part through STAT32011
- Author(s)
  Kamiya S, Okumura M, Chiba Y, Fukawa T, Nakamura C, Nimura N, Mizuguchi J, Wada S, Yoshimoto T
- Journal Title
  
  Immunol Lett
  
  Volume: 138 Pages: 47-53
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592564
[Journal Article] Radiation-induced malignant fibrous histiocytoma of the maxilla2011
- Author(s)
  Satomi T, Watanabe M, Kaneko T, Matsubayashi J, Nagano T, Chiba H
- Journal Title
  
  Odontology
  
  Volume: 99 Issue: 2 Pages: 203-208
- DOI
  10.1007/s10266-011-0001-x
- NAID
  10029548832
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592564, KAKENHI-PROJECT-23590416
[Journal Article] Regulation of antitumor immune responses by the IL-12 family cytokines, IL-12, IL-23, and IL-27.2010
- Author(s)
  Xu M, Mizoguchi I, Morishima N, Chiba Y, Mizuguchi J, Yoshimoto T.
- Journal Title
  
  Clin Dev Immunol
  
  Volume: 2010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592564
[Journal Article] Clinical significance of expression of thymidylate synthase and dihydropyrimidine dehydrogenase in oral squamous cell carcinoma2010
- Author(s)
  Tsuzuki M, Satomi T, Chiba H
- Journal Title
  
  Oral Med Pathol
  
  Volume: 14 Pages: 135-141
- NAID
  130004509537
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592564
[Journal Article] Interleukins and cancer immunotherapy2009
- Author(s)
  Yoshimoto T, Morishima N, Okuma M, Chiba Y, Xu M, Mizuguchi J
- Journal Title
  
  Immunotherapy1
  
  Volume: 1 Pages: 825-844
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592564
[Journal Article] Antitumor effect of Docetaxel-containing liposomes in a murine tumor model2009
- Author(s)
  Satomi T, Chiba H, Ushida T
- Journal Title
  
  Oral Oncology
  
  Volume: 3 Pages: 190-191
- Data Source
  KAKENHI-PROJECT-21592564
[Journal Article] 舌口底癌切除後再建患者の術後機能に関する主観評価-アンケートによる多施設研究-2007
- Author(s)
  松井義郎, 他30名(16番目千葉博茂)
- Journal Title
  
  口腔腫瘍(J Jpn Soc Oral Tumor) 19(1)
  
  Pages: 7-18
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390545
[Journal Article] Subjective assessment of post-operative function in patients with tumors in oral cavity. -Multicenter studies-2007
- Author(s)
  Matsui, Y, Chiba, H, et. al.
- Journal Title
  
  J Jpn Soc Oral Tumor 19-1
  
  Pages: 7-18
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390545
[Journal Article] Expression of thymidine phosphorylase and its effect on efficacy of chemotherapeutic agents in oral squamous cell carcinoma2006
- Author(s)
  Yokoh, K, Watanabe, M, Satomi, T, Matsuda, K, Tsuzuki, M, Matsuo, A, Kaneko, T, Chiba, H
- Journal Title
  
  Head and neck cancer 32-4
  
  Pages: 434-8
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390545
[Journal Article] 口腔扁平上皮癌におけるThymidine Phosphorylaseの発現と抗癌剤有効性への影響2006
- Author(s)
  横尾公子, 渡辺正人, 里見貴史, 松田憲一, 績雅子, 松尾朗, 金子忠良, 千葉博茂
- Journal Title
  
  頭頸部癌 32(4)
  
  Pages: 434-438
- NAID
  10018452674
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390545
[Presentation] Comnrahansi assessment of gene expression in primary oral squamous cell carcinoma tissues and their metastatic counterparts2008
- Author(s)
  Matsuda, K., Chiba, H, Mizueuchi, J, et. al.
- Organizer
  26th Annual Meeting of Japan Society for Oral Tumors
- Place of Presentation
  Oita Beppu
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390545
[Presentation] 口腔扁平上皮癌患者由来の原発巣及び転移巣における遺伝子発現解析2008
- Author(s)
  松田憲一, 千葉博茂, 水口純一郎, 他
- Organizer
  第26回日本口腔腫瘍学会総会
- Place of Presentation
  別府(大分県)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390545
[Presentation] Antitumor Effect of Encapsulated in Thermosensitive Liposomes Combined with Regional Hyperthermia2005
- Author(s)
  Kawai T, Satomi T, Tsuzuki M, Watanabe M, Chiba H
- Organizer
  Proceedings of the 5th congress of the international college for maxillo-facial-surgery
- Place of Presentation
  前橋(群馬県)
- Year and Date
  2005-06-09
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390545
[Presentation] Antitumor Effect of Encapsulated in Thermosensitive Liposomes Combined with Regional Hyperthermia2005
- Author(s)
  Kawai, T, Satomi, T, Tsuzuki, M, Watanabe, M, Chiba, H
- Organizer
  Proceedings of the 5th congress of the international college for maxilo-facial-surgery
- Place of Presentation
  Maebashi/Japan
- Year and Date
  2005-06-09
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390545
[Presentation] Clinical significance of the dihydropyrimidine dehydrogenase and thmidylate synthase activity in oral cancer2005
- Author(s)
  Tsuzuki, M, Satomi, T, Watanabe, M, Matsuda, K, Kuraeuchi, J, Chiba, H
- Organizer
  Proceedings of the 5th congress of the international college for maxilo-facial-surgery
- Place of Presentation
  Maebashi/Japan
- Year and Date
  2005-06-09
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390545
[Presentation] Clinical significance of the dihydropyrimidine dehydrogenase and thmidylate synthase activity in oral cancer2005
- Author(s)
  Tsuzuki M, Satomi T, Watanabe M, Matsuda K, Kuraguchi J, Chiba H
- Organizer
  Proceedings of the 5th congress of the international college for maxillo-facial-surgery
- Place of Presentation
  前橋(群馬県)
- Year and Date
  2005-06-09
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390545

1. MIZUGUCHI Junichiro (20150188)

# of Collaborated Projects: 4 results

# of Collaborated Products: 4 results
2. TAKADA Eiko (50110903)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. HATA Kikumi (30287156)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. TOYOTA Hiroko (80468660)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. MATSUO Akira (70229417)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. SATOMI Takashi (70276921)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
7. WATANABE Masato (40349460)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. GOTO Otohiko (80205591)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. YOSHIMOTO Takayuki (80202406)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. YANASE Noriko (10210303)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 勝山直彦 (10169485)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 寺辺勝之 (50120697)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 内田稔 (60095073)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 松崎俊哉 (10241051)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 下川千可志 (40226270)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 内田安信 (20074487)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

CHIBA Hiroshige 千葉 博茂

千葉 博茂 チバ ヒロシゲ

Research Projects

Research Products

Co-Researchers

Characterization of cancer stem cells for oral squamous cell carcinoma cells and its application for treatment of oral carcinoma

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Comprehensive genome-wide assessment of gene a qn ssion involved in tumor development and metastasis with the goal of clinical application.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Therapeutic Strategy for Squamous Cell Carcinoma Resistant to Chemotherapeutic Agents

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

CISPLATIN-INDUCED APOPTOSIS AGAINST SQUAMOUS CELL CARCINOMA CELLS

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development and Clinical Application of artifical Periodontal Ligament.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

口腔癌の顎骨浸潤に関する実験的研究-大研磨片のマイクロラジオグラフィ,ラベリング法,血管造影法と染色像による骨破壊像の観察-Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

微小血管吻合を利用した血管柄付腸骨移植に続く歯槽骨変化の研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] IL-27 suppresses RANKL expression in CD4+ T cells in part through STAT32011

Author(s)

Journal Title

Data Source

[Journal Article] Radiation-induced malignant fibrous histiocytoma of the maxilla2011

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Regulation of antitumor immune responses by the IL-12 family cytokines, IL-12, IL-23, and IL-27.2010

Author(s)

Journal Title

Data Source

[Journal Article] Clinical significance of expression of thymidylate synthase and dihydropyrimidine dehydrogenase in oral squamous cell carcinoma2010

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Interleukins and cancer immunotherapy2009

Author(s)

Journal Title

Data Source

[Journal Article] Antitumor effect of Docetaxel-containing liposomes in a murine tumor model2009

Author(s)

Journal Title

Data Source

[Journal Article] 舌口底癌切除後再建患者の術後機能に関する主観評価-アンケートによる多施設研究-2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] Subjective assessment of post-operative function in patients with tumors in oral cavity. -Multicenter studies-2007

CHIBA Hiroshige 千葉博茂

千葉博茂チバヒロシゲ