SEINO Susumu 清野進

Researcher Number	80236067
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2016 – 2021: 神戸大学, 医学研究科, 特命教授 2013 – 2015: 神戸大学, 医学(系)研究科(研究院), 特命教授 2012: 神戸大学, 医学(系)研究科(研究院), 教授 2011: 神戸大学, 大学院・医学研究科, 教授 2009 – 2011: Kobe University, 医学研究科, 教授 … More 2007: Kobe University, Graduate School of Medicine, Professor 2005 – 2007: 神戸大学, 医学系研究科, 教授 2003 – 2004: 神戸大学, 大学院・医学系研究科, 教授 2003: 千葉大, 医学(系)研究科(研究院), 教授 2001 – 2002: 千葉大学, 大学院・医学研究院, 教授 1998 – 2000: Chiba University, Graduate School of Medicine, Professor, 大学院・医学研究科, 教授 1998: 千葉大学, 大学院医学研究科, 教授 1992 – 1997: 千葉大学, 医学部, 教授 1994: 京都大学, 医学部, 教授 Less
Review Section/Research Field	Principal Investigator 内分泌・代謝学 / Metabolomics / Basic Section 54040:Metabolism and endocrinology-related / Metabolomics / Biological Sciences Except Principal Investigator General pharmacology / Digestive surgery / 内分泌・代謝学
Keywords	Principal Investigator インスリン / 糖尿病 / カルシウム / Insulin / G蛋白質 / Diabetes / 遺伝子 / インスリン分泌 / 開口放出 / スルホニール尿素剤 … More / イオンチャネル / ソマトスタチンアナログ / 腫瘍 / ソマトスタチン受容体 / SNPs / diabetes mellitus / スルホニール尿素受容体 / Exocytosis / ATP / Genes / insulin / インスリン非依存性糖尿病 / カリウム / Calcium / 膵β細胞 / インクレチン / 分泌 / エクソサイトーシス / 細胞増殖 / グルコース / 毒物学 / ヒ素 / Detoxification / Gene Expression / Metabolomics / Serotonin / Arsenic / Endocrin　Disruptors / Insulin Secretion / toxicology / glucuronidation / serotonin / insulin secretion / diabetes / arcenic / Gene / Insulin secretion / Bioimaging / Development&Differentiation / Cell signaling / 再生医学 / プロテオーム / バイイメージング / 発生分化 / バイオイメージング / バイオイメージング(5) / 発生・分化 / シグナル伝達 / association analysis / gene structure / gene function / genetic analysis / multifactorial disease / 多遺伝子疾患 / 原因遺伝子解析 / 相関解析 / 遺伝子構造 / 遺伝子機能 / 遺伝子解析 / 多因子疾患 / glibenclamide / inward rectfier / sulfonvlurea receptors / ATP-sensitive K^+ channels / 内向き整流性K^±チャネル / ATP感受性K^±チャネル / グリベンクラミド / 内向き整流性K^+チャネル / ATP感受性K^+チャネル / Familial hypoglycemia / Sulfonylurea receptor / ATP-sensitive K+ channels. / ATP感受性K^+-チャネル / 家族性低血糖症 / ATP感受性K+チャネル / ATP receptor / ATP受容体 / G-protein coupled receptor / Sulfonylureas / Ion channels / G蛋白質共役受容体 / カルシウムシグナル / 遺伝子変異 / K^+チャネル / G蛋白共役受容体 / sulfonylurea / potassium / calcium / Diabetes mellitus / ion channels / gene / イオンチャネルグルタミン酸受容体 / カルシウムチャネル遺伝子 / Receptor-imaging / Somatostatin Analogs / Tumors / G-protein / Somatostatin Receptors / 画像診断 / Diabetes Mellitus / Glucose / Islet of Langerhans / ブドウ糖 / 膵ランゲルハンス島 / メタボロミクス / 病態マーカー / 代謝シグナル / メタボローム解析 / 分化・再生 / 糖・脂質代謝 / 全反射型蛍光顕微鏡 / Rim2 / スルホニル尿素 / メタボローム / グルコース代謝 / トランスクリプトーム / Epac2 / cAMP / 糖質代謝異常 / エネルギー / ホルモン / Bax / Bcl2 / グルタミン酸 / アポトーシス / 小胞蛋白質 / カルシウムセンサー / シナプトタグミン / 小胞関連蛋白質 / 分泌小胞 / 低分子量G蛋白質 … More Except Principal Investigator ischemic preconditioning / Kir6.2 / ソマトスタチン受容体 / 細胞増殖抑制 / ソマトスタチン / クローニング / metabolic blockade / K^+ channel openers / Kir6.2-deficient mice / ATP-sensitive K^+ channel / ischemic preconditioning(8) / 虚血再灌流 / 代謝阻害 / K^+チャネル開口薬 / K_<ATP>チャネル欠損マウス / ATP感受性K^+チャネル / Cell proliferation / Somatostatin receptor / Somatostatin / Biliary tract tumor / Biliary tract carcinoma / 胆道癌 / 肝臓癌 / 細胞増殖 / 胆道癌 / 胆道腫瘍 / Diabetes mellitus / High fat diet / Insulin resistance / Insulin secretion / GIP modulation / GIP receptor deficient mice / ジーンターゲティング / GIP受容体 / ノックアウトマウス / GIPシグナル伝達 / 糖尿病 / 高脂肪食負荷 / インスリン抵抗性 / インスリン分泌 / GIP受容体欠損マウス / Patch-clamp method / PACAP receptor / Somatostatin Receptor / CHO cell / Xenopus Oocyte / L-type Ca channel / T-type Ca channel / PCR法 / Oocyte / ミエローマ細胞 / 遺伝子クローニング / Caチャンネル / L型カルシウムチャネル / T型カルシウムチャネル / パッチクランプ法 / PACAP受容体 / CHO細胞 / アフリカツメガエル / L型Caチャネル / T型Caチャネル / アンチポ-タ / シンポータ / 構造と機能 / チャネル / トランスポータ / イオン / c-kit受容体 / インスリン受容体 / Sky / Gas6 / GLUT4のトランスロケーション / ガストリン受容体 / HB-EGF / ErbB3 / インスリンシグナル伝達系 / スルホニール尿素受容体 / HEP受容体 / ErbBリガンド / c-Met受容体 / HGF / 細胞増殖制御 / Ras蛋白質 / がん細胞の浸潤性 / 肝細胞増殖因子 / 脱ユビキチン化酵素 / SH3ドメイン / Hrs結合蛋白質 / MAPキナーゼ / がん細胞の増殖制御 / c-Met / 肝細胞増殖因子(HGF) / 細胞内カルシウム濃度 / α_1サブユニット / 多型性 / 遺伝子構造 / チャネル活性 / 膵β細胞 / 電位依存性カルシウムチャネル Less

糖尿病におけるβ細胞Gタンパク質シグナル変換の機序、病態生理ならびに治療応用Principal Investigator
- Principal Investigator
  
  清野進
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Kobe University
糖尿病のインクレチン応答性インスリン分泌不全の分子機構解明とその治療戦略の確立Principal Investigator
- Principal Investigator
  
  清野進
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Kobe University
ヒ素による糖代謝異常における膵α細胞の役割に関する研究Principal Investigator
- Principal Investigator
  
  清野進
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Research Field
  
  Metabolomics
- Research Institution
  Kobe University
Elucidation of pancreatic beta-cell function by metabolomics and its clinical applicationPrincipal Investigator
- Principal Investigator
  
  SEINO Susumu
- Project Period (FY)
  2012 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Metabolomics
- Research Institution
  Kobe University
Mechanisms of functional expression of pancreatic islets as an integrated system and its failurePrincipal Investigator
- Principal Investigator
  
  SEINO Susumu
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Metabolomics
- Research Institution
  Kobe University
インスリン分泌システムの形成機構とその破綻Principal Investigator
- Principal Investigator
  
  清野進
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Metabolomics
- Research Institution
  Chiba University
Formation of the integrated insulin secretion system and its failurePrincipal Investigator
- Principal Investigator
  
  SEINO Susumu
- Project Period (FY)
  2003 – 2007
- Research Category
  
  Grant-in-Aid for Specially Promoted Research
- Review Section
  
  Biological Sciences
- Research Institution
  Kobe University
肝細胞増殖因子受容体(c-Met)を介するシグナル伝達の分子機構
- Principal Investigator
  
  喜多村直実 (喜多村直美)
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Tokyo Institute of Technology
Role of cardiac ATP-sensitive K^+ channels clarified by Kir6.2-deficient mice
- Principal Investigator
  
  NAKAYA Haruaki
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Chiba University
Expression of Somatostatin-Receptor and Inhibitory Effect of Somatostatin on Cell Proliferation in Hepatobiliary Malignancies
- Principal Investigator
  
  MIYAZAKI Masaru
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Chiba University
Comprehensive Analysis of Genetic Factors in Diabetes MellitusPrincipal Investigator
- Principal Investigator
  
  SEINO Susumu
- Project Period (FY)
  1998 – 2002
- Research Category
  
  Grant-in-Aid for Creative Scientific Research
- Research Institution
  Chiba University
A Screening System for Development of Novel Insulin SecretagoguesPrincipal Investigator
- Principal Investigator
  
  SEINO Susumu
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  内分泌・代謝学
- Research Institution
  Chiba University Graduate School of Medicine
Generation and analysis of GIP Receptor deficient mice
- Principal Investigator
  
  YANO hideki
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  内分泌・代謝学
- Research Institution
  Chiba University
内分泌細胞の開口放出部位は分泌刺激の違いにより異なるか?Principal Investigator
- Principal Investigator
  
  清野進
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  内分泌・代謝学
- Research Institution
  Chiba University
Construction of Molecular Map of Pancreatic beta-cell.Principal Investigator
- Principal Investigator
  
  SEINO Susumu
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Field
  
  内分泌・代謝学
- Research Institution
  Chiba University School of Medicine
低分子量G蛋白質とその標的蛋白質のインスリン分泌における意義Principal Investigator
- Principal Investigator
  
  清野進
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Chiba University
イオン駆動型トランスポーターとチャネルの構造・機能協関
- Principal Investigator
  
  土屋友房
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Okayama University
グルタミン酸受容体を発現した細胞株における細胞内情報伝達の分子機構Principal Investigator
- Principal Investigator
  
  清野進
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Chiba University
Development of super-sensitive assay for hormone secretion from single cellsPrincipal Investigator
- Principal Investigator
  
  SEINO Susumu
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  内分泌・代謝学
- Research Institution
  Chiba University School of Medicine
低分子量G蛋白質とその標的蛋白質のインスリン分泌における意義Principal Investigator
- Principal Investigator
  
  清野進
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Chiba University
カルシウムチャネル活性化に伴う神経細胞死に関する研究
- Principal Investigator
  
  SEINO Yutaka
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
Molecular Biology and Genetics of Ion Channels in beta-cells : their roles in diabetes mellitus.Principal Investigator
- Principal Investigator
  
  SEINO Susumu
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Chiba University
Studies on the genes susceptible to non-insulin dependent diabetes mellitus in Japanese.Principal Investigator
- Principal Investigator
  
  SEINO Susumu
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  内分泌・代謝学
- Research Institution
  Chiba University School of Medicine
細胞増殖抑制におけるソマトスタチン受容体機能の役割Principal Investigator
- Principal Investigator
  
  清野進
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Chiba University
インスリン分泌とその異常におけるRab蛋白の役割Principal Investigator
- Principal Investigator
  
  清野進
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Chiba University
ソマトスタチンによる細胞増殖抑制の分子機構Principal Investigator
- Principal Investigator
  
  清野進
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Chiba University
Molecular Biological Studies of Calcium Signaling in Insulin Secretion ; their implication for the development of diabetes mellitusPrincipal Investigator
- Principal Investigator
  
  SEINO Susumu
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  内分泌・代謝学
- Research Institution
  Chiba University
Development of various somatostatin analogs for the treatment and diagnosis of tumors utilizing somatostatin receptor genesPrincipal Investigator
- Principal Investigator
  
  SEINO Susumu
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  内分泌・代謝学
- Research Institution
  Chiba University
CLONING OF T-TYPE CALCIUM CHANNEL GENE
- Principal Investigator
  
  GONOI Tohru
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  CHIBA UNIVERSITY

[Book] International Textbook of Diabetes Mellitus, 4th edition2015
- Author(s)
  Seino S, Shibasaki T, Minami K
- Publisher
  Wiley Blackwell
- Data Source
  KAKENHI-PROJECT-24229007
[Book] Annual Review 2015 糖尿病・代謝・内分泌2015
- Author(s)
  髙橋晴美、高橋利匡、柴崎忠雄、清野　進
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-24229007
[Book] Annual Review 2015糖尿病・代謝・内分泌2015
- Author(s)
  髙橋晴美、高橋利匡、柴崎忠雄、清野　進
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-24229007
[Book] 糖尿病学2015
- Author(s)
  菅原健二、清野　進.
- Publisher
  西村書店
- Data Source
  KAKENHI-PROJECT-24229007
[Book] インクレチンインパクト2014
- Author(s)
  矢部大介、岩崎真宏、清野裕
- Publisher
  日経メディカル開発
- Data Source
  KAKENHI-PROJECT-24229007
[Book] 糖尿病学イラストレイテッド発症機序・病態と治療薬の作用機序（分担：インスリン分泌と作用の基本的分子機構）2012
- Author(s)
  柴崎忠雄、清野　進
- Total Pages
  309
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-24229007
[Book] 日本の未来を拓く医療－治療医学から先制医療へ－（分担：メタボローム）2012
- Author(s)
  清野進、横井伯英
- Total Pages
  200
- Publisher
  診断と治療社
- Data Source
  KAKENHI-PROJECT-24229007
[Book] Annual Review糖尿病・代謝・内分泌（分担：糖尿病　基礎分野での進歩膵β細胞におけるEpac2Aの役割）2012
- Author(s)
  高橋晴美、柴崎忠雄、清野進
- Total Pages
  240
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-24229007
[Book] PKA-independent mechanism of cAMP in insulin secretion. Pancreatic Beta Cell in Health and Disease. Seino S and Bell GI (eds.)2008
- Author(s)
  Seino S, et al. (分担執筆)
- Publisher
  springer
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Book] Pancreatic beta cell in health and disease 編者名:Seomo, S and Bell, G(PKA-independent mcchanism of cAMP in insulin secretion)2007
- Author(s)
  Seino, S, et. al. (分担執筆)
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-15002002
[Book] Kir6.1, Kir6.2 NC-IUPHAR subcommittee on potassium channels: Kir Group. The IUPHAR Compendium of Voltage-gated Ion Channels 2005. Catterall WA, Chandy KG, and Gutman GA(eds. )2005
- Author(s)
  Seino S (分担執筆)
- Publisher
  IUPHAR Media
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] Tumor-like features of gene expression and metabolic profiles in enlarged pancreatic islets are associated with impaired incretin-induced insulin secretion in obese diabetes: a study of ZFDM rat.2020
- Author(s)
  Hayami T, Yokoi N, Yamaguchi T, Honda K, Murao N, Takahashi H, Wang S, Seino Y, Kamiya H, Yabe D, Sweet IR, Mizoguchi A, Nakamura J, Seino S
- Journal Title
  
  J Diabetes Investig
  
  Volume: - Issue: 6 Pages: 1434-1447
- DOI
  10.1111/jdi.13272
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07400, KAKENHI-PROJECT-19K09026, KAKENHI-PROJECT-18H02364, KAKENHI-PROJECT-18H02864, KAKENHI-PROJECT-17K09825, KAKENHI-PROJECT-17K09831, KAKENHI-PROJECT-19K09990
[Journal Article] Braving the element: pancreatic beta-cell dysfunction and adaptation in response to inorganic arsenic exposure (invited review)2019
- Author(s)
  Carmean CM and Seino S
- Journal Title
  
  Frontiers in Endocrinology
  
  Volume: 印刷中
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16F16418
[Journal Article] Braving the Element: Pancreatic β-Cell Dysfunction and Adaptation in Response to Arsenic Exposure.2019
- Author(s)
  Carmean CM, Seino S
- Journal Title
  
  Front Endocrinol (Lausanne)
  
  Volume: 10 Pages: 344-344
- DOI
  10.3389/fendo.2019.00344
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02864
[Journal Article] Glutamate as intracellular and extracellular signals in pancreatic islet functions2019
- Author(s)
  Takahashi H, Yokoi N, Seino S
- Journal Title
  
  Proceedings of the Japan Academy, Series B
  
  Volume: 95 Issue: 6 Pages: 246-260
- DOI
  10.2183/pjab.95.017
- NAID
  130007662352
- ISSN
  0386-2208, 1349-2896
- Year and Date
  2019-06-11
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07400, KAKENHI-PROJECT-19K09026, KAKENHI-PROJECT-18H02364, KAKENHI-PROJECT-18H02864
[Journal Article] Glucose stimulates somatostatin secretion in pancreatic δ-cells by cAMP-dependent intracellular Ca2+ release.2019
- Author(s)
  Denwood G, Tarasov A, Salehi A, Vergari E, Ramracheya R, Takahashi H, Nikolaev VO, Seino S, Gribble F, Reimann F, Rorsman P, Zhang Q
- Journal Title
  
  J Gen Physiol
  
  Volume: 151(9) Issue: 9 Pages: 1094-1115
- DOI
  10.1085/jgp.201912351
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07400, KAKENHI-PROJECT-19K09026, KAKENHI-PROJECT-18H02864
[Journal Article] Arsenic modifies serotonin metabolism through glucuronidation in pancreatic beta-cells2019
- Author(s)
  Carmean CM, Yokoi N, Takahashi H, Oduori OS, Kang C, Kanagawa A, Kirkley AG, Han G, Landeche M, Hidaka S, Katoh M, Sargis RM, Seino S
- Journal Title
  
  American Journal of Physiology Endocrinology and Metabolism
  
  Volume: 316
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16F16418
[Journal Article] Arsenic modifies serotonin metabolism through glucuronidation in pancreatic β-cells2019
- Author(s)
  Carmean Christopher M.、Yokoi Norihide、Takahashi Harumi、Oduori Okechi S.、Kang Christie、Kanagawa Akiko、Kirkley Andrew G.、Han Guirong、Landeche Michael、Hidaka Shihomi、Katoh Miki、Sargis Robert M.、Seino Susumu
- Journal Title
  
  American Journal of Physiology-Endocrinology and Metabolism
  
  Volume: 316 Issue: 3 Pages: E464-E474
- DOI
  10.1152/ajpendo.00302.2018
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02864, KAKENHI-PROJECT-16K09749, KAKENHI-PROJECT-16K09751, KAKENHI-PROJECT-18H02364, KAKENHI-PROJECT-17K09831
[Journal Article] Functional adenosine triphosphate-sensitive potassium channel is required in high-carbohydrate diet-induced increase in β-cell mass.2019
- Author(s)
  Murase M, Seino Y, Maekawa R, Iida A, Hosokawa K, Hayami T, Tsunekawa S, Hamada Y, Yokoi N, Seino S, Hayashi Y, Arima H
- Journal Title
  
  J Diabetes Investig
  
  Volume: 10（2） Issue: 2 Pages: 238-250
- DOI
  10.1111/jdi.12907
- NAID
  120006599162
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09823, KAKENHI-PROJECT-18H02364, KAKENHI-PROJECT-18H02864, KAKENHI-PROJECT-18H03176
[Journal Article] Arsenic exposure induces glucose intolerance and alters global energy metabolism2018
- Author(s)
  Kirkley Andrew G.、Carmean Christopher M.、Ruiz Daniel、Ye Honggang、Regnier Shane M.、Poudel Ananta、Hara Manami、Kamau Wakanene、Johnson Daniel N.、Roberts Austin A.、Parsons Patrick J.、Seino Susumu、Sargis Robert M.
- Journal Title
  
  American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
  
  Volume: 314 Issue: 2 Pages: R294-R303
- DOI
  10.1152/ajpregu.00522.2016
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16F16418
[Journal Article] Somatostatin Is Only Partly Required for the Glucagonostatic Effect of Glucose but Is Necessary for the Glucagonostatic Effect of KATP Channel Blockers2018
- Author(s)
  Lai Bao-Khanh、Chae Heeyoung、G?mez-Ruiz Ana、Cheng Panpan、Gallo Paola、Antoine Nancy、Beauloye Christophe、Jonas Jean-Christophe、Seghers Victor、Seino Susumu、Gilon Patrick
- Journal Title
  
  Diabetes
  
  Volume: 67 Issue: 11 Pages: 2239-2253
- DOI
  10.2337/db17-0880
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02864
[Journal Article] Ectopic overexpression of Kir6.1 in the mouse heart impacts on the life expectancy2018
- Author(s)
  Watanabe Yasuhiro、Kishimoto Takashi、Miki Takashi、Seino Susumu、Nakaya Haruaki、Matsumoto Akio
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 11723-11723
- DOI
  10.1038/s41598-018-30175-5
- NAID
  120006501223
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02864, KAKENHI-PROJECT-16K08520
[Journal Article] Impaired glucagon secretion in patients with fulminant type 1 diabetes mellitus2018
- Author(s)
  Komada Hisako、Hirota Yushi、Sakaguchi Kazuhiko、Okuno Yoko、Ogawa Wataru、Seino Susumu
- Journal Title
  
  Endocrine
  
  Volume: 63 Issue: 3 Pages: 476-479
- DOI
  10.1007/s12020-018-1750-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02864
[Journal Article] Activation of GLP-1 receptor signaling alleviates cellular stresses and improves beta cell function in a mouse model of Wolfram syndrome.2018
- Author(s)
  Kondo M, Tanabe K, Amo-Shiinoki K, Hatanaka M, Morii T, Takahashi H, Seino S, Yamada Y, Tanizawa Y
- Journal Title
  
  Diabetologia
  
  Volume: 61 Issue: 10 Pages: 2189-2201
- DOI
  10.1007/s00125-018-4679-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08516, KAKENHI-PROJECT-18H02864, KAKENHI-PROJECT-16K09749, KAKENHI-PROJECT-16K09752
[Journal Article] Inhibition of SNAT5 Induces Incretin-Responsive State From Incretin-Unresponsive State in Pancreatic β-Cells: Study of β-Cell Spheroid Clusters as a Model2018
- Author(s)
  Hashim Mahira、Yokoi Norihide、Takahashi Harumi、Gheni Ghupurjan、Okechi Oduori S.、Hayami Tomohide、Murao Naoya、Hidaka Shihomi、Minami Kohtaro、Mizoguchi Akira、Seino Susumu
- Journal Title
  
  Diabetes
  
  Volume: 67 Issue: 9 Pages: 1795-1806
- DOI
  10.2337/db17-1486
- NAID
  40022150466
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09831, KAKENHI-PROJECT-18H02364, KAKENHI-PROJECT-18H02864, KAKENHI-PROJECT-16K09749, KAKENHI-PROJECT-16K09751
[Journal Article] Effects of DPP-4 inhibitor linagliptin and GLP-1 receptor agonist liraglutide on physiological response to hypoglycaemia in Japanese subjects with type 2 diabetes: a randomized, open-label, 2-arm parallel comparative, exploratory trial2017
- Author(s)
  Yabe D, Eto T, Shiramoto M, Irie S, Murotani K, Seino Y, Kuwata H, Kurose T, Seino S, Ahren B, Seino Y
- Journal Title
  
  Diabetes Obes Metab
  
  Volume: 19 Issue: 3 Pages: 442-447
- DOI
  10.1111/dom.12817
- NAID
  120006382333
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24229007
[Journal Article] SGLT2 inhibitor use and dietary carbohydrate intake in Japanese individuals with type 2 diabetes: a randomized, open-label, 3-arm parallel comparative exploratory study2017
- Author(s)
  Yabe D, Iwasaki M, Kuwata H, Haraguchi T, Hamamoto Y, Kurose T, Sumita K, Yamazato H, Kanda S, Seino Y
- Journal Title
  
  Diabetes Obes Metab
  
  Volume: 19 Issue: 5 Pages: 739-743
- DOI
  10.1111/dom.12848
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24229007, KAKENHI-PROJECT-17K09825
[Journal Article] メタボロミクスを用いた糖尿病研究‐インクレチン作用メカニズムの解明と糖尿病バイオマーカーの探索を例に2017
- Author(s)
  横井伯英、清野　進
- Journal Title
  
  実験医学
  
  Volume: 35 Pages: 346-351
- Data Source
  KAKENHI-PROJECT-24229007
[Journal Article] β-cell signaling and insulin secretagogues: a path for improved diabetes therapy2017
- Author(s)
  Seino S, Sugawara K, Yokoi N, Takahashi H
- Journal Title
  
  Diabetes Obes Metab
  
  Volume: 印刷中 Issue: S1 Pages: 22-29
- DOI
  10.1111/dom.12995
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24229007, KAKENHI-PROJECT-16K09749, KAKENHI-PROJECT-16K09751, KAKENHI-PROJECT-17K09831, KAKENHI-PROJECT-16K19537, KAKENHI-PROJECT-15K06800, KAKENHI-PROJECT-15K08176
[Journal Article] Epac2a-null mice exhibit obesity-prone nature more susceptible to leptin resistance2017
- Author(s)
  Hwang M, Go Y, Park JH, Shin SK, Song SE, Oh BC, Im SS, Hwang I, Jeon YH, Lee IK, Seino S, Song DK
- Journal Title
  
  Int J Obes (Lond)
  
  Volume: 41 Issue: 2 Pages: 279-288
- DOI
  10.1038/ijo.2016.208
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24229007
[Journal Article] 膵β細胞に対するインクレチン作用に関する新たな知見2016
- Author(s)
  横井伯英、清野　進
- Journal Title
  
  Bio Clinica
  
  Volume: 31 Pages: 687-691
- Data Source
  KAKENHI-PROJECT-24229007
[Journal Article] Meal sequence and glucose excursion, gastric emptying and incretin secretion in type 2 diabetes: A randomized, controlled cross-over, exploratory trial.2016
- Author(s)
  Kuwata H, Iwasaki M, Shimizu S, Minami K, Maeda H, Seino S, Nakada K, Nosaka C, Murotani K, Kurose T, Seino Y, Yabe D.
- Journal Title
  
  Diabetologia
  
  Volume: 59 Issue: 3 Pages: 453-461
- DOI
  10.1007/s00125-015-3841-z
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25860748, KAKENHI-PROJECT-24229007
[Journal Article] Insulin secretory defect and insulin resistance in isolated impaired fasting glucose and isolated impaired glucose tolerance2016
- Author(s)
  Sasabe S.A., Fukushima, M, Xin X, Taniguchi A, Nakai Y, Mitsui R, Takahashi Y, Tsuji H, Yabe D, Yasuda K, Kurose, T, Inagaki N, Seino Y
- Journal Title
  
  J Diabetes Res
  
  Volume: 2016 Pages: 1298601-1298601
- DOI
  10.1155/2016/1298601
- NAID
  120005745643
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24229007, KAKENHI-PROJECT-25460657
[Journal Article] A novel diphenylthiosemicarbazide is a potential insulin secretagogue for anti-diabetic agent2016
- Author(s)
  Sugawara k, Honda K, Reien Y, Yokoi N, Seki C, Takahashi H, Minami K, Mori I, Matsumoto A, Nakaya H, Seino S
- Journal Title
  
  PLoS One
  
  Volume: 11 Issue: 10 Pages: e0164785-e0164785
- DOI
  10.1371/journal.pone.0164785
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24229007, KAKENHI-PROJECT-26460334, KAKENHI-PROJECT-15K06800, KAKENHI-PROJECT-15K08176, KAKENHI-PROJECT-16K09749, KAKENHI-PROJECT-16K15315, KAKENHI-PROJECT-16K19537
[Journal Article] 食後血糖と栄養素摂取の順番2016
- Author(s)
  矢部大介、桑田仁司、清野　裕
- Journal Title
  
  糖尿病59:30-32, 2016
  
  Volume: 59 Pages: 30-32
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24229007
[Journal Article] Type 2 diabetes via β-cell dysfunction in east Asian people.2016
- Author(s)
  Yabe D, Seino Y.
- Journal Title
  
  Lancet Diabetes Endocrinol
  
  Volume: 4 Issue: 1 Pages: 2-3
- DOI
  10.1016/s2213-8587(15)00389-7
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25860748, KAKENHI-PROJECT-24229007
[Journal Article] Beta-cell gulutamate signaling: Its role in incretin-induced insulin secretion.2016
- Author(s)
  Yokoi N, Gheni G, Takahashi H, Seino S
- Journal Title
  
  J Diabet Investig
  
  Volume: 7 Issue: S1 Pages: 38-43
- DOI
  10.1111/jdi.12468
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K06800, KAKENHI-PROJECT-24229007, KAKENHI-PROJECT-25461351, KAKENHI-PROJECT-15K08176, KAKENHI-PROJECT-16K09749
[Journal Article] インクレチンの膵作用：ホルモン分泌と細胞量の調節2016
- Author(s)
  横井伯英、清野進
- Journal Title
  
  最新医学
  
  Volume: 71 Pages: 17-22
- Data Source
  KAKENHI-PROJECT-24229007
[Journal Article] Incretin-based drugs for type 2 diabetes: Focus on East Asian perspectives2016
- Author(s)
  Seino Y, Kuwata H, Yabe D
- Journal Title
  
  J Diabetes Investig
  
  Volume: 7 Issue: S1 Pages: 102-109
- DOI
  10.1111/jdi.12490
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24229007, KAKENHI-PROJECT-25860748
[Journal Article] Alogliptin for the treatment of type 2 diabetes: a drug safety evaluation2016
- Author(s)
  Yabe D, Seino Y
- Journal Title
  
  Expert Opin Drug Saf
  
  Volume: 15 Issue: 2 Pages: 249-264
- DOI
  10.1517/14740338.2016.1125467
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24229007
[Journal Article] Role of Epac2A/Rap1 Signaling in Interplay Between Incretin and Sulfonylurea in Insulin Secretion.2015
- Author(s)
  Takahashi H, Shibasaki T, Park JH, Hidaka S, Takahashi T, Ono A, Song DK, Seino S.
- Journal Title
  
  Diabetes
  
  Volume: 64 Issue: 4 Pages: 1262-1272
- DOI
  10.2337/db14-0576
- NAID
  40020753234
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24590320, KAKENHI-PROJECT-25461351, KAKENHI-PROJECT-24229007
[Journal Article] バイオマーカー2015
- Author(s)
  横井伯英、清野　進
- Journal Title
  
  実験医学
  
  Volume: 33 Pages: 1173-1177
- Data Source
  KAKENHI-PROJECT-24229007
[Journal Article] バイオマーカー2015
- Author(s)
  横井伯英、清野　進
- Journal Title
  
  実験医学 2015年4月増刊号「先制医療へ向かう医学研究」
  
  Volume: 33 Pages: 1173-1177
- Data Source
  KAKENHI-PROJECT-24229007
[Journal Article] Compensatory hyperinsulinemia in high-fat diet-induced obese mice is associated with enhanced insulin translation in islets2015
- Author(s)
  Kanno A, Asahara SI, Masuda K, Matsuda T, Kimura-Koyanagi M, Seino S, Ogawa W, Kido Y
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 458 Issue: 3 Pages: 681-686
- DOI
  10.1016/j.bbrc.2015.02.024
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24229007, KAKENHI-PROJECT-26461382, KAKENHI-PROJECT-25461352
[Journal Article] 糖尿病と先制医療2015
- Author(s)
  福島　光夫、雀部　沙絵、清野　進
- Journal Title
  
  実験医学
  
  Volume: 33 Pages: 1049-1056
- Data Source
  KAKENHI-PROJECT-24229007
[Journal Article] Structure and functional roles of Epac2 (Rapgef4)2015
- Author(s)
  Sugawara K, Shibasaki T, Takahashi H, Seino S
- Journal Title
  
  Gene
  
  Volume: 505 Issue: 2 Pages: 577-583
- DOI
  10.1016/j.gene.2015.09.029
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08176, KAKENHI-PROJECT-25461351, KAKENHI-PROJECT-25860749, KAKENHI-PROJECT-24229007, KAKENHI-PROJECT-16K09749
[Journal Article] Paternal allelic mutation at the Kcnq1 locus reduces pancreatic β cell mass via epigenetic modification of Cdkn1c.2015
- Author(s)
  Asahara S, Etoh H, Inoue H, Teruyama K, Shibutani Y, Ihara Y, Kawada Y, Bartolome A, Hashimoto N, Matsuda T, Koyanagi-Kimura M, Kanno A, Hirota Y, Hosooka T, Nagashima K, Nishimura W, Inoue H, Matsumoto M, Higgins MJ, Yasuda K, Inagaki N, Seino S, Kasuga M, Kido Y.
- Journal Title
  
  Proceedings of the National Acaddemy of Scienceof the United States of America
  
  Volume: 112(27) Issue: 27 Pages: 8332-8337
- DOI
  10.1073/pnas.1422104112
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461351, KAKENHI-PROJECT-26461382, KAKENHI-PUBLICLY-15H01373, KAKENHI-PROJECT-24229007, KAKENHI-PROJECT-15H04851, KAKENHI-PROJECT-25461346, KAKENHI-PROJECT-25461352, KAKENHI-PROJECT-26670599, KAKENHI-PROJECT-26282022
[Journal Article] SU薬　発見と開発の歴史2015
- Author(s)
  髙橋晴美、清野　進
- Journal Title
  
  Diabetes Strategy
  
  Volume: 5 Pages: 132-138
- Data Source
  KAKENHI-PROJECT-24229007
[Journal Article] インクレチン関連薬の位置づけと適正使用2015
- Author(s)
  矢部大介、清野　裕
- Journal Title
  
  医学のあゆみ
  
  Volume: 252 Pages: 591-598
- Data Source
  KAKENHI-PROJECT-24229007
[Journal Article] インスリン分泌を増強するシグナルのインタープレイとその臨床的示唆2015
- Author(s)
  高橋晴美、グプルジャン・ゲニ、清野　進
- Journal Title
  
  実験医学
  
  Volume: 33 Pages: 124-126
- Data Source
  KAKENHI-PROJECT-24229007
[Journal Article] 膵臓β細胞内インスリン顆粒動態シミュレーション・モデル2015
- Author(s)
  松本卓也、田畑直紀、玉置　久、柴崎忠雄、清野　進、須永泰弘、横田秀夫、福島光夫
- Journal Title
  
  電気学会論文誌C
  
  Volume: 135 Pages: 963-970
- NAID
  130005090618
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24229007
[Journal Article] Why are incretin-based therapies more efficient in East Asians? Perspectives from the pathophysiology of type 2 diabetes and East Asian dietary habits2015
- Author(s)
  Yabe D, Kuwata H, Iwasaki M, Seino Y
- Journal Title
  
  Eur Med J
  
  Volume: 3 Pages: 57-65
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24229007
[Journal Article] Regulation of pancreatic β cell mass by　cross-interaction between CCAAT enhancer binding protein β induced by endoplasmic reticulum stress and AMP-activated protein kinase activity.2015
- Author(s)
  Matsuda T, Takahashi H, Mieda Y, Shimizu S, Kawamoto T, Matsuura Y, Takai T, Suzuki E, Koyanagi-Kimura M, Asahara S, Bartolome A, Yokoi N, Inoue H, Ogawa W, Seino S, Kido Y
- Journal Title
  
  PLoS ONE
  
  Volume: 10 Issue: 6 Pages: e0130757-e0130757
- DOI
  10.1371/journal.pone.0130757
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461382, KAKENHI-PROJECT-24229007, KAKENHI-PROJECT-25461352
[Journal Article] Liraglutide improves pancreatic beta cell mass and function in alloxan-induced diabetic mice2015
- Author(s)
  Tamura K, Minami K, Kudo M, Iemoto K, Takahashi H, Seino S
- Journal Title
  
  PLoS One
  
  Volume: 10 Issue: 5 Pages: e0126003-e0126003
- DOI
  10.1371/journal.pone.0126003
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24229007, KAKENHI-PROJECT-25461351
[Journal Article] Identification of putative biomarkers for prediabetes by metabolome analysis of rat models of type 2 diabetes2015
- Author(s)
  Yokoi N, Beppu M, Yoshida E, Hoshikawa R, Hidaka S, Matsubara T, Shinohara M, Irino Y, Hatano N, Seino S
- Journal Title
  
  Metabolomics
  
  Volume: 印刷中 Issue: 5 Pages: 1277-1286
- DOI
  10.1007/s11306-015-0784-9
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24229007, KAKENHI-PROJECT-24500491, KAKENHI-PROJECT-26430143
[Journal Article] β Cell Dysfunction Versus Insulin Resistance in the Pathogenesis of Type 2 Diabetes in East Asians2015
- Author(s)
  Yabe D, Seino Y, Fukushima M, Seino S
- Journal Title
  
  Curr Diab Rep
  
  Volume: NA Issue: 6 Pages: 602-602
- DOI
  10.1007/s11892-015-0602-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25860748, KAKENHI-PROJECT-24229007
[Journal Article] Short-term impacts of sodium/glucose co-transporter 2 inhibitors in Japanese clinical practice: considerations for their appropriate use to avoid serious adverse events.2015
- Author(s)
  Yabe D, Nishikino R, Kaneko M, Iwasaki M, Seino Y
- Journal Title
  
  Expert Opin Drug Saf
  
  Volume: NA Issue: 6 Pages: 795-800
- DOI
  10.1517/14740338.2015.1034105
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25860748, KAKENHI-PROJECT-24229007
[Journal Article] 糖尿病における栄養管理2015
- Author(s)
  矢部大介、清野　裕
- Journal Title
  
  BIOS
  
  Volume: 20 Pages: 3-6
- Data Source
  KAKENHI-PROJECT-24229007
[Journal Article] Preferential gene expression and epigenetic memory of induced pluripotent stem cells derived from mouse pancreas2015
- Author(s)
  Nukaya, D., Minami, K., Hoshikawa, R., Yokoi, N., Seino, S.
- Journal Title
  
  Genes Cells
  
  Volume: 印刷中 Issue: 5 Pages: 367-381
- DOI
  10.1111/gtc.12227
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24500491, KAKENHI-PROJECT-24591330, KAKENHI-PROJECT-24229007
[Journal Article] Use of the Japanese health insurance claims database to assess the risk of acute pancreatitis in patients with diabetes: comparison of DPP-4 inhibitors with other oral antidiabetic drugs2015
- Author(s)
  Yabe D, Kuwata H, Kaneko M, Ito C, Nishikino R, Murorani K, Kurose T, Seino Y
- Journal Title
  
  Diabetes Obes Metab
  
  Volume: 17 Issue: 4 Pages: 430-434
- DOI
  10.1111/dom.12381
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25860748, KAKENHI-PROJECT-24229007
[Journal Article] インクレチンとスルホニル尿素薬の併用によるインスリン分泌増強におけるEpac2Aシグナルの役割2015
- Author(s)
  柴崎忠雄、高橋晴美、清野進
- Journal Title
  
  最新医学 70巻増刊号　糖尿病と合併症（前篇）
  
  Volume: 印刷中
- Data Source
  KAKENHI-PROJECT-24229007
[Journal Article] Characterization of the prediabetic state in a novel rat model of type 2 diabetes, the ZFDM rat2015
- Author(s)
  Gheni, G., Yokoi, N., Beppu, M., Yamaguchi, T., Hidaka, S., Kawabata, A., Hoshino, Y., Hoshino, M., Seino, S.
- Journal Title
  
  J. Diabetes Res.
  
  Volume: 2015 Pages: 261418-261418
- DOI
  10.1155/2015/261418
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24500491, KAKENHI-PROJECT-24229007
[Journal Article] インクレチンの膵外作用2015
- Author(s)
  矢部大介、清野裕
- Journal Title
  
  最新医学
  
  Volume: 印刷中
- Data Source
  KAKENHI-PROJECT-24229007
[Journal Article] Early phase glucagon and insulin secretory abnormalities, but not incretin secretion, are similarly responsible for hyperglycemia after ingestion of nutrients2015
- Author(s)
  Yabe D, Kuroe A, Watanabe K, Iwasaki M, Hamasaki A, Hamamoto Y, Harada N, Yamane S, Lee S, Murotani K, Deacon CF, Holst JJ, Hirano T, Inagaki N, Kurose T, Seino Y
- Journal Title
  
  J Diabetes Complications
  
  Volume: 29 Issue: 3 Pages: 413-421
- DOI
  10.1016/j.jdiacomp.2014.12.010
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25860748, KAKENHI-PROJECT-24229007, KAKENHI-PROJECT-25461344
[Journal Article] Fructose induces glucose-dependent insulinotropic polypeptide, glucagon-like peptide-1 and insulin secretion: Role of adenosine triphosphate-sensitive K+ channels2015
- Author(s)
  Seino Y, Ogata H, Maekawa R, Izumoto T, Iida A, Harada N, Miki T, Seino S, Inagaki N, Tsunekawa S, Oiso Y, Hamada Y
- Journal Title
  
  J Diabetes Investig
  
  Volume: 6 Issue: 5 Pages: 522-526
- DOI
  10.1111/jdi.12356
- NAID
  120005770745
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24229007, KAKENHI-PROJECT-25461338, KAKENHI-PROJECT-25461344, KAKENHI-PROJECT-25293051
[Journal Article] The islet and metabolism keep time2015
- Author(s)
  Thorens B, Accili D, Ahren B, Cerasi E, Seino S, Boitard C
- Journal Title
  
  Diabetes Obes Metab
  
  Volume: 17 Suppl 1 Issue: S1 Pages: 3-5
- DOI
  10.1111/dom.12547
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24229007
[Journal Article] グルタミン酸シグナリングによるインスリン分泌制御2015
- Author(s)
  グプルジャンゲニ、横井伯英、清野　進
- Journal Title
  
  実験医学
  
  Volume: 33 Pages: 1641-1647
- Data Source
  KAKENHI-PROJECT-24229007
[Journal Article] Efficacy and safety of lixisenatide in Japanese patients with type 2 diabetes mellitus inadequately controlled by sulfonylurea with or without metformin: Subanalysis of GetGoal-S2015
- Author(s)
  Onishi Y, Niemoeller E, Ikeda, Y, Takagi H, Yabe D, Seino Y
- Journal Title
  
  J Diabetes Investig
  
  Volume: 6 Issue: 2 Pages: 201-209
- DOI
  10.1111/jdi.12275
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24229007, KAKENHI-PROJECT-25860748
[Journal Article] Effects of insulin degludec and insulin glargine on day-to-day fasting plasma glucose variability in individuals with type 1 diabetes: a multicenter, randomized, crossover study2015
- Author(s)
  Nakamura T, Sakaguchi K, So A, Nakajima S, Takabe M, Komada H, Okuno Y, Hirota Y, Nakamura T, Iida K, Kajiwara M, Nagata M, Ogawa W, Seino S
- Journal Title
  
  Diabetologia
  
  Volume: 58 Issue: 9 Pages: 2013-2019
- DOI
  10.1007/s00125-015-3648-y
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24229007
[Journal Article] Glucagon-like peptide-1 receptor agonist therapeutics for total diabetes management: Assessment of composite end-points2015
- Author(s)
  Yabe D, Kuwata H, Usui R, Kurose T, Seino Y
- Journal Title
  
  Curr Med Res Opin
  
  Volume: NA Issue: 7 Pages: 1267-1270
- DOI
  10.1185/03007995.2015.1045471
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25860748, KAKENHI-PROJECT-24229007
[Journal Article] Distinct action of the alpha-glucosidase inhibitor miglitol on SGLT3, enteroendocrine cells, and GLP1 secretion2015
- Author(s)
  Lee EY, Kaneko S, Jutabha P, Zhang X, Seino S, Jomori T, Anzai N, Miki T
- Journal Title
  
  J Endocrinol
  
  Volume: 224 Issue: 3 Pages: 205-214
- DOI
  10.1530/joe-14-0555
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24229007, KAKENHI-PROJECT-25293051, KAKENHI-PROJECT-25670116
[Journal Article] 糖尿病の新しい薬物療法‐DPP-4阻害薬2014
- Author(s)
  矢部大介、清野裕
- Journal Title
  
  Vita
  
  Volume: 31 Pages: 36-40
- Data Source
  KAKENHI-PROJECT-24229007
[Journal Article] Glutamate acts as a key signal linking glucose metabolism to incretin/cAMP action to amplify insulin secretion2014
- Author(s)
  Gheni G, Ogura M, Iwasaki M, Yokoi N, Minami K, Nakayama Y, Harada K, Hastoy B, Wu X, Takahashi H, Kimura K, Matsubara T, Hoshikawa R, Hatano N, Sugawara K, Shibasaki T, Inagaki N, Bamba T, Mizoguchi A, Fukusaki E, Rorsman P, Seino S
- Journal Title
  
  Cell Rep
  
  Volume: 9 Issue: 2 Pages: 661-673
- DOI
  10.1016/j.celrep.2014.09.030
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24229007, KAKENHI-PROJECT-24500491, KAKENHI-PROJECT-24590320, KAKENHI-PROJECT-24591330, KAKENHI-PROJECT-25293210, KAKENHI-PROJECT-25461351, KAKENHI-PROJECT-25640022, KAKENHI-PROJECT-25860749, KAKENHI-PROJECT-26430143
[Journal Article] DPP-4阻害薬、GLP-1受容体作動薬の安全性と懸念されている問題点2014
- Author(s)
  矢部大介、清野裕
- Journal Title
  
  内科
  
  Volume: 113 Pages: 97-100
- Data Source
  KAKENHI-PROJECT-24229007
[Journal Article] インスリン分泌促進薬の作用メカニズム2014
- Author(s)
  菅原健二、清野　進
- Journal Title
  
  Diabetes Frontier
  
  Volume: 25 Pages: 556-562
- Data Source
  KAKENHI-PROJECT-24229007
[Journal Article] インクレチン‐生理学、病態生理学、そして臨床医学への展開‐2014
- Author(s)
  清野　裕、山田祐一郎、稲垣暢也、清野　進
- Journal Title
  
  最新医学
  
  Volume: 69
- Data Source
  KAKENHI-PROJECT-24229007
[Journal Article] BARP suppresses voltage-gated calcium channel activity and Ca2+-evoked exocytosis2014
- Author(s)
  Beguin P, Nagashima K, Mahalakshmi RN, Vigot R, Matsunaga A, Miki T, Ng MY, Ng YJ, Lim CH, Tay HS, Hwang LA, Firsov D, Tang BL, Inagaki N, Mori Y, Seino S, Launey T, Hunziker W
- Journal Title
  
  J Cell Biol
  
  Volume: 205 Issue: 2 Pages: 233-249
- DOI
  10.1083/jcb.201304101
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24229007, KAKENHI-PROJECT-25293210, KAKENHI-PROJECT-25461346, KAKENHI-PLANNED-26111004
[Journal Article] The mind and the belly: a glance at how the nervous system directs metabolism2014
- Author(s)
  Accili D, Ahren B, Boitard C, Seino S, Thorens B, Cerasi E
- Journal Title
  
  Diabetes Obes Metab
  
  Volume: 16 Suppl 1 Issue: S1 Pages: 1-3
- DOI
  10.1111/dom.12353
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24229007
[Journal Article] KATP channel as well as SGLT1 participates in GIP secretion in the diabetic state2014
- Author(s)
  Ogata H, Seino Y, Harada N, Iida A, Suzuki K, Izumoto T, Ishikawa K, Uenishi E, Ozaki N, Hayashi Y, Miki T, Inagaki N, Tsunekawa S, Hamada Y, Seino S, Oiso Y
- Journal Title
  
  J Endocrinol
  
  Volume: 222 Issue: 2 Pages: 191-200
- DOI
  10.1530/joe-14-0161
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24229007, KAKENHI-PROJECT-24659451, KAKENHI-PUBLICLY-25122708, KAKENHI-PROJECT-25293051, KAKENHI-PROJECT-25461338, KAKENHI-PROJECT-25461344, KAKENHI-PROJECT-25670116
[Journal Article] Factors influencing durability of the glucose-lowering effect of sitagliptin combined with a sulfonylurea2014
- Author(s)
  Kubota A, Yabe D, Kanamori A, Kuroe A, Takahashi N, Saito T, Matsuba I, Nabe K, Kurose T, Seino Y
- Journal Title
  
  J Diabetes Investig
  
  Volume: 5 Issue: 4 Pages: 445-448
- DOI
  10.1111/jdi.12182
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24229007, KAKENHI-PROJECT-25860748
[Journal Article] Cooperation between cAMP signaling and sulfonylurea in insulin secretion2014
- Author(s)
  Shibasaki T, Takahashi T, Takahashi H, Seino S
- Journal Title
  
  Diabetes Obes Metab
  
  Volume: 16 Suppl 1 Issue: S1 Pages: 118-125
- DOI
  10.1111/dom.12343
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24229007, KAKENHI-PROJECT-24590320
[Journal Article] Relationship and factors responsible for regulating fasting and post-challenge plasma glucose levels in the early stage development of type 2 diabetes mellitus2014
- Author(s)
  Aoyama-Sasabe S, Xin X, Taniguchi A, Nakai Y, Mitsui R, Tsuji H, Yabe D, Yasuda K, Kurose, T, Inagaki N, Seino Y, Fukushima, M
- Journal Title
  
  J Diabetes Investig
  
  Volume: 5 Issue: 6 Pages: 663-670
- DOI
  10.1111/jdi.12239
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24229007, KAKENHI-PROJECT-25860748
[Journal Article] Postprandial serum C-peptide to plasma glucose concentration ratio correlates with oral glucose tolerance test- and glucose clamp-based disposition indexes.2013
- Author(s)
  Okuno Y, Komada H, Sakaguchi K, Nakamura T, Hashimoto N, Hirota Y, Ogawa W, Seino S
- Journal Title
  
  Metabolism
  
  Volume: 62 Issue: 10 Pages: 1470-1476
- DOI
  10.1016/j.metabol.2013.05.022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24229007
[Journal Article] A novel rat model of type 2 diabetes: the Zucker Fatty Diabetes Mellitus ZFDM rat.2013
- Author(s)
  Yokoi N., Hoshino, M., Hidaka, S., Yoshida, E., Beppu, M., Hoshikawa, R., Sudo, K., Kawada, A., Takagi, S., Seino, S.
- Journal Title
  
  J Diabetes Res
  
  Volume: Article ID 103731 Pages: 1-9
- DOI
  10.1155/2013/103731
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24229007, KAKENHI-PROJECT-24500491
[Journal Article] Antidiabetic Sulfonylureas and cAMP cooperatively activate Epac2A.2013
- Author(s)
  Takahashi T, Shibasaki T, Takahashi H, Sugawara K, Ono A, Inoue N, Furuya T, Seino S
- Journal Title
  
  Sci Signal
  
  Volume: 6 Issue: 298
- DOI
  10.1126/scisignal.2004581
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24229007, KAKENHI-PROJECT-24590320, KAKENHI-PROJECT-25461351, KAKENHI-PROJECT-25860749
[Journal Article] Current status of regeneration of pancreatic β-cells.2013
- Author(s)
  Minami K and Seino S
- Journal Title
  
  J Diabetes Investig
  
  Volume: 4 Pages: 131-141
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24229007
[Journal Article] Conditional hypovascularization and hypoxia in islets does not overtly influence adult beta cell mass and function.2013
- Author(s)
  D’Hoker J, De Leu N, Heremans Y, Baeyens L, Minami K, Ying C, Lavens A, Chintinne M, Stange G, Magenheim J, Swisa A, Martens G, Pipeleers D, van de Casteele M, Seino S, Keshet E, Dor Y, Himberg H
- Journal Title
  
  Diabetes
  
  Volume: 62 Issue: 12 Pages: 4165-4173
- DOI
  10.2337/db12-1827
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24229007, KAKENHI-PROJECT-24591330
[Journal Article] GLP-1 receptor activation and Epac2 link atrial natriuretic peptide secretion to control of blood pressure.2013
- Author(s)
  Kim M, Platt M, Shibasaki T, Quaggin S, Backx P, H, Seino S, Simpson J, Drucker DJ
- Journal Title
  
  Nat Med
  
  Volume: 19 Issue: 5 Pages: 567-575
- DOI
  10.1038/nm.3128
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24229007, KAKENHI-PROJECT-24590320
[Journal Article] Current status of regeneration of pancreatic beta-cells.2013
- Author(s)
  Minami K, Seino S
- Journal Title
  
  J Diabetes Invest
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24229007
[Journal Article] Cephalic phase insulin secretion is KATP channel-independent.2013
- Author(s)
  Seino, Y., Miki, M., Fujimoto, W., Lee, EY., Takahashi, Y., Minami, K., Oiso, Y., Seino, S.
- Journal Title
  
  J Endocrinol
  
  Volume: 218 Issue: 1 Pages: 25-33
- DOI
  10.1530/joe-12-0579
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23700900, KAKENHI-PROJECT-24229007, KAKENHI-PROJECT-25293051, KAKENHI-PROJECT-25670116
[Journal Article] Actin dynamics regulated by the balance of neuronal wiskott-aldrich syndrome protein (N-WASP) and cofilin activities detelmines the biphasic response of glucose-induced insulin secretion2013
- Author(s)
  Uenishi E, Shibasaki T, Takahashi H, Seki C, Hamaguchi H, Yasuda T, Tatebe M, Oiso, Y, Takenawa T, Seino S.
- Journal Title
  
  The Journal of Biological Chemistry
  
  Volume: 288 Issue: 36 Pages: 25851-25864
- DOI
  10.1074/jbc.m113.464420
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J02766, KAKENHI-PROJECT-23227005, KAKENHI-PROJECT-24229007, KAKENHI-PROJECT-24590320, KAKENHI-PROJECT-25461351
[Journal Article] 膵島におけるGLP-1受容体シグナルとその異常2013
- Author(s)
  髙橋晴美、清野進
- Journal Title
  
  Diabetes Frontier
  
  Volume: 26 Pages: 655-662
- Data Source
  KAKENHI-PROJECT-24229007
[Journal Article] アクチンダイナミクスによるインスリン分泌の制御機構2013
- Author(s)
  柴崎忠雄、清野　進
- Journal Title
  
  Diabetes Frontier
  
  Volume: 24 Pages: 502-506
- Data Source
  KAKENHI-PROJECT-24229007
[Journal Article] Shifting the paradigm of islet inflammation – good guy or bad guy?2013
- Author(s)
  Ahren B, Accili D, Boitard C, Cerasi E, Thoresn B, Seino S
- Journal Title
  
  Diabetes Obes Metab
  
  Volume: 11（Suppl 3） Pages: 4-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24229007
[Journal Article] 膵β細胞におけるcAMP情報伝達系、Epac2Aの役割2013
- Author(s)
  柴崎忠雄、清野　進
- Journal Title
  
  Islet Equality
  
  Volume: 2 Pages: 19-22
- Data Source
  KAKENHI-PROJECT-24229007
[Journal Article] Treating Diabetes today : a matter of selectivity of sulfonylureas2012
- Author(s)
  Seino S, et al
- Journal Title
  
  Diabetes Obes Metab
  
  Volume: 14 Issue: s1 Pages: 9-13
- DOI
  10.1111/j.1463-1326.2011.01507.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249057, KAKENHI-PROJECT-21590308, KAKENHI-PROJECT-22790860
[Journal Article] K-ATP channels in dopamine substantia nigra neurons control bursting and novelty-induced exploration.2012
- Author(s)
  Schiemann J, Schlaudraff F, Klose V, Bingmer M, Seino S, Magill PJ, Zaghloul KA, Schneider G, Liss B, Roeper J
- Journal Title
  
  Nat Neurosci
  
  Volume: 15 Issue: 9 Pages: 1272-1280
- DOI
  10.1038/nn.3185
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24229007
[Journal Article] A novel function of Noc2 in agonist-induced intracellular Ca2+ increase during zymogen-granule exocytosis in pancreatic acinar cells.2012
- Author(s)
  Ogata, S., Miki, T., Seino, S., Tamai, S., Kasai, H. & Nemoto, T.
- Journal Title
  
  PLoS ONE
  
  Volume: e37048 Issue: 5 Pages: 1-9
- DOI
  10.1371/journal.pone.0037048
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21000009, KAKENHI-PROJECT-22300131, KAKENHI-PROJECT-22590970, KAKENHI-PROJECT-24229007, KAKENHI-PLANNED-22113005
[Journal Article] Treating diabetes today : a matter of selectivity of sulphonylureas2012
- Author(s)
  Seino S, Takahashi H, Takahashi T, Shibasaki T
- Journal Title
  
  Diabetes Obes Metab
  
  Volume: 14 Pages: 9-13
- Data Source
  KAKENHI-PROJECT-21249057
[Journal Article] Variations with modest effects have an important role in the genetic background of type 2 diabetes and diabetes-related traits2012
- Author(s)
  Fujita H, Hara K, Kadowaki T
- Journal Title
  
  J Hum Genet
  
  Volume: 57 Issue: 12 Pages: 776-779
- DOI
  10.1038/jhg.2012.110
- NAID
  10031145885
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20229008, KAKENHI-PROJECT-22790862, KAKENHI-PROJECT-24229007, KAKENHI-PROJECT-24510276
[Journal Article] C-peptide response to glucagon challenge predicts improvement by liraglutide of both early insulin secretion and glucose tolerance2012
- Author(s)
  Takabe M, Matsuda T, Hirota Y, Hashimoto N, Nakamura T, Sakaguchi K, Ogawa W, Seino S
- Journal Title
  
  Diabetes Res Clin Pract
  
  Volume: Epub ahead of print Issue: 3 Pages: e32-e35
- DOI
  10.1016/j.diabres.2012.09.036
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790862, KAKENHI-PROJECT-24229007
[Journal Article] DPP4 inhibitor vildagliptin preserves beta cell mass through amelioration of ER stress in C/EBPB transgenic mice.2012
- Author(s)
  Shimizu S, Hosooka T, Matsuda T, Asahara SI, Koyanagi-Kimura M, Kanno A, Bartolome A, Etoh H, Fuchita M, Teruyama K, Takahashi H, Inoue H, Mieda Y, Hashimoto N, Seino S, Kido Y
- Journal Title
  
  J Mol Endocrinol
  
  Volume: 49 Issue: 2 Pages: 125-135
- DOI
  10.1530/jme-12-0039
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24229007
[Journal Article] Cell signalling in insulin secretion: the molecular targets of ATP, cAMP and sulfonylurea.2012
- Author(s)
  Seino S
- Journal Title
  
  Diabetologia
  
  Volume: 55 Issue: 8 Pages: 2096-2108
- DOI
  10.1007/s00125-012-2562-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24229007
[Journal Article] Dynamics of insulin secretion and the clinical implications for obesity and diabetes2011
- Author(s)
  Seino S, Shibasaki T, Minami K
- Journal Title
  
  J Clin Invest
  
  Volume: 121 Pages: 2118-2125
- Data Source
  KAKENHI-PROJECT-21249057
[Journal Article] Ablation of TSC2 enhances insulin secretion by increasing the number of mitochondria through activation of mTORC12011
- Author(s)
  Koyanagi M, Asahara S, Matsuda T, Hashimoto N, Shigeyama Y, Shibutani Y, Kanno A, Fuchita M, Mikami T, Hosooka T, Inoue H, Matsumoto M, Koike M, Uchiyama Y, Noda T, Seino S, Kasuga M, Kido Y
- Journal Title
  
  PLoS One
  
  Volume: 6
- Data Source
  KAKENHI-PROJECT-21249057
[Journal Article] Dynamics of insulin secretion and the clinical implications for obesity and diabetes2011
- Author(s)
  Seino S, et al
- Journal Title
  
  J Clinical Invest
  
  Volume: 121(invited review) Issue: 6 Pages: 2118-2125
- DOI
  10.1172/jci45680
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249057, KAKENHI-PROJECT-21590308, KAKENHI-PROJECT-21591137
[Journal Article] Rim2a determines docking and priming states in insulin granule exocytosis2011
- Author(s)
  Yasuda T, Shibasaki T, Minami K, Takahashi H, Mizoguchi A, Uriu Y, Mori Y, Miyazaki J-i, Miki T, Seino S
- Journal Title
  
  Cell Metab
  
  Volume: 12 Pages: 117-129
- Data Source
  KAKENHI-PROJECT-21249057
[Journal Article] Pancreaticβ-cells are generated by neogenesis from non-β-cells after birth2011
- Author(s)
  Nakamura K, Minami K, Tamura K, Iemoto K, Miki T, Seino S
- Journal Title
  
  Biomed Res
  
  Volume: 32 Pages: 167-174
- Data Source
  KAKENHI-PROJECT-21249057
[Journal Article] In vitro generation of insulin-secreting cells from human pancreatic exocrine cells2011
- Author(s)
  Minami K, Doi R, Kawaguchi Y, Nukaya D, Hagiwara Y, Noguchi H, Matsumoto S, Seino S
- Journal Title
  
  J Diabetes Invest
  
  Volume: 2 Pages: 271-275
- Data Source
  KAKENHI-PROJECT-21249057
[Journal Article] The pancreatic β-cell signaling : toward better understanding of diabetes and its treatment.2010
- Author(s)
  Seino S, et al.
- Journal Title
  
  Proc Jpn Acad
  
  Volume: 86 Pages: 563-577
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249057
[Journal Article] Tracing phenotypic reversibility of pancreatic b-cells in vitro2010
- Author(s)
  Minami K, Miyawaki K, Hara M, Yamada S, Seino S
- Journal Title
  
  J Diabetes Invest
  
  Volume: 1 Pages: 242-251
- Data Source
  KAKENHI-PROJECT-21249057
[Journal Article] Pancreatic beta-cell signaling : toward better understanding of diabetes and its treatment2010
- Author(s)
  Seino S, Shibasaki T, Minami K
- Journal Title
  
  Proc Jpn Acad Ser B Phys Biol Sci
  
  Volume: 86 Pages: 563-577
- NAID
  130000258749
- Data Source
  KAKENHI-PROJECT-21249057
[Journal Article] Establishment of new clonal pancreatic b-cell lines(MIN6-K) useful for study of incretin/cAMP signaling2010
- Author(s)
  Iwasaki M, Minami K, Shibasaki T, Miki T, Miyazaki J-I, Seino S
- Journal Title
  
  J Diabetes Invest
  
  Volume: 1 Pages: 137-142
- Data Source
  KAKENHI-PROJECT-21249057
[Journal Article] Sulfonylurea action re-revisited.2010
- Author(s)
  Seino S, et al.
- Journal Title
  
  J Diabetes Invest
  
  Volume: 1 Pages: 37-39
- NAID
  120003238417
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249057
[Journal Article] LKB1 regulates pancreatic beta cell size, polarity, and function2009
- Author(s)
  Granot Z, Swisa A, Magenheim J, Stolovich-Rain M, Fujimoto W, Manduchi E, Miki T, Lennerz JK, Stoeckert CJ, Jr., Meyuhas O, Seino S, Permutt MA, Piwnica-Worms H, Bardeesy N, and Dor Y
- Journal Title
  
  Cell Metab
  
  Volume: 10 Pages: 296-308
- Data Source
  KAKENHI-PROJECT-21249057
[Journal Article] Niflumic acid-sensitive ion channels play an important role in the induction of glucose-stimulated insulin secretion by cyclic AMP in mice2009
- Author(s)
  Fujimoto W, Miki T, Ogura T, Zhang M, Seino Y, Satin LS, Nakaya H, Seino S
- Journal Title
  
  Diabetologia
  
  Volume: 52 Pages: 863-872
- Data Source
  KAKENHI-PROJECT-21249057
[Journal Article] Rab11 and its effector Rip11 participate in regulation of insulin granule exocytosis2009
- Author(s)
  Sugawara K, Shibasaki T, Mizoguchi A, Saito T, Seino S
- Journal Title
  
  Genes Cells
  
  Volume: 14 Pages: 445-456
- Data Source
  KAKENHI-PROJECT-21249057
[Journal Article] Roles of cAMP signalling in insulin granule exocytosis2009
- Author(s)
  Seino S, Takahashi H, Fujimoto W, Shibasaki T
- Journal Title
  
  Diabetes Obes Metab
  
  Volume: 11 Pages: 180-188
- Data Source
  KAKENHI-PROJECT-21249057
[Journal Article] Roles of cAMP signalling in insulin granule exocytosis2009
- Author(s)
  Seino S, et al.
- Journal Title
  
  Diabetes, Obesity and Metabolism 11
  
  Pages: 180-188
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249057
[Journal Article] Isx participates in the maintenance of vitamin A metabolism by regulation of β-carotene 15, 15'-monooxygenase (Bcmo1) expression2008
- Author(s)
  Seino Y, et al.
- Journal Title
  
  J Biol Chem 283
  
  Pages: 4905-4911
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] PKA-independent mechanism of cAMP in insulin secretion.2008
- Author(s)
  Seino S, Miki T, Shibasaki T
- Journal Title
  
  Pancreatic Beta Cell in Health and Disease.(Seino S and Bell GI (eds.). Springer)
  
  Pages: 133-146
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] Role of cadherin-mediated cell-cell adhesion in pancreatic exocrine-to-endocrine transdifferentiation.2008
- Author(s)
  Minami K, Okano H, Okumachi A, Seino S
- Journal Title
  
  Biol Chem 283
  
  Pages: 13753-13761
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] Pancreatic acinar-to-β cell transdifferenfiation in vitro.2008
- Author(s)
  Minami, K, seino, S
- Journal Title
  
  Front Biosci (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] Isx participates in the maintenance of vitamin A metabolism by regulation of β-carotene 15, 15'-monooxygenase (Bcmo1) expression.2008
- Author(s)
  Seino Y, Miki T, Kiyonari H, Abe T, Fujimoto W, Kimura K, Takeuchi A, Takahashi Y, Oiso Y, Iwanaga T, Seino S
- Journal Title
  
  J Biol Chem 283
  
  Pages: 4905-4911
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] K_<ATP> channel-deficient pancreatic β-cells are streptozotocin resistant because of lower GLUT2 activity.2008
- Author(s)
  Xu J, Zhang L, Chou A, Allaby T, Belanger G, Radziuk J, Jasmin BJ, Miki T, Seino S, Renaud JM
- Journal Title
  
  Am J Physiol 294
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] Identification and functional analysis of CBLB mutations in type 1 diabetes.2008
- Author(s)
  Yokoi N, Fujiwara Y, Wang HY, Kitao M, Hayashi C, Someya T, Kanamori M, Oiso Y, Tajima N, Yamada Y, Seino Y, Ikegami H, Seino S
- Journal Title
  
  Biochem Biophys Res Commun 368
  
  Pages: 37-42
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] Dmbx1 is essential in agouti-related protein action.2007
- Author(s)
  Fujimoto W, Shiuchi T, Miki T, Minokoshi Y, Takahashi Y, Takeuchi A, Kimura K, Saito M, Iwanaga T, Seino S
- Journal Title
  
  Proc Natl Acad Sci USA 104
  
  Pages: 15514-15519
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] Generation of insulin-secreting cells from pancreatic acinar cells of animal models of type 1 diabetes.2007
- Author(s)
  Okuno M, Minami K, Okumachi A, Miyawaki K, Yokoi N, Toyokuni S, Seino S
- Journal Title
  
  Am J Physiol 292
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] 膵β細胞研究と糖尿病2007
- Author(s)
  清野進(依頼執筆)
- Journal Title
  
  日本眼科学会紀要 57
  
  Pages: 171-175
- NAID
  10018327307
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] K_<ATP> channels confer survival advantage in cocaine overdose.2007
- Author(s)
  Reyes S, Kane GC, Miki T, Seino S, Terzic A
- Journal Title
  
  Mol Psychiatry 12
  
  Pages: 1060-1061
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] Suisenbou saibou no bunkan tenkan niyoru Sui β-saibou saisei no kanousei.2007
- Author(s)
  Minami K, Seino S
- Journal Title
  
  Bunshi tounyougaku no shinpo kiso kara rinsyou made-2007. (KANEHARA Co., LTD.)
  
  Pages: 22-26
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] K_<ATP> channel knockout worsens myocardial calcium stress load in vivo and impairs recovery in stunned heart.2007
- Author(s)
  Gumina RJ, O'Cochlain DF, Kurtz CE, Bast P, Pucar D, Mishra P, Miki T, Seino S, Macura S, Terzic A
- Journal Title
  
  Am J Physiol 292
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] Induction by NeuroD of the components required for regulated exocytosis.2007
- Author(s)
  Ishizuka N, Minami K, Okumachi A, Okuno M, Seino S
- Journal Title
  
  Biochem Biophys Res Commun 354
  
  Pages: 271-277
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] Suisenbou saibou no bunkan tenkan niyoru insulin bunpitsu saibou no sakusyutsu.2007
- Author(s)
  Minami K, Okuno M, Miyawaki K, Seino S
- Journal Title
  
  Tounyoubyougaku2007, (Shindan to Chiryou Co., LTD.)
  
  Pages: 84-97
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] Cellular expression of Noc2, a Rab effector protein, in endocrine and exocrine tissues in the mouse.2007
- Author(s)
  Teramae H, Fujimoto W, Seino S, Iwanaga T
- Journal Title
  
  Histochem Cell Biol 127
  
  Pages: 1-11
- NAID
  120000969656
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] Shizen hassyou ichigata tounyoubyou doubutsu no genin idenshi.2007
- Author(s)
  Yokoi N, Seino S
- Journal Title
  
  Tounyoubyougaku kiso to rinsyou. (Nishimura Co., Ltd.)
  
  Pages: 291-293
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] Essential role of Epac2/Rap1 signaling in regulation of insulin granule dynamics by cAMP.2007
- Author(s)
  Shibasaki T, Takahashi H, Miki T, Sunaga Y, Matsumura K, Yamanaka M, Zhang C, Tamamoto A, Satoh T, Miyazaki J, Seino S
- Journal Title
  
  Proc Natl Acad Sci USA 104
  
  Pages: 19333-19338
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] Geneticreconstitution of autoimmune type 1 diabetes with two major susceptibility genes in the rat.2007
- Author(s)
  Yokoi N, Hayashi C, Fujiwara Y, Wang HY, Seino S
- Journal Title
  
  Diabetes 56
  
  Pages: 506-512
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] Sui β-saibou kenkyu to tounyoubyou2007
- Author(s)
  Seino S
- Journal Title
  
  Nippon gankagakkai kiyou 57
  
  Pages: 171-175
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] K_<ATP> channel mutation confers risk for vein of Marshall adrenergic atrial fibrillation.2007
- Author(s)
  Olson TM, Alekseev AE, Moreau C, Liu XK, Zingman LV, Miki T, Seino S, Asirvatham SJ, Jahangir A, Terzic A
- Journal Title
  
  Nat Clin Pract Cardiovasc Med 4
  
  Pages: 110-116
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] Suisenbou saibou kara insulin bunpitsu saibou eno bunka tenkan.2007
- Author(s)
  Minami K, Seino S
- Journal Title
  
  Igaku no ayumi 220
  
  Pages: 1145-1148
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] Disruption of Kir6.2-containing ATP-sensitive potassium channels impairs maintenance of hypoxic gasping in mice.2007
- Author(s)
  Miyake A, Yamada K, Kosaka T, Miki T, Seino S, Inagaki N
- Journal Title
  
  Eur J Neurosci 25
  
  Pages: 2349-2363
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] Spontaneous recovery from hyperglycemia by regeneration of pancreatic β-cells in Kir6.2G132S transgenic mice.2006
- Author(s)
  Oyama K, Minami K, Ishizaki K, Fuse M, Miki T, Seino S
- Journal Title
  
  Diabetes 55
  
  Pages: 1930-1938
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] Protection conferred by myocardial ATP-sensitive K^+ channels in pressure overload-induced congestive heart failure revealed in KCNJ11 Kir6.2-null mutant.2006
- Author(s)
  Yamada S, Kane GC, Behfar A, Liu XK, Dyer RB, Faustino RS, Miki T, Seino S, Terzic A
- Journal Title
  
  J Physiol 577
  
  Pages: 1053-1065
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] Suisenbou saibou no bunka tenkan niyoru insulin bunpitsu saibou no yuudou.2006
- Author(s)
  Minami K, Seino S
- Journal Title
  
  Saishin igaku 61
  
  Pages: 1496-1501
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] cAMP shigunaru niyoru exocytosis no tyousetsu kikou2006
- Author(s)
  Shibasaki T, Seino S
- Journal Title
  
  Seitai no kagaku 57
  
  Pages: 91-95
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] Behavioral phenotyping of mice lacking the K_<ATP> channel subunit Kir6.2.2006
- Author(s)
  Deacon RM, Brook RC, Meyer D, Haeckel O, Ashcroft FM, Miki T, Seino S, Liss B
- Journal Title
  
  Physiol Behav 87
  
  Pages: 723-733
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] Association studies of variants in the genes involved in pancreatic β-cell function in type 2 diabetes in Japanese subjects.2006
- Author(s)
  Yokoi N, Kanamori M, Horikawa Y, Takeda J, Sanke T, Furuta H, Nanjo K, Mori H, Kasuga M, Hara K, Kadowaki T, Tanizawa Y, Oka Y, Iwami Y, Ohgawara H, Yamada Y, Seino Y, Yano H, Cox NJ, Seino S
- Journal Title
  
  Diabetes 55
  
  Pages: 2379-2386
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] Enhanced neuronal damage after ischemic insults in mice lacking Kir6.2-containing ATP-sensitive K^+ channels.2006
- Author(s)
  Sun HS, Feng ZP, Miki T, Seino S, French RJ
- Journal Title
  
  J Neurophysiol 95
  
  Pages: 2590-2601
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] Shigunaru jyuyou kikou no kaimei ga michibiku souyaku chiryou eno tyouyaku : shigunaru jyuyou to shikkan Sui β-saibou karano insulin bunpitsu seigyo shigunaru to sono hatan.2006
- Author(s)
  Miki T, Seino S
- Journal Title
  
  Jikken igaku 24
  
  Pages: 758-763
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] Cerebral glucose transporters expression and spatial learning in the K-ATP Kir6.2^<-/-> knockout mice.2006
- Author(s)
  Choeiri C, Staines WA, Miki T, Seino S, Renaud JM, Teutenberg K, Messier C
- Journal Title
  
  Behav Brain Res 172
  
  Pages: 233-239
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] Gene knockout of the KCNJ8-encoded Kir6.1 K_<ATP> channel imparts fatal susceptibility to endotoxemia.2006
- Author(s)
  Kane GC, Lam CF, O'Cochlain F, Hodgson DM, Reyes S, Liu XK, Miki T, Seino S, Katusic ZS, Terzic A
- Journal Title
  
  FASEB J 20
  
  Pages: 2271-2280
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] Essential role of ubiquitin-proteasome system in normal regulation of insulin secretion.2006
- Author(s)
  Kawaguchi M, Minami K, Nagashima K, Seino S
- Journal Title
  
  J Biol Chem 281
  
  Pages: 13015-13020
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] Identification and characterization of a novel member of the ATP-sensitive K^+ channel subunit family, Kir6.3, in zebrafish.2006
- Author(s)
  Zhang C, Miki T, Shibasaki T, Yokokura M, Saraya A, Seino S
- Journal Title
  
  Physiol Genomics 24
  
  Pages: 290-297
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] cAMP compartment to insulin bunpitsu.2006
- Author(s)
  Shibasaki T, Seino S
- Journal Title
  
  Bunshi tounyougaku no shinpo kiso kara rinsyou made-2006. (KANEHARA Co., LTD.)
  
  Pages: 2-7
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] KCNJ11 gene knockout of the Kir6.2 K_<ATP> channel causes maladaptive remodeling and heart failure in hypertension.2006
- Author(s)
  Kane GC, Behfar A, Dyer RB, O'Cochlain DF, Liu XK, Hodgson DM, Reyes S, Miki T, Seino S, Terzic A
- Journal Title
  
  Hum Mol Genet 15
  
  Pages: 2285-2297
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] Lineage tracing and characterization of insulin-secreting cells generated from adult pancreatic acinar cells.2005
- Author(s)
  Minami K, Okuno M, Miyawaki K, Okumachi A, Ishizaki K, Oyama K, Kawaguchi M, Ishizuka N, Iwanaga T, Seino S
- Journal Title
  
  Proc Natl Acad Sci USA 102
  
  Pages: 15116-15121
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] Possible role of PEPT1 in gastrointestinal hormone secretion.2005
- Author(s)
  Matsumura K, Miki T, Jhomori T, Gonoi T, Seino S
- Journal Title
  
  Biochem Biophys Res Commun 336
  
  Pages: 1028-1032
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] International Union of Pharmacology. LIV. Nomenclature and molecular relationships of inwardly rectifying potassium channels.2005
- Author(s)
  Kubo Y, Adelman JP, Clapham DE, Jan LY, Karschin A, Kurachi Y, Lazdunski M, Nichols CG, Seino S, Vandenberg CA
- Journal Title
  
  Pharmacol Rev 57
  
  Pages: 509-526
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] PDX-1 protein is internalized by lipid raft-dependent macropinocytosis.2005
- Author(s)
  Noguchi H, Matsumoto S, Okitsu T, Iwanaga Y, Yonekawa Y, Nagata H, Matsushita M, Wei FY, Matsui H, Minami K, Seino S, Masui Y, Futaki S, Tanaka K
- Journal Title
  
  Cell Transplant 14
  
  Pages: 637-645
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] Physical and functional interaction of noc2/rab3 in exocytosis.2005
- Author(s)
  Shibasaki T, Seino S
- Journal Title
  
  Methods Enzymol 403
  
  Pages: 408-419
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] PKA-dependent and PKA-independent pathways for cAMP-regulated exocytosis2005
- Author(s)
  Seino S, Shibasaki T)
- Journal Title
  
  Physiol Rev 85
  
  Pages: 1303-1342
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] Physical and functional interaction of noc2/rab3 in exocytosis2005
- Author(s)
  Shibasaki T, Seino S
- Journal Title
  
  Methods Enzymol 403
  
  Pages: 408-419
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] Roles of K_<ATP> channels as metabolic sensors in acute metabolic changes.2005
- Author(s)
  Miki T, Seino S
- Journal Title
  
  J Mol Cell Cardiol 38
  
  Pages: 917-925
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] K-ATP channels promote the differential degeneration of dopaminergic midbrain neurons.2005
- Author(s)
  Liss B, Haeckel O, Wildmann J, Miki T, Seino S, Roeper J
- Journal Title
  
  Nat Neurosci 8
  
  Pages: 1742-1751
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] Functional analysis of transcriptional repressor Otx3/Dmbx1.2005
- Author(s)
  Kimura K, Miki T, Shibasaki T, Zhang Y, Ogawa M, Saisho H, Okuno M, Iwanaga T, Seino S
- Journal Title
  
  FEBS Lett 579
  
  Pages: 2926-2932
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] Glucose transporter plasticity during memory processing.2005
- Author(s)
  Choeiri C, Staines W, Miki T, Seino S, Messier C
- Journal Title
  
  Neuroscience 130
  
  Pages: 591-600
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] Direct inhibition of : the interaction between α-interaction domain and β-interaction domain of voltage-dependent Ca^<2+> channels by Gem.2005
- Author(s)
  Sasaki T, Shibasaki T, Beguin P, Nagashima K, Miyazaki M, Seino S
- Journal Title
  
  J Biol Chem 280
  
  Pages: 9308-9312
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] Sui β-saibou ni okeru cAMP compartment.2005
- Author(s)
  Shibasaki T, Seino S
- Journal Title
  
  Saishin igaku 60
  
  Pages: 2649-2653
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] PKA-dependent and PKA-independent pathways for cAMP-regulated exocytosis.2005
- Author(s)
  Seino S, Shibasaki T
- Journal Title
  
  Physiol Rev 85
  
  Pages: 1303-1342
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] PKA-dependent and PKA-independent pathways for cAMP-regulated exocytosis2005
- Author(s)
  Seino S et al.
- Journal Title
  
  Physiol Rev 85・4
  
  Pages: 1303-1342
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] Role of ATP-sensitive K^+ channels in electrophysiological alterations during myocardial ischemia : a study using Kir6.2-null mice.2005
- Author(s)
  Saito T, Sato T, Miki T, Seino S, Nakaya H
- Journal Title
  
  Am J Physiol 288
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] Distinct effects of glucosedependent insulinotropic polypeptide and glucagon-like peptide-1 on insulin secretion and gut motility.2005
- Author(s)
  Miki T, Minami K, Shinozaki H, Matsumura K, Saraya A, Ikeda H, Yamada Y, Holst JJ, Seino S
- Journal Title
  
  Diabetes 54
  
  Pages: 1056-1063
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] Treadmill running causes significant fiber damage in skeletal muscle of K_<ATP> channel-deficient mice.2005
- Author(s)
  Thabet M, Miki T, Seino S, Renaud JM
- Journal Title
  
  Physiol Genomics 22
  
  Pages: 204-212
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] Kir6.1, Kir6.2 NC-IUPHAR subcommittee on potassium channels : Kir Group.2005
- Author(s)
  Seino S
- Journal Title
  
  The IUPHAR Compendium of Voltage-gated Ion Channels 2005. (Catterall WA, Chandy KG, and Gutman GA (eds.). IUPHAR Media)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] Gene targeting approach to clarification of ion channel function : studies of Kir6.x null mice.2004
- Author(s)
  Seino S, Miki T
- Journal Title
  
  J Physiol 554
  
  Pages: 295-300
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] ATP-sensitive K^+ channel knockout compromises the metabolic benefit of exercise training, resulting in cardiac deficits.2004
- Author(s)
  Kane GC, Behfar A, Yamada S, Perez-Terzic C, O'Cochlain F, Reyes S, Dzeja PP, Miki T, Seino S, Terzic A
- Journal Title
  
  Diabetes 53
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] Identification and characterization of Noc2 as a potential Rab3B effector protein in epithelial cells.2004
- Author(s)
  Manabe S, Nishimura N, Yamamoto Y, Kitamura H, Morimoto S, Imai M, Nagahiro S, Seino S, Sasaki T
- Journal Title
  
  Biochem Biophys Res Commun 316
  
  Pages: 218-225
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] Genetic disruption of Kir6.2, the pore-forming subunit of ATP-sensitive K^+ channel, predisposes to catecholamine-induced ventricular dysrhythmia.2004
- Author(s)
  Liu XK, Yamada S, Kane GC, Alekseev AE, Hodgson DM, O'Cochlain F, Jahangir A, Miki T, Seino S, Terzic A
- Journal Title
  
  Diabetes 53
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] Interaction of ATP sensor, cAMP sensor, Ca^<2+> sensor, and voltage-dependent Ca^<2+> channel in insulin granule exocytosis.2004
- Author(s)
  Shibasaki T, Sunaga Y, Fujimoto K, Kashima Y, Seino S
- Journal Title
  
  J Biol Chem 279
  
  Pages: 7956-7961
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] Roles of K_<ATP> channels as metabolic sensors in acute metabolic changes2004
- Author(s)
  Miki T, Seino S
- Journal Title
  
  J Mol Cell Cardiol 38
  
  Pages: 917-925
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] Polymorphic variation in the CBLB gene in human type 1 diabetes.2004
- Author(s)
  Kosoy R, Yokoi N, Seino S, Concannon P
- Journal Title
  
  Genes Immun 5
  
  Pages: 232-235
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] Roles of ATP-sensitive K^+ channels as metabolic sensors : studies of Kir6.x null mice.2004
- Author(s)
  Minami K, Miki T, Kadowaki T, Seino S
- Journal Title
  
  Diabetes 53
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] Noc2 is essential in normal regulation of exocytosis in endocrine and exocrine cells.2004
- Author(s)
  Matsumoto M, Miki T, Shibasaki T, Kawaguchi M, Shinozaki H, Nio J, Saraya A, Koseki H, Miyazaki M, Iwanaga T, Seino S
- Journal Title
  
  Proc Natl Acad Sci USA 101
  
  Pages: 8313-8318
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] Integration of ATP, cAMP, and Ca^<2+> signals in insulin granule exocytosis.2004
- Author(s)
  Shibasaki T, Sunaga Y, Seino S
- Journal Title
  
  Diabetes 53
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] Construction of a multi-functional cDNA library specific for mouse pancreatic islets and its application to microarray.2004
- Author(s)
  Nishimura M, Yokoi N, Miki T, Horikawa Y, Yoshioka H, Takeda J, Ohara O, Seino S
- Journal Title
  
  DNA Res 11
  
  Pages: 315-323
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] Diet-induced glucose intolerance in mice with decreased β-cell ATP-sensitive K^+ channels.2004
- Author(s)
  Remedi MS, Koster JC, Markova K, Seino S, Miki T, Patton BL, McDaniel ML, Nichols CG
- Journal Title
  
  Diabetes 53
  
  Pages: 3159-3167
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] Effects of fluoroquinolones on insulin secretion and β-cell ATP-sensitive K^+ channels.2004
- Author(s)
  Saraya A, Yokokura M, Gonoi T, Seino S
- Journal Title
  
  Eur J Pharmacol 497
  
  Pages: 111-117
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] Prediction of the coding sequences of mouse homologues of KIAA gene : IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.2004
- Author(s)
  Okazaki N, R FK, Ohara R, Inamoto S, Koseki H, Hiraoka S, Saga Y, Seino S, Nishimura M, Kaisho T, Hoshino K, Kitamura H, Nagase T, Ohara O, Koga H
- Journal Title
  
  DNA Res 11
  
  Pages: 205-218
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] Gene targeting approach to clarification of ion channel function : studies of Kir6. x null mice2004
- Author(s)
  Seino S, Miki T
- Journal Title
  
  J Physiol 554
  
  Pages: 295-300
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] Establishment and characterization of the Komeda diabetes-prone rat as a segregating inbred strain2003
- Author(s)
  Yokoi N, Namae M, Fuse M, Wang HY, Hirata T, Seino S, Komeda K
- Journal Title
  
  Exp Anim 52
  
  Pages: 295-301
- NAID
  10011713364
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] Ichigata tounyoubyou model KDP rat no shikkan kanjyusei idenshi no cloning2003
- Author(s)
  Yokoi N, Seino S
- Journal Title
  
  Igaku no ayumi 207
  
  Pages: 613-617
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] Cardioprotective effect of diazoxide is mediated by activation of sarcolemmal but not mitochondrial ATP-sensitive potassium channels in mice.2003
- Author(s)
  Suzuki M, Saito T, Sato T, Tamagawa M, Miki T, Seino S, Nakaya H
- Journal Title
  
  Circulation 107
  
  Pages: 682-685
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] Sui β-saibou niokeru glucose outousei to saibounai calcium.2003
- Author(s)
  Minami K, Yokokura M, Seino S
- Journal Title
  
  Bunshi tounyougaku no shinpo kiso kara rinsyou made-2003. (KANEHARA Co., LTD.)
  
  Pages: 17-22
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] Tokusyu : Tounyoubyou kenkyu no shintenkai insulin bunpitsu no tyousetsu kikou.2003
- Author(s)
  Minami K, Shibasaki T, Miki T, Seino S
- Journal Title
  
  Seikagaku 75
  
  Pages: 1312-1323
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] ATP-sensitive K^+ channel-mediated glucose uptake is independent of IRS-1/phosphatidylinositol 3-kinase signaling.2003
- Author(s)
  Minami K, Morita M, Saraya A, Yano H, Terauchi Y, Miki T, Kuriyama T, Kadowaki T, Seino S
- Journal Title
  
  Am J Physiol 285
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] Rat neurological disease creeping is caused by a mutation in the reelin gene.2003
- Author(s)
  Yokoi N, Namae M, Wang HY, Kojima K, Fuse M, Yasuda K, Serikawa T, Seino S, Komeda K
- Journal Title
  
  Brain Res Mol Brain Res 112
  
  Pages: 1-7
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] Systemic lupus erythematosus to Sjogren syndrome wo gappei shita ichigata tounyoubyou no ichirei.2003
- Author(s)
  Tanaka M, Miyazaki Y, Yokoi N, Seino S
- Journal Title
  
  Tounyoubyou 46
  
  Pages: 11-14
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] Knockout of Kir6.2 negates ischemic preconditioning-induced protection of myocardial energetics2003
- Author(s)
  Gumina RJ, Pucar D, Bast P, Hodgson DM, Kurtz CE, Dzeja PP, Miki T, Seino S, Terzic A
- Journal Title
  
  Am J Physiol 284
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] Tokusyu : Rinsyou ouyou no doukou to syourai eno tenbou suizou wo taisyou tosita saisei iryou.2003
- Author(s)
  Minami K, Okuno M, Miyawaki K, Seino S
- Journal Title
  
  Nippon Rinsyou 61
  
  Pages: 504-508
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] Sui β-saibou no saisei igaku.2003
- Author(s)
  Minami K, Okuno M, Seino S
- Journal Title
  
  Konnichi no isyoku 16
  
  Pages: 125-132
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] K_<ATP> channels depress force by reducing action potential amplitude in mouse EDL and soleus muscle.2003
- Author(s)
  Gong B, Legault D, Miki T, Seino S, Renaud JM
- Journal Title
  
  Am J Physiol 285
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] International Union of Pharmacology. XLI. Compendium of voltage-gated ion channels : potassium channels.2003
- Author(s)
  Gutman GA, Chandy KG, Adelman JP, Aiyar J, Bayliss DA, Clapham DE, Covarriubias M, Desir GV, Furuichi K, Ganetzky B, Garcia ML, Grissmer S, Jan LY, Karschin A, Kim D, Kuperschmidt S, Kurachi Y, Lazdunski M, Lesage F, Lester HA, McKinnon D, Nichols CG, O'Kelly I, Robbins J, Robertson GA, Rudy B, Sanguinetti M, Seino S, Stuehmer W, Tamkun MM, Vandenberg CA, Wei A, Wulff H, Wymore RS
- Journal Title
  
  Pharmacol Rev 55
  
  Pages: 583-586
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Journal Article] Involvement of Exoc31, a protein structurally related to the exocyst subunit Sec6, in insulin secretion.
- Author(s)
  Saito T, Shibasaki T, Seino S
- Journal Title
  
  Biomed Res (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Patent] 遺伝子改変動物の新規用途2004
- Inventor(s)
  清野進
- Industrial Property Rights Holder
  神戸大学
- Industrial Property Number
  2004-313063
- Filing Date
  2004-10-27
- Data Source
  KAKENHI-PROJECT-15002002
[Patent] 遺伝子改変動物の新規用途2004
- Inventor(s)
  清野進, 三木隆司, 尾山和信
- Industrial Property Rights Holder
  神戸大学, 武田薬品工業株式会社
- Industrial Property Number
  2004-313063
- Filing Date
  2004-10-27
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Patent] Noc2ノックアウトマウス2004
- Inventor(s)
  清野進, 三木隆司, 岩永俊彦, 松本正成
- Industrial Property Rights Holder
  京都大学, 日本ケミカルリサーチ
- Industrial Property Number
  2004-110374
- Filing Date
  2004-04-02
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Patent] インスリン分泌細胞の誘導2004
- Inventor(s)
  清野進, 南幸太郎, 奥野正顕, 宮脇一真
- Industrial Property Rights Holder
  京都大学, 日本ケミカルリサーチ
- Industrial Property Number
  2004-165367
- Filing Date
  2004-06-03
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Presentation] SGLT2阻害薬が全身の糖代謝に及ぼす影響の検討2020
- Author(s)
  横井伯英、高橋晴美、清野進
- Organizer
  第34回日本糖尿病・肥満動物学会年次学術集会
- Data Source
  KAKENHI-PROJECT-18H02864
[Presentation] 新規Epac2アイソフォームの同定とその膵β細胞機能における役割2020
- Author(s)
  高橋晴美、藤原結花、堰千紘、横井伯英、清野進
- Organizer
  第93回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-18H02864
[Presentation] 肥満糖尿病の膵島におけるインクレチン応答性障害の発症機序2020
- Author(s)
  速水智英、横井伯英、吉田舞、本田洸平、高橋晴美、神谷英紀、溝口明、中村二郎、清野進
- Organizer
  第34回日本糖尿病・肥満動物学会年次学術集会
- Data Source
  KAKENHI-PROJECT-18H02864
[Presentation] 膵島機能の加齢性変化の解明－B6マウスならびに老化促進モデルマウスを用いた検討－2020
- Author(s)
  村尾直哉、横井伯英、速水智英、高橋晴美、清野進
- Organizer
  第34回日本糖尿病・肥満動物学会年次学術集会
- Data Source
  KAKENHI-PROJECT-18H02864
[Presentation] Promoting function to treat diabetes- Insulin secretion.2019
- Author(s)
  Susumu Seino
- Organizer
  American Diabetes Association 79th Scientific Sessions
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02864
[Presentation] Role of glutamine/glutamate signaling in insulin secretion.2019
- Author(s)
  Guirong Han, Harumi Takahashi, Norihide Yokoi, Ghupurjan Gheni, Naoya Murao, Yutaka Seino, Yoshiyuki Hamamoto, Yoshiaki Kido, Susumu Seino
- Organizer
  The 11th Scientific Meeting of the AASD in conjunction with The 62nd Annual Meeting of the Japan Diabetes Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02864
[Presentation] Enhanced beta-cell Gq signaling underlies improved insulin secretion and glucose tolerance by GLP-1 in beta-cell-specific Kir6.2 knockout diabetic mice2019
- Author(s)
  Naoya Murao, Oduori S. Okechi, Kenju Shimomura, Harumi Takahashi, Norihide Yokoi, Susumu Seino
- Organizer
  20th Servier-IGIS Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02864
[Presentation] 会長特別企画　ヒト試料を用いた研究：　基礎研究の立場から2019
- Author(s)
  清野進
- Organizer
  第62回日本糖尿病学会年次学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02864
[Presentation] 肥満２型糖尿病における肥大膵島は未分化細胞や癌細胞に類似した代謝様式に変化し、インクレチン応答性障害を呈する2019
- Author(s)
  速水智英,　横井伯英,　本田洸平, 高橋晴美,　神谷英紀,　溝口明,　中村二郎, 　清野進
- Organizer
  第33回糖尿病・肥満動物学会
- Data Source
  KAKENHI-PROJECT-18H02864
[Presentation] How can we improve insulin secretion of diabetic-beta-cells?2019
- Author(s)
  Susumu Seino, Naoya Murao, Harumi Takahashi, Okechi S Oduori
- Organizer
  International Diabetes Federation Congress 2019
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02864
[Presentation] 肥満糖尿病における膵島機能不全の機序の解明2019
- Author(s)
  吉田舞, 横井伯英, 速水智英, 川畑綾子, 高橋晴美, 小川渉, 清野進
- Organizer
  第62回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-18H02864
[Presentation] SGLT2欠損状態における低炭水化物食摂取が耐糖能、血糖調節ホルモンに及ぼす影響の解明 -SGLT2変異SAMP10マウスを用いた検討-2019
- Author(s)
  韓桂栄、浜本芳之、横井伯英、高木貞明、細川昌則、木戸良明、清野裕、清野進
- Organizer
  第34回老化促進モデルマウス（SAM）学会学術大会
- Data Source
  KAKENHI-PROJECT-18H02864
[Presentation] 新規インスリン分泌促進薬シード化合物の同定とその作用機序の解明2019
- Author(s)
  村尾直哉、菅原健二、Okechi S Oduori、Christopher M Carmean、横井伯英、高橋晴美、清野進
- Organizer
  第62回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-18H02864
[Presentation] 膵β細胞に発現する新たなEpac2アイソフォームとその特異的な役割2019
- Author(s)
  高橋晴美、藤原結花、堰千紘、横井伯英、清野進
- Organizer
  第62回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-18H02864
[Presentation] Enhanced β-cell Gq signal underlies improved insulin secretion and glucose tolerance by GLP-1 in Kir6.2 KO diabetic mice.2019
- Author(s)
  Okechi S Oduori，Kenju Shimomura，Harumi Takahashi，Shihomi Hidaka，Naoya Murao，Norihide Yokoi，Susumu Seino
- Organizer
  第62回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-18H02864
[Presentation] Role of glutamate signaling in insulin secretion.2019
- Author(s)
  Norihide Yokoi, Harumi Takahashi, Susumu Seino
- Organizer
  第62回日本糖尿病学会年次学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02864
[Presentation] Age-associated changes of glucose tolerance and pancreatic islet function in mice.2019
- Author(s)
  Naoya Murao, Norihide Yokoi, Tomohide Hayami, Okechi S Oduori, Yingyue Quan, Harumi Takahashi, Susumu Seino
- Organizer
  International Diabetes Federation Congress 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02864
[Presentation] SGLT2欠損マウスにおける低炭水化物食摂取が耐糖能、血糖調節ホルモンおよび臓器代謝に及ぼす影響の解明2019
- Author(s)
  韓桂栄、浜本芳之、横井伯英、木戸良明、清野裕、清野進
- Organizer
  第22回日本病態栄養学会年次学術集会
- Data Source
  KAKENHI-PROJECT-18H02864
[Presentation] Elucidation of genetic factors and pathogenesis of obese diabetes: Study of ZFDM rat.2019
- Author(s)
  Norihide Yokoi, Tomohide Hayami, Mai Yoshida, Harumi Takahashi, Yukio Taniguchi, Susumu Seino
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18H02864
[Presentation] Tumor-like metabolic feature of enlarged pancreatic islets underlies incretin unresponsiveness in obese type 2 diabetes.2019
- Author(s)
  Tomohide Hayami, Norihide Yokoi, Kohei Honda, Harumi Takahashi, Hideki Kamiya, Akira Mizoguchi, Jiro Nakamura, Susumu Seino
- Organizer
  The 11th Scientific Meeting of the AASD in conjunction with The 62nd Annual Meeting of the Japan Diabetes Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02864
[Presentation] 肥満糖尿病におけるインクレチン応答性インスリン分泌障害機序の解明2018
- Author(s)
  速水智英, 横井伯英, マヒラアシム, 高橋晴美, 清野進
- Organizer
  第39回日本肥満学会
- Data Source
  KAKENHI-PROJECT-18H02864
[Presentation] The mechanism of impaired incretin responsiveness in the pancreatic islets of obese type 2 diabetes: A study of the ZFDM rat2018
- Author(s)
  Norihide Yokoi, Tomohide Hayami, Shihomi Hidaka, Ayako Kawabata, Harumi Takahashi, Susumu Seino
- Organizer
  The 54th EASD Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02864
[Presentation] SGLT2阻害状態における低炭水化物食摂取が耐糖能、血糖調節ホルモンおよび臓器代謝に及ぼす影響の解明 -SGLT2変異SAMP10マウスを用いた検討-2018
- Author(s)
  韓桂栄、浜本芳之、横井伯英、_木貞明、細川昌則、木戸良明、清野　裕、清野進
- Organizer
  第33回老化促進モデルマウス(SAM)学会学術大会
- Data Source
  KAKENHI-PROJECT-18H02864
[Presentation] GLP-1 receptor agonists and DPP-4 inhibitors both normalize diabetes caused by deletion of β-cell KATP_channels in mice2018
- Author(s)
  Oduori S. Okechi, Harumi Takahashi, Norihide Yokoi, Kohtaro Minami, Yuko Maejima, Kenju Shimomura, Susumu Seino
- Organizer
  The 61st Annual Meeting of the Japan Diabetes Society
- Data Source
  KAKENHI-PROJECT-18H02864
[Presentation] Arsenic modifies serotonin metabolism through glucuronidation in pancreatic beta-cells.2018
- Author(s)
  Carmean CM, Yokoi N, Seino S, Sergis RM
- Organizer
  American Diabetes Association's 78th Scientific Sessions
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16F16418
[Presentation] 人との出会いと私のインスリン分泌研究2018
- Author(s)
  清野　進
- Organizer
  金沢大学魁プロジェクト　Symposium on Neural Orchestration and Islet Biology
- Invited
- Data Source
  KAKENHI-PROJECT-18H02864
[Presentation] Beta-cell glutamate metabolism in insulin secretion2018
- Author(s)
  清野　進
- Organizer
  Keystone Symposia on Diabetes Mellitus-Drivers of Type 2 diabetes: From genes to environment
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02864
[Presentation] 肥満糖尿病モデルZFDMラットにおけるインクレチン作用障害の発症機序2018
- Author(s)
  横井　伯英、速水　智英、川畑　綾子、星野　貴一、星野　雅行、清野　進
- Organizer
  第140回関西実験動物研究会
- Data Source
  KAKENHI-PROJECT-18H02864
[Presentation] グルタミン-グルタミン酸シグナルによるインスリン分泌増強機構の解明2018
- Author(s)
  韓　桂栄、横井　伯英　グプルジャン　ゲニ、村尾　直哉、高橋晴美、清野　裕、木戸　良明、清野　進
- Organizer
  第61回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-18H02864
[Presentation] 肥満2型糖尿病では肥大した膵島における糖代謝異常とO-GlcNAc化の亢進がインクレチン応答性インスリン分泌障害を引き起こす2018
- Author(s)
  横井　伯英、速水　智英、吉田　舞、高橋　晴美、清野　進
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18H02864
[Presentation] 肥満糖尿病の膵島におけるインクレチン応答性障害-オミクス解析による検討-2018
- Author(s)
  速水智英, 横井伯英, 日高志保美, 川畑綾子, グプルジャンゲニ, マヒラアシム, 高橋晴美, 神谷英紀, 清野裕, 中村二郎, 清野進
- Organizer
  61回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-18H02864
[Presentation] Knockdown of arsenic-induced genes recovers pancreatic beta-cells from arsenic-associated functional defects2018
- Author(s)
  Carmean CM, Yokoi N, Takahashi H, Kanagawa A, Kang CJ, Sargis RM, Seino S
- Organizer
  The 61st Annual Meeting of the Japan Diabetes Society
- Data Source
  KAKENHI-PROJECT-16F16418
[Presentation] Enhanced Gs- and Gq-signals in β-cells contributes to normalization of glucose tolerance and insulin secretion in β-cell specific Kir6.22018
- Author(s)
  Okechi S. Oduori, Kohtaro Minami, Norihide Yokoi, Harumi Takahashi, Takashi Miki, Yuko Maejima, Kenju Shimomura, Susumu Seino
- Organizer
  Keytsone symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02864
[Presentation] インスリン分泌を制御するシグナル伝達の分子機構に関する研究2018
- Author(s)
  清野　進
- Organizer
  第108回日本学士院賞授賞式
- Invited
- Data Source
  KAKENHI-PROJECT-18H02864
[Presentation] 肥満糖尿病モデルZFDMラットの膵島におけるタンパク質糖鎖修飾の病態生理学的意義2018
- Author(s)
  横井　伯英、速水　智英、波多野　直哉、日高　志保美、川畑　綾子、星野　貴一、星野　雅行、清野　進
- Organizer
  第65回日本実験動物会総会
- Data Source
  KAKENHI-PROJECT-18H02864
[Presentation] 膵β細胞のインクレチン応答性獲得におけるアミノ酸トランスポーターSNAT5の役割2018
- Author(s)
  マヒラ　アシム、横井伯英、グプルジャン　ゲニ、金川章子、星川律子、高橋晴美、清野進
- Organizer
  第61回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-18H02864
[Presentation] Chronic arsenic exposure impairs pancreatic beta cell function2017
- Author(s)
  Carmean CM, Kirkley AG, Yokoi N, Ritsuko H, Sugawara K, Sargis RM, Seino S
- Organizer
  Society of Environmental Toxicology and Chemistry Conference
- Place of Presentation
  Brussels, Belgium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] インクレチン応答性インスリン分泌増強機構の解明：インスリン顆粒内グルタミン酸の役割2017
- Author(s)
  グプルジャンゲニ、横井伯英、波多野直哉、韓桂栄、高橋晴美、清野進
- Organizer
  第60回日本糖尿病学会年次学術集会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] Beta-cell specific KATP Channel knockout mouse: diabetes, impaired insulin secretion and enhanced in cretin signalling2017
- Author(s)
  Oduori SO, Minami K, Takahashi H, Yokoi N, Herrera PL, Shimomura K, Seino S
- Organizer
  18th Servier-IGIS Symposium
- Place of Presentation
  St. Jean-Cap-Ferra, France
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] 膵β細胞間相互作用によるインクレチン応答性獲得に関与する分子の同定2017
- Author(s)
  マヒラアシム、横井伯英、星川律子、グプルジャンゲニ、高橋晴美、清野進
- Organizer
  第60回日本糖尿病学会年次学術集会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] Beta-cell glutamate signaling is critical for incretin-induced insulin secretion2017
- Author(s)
  Seino S
- Organizer
  KEYSTONE SYMPOSIA on Molecular and Cellular Biology
- Place of Presentation
  Copenhagen, Denmark
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] グルタミンによるインスリン分泌増強機構の解明2017
- Author(s)
  韓　桂栄、グプルジャンゲニ、横井伯英、村尾直哉、高橋晴美、清野　裕、清野　進
- Organizer
  第60回日本糖尿病学会年次学術集会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] Chronic Arsenic Exposure Impairs Pancreatic β-cell Function2017
- Author(s)
  Carmean CM, Kirkley AG, Yokoi N, Hoshikawa R, Sugawara K, Sargis RM, Seino S
- Organizer
  SETAC(The society of Environmental Toxicology and Chemistry Europe) 27th Annual Meeting
- Place of Presentation
  SQUARE Conference Center, Brussels, Belgium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16F16418
[Presentation] β細胞シグナリングからインスリン分泌促進薬を考える2017
- Author(s)
  清野　進
- Organizer
  第51回糖尿病学の進歩
- Place of Presentation
  京都
- Invited
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] Incretin and beta-cell metabolic signaling2017
- Author(s)
  横井伯英、村尾直哉、高橋晴美、清野　進
- Organizer
  第60回日本糖尿病学会年次学術集会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] Why are large islets unresponsive to incretins?2017
- Author(s)
  Seino S
- Organizer
  Joint Meeting of the EASD Islet Study Group & Beta Cell Workshop
- Place of Presentation
  Dresden, Germany
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] 肥満糖尿病におけるインクレチン応答性インスリン分泌障害機序の解明－ZFDMラット膵島を用いた検討－2017
- Author(s)
  速水智英、横井伯英、本田洸平、山口拓郎、グプルジャンゲニ、マヒラアシム、星川律子、清野　進
- Organizer
  第60回日本糖尿病学会年次学術集会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] Approaches to the development of novel small molecules that can be insulin secretagogues2017
- Author(s)
  高橋晴美、菅原健二、横井伯英、清野　進
- Organizer
  第60回日本糖尿病学会年次学術集会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] グルタミンによるインスリン分泌増強機構の解明2017
- Author(s)
  韓　桂栄、横井伯英、グプルジャンゲニ、村尾直哉、矢部大介、清野　裕、清野進
- Organizer
  第20回日本病態栄養学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] Chronic Arsenic Exposure Impairs Pancreatic β-cell Function2017
- Author(s)
  Carmean CM, Kirkley AG, Yokoi N, Hoshikawa R, Sugawara K, Sargis RM, Seino S
- Organizer
  The 9th Scientific Meeting of Asian Association for the Study of Diabetes
- Place of Presentation
  名古屋国際会議場(愛知県名古屋市）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16F16418
[Presentation] Impaired Insulin secretion and severe glucose intolerance caused by deleting b-cell specific KATP channels2017
- Author(s)
  Oduori SO, Minami K, Yokoi N, Takahashi H, Maejima Y, Shimomura K, Herrera PL, Seino S
- Organizer
  The 9th Scientific Meeting of Asian Association for the Study of Diabetes
- Place of Presentation
  Nagoya, Japan
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] メタボローム解析を用いたインクレチン応答性インスリン分泌障害の現認探索－ZFDMラット膵島を用いた検討－2017
- Author(s)
  本田洸平、横井伯英、山口拓郎、グプルジャンゲニ、速水智英、星川律子、清野進
- Organizer
  第31回日本糖尿病・肥満動物学会年次学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] Chronic arsenic exposure impairs pancreatic beta cell function2017
- Author(s)
  Carmean CM, Kirkley AG, Yokoi N, Hoshikawa R, Sugawara K, Sargis RM, Seino S
- Organizer
  The 9th Scientific Meeting of Asian Association for the Study of Diabetes
- Place of Presentation
  Nagoya, Japan
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] Don Steiner Memorial Lecture: Beta-cell signaling and insulin secretagogues - a path to improved treatment2017
- Author(s)
  Seino S
- Organizer
  18th Servier-IGIS Symposium
- Place of Presentation
  St. Jean-Cap-Ferra, France
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] 膵β細胞グルタミン酸シグナルのインスリン分泌における役割の解明 -CRISPR/Cas9による遺伝子改変膵β細胞株を用いた検討2017
- Author(s)
  村尾直哉、横井伯英、韓桂栄、グプルジャンゲニ、清野進
- Organizer
  第60回日本糖尿病学会年次学術集会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] Approaches to identification of novel small molecules that can be insulin secretagogues2017
- Author(s)
  Takahashi H, Sugawara K, Honda K, Yokoi N, Mori I, Nakaya H, Seino S
- Organizer
  Joint Meeting of the EASD Islet Study Group & Beta Cell Workshop
- Place of Presentation
  Dresden, Germany
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] Trans-S-1-propenyl-l-cysteine sulfoxide from Allium cepa, onions, has appreciable antidiabetic potential in streptozotocin-induced diabetic mice2016
- Author(s)
  Oduori SO, Sugawara K, Yoshida S, Takahashi H, Yokoi N Nakayama M, Seino S
- Organizer
  11th International Diabetes Federation Western Pacific Region Congress/8th Asian Association for the Study of Diabetes Scientific Meeting
- Place of Presentation
  Taipei, Taiwan
- Year and Date
  2016-10-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] プロテオミクスによるインスリン顆粒開口放出機構の解明2016
- Author(s)
  グプルジャンゲニ、横井伯英、波多野直哉、韓桂栄、清野進
- Organizer
  第59回日本糖尿病学会年次学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] Selective and sensitive quantification of glucagon and glucagon-related peptide hormones in human plasma using conventional LC/MS/MS2016
- Author(s)
  Yokoi N, Hoshikawa R, Matsubara T, Hirano I, Seino S
- Organizer
  The 64th ASMS Conference on Mass Spectrometry and Allied Topics
- Place of Presentation
  San Antonio, USA
- Year and Date
  2016-06-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] Mechanisms of insulin secretion -interplay among glucose, incretin, and sulfonylurea2016
- Author(s)
  Seino S
- Organizer
  DEBATE 2016 (Diabetes, Endocrinology, Basic Science, Advances in Technology & Education)
- Place of Presentation
  Bangalore, India
- Year and Date
  2016-01-29
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] レパグリニドとインクレチンによるインスリン分泌動態の解析2016
- Author(s)
  髙橋晴美、日高志保美、堰千紘、清野進
- Organizer
  第59回日本糖尿病学会年次学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] β-cell glutamate signaling in insulin secretion: the physiological and pathophysiological roles2016
- Author(s)
  Seino S
- Organizer
  11th International Diabetes Federation Western Pacific Region Congress/8th Asian Association for the Study of Diabetes Scientific Meeting
- Place of Presentation
  Taipei, Taiwan
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] 膵β細胞間相互作用によるインクレチン応答性獲得機構の解明　-偽膵島を用いた検討-2016
- Author(s)
  マヒラアシム、横井伯英、グプルジャンゲニ、星川律子、高橋晴美、清野進
- Organizer
  第59回日本糖尿病学会年次学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] CRISPR-Cas9システムを用いたグルタミン酸シグナル関連遺伝子欠損膵β細胞株の樹立とその解析2016
- Author(s)
  村尾直哉、横井伯英、韓　桂栄、グプルジャンゲニ、清野進
- Organizer
  第59回日本糖尿病学会年次学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] 膵β細胞の機能制御と細胞内代謝2016
- Author(s)
  清野　進, グプルジャンゲニ, 横井伯英
- Organizer
  第68回日本細胞生物学会大会
- Place of Presentation
  京都
- Invited
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] Antidiabetic effect of a sulfur compound, trans-S-1-propenyl-l-cysteine sulfoxide, in Allium cepa2016
- Author(s)
  Oduori SO, Sugawara K, Honda K, Takahashi H, Yokoi N, Nakayama M, Seino S
- Organizer
  第59回日本糖尿病学会年次学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] Impaired Incretin-induced Insulin Secretion in Enlarged Pancreatic Islets in a Novel Animal Model of Obese Type 2 Diabetes2016
- Author(s)
  Gheni G, Yokoi N, Yamaguchi T, Honda K, Hashim M, Tamura K, Seino S
- Organizer
  11th International Diabetes Federation Western Pacific Region Congress/8th Asian Association for the Study of Diabetes Scientific Meeting
- Place of Presentation
  Taipei, Taiwan
- Year and Date
  2016-10-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] KATPチャネルを標的とした新規低分子化合物の同定とその特性解析2016
- Author(s)
  菅原健二、本田洸平、霊園良恵、松本明郎、森一郎、中谷晴昭、清野進
- Organizer
  第59回日本糖尿病学会年次学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] New perspective in incretin-induced insulin secretion: The role of beta-cell glutamate signaling2016
- Author(s)
  Seino S
- Organizer
  3rd Annual Meeting of Daegyeong Diabetes Endocrine Society
- Place of Presentation
  Daegu, Korea
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] Simultaneous quantification of tryptophan-related metabolites as biomarkers for prediabetes2016
- Author(s)
  Yokoi N, Hoshikawa R, Matsubara T, Seino S
- Organizer
  The 64th ASMS Conference on Mass Spectrometry and Allied Topics
- Place of Presentation
  San Antonio, USA
- Year and Date
  2016-06-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] Cell signaling in insulin secretion and its clinical implications2016
- Author(s)
  Seino S
- Organizer
  17th International Congress of Endocrinology
- Place of Presentation
  Beijing, China
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] Cell signaling in insulin secretion: for better treatment of diabetes2016
- Author(s)
  Seino S
- Organizer
  Naomi Berrie Diabetes Conference, Columbia University
- Place of Presentation
  New York, USA
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] メタボロミクスによる糖尿病の病態解析2016
- Author(s)
  横井伯英、清野進
- Organizer
  第59回日本糖尿病学会年次学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] Second messengers in potentiating insuolin secretion2016
- Author(s)
  Seino S
- Organizer
  The 76th scientific sessions of the American Diabetes Association
- Place of Presentation
  New Orleans, USA
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] Roles of KATP channels in brain-islet axis2016
- Author(s)
  Seino S, Takahashi H
- Organizer
  21st EASD-Hagedorn Oxford Workshop
- Place of Presentation
  Oxford, UK
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] Mechanisms of the induction of incretin/cAMP responsiveness in insulin secretion: study by pseudoislets2016
- Author(s)
  Hashim M, Yokoi N, Gheni G, Hoshikawa R, Takahashi H, Seino S
- Organizer
  52nd Annual Meeting of the European Association for the Study of Diabetes
- Place of Presentation
  Munich, Germany
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] Glutamate is a critical cell signal in incretin-induced insulin secretion2016
- Author(s)
  Seino S
- Organizer
  DEBATE 2016 (Diabetes, Endocrinology, Basic Science, Advances in Technology & Education)
- Place of Presentation
  Bangalore, India
- Year and Date
  2016-01-30
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] 肥満糖尿病におけるインクレチン応答性インスリン分泌障害の原因探索－ZFDMラットを用いた検討－2016
- Author(s)
  本田洸平、横井伯英、山口拓郎、田村香楠子、グプルジャンゲニ、清野進
- Organizer
  第59回日本糖尿病学会年次学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] Chronic Arsenic Exposure Impairs Pancreatic Function2016
- Author(s)
  Carmean CM, Kirkley AG, Yokoi N, Hoshikawa R, Honda K, Gheni G, Sugawara K, Takahashi H, Sargis RM, Seino S
- Organizer
  17th Servier-IGIS Symposium
- Place of Presentation
  St. Jean-Cap-Ferra, France
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] Cell signaling in insulin secretion and its clinical implications2016
- Author(s)
  Seino S
- Organizer
  Ｔhe 20th Scientific Meeting of the Chinese Diabetes Society
- Place of Presentation
  Xiamen, China
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] Antidiabetic effect of a sulfur compound trans-S-1-propenyl-l-cysteine sulfoxide from Allium cepa2016
- Author(s)
  Oduori SO, Sugawara K, Takahashi H, Yokoi N, Nakayama M, Seino S
- Organizer
  The 76th scientific sessions of the American Diabetes Association
- Place of Presentation
  New Orleans, USA
- Year and Date
  2016-06-10
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] Evaluation of the pharmacokinetics of a novel anti-diabetic agent using conventional LC/MS/MS2016
- Author(s)
  Sugawara K, Yokoi N, Hoshikawa R, Matsubara T, Seino S
- Organizer
  The 64th ASMS Conference on Mass Spectrometry and Allied Topics
- Place of Presentation
  San Antonio, USA
- Year and Date
  2016-06-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] 新規肥満・糖尿病モデルZFDMラットにおける耐糖能障害の原因探索2016
- Author(s)
  本田洸平、横井伯英、山口拓郎、田村香楠子、グプルジャンゲニ、清野　進
- Organizer
  第30回日本糖尿病・肥満動物学会年次学術集会
- Place of Presentation
  埼玉
- Year and Date
  2016-03-12
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] Deletion of β-cell specific KATP channels causes severe glucose intolerance with impaired insulin secretion and enhanced incretin secretion2016
- Author(s)
  Oduori SO, Minami K, Yokoi N, Maejima Y, Takahashi H, Herrera PL, Shimomura K, Seino S
- Organizer
  52nd Annual Meeting of the European Association for the Study of Diabetes
- Place of Presentation
  Munich, Germany
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] インクレチンと血糖調節-膵β細胞の観点から2015
- Author(s)
  清野　進
- Organizer
  第58回日本糖尿病学会年次学術集会
- Place of Presentation
  下関
- Year and Date
  2015-05-22
- Invited
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] グルタミン酸シグナリングとβ細胞不全2015
- Author(s)
  横井伯英、グプルジャンゲニ、小倉雅仁、岩崎真宏、清野　進
- Organizer
  第58回日本糖尿病学会年次学術集会
- Place of Presentation
  下関
- Year and Date
  2015-05-22
- Invited
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] 新規2型糖尿病モデルZucker fatty diabetes mellitus（ZFDM）ラットにおける糖代謝関連表現型の経時的解析2015
- Author(s)
  山口拓郎、横井伯英、グプルジャンゲニ、別府正悠、日高志保美、星川律子、清野　進
- Organizer
  第58回日本糖尿病学会年次学術集会
- Place of Presentation
  下関
- Year and Date
  2015-05-23
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] 2型糖尿病モデルSDTラットにおけるトリプトファン代謝変動の解析2015
- Author(s)
  別府正悠、横井伯英、星川律子、日高志保美、松原稔哉、篠原雅巳、清野　進
- Organizer
  第29回日本糖尿病・肥満動物学会年次学術集会
- Place of Presentation
  京都
- Year and Date
  2015-02-14
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] メタボロミクスの糖尿病研究への応用2015
- Author(s)
  清野　進
- Organizer
  第88回日本内分泌学会学術総会
- Place of Presentation
  東京
- Year and Date
  2015-04-23
- Invited
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] インスリン分泌におけるグルタミン酸シグナルの役割2015
- Author(s)
  高橋晴美、グプルジャンゲニ、山口拓郎、横井伯英、清野　進
- Organizer
  第38回日本分子生物学会年会第88回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2015-12-03
- Invited
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] Mechanism of Induction of Incretin Responsiveness by Formation of Pseudoislets2015
- Author(s)
  Yokoi N, Hashim M, Gheni G, Hoshikawa R, Seino S
- Organizer
  The 7th Asian Association for the Study of Diabetes Scientific Meeting,
- Place of Presentation
  Hong Kong, China
- Year and Date
  2015-11-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] インスリン分泌の分子機構‐Up-to-date2015
- Author(s)
  清野　進
- Organizer
  第49回糖尿病学の進歩
- Place of Presentation
  岡山
- Year and Date
  2015-02-20
- Invited
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] SGLT2阻害薬：　副作用の観点から2015
- Author(s)
  矢部大介、清野　裕
- Organizer
  第30回日本糖尿病合併症学会
- Place of Presentation
  名古屋
- Year and Date
  2015-11-27
- Invited
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] 偽膵島形成によるインクレチン応答性獲得機構の検討2015
- Author(s)
  マヒラ　アシム、横井伯英、グプルジャン　ゲニ、星川律子、松原稔哉、岩崎真宏、柴崎忠雄、南幸太郎、清野　進
- Organizer
  第58回日本糖尿病学会年次学術集会
- Place of Presentation
  下関
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] インスリン分泌の分子機構‐グルコース代謝とcAMPシグナルの果たす重要な役割2015
- Author(s)
  清野　進
- Organizer
  第60回日本唾液腺学会学術集会
- Place of Presentation
  東京
- Year and Date
  2015-12-05
- Invited
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] インスリン分泌増強シグナルとしてのグルタミン酸の病態生理学的役割2015
- Author(s)
  グプルジャン　ゲニ、横井伯英、山口拓郎、村尾直哉、マイマイティリ　イマム、松原稔哉、星川律子、岩崎真宏、小倉雅仁、柴崎忠雄、南幸太郎、清野　進
- Organizer
  第58回日本糖尿病学会年次学術集会
- Place of Presentation
  下関
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] Incretin-based therapy for type 2 diabetes: Focus on East Asian perspectives and hypoglycemia2015
- Author(s)
  Yabe D, Seino Y
- Organizer
  The 7th Asian Association for the Study of Diabetes Scientific Meeting
- Place of Presentation
  Hong Kong, China
- Year and Date
  2015-11-21
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] 新規肥満・糖尿病モデルZFDMラットを用いたインスリン分泌研究2015
- Author(s)
  横井伯英、山口拓郎、艾尼吾甫尓江、清野　進
- Organizer
  第29回日本糖尿病・肥満動物学会年次学術集会
- Place of Presentation
  京都
- Year and Date
  2015-02-13
- Invited
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] Incretin, sulfonylurea, and glutamate2015
- Author(s)
  Seino S
- Organizer
  2015 International Conference on Diabetes and Metabolism (ICDM 2015), Korean Diabetes Association
- Place of Presentation
  Jeju, Korea
- Year and Date
  2015-10-17
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] 新規肥満・2型糖尿病モデルZFDMラットにおける糖尿病発症前の表現型解析2015
- Author(s)
  横井伯英、山口拓郎、グプルジャンゲニ、別府正悠、日高志保美、川畑綾子、星野貴一、星野雅行、清野　進
- Organizer
  第62回日本実験動物学会総会
- Place of Presentation
  京都
- Year and Date
  2015-05-30
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] Combinatorial effects of incretin and sufonylurea or glinide drugs on insulin secretion2015
- Author(s)
  Takahashi H, Shibasaki T, Hidaka S, Seino S
- Organizer
  Incretin 2015
- Place of Presentation
  Vancouver, Canada
- Year and Date
  2015-07-31
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] Glutamate as a critical cell signal for incretin-induced insulin secretion2015
- Author(s)
  Seino S
- Organizer
  Incretin 2015, a satellite symposium of International Federation of Diabetes (IDF) 2015
- Place of Presentation
  Vancouver, Canada
- Year and Date
  2015-07-31
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] Identification of a novel small molecule targeting KATP channels to stimulate insulin secretion2015
- Author(s)
  Sugawara K, Shibasaki T, Minami K, Matsumoto A, Seki C, Mori I, Nakaya H, Seino S
- Organizer
  16th International group on insulin secretion
- Place of Presentation
  Nice, France
- Year and Date
  2015-04-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] Pathophysiological role of β-cell glutamate signaling in insulin secretion2015
- Author(s)
  Gheni G, Yokoi N, Yamaguchi T, Murao N, Matsubara T, Hoshikawa, R, Iwasaki M, Ogura M, Shibasaki T, Minami K, Seino S
- Organizer
  The 2nd Japan-Korea Diabetes Forum
- Place of Presentation
  Shimonoseki, Japan
- Year and Date
  2015-05-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] インスリン分泌機構‐基礎研究から何が見えるか2015
- Author(s)
  清野　進
- Organizer
  第16回日本内分泌学会中国支部学術集会
- Place of Presentation
  広島
- Year and Date
  2015-08-29
- Invited
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] Preferential expression of liver specific genes and epigenetic memory of induced pluripotent stem cells derived from mouse exocrine pancreas2014
- Author(s)
  Minami K, Nukaya D, Hoshikawa R, Yokoi N, Seino S
- Organizer
  10th IDF-WPR Congress 2014 and 6th AASD Scientific Meeting
- Place of Presentation
  Suntec, Singapore
- Year and Date
  2014-11-21
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] インクレチンとスルホニル尿素薬の併用によるインスリン分泌増強作用におけるEpac2A/Rap1シグナルの役割2014
- Author(s)
  髙橋晴美、柴崎忠雄、髙橋利匡、日高志保美、小野愛夏、清野　進
- Organizer
  第57回日本糖尿病学会年次学術集会
- Place of Presentation
  大阪
- Year and Date
  2014-05-23
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] 薬物療法の新展開-基礎から臨床まで2014
- Author(s)
  清野　進
- Organizer
  第51回日本糖尿病学会近畿地方会
- Place of Presentation
  大阪
- Year and Date
  2014-10-25
- Invited
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] 自然発症モデルを用いた疾患バイオマーカーの探索－2型糖尿病モデルSDTラットを用いた検討－2014
- Author(s)
  横井伯英、別府正悠、星川律子、日高志保美、篠原雅巳、清野　進
- Organizer
  第61回日本実験動物学会総会
- Place of Presentation
  札幌
- Year and Date
  2014-05-16
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] Cell signaling in insulin secretion2014
- Author(s)
  Seino S
- Organizer
  The 68th Fujihara Seminar: Homeodynamics in clocks, sleep and metabolism
- Place of Presentation
  Izu, Japan
- Year and Date
  2014-09-25
- Invited
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] スルホニル尿素（SU）薬とcAMPの協調作用によるEpac2A活性化2014
- Author(s)
  柴崎忠雄、高橋利匡、高橋晴美、菅原健二、清野　進
- Organizer
  第57回日本糖尿病学会年次学術集会
- Place of Presentation
  大阪
- Year and Date
  2014-05-23
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] 膵β細胞の３次元培養によるインクレチン／cAMP反応性の誘導2014
- Author(s)
  柴崎忠雄、グプルジャンゲニ、マヒラアシム、岩崎真宏、星川律子、横井伯英、南幸太郎、清野　進
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2014-10-16
- Invited
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] Comparison of fish or meat intake before and after rice on postprandial glucose excursions and incretin secretion in type 2 diabetes: meal-sequence as a novel target in dietary therapy for diabetes2014
- Author(s)
  H. Kuwata, D. Yabe, M. Iwasaki, R. Usui, T. Kurose and Y. Seino
- Organizer
  10th IDF-WPR Congress 2014 and 6th AASD Scientific Meeting
- Place of Presentation
  Suntec, Singapore
- Year and Date
  2014-11-21
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] Comparison of fish or meat intake before and after rice on postprandial glucose excursions and incretin secretion in type 2 diabetes: Meal-sequence as a novel target in dietary therapies for diabetes2014
- Author(s)
  Yabe D, Kuwata H, Iwasaki M, Usui R, Kurose T, Seino Y
- Organizer
  The Endocrine Society 96th Annual Meeting
- Place of Presentation
  Chicago，USA
- Year and Date
  2014-06-21
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] Why are incretin-based therapies more efficient in East Asians2014
- Author(s)
  Iwasaki M, Yabe D, Kuwata H, Seino Y
- Organizer
  50th European Association for the Study of Diabetes Scientific Meeting, East West Forum
- Place of Presentation
  Vienna, Austria
- Year and Date
  2014-09-15
- Invited
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] マウス膵外分泌細胞からのiPS細胞の樹立と特性解析2014
- Author(s)
  南幸太郎、糠谷大樹、前田治代、星川律子、横井伯英、清野進
- Organizer
  第57回日本糖尿病学会年次学術集会
- Place of Presentation
  大阪
- Year and Date
  2014-05-22
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] 質量分析計を利用したプロテオミクス、メタボロミクスの糖尿病研究への応用2014
- Author(s)
  清野　進、松原稔哉、横井伯英
- Organizer
  第57回日本糖尿病学会年次学術集会
- Place of Presentation
  大阪
- Year and Date
  2014-05-23
- Invited
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] Effect of liraglutide on beta cell mass and function in alloxan diabetic mice2014
- Author(s)
  Tamura K, Minami K, Takahashi H, Kudo M, Seino S
- Organizer
  50th Annual Meeting of the European Association for the Study of Diabetes
- Place of Presentation
  Vienna, Austria
- Year and Date
  2014-09-18
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] Interplay between incretin and sulfonylurea through Epac2A/Rap1 signaling in insulin secretion2014
- Author(s)
  Takahashi H, Shibasaki T, Park J-H, Hidaka S, Takahashi T, Ono A, Song D-K, Seino S
- Organizer
  10th IDF-WPR Congress 2014 and 6th AASD Scientific Meeting
- Place of Presentation
  Suntec, Singapore
- Year and Date
  2014-11-21
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] インスリン分泌増強効果を有する新規低分子化合物の同定とその特性解析2014
- Author(s)
  下野琴絵、菅原健二、柴崎忠雄、清野　進
- Organizer
  第57回日本糖尿病学会年次学術集会
- Place of Presentation
  大阪
- Year and Date
  2014-05-24
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] 自然発症糖尿病モデルラットを用いた経時的メタボローム解析による2型糖尿病バイオマーカーの探索2014
- Author(s)
  別府正悠、横井伯英、星川律子、日高志保美、篠原雅巳、清野　進
- Organizer
  第57回日本糖尿病学会年次学術集会
- Place of Presentation
  大阪
- Year and Date
  2014-05-23
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] Identification of biomarkers for prediabetes: a study of rat models of type 2 diabetes2014
- Author(s)
  Yokoi N., Beppu, M., Hoshikawa, R., Hidaka, S., Matsubara, T., Shinohara, M., Seino, S
- Organizer
  10th IDF-WPR Congress 2014 and 6th AASD Scientific Meeting
- Place of Presentation
  Suntec, Singapore
- Year and Date
  2014-11-21
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] DPP-4阻害薬とSU薬の併用効果と重症低血糖：SU薬の種類による層別解析2014
- Author(s)
  岡村香織、矢部大介、久保田章、黒瀬　健、高橋晴美、高橋利匡、柴崎忠雄、清野　進、清野　裕
- Organizer
  第57回日本糖尿病学会年次学術集会
- Place of Presentation
  大阪
- Year and Date
  2014-05-23
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] 新規肥満性2型糖尿病モデルZucker fatty diabetes mellitus（ZFDM）ラットの病態解析2014
- Author(s)
  横井伯英、山口拓郎、吾甫尓江艾尼、日高志保美、別府正悠、星川律子、星野雅行、清野　進
- Organizer
  第57回日本糖尿病学会年次学術集会
- Place of Presentation
  大阪
- Year and Date
  2014-05-23
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] Mechanisms of insulin secretion2014
- Author(s)
  Seino S
- Organizer
  2nd DZD (The German Center of Diabetes Research)
- Place of Presentation
  Vienna, Austria
- Year and Date
  2014-09-15
- Invited
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] Effects of fish or meat intake before and after rice on postprandial glucose excursions and incretin secretion in type 2 diabetes: Meal-sequence as a novel target in dietary therapies for diabetes2014
- Author(s)
  Yabe D, Kuwata H, Iwasaki M, Usui R, Kurose T, Seino Y
- Organizer
  The American Diabetes Association 74th Scientific Sessions
- Place of Presentation
  San Francisco, USA
- Year and Date
  2014-06-13
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] 膵β細胞におけるグルタミン酸動態の代謝フラックス解析2014
- Author(s)
  吾甫尓江艾尼、横井伯英、星川律子、山口拓郎、岩崎真宏、小倉雅仁、南幸太郎、柴崎忠雄、清野　進
- Organizer
  第57回日本糖尿病学会年次学術集会
- Place of Presentation
  大阪
- Year and Date
  2014-05-24
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] cAMP, sulfonylureas and Epac22014
- Author(s)
  Seino S
- Organizer
  Islet Study Group Meeting 2014
- Place of Presentation
  Lausanne, Switzerland
- Year and Date
  2014-09-12
- Invited
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] 「食べる順番」が食後の血糖変動及びインクレチン分泌に与える影響：米飯喫食前の魚類摂取と肉類摂取の比較2014
- Author(s)
  桑田仁司、矢部大介、岩崎真宏、臼井亮太、渡邊好胤、表　孝徳、北谷直美、黒瀬　健、清野　裕
- Organizer
  第57回日本糖尿病学会年次学術集会
- Place of Presentation
  大阪
- Year and Date
  2014-05-24
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] Why are incretin-based therapies more efficient in East Asians2014
- Author(s)
  Yabe D, Kuwata H, Iwasaki M, Seino Y
- Organizer
  10th International Diabetes Federation Western Pacific Region Congress/6th Asian Association for the Study of Diabetes Scientific Meeting
- Place of Presentation
  Suntec, Singapore
- Year and Date
  2014-11-21
- Invited
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] アロキサン糖尿病マウスにおけるリラグルチドの膵β細胞に対する効果2014
- Author(s)
  田村香楠子、南幸太郎、高橋晴美、工藤麻耶、北野谷寿人、清野　進
- Organizer
  第57回日本糖尿病学会年次学術集会
- Place of Presentation
  大阪
- Year and Date
  2014-05-22
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] インスリン分泌の新たなメカニズム-インクレチンとSU薬の協調作用とその臨床的示唆2014
- Author(s)
  清野　進
- Organizer
  第52回日本糖尿病学会中国四国地方会
- Place of Presentation
  広島
- Year and Date
  2014-10-24
- Invited
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] 「食べる順番」が食後の血糖変動及びインクレチン分泌に与える影響：米飯喫食前の魚類摂取2014
- Author(s)
  岩崎真宏、矢部大介、桑田仁司、臼井亮太、渡邊好胤、表　孝徳、北谷直美、黒瀬　健、清野　裕
- Organizer
  第57回日本糖尿病学会年次学術集会
- Place of Presentation
  大阪
- Year and Date
  2014-05-23
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] GLP-1受容体作動薬2014
- Author(s)
  矢部大介、清野裕
- Organizer
  第57回日本糖尿病学会年次学術集会
- Place of Presentation
  大阪
- Year and Date
  2014-05-23
- Invited
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] 膵βシグナリングと糖尿病治療薬2012
- Author(s)
  清野進
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  京都(招待講演)
- Year and Date
  2012-03-14
- Data Source
  KAKENHI-PROJECT-21249057
[Presentation] Control of insulin granule exocytosis, FASEB Summer Research Conferences2011
- Author(s)
  Seino S
- Place of Presentation
  Colorado, USA
- Year and Date
  2011-08-14
- Data Source
  KAKENHI-PROJECT-21249057
[Presentation] 新たなインスリン分泌機構とその意義2011
- Author(s)
  清野進
- Organizer
  第84回日本内分泌学会学術総会
- Place of Presentation
  神戸(招待講演)
- Year and Date
  2011-04-21
- Data Source
  KAKENHI-PROJECT-21249057
[Presentation] Treating diabetes today : a matter of selectivity2011
- Author(s)
  Seino S
- Organizer
  Satellite Symposium of IDF World Diabetes Congress-Treatment of type 2 diabetes
- Place of Presentation
  Dubai, United Arab Emirates
- Year and Date
  2011-11-04
- Data Source
  KAKENHI-PROJECT-21249057
[Presentation] 膵β細胞のシグナリング:インクレチン/cAMPによるインスリン分泌増強メカニズム2011
- Author(s)
  清野進
- Organizer
  第84回日本生化学学会大会
- Place of Presentation
  京都(招待講演)
- Year and Date
  2011-09-21
- Data Source
  KAKENHI-PROJECT-21249057
[Presentation] Mechanisms of Insulin Secretion : Interplay of glucose Metabolism and cAMP Signaling and Sulfonylurea.2011
- Author(s)
  Seino S.
- Organizer
  Kick-off Workshop. Strategic Japanese-Danish Cooperative Program on Molecular Diabetology
- Place of Presentation
  神戸臨床研究情報センター(兵庫県)(招待講演)
- Year and Date
  2011-03-08
- Data Source
  KAKENHI-PROJECT-21249057
[Presentation] Control of insulin granule exocytosis2011
- Author(s)
  Seino S
- Organizer
  2011 International Conference of Diabetes and Metabolism
- Place of Presentation
  Seoul, Korea(招待講演)
- Data Source
  KAKENHI-PROJECT-21249057
[Presentation] Control of insulin granule exocytosis2011
- Author(s)
  Seino S
- Organizer
  Strategic Japanese-Denmark Cooperative Program on Molecular Diabetology
- Place of Presentation
  Copenhagen, Denmark(招待講演)
- Year and Date
  2011-10-21
- Data Source
  KAKENHI-PROJECT-21249057
[Presentation] Mechanisms of insulin secretion and type 2 diabetes2011
- Author(s)
  Seino S
- Organizer
  Programming beta-cell development. Impairment and regeneration
- Place of Presentation
  Helsingor, Denmark(招待講演)
- Year and Date
  2011-10-25
- Data Source
  KAKENHI-PROJECT-21249057
[Presentation] Control of insulin granule exocytosis, Danish-Japanese Workshop "Molecular Diabetology"2011
- Author(s)
  Seino S
- Place of Presentation
  Copenhagen, Denmark
- Year and Date
  2011-10-21
- Data Source
  KAKENHI-PROJECT-21249057
[Presentation] インスリン分泌研究の最前線2011
- Author(s)
  清野進
- Organizer
  第48回日本糖尿病学会近畿地方会
- Place of Presentation
  大阪(招待講演)
- Year and Date
  2011-10-29
- Data Source
  KAKENHI-PROJECT-21249057
[Presentation] インクレチンとスルホニル尿素薬のインタープレイ2011
- Author(s)
  清野進
- Organizer
  第54回日本糖尿病学会年次学術集会
- Place of Presentation
  札幌(招待講演)
- Year and Date
  2011-05-20
- Data Source
  KAKENHI-PROJECT-21249057
[Presentation] Mechanisms of insulin secretion and type 2 diabetes, Beta Cell Workshop 2011 : Programming Beta Cell Development2011
- Author(s)
  Seino S
- Organizer
  Impairment and Regeneration
- Place of Presentation
  Helsinger, Denmark
- Year and Date
  2011-10-25
- Data Source
  KAKENHI-PROJECT-21249057
[Presentation] Control of insulin granule exocytosis2011
- Author(s)
  Seino S
- Organizer
  FASEB Summer Research Conferences
- Place of Presentation
  Colorado, USA(招待講演)
- Data Source
  KAKENHI-PROJECT-21249057
[Presentation] Treating diabetes today : a matter of selectivity2011
- Author(s)
  Seino S
- Organizer
  Satellite Symposium of IDF World Diabetes Congress-Treatment of type 2 diabetes : a matter of proof
- Place of Presentation
  Dubai, United Arab Emirates(招待講演)
- Data Source
  KAKENHI-PROJECT-21249057
[Presentation] Mechanisms of insulin secretion : interplay of glucose metabolism, cAMP signaling, and sulfonylurea. Kick-off Workshop2011
- Author(s)
  Seino S
- Organizer
  Strategic Japanese-Danish Cooperative Program on Molecular Diabetology
- Place of Presentation
  Kobe, Japan
- Year and Date
  2011-03-08
- Data Source
  KAKENHI-PROJECT-21249057
[Presentation] The cell signaling in insulin secretion : a story of molecular targets of ATP, cAMP, and sulfonylurea.2010
- Author(s)
  Seino S.
- Organizer
  The 46th Annual Meeting of EASD, The 4th Albert Renold Lecture
- Place of Presentation
  Stockholm, (Sweden)(招待講演受賞講演)
- Year and Date
  2010-09-21
- Data Source
  KAKENHI-PROJECT-21249057
[Presentation] Novel aspects on the molecular regulation of insulin secretion2010
- Author(s)
  Seino S
- Organizer
  EASD islet study meeting 2010
- Place of Presentation
  Tallberg, Sweden
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-21249057
[Presentation] Cell signaling in insulin secretion.2010
- Author(s)
  Seino S.
- Organizer
  The 5th Annual Chicago Diabetes Day, The Donald F. Steiner Award for Outstanding Achievement in Diabetes Research
- Place of Presentation
  Chicago, (USA)(招待講演受賞講演)
- Year and Date
  2010-05-15
- Data Source
  KAKENHI-PROJECT-21249057
[Presentation] "Insulin Secretion" : SUR1 to Epac2.2010
- Author(s)
  Seino S.
- Organizer
  70th Scientific Sessions, American Diabetes Association
- Place of Presentation
  Orlando, (USA)(招待講演)
- Year and Date
  2010-06-29
- Data Source
  KAKENHI-PROJECT-21249057
[Presentation] The cell signaling in insulin secretion : a story of molecular targets of ATP, cAMP, and sulfonylurea2010
- Author(s)
  Seino S
- Organizer
  The 46th Annual Meeting of EASD, The 4th Albert Renold Lecture
- Place of Presentation
  Stockholm, Sweden
- Year and Date
  2010-09-21
- Data Source
  KAKENHI-PROJECT-21249057
[Presentation] Cell signaling in insulin secretion. The 5th Annual Chicago Diabetes Day2010
- Author(s)
  Seino S
- Organizer
  The University of Chicago Diabetes Research and Training Center
- Place of Presentation
  Chicago, USA
- Year and Date
  2010-05-15
- Data Source
  KAKENHI-PROJECT-21249057
[Presentation] Novel aspects on the molecular regulation of insulin secretion.2010
- Author(s)
  Seino S.
- Organizer
  EASD islet study meeting 2010(ISG2010)
- Place of Presentation
  Tallberg, (Sweden)(招待講演)
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-21249057
[Presentation] The cell signaling in insulin secretion : Epac2-mediated mechanisms.2010
- Author(s)
  Seino S.
- Organizer
  The 8th International Diabetes Federation Western Pacific Region Congress
- Place of Presentation
  Busan, (Korea)(招待講演)
- Data Source
  KAKENHI-PROJECT-21249057
[Presentation] Role of Epac2 in insulin secretion2010
- Author(s)
  Seino S
- Organizer
  Danish-Japanese Workshop on Molecular Diabetology
- Place of Presentation
  Copenhagen, Denmark
- Year and Date
  2010-03-23
- Data Source
  KAKENHI-PROJECT-21249057
[Presentation] Symposium on "Insulin Secretion": SUR1 to Epac22010
- Author(s)
  Seino S
- Organizer
  70th Scientific Sessions, American Diabetes Association
- Place of Presentation
  Orlando, USA
- Year and Date
  2010-06-29
- Data Source
  KAKENHI-PROJECT-21249057
[Presentation] Molecular Mechanism on Insulin Secretion2009
- Author(s)
  清野進
- Organizer
  The 25th Kumamoto Medical Bioscience & Global COE Cell Fate Regulation Research and Education Unit Joint Symposium
- Place of Presentation
  ANAホテル熊本ニュースカイ(熊本県)
- Year and Date
  2009-11-13
- Data Source
  KAKENHI-PROJECT-21249057
[Presentation] Recent Advanced in Beta Cell Biology : Scientific and Clinical Implications2009
- Author(s)
  清野進
- Organizer
  Signal transduction in the islet beta cell(hosted by the Banting and Best Diabetes Center, University of Toronto)
- Place of Presentation
  Toronto, Canada
- Year and Date
  2009-10-16
- Data Source
  KAKENHI-PROJECT-21249057
[Presentation] New approaches toward understanding mechanisms of insulin secretion2009
- Author(s)
  Seino S
- Organizer
  The 36th International Congress of Physiological Sciences
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2009-07-28
- Data Source
  KAKENHI-PROJECT-21249057
[Presentation] Diabetes, Research and Training Center(DRTC) Seminar : Pancreatic b-cell signaling : for better understanding and treatment of diabetes2009
- Author(s)
  Seino S
- Organizer
  Washington University School of Medicine
- Place of Presentation
  St Louis, USA
- Year and Date
  2009-10-13
- Data Source
  KAKENHI-PROJECT-21249057
[Presentation] New approaches toward understanding mechanisms of insulin secretion2009
- Author(s)
  清野進
- Organizer
  The 36th International Congress of Physiological Sciences
- Place of Presentation
  国立京都国際会館(京都府)
- Year and Date
  2009-07-28
- Data Source
  KAKENHI-PROJECT-21249057
[Presentation] インクレチンとインスリン分泌2009
- Author(s)
  清野進
- Organizer
  第82回日本内分泌学会学術総会
- Place of Presentation
  群馬県民会館(群馬県)
- Year and Date
  2009-04-23
- Data Source
  KAKENHI-PROJECT-21249057
[Presentation] Recent Advanced in Beta Cell Biology : Scientific and Clinical Implications(hosted by the Banting and Best Diabetes Center, University of Toronto)2009
- Author(s)
  Seino S
- Organizer
  Signal transduction in the islet beta cell
- Place of Presentation
  Toronto, Canada
- Year and Date
  2009-10-16
- Data Source
  KAKENHI-PROJECT-21249057
[Presentation] Pancreatic beta cell signaling : for better understanding and treatment of diabetes, Plenary Lecture2009
- Author(s)
  Seino S
- Organizer
  15th Korea-Japan Symposium on Diabetes Mellitus
- Place of Presentation
  Jeju, Korea
- Year and Date
  2009-11-21
- Data Source
  KAKENHI-PROJECT-21249057
[Presentation] Diabetes, Research and Training Center(DRTC)Seminar : Pancreatic β-cell signaling : for better understanding and treatment of diabetes2009
- Author(s)
  清野進
- Organizer
  Washington University School of Medicine
- Place of Presentation
  St.Louis, USA.
- Year and Date
  2009-10-13
- Data Source
  KAKENHI-PROJECT-21249057
[Presentation] cAMP niyoru insulin bunpitsu no seigyo.2008
- Author(s)
  Shibasaki T, Seino S
- Organizer
  Advances in Diabetology 42nd Annual Post Graduate Course
- Place of Presentation
  Takamatsu
- Year and Date
  2008-02-15
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Presentation] Regulation of insulin granule dynamics2007
- Author(s)
  Seino, S
- Organizer
  14th Japan-Korea Symposium on Diabetes Mellit us-
- Place of Presentation
  京都
- Year and Date
  2007-10-05
- Data Source
  KAKENHI-PROJECT-15002002
[Presentation] Regulation of insulin granule dynamics.2007
- Author(s)
  Seino S
- Organizer
  The 14th Japan-Korea Symposium on Diabetes Mellitus -Diabetes and Metabolic Syndrome in Asia
- Place of Presentation
  京都
- Year and Date
  2007-10-05
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Presentation] Regulation of insulin granule dynamics.2007
- Author(s)
  Seino S
- Organizer
  14th Japan-Korea Symposium on Diabetes Mellitus -Diabetes and Metabolic Syndrome in Asia-.
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2007-10-05
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Presentation] Regulation of insulin granule exocytosis by cAMP.2007
- Author(s)
  Seino S
- Organizer
  The European Association for the Study of Diabetes (EASD) Islet Study Group Symposium 2007.
- Place of Presentation
  Brussels, Belgium
- Year and Date
  2007-09-22
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Presentation] Regulation of insulin granule dynamics.2007
- Author(s)
  Seino S
- Organizer
  The 33rd Autumn Congress of Korean Diabetes Association.
- Place of Presentation
  Busan, Korea
- Year and Date
  2007-11-09
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Presentation] Regulation of insulin granule exocytosis by cAMP2007
- Author(s)
  Seino, S
- Organizer
  EASD Islet Study Group Symposium 2007
- Place of Presentation
  Brussels(Bclgium)
- Year and Date
  2007-09-22
- Data Source
  KAKENHI-PROJECT-15002002
[Presentation] Regulation of insulin granule dynamics2007
- Author(s)
  Seino, S
- Organizer
  The 33rd Autumn Congress of Korean Diabetes Association
- Place of Presentation
  Busan(Korea)
- Year and Date
  2007-11-09
- Data Source
  KAKENHI-PROJECT-15002002
[Presentation] Regulation of insulin granule exocytosis by cAMP.2007
- Author(s)
  Seino S
- Organizer
  The European Association for the Study of Diabetes (EASD) Islet Study Group Symposium 2007
- Place of Presentation
  Brussels, Belgium
- Year and Date
  2007-09-22
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Presentation] Regulation of insulin granule dynamics.2007
- Author(s)
  Seino S
- Organizer
  The 33rd Autumn Congress of Korean Diabetes Association
- Place of Presentation
  Busan, Korea
- Year and Date
  2007-11-09
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Presentation] Regulation of insulin granule exocytosis by cAMP.2007
- Author(s)
  Shibasaki T, Takahashi H, Seino S
- Organizer
  The 50th Annual Meeting of the Japan Diabetes Society
- Place of Presentation
  Sendai
- Year and Date
  2007-05-25
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Presentation] Integration of intracellular signals in insulin granule exocytosis2006
- Author(s)
  Seino S
- Organizer
  Nobel Minisymposium : Frontiers in Calcium Channel Research from Basics to Diseases
- Place of Presentation
  Stockholm, Sweden
- Year and Date
  2006-05-05
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Presentation] 膵β細胞の研究の進歩と展望2006
- Author(s)
  清野進
- Organizer
  第49回日本糖尿病学会年次学術集会
- Place of Presentation
  東京
- Year and Date
  2006-05-25
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Presentation] 膵β細胞の機能と再生2006
- Author(s)
  清野進
- Organizer
  第79回日本内分泌学会学術総会
- Place of Presentation
  神戸
- Year and Date
  2006-05-20
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Presentation] Role of cAMP signaling in insulin granule exocytosis2006
- Author(s)
  Seino S
- Organizer
  The 6th Congress of the Federation of Asian and Oceanian Physiological Societies
- Place of Presentation
  Seoul, Korea
- Year and Date
  2006-10-17
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Presentation] Role of cAMP signaling in insulin granule exocytosis.2006
- Author(s)
  Seino S
- Organizer
  The 6th Congress of the Federation of Asian and Oceanian Physiological Societies.
- Place of Presentation
  Seoul, Korea
- Year and Date
  2006-10-17
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Presentation] 膵β細胞障害の分子機構2006
- Author(s)
  清野進
- Organizer
  第41回糖尿病学の進歩
- Place of Presentation
  札幌
- Year and Date
  2006-09-29
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Presentation] Integration of intracellular signals in insulin granule exocytosis.2006
- Author(s)
  Seino S
- Organizer
  Nobel Minisymposium : Frontiers in Calcium Channel Research from Basics to Diseases.
- Place of Presentation
  Stockholm, Sweden
- Year and Date
  2006-05-05
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Presentation] Regeneration of pancreatic β-cells : in vitro and in vivo models.2006
- Author(s)
  Seino S
- Organizer
  The 10th Chinese Diabetes Society Scientific Congress.
- Place of Presentation
  Guangzhou, China.
- Year and Date
  2006-10-09
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Presentation] Sui β-saibou no kinou to saisei.2006
- Author(s)
  Seino S
- Organizer
  The 79th Japan Endocrine Society Meeting
- Place of Presentation
  Kobe
- Year and Date
  2006-05-20
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Presentation] Regeneration of pancreatic β-cells : in vitro and in vivo models2006
- Author(s)
  Seino S
- Organizer
  The 10th Chinese Diabetes Society Scientific Congress
- Place of Presentation
  Guangzhou, China
- Year and Date
  2006-10-09
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Presentation] Sui β-saibou no kenkyuu no shinpo to tenbou.2006
- Author(s)
  Seino S
- Organizer
  The 47th Annual Meeting of the Japan Diabetes Society
- Place of Presentation
  Tokyo
- Year and Date
  2006-05-25
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Presentation] Sui β-saibou no shintenkai.2005
- Author(s)
  Seino S
- Organizer
  The 71st Annual Meeting of the Japan Diabetes Society, Chubu Branch
- Place of Presentation
  Gifu
- Year and Date
  2005-03-26
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Presentation] Sui β-saibou kenkyu to tounyoubyou2005
- Author(s)
  Seino S
- Organizer
  The 11th Annual Meeting of the Japanese Society of Ophthalmic Diabetology
- Place of Presentation
  Nagoya
- Year and Date
  2005-03-05
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Presentation] Beta cell signaling2005
- Author(s)
  Seino S
- Organizer
  The Donald F. Steiner Symposium
- Place of Presentation
  Chicago, USA
- Year and Date
  2005-07-15
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Presentation] Tounyoubyou ni taisuru saisei iryou no tenbou2005
- Author(s)
  Seino S
- Organizer
  The 48th Annual Meeting of the Japan Diabetes Association
- Place of Presentation
  Kobe
- Year and Date
  2005-05-14
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Presentation] 膵β細胞研究の新展開2005
- Author(s)
  清野進
- Organizer
  第71回日本糖尿病学会中部地方会
- Place of Presentation
  岐阜
- Year and Date
  2005-03-26
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Presentation] Sui β-saibou no seibutsugaku2005
- Author(s)
  Seino S
- Organizer
  The 17th Takato Molecular Cellular Biology Symposium
- Place of Presentation
  Nagano
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Presentation] 膵β細胞の生物学2005
- Author(s)
  清野進
- Organizer
  第17回高遠・分子細胞生物学シンポジウム
- Place of Presentation
  長野
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Presentation] Molecular mechanism of cAMP-regulated insulin granule exocytosis.2005
- Author(s)
  Shibasaki T, Seino S
- Organizer
  The 82nd Annual Meeting of Physiological Society of Japan
- Place of Presentation
  Sendai
- Year and Date
  2005-05-20
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Presentation] The integration of intracellular signals in regulated exocytosis : the pancreatic β-cell model2005
- Author(s)
  清野進
- Organizer
  第58回日本細胞生物学会大会
- Place of Presentation
  大宮
- Year and Date
  2005-06-15
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Presentation] 膵β細胞研究と糖尿病.2005
- Author(s)
  清野進
- Organizer
  第11回日本糖尿病眼学会総会
- Place of Presentation
  名古屋
- Year and Date
  2005-03-05
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Presentation] Beta cell signaling.2005
- Author(s)
  Seino S
- Organizer
  The Donald F Steiner Symposium.
- Place of Presentation
  Chicago, USA
- Year and Date
  2005-07-15
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Presentation] 糖尿病に対する再生医療の展望2005
- Author(s)
  清野進
- Organizer
  第48回日本糖尿病協会総会及び年次集会
- Place of Presentation
  神戸
- Year and Date
  2005-05-14
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Presentation] Molecular Mechanism of cAMP-regulated Insulin Granule Exocytosis2005
- Author(s)
  Shibasaki T, Seino S
- Organizer
  第82回日本生理学会大会
- Place of Presentation
  仙台
- Year and Date
  2005-05-19
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Presentation] Tounyoubyou model doubutsu niyoru sui β-saibou kinou kaiseki2005
- Author(s)
  Seino S
- Organizer
  The 19th Japan Association of Animal Diabetes Research
- Place of Presentation
  Kyoto
- Year and Date
  2005-02-04
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Presentation] The integration of intracellular signals in regulated exocytosis : the pancreatic β-cell model.2005
- Author(s)
  Seino S
- Organizer
  The 58th Annual Meeting of the Japan Society for Cell Biology
- Place of Presentation
  Omiya
- Year and Date
  2005-06-15
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Presentation] 糖尿病モデル動物による膵β細胞機能解析.2005
- Author(s)
  清野進
- Organizer
  第19回日本糖尿病動物研究会年次学術集会
- Place of Presentation
  京都
- Year and Date
  2005-02-04
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Presentation] Insulin bunpitsu no kouzou.2004
- Author(s)
  Seino S
- Organizer
  The 47th Annual Meeting of the Japan Diabetes Society
- Place of Presentation
  Yokohama
- Year and Date
  2004-05-14
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Presentation] Integration of intracellular signals in insulin granule exocytosis.2004
- Author(s)
  Seino S
- Organizer
  Diabetes Endocrinology Research Center, University of Washington, Special Symposium : Cellular Aspects of Insulin Secretion and Insulin Action
- Place of Presentation
  Seattle, USA
- Year and Date
  2004-09-14
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Presentation] The biology of K_<ATP> channels : Emphasis on Kir.2004
- Author(s)
  Seino S
- Organizer
  The 5th Servier-IGIS Symposium.
- Place of Presentation
  St. Jean-Cap-Ferrat, France.
- Year and Date
  2004-03-18
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Presentation] Integration of stimulus-secretion coupling in insulin granule exocytosis.2004
- Author(s)
  Seino S
- Organizer
  Second Korea-Japan Joint Symposium : Endocrine and Exocrine Secretion.
- Place of Presentation
  Sapporo, Japan
- Year and Date
  2004-06-04
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Presentation] Sui β-saibou no seibutsugaku - insulin bunpitsu system no keisei kikou.2004
- Author(s)
  Seino S
- Organizer
  Adipomics, Open symposium, Grant-in-Aid for Scientific Research on Priority Areas from the Ministry of Education, Culture, Sports, Science, and Technology
- Place of Presentation
  Osaka
- Year and Date
  2004-10-01
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Presentation] Integration of ATP, cAMP and Calcium Signaling in Insulin Secretion2004
- Author(s)
  Seino S
- Organizer
  International Symposium on Pathogenesis of Diabetes Mellitus
- Place of Presentation
  神戸
- Year and Date
  2004-01-08
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Presentation] 膵β細胞の生物学 - インスリン分泌システムの形成機構2004
- Author(s)
  清野進
- Organizer
  文部科学省特定領域研究-アディポミクス、脂肪細胞の機能世界と破綻病態の解明公開シンポジウム
- Place of Presentation
  大阪
- Year and Date
  2004-10-01
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Presentation] Integration of stimulus-secretion coupling in insulin granule exocytosis2004
- Author(s)
  清野進
- Organizer
  第81回日本生理学会大会 Second Korea-Japan Joint Symposium : Endocrine and Exocrine Secretion
- Place of Presentation
  札幌
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Presentation] Evolution of Type II Diabetes and Obesity Marketplace to the year 20202004
- Author(s)
  清野進
- Organizer
  Key Opinion Leader Advisory Board
- Place of Presentation
  東京
- Year and Date
  2004-02-02
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Presentation] Insulin bunpitsu system no keisei to sono hatan2004
- Author(s)
  Seino S
- Organizer
  The 22nd JES Summer Seminar on Endocrinology and Metabolism
- Place of Presentation
  Awaji
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Presentation] インスリン分泌システムの形成とその破綻2004
- Author(s)
  清野進
- Organizer
  第22回内分泌・代謝学サマーセミナー
- Place of Presentation
  淡路
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Presentation] Integration of intracellular signals in insulin granule exocytosis2004
- Author(s)
  Seino S
- Organizer
  Diabetes Endocrinology Research Center, University of Washington, Special Symposium : Cellular Aspects of Insulin Secretion and Insulin Action
- Place of Presentation
  Seattle, USA
- Year and Date
  2004-09-14
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Presentation] Integration of stimulus-secretion coupling in insulin granule exocytosis.2004
- Author(s)
  Seino S
- Organizer
  The 81st Annual Meeting of the Physiological Society of Japan, Second Korea-Japan Joint Symposium : Endocrine and Exocrine Secretion
- Place of Presentation
  Sapporo
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Presentation] インスリン分泌の分子構造2004
- Author(s)
  清野進
- Organizer
  第47回日本糖尿病学会年次学術集会
- Place of Presentation
  東京
- Year and Date
  2004-05-14
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Presentation] Mechahisms of insulin secretion2004
- Author(s)
  Seino S
- Organizer
  Pioneers in Physiological Research and Challenges for 21^<st>Century Physiologists, Special Symposium
- Place of Presentation
  Seoul, Korea
- Year and Date
  2004-10-28
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Presentation] ATP-sensitive (K_<ATP>) channel as the molecular target of sulfonylurea : its physiology and pathophysiology.2004
- Author(s)
  Seino S
- Organizer
  The Research Symposium of Korean Diabetes Association, Special Seminar
- Place of Presentation
  Seoul, Korea
- Year and Date
  2004-10-27
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Presentation] The biology of K_<ATP> channels : Emphasis on Kir2004
- Author(s)
  Seino S
- Organizer
  The 5th International group on insulin secretion Symposium
- Place of Presentation
  St. Jean-Cap-Ferrat, France
- Year and Date
  2004-03-18
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Presentation] Integration of stimulus-secretion coupling in insulin granule exocytosis2004
- Author(s)
  Seino S
- Organizer
  The 81st Annual Meeting of the Physiological Society of Japan, Second Korea-Japan Joint Symposium : Endocrine and Exocrine Secretion
- Place of Presentation
  札幌
- Year and Date
  2004-06-04
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Presentation] Mechanisms of insulin secretion.2004
- Author(s)
  Seino S
- Organizer
  Pioneers in Physiological Research and Challenges for 21st Century Physiologists, Special Symposium.
- Place of Presentation
  Seoul, Korea
- Year and Date
  2004-10-27
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Presentation] Integration of ATP, cAMP and calcium signaling in insulin secretion.2004
- Author(s)
  Seino S
- Organizer
  International Symposium on Pathogenesis of Diabetes Mellitus.
- Place of Presentation
  Kobe, Japan
- Year and Date
  2004-01-08
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Presentation] Evolution of Type II Diabetes and Obesity Marketplace to the year 2020.2004
- Author(s)
  Seino S
- Organizer
  Key Opinion Leader Advisory Board.
- Place of Presentation
  Tokyo
- Year and Date
  2004-02-02
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Presentation] ATP-sensitive (K_<ATP>)channel as the molecular target of sulfonylurea : its physiology and pathophysiologv2004
- Author(s)
  Seino S
- Organizer
  The Research Symposium of Korean Diabetes Association, special Seminar
- Place of Presentation
  Seoul, Korea
- Year and Date
  2004-10-27
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Presentation] Classical and novel effectors2003
- Author(s)
  Seino S
- Organizer
  The18th International Diabetes Federation Congress, Symposium : Normal β-cell stimulus-secretion coupling
- Place of Presentation
  Paris, France
- Year and Date
  2003-08-26
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Presentation] Positional cloning of the autoimmune type 1 diabetes gene in the KDP rat2003
- Author(s)
  Yokoi N, Seino S
- Organizer
  Cold Spring Harbor Laboratory Winter Biotechnology Conference on Rat Genomics and Models
- Place of Presentation
  Cold spring Harbor, USA
- Year and Date
  2003-12-12
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Presentation] SU zai no hyouteki bunshi K_<ATP> channel -atarashii tenkai-.2003
- Author(s)
  Seino S
- Organizer
  The 46th Annual Meeting of the Japan Diabetes Society
- Place of Presentation
  Toyama
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Presentation] SU剤の標的分子K_<ATP>チャネル-新しい展開-2003
- Author(s)
  清野進
- Organizer
  第46回日本糖尿病学会年次学術集会
- Place of Presentation
  富山
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Presentation] Involvement of Piccolo/cAMP-GEFII/Rim2. Complex in cAMP-dependent Insulin Secretion.2003
- Author(s)
  Shibasaki T, Fujimoto K, Yokoi N, Seino S
- Organizer
  The 76th Annual Meeting of Japanese Biochemical Society
- Place of Presentation
  Yokohama
- Year and Date
  2003-10-16
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Presentation] Ichigata tounyoubyou model KDP rat ni okeru kanjyusei idenshi no positional cloning.2003
- Author(s)
  Yokoi N, Seino S
- Organizer
  The 46th Annual Meeting of the Japan Diabetes Society
- Place of Presentation
  Toyama
- Year and Date
  2003-05-23
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Presentation] Classical and novel effectors.2003
- Author(s)
  Seino S
- Organizer
  The 18th International Diabetes Federation Congress, Symposium : Normal β-cell stimulus-secretion coupling.
- Place of Presentation
  Paris, France
- Year and Date
  2003-08-26
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Presentation] Positional cloning of the autoimmune type 1 diabetes gene in the KDP rat.2003
- Author(s)
  Yokoi N, Seino S
- Organizer
  Cold Spring Harbor Laboratory Winter Biotechnology Conference on Rat Genomics and Models.
- Place of Presentation
  Cold Spring Harbor, USA
- Year and Date
  2003-12-12
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Presentation] cAMP signaling in insulin secretion: Role of Epac2.
- Author(s)
  Seino S
- Organizer
  VX Servier-IGIS Symposium
- Place of Presentation
  Saint-Jean-Cap-Ferrat, France
- Invited
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] Elucidation of pancreatic beta-cell fate after birthusing Ins2-CreER/R26R-YFP double knock-in mouse.
- Author(s)
  Tamura K, Minami K, Iemoto K, Nakamura K, Seino S
- Organizer
  9th International Diabetes Feferation Western Pacific Region Congress/4th Scientific Meeting of the Asian Association for the Study of Diabetes
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] PGRN: a novel therapeutic target and biomarker for insulin resistance and obesity identified by differential proteome analysis.
- Author(s)
  Matsubara T, Minami K, Yokoi N, Nishimura O, Seino S
- Organizer
  19th International Mass Spectrometry Conference
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] Interaction of incretin and sulfonylurea through Epac2 in insulin secretion.
- Author(s)
  Takahashi H, Shibasaki T, Hidaka S, Takahashi T, Ono A, Susumu Seino S
- Organizer
  Beta Cell Workshop 2013 Kyoto
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] インスリン分泌のメカニズム
- Author(s)
  清野　進
- Organizer
  第48回糖尿病学の進歩
- Place of Presentation
  札幌
- Invited
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] Identification and characterization of the binding site and properties of antidiabetic sulfonylurea drugs in the cAMP sensor Epac2A.
- Author(s)
  Takahashi T, Shibasaki T, Takahashi H, Sugawara K, Ono A, Seino S
- Organizer
  Beta Cell Workshop 2013 Kyoto
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] Beta-cell signaling in insulin secretion: metabolomics approach.
- Author(s)
  Seino S
- Organizer
  2013 Seoul International Congress of Endocrinology and Metabolism
- Place of Presentation
  Seoul, Korea
- Invited
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] The malate-aspartate shuttle is essential for incretin-induced insulin secretion.
- Author(s)
  Seino S
- Organizer
  Beta-cell Workshop 2013 Kyoto
- Place of Presentation
  Kyoto, Japan
- Invited
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] Interaction of incretin and sulfonylurea through Epac2A signaling in insulin secretion.
- Author(s)
  Takahashi H, Shibasaki T, Hidaka S, Ono A, Takahashi T, Seino S
- Organizer
  49th Annual Meeting of the European Association for the Study of Diabetes
- Place of Presentation
  Barcelona, Spain
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] Role of cellular glutamate in incretin-induced insulin secretion.
- Author(s)
  Yokoi N., Gheni G, Ogura M, Iwasaki M, Minami K, Shibasaki T, Seino S
- Organizer
  VX Servier-IGIS Symposium
- Place of Presentation
  Saint-Jean-Cap-Ferrat, France
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] Expression of gastrin in pancreatic islets of a mouse model of beta cell regeneration.
- Author(s)
  Minami K, Kitanoya H, Tamura K, Kudo M, Takahashi H, Seino S
- Organizer
  9th International Diabetes Feferation Western Pacific Region Congress/4th Scientific Meeting of the Asian Association for the Study of Diabetes
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] Evaluation of the effect of liraglutide on beta cell fate in alloxan diabetic mice by tamoxifen-inducible Cre/loxP system.
- Author(s)
  Tamura K, Minami K, Takahashi H, Kudo M, Kitanoya H, Seino S
- Organizer
  49th Annual Meeting of the European Association for the Study of Diabetes
- Place of Presentation
  Barcelona, Spain
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] 新規肥満・糖尿病モデルZucker fatty diabetes mellitus（ZFDM）ラットの確立
- Author(s)
  横井伯英、星野雅行、日高志保美、別府正悠、星川律子、清野　進
- Organizer
  第27回日本糖尿病・肥満動物学会年次学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] Clarification of molecular mechanism underlying Epac2A activation by antidiabetic sulfonylurea drugs
- Author(s)
  Shibasaki T, Takahashi T, Takahashi H, Sugawara K, Seino S
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] The role of malate-aspartate shuttle-derived glutamate in incretin-potentiated insulin secretion.
- Author(s)
  Ogura M, Iwasaki M, Gheni G, Minami K, Yokoi N, Shibasaki T, Seino S
- Organizer
  第56回日本糖尿病学会年次学術集会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] Application of metabolomics of pancreatic beta-cell biology.
- Author(s)
  Seino S
- Organizer
  The 3rd GCOE International Symposium on Signal Transduction Medicine in the Coming Generation
- Place of Presentation
  Kobe, Japan
- Invited
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] 経時的メタボローム解析による2型糖尿病バイオマーカーの探索－非肥満性2型糖尿病モデルSDTラットを用いた検討－
- Author(s)
  横井伯英、別府正悠、星川律子、日高志保美、篠原雅巳、清野　進
- Organizer
  第28回日本糖尿病・肥満動物学会年次学術集会
- Place of Presentation
  宮崎
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] Search for biomarkers of type 2 diabetes by metabolome analysis.
- Author(s)
  Yokoi N, Yoshida E, Hoshikawa R, Hidaka S, Beppu M, Oya M, Seino S
- Organizer
  9th International Diabetes Feferation Western Pacific Region Congress/4th Scientific Meeting of the Asian Association for the Study of Diabetes
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] Critical role of malate-aspartate shuttle in induction of incretin responsiveness by formation of pseudoislets.
- Author(s)
  Ghupurjan G, Iwasaki M, Ogura M, Yokoi N, Shibasaki T, Minami K, Seino S
- Organizer
  9th International Diabetes Feferation Western Pacific Region Congress/4th Scientific Meeting of the Asian Association for the Study of Diabetes
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] Role of actin dynamics regulated by N-WASP and cofilin in insulin secretion in pancreatic beta-cells.
- Author(s)
  Shibasaki T, Uenishi1 E, Takahashi H, Hamaguchi1 H, Seino S
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] アロキサン誘導糖尿病マウスの膵β細胞に対するリラグルチドの効果
- Author(s)
  工藤麻耶、南幸太郎、田村香楠子、北野谷寿人、家本啓佑、高橋晴美、清野進
- Organizer
  第56回日本糖尿病学会年次学術集会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] Mechanisms of insulin secretion: role of Epac 2.
- Author(s)
  Seino S
- Organizer
  2013 International Conference on Diabetes and Metabolism & 5th Asian Association for the Studies on Diabetes
- Place of Presentation
  Seoul, Korea
- Invited
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] 膵β細胞シグナリングの進化と展望
- Author(s)
  清野　進
- Organizer
  第56回日本糖尿病学会年次学術集会特別シンポジウム7：膵β細胞研究の進化と展望基調講演
- Place of Presentation
  熊本
- Invited
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] Induction of cAMP responsiveness by formation of pseudoislets.
- Author(s)
  Gheni G, Iwasaki M, Ogura M, Yokoi N, Shibasaki T, Minami K, and Seino S
- Organizer
  Beta Cell Workshop 2013 Kyoto
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] Mechanisms of cell signaling in insulin secretion.
- Author(s)
  Seino S
- Organizer
  Gordon Research Conferences 2013
- Place of Presentation
  Massachusetts, USA
- Invited
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] The role of Malate-aspartate shuttle derived glutamate in incretin potentiated insulin secretion.
- Author(s)
  Gheni G, Iwasaki M, Ogura M, Minami K, Yokoi N, Shibasaki T, Takahashi H, Sugawara K, Seino S
- Organizer
  5th International Uyghur Academy Conference 2013.10.6 (Istanbul, Turkey)
- Place of Presentation
  Istanbul, Turkey
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] Sulfonylureas act as an enhancer of Epac2 activation in cAMP-induced insulin secretion.
- Author(s)
  Takahashi T, Shibasaki T, Takahashi H, Sugawara K, Ono A, Seino S
- Organizer
  American Diabetes Association's 73rd Scientific Sessions
- Place of Presentation
  Chicago, USA
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] Cell signaling in insulin secretion: Novel mechanisms of cAMP action.
- Author(s)
  Seino S
- Organizer
  2014 Keystone Symposium on Challenges and Opportunities in Diabetes Research and Treatment
- Place of Presentation
  Vancouver, Canada
- Invited
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] Interaction of incretin and sulfonylurea through Epac2A signaling in insulin secretion
- Author(s)
  Takahashi H, Shibasaki T, Hidaka S, Ono A, Takahashi T, Seino S
- Organizer
  第56回日本糖尿病学会年次学術集会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] Induction of gastrointestinal hormones in pancreatic islets of a mouse model of beta cell regeneration.
- Author(s)
  Minami K, Kitanoya H, Takahashi H, Seino S
- Organizer
  48th Annual Meeting of the European Association for the Study of Diabetes
- Place of Presentation
  Berlin, Germany
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] Interaction of incretin and sulfonylurea through Epac2 in insulin secretion.
- Author(s)
  Takahashi H, Shibasaki T, Hidaka S, Takahashi T, Ono A, Seino S
- Organizer
  9th International Diabetes Feferation Western Pacific Region Congress/4th Scientific Meeting of the Asian Association for the Study of Diabetes
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] Epac2/Rap1を介したインスリン分泌における下流シグナルの探索
- Author(s)
  柴崎忠雄、堰千紘、髙橋晴美、清野　進
- Organizer
  第56回日本糖尿病学会年次学術集会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] Effect of liraglutide on pancreatic beta-cell mass in alloxan induced diabetic mice.
- Author(s)
  Kudo M, Minami K, Tamura K, Kitanoya H, Iemoto K, Takahashi H, and Seino S
- Organizer
  Beta Cell Workshop 2013 Kyoto
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] The signals that strengthen beta-cells: toward better understanding and treatment of diabetes.
- Author(s)
  Seino S
- Organizer
  2013 International Diabetes Federation World Diabetes Congress 2013
- Place of Presentation
  Melbourne, Australia
- Invited
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] Elucidation of the mechanisms of insulin secretion by metabolomics.
- Author(s)
  Seino S
- Organizer
  2012 International Conference on Diabetes and Metabolism
- Place of Presentation
  Seoul, Korea
- Invited
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] Search for biomarkers that predict the development of type 2 diabetes.
- Author(s)
  Yokoi N, Hoshikawa R, Beppu M, Hidaka S, Hoshino M, Shinohara M, Seino S
- Organizer
  49th Annual Meeting of the European Association for the Study of Diabetes
- Place of Presentation
  Barcelona, Spain
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] Elucidation of postnatal pancreatic beta-cell fate using Ins2-CreER/R26R-YFP double knock-in mice.
- Author(s)
  Tamura K, Minami K, Kudo M, Kitanoya H, Nakamura K, and Seino S
- Organizer
  Beta Cell Workshop 2013 Kyoto
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] New approach to the study on cell signaling in insulin secretion.
- Author(s)
  Seino S
- Organizer
  Plenary Lecture 9th International Diabetes Federation Western Pacific Region Congress/4th Scientific Meeting of the Asian Association for the Study of Diabetes
- Place of Presentation
  Kyoto, Japan
- Invited
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] Sui β-saibou shougai no bunshi kikou
- Author(s)
  Seino S
- Organizer
  Advances in Diabetology 41st Annual Post Graduate Course
- Place of Presentation
  sapporo
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002002
[Presentation] Ins2-CreER/R26R-YFPダブルノックインマウスを用いた出生後における新生膵β細胞の運命追跡
- Author(s)
  田村香楠子、南幸太郎、工藤麻耶、北野谷寿人、中村維文、家本啓佑、清野進
- Organizer
  第56回日本糖尿病学会年次学術集会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] 新規肥満性2型糖尿病モデルZucker fatty diabetes mellitus（ZFDM）ラットの確立と表現型解析
- Author(s)
  横井伯英、星野雅行、日高志保美、別府正悠、星川律子、河田昭彦、清野　進
- Organizer
  第60回日本実験動物学会総会
- Place of Presentation
  つくば
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] Regulation of actin dynamics by N-WASP and cofilin in pancreatic beta-cells and its role in insulin secretion.
- Author(s)
  Shibasaki T, Uenishi1 E, Takahashi H, Hamaguchi1 H, Oiso Y, Seino S
- Organizer
  9th International Diabetes Feferation Western Pacific Region Congress/4th Scientific Meeting of the Asian Association for the Study of Diabetes
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] 新たなインスリン分泌メカニズムと糖尿病治療薬開発における意義
- Author(s)
  清野　進
- Organizer
  関西実験動物研究会第118回研究会
- Place of Presentation
  神戸
- Invited
- Data Source
  KAKENHI-PROJECT-24229007
[Presentation] Critical Role of Actin Dynamics Regulated by N-WASP and Cofilin in the Biphasic Response of Glucose-Induced Insulin Secretion.
- Author(s)
  Shibasaki T, Uenishi E, Takahashi H, Oiso Y, Seino S
- Organizer
  American Diabetes Association's 73rd Scientific Sessions
- Place of Presentation
  Chicago, USA
- Data Source
  KAKENHI-PROJECT-24229007

1. INAGAKI Nobuya (30241954)

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2. KUROMI Hiroshi (30009633)

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3. GONOI Tohru (30134365)

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4. SHIBASAKI Tadao (00323436)

# of Collaborated Projects: 3 results

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5. SEINO Yutaka (40030986)

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6. ISHIDA Hitoshi (80212893)

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7. YOKOI Norihide (70311610)

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8. MIKI Takashi (50302568)

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9. YANO Hideki (30288576)

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10. STOFFEL Markus

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14. MAKINO Eiichi (50009578)

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19. ITO Hiroshi (00232463)

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20. KADAWAKI Takashi (30185889)

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21. OKA Yoshitomo (70175256)

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22. NANJO Kishio (40164511)

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23. TAKEDA Jun (40270855)

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24. NAKAYA Haruaki (60113594)

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25. IWANAGA Toshihiko (10160128)

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37. 北里宏 (20079700)

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38. HAYASHI Shigehiro

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39. TOKUYAMA Yoshiharu

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40. POLONSKY Kenneth S.

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41. ENDOU Kazuki

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42. THORENS Bemard

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43. BELL Graeme I.

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44. WATANABE Toshifumi

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45. JOMORI Takahito

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46. BLONDEL Oliv

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47. BLONDE Olivier

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48. 畔蒜藤一

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49. THORENS Bern

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50. GRAEME I.Bel

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51. 渡邉敏文

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52. 吉富秀幸

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53. CARMEAN CHRISTOPHER

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54. TAKAHASHI Harumi

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55. NISHIMURA Wataru

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56. HARA Kazuo

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57. HIROTA Yushi

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58. TANABE Katsuya

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59. SEINO Yusuke

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60. 河西春郎

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61. 淺原俊一郎

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62. 李恩瑛

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SEINO Susumu 清野 進

Research Projects

Research Products

Co-Researchers

糖尿病におけるβ細胞Gタンパク質シグナル変換の機序、病態生理ならびに治療応用Principal Investigator

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糖尿病のインクレチン応答性インスリン分泌不全の分子機構解明とその治療戦略の確立Principal Investigator

Principal Investigator

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ヒ素による糖代謝異常における膵α細胞の役割に関する研究Principal Investigator

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Elucidation of pancreatic beta-cell function by metabolomics and its clinical applicationPrincipal Investigator

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Mechanisms of functional expression of pancreatic islets as an integrated system and its failurePrincipal Investigator

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インスリン分泌システムの形成機構とその破綻Principal Investigator

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Formation of the integrated insulin secretion system and its failurePrincipal Investigator

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肝細胞増殖因子受容体(c-Met)を介するシグナル伝達の分子機構

Principal Investigator

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Role of cardiac ATP-sensitive K^+ channels clarified by Kir6.2-deficient mice

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Expression of Somatostatin-Receptor and Inhibitory Effect of Somatostatin on Cell Proliferation in Hepatobiliary Malignancies

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Comprehensive Analysis of Genetic Factors in Diabetes MellitusPrincipal Investigator

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A Screening System for Development of Novel Insulin SecretagoguesPrincipal Investigator

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Generation and analysis of GIP Receptor deficient mice

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SEINO Susumu 清野進