Abumiya Takeo 鐙谷武雄

… Alternative Names

ABUMIYA Takeo 鐙谷武雄

鐙谷武雄アブミヤタケオ

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Researcher Number	80270726
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Affiliation (Current)	2025: 北海道大学, 医学研究院, 客員研究員
Affiliation (based on the past Project Information) *help	2018 – 2023: 北海道大学, 医学研究院, 客員研究員 2015 – 2017: 北海道大学, 大学病院, 助教 2014: 北海道大学, 医学(系)研究科(研究院), 助教 2014: 北海道大学, 大学院医学研究科, 特任助教 2013 – 2014: 北海道大学, 医学(系)研究科(研究院), 特任助教 … More 2012: 北海道大学, 医学(系)研究科(研究院), 非常勤講師 2008 – 2010: Hokkaido University, 大学院・医学研究科, 非常勤講師 2005: 北海道大学, 北海道大学病院, 医員 1997: 国立循環器病センター研究所, 疫学部, 室員 1996 – 1997: 国立循環器病センター研究所疫学部, 室員 1995: 国立循環器病センター研究所, 疫学部, 室員 Less
Review Section/Research Field	Principal Investigator Basic Section 56010:Neurosurgery-related / Cerebral neurosurgery / Neurosurgery / Circulatory organs internal medicine Except Principal Investigator Neurosurgery / Basic Section 56010:Neurosurgery-related / Circulatory organs internal medicine / Radiation science / Cerebral neurosurgery
Keywords	Principal Investigator 脳梗塞 / 虚血再灌流傷害 / 人工酸素運搬体 / 脳保護作用 / 抗酸化物質 / 活性酸素 / 一酸化炭素 / 脳低温療法 / 虚血再灌流障害 / 冷却灌流 … More / 脳保護療法 / 低脳温治療 / ｊ虚血再灌流 / 脳低温治療 / 虚血再灌流 / 酸化ストレス / 血管内皮細胞 / 脳微小血管 / 組織因子 / マクロファージ / 高血圧 … More Except Principal Investigator もやもや病 / くも膜下出血 / iPS細胞 / 高血圧 / マクロファージ / 局所冷却療法 / デフェロキサミン / 脳虚血再灌流障害 / 虚血再灌流障害 / reperfusion injury / Ferroptosis / 脳虚血 / 脳保護 / 人工酸素運搬体HBOC / 遅発性脳血管攣縮 / 高分子合成 / トランスレーショナルリサーチ / 脳神経疾患 / ソフトマター / 塞栓物質 / X線不透過 / ソフトマターテクノロジー / CT / ラット系頸動脈投与 / 粒子塞栓物質 / X線視認性 / ハイドロゲル / hypervascular tumor / hydrogel / Intervention / embolization / biomaterial / 神経堤細胞 / 神経堤 / 血管平滑筋細胞 / 平滑筋細胞 / ニトロ化合物 / 内皮 / 血行力学的負荷 / ラット / 抗血小板剤 / 動物モデル / 大型脳動脈瘤 / 脳動脈瘤破裂 / 脳動脈瘤 / tight junction / バリア機能 / 内皮細胞 / 血管内皮細胞 / hypertension / cytokine / biglycan / decorin / extracellular matrix / smoothh muscle cell / macrophage / stent / 血管形成術 / 組織適合性抗原 / 動脈硬化 / 血管壊死 / サイトカイン / バイグリカン / デコリン / 細胞外マトリックス / 平滑筋 / ステント / インテグリンαvβ3 / インテグリンαvβ３ / 組織因子 / 低酸素イメージング / 不安定プラーク / 核医学診断 / 放射線 / SIRT1 / 細胞老化 / 脳微小血管 / Neuroprotection / Biomaterial / Migration / Differentiation / Transplantation / Bone marrow stromal cell / Spinal cord injury / Cerebral stroke / 遊走 / 分化 / 再生医療 / 移植 / 骨髄間質細胞 Less

Innovative Research of Neuroprotection for Delayed Cerebral Ischemia Associated with Cerebral Vasospasm after Subarachnoid Hemorrhage using Novel Hemoglobin-based Oxygen Carrier
- Principal Investigator
  
  月花正幸
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Hokkaido University
人工酸素運搬体を用いたmulti-targetの脳保護療法の開発Principal Investigator
- Principal Investigator
  
  鐙谷武雄
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Hokkaido University
The efficacy of novel treatment method to block Feroptosis for ischemic stroke
- Principal Investigator
  
  Kota Kurisu
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Hokkaido University
Development of neruoprotectice therapy by artificial oxygen carriier with antioxidant functionPrincipal Investigator
- Principal Investigator
  
  Abumiya Takeo
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Hokkaido University
Development of visible particle embolic material used by new concept hydrogel
- Principal Investigator
  
  Osanai Toshiya
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Hokkaido University
Development of neuroprotective therapy with selective intra-arterial infusion of cold artificial oxygen carrierPrincipal Investigator
- Principal Investigator
  
  Abumiya Takeo
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Hokkaido University
Investigation of barrier function of endothelial cells derived from moyamoya disease-specific iPS cells
- Principal Investigator
  
  KAZUMATA Ken
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Hokkaido University
Development of an anti-rupture drug treatment method using a novel animal model of easily rupturable large cerebral aneurysm and human clinical specimen
- Principal Investigator
  
  NAKAYAMA Naoki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Hokkaido University
Induction of smooth muscle cells from iPS cells derived from moyamoya disease patient
- Principal Investigator
  
  Houkin Kiyohiro
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Neurosurgery
- Research Institution
  Hokkaido University
Nuclear medicine imaging toward therapeutic strategy of atherosclerosis: Experimental research to establish EBM
- Principal Investigator
  
  KUGE Yuji
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Radiation science
- Research Institution
  Hokkaido University
The role of SIRT1 in cellular senescence and characteristics in brain microvascular endothelial cells
- Principal Investigator
  
  HOUKIN Kiyohiro
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Neurosurgery
- Research Institution
  Hokkaido University
Development of regional brain hypothremia by trans-ventricular and trans-arterial cold infusion in acute cerebral ischemiaPrincipal Investigator
- Principal Investigator
  
  ABUMIYA Takeo
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Hokkaido University
Elucidation of mechanism of increase in oxidative stress related to intrinsic susceptibility in brain microvascular endothelial cellsPrincipal Investigator
- Principal Investigator
  
  ABUMIYA Takeo
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Hokkaido University
自己骨髄細胞を利用したもやもや病に対する血管新生療法の開発
- Principal Investigator
  
  IWASAKI Yoshinobu
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Hokkaido University
Role of macrophages and extracellular matrix in vascular remodeling
- Principal Investigator
  
  MASUDA Junichi
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Shimane Medical University
高血圧による脳血管のRemodelingの機序に関する細胞・分子生物学的検討Principal Investigator
- Principal Investigator
  
  鐙谷武雄
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  National Cardiovascular Center Research Institute

All 2023 2019 2018 2017 2016 2015 2011 Other

All Journal Article Presentation

[Journal Article] Neuroprotective effects of a hemoglobin-based oxygen carrier (stroma-free hemoglobin nanoparticle) on ischemia reperfusion injury2023
- Author(s)
  Ryota Tatezawa, Takeo Abumiya, Yasuhiro Ito, Masayuki Gekka, Wataru Okamoto, Kohta Ishii, Natsumi Kohyama, Teruyuki Komatsu, Miki Fujimura
- Journal Title
  
  Brain Reseach
  
  Volume: 1821 Pages: 148592-148592
- DOI
  10.1016/j.brainres.2023.148592
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K09224
[Journal Article] Novel Hemoglobin-Based Oxygen Carrier Bound With Albumin Shows Neuroprotection With Possible Antioxidant Effects2018
- Author(s)
  Gekka Masayuki、Abumiya Takeo、Komatsu Teruyuki、Funaki Ryosuke、Kurisu Kota、Shimbo Daisuke、Kawabori Masato、Osanai Toshiya、Nakayama Naoki、Kazumata Ken、Houkin Kiyohiro
- Journal Title
  
  Stroke
  
  Volume: 49 Issue: 8 Pages: 1960-1968
- DOI
  10.1161/strokeaha.118.021467
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10708
[Journal Article] Surgical Outcome of Cerebral Aneurysm Clipping Treated with Immunosuppressants: Report of 11 Cases and Review of the Literature2017
- Author(s)
  Hokari M, Nakayama N, Kazumata K, Osanai T, Shichinohe H, Abumiya T, Houkin K.
- Journal Title
  
  Neurol. Med. Chir.(Tokyo)
  
  Volume: 57 Issue: 3 Pages: 122-127
- DOI
  10.2176/nmc.oa.2016-0185
- NAID
  130005439797
- ISSN
  0470-8105, 1349-8029
- Language
  English
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K10284, KAKENHI-PROJECT-15K10287
[Journal Article] Advanced Glycation End Products Increase Permeability of Brain Microvascular Endothelial Cells through Reactive Oxygen Species-Induced Vascular Endothelial Growth Factor Expression.2011
- Author(s)
  Niiya Y, Abumiya T, et al.
- Journal Title
  
  J Stroke Cerebrovasc Dis.
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591681
[Presentation] 新規人工酸素運搬体Hemoglobin nanoparticleの脳虚血再灌流傷害に対する神経保護効果2023
- Author(s)
  舘澤諒大, 鐙谷武雄, 伊藤康裕, 月花正幸, 岡本航, 高山夏実, 小松晃之, 藤村幹
- Organizer
  日本脳神経外科学会第82回学術総会
- Data Source
  KAKENHI-PROJECT-22K09224
[Presentation] Neuroprotective effects of a newly developed hemoglobin-based oxygen carrier (hemoglobin nanoparticle) on ischemia reperfusion injury2023
- Author(s)
  Ryota Tatezawa, Takeo Abumiya, Yasuhiro Ito, Masayuki Gekka, Wataru Okamoto, Natsumi Kohyama, Teruyuki Komatsu, Miki Fujimura
- Organizer
  Brain and Brain PET 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K09224
[Presentation] 脳虚血再灌流傷害急性期微小循環障害に対するヘモグロビン‐アルブミン複合型人工酸素運搬体HemoActの効果の検討2019
- Author(s)
  [演者] 月花正幸: [共同演者］鐙谷武雄, 小松晃之、舟木亮佑、栗栖宏多、新保大輔、伊藤康裕::, 中山若樹:, 数又研:, 寳金清博:
- Organizer
  第44回日本脳卒中学会学術集会
- Data Source
  KAKENHI-PROJECT-16K10708
[Presentation] 脳虚血再灌流傷害に対するアルブミン結合型人工酸素運搬体HemoActの脳保護効果の作用機序―微小循環・酸素運搬能改善と抗酸化作用―2018
- Author(s)
  [演者] 鐙谷武雄: [共同演者] 月花正幸, 伊藤康裕:, 川堀真人:, 長内俊也:, 中山若樹:, 数又研:, 寳金清博:
- Organizer
  日本脳神経外科学会第77回学術総会
- Data Source
  KAKENHI-PROJECT-16K10708
[Presentation] 新規人工酸素運搬体“HemoAct”を用いた脳虚血再灌流治療の開発2017
- Author(s)
  月花正幸鐙谷武雄　小松晃之　船木亮佑　栗栖宏多　中山若樹　数又研　宝金清博
- Organizer
  日本脳神経外学会第76回学術総会
- Data Source
  KAKENHI-PROJECT-16K10708
[Presentation] Neuroprotective Therapy for Ischemia-Reperfusion Injury by Hemoglobin-albumin-cluster (HemoAct)2017
- Author(s)
  Masayuki Gekka, Takeo Abumiya, Teruyuki Komatsu, Ryousuke Funaki, Kota Kurisu, Naoki Nakayama, Ken Kazumata, Hideo Shichinohe and Kiyohiro Houkin
- Organizer
  International Stroke Conference 2017
- Place of Presentation
  George R Brown Convention Center, Houston, USA
- Year and Date
  2017-02-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10708
[Presentation] 人工酸素運搬体HemoActを用いた脳虚血再灌流障害に対する脳保護療法2017
- Author(s)
  月花正幸, 鐙谷武雄, 小松晃之, 船木亮佑, 栗栖宏太, 中山若樹, 数又研, 宝金清博
- Organizer
  第42回日本脳卒中学会学術集会
- Place of Presentation
  大阪国際会議場、大阪府大阪市
- Year and Date
  2017-03-16
- Data Source
  KAKENHI-PROJECT-16K10708
[Presentation] A Novel Cerebral Aneurysm Model in Rat with Intraperitoneal BetaAminoPropioNitrilFumarate (Oral Presentation)2016
- Author(s)
  Yusuke Shimoda, Takuya Moriwaki, Naoki Nakayama, Takeo Abumiya, Ken Kazumata, Hideo Shichinohe, Kiyohiro Houkin
- Organizer
  International Stroke Conference 2016
- Place of Presentation
  Los Angeles, USA
- Year and Date
  2016-02-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10287
[Presentation] 大型脳動脈瘤モデルラットの確立へむけて（一般口演）2015
- Author(s)
  下田祐介森脇拓也中山若樹栗栖宏多穂刈正昭七戸秀夫鐙谷武雄長内俊也数又研寶金清博
- Organizer
  第74回日本脳神経外科学会学術総会
- Place of Presentation
  ロイトン札幌（北海道-札幌市）
- Year and Date
  2015-10-14
- Data Source
  KAKENHI-PROJECT-15K10287
[Presentation] Inside Intramural Thrombus Formation with Inflammatory Reactions is Relevant to the Rupture of Cerebral Aneurysms (Oral Presentation)2015
- Author(s)
  Yusuke Shimoda, Naoki NAKAYAMA, Takeo ABUMIYA, Masaaki HOKARI, Kota KURISU, Hideo SHICHINOHE, Ken KAZUMATA, Kiyohiro HOUKIN
- Organizer
  83ｒd AANS Annual Scientific Meeting
- Place of Presentation
  Washington DC, USA
- Year and Date
  2015-05-02
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10287
[Presentation] Post-ischemic trans-arterial regional hypothermia therapy attenuates microvascular narrowing due to astrocyte end-feet swelling and inhibits subsequent inflammatory reactions in ischemia reperfusion injury
- Author(s)
  Kota Kurisu, Takeo Abumiya, Hideki Nakamura, Daisuke Shimbo, Ken Kazumata, Naoki Nakayama, Hideo Shichinohe, Masaaki Hokari, Toshiya Osanai, Hiroshi Shimizu, Kiyohiro Houkin
- Organizer
  International stroke conference 2015
- Place of Presentation
  Nashville, USA
- Year and Date
  2015-02-11 – 2015-02-13
- Data Source
  KAKENHI-PROJECT-24592110
[Presentation] 虚血再灌流傷害に対する経動脈的局所低脳温治療の脳保護効果の検討―微小血管狭小化とAQP4発現への影響―
- Author(s)
  栗栖宏多、鐙谷武雄、中村秀樹、新保大輔、数又　研、中山若樹、七戸秀夫、清水　宏、宝金清博
- Organizer
  日本脳卒中学会
- Place of Presentation
  リーガロイヤルホテル広島(広島)
- Year and Date
  2015-03-26 – 2015-03-29
- Data Source
  KAKENHI-PROJECT-24592110

1. NAKAYAMA Naoki (40421961)

# of Collaborated Projects: 9 results

# of Collaborated Products: 11 results
2. HOUKIN Kiyohiro (90229146)

# of Collaborated Projects: 8 results

# of Collaborated Products: 11 results
3. KAZUMATA Ken (60634144)

# of Collaborated Projects: 7 results

# of Collaborated Products: 9 results
4. SHICHINOHE Hideo (80374479)

# of Collaborated Projects: 6 results

# of Collaborated Products: 1 results
5. Osanai Toshiya (90622788)

# of Collaborated Projects: 4 results

# of Collaborated Products: 2 results
6. 小松晃之 (30298187)

# of Collaborated Projects: 4 results

# of Collaborated Products: 8 results
7. 川堀真人 (50399870)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
8. 伊東雅基 (10399850)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
9. 藤村幹 (00361098)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
10. IWASAKI Yoshinobu (00113522)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. KURODA Satoshi (10301904)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. HIDA Kazutoshi (10238305)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. KUGE Yuji (70321958)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. MASUDA Junichi (70173747)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. Kota Kurisu (30869839)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 石川達哉 (10281809)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 東川桂 (10756878)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 川井恵一 (30204663)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 浅田祐士郎 (70202588)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 山下篤 (90372797)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 玉木長良 (30171888)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 西嶋剣一 (60364254)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 志水陽一 (90634212)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 森脇拓也 (30597464)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
25. 穂刈正昭 (30622807)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
26. 黒川孝幸 (40451439)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 杉山拓 (70748863)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 月花正幸 (40812285)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. SHIMODA Yusuke

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results

Abumiya Takeo 鐙谷 武雄

ABUMIYA Takeo 鐙谷 武雄

鐙谷 武雄 アブミヤ タケオ

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人工酸素運搬体を用いたmulti-targetの脳保護療法の開発Principal Investigator

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Development of neruoprotectice therapy by artificial oxygen carriier with antioxidant functionPrincipal Investigator

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Development of neuroprotective therapy with selective intra-arterial infusion of cold artificial oxygen carrierPrincipal Investigator

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Development of regional brain hypothremia by trans-ventricular and trans-arterial cold infusion in acute cerebral ischemiaPrincipal Investigator

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Elucidation of mechanism of increase in oxidative stress related to intrinsic susceptibility in brain microvascular endothelial cellsPrincipal Investigator

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Abumiya Takeo 鐙谷武雄

ABUMIYA Takeo 鐙谷武雄

鐙谷武雄アブミヤタケオ

[Presentation] 新規人工酸素運搬体Hemoglobin nanoparticleの脳虚血再灌流傷害に対する神経保護効果2023