KIKUCHI Hirotoshi 菊地弘敏

… Alternative Names

菊地弘敏キクチヒロトシ

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Researcher Number	80338681
Other IDs
External Links
Affiliation (Current)	2025: 帝京大学, 医療共通教育研究センター, 教授
Affiliation (based on the past Project Information) *help	2023: 帝京大学, 公私立大学の部局等, 教授 2014 – 2023: 帝京大学, 医学部, 准教授 2022: 帝京大学, 医療共通教育研究センター, 教授 2012 – 2014: 帝京大学, 医学部, 講師 2001 – 2005: Teikyo University, Internal Medicine, Assistant Professor, 医学部, 助手
Review Section/Research Field	Except Principal Investigator 内科学一般 / Basic Section 58030:Hygiene and public health-related: excluding laboratory approach / Basic Section 54020:Connective tissue disease and allergy-related / Social welfare and social work studies / 膠原病・アレルギー・感染症内科学 / Infectious disease medicine / Parasitology (including Sanitary zoology)
Keywords	Except Principal Investigator SLE / ベーチェット病 / IL-12 / luciferase / Jurkat / IFN-α / mRNA / CD154 / anti-neuronal antibody / 固相化抗CD3抗体 … More / 髄液 / 抗神経細胞抗体 / グルタミン酸レセプター / CNSループス / 遺伝子発現 / 日常生活動作 / 社会参加 / フレイル / サイトカイン / 亜型解析 / 遺伝学的解析 / 疾患レジストリ / 難病プラットフォーム / 疾患活動性指標 / GWAS / クラスター解析 / ゲノム解析 / レジストリ / 予後不良病型 / 疾患活動性 / レジストリ研究 / 社会医学 / 医療･福祉 / 心理社会的問題 / 身体的問題 / 難病 / 生活の質 / アセスメント / チェックリスト / 信頼性・妥当性評価 / 評価指標 / 身体的・心理社会的問題 / 国際生活機能分類 / lupus psychosis / epitope / anti-glutamate receptor antibody / ribosomal P proteins / cerebrospinal fluid / central nervous system / systemic lupus erythematosus / リボソームP蛋白 / リボソームP0蛋白 / エピトープ / リボソームPO蛋白 / ループス精神病 / T cell / 抗CD28抗体 / B細胞 / stability / T細胞 / cerebrospinan fluid / glutamate receptor / anti-lymphocyte antibody / monocyte / anti-ribosomal P antibody / CNS lupus / Bリンパ球 / Tリンパ球 / 抗リンパ球抗体 / 単球 / 抗リボソームP抗体 / サイトカイン産生 / 血清オプソニン活性 / 貪食能 / LAD2細胞 / 食細胞 / 家畜由来株 / TNF-α / 好中球内遺伝子発現 / リポ多糖体 / LAMP迅速診断法 / マスト細胞 / リポ多糖体（LPS) / マウス肺感染モデル / 好中球 / アシネトバクター / LAMP法 / 多剤耐性アシネトバクター / 膜小胞 / リポ多糖 / 好中球細胞外トラップ / 好中球機能 / アシネトバクター・バウマニ / inflammatory response / immunomodulator / 細胞外ヌクレオチド酵素 / 免疫調節 / 原虫 Less

内部障害を有する難病患者のフレイル実態調査
- Principal Investigator
  
  筒井秀代
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58030:Hygiene and public health-related: excluding laboratory approach
- Research Institution
  Seijoh University
Generation of evidence through registry construction by genome-wide subtype analysis of Behcet's disease
- Principal Investigator
  
  KIRINO Yohei
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Yokohama City University
Development of an assessment index for physical and psychosocial problems for intractable disease patients with internal impediment
- Principal Investigator
  
  TSUTSUI HIDEYO
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Social welfare and social work studies
- Research Institution
  Teikyo Heisei University
  Teikyo University
Immuno-modulator effects of the apyrase derived from Toxoplasma gondii
- Principal Investigator
  
  Kikuchi-Ueda Takane
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Parasitology (including Sanitary zoology)
- Research Institution
  Teikyo University
Analysis of the predisposing host factors to severe pathological conditions caused by Acinetobacter baumannii infections and the search the new virulence factors of multi-drug resistant strains
- Principal Investigator
  
  ONO YASUO
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Infectious disease medicine
- Research Institution
  Teikyo University
Role of anti-neuronal antibodies in the pathogenesis of central nervous system lupus erythematosus
- Principal Investigator
  
  HIROHATA Shunsei
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  Teikyo University School of Medicine
Molecular analysis of the abnormal expression of CD 154 in T cells as a mechanism of induction of autoinimune disease.
- Principal Investigator
  
  HIROHATA Shunsei
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  Teikyo University School of Medicine
Investigation into the roles of autoantibodies in the pathogenesis of central nervous system lupus erythematosus.
- Principal Investigator
  
  HIROHATA Shunsei
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  Teikyo University School of Medicine

All 2020 2019 2018 2016 2015 2014 2013 2004 Other

All Journal Article Presentation Other

[Journal Article] Mycobacterium heckeshornense-induced deep abscess in the gluteus maximus muscle: a case report and review of the literature.2019
- Author(s)
  Kikuchi H, Asako K, Kono K, Asahara M, Tanaka T, Kamoshida G, Ueda T, Nagakawa S, Ubagai T, Kazumi Y, Ono Y.
- Journal Title
  
  Jpn J Antibiot
  
  Volume: 72 Pages: 89-95
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K04187
[Journal Article] ベーチェット病の診断と鑑別を要する類縁疾患2018
- Author(s)
  菊地弘敏
- Journal Title
  
  膠原病診療のPearls and Myths
  
  Volume: 35 Pages: 911-915
- Data Source
  KAKENHI-PROJECT-16K04187
[Journal Article] New low-dose liquid pilocarpine formulation for treating dry mouth in Sj?gren’s syndrome: clinical efficacy, symptom relief, and improvement in quality of life2018
- Author(s)
  Watanabe Machiko、Yamada Chisato、Komagata Yoshinori、Kikuchi Hirotoshi、Hosono Hiroyuki、Itagaki Fumio
- Journal Title
  
  Journal of Pharmaceutical Health Care and Sciences
  
  Volume: 4 Issue: 1 Pages: 4-4
- DOI
  10.1186/s40780-018-0099-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K04187
[Journal Article] Improving the soluble expression and purification of recombinant human stem cell factor (SCF) in endotoxin-free Escherichia coki by disulfide shuffling with persulfide2016
- Author(s)
  Takafumi Ueda, Teruo Akuta. Takane Kikuchi-Ueda, Keitaro Imaizumi, Yasuo Ono
- Journal Title
  
  Protein Expression and Purification
  
  Volume: 120 Pages: 99-105
- DOI
  10.1016/j.pep.2015.12.015
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24590512
[Journal Article] Expression of bioactive soluble human stem cell factor (SCF) from recombinant Escherichia coli by coproduction of thioredoxin and efficient purification using arginine in affinity chromatography2015
- Author(s)
  Teruo Akuta, Takane Kikuchi-Ueda, Keitaro Imaizumi, Hiroyuki Oshikane, Toshio Nakaki, Yoko Okada, Sara Sultana, Kenichiro Kobayashi, Nobutaka Kiyokawa, Yasuo Ono
- Journal Title
  
  Protein Expression and Purification
  
  Volume: 105 Pages: 1-7
- DOI
  10.1016/j.pep.2014.09.015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590512
[Journal Article] Inhibitory effects of bucillamine on the expression of vascular cell adhesion molecule-1 in human umbilical vein endothelial cells.2004
- Author(s)
  Kikuchi H, Isshi K, Hirohata S
- Journal Title
  
  Int Immunopharm 4
  
  Pages: 119-126
- Data Source
  KAKENHI-PROJECT-16590996
[Journal Article] 特集:血管炎をきたす疾患の鑑別診断と治療中枢神経系に血管炎をきたす疾患2004
- Author(s)
  広畑俊成, 菊地弘敏
- Journal Title
  
  リウマチ科 31
  
  Pages: 447-451
- Data Source
  KAKENHI-PROJECT-16590996
[Presentation] 疲労感を有するベーチェット病患者の身体的・心理社会的問題点の特徴2020
- Author(s)
  筒井秀代、小口洋子、菊地弘敏
- Organizer
  第64回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-16K04187
[Presentation] ベーチェット病の最新の話題を紐解く～ベーチェット病特殊病型の診断と治療～2019
- Author(s)
  菊地弘敏
- Organizer
  第63回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-16K04187
[Presentation] リウマチ性疾患のガイドラインベーチェット病診療ガイドライン2019
- Author(s)
  岳野光洋, 廣畑俊成, 菊地弘敏, 桑名正隆, 齋藤和義, 田中良哉, 永渕裕子, 沢田哲治, 東野俊洋, 桐野洋平, 吉見竜介, 土橋浩章, 山口賢一, 金子佳代子, 伊藤秀一, 竹内正樹, 石ヶ坪良明, 水木信久
- Organizer
  第63回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-16K04187
[Presentation] 関節症状を有するベーチェット病患者の臨床特徴2019
- Author(s)
  東野俊洋, 廣畑俊成, 菊地弘敏, 沢田哲治, 岳野光洋, 永渕裕子, 桐野洋平, 宮川一平, 田中良哉, 山岡邦宏
- Organizer
  第63回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-16K04187
[Presentation] The Long-term Outcome of patients with arthritis of Behcet’s disease.2019
- Author(s)
  Kikuchi H, Tomizuka T, Asako K, Kono H, Hirohata S
- Organizer
  American College of Rheumatology (ACR) Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K04187
[Presentation] Strong association of HLA-DRB1*0901 with Japanese patients with chronic progressive neuro-Behcet’s disease.2019
- Author(s)
  Kikuchi H, Hirohata S
- Organizer
  第60回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-16K04187
[Presentation] 慢性進行型神経ベーチェット病におけるMHC classⅡの検討2019
- Author(s)
  菊地弘敏、板宮孝紘、浅子来美、河野肇、廣畑俊成
- Organizer
  第3回日本ベーチェット病学会
- Data Source
  KAKENHI-PROJECT-16K04187
[Presentation] ベーチェット病に8 Trisomyを有するMDSを合併する症例の臨床的特徴における文献的検討2019
- Author(s)
  板宮孝紘, 冨塚崇史, 浅子来美, 津久井大輔, 木村佳貴, 菊地弘敏, 小口洋子, 本田善一郎, 竹内明輝, 河野肇
- Organizer
  第63回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-16K04187
[Presentation] 罹病期間がベーチェット病患者の生活の質(QOL)に与える影響2018
- Author(s)
  芝景司、星野裕明、深沢豪俊、小口洋子、菊地弘敏、筒井秀代
- Organizer
  第62回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-16K04187
[Presentation] リンパ増殖性疾患合併によりメトトレキサートが使用不能となった関節リウマチ症例におけるその後の治療に関しての検討2018
- Author(s)
  板宮孝紘, 浅子来美, 菊地弘敏, 木村佳貴, 津久井大輔, 本田善一郎, 竹内明輝, 小口洋子, 河野肇
- Organizer
  第62回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-16K04187
[Presentation] 膠原病患者における非結核性抗酸菌の保菌、発症状況の推移2018
- Author(s)
  北沢貴利, 三須恵太, 妹尾和憲, 吉野友祐, 菊地弘敏, 太田康男, 河野肇, 浅子来美
- Organizer
  第66回日本化学療法学会総会
- Data Source
  KAKENHI-PROJECT-16K04187
[Presentation] ベーチェット病患者のQOLに影響を及ぼす症状の検討2018
- Author(s)
  星野裕明、深沢豪俊、芝景司、小口洋子、菊地弘敏、筒井秀代
- Organizer
  第62回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-16K04187
[Presentation] 罹病期間がベーチェット病患者の生活の質 (QOL) に与える影響2018
- Author(s)
  芝景司、星野裕明、深沢豪俊、小口洋子、菊地弘敏、筒井秀代
- Organizer
  第62回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-16K04187
[Presentation] Acinetobacter baumanniiのマスト細胞上への結合標的分子の解析2018
- Author(s)
  上田たかね, 鴨志田剛, 祖母井庸之, 西田智, 永川茂, 中野竜一, 中野章代, 菊地弘敏, 斧康雄
- Organizer
  第66回日本化学療法学会総会
- Data Source
  KAKENHI-PROJECT-16K04187
[Presentation] 慢性進行型神経ベーチェット病の治療中に発症したメトトレキサート関連リンパ増殖性疾患の3例2018
- Author(s)
  菊地弘敏, 板宮孝紘, 浅子来美, 廣畑俊成, 河野肇
- Organizer
  第62回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-16K04187
[Presentation] ヒトにおける尿酸降下療法の炎症抑制効果の検討2018
- Author(s)
  木村佳貴, 柳田たみ子, 津久井大輔, 浅子来美, 菊地弘敏, 河野肇
- Organizer
  第62回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-16K04187
[Presentation] ヒトにおける尿酸降下療法の炎症抑制効果の検討2018
- Author(s)
  木村佳貴, 柳田たみ子, 津久井大輔, 浅子来美, 菊地弘敏, 河野肇
- Organizer
  第50回日本動脈硬化学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-16K04187
[Presentation] 眼症状のあるベーチェット病患者の身体的・心理社会的問題点の抽出2018
- Author(s)
  筒井秀代、小口洋子、菊地弘敏
- Organizer
  第62回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-16K04187
[Presentation] 当院における全身性エリテマトーデスに対するミコフェノール酸モフェチルの使用実態2018
- Author(s)
  浅子来美, 板宮孝紘, 木村佳貴, 菊地弘敏, 本田善一郎, 竹内明輝, 河野肇
- Organizer
  第62回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-16K04187
[Presentation] 眼症状のあるベーチェット病患者の身体的・心理社会的問題点の抽出2018
- Author(s)
  筒井秀代, 小口洋子, 菊地弘敏
- Organizer
  第62回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-16K04187
[Presentation] 全身性血管炎患者血清における抗モエシン抗体の臨床的意義2018
- Author(s)
  内田俊也, 河野肇, 浅子来美, 菊地弘敏, 本間文佳, 豊城大悟, 古西純子, 奈倉倫人, 山崎ちひろ, 兒島憲一郎, 藤垣嘉秀, 鈴木和男
- Organizer
  第61回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-16K04187
[Presentation] SLE・抗リン脂質抗体症候群6 自己抗体はびまん性精神・神経心理学的症状を呈した全身性エリテマトーデス患者における長期予後に影響を与える2018
- Author(s)
  有沼良幸, 菊地弘敏, 廣畑俊成
- Organizer
  第62回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-16K04187
[Presentation] ベーチェット病患者の生活の質 (QOL) における性差の検討2018
- Author(s)
  深沢豪俊、芝景司、星野裕明、小口洋子、菊地弘敏、筒井秀代
- Organizer
  第62回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-16K04187
[Presentation] Acinetobacter baumanniiに対するヒト由来マスト細胞株の応答(2)2014
- Author(s)
  上田たかね, 祖母井庸之, 中野竜一, 鴨志田剛, 中野章代, 永川茂, 菊地弘敏, 斧康雄
- Organizer
  第88回日本感染症学会学術講演会、第62回日本化学療法学会総会合同学会
- Place of Presentation
  福岡市
- Year and Date
  2014-06-18
- Data Source
  KAKENHI-PROJECT-24591490
[Presentation] Acinetobacter baumanniiに対するヒト由来マスト細胞株の応答2013
- Author(s)
  上田たかね　沐暁芹、祖母井庸之、中野竜一、丹生茂、菊地弘敏、斧康雄
- Organizer
  第87回日本感染症学会学術講演会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-24590512
[Presentation] Acinetobacter baumanniiに対するヒト由来マスト細胞株の応答2013
- Author(s)
  上田たかね、祖母井　庸之、中野　竜一、丹生　茂、菊地　弘敏、斧　康雄
- Organizer
  第87回日本感染症学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24591490
[Presentation] Acinetobacter baumannii に対するヒト由来マスト細胞株の応答(2)
- Author(s)
  上田たかね、祖母井庸之、中野竜一、鴨志田剛、中野章代、永川茂、菊地弘敏、斧康雄
- Organizer
  第88回日本感染症学会学術講演会・第62回日本化学療法学会総会　合同学会
- Place of Presentation
  福岡（ヒルトン福岡シーホーク）
- Year and Date
  2014-06-18 – 2014-06-20
- Data Source
  KAKENHI-PROJECT-24590512
[Presentation] NETs形成に着目した好中球のアシネトバクターと緑膿菌に対する生体防御反応の差異
- Author(s)
  鴨志田剛, 上田たかね, 永川茂, 中野竜一, 祖母井庸之, 菊地弘敏, 斧康雄
- Organizer
  第88回日本感染症学会学術講演会、第62回日本化学療法学会総会合同学会
- Place of Presentation
  福岡市
- Year and Date
  2014-06-18 – 2014-06-20
- Data Source
  KAKENHI-PROJECT-24591490
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1. HIROHATA Shunsei (90189895)

# of Collaborated Projects: 4 results

# of Collaborated Products: 2 results
2. Kikuchi-Ueda Takane (80459312)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
3. ONO Yasuo (10177272)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
4. UBAGAI Tsuneyuki (10311416)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
5. MIYASHITA Taku (00239401)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. TSUTSUI HIDEYO (30569330)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
7. NAGAKAWA Shigeru (50266300)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. NAKANO Ryuichi (80433712)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
9. GO Kamoshida (40707410)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
10. AKIYO Nakano (10707441)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
11. HIROSE Naoto (60261971)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
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KIKUCHI Hirotoshi 菊地 弘敏

菊地 弘敏 キクチ ヒロトシ

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[Journal Article] Mycobacterium heckeshornense-induced deep abscess in the gluteus maximus muscle: a case report and review of the literature.2019

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[Journal Article] ベーチェット病の診断と鑑別を要する類縁疾患2018

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[Journal Article] New low-dose liquid pilocarpine formulation for treating dry mouth in Sj?gren’s syndrome: clinical efficacy, symptom relief, and improvement in quality of life2018

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[Journal Article] Improving the soluble expression and purification of recombinant human stem cell factor (SCF) in endotoxin-free Escherichia coki by disulfide shuffling with persulfide2016

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[Journal Article] Expression of bioactive soluble human stem cell factor (SCF) from recombinant Escherichia coli by coproduction of thioredoxin and efficient purification using arginine in affinity chromatography2015

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[Journal Article] Inhibitory effects of bucillamine on the expression of vascular cell adhesion molecule-1 in human umbilical vein endothelial cells.2004

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[Journal Article] 特集:血管炎をきたす疾患の鑑別診断と治療 中枢神経系に血管炎をきたす疾患2004

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[Presentation] 疲労感を有するベーチェット病患者の身体的・心理社会的問題点の特徴2020

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KIKUCHI Hirotoshi 菊地弘敏

菊地弘敏キクチヒロトシ

[Journal Article] 特集:血管炎をきたす疾患の鑑別診断と治療中枢神経系に血管炎をきたす疾患2004

[Presentation] リウマチ性疾患のガイドラインベーチェット病診療ガイドライン2019