Kakuta Shigeru 角田茂

… Alternative Names

KAKUTA Shigeru 角田茂

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Researcher Number	80345032
Other IDs	https://orcid.org/0000-0002-5900-1425
External Links
Affiliation (Current)	2025: 東京大学, 大学院農学生命科学研究科(農学部), 准教授
Affiliation (based on the past Project Information) *help	2016 – 2024: 東京大学, 大学院農学生命科学研究科(農学部), 准教授 2017: 東京大学, 医科学研究所, 准教授 2017: 東京大学, 医科学研究所, 助教 2012 – 2015: 東京大学, 農学生命科学研究科, 准教授 2014: 東京大学, 大学院農学生命科学研究科, 准教授 … More 2011: 信州大学, 医学部, 助教 2010 – 2011: 信州大学, ヒト環境科学研究支援センター, 助教 2007 – 2009: The University of Tokyo, 医科学研究所, Assistant Professor 2002 – 2006: The University of Tokyo, Institute of Medical Science, Research Associate, 医科学研究所, 助手 Less
Review Section/Research Field	Principal Investigator Laboratory animal science / Medium-sized Section 42:Veterinary medical science, animal science, and related fields / Biological Sciences / Biological Sciences Except Principal Investigator Biological Sciences / Basic Section 42020:Veterinary medical science-related / Veterinary medical science / Experimental pathology / Laboratory animal science / Medium-sized Section 38:Agricultural chemistry and related fields … More / Basic Section 38020:Applied microbiology-related / Basic Section 42040:Laboratory animal science-related / Basic Section 42030:Animal life science-related / Medium-sized Section 49:Pathology, infection/immunology, and related fields / Integrative animal science / Complex Systems Disease Theory / Laboratory animal science / Food science / Immunology / Laboratory animal science / General medical chemistry Less
Keywords	Principal Investigator 疾患モデル / 炎症 / サイトカイン / ウイルス感染 / インターフェロン / オリゴアデニル酸 / ノックアウトマウス / 免疫機能 / 定着能向上大腸菌 / プロバオイティクス … More / プロバイオティクス / バイオフィルム / 消化管定着 / 腸内細菌 / RNA代謝 / 遺伝子欠損マウス / オートファジー / 免疫異常 / マクロファージ / リボヌクレアーゼ / インターロイキン / 疾患モデル動物 / 生理活性 / 糖鎖 / 微生物 / 癌 / IL-1 / IL-17 / 大腸がん / 樹状細胞 / T細胞 / 腫瘍免疫 / C型レクチン / 炎症性疾患 / 発生工学 / マウス / 感染防御 / ウイルス / Cre-loxPシステム / 2'5'-オリゴアデニル酸 … More Except Principal Investigator ノックアウトマウス / サイトカイン / 関節リウマチ / 疾患モデル動物 / トランスジェニックマウス / 自己免疫疾患 / 遺伝子改変マウス / 自然免疫 / マウス / C型レクチン / マイクロアレイ / 樹状細胞 / IL-1 / ゲノム編集 / Th17 / 炎症性疾患 / 自己免疫 / 疾患モデルマウス / 腸管免疫 / 発生工学 / アミロイド / ApoA-II / アミロイドーシス / 獲得免疫 / 連鎖解析 / 免疫学 / ゲノム / 霊長類 / オルガノイド / 味細胞 / 有用細菌 / プロバイオティクス / バイオフィルム / リボソーム / リボヌクレアーゼ / 免疫細胞 / 腫瘍微小環境 / 抗腫瘍免疫 / 化学療法耐性 / 不均一性 / CRISPR-Cas / 疾患モデル / 自然免疫受容体 / Dectin-1 / C型レクチン受容体 / 腸内細菌叢 / 炎症性腸疾患 / 腫瘍免疫 / 粘膜免疫 / 遺伝子欠損マウス作製 / 温度ストレス / 個体の生存 / 動物 / 熱耐性 / HSF1 / 系統化成功 / 変異型マウス / 温熱ストレス / 熱ショック転写因子 / IL-1 receptor antagonist / IL-1 signal / negative selection / 免疫 / 内科 / 病態 / macrophage / AIM / 腫瘍 / アポトーシス / 組織球 / LHパルス / サージジェネレーター / パルスジェネレーター / GCaMP / GnRH / Cyclooxygenase / GnRHニューロン / GnRHサージ / プロスタグランジン / in vivo 脳内蛍光顕微鏡 / 神経興奮 / GnRHmニューロン / 翻訳産物 / tRNA / 非開始コドン / ストレス応答 / タンパク質合成 / 非AUGコドン / ストレス / バイオマーカー / マウスモデル / トランスジェニック / 遺伝子治療 / miRNA / ノックダウン / トル様レセプター３: TLR３) / トル様レセプター3: TLR3 / 小腸常在菌 / インターフェロンβ / 食品機能 / 抗炎症 / インターロイキン-12 / インターフェロン-β / トル様レセプター３ (TLR３) / 乳酸菌 / oral tolerance / Th1 / Peyer's patch / dendritic cell / anti-inflammation / small intestine / intreferon-beta / lactic acid bacteria / 神経堤幹細胞 / 上皮系幹細胞 / 毛包幹細胞 / バルジ領域 / 幹細胞 / ネスチン / 毛包 / Innate immunity / Autoimmune / C-type lectin / Dendritic Cells / Inflmmation / Rheumatiod arthritis / cvtokine / Animal disease models / Genetic altered animals / Knockout / Embryonic Srem cell / キメラマウス / 遺伝子改変動物 / ノックアウト / ES細胞 / 癌 / IL-33シグナル / ダブルノックアウトマウス / 炎症 / 糖鎖 / 胃癌 / フォスファターゼ / 気管 / 消化管 / 血管 / ホスファターゼ / がん / 収縮蛋白 / 高血圧 / CPI-17 / リン酸化 / ミオシン / 平滑筋 / プロテオーム / 恒常性 / タンパク質 / 凝集体 / プロテオーム解析 / 蛋白質 / 質量分析 / 老化 / 加齢医学 / ApoA-I / コレステロール / 小胞体ストレス / SAA / 治療 / Apolipoprotein A-II / 線維形成 / 伝播 / 感染免疫 / 真菌感染 / Th17鈿胞 / 間接リウマチ / Th17細胞 / 自己応答性 / IL-17F / IL-17A / 慢性関節リウマチ / IL-17 / 生体防御 / 細菌感染 / siRNA / データベース / 再プログラム化 / 初期胚 / Nanog / 4 / Oct-3 / 多能性 / 神経幹細部 / 遺伝子 / シグナル伝達 / 発生・分化 / 再生医学 / HTLV-I / 病態モデル動物 / ウイルス Less

Elucidation of a novel oral immune system led by taste cells
- Principal Investigator
  
  岩槻健
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 38:Agricultural chemistry and related fields
- Research Institution
  Tokyo University of Agriculture
Mechanisms of autoimmunity induced by excess IL-1 signaling
- Principal Investigator
  
  岩倉洋一郎
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 49:Pathology, infection/immunology, and related fields
- Research Institution
  The University of Tokyo
細菌の定着性強化に向けた基盤技術創製ーバイオフィルム形成に学ぶー
- Principal Investigator
  
  小川哲弘
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 38020:Applied microbiology-related
- Research Institution
  The University of Tokyo
Analysis of mammalian survival mechanism under stressed temperature using novel mutant-HSF1 knock-in mice
- Principal Investigator
  
  林田直樹
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42030:Animal life science-related
- Research Institution
  Yamaguchi University
Investigations of the relationship between antitumor immunity and chemotherapy resistance focusing on heterogeneity in tumor tissues
- Principal Investigator
  
  富安博隆
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 42020:Veterinary medical science-related
- Research Institution
  The University of Tokyo
Development of novel technology for regulating biological functions via colonization-improved E. coli: in vivo trial using disease model animalPrincipal Investigator
- Principal Investigator
  
  角田茂
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 42:Veterinary medical science, animal science, and related fields
- Research Institution
  The University of Tokyo
Generation of gene-modified mice by targeting on innate immune receptor family and analysis of the function of these receptors by using human disease-models.
- Principal Investigator
  
  TANG CE
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 42040:Laboratory animal science-related
- Research Institution
  Tokyo University of Science
Generation and analysis of disease model mice with multiple phenotypes caused by disorder in RNA metabolism.Principal Investigator
- Principal Investigator
  
  Kakuta Shigeru
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 42:Veterinary medical science, animal science, and related fields
- Research Institution
  The University of Tokyo
AIM expression, mutation and function in canine histiocytic sarcoma
- Principal Investigator
  
  Yonezawa Tomohiro
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 42020:Veterinary medical science-related
- Research Institution
  The University of Tokyo
in vivo fluorescence imaging research on the possible role of prostaglandins in modulation of GnRH secretion
- Principal Investigator
  
  Matsuwaki Takashi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Integrative animal science
- Research Institution
  The University of Tokyo
The proposal of novel experimental system using original knockdown methods in mice
- Principal Investigator
  
  OHTSUKA Masato
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory animal science
- Research Institution
  Tokai University
Comprehensive analysis of non-AUG translation products induced by stress for the investigation of new biomarkers
- Principal Investigator
  
  Ogawa Tetsuhiro
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Complex Systems Disease Theory
- Research Institution
  The University of Tokyo
Time series analysis of unknown differentiation mechanisms and related genes for hair follicle generation
- Principal Investigator
  
  Nishifuji Koji
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Veterinary medical science
- Research Institution
  Tokyo University of Agriculture and Technology
Anti-inflammatory mechanism from small intestine to whole body via interferon-beta
- Principal Investigator
  
  Tsuji Noriko
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Food science
- Research Institution
  National Institute of Advanced Industrial Science and Technology
Clarification of new pathophysiological functions of CPI-17, an endogenous myosin phosphatase inhibitory protein.
- Principal Investigator
  
  HORI Masatoshi
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Veterinary medical science
- Research Institution
  The University of Tokyo
Role of IL-33 on gastric cancer development -Analysis using new model mice-
- Principal Investigator
  
  NAKAYAMA Jun
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Experimental pathology
- Research Institution
  Shinshu University
Generation of novel inflammatory disease model caused by dysregulation of IL-1 signalingPrincipal Investigator
- Principal Investigator
  
  KAKUTA Shigeru
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory animal science
- Research Institution
  The University of Tokyo
Ｃ型レクチン受容体を介した炎症制御と腸管ポリープ形成の解析Principal Investigator
- Principal Investigator
  
  角田茂
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
  Shinshu University
Pathological Investigation of the Pathogenesis and Development of Preventive and Therapeutic Procedures for Amyloidosis
- Principal Investigator
  
  HIGUCHI Keiichi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Experimental pathology
- Research Institution
  Shinshu University
Comprehensive Proteome Analysis of Age-related Changes in Amyloid Like Aggregates
- Principal Investigator
  
  HIGUCHI Keiichi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General medical chemistry
- Research Institution
  Shinshu University
Analysis of IL-1/IL-17 system-dependent promoting mechanisms for development of colon cancer using model micePrincipal Investigator
- Principal Investigator
  
  KAKUTA Shigeru
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Laboratory animal science
- Research Institution
  Shinshu University
真菌感染防御におけるC型レクチンの役割
- Principal Investigator
  
  西城忍
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Chiba University
  The University of Tokyo
炎症性サイトカインとC型レクチンによる発がん制御機構の解析Principal Investigator
- Principal Investigator
  
  角田茂
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Establishment of an IL-1-related gene-manipulated mice library, aiming at uncovering pathophysiology of disease from a view point of systems biology
- Principal Investigator
  
  IWAKURA Yoichiro
- Project Period (FY)
  2008 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Laboratory animal science
- Research Institution
  The University of Tokyo
疾患のシステム的理解を目指したIL-1関連遺伝子欠損マウスライブラリーの作製
- Principal Investigator
  
  岩倉洋一郎
- Project Period (FY)
  2008
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Laboratory animal science
- Research Institution
  The University of Tokyo
インターロイキン17/17Fによる細菌感染防御機構の解析
- Principal Investigator
  
  岩倉洋一郎
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
The roles of cytokines in the development of autoimmune deseases
- Principal Investigator
  
  IWAKURA Yoichiro
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
遺伝子欠損マウスを用いたオリゴアデニル酸合成酵素の生理機能の解析Principal Investigator
- Principal Investigator
  
  角田茂
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Laboratory animal science
- Research Institution
  The University of Tokyo
自己免疫性関節炎発症における樹状細胞の役割
- Principal Investigator
  
  岩倉洋一郎
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Roles of dendritic cells in the development of autoimmune arthropathy
- Principal Investigator
  
  IWAKURA Yoichiro
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Immunology
- Research Institution
  The University of Tokyo
関節リウマチの遺伝的要因の解析
- Principal Investigator
  
  岩倉洋一郎
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
自己免疫性関節炎発症における樹状細胞の役割
- Principal Investigator
  
  岩倉洋一郎
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
発生工学的手法を用いた2',5'-オリゴアデニル酸合成酵素遺伝子の機能解析Principal Investigator
- Principal Investigator
  
  角田茂
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Laboratory animal science
- Research Institution
  The University of Tokyo
慢性関節リウマチの遺伝的要因の解析
- Principal Investigator
  
  IWAKURA Yoichiro
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
HTLV-Iによる自己免疫性慢性関節炎発症機構の解明
- Principal Investigator
  
  岩倉洋一郎
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
体細胞初期化誘導および未分化維持に関するシグナル因子の解析Principal Investigator
- Principal Investigator
  
  角田茂, 須藤カツ子
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Establishment of ES cell lines derived from several inbred strains
- Principal Investigator
  
  SUDO Katsuko
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory animal science
- Research Institution
  The University of Tokyo

[Book] 真菌免疫応答におけるC型レクチン受容体の役割2012
- Author(s)
  角田茂、西城忍
- Publisher
  化学療法の領域
- Data Source
  KAKENHI-PROJECT-20220009
[Book] 遺伝子改変動物.新しい薬学事典2012
- Author(s)
  角田茂、岩倉洋一郎
- Publisher
  朝倉書店(印刷中)
- Data Source
  KAKENHI-PROJECT-20220009
[Book] IL-1. seriesモデル動物利用マニュアル免疫疾患-疾患モデルの作製と利用2011
- Author(s)
  角田茂、岩倉洋一郎
- Publisher
  エル・アイ・シー
- Data Source
  KAKENHI-PROJECT-20220009
[Book] リウマチ.論文ができてしまう!疾患モデルマウス表現型解析指南2011
- Author(s)
  角田茂
- Publisher
  中山書店
- Data Source
  KAKENHI-PROJECT-20220009
[Book] コンディショナルターゲティング法改訂第5版新2010
- Author(s)
  角田茂
- Publisher
  遺伝子工学ハンドブック
- Data Source
  KAKENHI-PROJECT-20220009
[Book] アグリゲーション法によるキメラマウスの作製改訂第5版新2010
- Author(s)
  角田茂
- Publisher
  遺伝子工学ハンドブック
- Data Source
  KAKENHI-PROJECT-20220009
[Book] アグリゲーション法によるキメラマウスの作製.改訂第5版新遺伝子工学ハンドブック2010
- Author(s)
  角田茂、佐藤希、久保幸子、岩倉洋一郎
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] Improved Genome Editing via Oviductal Nucleic Acids Delivery (i-GONAD): Protocol Steps and Additional Notes2023
- Author(s)
  Sato Masahiro、Nakamura Ayaka、Sekiguchi Marie、Matsuwaki Takashi、Miura Hiromi、Gurumurthy Channabasavaiah B.、Kakuta Shigeru、Ohtsuka Masato
- Journal Title
  
  Methods Mol Biol
  
  Volume: 2631 Pages: 325-340
- DOI
  10.1007/978-1-0716-2990-1_14
- ISBN
  9781071629895, 9781071629901
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K18229
[Journal Article] Heat Shock Transcription Factor 2 Is Significantly Involved in Neurodegenerative Diseases, Inflammatory Bowel Disease, Cancer, Male Infertility, and Fetal Alcohol Spectrum Disorder: The Novel Mechanisms of Several Severe Diseases.2022
- Author(s)
  Tokunaga Y, Otsuyama KI, Kakuta S, Hayashida N.
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 23 Issue: 22 Pages: 13763-13763
- DOI
  10.3390/ijms232213763
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06044
[Journal Article] Insights on the Functional Role of Beta-Glucans in Fungal Immunity Using Receptor-Deficient Mouse Models2021
- Author(s)
  Desamero MJM, Chung SH, Kakuta S
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22(9) Issue: 9 Pages: 4778-4778
- DOI
  10.3390/ijms22094778
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19265
[Journal Article] Effector memory CD4+T cells in mesenteric lymph nodes mediate bone loss in food-allergic enteropathy model mice, creating IL-4 dominance2021
- Author(s)
  Ono-Ohmachi Aiko、Udagawa Nobuyuki、Nakamichi Yuko、Koide Masanori、Nakajima-Adachi Haruyo
- Journal Title
  
  Mucosal Immunology
  
  Volume: 14 Issue: 6 Pages: 1335-1346
- DOI
  10.1038/s41385-021-00434-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22729, KAKENHI-PROJECT-20H03176, KAKENHI-PROJECT-20H03471, KAKENHI-PROJECT-20H03872, KAKENHI-PROJECT-21H02394, KAKENHI-PROJECT-19K22728, KAKENHI-PROJECT-20K21689, KAKENHI-PROJECT-21K16389, KAKENHI-PROJECT-19KK0234, KAKENHI-PROJECT-23K21488, KAKENHI-PROJECT-21K18229, KAKENHI-PROJECT-18K19265
[Journal Article] A Vaspin-HSPA1L complex protects proximal tubular cells from organelle stress in diabetic kidney disease2021
- Author(s)
  Nakatsuka A, Yamaguchi S, Eguchi J, Kakuta S, Iwakura Y, Sugiyama H, Wada J.
- Journal Title
  
  Commun Biol .
  
  Volume: 4 Issue: 1 Pages: 373-373
- DOI
  10.1038/s42003-021-01902-y
- NAID
  120007004153
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08608, KAKENHI-PROJECT-20K08908, KAKENHI-PUBLICLY-20H04954, KAKENHI-PROJECT-18H02671, KAKENHI-PROJECT-19H03675, KAKENHI-PROJECT-19K17984, KAKENHI-PROJECT-20H03176, KAKENHI-PROJECT-19K08679
[Journal Article] Effects of orally administered Euglena gracilis and its reserve polysaccharide, paramylon, on gastric dysplasia in A4gnt knockout mice2021
- Author(s)
  Iida M, Desamero MJ, Yasuda K, Nakashima A, Suzuki K, Chambers JK, Uchida K, Ogawa R, Hachimura S, Nakayama J, Kyuwa S, Miura K, Kakuta S, Hirayama K
- Journal Title
  
  Scientific Reports
  
  Volume: 11(1) Issue: 1 Pages: 13640-13640
- DOI
  10.1038/s41598-021-92013-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19265
[Journal Article] 研究室・施設便り「東京大学大学院農学生命科学研究科獣医学専攻実験動物学研究室」2020
- Author(s)
  角田　茂
- Journal Title
  
  実験動物ニュース
  
  Volume: 69 (1) Pages: 16-21
- Open Access
- Data Source
  KAKENHI-PROJECT-18K19265
[Journal Article] Involvement of interleukin-1 type 1 receptors in lipopolysaccharide-induced sickness responses.2017
- Author(s)
  Matsuwaki T, Shionoya K, Ihnatko R, Eskilsson A, Kakuta S, Dufour S, Schwaninger M, Waisman A, Muller W, Pinteaux E, Engblom D, Blomqvist A.
- Journal Title
  
  Brain, behavior, and immunity
  
  Volume: 66 Pages: 165-176
- DOI
  10.1016/j.bbi.2017.06.013
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03931
[Journal Article] Visualization of Probiotic-Mediated Ca2+ Signaling in Intestinal Epithelial Cells In Vivo.2016
- Author(s)
  *Adachi T, Kakuta S, Aihara Y, Kamiya T, Watanabe Y, Osakabe N, Hazato N, Miyawaki A, Yoshikawa S, Usami T, Karasuyama H, Kimoto-Nira H, *Hirayama K, *Tsuji NM.
- Journal Title
  
  Front Immunol.
  
  Volume: 7 Pages: 601-601
- DOI
  10.3389/fimmu.2016.00601
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H04504, KAKENHI-PROJECT-15K08526
[Journal Article] Exacerbation of experimental autoimmune encephalomyelitis in mice deficient for DCIR, an inhibitory C-type lectin receptor.2015
- Author(s)
  Seno A, Maruhashi T, Kaifu T, Yabe R, Fujikado N, Ma G, Ikarashi T, Kakuta S, Iwakura Y.
- Journal Title
  
  Exp Anim.
  
  Volume: 印刷中
- NAID
  130005069862
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24500488
[Journal Article] CCR8 regulates contact hypersensitivity by restricting cutaneous dendritic cell migration to the draining lymph nodes.2015
- Author(s)
  Yabe R, Shimizu K, Shimizu S, Azechi S, Choi BI, Sudo K, Kubo S, Nakae S, Ishigame H, Kakuta S, Iwakura Y.
- Journal Title
  
  Int Immunol.
  
  Volume: 27(4) Issue: 4 Pages: 169-181
- DOI
  10.1093/intimm/dxu098
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24500488, KAKENHI-PROJECT-26461961
[Journal Article] IL-1 receptor 1 antagonist-deficient mice develop autoimmune arthritis due to intrinsic activation of IL-17-producing CCR2+Vγ6+γδ T cells2015
- Author(s)
  Akitsu A, Ishigame H, Kakuta S, Chung S, Ikeda S, Shimizu K, Kubo S, Liu Y, Umemura M, Matsuzaki G, Yoshikai Y, Saijo S, Iwakura Y.
- Journal Title
  
  Nat Commun.
  
  Volume: 印刷中
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24500488
[Journal Article] IL-1 Receptor Type 2 Suppresses Collagen-Induced Arthritis by Inhibiting IL-1 Signal on Macrophages.2015
- Author(s)
  Shimizu K, Nakajima A, Sudo K, Liu Y, Mizoroki A, Ikarashi T, Horai R, Kakuta S, Watanabe T, Iwakura Y.
- Journal Title
  
  J Immunol.
  
  Volume: 194(7) Issue: 7 Pages: 3156-3168
- DOI
  10.4049/jimmunol.1402155
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24500488, KAKENHI-PROJECT-26461961, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011
[Journal Article] Chemokine Receptor CCR8 Is Required for Lipopolysaccharide-Triggered Cytokine Production in Mouse Peritoneal Macrophages.2014
- Author(s)
  Oshio T, Kawashima R, Kawamura YI, Hagiwara T, Mizutani N, Okada T, Otsubo T, Inagaki-Ohara K, Matsukawa A, Haga T, Kakuta S, Iwakura Y, Hosokawa S, Dohi T.
- Journal Title
  
  PLoS One
  
  Volume: 9(4) Issue: 4 Pages: 1-12
- DOI
  10.1371/journal.pone.0094445
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24500488, KAKENHI-PROJECT-25461026
[Journal Article] Rag2-deficient IL-1 Receptor Antagonist-deficient Mice Are a Novel Colitis Model in Which Innate Lymphoid Cell-derived IL-17 Is Involved in the Pathogenesis2014
- Author(s)
  Akitsu A, Kakuta S, Saijo S, Iwakura Y.
- Journal Title
  
  Exp. Anim.
  
  Volume: 63 Issue: 2 Pages: 235-246
- DOI
  10.1538/expanim.63.235
- NAID
  130003391627
- ISSN
  0007-5124, 1341-1357, 1881-7122
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24500488
[Journal Article] CTRP3 plays an important role in the development of collagen-induced arthritis in mice.2014
- Author(s)
  Murayama MA, Kakuta S, Maruhashi T, Shimizu K, Seno A, Kubo S, Sato N, Saijo S, Hattori M, Iwakura Y.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 443 Issue: 1 Pages: 42-48
- DOI
  10.1016/j.bbrc.2013.11.040
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390101, KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-24500488
[Journal Article] Gene Targeting Study Reveals Unexpected Expression of Brain expressed X-linked 2 in Endocrine and Tissue Stem/progenitor Cells in Mice2014
- Author(s)
  Keiichi Ito, Satoshi Yamazaki, Ryo Yamamoto, Yoko Tajima, Ayaka Yanagida, Toshihiro Kobayashi, Megumi Kato-Itoh, Shigeru Kakuta, Yoichiro Iwakura, Hiromitsu Nakauchi, Akihide Kamiya,
- Journal Title
  
  J Biol Chem
  
  Volume: 289(43) Issue: 43 Pages: 29892-911
- DOI
  10.1074/jbc.m114.580084
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-13J05787, KAKENHI-PLANNED-23106004, KAKENHI-PROJECT-24249056, KAKENHI-PROJECT-24500488, KAKENHI-PROJECT-25640044, KAKENHI-PROJECT-25713037
[Journal Article] Stage-specific roles for Cxcr4 signaling in murine hematopoietic stem/progenitor cells in the process of bone marrow repopulation.2014
- Author(s)
  Lai CY, Yamazaki S, Okabe M, Suzuki S, Maeyama Y, Iimura Y, Onodera M, Kakuta S, Iwakura Y, Nojima M, Otsu M, Nakauchi H.
- Journal Title
  
  Stem Cells.
  
  Volume: - Issue: 7 Pages: 1929-42
- DOI
  10.1002/stem.1670
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23106004, KAKENHI-PROJECT-24249056, KAKENHI-PROJECT-24500488, KAKENHI-PROJECT-24659127
[Journal Article] Generation of a mouse model with down-regulated U50 snoRNA (SNORD50) expression and its organ-specific phenotypic modulation2013
- Author(s)
  Soeno Y, Fujita K, Kudo T, Asagiri M, Kakuta S, Taya Y, Shimazu Y, Sato K, Tanaka-Fujita R, Kubo S, Iwakura Y, Nakamura Y, Mori S, and Aoba T
- Journal Title
  
  PLoS ONE
  
  Volume: 8 Issue: 8 Pages: e72105-e72105
- DOI
  10.1371/journal.pone.0072105
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592716, KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-24500488, KAKENHI-PROJECT-24592780, KAKENHI-PROJECT-24659822, KAKENHI-PROJECT-24689056, KAKENHI-PROJECT-25462935, KAKENHI-PROJECT-25463154
[Journal Article] 遺伝子機能解析ツールとしてのノックアウトマウスの作出とバイオリソース2013
- Author(s)
  角田茂
- Journal Title
  
  信州医学雑誌
  
  Volume: 61(1) Pages: 3-13
- NAID
  130004551875
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24500488
[Journal Article] 遺伝子機能解析ツールとしてのノックアウトマウスの作出とバイオリソース2013
- Author(s)
  角田茂
- Journal Title
  
  信州医学雑誌
  
  Volume: 61(1) Pages: 3-11
- NAID
  130004551875
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23114504
[Journal Article] IL-1関連遺伝子ノックアウトマウスライブラリ作製の話2012
- Author(s)
  角田茂
- Journal Title
  
  細胞工学
  
  Volume: 31(7) Pages: 779-781
- Data Source
  KAKENHI-PUBLICLY-23114504
[Journal Article] ノックアウトマウス作製技術の進歩と網羅的作製プロジェクト2012
- Author(s)
  角田茂
- Journal Title
  
  生物工学会誌
  
  Volume: 90(9) Pages: 547-549
- NAID
  110009517325
- Data Source
  KAKENHI-PUBLICLY-23114504
[Journal Article] 真菌免疫応答におけるC型レクチン受容体の役割2012
- Author(s)
  角田茂, 西城忍
- Journal Title
  
  化学療法の領域
  
  Volume: 28 Pages: 59-66
- URL
  https://www.iyaku-j.com/iyakuj/system/M2-1/summary_viewer.php?trgid=24220
- Data Source
  KAKENHI-PROJECT-22700448
[Journal Article] IL-1関連遺伝子ノックアウトマウスライブラリ作製の話2012
- Author(s)
  角田茂
- Journal Title
  
  細胞工学
  
  Volume: 31(7) Pages: 779-781
- Data Source
  KAKENHI-PROJECT-24500488
[Journal Article] 真菌免疫応答におけるC型レクチン受容体の役割2012
- Author(s)
  角田茂
- Journal Title
  
  化学療法の領域
  
  Volume: 28 Pages: 59-66
- Data Source
  KAKENHI-PUBLICLY-23114504
[Journal Article] Up-regulation of polymeric immunoglobulin receptor expression by the heat-inactivated potential probiotic Bifidobacterium bifidum OLB6378 in a mouse intestinal explant model2012
- Author(s)
  Y.Nakamura
- Journal Title
  
  Scand J Immunol
  
  Volume: 72 Issue: 2 Pages: 176-183
- DOI
  10.1111/j.1365-3083.2011.02645.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009, KAKENHI-PROJECT-21380077, KAKENHI-PROJECT-22700448, KAKENHI-PUBLICLY-23114504
[Journal Article] ノックアウトマウス作製技術の進歩と網羅的作製プロジェクト2012
- Author(s)
  角田茂、岩倉洋一郎
- Journal Title
  
  生物工学会誌
  
  Volume: 90(9) Pages: 547-549
- NAID
  110009517325
- Data Source
  KAKENHI-PROJECT-24500488
[Journal Article] Kjellmaniella crassifolia Miyabe (Gagome) Extract Modulates Intestinal and Systemic Immune Responses2011
- Author(s)
  H.Yan
- Journal Title
  
  Bioscience, Biotechnology, and Biochemistry
  
  Volume: 75 Issue: 11 Pages: 2178-2183
- DOI
  10.1271/bbb.110473
- NAID
  10030396791
- ISSN
  0916-8451, 1347-6947
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009, KAKENHI-PROJECT-22700448, KAKENHI-PUBLICLY-23114504
[Journal Article] NYAP : a phosphoprotein family that links PI3K to WAVE1 signalling in neurons2011
- Author(s)
  K.Yokoyama
- Journal Title
  
  EMBO J
  
  Volume: 30 Issue: 23 Pages: 4739-4754
- DOI
  10.1038/emboj.2011.348
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009, KAKENHI-PLANNED-21115006, KAKENHI-PROJECT-21229006, KAKENHI-PROJECT-21680033, KAKENHI-PROJECT-22700391, KAKENHI-PROJECT-22700448, KAKENHI-PUBLICLY-23114504
[Journal Article] IL-12011
- Author(s)
  角田茂、岩倉洋一郎
- Journal Title
  
  モデル動物利用マニュアル
  
  Volume: (印刷中)
- Data Source
  KAKENHI-PROJECT-22700448
[Journal Article] アグリゲーション法によるキメラマウスの作製2010
- Author(s)
  角田茂、佐藤希、久保幸子、岩倉洋一郎
- Journal Title
  
  新遺伝子工学ハンドブック(松村正實、山本雅、岡崎康司編)
  
  Volume: 改訂第5版 Pages: 289-296
- Data Source
  KAKENHI-PROJECT-22700448
[Journal Article] Genetic background and gender effects on gross phenotypes in congenic lines of ALS2/alsin-deficient mice2010
- Author(s)
  Hadano S, Yoshii Y, Otomo A, Kunita R, Suzuki-Utsunomiya K, Pan L, Kakuta S, Iwasaki Y, Iwakura Y, and Ikeda JE
- Journal Title
  
  Neurosci Res.
  
  Volume: 68 Issue: 2 Pages: 131-136
- DOI
  10.1016/j.neures.2010.06.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22700448
[Journal Article] Dectin-2 recognition ofα-mannans and induction of Th17 differentiation is essential for host defense against Candida albicans2010
- Author(s)
  Saijo, S., Ikeda, S., Yamabe, K., Kakuta, S., Ishigame, H., Akitsu, A., Fujikado, N., Kusaka, T., Kubo, S., Chung, S., Komatsu, R., Miura, N., Adachi, Y., Ohno, N., Shibuya, K., Yamamoto, N., Kawakami, K., Yamasaki, S., Saito, T., Akira, S., and Iwakura,
- Journal Title
  
  Immunity
  
  Volume: 32 Pages: 681-691
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] コンディショナルターゲティング法2010
- Author(s)
  角田茂、岩倉洋一郎
- Journal Title
  
  新遺伝子工学ハンドブック(松村正實、山本雅、岡崎康司編)
  
  Volume: 改訂第5版 Pages: 297-302
- Data Source
  KAKENHI-PROJECT-22700448
[Journal Article] TNF, but not IL-6 and IL-17, is crucial for the development of T cell-independent psoriasis-like dermatitis in Il1rn^<-/-> mice2010
- Author(s)
  Nakajima, A., Matsuki, T., Komine, M., Asahina, A., Horai, R., Nakae, S., Ishigame, H., Kakuta, S., Saijo, S., and Iwakura, Y.
- Journal Title
  
  J. Immunol.
  
  Volume: 185 Pages: 1887-1893
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] TNF, but Not IL-6 and IL-17, Is Crucial for the Development of T Cell-Independent Psoriasis-Like Dermatitis in Il1rn-/-Mice2010
- Author(s)
  Nakajima A, Matsuki T, Komine M, Asahina A, Horai R, Nakae S, Ishigame H, Kakuta S, Saijo S, and Iwakura Y
- Journal Title
  
  J Immunol
  
  Volume: 185 Issue: 3 Pages: 1887-1893
- DOI
  10.4049/jimmunol.1001227
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22700448, KAKENHI-PROJECT-21390303
[Journal Article] Dectin-2 recognition of α-mannans and induction of Th17 differentiation is essential for host defense against Candida albicans.2010
- Author(s)
  Saijo, S., Ikeda, S., Yamabe, K., Kakuta, S., Ishigame, H., Akitsu, A., Fujikado, N., Kusaka, T., Kubo, S., Chung, S., Komatsu, R., Miura, N., Adachi, Y., Ohno, N., Shibuya, K., Yamamoto, N., Kawakami, K., Yamasaki, S., Saito, T., Akira, S., Iwakura, Y.
- Journal Title
  
  Immunity 32
  
  Pages: 1-11
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] Differential roles of IL-17A and IL-17F in host defense against mucoepithelial bacterial infection and allergic responses2009
- Author(s)
  Ishigame, H., Kakuta, S., Nagai, T., Nambu, A., Komiyama, Y., Kadoki, M., Tanahashi, Y., Akitsu, A., Kotaki, H., Sudo, K., Nakae, S., Sasakawa, C., and Iwakura, Y
- Journal Title
  
  Immunity
  
  Volume: 30 Pages: 108-119
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] Differential roles of IL-17A and IL-17F in host defense against mucoepithelial bacterial infection and allergic responses.2009
- Author(s)
  Ishigame, H., Kakuta, S., Nagai, T., Nambu, A., Komiyama, Y., Kadoki, M., Tanahashi, Y., Akitsu, A., Kotaki, H., Sudo, K., Nakae, S., Sasakawa, C., Iwakura, Y.
- Journal Title
  
  Immunity 30
  
  Pages: 108-119
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] 自然免疫認識受容体遺伝子欠損マウスの作製と解析2008
- Author(s)
  角田茂
- Journal Title
  
  食品と科学別冊2008
  
  Pages: 73-76
- Data Source
  KAKENHI-PROJECT-18700394
[Journal Article] Knockout mice lacking cPGES/p23, a constitutively expressed PGE(2) synthetic enzyme, are peri-natally lethal.2007
- Author(s)
  Nakatani, Y., Hokonohara, Y., Kakuta, S., Sudo, K., Iwakura, Y., Kudo, I.
- Journal Title
  
  Biochem. Biophys. Res. Commun. 362
  
  Pages: 387-92
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] Melanocortin receptor 2 is required for adrenal gland development, steroidogenesis and neonatal gluconeogenesis.2007
- Author(s)
  Chida, D., Nakagawa, S., Nagai, S., Sagara, H., Katsumata, H., Imaki, T., Suzuki, H., Mitani, F., Ogishima, T., Shimizu, C., Kotaki, H., Kakuta, S., Sudo, K., Koike, T., Kubo, M., Iwakura, Y.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA 104
  
  Pages: 18205-18210
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] インターフェロンによる抗ウイルス機構-2-5Aシステム2007
- Author(s)
  角田茂
- Journal Title
  
  炎症と免疫 15(2)
- Data Source
  KAKENHI-PROJECT-18700394
[Journal Article] Involvement of protein-tyrosine phosphatase PTPMEG in motor learning and cerebellar long-term depression.2007
- Author(s)
  Kina, S., Tezuka, T., Kusakawa, S., Kishimoto, Y., Kakizawa, S., Hashimoto, K., Ohsugi, M., Kiyama, Y., Horai, R., Sudo, K., Kakuta, S., Iwakura, Y., Iino, M., Kano, M., Manabe, T., Yamamoto, T.
- Journal Title
  
  Eur. J. Neurosci. 26
  
  Pages: 2269-2278
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] 用語解説IL-232007
- Author(s)
  角田茂
- Journal Title
  
  分子細胞治療 6
  
  Pages: 382-383
- Data Source
  KAKENHI-PROJECT-18700394
[Journal Article] 自然免疫認識受容体遺伝子欠損マウスの作製と解析2007
- Author(s)
  角田茂
- Journal Title
  
  食品と科学 (印刷中)
- Data Source
  KAKENHI-PROJECT-18700394
[Journal Article] 2',5'-オリゴアデニル酸合成酵素機能の研究の現状2007
- Author(s)
  角田茂
- Journal Title
  
  JSICR Newsletter 23
  
  Pages: 10-11
- Data Source
  KAKENHI-PROJECT-18700394
[Journal Article] The role of TNF a and IL-17 in the development of excess IL-1 signaling-induced inflammatory diseases in IL-1 receptor antagonist-deficient mice.2006
- Author(s)
  Ishigame, H., Nakajima, A., Saijo S., Komiyama, Y., Nambu, A., Matsuki, T., Nakae, S., Horai, R., Kakuta, S., Iwakura.Y
- Journal Title
  
  Ernst Schering Res Found Workshop. 56
  
  Pages: 129-153
- Data Source
  KAKENHI-PROJECT-17390140
[Journal Article] サイトカインと自己免疫疾患2006
- Author(s)
  角田茂
- Journal Title
  
  EXPERT 膠原病・リウマチ改訂第2版
  
  Pages: 42-47
- Data Source
  KAKENHI-PROJECT-17047011
[Journal Article] サイトカインと自己免疫疾患2006
- Author(s)
  角田茂
- Journal Title
  
  EXPERT 膠原病・リウマチ改訂第2版
  
  Pages: 42-7
- Data Source
  KAKENHI-PROJECT-17390140
[Journal Article] 発生工学技術による動物個体での遺伝子改変と医科学研究2006
- Author(s)
  角田茂
- Journal Title
  
  遺伝子工学集中マスター
  
  Pages: 74-83
- Data Source
  KAKENHI-PROJECT-18700394
[Journal Article] The role of TNF a and IL-17 in the development of excess IL-1 signaling-induced inflammatory diseases in IL-1 receptor antagonist-deficient mice.2006
- Author(s)
  Ishigame, H., Nakajima, A., Saijo S., Komiyama, Y., Nambu, A., Matsuki, T., Nakae, S., Horai, R., Kakuta, S., Iwakura, Y
- Journal Title
  
  Ernst Schering Res Found Workshop. 56
  
  Pages: 129-153
- Data Source
  KAKENHI-PROJECT-17047011
[Journal Article] サイトカインと自己免疫疾患2006
- Author(s)
  角田茂
- Journal Title
  
  EXPERT 膠原病・リウマチ改訂第2版
  
  Pages: 42-47
- Data Source
  KAKENHI-PROJECT-18700394
[Journal Article] サイトカインネットワークの異常による自己免疫疾患2005
- Author(s)
  角田茂ほか
- Journal Title
  
  最新医学 60
  
  Pages: 57-64
- Data Source
  KAKENHI-PROJECT-16700346
[Journal Article] IL-252005
- Author(s)
  角田茂ほか
- Journal Title
  
  サイトカイン・増殖因子用語ライブラリー
  
  Pages: 54-56
- Data Source
  KAKENHI-PROJECT-16700346
[Journal Article] IL-252005
- Author(s)
  角田茂
- Journal Title
  
  サイトカイン・増殖因子用語ライブラリー
  
  Pages: 54-55
- Data Source
  KAKENHI-PROJECT-16700346
[Journal Article] サイトカイン遺伝子改変マウス2004
- Author(s)
  角田茂
- Journal Title
  
  サイトカイン -state of arts
  
  Pages: 325-328
- Data Source
  KAKENHI-PROJECT-16700346
[Journal Article] 発生工学による関節炎モデル2004
- Author(s)
  角田茂
- Journal Title
  
  分子リウマチ 1(4)
  
  Pages: 269-275
- Data Source
  KAKENHI-PROJECT-16700346
[Journal Article] トランスジェニックマウスとノックアウトマウスの作製法の最近の進歩2003
- Author(s)
  角田茂
- Journal Title
  
  生物工学会誌 81
  
  Pages: 345-357
- Data Source
  KAKENHI-PROJECT-15039206
[Journal Article] TNF, but not IL-6 and IL-17, is crucial for the development of T cell-independent psoriasis-like dermatitis in Il1rn-/- mice.
- Author(s)
  Nakajima, A., Matsuki, T., Komine, M., Asahina, A., Horai, R., Ishigame, H., Nakae, S., Kakuta, S., Saijo, S., Iwakura, Y.
- Journal Title
  
  J. Immunol. (in press)
- Data Source
  KAKENHI-PROJECT-19059006
[Patent] 腸疾患の治療方法および治療用医薬組成物2011
- Inventor(s)
  岩倉洋一郎、角田茂、鈴木俊佐
- Industrial Property Rights Holder
  東京大学
- Filing Date
  2011-02-02
- Overseas
- Data Source
  KAKENHI-PROJECT-20220009
[Patent] IL-17A/IL-17Fを介した大腸がん発症抑制2010
- Inventor(s)
  岩倉洋一郎、角田茂、鈴木俊佐
- Industrial Property Rights Holder
  国立大学法人東京大学
- Filing Date
  2010-02-03
- Acquisition Date
  2010-02-03
- Data Source
  KAKENHI-PROJECT-19059006
[Patent] IL-17A/IL-17Fを介した大腸がん発症制御2010
- Inventor(s)
  岩倉洋一郎、角田茂、鈴木俊佐
- Industrial Property Rights Holder
  東京大学
- Filing Date
  2010-02-03
- Overseas
- Data Source
  KAKENHI-PROJECT-20015015
[Patent] IL-17A/IL-17Fを介した大腸がん発症抑制2010
- Inventor(s)
  岩倉洋一郎、角田茂、鈴木俊佐
- Industrial Property Rights Holder
  東京大学
- Filing Date
  2010-02-03
- Overseas
- Data Source
  KAKENHI-PROJECT-20220009
[Patent] IL-1タイプIIレセプター遺伝子の欠損変異体マウス2009
- Inventor(s)
  岩倉洋一郎、角田茂, 他4名
- Industrial Property Rights Holder
  国立大学法人,東京大学, 他10名
- Acquisition Date
  2009-08-20
- Data Source
  KAKENHI-PROJECT-20220009
[Patent] IL-17A/IL-17F制御による感染症治療・予防薬Differential Roles of Interleukin-17A and Interleukin-17F in Host Defense against Mucoepithelial Bacterial Infection and Allergic Responses2009
- Inventor(s)
  岩倉洋一郎、角田茂、石亀晴道
- Industrial Property Rights Holder
  国立大学法人東京大学
- Filing Date
  2009-12-28
- Acquisition Date
  2009-12-28
- Data Source
  KAKENHI-PROJECT-19059006
[Patent] IL-17A/IL-17F制御による感染症治療・予防薬、Differentail Roles of Interleukin-17A and Interleukin-17F in Host defense against Mucoepithelial Bacterial Infection and Allegic Responses2009
- Inventor(s)
  岩倉洋一郎、角田茂、石亀晴道
- Industrial Property Rights Holder
  東京大学
- Filing Date
  2009-12-28
- Overseas
- Data Source
  KAKENHI-PROJECT-20220009
[Patent] IL-1タイプIIレセプター遺伝子の欠損変異体マウス2009
- Inventor(s)
  岩倉洋一郎、角田茂、棚橋侑子、宝来玲子、畦地里衣、中嶋明子
- Industrial Property Rights Holder
  国立大学法人東京大学
- Filing Date
  2009-02-05
- Acquisition Date
  2009-02-05
- Data Source
  KAKENHI-PROJECT-19059006
[Patent] IL-17A/IL-17F制御によるアレルギーや細菌感染の治療法の開発Differential Roles of Interleukin-17A and Interleukin-17F in Host Defense against Mucoepithelial Bacterial Infection and Allergic Responses2008
- Inventor(s)
  岩倉洋一郎、角田茂、石亀晴道
- Industrial Property Rights Holder
  国立大学法人東京大学
- Filing Date
  2008-12-30
- Acquisition Date
  2008-12-30
- Data Source
  KAKENHI-PROJECT-19059006
[Presentation] 定着性向上型大腸菌のマウスへの投与による腸内細菌叢変化の解析2022
- Author(s)
  南篤、中島満幸、浅井健宏、水流功春、葛山智久、久和茂、角田茂、小川哲弘
- Organizer
  第35回日本微生物生態学会大会
- Data Source
  KAKENHI-PROJECT-21K18229
[Presentation] 抗生物質による固相面に高い付着性を示す大腸菌変異株のマウス腸管内定着性コントロール2022
- Author(s)
  中島満幸、浅井健宏、南篤、水流功春、田川陽一、葛山智久、久和茂、小川哲弘、角田茂
- Organizer
  第69回日本実験動物学会総会
- Data Source
  KAKENHI-PROJECT-21K18229
[Presentation] Disease models and species differences between mice and humans2022
- Author(s)
  Shigeru Kakuta
- Organizer
  Tri-Lab Joint Symposium 2022
- Data Source
  KAKENHI-PROJECT-21K18229
[Presentation] i-GONAD法を用いた様々な系統における遺伝子改変マウスの作出の試み2021
- Author(s)
  関口茉莉恵、角田茂、山藤あかり、真方文絵、松田二子、田中麗華、福井竜太郎、三宅健介、大塚正人、久和茂
- Organizer
  第164回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-18K19265
[Presentation] i-GONAD法を用いた簡便なゲノム改変マウスの作出の試み2021
- Author(s)
  関口茉莉恵、角田茂、山藤あかり、浅井健宏、小川哲弘、大塚正人、久和茂
- Organizer
  第68回日本実験動物学会総会
- Data Source
  KAKENHI-PROJECT-18K19265
[Presentation] Study on the mechanism and its application of biofilm formation regulated by the conserved ribonuclease, RNase T2, in Escherichia coli.2020
- Author(s)
  Atsushi Minami, Makoto Hidaka, Tomohisa Kuzuyama, Yoh-ichi Tagawa, Shigeru Kakuta, Tetsuhiro Ogawa
- Organizer
  第５回デザイン生命工学研究会
- Data Source
  KAKENHI-PROJECT-18K19265
[Presentation] 生物に普遍的に存在する分泌型リボヌクレアーゼ遺伝子欠損マウスの表現型解析2019
- Author(s)
  王辰、角田茂、小川哲弘、岩本京夏、餅井眞太郎、Mark Joseph M. Desamero、藤井渉、チェンバーズジェームズ、内田萌菜、村山正承、小川修平、米澤智洋、中山裕之、岩倉洋一郎、久和茂
- Organizer
  第84回日本インターフェロン・サイトカイン学会学術集会
- Data Source
  KAKENHI-PROJECT-18K19265
[Presentation] Generation of gene-modified mice and rats by i-GONAD method.2019
- Author(s)
  Akari Sando, Shigeru Kakuta, Takashi Matsuwaki, Yu Wei Chang, Tetsuhiro Ogawa, Masato Ohtsuka, Shigeru Kyuwa
- Organizer
  1st ToBeST symposium, Seoul
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03931
[Presentation] 普遍的リボヌクレアーゼのin vivo機能解析2019
- Author(s)
  角田茂、小川哲弘、藤井渉、チェンバーズジェームズ、王辰、餅井眞太郎、Mark Joseph Desamero、岩本京夏、内田萌菜、村山正承、小川修平、米澤智洋、中山裕之、岩倉洋一郎、久和茂
- Organizer
  第9回オルソオルガノジェネシス検討会
- Data Source
  KAKENHI-PROJECT-18K19265
[Presentation] 分泌型非特異的RNA分解酵素によるマウスコロナウイルス増殖抑制作用の解析2019
- Author(s)
  餅井眞太郎、小川哲弘、藤井渉、角田茂、久和茂
- Organizer
  第162回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-18K19265
[Presentation] i-GONAD法を用いた簡便な遺伝子欠損マウスおよびラット作出の試み2019
- Author(s)
  山藤あかり、角田茂、松脇貴志、大塚正人、久和茂
- Organizer
  第162回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-17H03931
[Presentation] 普遍的分泌型非特異的リボヌクレアーゼ遺伝子欠損マウスが呈する免疫異常の解析2018
- Author(s)
  角田茂、小川哲弘、藤井渉、チェンバーズジェームズ、岩本京夏、Desamero Mark Joseph M.、内田萌菜、秋津葵、村山正承、小川修平、米澤智洋、中山裕之、岩倉洋一郎、久和茂
- Organizer
  第56回日本実験動物学会総会
- Data Source
  KAKENHI-PROJECT-18K19265
[Presentation] The role of the IL-1 receptor in the centrally-elicited sickness response to lipopolysaccharide2017
- Author(s)
  Matsuwaki T, Shionoya K, Ihnatko R, Eskilsson A, Kakuta S, Dufour S, Schwaninger M, Waisman A, Muller W, Pinteaux E, Engblom D, Blomqvist A.
- Organizer
  International Cytokine & Interferon Society 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03931
[Presentation] Generation of genetically-modified mice as human disease models / analytical tools using CRISPR/Cas methods2015
- Author(s)
  角田　茂
- Organizer
  2015 Symposium on Future of Immunology, Development, and Life Science
- Place of Presentation
  ホテルリステル猪苗代（福島県耶麻郡猪苗代町）
- Year and Date
  2015-11-06
- Invited
- Data Source
  KAKENHI-PROJECT-25670191
[Presentation] 疾患モデル動物作製における発生工学の進歩とDOHaD研究への応用の可能性2014
- Author(s)
  角田茂
- Organizer
  第7回DOHaD寺子屋
- Place of Presentation
  早稲田大学理工学部（東京）
- Year and Date
  2014-12-20
- Invited
- Data Source
  KAKENHI-PROJECT-24500488
[Presentation] 遺伝子欠損マウスを用いたインターロイキン-1の負の調節因子の機能解析2014
- Author(s)
  五十嵐哲郎、清水謙次、秋津葵、久保幸子、劉陽、中嶋明子、宝来玲子、石亀晴道、松本清司、岩倉洋一郎、久和茂、角田茂
- Organizer
  第14回東京大学生命科学シンポジウム
- Place of Presentation
  伊藤国際学術研究センター（東京）
- Year and Date
  2014-04-26
- Data Source
  KAKENHI-PROJECT-24500488
[Presentation] IL-1の負の調節機構の解析とゲノム編集技術による標的遺伝子改変マウス作出の現状2014
- Author(s)
  角田茂
- Organizer
  東海医学会講演会
- Place of Presentation
  東海大学医学部（神奈川県伊勢原市）
- Year and Date
  2014-11-14
- Invited
- Data Source
  KAKENHI-PROJECT-25670191
[Presentation] 遺伝子改変マウスの作製・バイオリソース化とサイトカインの機能解析2014
- Author(s)
  角田茂
- Organizer
  平成26年度優駿会
- Place of Presentation
  東京大学農学部FS棟中島董一郎記念ホール（東京都文京区）
- Year and Date
  2014-11-22
- Invited
- Data Source
  KAKENHI-PROJECT-25670191
[Presentation] IL-1の負の調節機構の解析とゲノム編集技術による標的遺伝子改変マウス作出の現状2014
- Author(s)
  角田茂
- Organizer
  東海医学会講演会
- Place of Presentation
  東海大学医学部（伊勢原）
- Year and Date
  2014-11-14
- Invited
- Data Source
  KAKENHI-PROJECT-24500488
[Presentation] 遺伝子改変マウスの作製・バイオリソース化とサイトカインの機能解析2014
- Author(s)
  角田茂
- Organizer
  平成26年度優駿会
- Place of Presentation
  東京大学農学部フードサイエンス棟中島董一郎記念ホール（東京）
- Year and Date
  2014-11-22
- Invited
- Data Source
  KAKENHI-PROJECT-24500488
[Presentation] CRISPR/Cas9法による遺伝子改変マウスの作製と今後の展開2014
- Author(s)
  角田茂
- Organizer
  平成26年度免疫研究シンポジウム
- Place of Presentation
  水上ホテル聚楽（群馬県利根郡みなかみ町）
- Year and Date
  2014-11-07
- Invited
- Data Source
  KAKENHI-PROJECT-25670191
[Presentation] 疾患モデルマウスを用いたIL1/IL17ファミリー遺伝子の腸管ポリープ形成における役割2013
- Author(s)
  角田茂、鈴木俊佐、佐々木大和、五十嵐哲郎、渋川茉莉、村山正承、秋津葵、岡江寛明、石亀晴道、松本清司、久和茂、岩倉洋一郎
- Organizer
  第156回日本獣医学会学術集会
- Place of Presentation
  岐阜大学（岐阜）
- Data Source
  KAKENHI-PROJECT-24500488
[Presentation] 遺伝子欠損マウスを用いたIL-1の負の調節因子群の機能解析2013
- Author(s)
  五十嵐哲郎、清水謙次、秋津葵、久保幸子、劉陽、中嶋明子、宝来玲子、石亀晴道、松本清司、久和茂、岩倉洋一郎、角田茂
- Organizer
  第156回日本獣医学会学術集会
- Place of Presentation
  岐阜大学（岐阜）
- Data Source
  KAKENHI-PROJECT-24500488
[Presentation] ゲノム編集ツールによる新しい発生工学技術と疾患モデル研究の今後の展開2013
- Author(s)
  角田茂
- Organizer
  平成25年度免疫研究シンポジウム
- Place of Presentation
  ホテルリステル猪苗代（福島）
- Invited
- Data Source
  KAKENHI-PROJECT-24500488
[Presentation] IL-17-producing gamma-delta T cells are crucial for the development of autoimmune arthritis in IL-1 receptor antagonist-deficient mice.2013
- Author(s)
  Aoi Akitsu, Harumichi Ishigame, Shigeru Kakuta, Shinobu Saijo, Yoichiro Iwakura
- Organizer
  15th International Congress of Immunology
- Place of Presentation
  Milan (Italy)
- Data Source
  KAKENHI-PROJECT-24500488
[Presentation] インターロイキン-1受容体2型欠損マウスにおけるコラーゲン誘導関節炎の増悪化2013
- Author(s)
  清水謙次、角田茂、溝呂木暁彦、宝来玲子、中嶋明子、岩倉洋一郎
- Organizer
  第60回日本実験動物学会総会
- Place of Presentation
  つくば国際会議場エポカルつくば（茨城）
- Data Source
  KAKENHI-PROJECT-24500488
[Presentation] 遺伝子欠損マウスを用いた炎症性サイトカインの機能解析2013
- Author(s)
  角田茂
- Organizer
  平成25年度農学生命科学研究科研究交流会
- Place of Presentation
  弥生講堂（東京）
- Data Source
  KAKENHI-PROJECT-24500488
[Presentation] 疾患モデルマウスを用いた腸管ポリープ形成におけるIL-17ファミリーの役割2012
- Author(s)
  角田茂
- Organizer
  日本実験動物科学・技術九州2012（第59回日本実験動物学会総会、第46回日本実験動物技術者協会総会）
- Place of Presentation
  別府国際コンベンションセンター（大分県）
- Year and Date
  2012-05-24
- Data Source
  KAKENHI-PUBLICLY-23114504
[Presentation] 腸管ポリープ形成におけるIL-17ファミリーの役割の解析2012
- Author(s)
  角田茂
- Organizer
  平成23年度「個体レベルでのがん研究支援活動」班ワークショップ
- Place of Presentation
  大津
- Data Source
  KAKENHI-PUBLICLY-23114504
[Presentation] 疾患モデルマウスを用いた腸管ポリープ形成におけるIL-17ファミリーの役割2012
- Author(s)
  角田茂ほか
- Organizer
  日本実験動物科学・技術九州2012（第59回日本実験動物学会総会）
- Place of Presentation
  別府国際コンベンションセンター（大分県）
- Data Source
  KAKENHI-PROJECT-24500488
[Presentation] 腸管ポリープ形成におけるIL-17ファミリーの役割の解析2012
- Author(s)
  角田茂
- Organizer
  平成23年度「個体レベルでのがん研究支援活動」班ワークショップ
- Place of Presentation
  大津
- Data Source
  KAKENHI-PROJECT-20220009
[Presentation] 遺伝子変異マウスを用いたIL-17A/Fの消化管における機能の解析2012
- Author(s)
  角田茂
- Organizer
  第21回内毒素・LPS研究会
- Place of Presentation
  東京大学医学部入院棟A（東京都）
- Year and Date
  2012-06-23
- Invited
- Data Source
  KAKENHI-PUBLICLY-23114504
[Presentation] 腸管ポリープ形成とIL1/IL17の役割2012
- Author(s)
  角田茂
- Organizer
  第7回遺伝子栄養学研究会
- Place of Presentation
  北広島クラッセホテル（北海道）
- Year and Date
  2012-08-10
- Data Source
  KAKENHI-PUBLICLY-23114504
[Presentation] 疾患モデルマウスとサイトカイン2012
- Author(s)
  角田茂
- Organizer
  平成24年度免疫研究シンポジウム「自己免疫・アレルギー・炎症性腸疾患の発症機構の解明と治療法の開発」
- Place of Presentation
  箱根ホテル小涌園（神奈川県）
- Data Source
  KAKENHI-PROJECT-24500488
[Presentation] 腸管ポリープ形成におけるIL-17ファミリーの役割の解析2012
- Author(s)
  角田茂
- Organizer
  平成23年度「個体レベルでのがん研究支援活動」班ワークショップ
- Place of Presentation
  大津
- Data Source
  KAKENHI-PROJECT-22700448
[Presentation] 疾患モデルマウスとサイトカイン2012
- Author(s)
  角田茂
- Organizer
  平成24年度免疫研究シンポジウム「自己免疫・アレルギー・炎症性腸疾患の発症機構の解明と治療法の開発」
- Place of Presentation
  箱根ホテル小涌園（神奈川県）
- Year and Date
  2012-11-16
- Data Source
  KAKENHI-PUBLICLY-23114504
[Presentation] 腸管ポリープ形成におけるIL-17ファミリーの役割2012
- Author(s)
  角田茂
- Organizer
  平成23年度「個体レベルでのがん研究支援活動」班ワークショップ
- Place of Presentation
  大津
- Data Source
  KAKENHI-PROJECT-22700448
[Presentation] ApcMinマウスの腸管ポリープ形成におけるIL-17AおよびIL-17Fの役割2011
- Author(s)
  Shigeru Kakuta
- Organizer
  第40回日本免疫学会総会・学術集会
- Place of Presentation
  幕張
- Data Source
  KAKENHI-PROJECT-22700448
[Presentation] Involvement of interleukin (IL)-17A and IL-17F in development of intestinal polyps in Apc^<Min> mice2011
- Author(s)
  Shigeru Kakuta
- Organizer
  第40回日本免疫学会総会・学術集会
- Place of Presentation
  幕張メッセ,千葉
- Data Source
  KAKENHI-PROJECT-20220009
[Presentation] 疾患モデルマウスを用いた腸管ポリープ形成におけるIL-17AおよびIL-17Fの役割の解析2011
- Author(s)
  角田茂
- Organizer
  第58回日本実験動物学会総会
- Place of Presentation
  江戸川
- Data Source
  KAKENHI-PUBLICLY-23114504
[Presentation] 遺伝子改変マウスを用いたIL-17A/Fの感染・炎症・発がんにおける役割の解析2011
- Author(s)
  角田茂
- Organizer
  第30回信州免疫アレルギー懇話会
- Place of Presentation
  松本
- Year and Date
  2011-12-21
- Data Source
  KAKENHI-PROJECT-20220009
[Presentation] 遺伝子改変マウスを取り巻く最近の動向と基礎医学研究への応用2011
- Author(s)
  角田茂
- Organizer
  信州実験動物研究会第76回勉強会
- Place of Presentation
  松本(招待講演)
- Year and Date
  2011-10-21
- Data Source
  KAKENHI-PUBLICLY-23114504
[Presentation] 遺伝子改変マウスを取り巻く最近の動向と基礎医学研究への応用2011
- Author(s)
  角田茂
- Organizer
  信州実験動物研究会第76回勉強会
- Place of Presentation
  松本
- Year and Date
  2011-10-21
- Data Source
  KAKENHI-PROJECT-20220009
[Presentation] 遺伝子改変マウスを用いたIL-17A/Fの感染・炎症・発がんにおける役割の解析2011
- Author(s)
  角田茂
- Organizer
  第30回信州免疫アレルギー懇話会
- Place of Presentation
  松本
- Year and Date
  2011-12-21
- Data Source
  KAKENHI-PROJECT-22700448
[Presentation] 遺伝子改変マウスを取り巻く最近の動向と基礎医学研究への応用2011
- Author(s)
  角田茂
- Organizer
  信州実験動物研究会第76回勉強会
- Place of Presentation
  松本
- Year and Date
  2011-02-21
- Data Source
  KAKENHI-PROJECT-22700448
[Presentation] 疾患モデルマウスを用いた腸管ポリープ形成におけるIL-17AおよびIL-17Fの役割の解析2011
- Author(s)
  角田茂
- Organizer
  第58回日本実験動物学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20220009
[Presentation] 遺伝子改変マウスを用いたIL-17A/Fの感染・炎症・発がんにおける役割の解析2011
- Author(s)
  角田茂
- Organizer
  第30回信州免疫アレルギー懇話会
- Place of Presentation
  松本
- Year and Date
  2011-12-21
- Data Source
  KAKENHI-PUBLICLY-23114504
[Presentation] 疾患モデルマウスを用いた腸管ポリープ形成におけるIL-17AおよびIL-17Fの役割の解析2011
- Author(s)
  角田茂
- Organizer
  第58回日本実験動物学会総会
- Place of Presentation
  江戸川
- Data Source
  KAKENHI-PROJECT-22700448
[Presentation] Apc^<Min>マウスの腸管ポリープ形成におけるIL-17AおよびIL-17Fの役割(Involvement of interleukin (IL)-17A and IL-17F in development of intestinal polyps in Apc^<Min> mice)2011
- Author(s)
  Shigeru Kakuta
- Organizer
  第40回日本免疫学会総会・学術集会
- Place of Presentation
  幕張
- Data Source
  KAKENHI-PUBLICLY-23114504
[Presentation] 遺伝子改変マウスを取り巻く最近の動向と基礎医学研究への応用2011
- Author(s)
  角田茂
- Organizer
  信州実験動物研究会第76回勉強会
- Place of Presentation
  松本(招待講演)
- Year and Date
  2011-10-21
- Data Source
  KAKENHI-PROJECT-22700448
[Presentation] Apc^<Min>マウスの腸管ポリープ形成におけるIL-17AおよびIL-17Fの役割(Involvement of interleukin (IL)-17A and IL-17F in development of intestinal polyps in Apc^<Min> mice)2011
- Author(s)
  Shigeru Kakuta
- Organizer
  第40回日本免疫学会総会・学術集会
- Place of Presentation
  幕張
- Data Source
  KAKENHI-PROJECT-22700448
[Presentation] The role of IL-1 and 17 family genes in development of intestinal polyps.2010
- Author(s)
  Shigeru Kakuta
- Organizer
  第33回日本分子生物学会年会第83回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートアイランド
- Data Source
  KAKENHI-PROJECT-20220009
[Presentation] Generation and analysis of oligoadenylate synthetase family genes-deficient mice.2010
- Author(s)
  Shigeru Kakuta
- Organizer
  14th International Congress of Immunology
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22700448
[Presentation] 腸管ポリープ形成におけるIL-17の役割の検討2010
- Author(s)
  角田茂
- Organizer
  第75回日本インターフェロン・サイトカイン学会学術集会
- Place of Presentation
  小倉北北九州国際会議場
- Data Source
  KAKENHI-PROJECT-20220009
[Presentation] Generation and analysis of oligoadenylate synthetase family genes-deficient mice2010
- Author(s)
  Shigeru Kakuta
- Organizer
  14th International Congress of Immunology
- Place of Presentation
  Kobe
- Data Source
  KAKENHI-PROJECT-22700448
[Presentation] 発生工学的アプローチによるIL-17ファミリーを中心としたサイトカインの機能解析2010
- Author(s)
  角田茂
- Organizer
  東海医学会講演会・例会
- Place of Presentation
  伊勢原東海大学
- Year and Date
  2010-07-13
- Data Source
  KAKENHI-PROJECT-20220009
[Presentation] The role of IL-1 and 17 family genes in development of intestinal polyps.2010
- Author(s)
  Shigeru Kakuta
- Organizer
  BMB2010(第33回日本分子生物学会年会第83回日本生化学会大会合同大会)
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22700448
[Presentation] IL-17A and IL-17F are important for the development of intestinal polyps in APC^<MIN> mice by accelerating blood vessel formation.2010
- Author(s)
  Shigeru Kakuta
- Organizer
  8th Joint Conference of the ICS and ISICR, Cytokines 2010
- Place of Presentation
  Chicago
- Data Source
  KAKENHI-PROJECT-22700448
[Presentation] 腸管ポリープ形成におけるIL-17の役割の検討2010
- Author(s)
  角田茂
- Organizer
  第75回日本インターフェロン・サイトカイン学会学術集会
- Place of Presentation
  小倉
- Data Source
  KAKENHI-PROJECT-22700448
[Presentation] インターロイキン-17の腸管ポリープ形成における役割の解析2010
- Author(s)
  角田茂
- Organizer
  第5回核酸・核タンパク機能性研究会学術集会
- Place of Presentation
  北海道恵庭リサーチビジネスパーク
- Year and Date
  2010-08-06
- Data Source
  KAKENHI-PROJECT-20220009
[Presentation] The role of IL-1 and 17 family genes in development of intestinal polyps2010
- Author(s)
  Shigeru Kakuta
- Organizer
  BMB2010(第33回日本分子生物学会年会第83回日本生化学会大会合同大会)
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22700448
[Presentation] 東京大学医科学研究所システム疾患モデル研究センターにおける遺伝子改変マウスの供給について2010
- Author(s)
  角田茂
- Organizer
  第57回日本実験動物学会総会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-22700448
[Presentation] 東京大学医科学研究所システム疾患モデル研究センターにおける遺伝子改変マウスの供給について2010
- Author(s)
  角田茂
- Organizer
  第57回日本実験動物学会
- Place of Presentation
  京都号テレサ
- Data Source
  KAKENHI-PROJECT-20220009
[Presentation] Generation and analysis of oligoadenylate synthetase family genes-deficient mice.2010
- Author(s)
  Shigeru Kakuta
- Organizer
  14^<th> interntional congress of immunology
- Place of Presentation
  Kobe神戸ポートピアホテル神戸国際展示場
- Data Source
  KAKENHI-PROJECT-20220009
[Presentation] 発生工学的アプローチによるIL-17ファミリーを中心としたサイトカインの機能解析2010
- Author(s)
  角田茂
- Organizer
  東海医学会講演会・例会
- Place of Presentation
  伊勢原
- Year and Date
  2010-07-13
- Data Source
  KAKENHI-PROJECT-22700448
[Presentation] IL-17A and IL-17F are important for the development of intestinal polyps in APC^<MIN> mice by accelerating blood vessel formation.2010
- Author(s)
  Shigeru Kakuta
- Organizer
  8th Joint Conference of the ICS and ISICR, Cytokines 2010
- Place of Presentation
  Chicago, USA
- Data Source
  KAKENHI-PROJECT-20220009
[Presentation] インターロイキン-17の腸管ポリープ形成における役割の解析2010
- Author(s)
  角田茂
- Organizer
  第5回核酸・核タンパク機能性研究会学術集会
- Place of Presentation
  恵庭
- Year and Date
  2010-08-06
- Data Source
  KAKENHI-PROJECT-22700448
[Presentation] IL-17A and IL-17F are important for the development of intestinal polyps in APCMIN mice by accelerating blood vessel formation2010
- Author(s)
  Shigeru Kakuta
- Organizer
  8th Joint Conference of the ICS and ISICR, Cytokines
- Place of Presentation
  Chicago
- Data Source
  KAKENHI-PROJECT-22700448
[Presentation] Adoptive and innate immunity related gene-deficient mice generated by IMSUT.2009
- Author(s)
  Kakuta S
- Organizer
  Manitoba Centre for Disease Modeling Symposium
- Place of Presentation
  Winnipeg, Canada
- Year and Date
  2009-10-19
- Data Source
  KAKENHI-PROJECT-20220009
[Presentation] Adoptive and innate immunity related gene-deficient mice generated by IMSUT2009
- Author(s)
  角田茂
- Organizer
  Manitoba Centre for Disease Modeling Symposium
- Place of Presentation
  Winnipeg(CAN)
- Year and Date
  2009-10-19
- Data Source
  KAKENHI-PROJECT-20015015
[Presentation] Generation and analysis of oligoadenylate synthetase family genes-deficient mice.2009
- Author(s)
  Kakuta S
- Organizer
  4th Asia Mutant Mouse Resource Association(AMMRA)meeting
- Place of Presentation
  Kumamoto
- Data Source
  KAKENHI-PROJECT-20220009
[Presentation] 発生工学的アプローチによるサイトカインの機能解明への取り組み2009
- Author(s)
  角田茂
- Organizer
  第18回AGH Seminar Consortium
- Place of Presentation
  帯広
- Year and Date
  2009-07-31
- Data Source
  KAKENHI-PROJECT-20015015
[Presentation] 自然免疫認識受容体遺伝子欠損マウスの作製と解析2007
- Author(s)
  角田茂
- Organizer
  第2回核酸・核タンパク機能性研究会学術集会
- Place of Presentation
  恵庭
- Year and Date
  2007-08-10
- Data Source
  KAKENHI-PROJECT-19059006
[Presentation] 自然免疫認識受容体遺伝子欠損マウスの作製と解析2007
- Author(s)
  角田茂
- Organizer
  第2回核酸・核タンパク機能性研究会学術集会
- Place of Presentation
  恵庭
- Year and Date
  2007-08-10
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390140
[Presentation] 遺伝子欠損マウスを用いた2',5'-オリゴアデニル酸合成酵素の機能解析2007
- Author(s)
  角田茂
- Organizer
  第72回日本インターフェロン・サイトカイン学会学術集会
- Place of Presentation
  京都
- Year and Date
  2007-07-05
- Data Source
  KAKENHI-PROJECT-18700394
[Presentation] 遺伝子欠損マウスを用いた2',5'-オリゴアデニル酸合成酵素の機能解析2007
- Author(s)
  角田茂
- Organizer
  BMB2007(第30回日本分子生物学会年会第80回日本生化学会大会合同大会)
- Place of Presentation
  横浜
- Year and Date
  2007-12-14
- Data Source
  KAKENHI-PROJECT-18700394
[Presentation] 炎症性サイトカインの腸管ポリープ形成における役割の検討2007
- Author(s)
  角田茂
- Organizer
  第54回日本実験動物学会総会
- Place of Presentation
  江戸川
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390140
[Presentation] 自然免疫認識受容体遺伝子欠損マウスの作製と解析2007
- Author(s)
  角田茂
- Organizer
  第2回核酸・核タンパク機能性研究会学術集会
- Place of Presentation
  恵庭
- Year and Date
  2007-08-10
- Data Source
  KAKENHI-PROJECT-18700394
[Presentation] 自然免疫認識受容体遺伝子欠損マウスの作製と解析2006
- Author(s)
  角田茂
- Organizer
  第1回核酸・核タンパク機能性研究会学術集会
- Place of Presentation
  恵庭
- Year and Date
  2006-08-10
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390140
[Presentation] 遺伝子改変マウス維持管理のためのコンピュータープログラム「動物系統管理システム」の構築と改良2006
- Author(s)
  角田茂
- Organizer
  第53回日本実験動物学会総会
- Place of Presentation
  神戸
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390140
[Presentation] 遺伝子変異マウスを用いたIL-17A/Fの消化管における機能の解析
- Author(s)
  角田茂ほか
- Organizer
  第21回内毒素・LPS研究会
- Place of Presentation
  東京大学医学部入院棟A（東京都）
- Invited
- Data Source
  KAKENHI-PROJECT-24500488
[Presentation] 新規IL-1シグナル過剰モデルマウスにおける炎症性疾患の発症について
- Author(s)
  五十嵐哲郎、清水謙次、秋津葵、久保幸子、劉陽、中嶋明子、宝来玲子、石亀晴道、松本清司、岩倉洋一郎、久和茂、角田茂
- Organizer
  第79回日本インターフェロン・サイトカイン学会学術集会
- Place of Presentation
  北海道大学医学部学友会館「ラフテ」（札幌）
- Year and Date
  2014-06-19 – 2014-06-20
- Data Source
  KAKENHI-PROJECT-24500488
[Presentation] 腸管ポリープ形成とIL1/IL17の役割
- Author(s)
  角田茂ほか
- Organizer
  第7回遺伝子栄養学研究会
- Place of Presentation
  北広島クラッセホテル（北海道）
- Data Source
  KAKENHI-PROJECT-24500488
[Presentation] 新規大腸炎モデルRag2<-/->Il1rn<-/->マウスはILC3細胞由来IL-17Aが病態形成に重要な役割を果たしている
- Author(s)
  秋津葵、角田茂、西城忍、岩倉洋一郎
- Organizer
  日本実験動物科学技術さっぽろ2014（第61回日本実験動物学会総会）
- Place of Presentation
  札幌コンベンションセンター（札幌）
- Year and Date
  2014-05-15 – 2014-05-17
- Data Source
  KAKENHI-PROJECT-24500488
[Presentation] ゲノム編集ツールによる新しい発生工学技術と疾患モデル研究の今後の展開
- Author(s)
  角田　茂
- Organizer
  平成25年度免疫研究シンポジウム
- Place of Presentation
  ホテルリステル猪苗代（福島県耶麻郡猪苗代町）
- Invited
- Data Source
  KAKENHI-PROJECT-25670191
[Presentation] Interleukin-1 receptor type 2 suppresses collagen-induced arthritis by inhibiting interleukin-1 signal on macrophages.
- Author(s)
  Kenji Shimizu, Akiko Nakajima, Katsuko Sudo, Yang Liu, Atsuhiko Mizoroki, Reiko Horai, Shigeru Kakuta, Yoichiro Iwakura.
- Organizer
  第43回日本免疫学会総会・学術集会
- Place of Presentation
  国立京都国際会館（京都）
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-24500488
[Presentation] 遺伝子改変マウスを用いた炎症性サイトカインの機能解析
- Author(s)
  角田　茂
- Organizer
  平成25年度農学生命科学研究科研究交流会
- Place of Presentation
  東京大学弥生講堂（東京都文京区）
- Data Source
  KAKENHI-PROJECT-25670191
[Presentation] CRISPR/Cas9法による遺伝子改変マウスの作製と今後の展開
- Author(s)
  角田茂
- Organizer
  平成26年度免疫研究シンポジウム
- Place of Presentation
  水上ホテル聚楽（みなかみ）
- Year and Date
  2014-11-07 – 2014-11-08
- Invited
- Data Source
  KAKENHI-PROJECT-24500488
[Presentation] 遺伝子欠損マウスを用いたIL-1Raの２つのアイソフォームの機能解析
- Author(s)
  五十嵐哲郎、清水謙次、秋津葵、久保幸子、劉陽、中嶋明子、宝来玲子、石亀晴道、松本清司、岩倉洋一郎、久和茂、角田茂
- Organizer
  第157回日本獣医学会学術集会
- Place of Presentation
  北海道大学高等教育推進機構（札幌）
- Year and Date
  2014-09-09 – 2014-09-12
- Data Source
  KAKENHI-PROJECT-24500488
[Presentation] IL-1の負の調節因子欠損マウスを用いた新規炎症性疾患モデルマウス作出の試み
- Author(s)
  五十嵐哲郎、清水謙次、秋津葵、久保幸子、劉陽、中嶋明子、宝来玲子、石亀晴道、松本清司、久和茂、岩倉洋一郎、角田茂
- Organizer
  日本実験動物科学技術さっぽろ2014（第61回日本実験動物学会総会）
- Place of Presentation
  札幌コンベンションセンター（札幌）
- Year and Date
  2014-05-15 – 2014-05-17
- Data Source
  KAKENHI-PROJECT-24500488
[Presentation] IL-1 receptor antagonist-deficient mice develop autoimmune arthritis due to an intrinsic defect in IL-17-producing gammadelta T cells.
- Author(s)
  Aoi Akitsu, Shigeru Kakuta, Shinobu Saijo, Yoichiro Iwaura.
- Organizer
  第43回日本免疫学会総会・学術集会
- Place of Presentation
  国立京都国際会館（京都）
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-24500488
[Presentation] Interleukin-1 receptor type 2 suppresses collagen-induced arthritis by inhibiting interleukin-1 signal on macrophages.
- Author(s)
  Shimizu K, Nakajima A, Sudo K, Yang L, Mizoroki A, Ikarashi T, Horai R, Kakuta S, Watanabe T, and Iwakura Y.
- Organizer
  Cytokines Down Under in 2014: From Bench to Beyond (ICIS 2014)
- Place of Presentation
  Melbourne
- Year and Date
  2014-10-26 – 2014-10-29
- Data Source
  KAKENHI-PROJECT-24500488

1. IWAKURA Yoichiro (10089120)

# of Collaborated Projects: 16 results

# of Collaborated Products: 15 results
2. SAIJO Shinobu (60396877)

# of Collaborated Projects: 8 results

# of Collaborated Products: 8 results
3. SUDO Katsuko (50126091)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
4. Ogawa Tetsuhiro (40323480)

# of Collaborated Projects: 4 results

# of Collaborated Products: 9 results
5. FUJIKADO Noriyuki (90447334)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
6. CE Tang (00572166)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. KUSAKA Toshimasa (60466836)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
8. HIGUCHI Keiichi (20173156)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. MORI Masayuki (60273190)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. SAWASHITA Jinko (40359732)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. KAMETANI Fuyuki (70186013)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. 保田尚孝 (90323641)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. 田川陽一 (70262079)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
14. KAIFU TomonoriI (90343037)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. MA GUANGYU (60572162)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
16. HIROSE Masamichi (40273081)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. MATSUMOTO Kiyoshi (40173893)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
18. NAGASE Hisashi (70303451)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. HORI Masatoshi (70211547)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. NAKAYAMA Jun (10221459)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. TAKAMOTO Masaya (90226928)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. KAWAKUBO Masatomo (70397305)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. Nishifuji Koji (20365422)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. Tsuji Noriko (30343990)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
25. OHTSUKA Masato (90372945)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. Matsuwaki Takashi (20447361)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
27. Yonezawa Tomohiro (10433715)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 宝来玲子 (20313091)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 井手香織 (40550281)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 平山和宏 (60208858)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
31. 中村伸吾 (00505323)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. 幸谷愛 (00517477)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. 小川智子 (90466011)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. 藤井渉 (40708161)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. 盆子原誠 (50343611)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
36. 前田真吾 (80755546)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
37. 林田直樹 (40420517)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
38. 後藤康之 (50553434)

# of Collaborated Projects: 1 results

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39. 足立はるよ (20595962)

# of Collaborated Projects: 1 results

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40. Chung Soo・hyun (40712443)

# of Collaborated Projects: 1 results

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41. 富安博隆 (70776111)

# of Collaborated Projects: 1 results

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42. 越野裕子 (80436518)

# of Collaborated Projects: 1 results

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43. 西山啓太 (40756029)

# of Collaborated Projects: 1 results

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44. 岩槻健 (50332375)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
45. MIURA Hiromi

# of Collaborated Projects: 1 results

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46. 小出雅則

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
47. 中司敦子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
48. 佐藤かおり

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
49. 青葉孝昭

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
50. 島津徳人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
51. 添野雄一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
52. 田谷雄二

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
53. 中内啓光

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kakuta Shigeru 角田 茂

KAKUTA Shigeru 角田 茂

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Development of novel technology for regulating biological functions via colonization-improved E. coli: in vivo trial using disease model animalPrincipal Investigator

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Generation and analysis of disease model mice with multiple phenotypes caused by disorder in RNA metabolism.Principal Investigator

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Kakuta Shigeru 角田茂

KAKUTA Shigeru 角田茂