OKUMURA Higeki 奥村茂樹

Researcher Number	80350825
Affiliation (based on the past Project Information) *help	2005: 松本歯大, 歯学部, 助手 2002 – 2004: School of Dentistry, Biochemistry, Research Assistant, 歯学部, 助手
Review Section/Research Field	Principal Investigator Functional basic dentistry Except Principal Investigator Functional basic dentistry / Functional basic dentistry / Orthodontic/Pediatric dentistry / Morphological basic dentistry
Keywords	Principal Investigator カルシトニン / 微小管 / アクチン / 破骨細胞 Except Principal Investigator 破骨細胞 / SOD / IL-1 / OPG / Porphyromanas gingivalis / MyD88 … More / 骨芽細胞 / 骨吸収 / Ca^<2+> / M-CSF / op / BMP / 骨形成 / IL-6 / TRAM / TRIF / LPS / Oxidoreductase / Metallo enzyme / Reactive oxygen / スーパーオキシドジスムターゼ / Porphyromonas gingivalis / 部位特異的変異 / 金属選択性 / 酸化還元酵素 / 金属酵素 / 活性酸素 / リポ多糖 / RANKL / オステオプロテゲリン / ビスフォスフォネート / EPR spectrum / site-directed mutagenesis / cambialistic enzyme / Lysosome / Vacuole / Transcytosis / Transportation in cell / Endocytosis / Bone matrix / Osteoclast / Ca^<+2> / lysosome / vacuole / transcytosis / 細胞内輸送 / endocytosis / 骨基質 / osteoporosis / coupling factor / bone resorption / bone formation / 共役機構 / 象牙芽細胞 / 骨粗鬆症 / カップリングファクター / 骨代謝共役因子 / Protocadherin / Type I Collagen / horse teeth / EDTA soluble fraction / Cementum / 免疫反応 / 二次元電気泳動 / EDTA抽出 / 特異的タンパク質 / EDTA可溶 / EDTA可溶画分 / セメント質 / ウマ歯冠 / プロトカドヘリン / I型コラーゲン / mouse / bone marrow macrophage / TLR4 / 自然免疫 / マウス / 骨髄マクロファージ / cambialistic / 歯周病原菌 / Toll-like receptor / Lipopeptide / Lipopolysaccharide / Osteoclasts / TNF / マクロファージ / アルカリフォスファターゼ / 骨誘導因子 / 骨代謝共役 / プロトンポンプ / 吸収窩 / アクチンリンング / 細胞骨格 / バフィロマイシン / 吸収窩形成 / 液胞型プロトンポンプ / アクチンリング / カルシトニン Less

破骨細胞によるビスフォスホネートの特異的取り込み機構の解析
- Principal Investigator
  
  MIYAZAWA Hiroo
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Orthodontic/Pediatric dentistry
- Research Institution
  Matsumoto Dental University
生きた破骨細胞のリアルタイム観察によるカルシトニン作用の解明Principal Investigator
- Principal Investigator
  
  奥村茂樹
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Matsumoto Dental University
Ca^<2+> kinetics in mature osteoclast
- Principal Investigator
  
  YAMAKI Mariko
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Matsumoto Dental University
A change of the metal-specific active site structure of superoxide dismutase from Porphyromonas gingivalis by the mutation of Gly155Thr.
- Principal Investigator
  
  HIRAOKA B.Yukihiro
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Matsumoto Dental University
Signal transduction of RANK and Toll-like receptor in alveolar bone destruction
- Principal Investigator
  
  UDAGAWA Nobuyuki
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Matsumoto Dental University
Determination of Cementum Specific Proteins in Horse Molar Teeth
- Principal Investigator
  
  FUKASAWA Kayoko
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Matsumoto Dental University
Analysis of tooth development of osteoprotegerin- deficient mice
- Principal Investigator
  
  NAKAMURA Hiroshi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthodontic/Pediatric dentistry
- Research Institution
  Matsumoto Dental University
In vitro evolution of SOD by DNA shufihing
- Principal Investigator
  
  HIRAOKA B.yukihiro
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Matsumoto Dental University
Analysis of signal transduction of osteoclast differentiation factor (RANKL) in alveolar bone destruction
- Principal Investigator
  
  UDAGAWA Nobuyuki
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Matsumoto Dental University

All 2006 2004

All Journal Article

[Journal Article] Coordination of microtubules and the actin cytoskeleton is important in osteoclast function, but Calcitonin disrupts sealing zones without affecting microtubules networks.2006
- Author(s)
  Okumura S.
- Journal Title
  
  Bone (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591847
[Journal Article] Induction of gicerin/CD146 in the rat carotid artery after balloon injury.2004
- Author(s)
  Okumura S et al.
- Journal Title
  
  Biochemical and Biophysical Research Communications 313
  
  Pages: 902-906
- Data Source
  KAKENHI-PROJECT-16791138
[Journal Article] 骨粗鬆症学-基礎・臨床研究の新しいパラダイム-概論:破骨細胞の分化・骨吸収調節機構2004
- Author(s)
  奥村茂樹他
- Journal Title
  
  日本臨床 62
  
  Pages: 90-96
- Data Source
  KAKENHI-PROJECT-16791138
[Journal Article] 液胞型プロトン-ATPaseとアクチンフィラメントの結合2004
- Author(s)
  奥村茂樹他
- Journal Title
  
  THE BONE 18
  
  Pages: 97-97
- Data Source
  KAKENHI-PROJECT-16791138

1. UDAGAWA Nobuyuki (70245801)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
2. MIZOGUCHI Toshihide (90329475)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. HIRAOKA Yukihiko (20097512)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
4. OZAWA Hidehiro (60018413)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
5. TAKAHASHI Naoyuki (90119222)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. MIYAZAWA Hiroo (90147637)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. FUKASAWA Kayoko (60064698)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. SAHARA Noriyuki (70064699)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. 中村美どり (90278177)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 中道裕子 (20350829)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. KOBAYASHI Yasuhiro (20264252)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. FURUSAWA Kiyofumi (90165481)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. NAKAMURA Hiroshi (00278178)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. YAMAKI Mariko (90360221)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. HOSOYA Akihiro (70350824)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. YAMASHITA Teruhito (90302893)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

OKUMURA Higeki 奥村 茂樹

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生きた破骨細胞のリアルタイム観察によるカルシトニン作用の解明Principal Investigator

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[Journal Article] Coordination of microtubules and the actin cytoskeleton is important in osteoclast function, but Calcitonin disrupts sealing zones without affecting microtubules networks.2006

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[Journal Article] Induction of gicerin/CD146 in the rat carotid artery after balloon injury.2004

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[Journal Article] 骨粗鬆症学-基礎・臨床研究の新しいパラダイム-概論:破骨細胞の分化・骨吸収調節機構2004

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[Journal Article] 液胞型プロトン-ATPaseとアクチンフィラメントの結合2004

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OKUMURA Higeki 奥村茂樹