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takahashi naoyuki  高橋 直之

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TAKAHASHI Naoyuki  高橋 直之

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Researcher Number 90119222
Other IDs
Affiliation (Current) 2022: 松本歯科大学, 総合歯科医学研究所, 特任教授
Affiliation (based on the past Project Information) *help 2016 – 2020: 松本歯科大学, 総合歯科医学研究所, 特任教授
2010 – 2016: 松本歯科大学, 総合歯科医学研究所, 教授
2007 – 2010: Matsumoto Dental University, Graduate School for Dentistry, Professor
2008: 松本歯科大学, 大学院歯学独立研究科, 教授
2005 – 2006: 松本歯科大学, 大学院歯学独立研究科, 教授 … More
2004 – 2005: Matsumoto Dental University, Institute for Dental Science, Professor, 総合歯科医学研究所, 教授
2003 – 2005: Matsumoto Dental University, Graduate School of Oral Medicine, Hard Tissue Research, Professor, 大学院・歯学独立研究科, 教授
2003: 松本歯科大学, 総合歯科・医学研究所, 教授
2001 – 2002: Institute for Dental Science, Professor, 総合歯科医学研究所, 教授
2001: 松本歯科大学, 総合歯科医学研究所・機能解析学, 教授
2000: 昭和大, 歯学部, 助教授
1991 – 2000: Showa Univ., School of Dentistry Associate Professor, 歯学部, 助教授
1997: Showa University, School of Dentistry, Associate Professor, 歯学部, 教授
1987 – 1990: School of Dentistry, Showa University, 歯学部, 講師
1989: 昭和大学, 歯学部・生化学教室, 講師 Less
Review Section/Research Field
Principal Investigator
Functional basic dentistry / Functional basic dentistry / Biological Sciences / General medical chemistry
Except Principal Investigator
Functional basic dentistry / Orthodontic/Pediatric dentistry / Functional basic dentistry / Morphological basic dentistry / Morphological basic dentistry / Orthodontics/Pediatric dentistry … More / Surgical dentistry / Biomedical engineering/Biological material science / Dental engineering/Regenerative dentistry / Basic Section 57010:Oral biological science-related Less
Keywords
Principal Investigator
破骨細胞 / 骨芽細胞 / RANKL / OPG / M-CSF / IL-1 / osteoclast / リポ多糖 / MyD88 / マクロファージ … More / BMP / Smad / ODF / RANK / Nod2 / 骨吸収 / Osteoblast / osteoblast / 骨髄マクロファージ / ムラミルジペプチド / 炎症性サイトカイン / シグナル伝達 / 破骨細胞前駆細胞 / Wnt / 骨代謝共役 / Osteoclast / p60^<c-src> / カルシトニン / 破骨細胞活性化因子 / ビスフォスフォネート / 骨形成 / p38MAPK / p38MAPキナーゼ / カルシウム / 可溶性RANKL / 異所性骨形成 / 口腔生化学 / Wnt / 破骨細胞ニッチ / Wnt5a / Wnt非古典経路 / Wntシグナル / MーCSF / 大理石骨病 / op / opマウス / oc / ocマウス / c-src / 波状縁 / gp130 / IL-6 / IL-11 / 骨誘導因子 / Osteoclasts / Lipopolysaccharide / ビスフォスホネート / TRIF / PGE_2 / ヒトCD14陽性細胞 / TAK1 / 破骨細胞形成抑制因子 / RAW264細胞 / 骨粗鬆症治療薬 / SaOS-4 / 3細胞 / PKC / 破骨細胞分化阻止因子ODIF / OPG欠損マウス / 異所性骨化 / F4 / 80陽性マクロファージ / 石灰化硬組織 / 破骨細胞分化阻止因子(ODIF) / 活性型ビタミンD_3 / IL-34 / Ror2 / 極性化 / 波上縁 / Wnt5a-Ror2シグナル / 低分子量Gタンパク質 / Rho / カーボンナノチューブ / 石灰化 / チタン / エピタキシー因子 / RANKL / OPG / Sclerostin / QOP / マクロファ-ジ / 1α,25(OH)_2D_3 / マクロファ-ジコロニ-刺激因子 / 骨吸収調節因子 / 骨髄由来ストロ-マ細胞 / monocyte / macrophage / 1alpha, 25 (OH) _2D_3 / osteopetosis / cell-cell interaction / マクロファ-ジコロニ-剌激因子 / 活性型ビタミンD / osteopetrosis / macrophage colony stimulating (M-CSF) / 1alpha,25(OH)_2D_3 / 明帯 / ポドソーム / PI-3キナーゼ / 低分子量G蛋白rho / Pl-3キナーゼ / Focal adhesion kinase / ポドソーム形成 / 吸収窩 / ruffled border / clear zone / podosme / calcitonin / PI-3 kinase / small GTP binding protein rho / IL-6レセプター / 慢性関節リウマチ / 可溶性IL-6レセプター / トランスジェニックマウス / 滑液 / IL-6 receptor / osteoclasts / osteoblasts / bone resorption / rheumatoid arthritis / 筋芽細胞 / NF-κB / p130^<Cas> / BMPレセプター / ビスホスフォネート / myoblast / bone morphogenetic protein / bone resorbing factors / signal transduction / NF-kB / 1L-1 / 破骨細胞分化因子(ODF) / osteoprotegerin(OPG) / osteoclastogenesis inhibitory factor(OCIF) / osteoclast activiting factor / 骨粗鬆症 / TNFα / 細胞内Ca / Inflammatory cytokines / Calcium / Osteoporosis / Macrophage / Inflammatory cytokine / p38 MAP kinase / ERK / 骨髄間質細胞 / オステオプロテゲリン / アルカリフォスファターゼ / 骨代謝共役因子 / サイトカイン / Osteoprotegerin (OPG) / Receptor activator of NF-κB (RANKL) / Bisphosphonate / Coupling / soluble RANKL / ectonic bone formation / PGE_2受容体 / インターロイキン1 / 樹状細胞 / Lipopolysaccharide (LPS) / Muramyl dipeptide (MDP) / PGE_2 receptor / 炎症性骨吸収 / リポ多糖(LPS) / ムラミルジペプチド(MDP) / プロスタグランジンE_2 / 骨誘導因子(BMP) / Nod / 小動物用X線CT / ペプチドグリカン / Toll様受容体 / inflammatory bone resorption / Muramyl dipeptide / Prostaglandin E_2 / Bone morphogenetic protein / 細胞周期停止破骨前駆細胞 / Fos欠損マウス / 骨髄細胞マクロファージ / RANK-Cre / プロモデオキシウリジン / Osteoblasts / Cell cycle-arrested quiescent osteoclast precursor / Osteoclast niche / Fos deficient mice / カップリング因子 / クラストカイン / スクレロスチン / LIF / HtrA1 … More
Except Principal Investigator
破骨細胞 / 骨芽細胞 / 骨吸収 / RANKL / OPG / 活性型ビタミンD / BMP / M-CSF / bone resorption / osteoclast / osteoblast / 副甲状腺ホルモン / 骨形成 / Osteoclast / Bone resorption / カルシトニン / 骨粗鬆症 / 破骨細胞前駆細胞 / Osteoblast / 骨誘導因子 / osteoporosis / RANK / マクロファージ / 骨細胞 / PTH / オステオポンチン / Wnt5a / 骨代謝回転 / ビタミンD / マクロファ-ジ / 細胞融合 / GM-CSF / カルシウム / 筋芽細胞 / エストロゲン / IL-1 / ODF / オステオプロテゲリン / リポ多糖 / MyD88 / 細胞分化 / EP4 / op / ヒト破骨細胞 / アルカリフォスファターゼ / カップリングファクター / 免疫組織化学 / OPG遺伝子欠損マウス / NFATc1 / 転写因子 / 加齢 / Wnt / 歯槽骨 / ヒスタチン / LIF / 骨吸収因子 / マクロファ-ジコロニ-刺激因子 / 1alpha, 25(OH)_2D_3 / 補体第3因子 / カルシウム吸収 / ポリアミン / 1alpha, 25-Dihydroxyvitamin D_3 / Osteoclasts / 腎臓 / インターロイキン6 / 骨 / gp130 / ビスフォスフォネート / 波状縁 / bisphosphonates / bone marrow / Hedgehog / myoblast / インターロイキン1 / 骨髄造血 / Bリンパ球 / アンドロゲン / estrogen / hemopoiesis / インターロイキン-7 / 骨代謝 / Smad / IL-7 / エストロゲン受容体 / NF-κB / 受容体 / 遺伝子欠損マウス / OCIF / TNF / Toll-like receptor / EP4 agonist / Fas / in vitro / in vivo / H-ATPase / 歯周疾患 / 炎症性サイトカイン / lipopolysaccharide / Ca^<2+> / 歯周病 / PGE_2 / EP2 / Cre recombinase / 骨改造 / SaOS-2 / 破骨細胞分子因子(ODF) / PTHレセプター / ヒト抹消血単核細胞 / 共存培養 / ヒト抹消血 / 歯胚 / 歯髄 / 歯の再生 / 器官培養 / 移植 / 象牙質シアロタンパク質 / 間葉系幹細胞 / 骨芽細胞前駆細胞 / 象牙芽細胞前駆細胞 / エナメル芽細胞前駆細胞 / 微細形態 / OPG欠損マウス / 歯根膜細胞 / ヒト末梢血 / ヒトCD14陽性細胞 / 破骨細胞形成阻止因子 / ヒト歯根膜 / MAPキナーゼ / カーボンナノチューブ / エピタキシー / 破骨細胞前駆細胞(QuOPs) / 破骨細胞前駆(QuOPs) / エピジェネティック解析 / 歯科矯正学 / 骨芽細胞特異的遺伝子欠損 / 歯の移動 / コンディショナルノックアウト / 天然有機化合物 / 抗癌剤 / 抗がん剤 / 唾液蛋白質 / リン酸化 / 天然化合物 / 質量分析 / ILー6 / インタ-ロイキン1 / GMーCSF / Iγ-4 / Iγ-6 / Osteopontin / Interleukin 1 / Macrophage fusion / Lalpha, 25 (OH) _2D_3 / 分化 / 培養細胞 / レチノイン酸 / 骨肉腫 / differentiation / cell line / retinoic acid / MーCSF / マウス骨髄細胞培養 / 骨吸収調節因子 / 骨髄由来ストロ-マ細胞 / Bone resorbing factors / Macrophage colony stimulating factor / 小腸の吸収上皮細胞 / カルシウムポンプ / 増殖因子 / 小腸上皮細胞細胞 / Intestine epithelial cells / Osteoblasts / Calcium pump / the third component of complement (C3) / Bone resorbing agents / Growth factor / 抗クル病因子 / 肝臓 / 小腸 / インターロイキン11 / ビタミンDレセプター / 1α,25(OH)_2D_3 / 24,25(OH)_2D_3 / calcium absorption / interleukin 6 / interleukin 11 / スクリーニング系 / 破骨細胞形成評価系 / 破骨細胞機能評価系 / アクチンリング / cAMP / ビイフォスフォネート / チロシンフォスファーゼ / 明帯 / ポドソーム / アクチンリング形成 / 骨吸収試験 / 骨吸収評価系 / ポドソーム形成 / 吸収窩 / screening system / osteoclast formation / osteoclast function / pit formation / calcitonin / 転写調節 / 骨髄ストローマ細胞 / ビタミンD欠乏 / 補体第3因子(C3) / C3遺伝子 / complement 3 / stromal cells / vitamin D / macrophage / bone / 軟骨細胞 / 骨髄間質細胞 / 間葉系細胞 / 骨形成因子(BMP) / 筋肉 / ostepblast / chondrocyte / プロスタグランジン / androgen / interleukin-1 / interleukin-6 / 卵巣摘出 / 骨密度 / 骨髄 / B cells / interleukin-7 / ovariectomy / bone mineral density / 骨誘導因子(BMP) / 卵巣摘出術 / 破骨細胞分化因子(ODF) / TNFファミリー / シグナル伝達 / PHT受容体 / IL-6 / Estrogen / インターロイキン18 / インターフェロンγ / Tリンパ球 / Interleukin 18 / Interferon gamma / T-lymphocyte / Gene targetting mouse / 1α-水酸化酵素 / ステロイドホルモン / parathyroid hormone / 1α,25-dihydroxyvitamin D3 / 1α-hydroxylase / 破骨細胞分化因子 / 破骨細胞形成抑制因子 / 骨随間質細胞 / マクロファジーコロニー刺激因子 / 1α, 25(OH)_2D_3 / 骨代謝共役 / Lipopolysaccharide / Lipopeptide / ホルモン / 成長因子 / 転写調節因子 / 血清 / BONE FORMATION / TRANSCRIPTION FACTOR / HORMONE / GROWTH FACTOR / BONE MORPHOGENETIC PROTEIN / OSTEOBLAST / MYOBLAST / CELL DIFFERENTIATION / 石灰化 / カップリング因子 / プロスタグランジンE2 / レーザー / 急速凍結法 / Calcification / Bone formation / Coupling factor / Dental pulp / Laser / 機械刺激 / 細胞死 / 骨リモデリング / タモキシフェン / 機械的刺激 / プロスタグランジンE_2 / PGE_2受容体 / RAW264.7 / p38 MAPK / osteocyte / mechanical stress / apotosis / bone remodeling / estrogen receptor / tamoxifen / カテプシンK / cathepsin K / 菌体成分 / Toll様受容体 / ムラミルジペプチド / periodontal disease / muramyldipeptide / inflammatory cytokine / 骨代謝共役因子 / 象牙芽細胞 / 共役機構 / bone formation / coupling factor / 骨基質 / endocytosis / 細胞内輸送 / transcytosis / vacuole / lysosome / Ca^<+2> / Bone matrix / Endocytosis / Transportation in cell / Transcytosis / Vacuole / Lysosome / 歯肉線維芽細胞(HGF) / 熱ショック蛋白質 / 歯肉線維芽細胞 / 細胞増殖 / 熱ショックタンパク質 / periodontitis / human gingival fibroblast (HGF) / histatins / heat shock proteins / 遺伝子 / 細胞・組織 / 歯学 / 病理学 / 骨代謝学 / 細胞培養 / 電子顕微鏡 / gene / cell・tissue / oral histology / pathology / bone metabolomics / ペプチドグリカン / Nod2 / peptidoglycan / osteoclasts / 歯槽骨吸収 / CD14陽性細胞 / opマウス / リゼドロネート / ビスフォスホネート / Albeolar bone resorption / Human osteoclasts / CD14-positive cells / Osteoclast progenitors / Creリコンビナーゼ / 歯周組織 / ノックインマウス / COX2 / BACクローン / 相同組み換え / orthodontics / osteoclast precursors / 分化誘導因子 / 肺胞マクロファージ / 融合 / トリグリセライド / OAF / DIF / LPS / MGBG / 骨吸収活性 / マクロファージの融合 / 多核巨細胞 / Vitamin D / Macrophages / Cell-fusion / 分化誘導因子(DIF) / 活性型ビタミンD_3(1α,25(OH)_2D_3) / マクロファージ融合因子 / マクロファージ融合因子(MFF) / 骨髄細胞 / コロニー形成因子(CSF) / 1alpha,25-dihydroxyvitamin D_3 [1alpha,25(OH)_2D_3 / differentiation-inducing factor (DIF) / macrophage fusion factor (MFF) / osteoblasts / コラゲナ-ゼ / コラゲナーゼ / collagenase / 1,25(OH)_2D_3 / スペルミジン / トランスグルタミナ-ゼ / Macrophage / Cell Fusion / Calcium / Spermidine / Transglutaminase / 脂肪細胞 / スクレロスチン / Sfrp5 / 骨量 / Pkn3 / Wnt5a / Sfrp5 / 細胞老化 Less
  • Research Projects

    (67 results)
  • Research Products

    (219 results)
  • Co-Researchers

    (100 People)
  •  Does aging of osteocytes adversely affect bone metabolism?

    • Principal Investigator
      yamashita teruhito
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57010:Oral biological science-related
    • Research Institution
      Matsumoto Dental University
  •  Development of alveolar bone turnover control method based on Wnt signaling network

    • Principal Investigator
      Kobayashi Yasuhiro
    • Project Period (FY)
      2016 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Orthodontics/Pediatric dentistry
    • Research Institution
      Matsumoto Dental University
  •  Elucidation of the osteoclast-derived cytokine-Wnt signaling network responsible for coupling between bone resorption and formation.Principal Investigator

    • Principal Investigator
      Takahashi Naoyuki
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General medical chemistry
    • Research Institution
      Matsumoto Dental University
  •  Investigation of factors determining terminal differentiation into osteocytes

    • Principal Investigator
      YAMASHITA Teruhito
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Matsumoto Dental University
  •  How is the formation site of osteoclasts determined?Principal Investigator

    • Principal Investigator
      Takahashi Naoyuki
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Functional basic dentistry
    • Research Institution
      Matsumoto Dental University
  •  Elucidation of Wnt signaling network controlling bone metabolismPrincipal Investigator

    • Principal Investigator
      Takahashi Naoyuki
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Matsumoto Dental University
  •  骨代謝共役を担うWntシグナルの解明Principal Investigator

    • Principal Investigator
      高橋 直之
    • Project Period (FY)
      2013
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Matsumoto Dental University
  •  Development of alveolar bone turnover control method based on Wnt5a

    • Principal Investigator
      Kobayashi Yasuhiro
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Orthodontics/Pediatric dentistry
    • Research Institution
      Matsumoto Dental University
  •  Novel mechanism of regulating the activity of the transcription factor NFATc1 in bone metabolism

    • Principal Investigator
      YAMASHITA Teruhito
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Matsumoto Dental University
  •  Do carbon nanotubes control bone remodeling?Principal Investigator

    • Principal Investigator
      TAKAHASHI Naoyuki
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Functional basic dentistry
    • Research Institution
      Matsumoto Dental University
  •  Elucidation of the mechanism of action in salivary protein histatin aimed at soft tissue injury treatment and regenerative medicine

    • Principal Investigator
      IMAMURA Yasuhiro
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Dental engineering/Regenerative dentistry
    • Research Institution
      Matsumoto Dental University
  •  Analysis of osteoclast niche regulated by Wnt signals.Principal Investigator

    • Principal Investigator
      TAKAHASHI Naoyuki
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Matsumoto Dental University
  •  Role of Wnt-Ror2 signals in ruffled border formation in osteoclastsPrincipal Investigator

    • Principal Investigator
      TAKAHASHI Naoyuki
    • Project Period (FY)
      2010 – 2011
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Functional basic dentistry
    • Research Institution
      Matsumoto Dental University
  •  Analysis of roles of Wnt5a in alveolar bone remodeling, and their application for orthodontic tooth movement.

    • Principal Investigator
      KOBAYASHI Yasuhiro
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Orthodontic/Pediatric dentistry
    • Research Institution
      Matsumoto Dental University
  •  Elucidation of the novel inhibitory mechanism of anti-tumor drug arctigenin on bone resorption

    • Principal Investigator
      YAMASHITA Teruhito
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Matsumoto Dental University
  •  Analysis of molecular mechanism of carbon nanotube regulating bone metabolism

    • Principal Investigator
      MIZOGUCHI Toshihide
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research a proposed research project)
    • Research Field
      Functional basic dentistry
      Biomedical engineering/Biological material science
    • Research Institution
      Matsumoto Dental University
  •  Analysis of novel MAP kinase binding factor which regulates osteoclasts

    • Principal Investigator
      YAMASHITA Teruhito
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Matsumoto Dental University
  •  The relationship between cell proliferation and RANKL-induced osteoclastogenesisPrincipal Investigator

    • Principal Investigator
      TAKAHASHI Naoyuki
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Matsumoto Dental University
  •  Application of Cre-loxP system for elucidation of mechanisms in bone remodeling during tooth movement

    • Principal Investigator
      KOBAYASHI Yasuhiro
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Orthodontic/Pediatric dentistry
    • Research Institution
      Matsumoto Dental University
  •  Effects of osteoprotegerin administration on osteoclast differentiation and trabecular bone structure in osteoprotegerin-deficient mice.

    • Principal Investigator
      MAYAHARA Mitsuori, 佐々木 崇寿
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Showa University
  •  Analysis of the Nod signals which enhance bone resorption

    • Principal Investigator
      YANG Shufa
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Surgical dentistry
    • Research Institution
      Matsumoto Dental University
  •  Elucidation of molecular mechanism of alveolar bone remodeling induced by orthodontic force.

    • Principal Investigator
      KURIHARA Saburo
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthodontic/Pediatric dentistry
    • Research Institution
      Matsumoto Dental University
  •  再生骨および歯と受容者(recipient)組織間の特異的相互作用の解析

    • Principal Investigator
      小澤 英浩
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Matsumoto Dental University
  •  歯根膜組織に存在する歯根吸収を抑制する新規因子の探索

    • Principal Investigator
      二宮 禎
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Orthodontic/Pediatric dentistry
    • Research Institution
      Matsumoto Dental University
  •  Study on the molecular mechanism of alveolus bone resorption induced periodontal diseasesPrincipal Investigator

    • Principal Investigator
      TAKAHASHI Naoyuki
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Matsumoto Dental University
  •  Ca^<2+> kinetics in mature osteoclast

    • Principal Investigator
      YAMAKI Mariko
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Matsumoto Dental University
  •  Elucidation of receptors for salivary protein histatin in human gingival fibroblast

    • Principal Investigator
      IMAMURA Yasuhiro
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Matsumoto Dental University
  •  破骨細胞分化阻止因子(ODIF)のクローニングと生理的役割の解析Principal Investigator

    • Principal Investigator
      高橋 直之
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Functional basic dentistry
    • Research Institution
      Matsumoto Dental University
  •  The establishment of inducible osteocyte ablation mouse model to elucidate the mechanisms of maxillo-mandibular dysmorphia.

    • Principal Investigator
      HOSOYA Akihiro, 小林 泰浩
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Orthodontic/Pediatric dentistry
    • Research Institution
      Matsumoto Dental University
  •  Establishment of Bone Metabolism Research through Regulation of Osteoclast Differentiation and Functions

    • Principal Investigator
      SASAKI Takahisa
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Showa University
  •  The possible mechanism of alveolar bone destruction induced by constituent of gram-negative bacteria.

    • Principal Investigator
      SHUHUA Yang
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Surgical dentistry
    • Research Institution
      Matsumoto Dental University
  •  Analysis of tooth development of osteoprotegerin- deficient mice

    • Principal Investigator
      NAKAMURA Hiroshi
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthodontic/Pediatric dentistry
    • Research Institution
      Matsumoto Dental University
  •  Analysis of molecular mechanisms in bone formation and regeneration

    • Principal Investigator
      OZAWA Hidehiro
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Matsumoto Dental University
  •  Signal transduction and cell-to-cell communication in the bone resorption induced by inflammationPrincipal Investigator

    • Principal Investigator
      TAKAHASHI Naoyuki
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Matsumoto Dental University
  •  骨芽細胞及びリンパ球の分化を促進する破骨細胞由来新規サイトカインの同定

    • Principal Investigator
      宇田川 信之
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Functional basic dentistry
    • Research Institution
      Matsumoto Dental University
      Showa University
  •  Analysis of signal transduction of osteoclast differentiation factor (RANKL) in alveolar bone destruction

    • Principal Investigator
      UDAGAWA Nobuyuki
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Matsumoto Dental University
  •  Study on mechanism of the coupling between bone resorption and bone formationPrincipal Investigator

    • Principal Investigator
      TAKAHASHI Naoyuki
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Matsumoto Dental University
  •  CHARACTERIZATION OF THE BONE FORMING FACTORS IN SERUM

    • Principal Investigator
      KATAGIRI Takenobu
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional basic dentistry
    • Research Institution
      SHOWA UNIVERSITY
  •  破骨細胞を調節するシグナル伝達系と骨・歯周疾患における骨破壊機序の解明Principal Investigator

    • Principal Investigator
      高橋 直之
    • Project Period (FY)
      2000 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Matsumoto Dental University
      Showa University
  •  Analysis of signal transduction of inflammatory cytokines in bone destructionPrincipal Investigator

    • Principal Investigator
      TAKAHASHI Naoyuki
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Functional basic dentistry
    • Research Institution
      MATSUMOTO DENTAL UNIVERSITY
      Showa University
  •  破骨細胞の融合機構とその生理的意義の解明Principal Investigator

    • Principal Investigator
      高橋 直之
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Functional basic dentistry
    • Research Institution
      Showa University
  •  The physiological role of osteoclast differentiation factor.

    • Principal Investigator
      UDAGAWA Nobuyuki
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Functional basic dentistry
    • Research Institution
      Showa University
  •  Study on signal transduction in osteoclastogenesis for the development of anti-osteoporosis drugs.Principal Investigator

    • Principal Investigator
      TAKAHASHI Naoyuki
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Functional basic dentistry
    • Research Institution
      Showa University
  •  The roles of nuclear transcription factors in calcium homeostasis

    • Principal Investigator
      SUDA Tatsuo
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Showa University
  •  Study on osteoclast activiting factor expressed by osteoblasts/stromal cellsPrincipal Investigator

    • Principal Investigator
      TAKAHASHI Naoyuki
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Showa University
  •  ヒトPTH受容体遺伝子の導入によるヒト破骨細胞形成系の確立

    • Principal Investigator
      SUDA Tatsuo
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Functional basic dentistry
    • Research Institution
      Showa University
  •  Mechanism of osteoclastogenesis inhibitory action by interleukin 18

    • Principal Investigator
      UDAGAWA Nobuyuki, 宇田川 信之
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Showa University
  •  Pathogenesis of bone loss due to estrogen deficiency : Relationship between increased B-lymphopoiesis and bone resorption.

    • Principal Investigator
      SUDA Tatsuo
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Showa University
  •  Development of bone metabolism improvement medicines based on the analysis of signal transduction

    • Principal Investigator
      SUDA Tasuo
    • Project Period (FY)
      1996 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Showa University
  •  Analysis of gp130-induced signals which regulate osteclast formation and functionPrincipal Investigator

    • Principal Investigator
      TAKAHASHI Naoyuki
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Showa University
  •  Establishment of assay systems for examining bone metabolism : Studies on differentiation and function of osteoblasts and osteoclastsPrincipal Investigator

    • Principal Investigator
      TAKAHASHI Naoyuki
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Showa University
  •  Role of BMPs in differentiation process of osteoblasts, chondrocytes and muscle cells

    • Principal Investigator
      YOSHIKI Susaku
    • Project Period (FY)
      1994 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Showa University
  •  Molecular mechanisms of osteoporosis induced by estrogen deficiency.

    • Principal Investigator
      SUDA Tatsuo
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Showa University
  •  Analysis of signaling pathways involved in polarization of osteoclasts.Principal Investigator

    • Principal Investigator
      TAKAHASHI Naoyuki
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Showa University
  •  Development of reliable screening systems for drugs which regulate bone resorption : In vitro assay systems for osteoclast formation and function.

    • Principal Investigator
      SUDA Tatsuo
    • Project Period (FY)
      1993 – 1995
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Showa University
  •  Production and biological roles of the third component of complement in bone.

    • Principal Investigator
      MIYAURA Chisato
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Showa University
  •  Molecular aspects of vitamin D metabolism and action

    • Principal Investigator
      SUDA Tatsuo
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Showa University
  •  Study on Interaction between Osteoclast Progenitors and Osteoblastic Cells in Osteoclast Development.Principal Investigator

    • Principal Investigator
      TAKAHASHI Naoyuki
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Showa University
  •  Basic study on the risk factors of osteoporosis.

    • Principal Investigator
      SUDA Tatsuo
    • Project Period (FY)
      1990 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Showa University
  •  The Role of Cytokines in Bone Resorption and Bone Formation

    • Principal Investigator
      ABE Etsuko
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Showa University
  •  Rolo of Osteoblastic Cells in Osteoclast Development.Principal Investigator

    • Principal Investigator
      TAKAHASHI Naoyuki
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Showa University
  •  Establishment of Assay System for Studying Osteoblastic Function and Differentiation Using Newly Isolated Osteoblast-Like Cell Lines

    • Principal Investigator
      YOSHIKI Shusaku
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B).
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Showa University
  •  Establishment of the screening methods for bone-resorbing factors using in vitro osteoclast formation system.

    • Principal Investigator
      SUDA Tatsuo
    • Project Period (FY)
      1989 – 1991
    • Research Category
      Grant-in-Aid for Developmental Scientific Research
    • Research Field
      Functional basic dentistry
    • Research Institution
      Showa University
  •  Role of the osteoclast and osteoblast during the bone resorption

    • Principal Investigator
      YOSHIKI Shusaku
    • Project Period (FY)
      1988 – 1989
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Showa University
  •  Two step model for the fusion of macrophages induced by 1alpha, 25-dihydroxyvitamin D_3

    • Principal Investigator
      SUDA Tatsuo
    • Project Period (FY)
      1988 – 1989
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Showa University
  •  Development of new assay systems for examining the relation between osteoblasts and osteoclasts, and identification of new factors controlling bone metabolism

    • Principal Investigator
      SUDA Tatsuo
    • Project Period (FY)
      1986 – 1988
    • Research Category
      Grant-in-Aid for Developmental Scientific Research
    • Research Field
      Functional basic dentistry
    • Research Institution
      Showa University, School of Dentistry
  •  Mechanisms of Fusion of Macrophages Induced by 1 ,25(OH)_2D_3

    • Principal Investigator
      SUDA Tatsuo
    • Project Period (FY)
      1985 – 1987
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Showa University

All 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 Other

All Journal Article Presentation Book

  • [Book] "破骨細胞はどのようにして骨組織にのみ形成されるのか"骨代謝実験医学臨時増刊号(田中栄編)2014

    • Author(s)
      高橋直之(分担執筆)
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PROJECT-24659833
  • [Book] "ビスホスホネートの作用機構"ファーマナビゲータービスホスホネート編2(松本俊夫、萩野浩編)2013

    • Author(s)
      小出雅則,高橋直之(分担執筆)
    • Publisher
      メディカルレビュー社
    • Data Source
      KAKENHI-PROJECT-24659833
  • [Book] "カルシトニンと骨・ミネラル代謝"副甲状腺・骨代謝疾患診療マニュアル(竹内靖博編)2013

    • Author(s)
      小出雅則,高橋直之(分担執筆)
    • Publisher
      診断と治療社
    • Data Source
      KAKENHI-PROJECT-24659833
  • [Book] "ビタミンDのカルシウム代謝調節機構"ファーマナビゲーター活性型ビタミンD_3製剤編(太田博明、松本俊夫編)2012

    • Author(s)
      高橋直之(分担執筆)
    • Publisher
      メディカルレビュー社
    • Data Source
      KAKENHI-PROJECT-24659833
  • [Book] Identification of osteoclasts in culture2011

    • Author(s)
      Udagawa N, Yamashita T, Kobayashi Y, Takahashi N, Nicole I zur Nieden
    • Publisher
      Springer Science
    • Data Source
      KAKENHI-PROJECT-21390551
  • [Book] Identification of osteoclasts in culture. In Embryonic Stem Cell Therapy for Osteo-Degenerative Diseases Series Methods in Molecular Biology2011

    • Author(s)
      Udagawa N, Yamashita T, Kobayashi Y, Takahashi N, Walker JM, zur Nieden NI
    • Publisher
      Humana Press
    • Data Source
      KAKENHI-PROJECT-21592378
  • [Book] Principles of bone biology. Third edition, ed by Raisz LG, Martin TJ, Bilezikian JP2008

    • Author(s)
      Naoyuki Takahashi, et. al.
    • Total Pages
      1700
    • Publisher
      Academic Press
    • Data Source
      KAKENHI-PROJECT-18390557
  • [Book] Current paradigms of osteoblast-osteoclast interactions and bacterial pathogen-induced bone resorption. In Periodontal Medicine and Systems Biology2008

    • Author(s)
      Takahashi N
    • Publisher
      Blackwell Publishing,Oxford(In press)
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18390495
  • [Book] Principles of bone biology.Third edition, ed by Raisz LG, Martin TJ, Bilezikian JP2008

    • Author(s)
      Naoyuki Takahashi, et. al.
    • Total Pages
      1700
    • Publisher
      Academic Press
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18390557
  • [Book] Current paradigms of osteoblast-osteoclast interactions and bacterial pathogen-induced bone resorption.In Periodontal Medicine and Systems Biology2008

    • Author(s)
      Takahashi N
    • Publisher
      Academic Press,San Diego(In press)
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18390495
  • [Book] Methods in Molecular Medicine ed by Cope A. P.2007

    • Author(s)
      Naoyuki Takahashi, et. al.
    • Total Pages
      430
    • Publisher
      Humana Press
    • Data Source
      KAKENHI-PROJECT-18390557
  • [Book] Arthritis Research, Methods and Protocols Volume 1 "Generation of osteoclasts in vitro, and assay of osteoclast activity"2006

    • Author(s)
      Takahashi N et al.
    • Publisher
      Humana Press
    • Data Source
      KAKENHI-PROJECT-18390495
  • [Book] Generation of osteoclasts in vitro, and assay of osteoclast activity. In "Arthritis Research, Methods and Protocols Volume 1"(ed by Cop A.)2006

    • Author(s)
      Takahashi N.
    • Total Pages
      16
    • Publisher
      Humana Press
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591924
  • [Book] Arthritis Research, Methods and Protocols Volume 1 "Generation of osteoclasts in vitro, and assay of osteoclast activity"2006

    • Author(s)
      Takahashi N et al.
    • Publisher
      Humana Press
    • Data Source
      KAKENHI-PROJECT-17592119
  • [Book] Generation of osteoclasts in vitro, and assay of osteoclast activity. In "Arthritis Research, Methods and Protocols Volume 1" ed by Cop A2006

    • Author(s)
      Takahashi N.
    • Total Pages
      16
    • Publisher
      Humana Press
    • Data Source
      KAKENHI-PROJECT-17591924
  • [Book] Arthritis Research : Methods and Protocols2005

    • Author(s)
      Takahashi N et al.
    • Publisher
      Humana Press, Totowa, New Jersey (in press)
    • Data Source
      KAKENHI-PROJECT-12137209
  • [Book] Arthritis Research : Methods and Protocols2005

    • Author(s)
      Takahashi N et al.
    • Publisher
      Humana Press, Totowa, New Jersey (in press)
    • Data Source
      KAKENHI-PROJECT-15659445
  • [Book] Arthritis Research : Methods and Protocols2005

    • Author(s)
      Takahashi N et al.
    • Publisher
      Humana Press, Totowa, New Jersey(in press)
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15592144
  • [Book] Arthritis Research : Methods and Protocols2005

    • Author(s)
      Takahashi N et al.
    • Publisher
      Humana Press, Totowa, New Jersey(in press)
    • Data Source
      KAKENHI-PROJECT-16390535
  • [Book] 硬組織研究ハンドブック2005

    • Author(s)
      高橋直之他
    • Total Pages
      264
    • Publisher
      松本歯科大学出版
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390535
  • [Book] Arthritis Research : Methods and Protocols2005

    • Author(s)
      Takahashi N et al.
    • Publisher
      Humana Press, Totowa, New Jersey (in press)
    • Data Source
      KAKENHI-PROJECT-16659578
  • [Book] Arthritis Research : Methods and Protocols2005

    • Author(s)
      Takahashi N et al.
    • Publisher
      Humana Press, Totowa, New Jersey(in press)
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15592180
  • [Book] Arthritis Research : Methods and Protocols2005

    • Author(s)
      Takahashi N et al.
    • Publisher
      Humana Press, Totowa, New Jersey(in press)
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390641
  • [Journal Article] Sclerostin expression in trabecular bone is downregulated by osteoclasts2020

    • Author(s)
      Masanori Koide, Teruhito Yamashita, Kohei Murakami, Shunsuke Uehara, Keigo Nakamura, Midori Nakamura, Mai Matsushita, Toshiaki Ara, Hisataka Yasuda, Josef M Penninger, Naoyuki Takahashi, Nobuyuki Udagawa, Yasuhiro Kobayashi
    • Journal Title

      Scientific Reports

      Volume: 10 Pages: 13751-13751

    • DOI

      10.1038/s41598-020-70817-1

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K10050, KAKENHI-PROJECT-19K10395, KAKENHI-PROJECT-19K22729, KAKENHI-PROJECT-20K21689, KAKENHI-PROJECT-16H02691, KAKENHI-PROJECT-17H01584, KAKENHI-PROJECT-18H02980, KAKENHI-PROJECT-18K09531, KAKENHI-PROJECT-19K18955
  • [Journal Article] Murine osteoclasts secrete serine protease HtrA1 capable of degrading osteoprotegerin in the bone microenvironment.2019

    • Author(s)
      Ochiai Nagahiro、Nakachi Yutaka、Yokoo Tomotaka、Ichihara Takahiro、Eriksson Tore、Yonemoto Yuki、Kato Takehiko、Ogata Hitoshi、Fujimoto Natsuko、Kobayashi Yasuhiro、Udagawa Nobuyuki、Kaku Shinsuke、Ueki Tomokazu、Okazaki Yasushi、Takahashi Naoyuki、Suda Tatsuo
    • Journal Title

      Commun Biol

      Volume: 2 Pages: 1-13

    • DOI

      10.1038/s42003-019-0334-5

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K08487, KAKENHI-PROJECT-16H05144, KAKENHI-PROJECT-19K10395, KAKENHI-PROJECT-16H02691, KAKENHI-PROJECT-20K20394, KAKENHI-PROJECT-17K19776
  • [Journal Article] Parathyroid hormone shifts cell fate of a leptin receptor-marked stromal population from adipogenic to osteoblastic lineage.2019

    • Author(s)
      Yang M, Arai A, Udagawa N, Zhao L, Nishida D, Murakami K, Hiraga T, Takao-Kawabata R, Matsuo K, Komori T, Kobayashi Y, Takahashi N, Isogai Y, Ishizuya T, Yamaguchi A, Mizoguchi T
    • Journal Title

      Journal of Bone and Mineral Research

      Volume: 34 Pages: 1952-1963

    • DOI

      10.1002/jbmr.3811

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K10395, KAKENHI-PROJECT-18K19656, KAKENHI-PROJECT-19K18955, KAKENHI-PROJECT-16H02691, KAKENHI-PROJECT-20K20394, KAKENHI-PROJECT-17K19776, KAKENHI-PROJECT-17H04374, KAKENHI-PROJECT-19H03833
  • [Journal Article] Mechanisms involved in bone resorption regulated by vitamin D.2018

    • Author(s)
      Nakamichi Yuko、Udagawa Nobuyuki、Suda Tatsuo、Takahashi Naoyuki
    • Journal Title

      J Steroid Biochem Mol Biol

      Volume: 177 Pages: 70-76

    • DOI

      10.1016/j.jsbmb.2017.11.005

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H05144, KAKENHI-PROJECT-17K19776, KAKENHI-PROJECT-16H05508, KAKENHI-PROJECT-16K11493, KAKENHI-PROJECT-16K11818, KAKENHI-PROJECT-15KK0356
  • [Journal Article] A Jak1/2 inhibitor, baricitinib, inhibits osteoclastogenesis by suppressing RANKL expression in osteoblasts in vitro2017

    • Author(s)
      Murakami K, Kobayashi Y, Uehara S, Suzuki T, Koide M, Yamashita T, Nakamura M, Takahashi N, Kato H, Udagawa N and Nakamura Y
    • Journal Title

      PLoS One

      Volume: 12

    • DOI

      10.1371/journal.pone.0181126

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K11494, KAKENHI-PROJECT-17K16686, KAKENHI-PROJECT-16H02691, KAKENHI-PROJECT-16H05144, KAKENHI-PROJECT-15K11028, KAKENHI-PROJECT-15K11377, KAKENHI-PROJECT-15K11401
  • [Journal Article] VDR in osteoblast-lineage cells primarily mediates vitamin D treatment-induced increase in bone mass by suppressing bone resorption.2017

    • Author(s)
      Nakamichi Y, Udagawa N, Horibe K, Mizoguchi T, Yamamoto Y, Nakamura T, Hosoya A, Kato S, Suda T, Takahashi N
    • Journal Title

      Journal of Bone and Mineral Research

      Volume: 32 Pages: 1297-1308

    • DOI

      10.1002/jbmr.3096

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-16H05144, KAKENHI-PROJECT-26462826, KAKENHI-PROJECT-16K11493, KAKENHI-PROJECT-16K11664, KAKENHI-PROJECT-16K11818, KAKENHI-PROJECT-17K19776, KAKENHI-PROJECT-15KK0356, KAKENHI-PROJECT-16H05508, KAKENHI-PROJECT-17H04374, KAKENHI-PROJECT-15K11093
  • [Journal Article] Treatment of OPG-deficient mice with WP9QY, a RANKL-binding peptide, recovers alveolar bone loss by suppressing osteoclastogenesis and enhancing osteoblastogenesis.2017

    • Author(s)
      Ozaki Yuki、Koide Masanori、Furuya Yuriko、Ninomiya Tadashi、Yasuda Hisataka、Nakamura Midori、Kobayashi Yasuhiro、Takahashi Naoyuki、Yoshinari Nobuo、Udagawa Nobuyuki
    • Journal Title

      PLoS One

      Volume: 12

    • DOI

      10.1371/journal.pone.0184904

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H02691, KAKENHI-PROJECT-16H05144, KAKENHI-PROJECT-15K11028, KAKENHI-PROJECT-15K11093, KAKENHI-PROJECT-15K11401, KAKENHI-PROJECT-15K11402
  • [Journal Article] Bone Formation Is Coupled to Resorption Via Suppression of Sclerostin Expression by Osteoclasts2017

    • Author(s)
      Koide M, Kobayashi Y, Yamashita T, Uehara S, Nakamura M, Hiraoka BY, Ozaki Y, Iimura T, Yasuda H, Takahashi N and Udagawa N
    • Journal Title

      Journal of Bone and Mineral Research

      Volume: 32 Pages: 2074-2086

    • DOI

      10.1002/jbmr.3175

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K11494, KAKENHI-PROJECT-26293392, KAKENHI-PROJECT-16H02691, KAKENHI-PROJECT-16H05144, KAKENHI-PROJECT-15K11028, KAKENHI-PROJECT-15K11059, KAKENHI-PROJECT-15K11377, KAKENHI-PROJECT-15K11401, KAKENHI-PROJECT-15K11402
  • [Journal Article] Protein kinase N3 promotes bone resorption by osteoclasts in response to Wnt5a-Ror2 signaling2017

    • Author(s)
      Uehara S, Udagawa N, Mukai H, Ishihara A, Maeda K, Yamashita T, Murakami K, Nishita M, Nakamura T, Kato S, Minami Y, Takahashi N and Kobayashi Y
    • Journal Title

      Sci. Signaling

      Volume: 10

    • DOI

      10.1126/scisignal.aan0023

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K11494, KAKENHI-PROJECT-16K11818, KAKENHI-PROJECT-17K07168, KAKENHI-PROJECT-17K08634, KAKENHI-PROJECT-17K19776, KAKENHI-PROJECT-17K16686, KAKENHI-PROJECT-16H02691, KAKENHI-PROJECT-16H05144, KAKENHI-PROJECT-16H05152, KAKENHI-PROJECT-16H05508, KAKENHI-PROJECT-15K11059, KAKENHI-PROJECT-15K11377
  • [Journal Article] Platypus and opossum calcitonins exhibit strong activities, even though they belong to mammals.2017

    • Author(s)
      Yamashita T, Udagawa N, Thirukonda GJ, Uehara S, Yamauchi H, Suzuki N, Li F, Kobayashi Y, Takahashi N.
    • Journal Title

      Gen Comp Endocrinol

      Volume: 246 Pages: 270-278

    • DOI

      10.1016/j.ygcen.2017.01.001

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26462825, KAKENHI-PROJECT-15K15688, KAKENHI-PROJECT-15K11059, KAKENHI-PROJECT-16K11494, KAKENHI-PROJECT-16K11818, KAKENHI-PROJECT-17K19776, KAKENHI-PROJECT-16H02691, KAKENHI-PROJECT-16H05144, KAKENHI-PROJECT-16H05508
  • [Journal Article] Osteogenic factor Runx2 marks a subset of leptin receptor-positive cells that sit atop the bone marrow stromal cell hierarch.2017

    • Author(s)
      Yang Mengyu、Arai Atsushi、Udagawa Nobuyuki、Hiraga Toru、Lijuan Zhao、Ito Susumu、Komori Toshihisa、Moriishi Takeshi、Matsuo Koichi、Shimoda Kouji、Zahalka Ali H.、Kobayashi Yasuhiro、Takahashi Naoyuki、Mizoguchi Toshihide
    • Journal Title

      Sci Rep

      Volume: 7 Pages: 4298-4298

    • DOI

      10.1038/s41598-017-05401-1

    • NAID

      120006576162

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K11798, KAKENHI-PROJECT-16K11818, KAKENHI-PROJECT-17K19776, KAKENHI-PROJECT-16H02691, KAKENHI-PROJECT-16H05144, KAKENHI-PROJECT-16H05508, KAKENHI-PROJECT-17H04374, KAKENHI-PROJECT-15K11028, KAKENHI-PROJECT-15K11048, KAKENHI-PROJECT-15K11093, KAKENHI-PROJECT-16K15781, KAKENHI-PROJECT-26221310
  • [Journal Article] The dynamin inhibitor dynasore inhibits bone resorption by rapidly disrupting actin rings of osteoclasts.2016

    • Author(s)
      Thirukonda GJ, Uehara S, Nakayama T, Yamashita T, Nakamura Y, Mizoguchi T, Takahashi N, Yagami K, Udagawa N, Kobayashi Y
    • Journal Title

      J Bone Miner Metab

      Volume: 34

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25221310
  • [Journal Article] The dynamin inhibitor dynasore inhibits bone resorption by rapidly disrupting actin rings of osteoclasts2016

    • Author(s)
      Thirukonda GJ, Uehara S, Nakayama T, Yamashita T, Nakamura Y, Mizoguchi T, Takahashi N, Yagami K, Udagawa N, Kobayashi Y.
    • Journal Title

      J Bone Miner Metab

      Volume: 34 Pages: 395-405

    • DOI

      10.1007/s00774-015-0683-1

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26462825, KAKENHI-PROJECT-16H02691, KAKENHI-PROJECT-16H05144, KAKENHI-PROJECT-26462826, KAKENHI-PROJECT-15K11059, KAKENHI-PROJECT-16K11664
  • [Journal Article] Regulation of bone metabolism by Wnt signals.2016

    • Author(s)
      Kobayashi Y, Uehara S, Koide M, Takahashi N
    • Journal Title

      J Biochem.

      Volume: 4 Pages: 387-392

    • DOI

      10.1093/jb/mvv124

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K11401, KAKENHI-PROJECT-26462826, KAKENHI-PROJECT-25462904, KAKENHI-PROJECT-25462905, KAKENHI-PROJECT-25293423, KAKENHI-PROJECT-16H02691, KAKENHI-PROJECT-16H05144, KAKENHI-PROJECT-16H05508, KAKENHI-PROJECT-15K11377, KAKENHI-PROJECT-16K11818
  • [Journal Article] Platypus and opossum calcitonins exhibit strong activities, even though they belong to mammals.2016

    • Author(s)
      Yamashita T, Udagawa N, Thirukonda GJ, Uehara S, Yamauchi H, Suzuki N, Li F, Kobayashi Y, Takahashi N
    • Journal Title

      Gen Comp Endocrinol

      Volume: 246 Pages: 270-278

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-16H05144
  • [Journal Article] Luman, an ER membrane-bound transcription factor, is involved in osteoclastogenesis through the regulation of DC-STAMP expression, stability and localization.2015

    • Author(s)
      Kanemoto S, Kobayashi Y, Yamashita T, Miyamoto T, Cui M, Asada R, Cui X, Hino K, Kaneko M, Takai T, Matsuhisa K, Takahashi N, Imaizumi K.
    • Journal Title

      Journal of Cell Science

      Volume: 128 Pages: 4353-4365

    • DOI

      10.1242/jcs.176057

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26462825, KAKENHI-PROJECT-15K19516, KAKENHI-PROJECT-15K20001, KAKENHI-PROJECT-25221310, KAKENHI-PROJECT-25251014, KAKENHI-PROJECT-13J00677, KAKENHI-PROJECT-26670814, KAKENHI-PROJECT-15K18377, KAKENHI-PROJECT-15K21706
  • [Journal Article] Wnt16 regulates osteoclast differentiation in conjunction with Wnt5a2015

    • Author(s)
      Kobayashi Y, Thirukonda GJ, Nakamura Y, Koide M, Yamashita T, Uehara S, Kato H, Udagawa N, Takahashi N
    • Journal Title

      Biochem Biopys Res Commun

      Volume: 463 Pages: 1278-1283

    • DOI

      10.1016/j.bbrc.2015.06.102

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K11059, KAKENHI-PROJECT-15K11401, KAKENHI-PROJECT-26462825, KAKENHI-PROJECT-26462826, KAKENHI-PROJECT-15K15688, KAKENHI-PROJECT-25221310, KAKENHI-PROJECT-25462904, KAKENHI-PROJECT-25462905, KAKENHI-PROJECT-26670814, KAKENHI-PROJECT-25293423
  • [Journal Article] The regulation of osteoclast differentiation by Wnt signals.2015

    • Author(s)
      Kobayashi Y, Uehara S, Koide M, Takahashi N
    • Journal Title

      Bone Key Rep

      Volume: 4 Pages: 713-713

    • DOI

      10.1038/bonekey.2015.82

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25221310, KAKENHI-PROJECT-25670792, KAKENHI-PROJECT-26670814, KAKENHI-PROJECT-25293423
  • [Journal Article] Osteoclast Cell Lineage2014

    • Author(s)
      Takahashi N, Mizoguchi T, Nakamichi Y, Kobayashi Y, Nakamura M, Willy Hofstetter W, Udagawa N
    • Journal Title

      Characteristics and behavior of osteoclast precursors in vivo Encyclopedia of Human Body 3^<rd> Edition

      Volume: (in press)

    • Data Source
      KAKENHI-PROJECT-24659833
  • [Journal Article] IL-34 and CSF-1 : similarities and differences2014

    • Author(s)
      Nakamichi Y, Udagawa N, Takahashi N
    • Journal Title

      J Bone Miner Metab

      Volume: 31 Pages: 486-495

    • DOI

      10.1007/s00774-013-0476-3

    • NAID

      10031201682

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23593054, KAKENHI-PROJECT-24659833, KAKENHI-PROJECT-25221310, KAKENHI-PROJECT-25462905, KAKENHI-PROJECT-25670793
  • [Journal Article] Stability of mRNA influences osteoporotic bone mass via CNOT32014

    • Author(s)
      Watanabe, C. Morita, M. Yamamoto T. (13名)
    • Journal Title

      Proc Natl Acac Sci USA

      Volume: Vol.111 Pages: 111-118

    • DOI

      10.1073/pnas.1316932111

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21229006, KAKENHI-PROJECT-23390471, KAKENHI-PROJECT-24659833, KAKENHI-PUBLICLY-25121734, KAKENHI-PROJECT-25221310, KAKENHI-PROJECT-25293423, KAKENHI-PROJECT-25462287, KAKENHI-PROJECT-25463168, KAKENHI-PROJECT-25670639, KAKENHI-PROJECT-25670792, KAKENHI-PROJECT-26670814
  • [Journal Article] Arctigenin inhibits osteoclast differentiation and function by suppressing both calcineurin-dependent and osteoblastic cell-dependent NFATc1 pathways2014

    • Author(s)
      Yamashita T, Uehara S, Udagawa N, Li F, Kadota S, Esumi H, Kobayashi Y, Takahashi N
    • Journal Title

      PLOS ONE

      Volume: 9 Pages: 1-12

    • DOI

      10.1371/journal.pone.0085878

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-23593054, KAKENHI-PROJECT-24390417, KAKENHI-PROJECT-24592821, KAKENHI-PROJECT-24659833, KAKENHI-PROJECT-25221310, KAKENHI-PROJECT-25293423, KAKENHI-PROJECT-25462904, KAKENHI-PROJECT-25670792, KAKENHI-PROJECT-25670793, KAKENHI-PROJECT-26462825, KAKENHI-PROJECT-26670814
  • [Journal Article] Vitamin D endocrine system and osteoclasts Vitamin D and Bone2014

    • Author(s)
      Takahashi N, Udagawa N, Suda T
    • Journal Title

      Bone Key

      Volume: 3 Pages: 495-495

    • DOI

      10.1038/bonekey.2013.229

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-23593054, KAKENHI-PROJECT-25221310, KAKENHI-PROJECT-26670814
  • [Journal Article] Roles of cathelicidins in inflammation and bone loss.2014

    • Author(s)
      Nakamichi Y, Horibe K, Udagawa N, Takahashi N
    • Journal Title

      Odontology

      Volume: 101 Pages: 137-146

    • DOI

      10.1007/s10266-014-0167-0

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25221310, KAKENHI-PROJECT-25462905, KAKENHI-PROJECT-26670814
  • [Journal Article] Osteoclasts polarize on dental implant materials as if they were on bone2014

    • Author(s)
      Nakayama T, Thirukond GJ, Nagasaw S, Kawahara I, Udagawa N, Yagami K, Kawatani M, Osada H, Doi Y, Yoshinaria N, Takahashi N
    • Journal Title

      J Oral Biosci

      Volume: (in press)

    • Data Source
      KAKENHI-PROJECT-24659833
  • [Journal Article] Noncanonical Wnt5a enhances Wnt/β-catenin signaling during osteoblastogenesis.2014

    • Author(s)
      Okamoto, M., Udagawa, N., Yamashita, T., Nakamichi, Y., Uehara, S., Kato, H., Saito, N., Minami, Y., Takahashi, N., Kobayashi, Y.
    • Journal Title

      Sci Rep

      Volume: 4 Pages: 137-146

    • DOI

      10.1038/srep04493

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-23112007, KAKENHI-PROJECT-23593054, KAKENHI-PROJECT-23791668, KAKENHI-PROJECT-24240076, KAKENHI-PROJECT-24241045, KAKENHI-PROJECT-24390080, KAKENHI-PROJECT-24390417, KAKENHI-PROJECT-24592821, KAKENHI-PROJECT-24659833, KAKENHI-PROJECT-25221310, KAKENHI-PROJECT-25293423, KAKENHI-PROJECT-25462385, KAKENHI-PROJECT-25462904, KAKENHI-PROJECT-25462905, KAKENHI-PROJECT-25670792, KAKENHI-PROJECT-25670793, KAKENHI-PROJECT-26462825, KAKENHI-PROJECT-26670814
  • [Journal Article] Roles of Wnt signals in bone resorption during physiological and pathological states2013

    • Author(s)
      Maeda K et al.
    • Journal Title

      J. Mol. Med

      Volume: 91 Pages: 15-23

    • DOI

      10.1007/s00109-012-0974-0

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21390505, KAKENHI-PROJECT-23659972, KAKENHI-PROJECT-23791668, KAKENHI-PROJECT-24659833, KAKENHI-PROJECT-25221310
  • [Journal Article] Roles of cathelicidin-related antimicrobial peptide in murine osteoclastogenesis.2013

    • Author(s)
      Horibe K, Kobayashi Y, Takahashi N, Udagawa N(他4名)
    • Journal Title

      Immunology

      Volume: 140 Pages: 344-351

    • DOI

      10.1111/imm.12146

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-23593054, KAKENHI-PROJECT-24593112, KAKENHI-PROJECT-24593132, KAKENHI-PROJECT-24659833, KAKENHI-PROJECT-25221310, KAKENHI-PROJECT-25253097, KAKENHI-PROJECT-25462904, KAKENHI-PROJECT-25462905
  • [Journal Article] Mechanism of inhibitory action of Eldecalcitol, an active vitamin D analog, on bone resorption in vivo2013

    • Author(s)
      Takahashi N
    • Journal Title

      J Steroid Biochem Mol Biol

      Volume: 136(pii : S0960-0760(12)00243-9) Pages: 171-174

    • Data Source
      KAKENHI-PROJECT-24659833
  • [Journal Article] Osteoprotegerin-deficient male mice as a model for severe alveolar bone loss comparison with RANKL- overexpressing transgenic male mice.2013

    • Author(s)
      Koide M et al.
    • Journal Title

      Endocrinology

      Volume: 190 Pages: 773-782

    • DOI

      10.1210/en.2012-1928

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-21390505, KAKENHI-PROJECT-22390351, KAKENHI-PROJECT-23593027, KAKENHI-PROJECT-23593054, KAKENHI-PROJECT-23593074, KAKENHI-PROJECT-23659883, KAKENHI-PROJECT-23659972, KAKENHI-PROJECT-24390417, KAKENHI-PROJECT-24592786, KAKENHI-PROJECT-24592849, KAKENHI-PROJECT-24593112, KAKENHI-PROJECT-24593132, KAKENHI-PROJECT-24659833, KAKENHI-PROJECT-25221310, KAKENHI-PROJECT-25670793
  • [Journal Article] Mechanism of inhibitory action of Eldecalcitol, an active vitamin D analog, on bone resorption in vivo.2013

    • Author(s)
      Takahashi N
    • Journal Title

      J Steroid Biochem Mol Biol

      Volume: 136 Pages: 171-174

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25221310
  • [Journal Article] Tetracyclines convert the osteoclastic-differentiation pathway of progenitor cells to produce dendritic cell-like cells2012

    • Author(s)
      Kinugawa S et al.
    • Journal Title

      J Immunology

      Volume: 188 Pages: 1772-1781

    • DOI

      10.4049/jimmunol.1101174

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390505, KAKENHI-PROJECT-21390551, KAKENHI-PROJECT-22390351, KAKENHI-PROJECT-22659339, KAKENHI-PROJECT-22792102, KAKENHI-PROJECT-23659883, KAKENHI-PROJECT-23659972, KAKENHI-PROJECT-23792492, KAKENHI-PROJECT-24592786
  • [Journal Article] Regulation of Osteoclast Function2012

    • Author(s)
      Nakamura I, Takahashi N, Jimi E, Udagawa N, Suda T
    • Journal Title

      Mod Rheumatol

      Volume: 523 Pages: 167-177

    • DOI

      10.1007/s10165-011-0530-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390351, KAKENHI-PROJECT-24659833
  • [Journal Article] Wnt5a-Ror2 signaling between osteoblast-lineage cells and osteoclast precursors enhances osteoclastogenesis.2012

    • Author(s)
      Maeda, K., Kobayashi, Y., Udagawa, N., Uehara, S., Ishihara, A., Mizoguchi, T., Kikuchi, Y., Takada, I., Kato, S., Kani, S., Nishita, M., Marumo, K., Martin, T.J., Minami, Y., Takahashi, N.
    • Journal Title

      Nat Med.

      Volume: (印刷中) Pages: 405-12

    • DOI

      10.1038/nm.2653

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390080, KAKENHI-PROJECT-21390505, KAKENHI-PROJECT-21390551, KAKENHI-PUBLICLY-22021039, KAKENHI-PROJECT-22390351, KAKENHI-PROJECT-22659339, KAKENHI-PROJECT-22790291, KAKENHI-PLANNED-23112007, KAKENHI-PROJECT-23593054, KAKENHI-PROJECT-23650595, KAKENHI-PROJECT-23659972, KAKENHI-PROJECT-23791662, KAKENHI-PROJECT-23791668, KAKENHI-PROJECT-23792134, KAKENHI-PROJECT-24390417, KAKENHI-PROJECT-24659833
  • [Journal Article] Daily administration of eldecalcitol(ED-71), an active vitamin D analog, increases bone mineral density by suppressing RANKL expression in mouse trabecular bone2012

    • Author(s)
      Harada S et al.
    • Journal Title

      J. Bone Miner. Res.

      Volume: 27 Pages: 461-473

    • DOI

      10.1002/jbmr.555

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390505, KAKENHI-PROJECT-21390551, KAKENHI-PROJECT-22390351, KAKENHI-PROJECT-22659339, KAKENHI-PROJECT-22791804, KAKENHI-PROJECT-23659972, KAKENHI-PROJECT-23792135
  • [Journal Article] Bone Effects of vitamin D -Discrepancies between in vivo and in vitro studies -2012

    • Author(s)
      Suda T
    • Journal Title

      Arch Biochem Biophys

      Volume: 523 Pages: 22-29

    • DOI

      10.1016/j.abb.2011.11.011

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390351, KAKENHI-PROJECT-24659833
  • [Journal Article] c-Fms signaling mediates neurofibromatosis type-1 osteoclast gain-in-functions2012

    • Author(s)
      He Y, Rhodes SD, Chen S, Wu X, Yuan J, Yang X, Jiang L, Li X, Takahashi N, Xu M, Mohammad KS, Guise TA, Yang FC
    • Journal Title

      PLOS ONE

      Pages: 46900-46900

    • DOI

      10.1371/journal.pone.0046900

    • Data Source
      KAKENHI-PROJECT-24659833
  • [Journal Article] an active vitamin D analog, on bone resorption in vivo2012

    • Author(s)
      Takahashi N: Mechanism of inhibitory action of Eldecalcitol
    • Journal Title

      J Steroid Biochem Mol Biol

      Pages: 960-760

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390351
  • [Journal Article] New roles of osteoblasts involved in osteoclast differentiation2012

    • Author(s)
      Yamashita T, Takahashi N, Udagawa N
    • Journal Title

      World Journal of Orthopedics

      Volume: 3 Pages: 175-181

    • DOI

      10.5312/wjo.v3.i11.175

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390351, KAKENHI-PROJECT-23593054, KAKENHI-PROJECT-24592821, KAKENHI-PROJECT-24659833
  • [Journal Article] Mechanism of inhibitory action of Eldecalcitol, an active vitamin D analog, on bone resorption in vivo.2012

    • Author(s)
      Takahashi N
    • Journal Title

      J Steroid Biochem Mol Biol

      Volume: 12 Pages: 243-249

    • DOI

      10.1016/j.jsbmb.2012.11.010

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390351
  • [Journal Article] c-Fos plays an essential role in the up-regulation of RANK expression in osteoclast precursors within the bone microenvironment.2012

    • Author(s)
      Arai A et al.
    • Journal Title

      J Cell Sci. Feb;

      Volume: 125 Pages: 2910-17

    • DOI

      10.1242/jcs.099986

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390505, KAKENHI-PROJECT-22390351, KAKENHI-PROJECT-22791804, KAKENHI-PROJECT-23792135, KAKENHI-PROJECT-23792455, KAKENHI-PROJECT-24390417, KAKENHI-PROJECT-24659833
  • [Journal Article] Increased bone mass in mice after single injection of anti-receptor activator of nuclear factor-kB ligand-neutralizing antibody : evidence for bone anabolic effect of parathyroid hormone in mice with few osteoclasts2012

    • Author(s)
      Furuya Y, et al
    • Journal Title

      J Biol Chem

      Volume: 286 Pages: 37023-31

    • DOI

      10.1074/jbc.m111.246280

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390505, KAKENHI-PROJECT-22659339, KAKENHI-PROJECT-23659883
  • [Journal Article] Lineage-committed osteoclast precursors circulate in blood and settle down into bone2012

    • Author(s)
      Muto, A, Mizoguchi, T, Udagawa, N., Ito, S, Kawahara, I, Abiko, Y, Arai, A., Harada, S., Kobayashi, Y., Nakamichi, Y, Penninger, JM, Noguchi, T, Takahashi, N.
    • Journal Title

      J Bone MinerRes.Dec;

      Volume: 26 Pages: 2978-2990

    • DOI

      10.1002/jbmr.490

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390497, KAKENHI-PROJECT-21390498, KAKENHI-PROJECT-21390505, KAKENHI-PROJECT-21390550, KAKENHI-PROJECT-21390551, KAKENHI-PROJECT-21592615, KAKENHI-PROJECT-22390351, KAKENHI-PROJECT-22659339, KAKENHI-PROJECT-23593054, KAKENHI-PROJECT-23593074, KAKENHI-PROJECT-23792135, KAKENHI-PROJECT-23792455, KAKENHI-PROJECT-23792492
  • [Journal Article] Carbon nanotubes induce bone calcification by bidirectional interaction with osteoblasts.2012

    • Author(s)
      Shimizu M, Kobayashi Y, Mizoguchi T, Nakamura H, Kawahara I, Narita N, Usui Y, Aoki K, Hara K, Haniu H, Ogihara N, Ishigaki N, Nakamura K, Kato H, Kawakubo M, Dohi Y, Taruta S, Kim YA, Endo M, Ozawa H, Udagawa N, Takahashi N, Saito N
    • Journal Title

      細胞

      Volume: 24 Pages: 2176-2185

    • DOI

      10.1002/adma.201103832

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19002007, KAKENHI-PROJECT-21390505, KAKENHI-PROJECT-21390551, KAKENHI-PROJECT-22659339, KAKENHI-PROJECT-22791804, KAKENHI-PROJECT-23659972, KAKENHI-PROJECT-24659833
  • [Journal Article] Polarized osteoclasts put marks of tartrate-resistant acid phosphatase on dentin slices. A simple method for identifying polarized osteoclasts2012

    • Author(s)
      Nakayama T, et al
    • Journal Title

      Bone

      Volume: 49 Pages: 1331-1339

    • DOI

      10.1016/j.bone.2011.09.045

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390505, KAKENHI-PROJECT-21592378, KAKENHI-PROJECT-22390351, KAKENHI-PROJECT-22659339, KAKENHI-PROJECT-22791804, KAKENHI-PROJECT-23792134
  • [Journal Article] Regulation of Osteoclast Function2012

    • Author(s)
      Nakamura I, Takahashi N, Jimi E, Udagawa N, Suda T
    • Journal Title

      Mod Rheumatol

      Volume: 22(2) Pages: 167-177

    • NAID

      10030614771

    • URL

      http://www.ncbi.nlm.nih.gov/pubmed/21953286

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659339
  • [Journal Article] Spleen serves as a reservoir of osteoclast precursors through vitamin D-induced IL-34 expression in CSF-1op/op mice.2012

    • Author(s)
      Nakamichi Y et al.
    • Journal Title

      PNAS. Jun

      Volume: 109 Pages: 10006-1

    • DOI

      10.1073/pnas.1207361109

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390505, KAKENHI-PROJECT-22390351, KAKENHI-PROJECT-23659972, KAKENHI-PROJECT-23792135, KAKENHI-PROJECT-23792455, KAKENHI-PROJECT-24390417, KAKENHI-PROJECT-24659833
  • [Journal Article] c-Fos plays an essential role in the up-regulation of RANK expression in osteoclast precursors within the bone microenvironment2012

    • Author(s)
      Arai A, Mizoguchi T, Harada S, Kobayashi Y, Nakamichi Y, Yasuda H, Penninger JM, Yamada K, Udagawa N, Takahashi N
    • Journal Title

      J. Cell Sci

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390551
  • [Journal Article] Regulatory mechanism of osteoclastogenesis by RANKL and Wnt signals2011

    • Author(s)
      Takahashi N, Maeda K, Ishihara A, Uehara S, Kobayashi Y
    • Journal Title

      Front. Biosci

      Volume: 16 Pages: 21-30

    • URL

      http://dx.doi.org/10.2741/3673

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390551
  • [Journal Article] Polarized osteoclasts put marks of tartrate-resistant acid phosphatase on dentin slices-a simple method for identifying polarized osteoclasts2011

    • Author(s)
      Nakayama T, Mizoguchi T, Uehara S, Yamashita T, Kawahara I, Kobayashi Y, Moriyama Y, Kurihara S, Sahara N, Ozawa H, Udagawa N, Takahashi N
    • Journal Title

      Bone

      Volume: 49 Pages: 1331-1339

    • URL

      http://dx.doi.org/10.1016/j.bone.2011.09.045

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390551
  • [Journal Article] Polarized osteoclasts put marks of tartrate-resistant acid phosphatase on dentin slices-A simple method for identifying polarized osteoclasts-2011

    • Author(s)
      Nakayama T, Mizoguchi T, Uehara S, Yamashita T, Kawahara I, Kobayashi Y, Moriyama Y, Kurihara S, Sahara N, Ozawa H, Udagawa N, Takahashi N
    • Journal Title

      Bone

      Volume: 49(6) Pages: 1331-1339

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659339
  • [Journal Article] Hypergravity suppresses bone resorption in ovariectomized rats2011

    • Author(s)
      Ikawa T, et al
    • Journal Title

      Adv Space Res

      Volume: 47 Pages: 1214-1224

    • DOI

      10.1016/j.asr.2010.12.004

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390505, KAKENHI-PROJECT-22659339, KAKENHI-PROJECT-23593054, KAKENHI-PROJECT-23659883, KAKENHI-PROJECT-23792135
  • [Journal Article] Regulatory mechanism of osteoclastogenesis by RANKL and Wnt signals.2011

    • Author(s)
      Takahashi N, et.al.
    • Journal Title

      Front Biosci

      Volume: 16 Pages: 21-30

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390551
  • [Journal Article] Identification of osteoclasts in culture.2011

    • Author(s)
      Udagawa N, et al
    • Journal Title

      Methods in Molecular Biology

      Volume: 690 Pages: 273-284

    • DOI

      10.1007/978-1-60761-962-8_18

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390505, KAKENHI-PROJECT-21592378, KAKENHI-PROJECT-22390351, KAKENHI-PROJECT-22659339
  • [Journal Article] Regulatory mechanism of osteoclastogenesis by RANKL and Wnt signals2011

    • Author(s)
      Takahashi N, Maeda K, Ishihara A, Uehara S, Kobayashi Y
    • Journal Title

      Front Biosci

      Volume: 16 Pages: 21-30

    • URL

      http://www.ncbi.nlm.nih.gov/pubmed/21196156

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659339
  • [Journal Article] Regulatory mechanism of osteoclastogenesis by RANKL and Wnt signals.2011

    • Author(s)
      Takahashi N, Maeda K, Ishihara A, Uehara S, Kobayashi Y
    • Journal Title

      Front Biosci

      Volume: 16 Pages: 21-30

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390351
  • [Journal Article] Identification of cell cycle-arrested quiescent osteoclast precursors in vivo.2010

    • Author(s)
      Takahashi N, et al.
    • Journal Title

      Adv Exp Med Biol

      Volume: 658 Pages: 21-30

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659339
  • [Journal Article] Identification of cell cycle-arrested quiescent osteoclast precursors in vivo.2010

    • Author(s)
      Takahashi N, et al.
    • Journal Title

      Adv Exp Med Biol.

      Volume: 658 Pages: 21-30

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20200019
  • [Journal Article] Alisol-B, a novel phyto-steroid, suppresses the RANKL-induced osteoclast formation and prevents bone loss in mice2010

    • Author(s)
      Lee JW, Kobayashi Y, Nakamichi Y, Udagawa N, Takahashi N, Im NK, Seo HJ, Jeon WB, Yonezawa T, Cha BY, Woo JT.
    • Journal Title

      Biochem. Pharmacol

      Volume: 80 Pages: 352-361

    • URL

      http://dx.doi.org/10.1016/j.bcp.2010.04.014

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390551
  • [Journal Article] Function of OPG as a traffic regulator for RANKL is crucial for controlled osteoclastogenesis.2010

    • Author(s)
      Aoki S, Nakamichi Y, Ninomiya T, Takahashi N, Udagawa N
    • Journal Title

      J Bone Miner Res. 25

      Pages: 1907-1921

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20200019
  • [Journal Article] Identification of cell cycle-arrested quiescent osteoclast precursors in vivo.2010

    • Author(s)
      Takahashi N, Muto A, Arai A, Mizoguchi T
    • Journal Title

      Adv Exp Med Biol

      Volume: 658 Pages: 21-30

    • DOI

      10.1007/978-1-4419-1050-9_3

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390351
  • [Journal Article] Identification of cell cycle-arrested quiescent osteoclast precursors in vivo2010

    • Author(s)
      Takahashi N, et al.
    • Journal Title

      Adv Exp Med Biol

      Volume: 658 Pages: 21-30

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21592378
  • [Journal Article] Osteoclastic bone resorption induced by innate immune responses.2010

    • Author(s)
      Koide M, Kinugawa S, Takahashi N, Udagawa N.
    • Journal Title

      Periodontol 2000. 54

      Pages: 235-246

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20200019
  • [Journal Article] Identification of cell cycle-arrested quiescent osteoclast precursors in vivo.2010

    • Author(s)
      Takahashi N, Mizoguchi T
    • Journal Title

      Adv Exp Med Biol. 658

      Pages: 21-30

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20200019
  • [Journal Article] Identification of cell cycle-arrested quiescent osteoclast precursors in vivo2010

    • Author(s)
      Naoyuki Takahashi
    • Journal Title

      Adv Exp Med Biol. 658

      Pages: 21-30

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20200019
  • [Journal Article] Osteoclastic bone resorption induced by innate immune responses2010

    • Author(s)
      Koide M, Kinugawa S, Takahashi N, UdagawaN.
    • Journal Title

      Periodontol 2000

      Volume: 54 Pages: 235-246

    • DOI

      10.1111/j.1600-0757.2010.00355.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390351, KAKENHI-PROJECT-22792102
  • [Journal Article] Identification of cell cycle-arrested quiescent osteoclast precursors in vivo.2009

    • Author(s)
      Mizoguchi T, Muto A, Udagawa N, Arai A, Yamashita T, Hosoya A, Ninomiya T, Nakamura H, Yamamoto Y, Kinugawa S, Nakamura M, Nakamichi Y, Kobayashi Y, Nagasawa S, Oda K, Tanaka H, Tagaya M, Penninger JM, Ito M, Takahashi N
    • Journal Title

      J Cell Biol 184

      Pages: 541-554

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592163
  • [Journal Article] Docetaxel inhibits bone resorption through suppression of osteoclast formation and function in different manners.2009

    • Author(s)
      Takahashi M, Mizoguchi T, Uehara S, Nakamichi Y, Yang S, Naramoto H, Yamashita T, Kobayashi Y, Yamaoka M, Furusawa K, Udagawa N, Uematsu T, Takahashi N
    • Journal Title

      J Bone Miner Metab 27

      Pages: 24-35

    • NAID

      10025336084

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592163
  • [Journal Article] Diphenylhydantoin inhibits osteoclast differentiation and function through suppression of NFATc1 signaling2009

    • Author(s)
      Koide M, Kinugawa S, Ninomiya T, Mizoguchi T, Yamashita T, Maeda K, Yasuda H, Kobayashi Y, Nakamura H, Takahashi N, Udagawa N
    • Journal Title

      Journal of Bone and Mineral Research

      Volume: 24(8) Pages: 1469-1480

    • DOI

      10.1359/jbmr.090302

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21592378
  • [Journal Article] Multiwalled carbon nanotubes specifically inhibit osteoclast differentiation and function.2009

    • Author(s)
      Narita N, Nakamura H, Mizoguchi T, Ozawa H, Udagawa N, Takahashi N
    • Journal Title

      Nano Lett. 9

      Pages: 1406-1413

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20200019
  • [Journal Article] Docetaxel inhibits bone resorption through suppression of osteoclast formation and function in different manners.2009

    • Author(s)
      Takahashi M, et al.
    • Journal Title

      J Bone Miner Metab 27

      Pages: 24-35

    • NAID

      10025336084

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592163
  • [Journal Article] Docetaxel inhibits bone resorption through suppression of osteoclast formation and function different manners.2009

    • Author(s)
      Takahashi M, Mizoguchi T, Nakamichi Y, Yamashita T, Udagawa N, Takahashi N
    • Journal Title

      J. Bone Miner. Metab. 27

      Pages: 24-35

    • NAID

      10025336084

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20200019
  • [Journal Article] Docetaxel inhibits bone resorption through suppression of osteoclast formation and function in different manners2009

    • Author(s)
      Takahashi M, et al.
    • Journal Title

      J Bone Miner Metab 27

      Pages: 24-35

    • NAID

      10025336084

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21592378
  • [Journal Article] Formation of bone -like mineralized matrix by periodontal ligament cells in vivo : a morphological study in rats.2009

    • Author(s)
      Hiraga T, Ninomiya T, Hosoya A, Takahashi M, Nakamura H
    • Journal Title

      J Bone Miner Metab. 27

      Pages: 149-157

    • NAID

      10025336621

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20200019
  • [Journal Article] Identification of cell cycle-arrested quiescent osteoclast precursors in vivo2009

    • Author(s)
      Mizoguchi T, Muto A, Udagawa N, Arai A, Yamashita T, Hosoya A, Ninomiya T, Nakamura H, Yamamoto Y, Kinugawa S, Nakamura M, Nakamichi Y, Kobayashi Y, Nagasawa S, Oda K, Tanaka H, Tagaya M, Penninger JM, Ito M, Takahashi N.
    • Journal Title

      Journal of Cell Biology

      Volume: 184(4) Pages: 541-54

    • DOI

      10.1083/jcb.200806139

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390505, KAKENHI-PROJECT-21592378
  • [Journal Article] Action of RANKL and OPG for osteoclastogenesis2009

    • Author(s)
      Kobayashi Y, Udagawa N, Takahashi N
    • Journal Title

      Crit. Rev. Eukaryot. Gene Expr

      Volume: 19 Pages: 61-72

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390551
  • [Journal Article] Diphenylhydantoin inhibits osteoclast differentiation and function through suppression of NFATc1 signaling.2009

    • Author(s)
      Koide M, Nynomiya T, Mizoguchi T, Yamashita T, Nakamura H, Takahashi N, Udagawa N
    • Journal Title

      J Bone Miner Res. 24

      Pages: 1469-1480

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20200019
  • [Journal Article] The relationship between calcium accumulation in osteoclast mitochondrial granules and bone resorption.2009

    • Author(s)
      Kawahara I, Koide M, Tadokoro O, Udagawa N, Nakamura H, Takahashi N, Ozawa H
    • Journal Title

      Bone. 45

      Pages: 980-986

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20200019
  • [Journal Article] Identification of cell cycle-arrested quiescent osteoclast precursors in vivo.2009

    • Author(s)
      Mizoguchi T, Udagawa N, Yamashita T, Hosoya A, Ninomiya T, Nakamichi Y, Takahashi N
    • Journal Title

      J Cell Biol. 184

      Pages: 541-554

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20200019
  • [Journal Article] Docetaxel inhibits bone resorption through suppression of osteoclast for mation and function in different manners2008

    • Author(s)
      Takahashi M, et. al.
    • Journal Title

      J Bone Miner Metab 27(In press)

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17592119
  • [Journal Article] MKK6-p38 MAPK signaling pathway enhances survival but not bone-resorbing activity of osteoclasts.2008

    • Author(s)
      Yamashita T, Kobayashi Y, Mizoguchi T, Yamaki M, Miura T, Tanaka S, Udagawa N, Takahashi N
    • Journal Title

      Biochem Biophys Res Commun 365

      Pages: 252-257

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592163
  • [Journal Article] Current paradigms of osteoblast-osteoclast interactions and bacterial pathogen-induced bone resorption.2008

    • Author(s)
      Takahashi N, et. al.
    • Journal Title

      Periodontal Medicine and Systems Biology, Blackwell Publishing, Oxford (In press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390495
  • [Journal Article] Docetaxel inhibits bone resorption through suppression of osteoclast formation and function in different manners.2008

    • Author(s)
      Takahashi M, Takahashi M, Mizoguchi T, Uehara S, Nakamichi Y, Yang S, Naramoto H, Yamashita T, Kobayashi Y, Furusawa K, Yamaoka M, Udagawa N, Uematsu T, Takahashi N
    • Journal Title

      J Bone Miner Metab (in press)

    • NAID

      10025336084

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17592119
  • [Journal Article] Docetaxel inhibits bone resorption through suppression of osteoclast formation and function in different manners2008

    • Author(s)
      Takahashi M, et. al.
    • Journal Title

      J Bone Miner Metab (In press)

    • NAID

      10025336084

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390495
  • [Journal Article] Osteoclast generation2008

    • Author(s)
      Takahashi N, et. al.
    • Journal Title

      Principles of bone biology Third edition, Academic Press, San Diego (In press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390495
  • [Journal Article] Regulation of osteoclast polarization2007

    • Author(s)
      Takahashi N, et. al.
    • Journal Title

      Odontology 95

      Pages: 1-9

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390495
  • [Journal Article] Generation of osteoclasts in vitro, and assay of osteoclast activity2007

    • Author(s)
      Naoyuki Takahashi
    • Journal Title

      Methods. Mol Med 135

      Pages: 285-301

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390557
  • [Journal Article] 破骨細胞の形成部位を決める破骨細胞ニッチ2007

    • Author(s)
      高橋直之
    • Journal Title

      医学の歩み 221

      Pages: 285-301

    • Data Source
      KAKENHI-PROJECT-18390495
  • [Journal Article] Generation of osteoclasts in vitro,and assay of osteoclast activity2007

    • Author(s)
      Takahashi N, et. al.
    • Journal Title

      Methods Mol Med 135

      Pages: 285-301

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390495
  • [Journal Article] Generation of osteoclasts in vitro, and assay of osteoclast activity2007

    • Author(s)
      Takahashi N, et. al.
    • Journal Title

      Methods Mol Med 135

      Pages: 285-301

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592163
  • [Journal Article] Generation of osteoclasts in vitro, and assay of osteoclast activity2007

    • Author(s)
      Takahashi N
    • Journal Title

      Methods Mol Med 135

      Pages: 285-301

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390495
  • [Journal Article] Regulation of osteoclast polarization2007

    • Author(s)
      Takahashi N
    • Journal Title

      Odontology 95

      Pages: 252-257

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390495
  • [Journal Article] Regulation of osteoclast polarization.2007

    • Author(s)
      Takahashi N, et. al.
    • Journal Title

      Odontology 95

      Pages: 1-9

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390495
  • [Journal Article] Generation of osteoclasts in vitro,and assay of osteoclast activity2007

    • Author(s)
      Naoyuki Takahashi, et. al.
    • Journal Title

      Methods.Mol Med 135

      Pages: 285-301

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390557
  • [Journal Article] Generation of osteoclasts in vitro, and assay of osteoclast activity.2007

    • Author(s)
      Takahashi N, et. al.
    • Journal Title

      Methods Mol Med 135

      Pages: 285-301

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390495
  • [Journal Article] Synergistic effects of FGF-2 with insulin or IGF-1 on the proliferation of human auricular chondrocytes.2005

    • Author(s)
      Takahashi T. et al.
    • Journal Title

      Cell Transplant 14・9

      Pages: 683-693

    • Data Source
      KAKENHI-PROJECT-16659506
  • [Journal Article] Spleen serves as a reservoir of osteoclast precursors through vitamin D-induced IL-34 expression in CSF-1^<op/op> mice

    • Author(s)
      Nakamichi Y, Mizoguchi T, Arai A, Kobayashi Y, Sato M, Penninger JM, Yasuda H, Kato S, DeLuca HF, Suda T, Udagawa N, Takahashi N
    • Journal Title

      Proc Natl Acad Sci UAS

      Volume: (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659339
  • [Journal Article] Regulatory mechanism of osteoclastogenesis by Wnt signaling.

    • Author(s)
      Kobayashi Y, Maeda K, Uehara S, Yamashita T, Takahashi N
    • Journal Title

      Inflammation and Regeneration

      Volume: (In press)

    • NAID

      130004943807

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390351
  • [Journal Article] Regulation of osteoclast polarization.

    • Author(s)
      Takahashi N. et al.
    • Journal Title

      Odontology (In press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591924
  • [Journal Article] c-Fos plays an essential role in the up-regulation of RANK expression in osteoclast precursors within the bone microenvironment

    • Author(s)
      Arai A, Mizoguchi T, Harada S, Kobayashi Y, Nakamichi Y, Yasuda H, Penninger JM, Yamada K, Udagawa N, Takahashi N
    • Journal Title

      J Cell Science

      Volume: (In press)

    • URL

      http://www.ncbi.nlm.nih.gov/pubmed/22454522

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659339
  • [Journal Article] Regulatory mechanism of osteoclastogenesis by Wnt signaling

    • Author(s)
      Kobayashi Y, Maeda K, Uehara S, Yamashita T, Takahashi N
    • Journal Title

      Inflammation and Regeneration

      Volume: (In press)

    • NAID

      130004943807

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659339
  • [Journal Article] Regulation of osteoclast polarization

    • Author(s)
      Takahashi N. et al.
    • Journal Title

      Odentology (in press)

    • Data Source
      KAKENHI-PROJECT-17591924
  • [Journal Article] Bone Effects of vitamin D-Discrepancies between in vivo and in vitro studies-

    • Author(s)
      Suda T, Takahashi F, Takahashi N
    • Journal Title

      Arch Biochem Biophys

      Volume: (In press)

    • URL

      http://www.ncbi.nlm.nih.gov/pubmed/22107950

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659339
  • [Presentation] Wnt/β-cateninシグナルの制御系をモニターするSost-Greenレポーターマウスの作出2019

    • Author(s)
      山下照仁,小出雅則,堀部寛治,上原俊介,宇田川信之,高橋直之,中村浩彰,小林泰浩
    • Organizer
      第88回松本歯科大学学会総会
    • Data Source
      KAKENHI-PROJECT-18K09531
  • [Presentation] 破骨細胞生物学の歴史:RANKL発見までを振り返る。2019

    • Author(s)
      高橋直之
    • Organizer
      松本歯科大学総合歯科医学研究所開設30年記念講演会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H05144
  • [Presentation] Osteoclasts promote trabecular bone formation through the suppression of sclerostin expression2019

    • Author(s)
      Masanori Koide, Yasuhiro Kobayashi, Teruhito Yamashita, Kohei Murakami, Shunsuke Uehara, Hisataka Yasuda, Naoyuki Takahashi, Nobuyuki Udagawa
    • Organizer
      The American Society for Bone and Mineral Research (ASBMR) 2019 Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K09531
  • [Presentation] なぜ共存培養だったのか.2018

    • Author(s)
      高橋直之
    • Organizer
      2018 Dentistry Quo Vadis?
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H05144
  • [Presentation] 破骨細胞研究の歴史を振り返る2018

    • Author(s)
      高橋直之
    • Organizer
      第36回日本骨代謝学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H05144
  • [Presentation] How does vitamin D regulate osteoclastic bone resorption?2018

    • Author(s)
      Naoyuki Takahashi
    • Organizer
      17th Annual Meeting of Korean Association of Oral Science
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H05144
  • [Presentation] Progress of osteoclast biology2017

    • Author(s)
      高橋直之
    • Organizer
      第2回日本骨免疫学会ウィンターセミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H05144
  • [Presentation] 須田先生と骨代謝研究2017

    • Author(s)
      高橋直之
    • Organizer
      第35回日本骨代謝学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H05144
  • [Presentation] デノスマブが骨代謝研究に与えた影響2017

    • Author(s)
      高橋直之
    • Organizer
      2017年Dentistry, Quo Vadis?
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H05144
  • [Presentation] Wnt5a-Ror2シグナルにより活性化されるRor-Pkn3経路はc-Srcを介して骨吸収を調節する。2016

    • Author(s)
      上原俊介、山下照仁、中村 貴、加藤茂明、宇田川信之、高橋直之、小林泰浩
    • Organizer
      第34回日本骨代謝学会
    • Place of Presentation
      大阪国際会議場、大阪市北区中之島
    • Year and Date
      2016-07-21
    • Data Source
      KAKENHI-PROJECT-16H05144
  • [Presentation] いまデンティストリーに骨代謝がなぜ必要か2015

    • Author(s)
      高橋直之
    • Organizer
      Dentistry, Quo Vadis?
    • Place of Presentation
      星陵会館 (東京都千代田区)
    • Year and Date
      2015-12-06
    • Invited
    • Data Source
      KAKENHI-PROJECT-25221310
  • [Presentation] 破骨細胞の研究からわかってきたこと2015

    • Author(s)
      高橋直之
    • Organizer
      歯科基礎平成27年度社員総会
    • Place of Presentation
      日本歯科大学富士見ホール(東京都千代田区)
    • Year and Date
      2015-04-25
    • Invited
    • Data Source
      KAKENHI-PROJECT-26670814
  • [Presentation] 破骨細胞研究から学んだこと2015

    • Author(s)
      高橋直之
    • Organizer
      平成27年度大阪歯科学会大会
    • Place of Presentation
      大阪歯科大学創立100周年記念館 (大阪市中央区)
    • Year and Date
      2015-11-21
    • Invited
    • Data Source
      KAKENHI-PROJECT-25221310
  • [Presentation] 破骨細胞の研究からわかってきたこと2015

    • Author(s)
      高橋直之
    • Organizer
      歯科基礎平成27年度社員総会 生化学分野 分科会講演会
    • Place of Presentation
      日本歯科大学富士見ホール (東京都千代田区)
    • Year and Date
      2015-04-25
    • Invited
    • Data Source
      KAKENHI-PROJECT-25221310
  • [Presentation] アルクチゲニンの破骨細胞分化抑制メカニズム2014

    • Author(s)
      山下照仁,小林泰浩,上原俊介,宇田川信之,李峰,門田重利,江角浩安,高橋直之
    • Organizer
      第56回歯科基礎医学会学術大会・総会
    • Place of Presentation
      福岡国際会議場(福岡市)
    • Year and Date
      2014-09-26
    • Data Source
      KAKENHI-PROJECT-24592821
  • [Presentation] 破骨細胞の分化と機能を調節するRANKL-RANKシグナル2014

    • Author(s)
      高橋直之
    • Organizer
      第一回日本骨免疫会議
    • Place of Presentation
      万国津梁館 名護市喜瀬
    • Year and Date
      2014-07-05
    • Invited
    • Data Source
      KAKENHI-PROJECT-26670814
  • [Presentation] 抗炎症作用を持つアルクチゲニンの破骨細胞抑制メカニズム2014

    • Author(s)
      山下照仁,小林泰浩,上原俊介,宇田川信之,李峰,門田重利,江角浩安,高橋直之
    • Organizer
      第1回日本骨免疫会議
    • Place of Presentation
      万国津梁館(名護市)
    • Year and Date
      2014-07-04
    • Data Source
      KAKENHI-PROJECT-24592821
  • [Presentation] 破骨細胞はどのような機序で骨組織に誘導される2014

    • Author(s)
      高橋直之
    • Organizer
      第45回京都骨・カルシウム代謝研究会
    • Place of Presentation
      ホテルグランヴィア京都、京都市 下京区
    • Year and Date
      2014-11-04
    • Invited
    • Data Source
      KAKENHI-PROJECT-25221310
  • [Presentation] 歯周病において破骨細胞はどのように誘導されるか2014

    • Author(s)
      高橋直之
    • Organizer
      第57回春季日本歯周病学会
    • Place of Presentation
      長良川国際会議場 岐阜市長良福光
    • Year and Date
      2014-05-23
    • Invited
    • Data Source
      KAKENHI-PROJECT-26670814
  • [Presentation] 歯周病において破骨細胞はどのように誘導されるか2014

    • Author(s)
      高橋直之
    • Organizer
      第57回春季日本歯周病学会
    • Place of Presentation
      長良川国際会議場  岐阜市長良福光
    • Year and Date
      2014-05-23
    • Invited
    • Data Source
      KAKENHI-PROJECT-25221310
  • [Presentation] Arctigenin Inhibits Osteoclastogenesis by Suppressing Both Calcineurin-Dependent and Osteoblastic Cell-Dependent NFATc1 Pathways2014

    • Author(s)
      Yamashita T,Uehara S,Udagawa N,Li F,Kadota S,Esumi H,Kobayashi Y,Takahashi N
    • Organizer
      ASBMR 2014 Annual Meeting
    • Place of Presentation
      George R. Brown Convention Center (Houston, USA)
    • Year and Date
      2014-09-13
    • Data Source
      KAKENHI-PROJECT-24592821
  • [Presentation] 歯周病において破骨細胞はどのように誘導されるか2014

    • Author(s)
      高橋直之
    • Organizer
      第57回春季日本歯周病学会
    • Place of Presentation
      岐阜
    • Year and Date
      2014-05-23
    • Data Source
      KAKENHI-PROJECT-24659833
  • [Presentation] 破骨細胞はどのような機序で骨組織に誘導されるか2014

    • Author(s)
      高橋直之
    • Organizer
      第45回京都骨・カルシウム代謝研究会
    • Place of Presentation
      ホテルグランヴィア京都、京都市下京区
    • Year and Date
      2014-11-14
    • Invited
    • Data Source
      KAKENHI-PROJECT-26670814
  • [Presentation] 破骨細胞の分化と機能を調節するRANKL-RANKシグナ2014

    • Author(s)
      高橋直之
    • Organizer
      第一回日本骨免疫会議
    • Place of Presentation
      万国津梁館  名護市喜瀬
    • Year and Date
      2014-07-05
    • Invited
    • Data Source
      KAKENHI-PROJECT-25221310
  • [Presentation] 破骨細胞前駆細胞を制御する骨芽細胞の新しい役割2013

    • Author(s)
      高橋直之
    • Organizer
      第15回骨とリウマチ研究会
    • Place of Presentation
      東京
    • Year and Date
      2013-01-31
    • Data Source
      KAKENHI-PROJECT-24659833
  • [Presentation] Mechanism of anti-bone resorptive action of eldecalcitol2013

    • Author(s)
      Naoyuki Takahashi
    • Organizer
      Advisory meeting of active vitamin D
    • Place of Presentation
      Kobe
    • Year and Date
      2013-05-28
    • Data Source
      KAKENHI-PROJECT-24659833
  • [Presentation] 破骨細胞の分化と機能を調節するRANKL-RANKシグナル2013

    • Author(s)
      高橋直之
    • Organizer
      城北骨代謝フォーラム東京
    • Place of Presentation
      東京
    • Year and Date
      2013-10-29
    • Data Source
      KAKENHI-PROJECT-24659833
  • [Presentation] 破骨細胞の分化と機能を調節するRANKL-RANK シグナル2013

    • Author(s)
      高橋直之
    • Organizer
      城北骨代謝フォーラム
    • Place of Presentation
      ホテルグランドシティー 豊島区東池袋
    • Year and Date
      2013-10-29
    • Invited
    • Data Source
      KAKENHI-PROJECT-25221310
  • [Presentation] 骨芽細胞と破骨細胞、そして力の関係2013

    • Author(s)
      高橋直之
    • Organizer
      Dentistry、Quo Vadis?
    • Place of Presentation
      星陵会館 千代田区永田町
    • Year and Date
      2013-12-07
    • Invited
    • Data Source
      KAKENHI-PROJECT-25221310
  • [Presentation] 破骨細胞の分化と機能の調節機構2013

    • Author(s)
      高橋直之
    • Organizer
      第86回日本整形外科学会学術総会
    • Place of Presentation
      広島
    • Year and Date
      2013-05-23
    • Data Source
      KAKENHI-PROJECT-24659833
  • [Presentation] Wnt5a enhances Wnt/beta-catenin signaling through the up-regulation of Lrp5/6 during osteogenesis2013

    • Author(s)
      Okamoto M, UdagawaN, Yamashita T, Uehara S, Kato H, Saito N, Minami Y, Takahashi N, Kobayashi Y
    • Organizer
      2013 米国骨代謝学会
    • Place of Presentation
      Baltimore Convention Center, USA
    • Data Source
      KAKENHI-PROJECT-25293423
  • [Presentation] チタンインプラント埋入における生体側のイベントII2013

    • Author(s)
      高橋直之
    • Organizer
      Dentistry Quo Vadis?
    • Place of Presentation
      東京
    • Year and Date
      2013-12-08
    • Data Source
      KAKENHI-PROJECT-24659833
  • [Presentation] インプラントはOsseointegrationをどのように獲得するか2013

    • Author(s)
      高橋直之
    • Organizer
      松本歯科大学インプラントカンファレンス
    • Place of Presentation
      塩尻
    • Year and Date
      2013-06-10
    • Data Source
      KAKENHI-PROJECT-24659833
  • [Presentation] TRAP marks as vestiges of polarized osteoclasts2013

    • Author(s)
      Naoyuki Takahashi
    • Organizer
      6^<th> International symposium on the biology of tartrate resistant acid phosphatase
    • Place of Presentation
      Kobe
    • Year and Date
      2013-05-27
    • Data Source
      KAKENHI-PROJECT-24659833
  • [Presentation] 骨芽細胞と破骨細胞、そして力の関係2013

    • Author(s)
      高橋直之
    • Organizer
      Dentistry、Quo Vadis?
    • Place of Presentation
      東京
    • Year and Date
      2013-12-07
    • Data Source
      KAKENHI-PROJECT-24659833
  • [Presentation] 骨吸収を調節するWntシグナル2013

    • Author(s)
      高橋直之
    • Organizer
      第4回彩の国骨フォーラム
    • Place of Presentation
      埼玉
    • Year and Date
      2013-02-08
    • Data Source
      KAKENHI-PROJECT-24659833
  • [Presentation] Mechanism of inhibitory action of eldecalcitol, an active vitamin D analog, on bone resorption in vivo2012

    • Author(s)
      Naoyuki Takahashi
    • Organizer
      5^<th> Workshop on Vitamin D
    • Place of Presentation
      Huston
    • Year and Date
      2012-06-22
    • Data Source
      KAKENHI-PROJECT-24659833
  • [Presentation] チタンインプラント埋入における生体側のイベントII2012

    • Author(s)
      高橋直之
    • Place of Presentation
      東京
    • Year and Date
      2012-12-08
    • Data Source
      KAKENHI-PROJECT-22390351
  • [Presentation] 骨吸収の調節機構2012

    • Author(s)
      高橋直之
    • Organizer
      鹿児島大学歯学部セミナー
    • Place of Presentation
      鹿児島
    • Year and Date
      2012-01-16
    • Data Source
      KAKENHI-PROJECT-22390351
  • [Presentation] Mechanism of inhibitory action of eldecalcitol an active vitamin D analog, on bone resorption in vivo.2012

    • Author(s)
      Naoyuki Takahashi
    • Organizer
      Invited lecture, 5th Workshop on Vitamin D
    • Place of Presentation
      Huston
    • Year and Date
      2012-06-22
    • Data Source
      KAKENHI-PROJECT-22390351
  • [Presentation] Osteoclast precursors in vivo2012

    • Author(s)
      Naoyuki Takahashi
    • Organizer
      東京医科歯科大学GCOE
    • Place of Presentation
      東京医科歯科大学
    • Year and Date
      2012-01-24
    • Data Source
      KAKENHI-PROJECT-22659339
  • [Presentation] Osteoclast precursors in vivo2012

    • Author(s)
      Naoyuki Takahashi
    • Organizer
      東京医科歯科大学 GCOE
    • Year and Date
      2012-01-24
    • Data Source
      KAKENHI-PROJECT-22390351
  • [Presentation] 破骨細胞の分化を調節する骨芽 細胞の新しい役割2012

    • Author(s)
      高橋直之
    • Organizer
      創価大学セミナー
    • Place of Presentation
      東京
    • Year and Date
      2012-11-16
    • Data Source
      KAKENHI-PROJECT-22390351
  • [Presentation] 破骨細胞はどのように骨を認識し 極性化するか日本歯科理工学会・2012

    • Author(s)
      高橋直之
    • Organizer
      中部支部夏季セミナー
    • Place of Presentation
      妙高高原
    • Year and Date
      2012-08-23
    • Data Source
      KAKENHI-PROJECT-22390351
  • [Presentation] 破骨細胞の分化と機能の調節機構2012

    • Author(s)
      高橋直之
    • Organizer
      九州大学大学院セミナー
    • Place of Presentation
      福岡
    • Year and Date
      2012-10-25
    • Data Source
      KAKENHI-PROJECT-22390351
  • [Presentation] 破骨細胞の分化を調節する骨芽細胞の新しい役割2012

    • Author(s)
      高橋直之
    • Organizer
      創価大学セミナー
    • Place of Presentation
      東京
    • Year and Date
      2012-11-16
    • Data Source
      KAKENHI-PROJECT-24659833
  • [Presentation] 破骨細胞はどのように骨を認識し極性化するか2012

    • Author(s)
      高橋直之
    • Organizer
      日本歯科理工学会・中部支部夏季セミナー
    • Place of Presentation
      妙高高原
    • Year and Date
      2012-08-23
    • Data Source
      KAKENHI-PROJECT-24659833
  • [Presentation] 骨吸収を調節する骨芽細胞の新しい役割2011

    • Author(s)
      高橋直之
    • Organizer
      第26回長崎骨粗鬆症研究会
    • Place of Presentation
      長崎県医師会館(長崎)(招待講演)
    • Year and Date
      2011-11-30
    • Data Source
      KAKENHI-PROJECT-22659339
  • [Presentation] 分子メカニズムを知る意味とは2011

    • Author(s)
      高橋直之
    • Organizer
      Dentistry Quo Vadis
    • Place of Presentation
      東京
    • Year and Date
      2011-12-11
    • Data Source
      KAKENHI-PROJECT-22390351
  • [Presentation] チタンインプラント埋入における生 体側のイベント2011

    • Author(s)
      高橋直之
    • Organizer
      Dentistry Quo Vadis
    • Place of Presentation
      東京
    • Year and Date
      2011-12-10
    • Data Source
      KAKENHI-PROJECT-22390351
  • [Presentation] 骨吸収を調節する骨芽細胞の新しい役割(招待講演)2011

    • Author(s)
      高橋直之
    • Organizer
      第26回長崎骨粗鬆症研究会
    • Year and Date
      2011-11-30
    • Data Source
      KAKENHI-PROJECT-22659339
  • [Presentation] Quiescent Osteoclast Precursors2011

    • Author(s)
      Naoyuki Takahashi
    • Organizer
      2nd Asia-Pacific Osteoporosis and Bone Meeting
    • Place of Presentation
      Gold Coast Convention center Gold Coast, Autraria(招待講演)
    • Year and Date
      2011-09-07
    • Data Source
      KAKENHI-PROJECT-22659339
  • [Presentation] 骨吸収を調節する骨芽細胞の新しい役割2011

    • Author(s)
      高橋直之
    • Organizer
      第26回長崎骨粗鬆症研究会
    • Place of Presentation
      長崎県医師会館(長崎)(招待講演)
    • Year and Date
      2011-11-30
    • Data Source
      KAKENHI-PROJECT-22390351
  • [Presentation] 分子メカニズムを知る意味とは(招待講演)2011

    • Author(s)
      高橋直之
    • Organizer
      Dentistry Quo Vadis
    • Place of Presentation
      東京
    • Year and Date
      2011-12-11
    • Data Source
      KAKENHI-PROJECT-22659339
  • [Presentation] 骨吸収を調節する骨芽細胞の新 しい役割2011

    • Author(s)
      高橋直之
    • Organizer
      第26回長崎骨粗鬆症研究会
    • Year and Date
      2011-11-30
    • Data Source
      KAKENHI-PROJECT-22390351
  • [Presentation] チタンインプラント埋入における生体側のイベント(招待講演)2011

    • Author(s)
      高橋直之
    • Organizer
      Dentistry Quo Vadis
    • Place of Presentation
      東京
    • Year and Date
      2011-12-10
    • Data Source
      KAKENHI-PROJECT-22659339
  • [Presentation] Quiescent Osteoclast Precursors2011

    • Author(s)
      Naoyuki Takahashi
    • Organizer
      Invited lecture 2^<nd> Asia-Pacific Osteoporosis and Bone Meeting
    • Year and Date
      2011-09-07
    • Data Source
      KAKENHI-PROJECT-22659339
  • [Presentation] Quiescent Osteoclast Precursors.2011

    • Author(s)
      Naoyuki Takahashi
    • Organizer
      Invited lecture 2nd Asia-Pacific Osteoporosis and Bone Meeting
    • Year and Date
      2011-09-07
    • Data Source
      KAKENHI-PROJECT-22390351
  • [Presentation] 破骨細胞を制御する骨芽細胞の新しい役割(招待講演)2011

    • Author(s)
      高橋直之
    • Organizer
      九州大学大学院講義
    • Place of Presentation
      福岡
    • Year and Date
      2011-05-12
    • Data Source
      KAKENHI-PROJECT-22659339
  • [Presentation] 破骨細胞を制御する骨芽細胞の新しい役割2011

    • Author(s)
      高橋直之
    • Organizer
      九州大学大学院講義
    • Place of Presentation
      福岡
    • Year and Date
      2011-05-12
    • Data Source
      KAKENHI-PROJECT-22390351
  • [Presentation] 骨吸収の調節機構2011

    • Author(s)
      高橋直之
    • Organizer
      鹿児島大学歯学部セミナー
    • Year and Date
      2011-01-16
    • Data Source
      KAKENHI-PROJECT-22659339
  • [Presentation] Quiescent Osteoclast Precursors2011

    • Author(s)
      Naoyuki Takahashi
    • Organizer
      2nd Asia-Pacific Osteoporosis and Bone Meeting
    • Place of Presentation
      Gold Coast Convention Center Gold Coast, Autraria(招待講演)
    • Year and Date
      2011-09-07
    • Data Source
      KAKENHI-PROJECT-22390351
  • [Presentation] Characteristics of osteoclast precursors in vivo.2010

    • Author(s)
      Naoyuki Takahashi
    • Organizer
      7th Meeting of Bone Biology Forum
    • Place of Presentation
      Susono,Japan
    • Year and Date
      2010-08-20
    • Data Source
      KAKENHI-PROJECT-22390351
  • [Presentation] 骨吸収を調節するRANKL-RANK系2010

    • Author(s)
      高橋直之
    • Organizer
      第28回日本骨代謝会学術集会,ランチョンセミナー
    • Place of Presentation
      京王プラザホテル、東京
    • Year and Date
      2010-07-21
    • Data Source
      KAKENHI-PROJECT-22390351
  • [Presentation] 破骨細胞形成を調節する骨芽細 胞の新しい役割2010

    • Author(s)
      高橋直之
    • Organizer
      第10回徳島 Bone Forum
    • Place of Presentation
      徳島
    • Year and Date
      2010-12-02
    • Data Source
      KAKENHI-PROJECT-22390351
  • [Presentation] Noncanonical Wnt signaling and osteoclastogenesis2010

    • Author(s)
      Naoyuki Takahashi
    • Organizer
      22nd Meeting of Korean Society of Bone Metabolism
    • Place of Presentation
      Sheraton Grande Walkerhill, 韓国
    • Year and Date
      2010-11-13
    • Data Source
      KAKENHI-PROJECT-22390351
  • [Presentation] 骨吸収を調節するRANKL-RANK 系2010

    • Author(s)
      高橋直之
    • Organizer
      第28回日本骨代謝会学術集会, ランチョンセミナー
    • Place of Presentation
      京王プラザホテル、東京
    • Year and Date
      2010-07-21
    • Data Source
      KAKENHI-PROJECT-22659339
  • [Presentation] 漢方牛蒡子由来のアルクチゲニンは破骨細胞の機能と分化を抑制する2010

    • Author(s)
      山下照仁、上原俊介、小林泰浩、宇田川信之、高橋直之
    • Organizer
      第28回日本骨代謝学会学術大会
    • Place of Presentation
      東京
    • Year and Date
      2010-07-21
    • Data Source
      KAKENHI-PROJECT-21390551
  • [Presentation] Noncanonical Wnt signaling and osteoclastogenesis. Invited lecture2010

    • Author(s)
      Naoyuki Takahashi
    • Organizer
      Satellite Symposium) 22nd Meeting of Korean Society of Bone Metabolism
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2010-11-13
    • Data Source
      KAKENHI-PROJECT-22390351
  • [Presentation] Noncanonical Wnt signaling and osteoclastogenesis2010

    • Author(s)
      Naoyuki Takahashi
    • Organizer
      22nd Meeting of Korean Society of Bone Metabolism
    • Place of Presentation
      Sheraton Grande Walkerhill, 韓国
    • Year and Date
      2010-11-13
    • Data Source
      KAKENHI-PROJECT-22659339
  • [Presentation] 骨吸収を調節するRANKL-RANK 系. ランチョンセミナー2010

    • Author(s)
      高橋直之
    • Organizer
      第28回日本骨代謝会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2010-07-21
    • Data Source
      KAKENHI-PROJECT-22390351
  • [Presentation] Wnt5aはRANKの発現を亢進し、破骨細胞分化を促進する2010

    • Author(s)
      小林泰浩, 前田和洋、上原俊介、高田伊知郎、加藤茂明、丸毛啓史、宇田川信之、高橋直之
    • Organizer
      第28回日本骨代謝学会学術大会
    • Place of Presentation
      東京
    • Year and Date
      2010-07-21
    • Data Source
      KAKENHI-PROJECT-21390551
  • [Presentation] 破骨細胞前駆細胞の起源と動態.2010

    • Author(s)
      高橋直之
    • Organizer
      第31回に本炎症・再生学会ミニシンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2010-08-06
    • Data Source
      KAKENHI-PROJECT-22390351
  • [Presentation] Wntシグナルによる破骨細胞分化調節機構の解析2010

    • Author(s)
      小林泰浩、溝口利英、上原俊介、高橋直之、宇田川信之
    • Organizer
      第71回松本歯科大学学会例会
    • Place of Presentation
      塩尻
    • Year and Date
      2010-11-13
    • Data Source
      KAKENHI-PROJECT-21390551
  • [Presentation] The RANK ligand-OPG system and a new role of osteoblasts in osteoclastogenesis.2007

    • Author(s)
      Takahashi N
    • Organizer
      ASBMR Meeting of Targeting Bone Remodeling for the Treatment of Osteoporosis
    • Place of Presentation
      Washington DC, USA
    • Year and Date
      2007-12-06
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390495
  • [Presentation] A new role of osteoblasts in osteoclastogenesis.2007

    • Author(s)
      Takahashi N
    • Organizer
      The 22nd annual Research Meeting of the Japanese Orthopaedic Association
    • Place of Presentation
      Hamamatsu
    • Year and Date
      2007-10-25
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390495
  • [Presentation] In vivoにおいて細胞周期の停止した破骨細胞前駆細胞(pOCP)は5-FU非感受性である2007

    • Author(s)
      溝口利英、武藤昭紀、細矢明宏、中道裕子、山下照仁、小林泰浩、宇田川信之、伊藤充雄、高橋直之
    • Organizer
      日本骨代謝学会
    • Place of Presentation
      大阪市大阪国際会議場
    • Year and Date
      2007-07-21
    • Data Source
      KAKENHI-PROJECT-19592163
  • [Presentation] 骨吸収を調節する骨芽細胞の新しい役割2007

    • Author(s)
      高橋 直之
    • Organizer
      第22回日本整形外科学会基礎学術集会
    • Place of Presentation
      浜松市
    • Year and Date
      2007-10-25
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18390495
  • [Presentation] The RANK ligand-OPG system and a new role of osteoblasts in osteoclastogenesis2007

    • Author(s)
      Takahashi N
    • Organizer
      ASBMR Meeting of Targeting Bone Remodeling for the Treatment of Osteoporosis.
    • Place of Presentation
      Washington DC,USA
    • Year and Date
      2007-12-06
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18390495
  • [Presentation] The RANK ligand-OPG system and a new role of osteoblasts in osteoclastogenesis2007

    • Author(s)
      Naoyuki Takahashi
    • Organizer
      米国骨代謝学会(ASBMR)Meeting of Targeting Bone Remodeling for the Treatment of Osteoporosis
    • Place of Presentation
      Washington DC
    • Year and Date
      2007-12-06
    • Data Source
      KAKENHI-PROJECT-18390495
  • [Presentation] 破骨細胞のMAPキナーゼp38経路を制御する因子Alixの同定2007

    • Author(s)
      山下照仁、溝口利英、小林泰浩、二宮 禎、宇田川信之、高橋直之
    • Organizer
      日本骨代謝学会
    • Place of Presentation
      大阪市大阪国際会議場
    • Year and Date
      2007-07-21
    • Data Source
      KAKENHI-PROJECT-19592163
  • [Presentation] 骨芽細胞による骨吸収調節機構-新しい考え方-2007

    • Author(s)
      高橋直之
    • Organizer
      第2回信州骨粗鬆症セミナー
    • Place of Presentation
      松本市
    • Year and Date
      2007-09-22
    • Data Source
      KAKENHI-PROJECT-18390495
  • [Presentation] 骨吸収を調節する骨芽細胞の新しい役割2007

    • Author(s)
      高橋直之
    • Organizer
      第22回日本整形外科学会基礎学術集会教育講演
    • Place of Presentation
      浜松市
    • Year and Date
      2007-10-25
    • Data Source
      KAKENHI-PROJECT-18390495
  • [Presentation] チタンインプラント埋入における生体側のイベント

    • Author(s)
      高橋直之
    • Organizer
      Dentistry Quo Vadis?
    • Place of Presentation
      星陵会館 (東京)
    • Invited
    • Data Source
      KAKENHI-PROJECT-24659833
  • [Presentation] Mechanism of inhibitory action of eldecalcitol, an active vitamin D analog, on bone resorption in vivo.

    • Author(s)
      Takahashi naoyuki
    • Organizer
      5th Workshop on Vitamin D
    • Place of Presentation
      Huston、米国
    • Invited
    • Data Source
      KAKENHI-PROJECT-22390351
  • [Presentation] 骨芽細胞と破骨細胞、そして力の関係

    • Author(s)
      高橋直之
    • Organizer
      Dentistry、Quo Vadis?
    • Place of Presentation
      星陵会館(東京都、千代田区)
    • Invited
    • Data Source
      KAKENHI-PROJECT-24659833
  • [Presentation] 破骨細胞の分化と機能の調節機構

    • Author(s)
      高橋直之
    • Organizer
      第86回日本整形外科学会学術総会
    • Place of Presentation
      広島グリーンアリーナ[広島県、広島市)
    • Invited
    • Data Source
      KAKENHI-PROJECT-24659833
  • [Presentation] Mechanism of anti-bone resorptive action of eldecalcitol.

    • Author(s)
      Naoyuki Takahashi
    • Organizer
      Advisory meeting of active vitamin D
    • Place of Presentation
      神戸ポートピアホテル(兵庫県、神戸市)
    • Invited
    • Data Source
      KAKENHI-PROJECT-24659833
  • [Presentation] TRAP marks as vestiges of polarized osteoclasts. 6th International symposium on the biology of tartrate resistant acid phosphatase.

    • Author(s)
      Naoyuki Takahashi
    • Organizer
      6th International symposium on the biology of tartrate resistant acid phosphatase.
    • Place of Presentation
      神戸ポートピアホテル(兵庫県、神戸市)
    • Invited
    • Data Source
      KAKENHI-PROJECT-24659833
  • [Presentation] Arctigenin Inhibits Transcriptional Activity of NFATc1 by Its Nuclear Translocation- Independent Mechanism

    • Author(s)
      Yamashita T,Uehara S,Udagawa N,Kobayashi Y,Takahashi N
    • Organizer
      国際骨代謝学会および日本骨代謝学会
    • Place of Presentation
      ポートピアホテル(神戸市)
    • Data Source
      KAKENHI-PROJECT-24592821
  • [Presentation] 破骨細胞の分化に必須な因子NFATc1の転写活性を抑制するアルクチゲニンの作用メカニズム

    • Author(s)
      山下照仁,李峰,上原俊介,小林泰浩,宇田川信之,門田重利,高橋直之
    • Organizer
      松本歯科大学学会
    • Place of Presentation
      松本歯科大学(塩尻市)
    • Data Source
      KAKENHI-PROJECT-24592821
  • [Presentation] TRAP marks as vestiges of polarized osteoclasts.

    • Author(s)
      Naoyuki Takahashi
    • Organizer
      6th International Symposium on the Biology of Tartrate Resistant Acid Phosphatase.
    • Place of Presentation
      Kobe Potopia hotel
    • Invited
    • Data Source
      KAKENHI-PROJECT-25253097
  • [Presentation] 破骨細胞はどのように骨を認識し極性化するか

    • Author(s)
      高橋直之
    • Organizer
      日本歯科理工学会・中部支部夏季セミナー
    • Place of Presentation
      赤倉ホテル(新潟県妙高市)
    • Invited
    • Data Source
      KAKENHI-PROJECT-24659833
  • 1.  UDAGAWA Nobuyuki (70245801)
    # of Collaborated Projects: 35 results
    # of Collaborated Products: 0 results
  • 2.  SUDA Tatsuo (90014034)
    # of Collaborated Projects: 24 results
    # of Collaborated Products: 0 results
  • 3.  KOBAYASHI Yasuhiro (20264252)
    # of Collaborated Projects: 14 results
    # of Collaborated Products: 53 results
  • 4.  MIZOGUCHI Toshihide (90329475)
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    # of Collaborated Products: 26 results
  • 5.  MIYAURA Chisato (20138382)
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    # of Collaborated Products: 52 results
  • 6.  KATAGIRI Takenobu (80245802)
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    # of Collaborated Projects: 3 results
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    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 63.  KADOTA Shigetoshi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 64.  KIKUCHI Takanobu
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 65.  MUTO Akinori
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 66.  KOBAYASHI Yukiho
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 67.  NISHITA MICHIRU
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 68.  TAKADA Ichiro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 69.  MAEDA Kazuhiro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results
  • 70.  YOKOO Tomotaka
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 71.  ARAI Atsushi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 5 results
  • 72.  YAMAUCHI Hirose
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 73.  THIRUKONDA Gnanasagar
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 74.  USUI Yuki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 75.  KIM Yong jung
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 76.  NAKAMURA Maki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 77.  HARA Kazuo
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 78.  OKAMOTO Masanori
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 79.  KOBAYASHI Shinsuke
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 80.  山本 雅
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 81.  森山 啓司
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 82.  早田 匡芳
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 83.  野田 政樹
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 84.  村上 康平
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 4 results
  • 85.  浅田 梨絵
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 86.  金本 聡自
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 87.  今泉 和則
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 88.  金子 雅幸
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 89.  吉成 伸夫
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 90.  飯村 忠浩
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 91.  向井 秀幸
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 92.  岡橋 暢夫
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 93.  安孫子 宜光
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 94.  羽二生 久夫
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 95.  斎藤 直人
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 96.  KIM YOONG AHM
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 97.  遠藤 守信
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 98.  森石 武史
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 99.  小守 壽文
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 100.  加藤 博之
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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