Ueda Kohei 上田浩平

… Alternative Names

上田浩平ウエダコウヘイ

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Researcher Number	80735697
Other IDs	https://orcid.org/0000-0002-9411-1611
Affiliation (Current)	2025: 国際医療福祉大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2023: 国際医療福祉大学, 医学部, 講師 2020: 東京大学, 先端科学技術研究センター, 特任研究員 2015 – 2017: 東京大学, 先端科学技術研究センター, 特任研究員
Review Section/Research Field	Principal Investigator Basic Section 48020:Physiology-related / Kidney internal medicine Except Principal Investigator Kidney internal medicine
Keywords	Principal Investigator 夜間高血圧 / 血圧日内変動 Except Principal Investigator 高血圧学 / コルチゾール / 内科 / ミネラルコルチコイド / DOHaD / ミネラルコルチコイド受容体 / 加齢 / 糖尿病性腎臓病 … More / 食塩感受性高血圧 / アルドステロン / 腎臓病 / 高血圧 / エピジェネティクス / 環境因子 / 糖質コルチコイド / 鉱質コルチコイド / ミネラロコルチコイド受容体 Less

The mechanism of non-dipper blood pressure induced by intermittent hypoxia during sleepPrincipal Investigator
- Principal Investigator
  
  上田浩平
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48020:Physiology-related
- Research Institution
  International University of Health and Welfare
The mechanism of nocturnal hypertensionPrincipal Investigator
- Principal Investigator
  
  Ueda Kohei
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Kidney internal medicine
- Research Institution
  The University of Tokyo
Development of a novel strategy for life style disease through exploration of the roles of mineral- and gluco-corticoids in hypertension and organ dysfunction
- Principal Investigator
  
  FUJITA Toshiro
- Project Period (FY)
  2015 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Kidney internal medicine
- Research Institution
  The University of Tokyo

All 2020 2019 2018 2017 2016 2015 Other

All Journal Article Presentation Other

[Journal Article] Salt causes aging-associated hypertension via vascular Wnt5a under Klotho deficiency2020
- Author(s)
  Kawarazaki Wakako、Mizuno Risuke、Nishimoto Mitsuhiro、Ayuzawa Nobuhiro、Hirohama Daigoro、Ueda Kohei、Kawakami-Mori Fumiko、Oba Shigeyoshi、Marumo Takeshi、Fujita Toshiro
- Journal Title
  
  Journal of Clinical Investigation
  
  Volume: 130 Pages: 4152-4166
- DOI
  10.1172/jci134431
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08672, KAKENHI-PROJECT-19K17732, KAKENHI-PROJECT-15H05788, KAKENHI-PROJECT-18K08028, KAKENHI-PROJECT-19K22984
[Journal Article] Mineralocorticoid receptor blockade suppresses dietary salt-induced ACEI/ARB-resistant albuminuria in non-diabetic hypertension: a sub-analysis of evaluate study2019
- Author(s)
  Nishimoto Mitsuhiro、Ohtsu Hiroshi、Marumo Takeshi、Kawarazaki Wakako、Ayuzawa Nobuhiro、Ueda Kohei、Hirohama Daigoro、Kawakami-Mori Fumiko、Shibata Shigeru、Nagase Miki、Isshiki Masashi、Oba Shigeyoshi、Shimosawa Tatsuo、Fujita Toshiro
- Journal Title
  
  Hypertension Research
  
  Volume: 42 Issue: 4 Pages: 514-521
- DOI
  10.1038/s41440-018-0201-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06841, KAKENHI-PROJECT-18K12134, KAKENHI-PROJECT-15H05788, KAKENHI-PROJECT-17K16075, KAKENHI-PROJECT-17K09736, KAKENHI-PROJECT-18K19533
[Journal Article] Podocyte Injury Augments Intrarenal Angiotensin II Generation and Sodium Retention in a Megalin-Dependent Manner2019
- Author(s)
  Koizumi Masahiro、Ueda Kohei、Niimura Fumio、Nishiyama Akira、Yanagita Motoko、Saito Akihiko、Pastan Ira、Fujita Toshiro、Fukagawa Masafumi、Matsusaka Taiji
- Journal Title
  
  Hypertension
  
  Volume: 74 Issue: 3 Pages: 509-517
- DOI
  10.1161/hypertensionaha.118.12352
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08254, KAKENHI-PROJECT-19K22628, KAKENHI-PROJECT-18H02827, KAKENHI-PROJECT-17K16100, KAKENHI-PROJECT-15H05788
[Journal Article] Aberrant DNA methylation of pregnane X receptor underlies metabolic gene alterations in the diabetic kidney2018
- Author(s)
  Uchida K, Tanaka Y, Ichikawa H, Watanabe M, Mitani S, Morita K, Fujii H, Ishikawa M, Yoshino G, Okinaga H, Nagae G, Aburatani H, Ikeda Y, Susa T, Tamamori-Adachi M, Fukusato T, Uozaki H, Okazaki T, Iizuka M
- Journal Title
  
  American Journal of Physiology-Renal Physiology
  
  Volume: 314 Issue: 4 Pages: F551-F560
- DOI
  10.1152/ajprenal.00390.2017
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08987, KAKENHI-PROJECT-16K15466, KAKENHI-PROJECT-15H05788, KAKENHI-PROJECT-16K15494, KAKENHI-PROJECT-15K19443, KAKENHI-PROJECT-17K16074
[Journal Article] Renal dysfunction induced by kidney-specific gene deletion of Hsd11b2 as a primary cause of salt-dependent hypertension2017
- Author(s)
  Kohei Ueda, Mitsuhiro Nishimoto, Daigoro Hirohama, Nobuhiro Ayuzawa, Wakako Kawarazaki, Atsushi Watanabe, Tatsuo Shimosawa, Johannes Loffing, Ming-Zhi Zhang, Takeshi Marumo, Toshiro Fujita
- Journal Title
  
  Hypertension
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19442
[Journal Article] Rac1-Mediated Activation of Mineralocorticoid Receptor in Pressure Overload-Induced Cardiac Injury2016
- Author(s)
  Nobuhiro Ayuzawa, Miki Nagase, Kohei Ueda, Mitsuhiro Nishimoto, Wakako Kawarazaki, Takeshi Marumo, Atsu Aiba, Takayuki Sakurai, Takayuki Shindo, Toshiro Fujita
- Journal Title
  
  Hypertension
  
  Volume: 67 Issue: 1 Pages: 99-106
- DOI
  10.1161/hypertensionaha.115.06054
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26860546, KAKENHI-PROJECT-15H05788, KAKENHI-PROJECT-25461230, KAKENHI-PROJECT-26670153, KAKENHI-PROJECT-26670426, KAKENHI-PROJECT-26670427, KAKENHI-PROJECT-26293085
[Presentation] Mineralocorticoid receptor in renal intercalated cells mediates RAAS-driven pendrin regulation to maintain fluid homeostasis2018
- Author(s)
  Nobuhiro Ayuzawa, Mitsuhiro Nishimoto, Daigoro Hirohama, Kohei Ueda, Wakako Kawarazaki, Tastuo Shimosawa, Takeshi Marumo, Toshiro Fujita.
- Organizer
  第61回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] Aldosterone is essential for angiotensin II-induced upregulation of pendrin2018
- Author(s)
  Daigoro Hirohama, Nobuhiro Ayuzawa, Kohei Ueda, Mitsuhiro Nishimoto, Wakako Kawarazaki, Tatsuo Shimosawa, Takeshi Marumo, Shigeru Shibata, Toshiro Fujita
- Organizer
  International Aldosterone Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] 腎臓特異的DNAメチル化を尿中マーカーとした糖尿病性腎症の尿細管障害診断法2018
- Author(s)
  丸茂丈史、下澤達雄、河原崎和歌子、西本光宏、鮎澤信宏、広浜大五郎、上田浩平、佐藤敦久、渥美義仁、星野純一、乳原善文、藤田敏郎
- Organizer
  第61回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] Pendrinの血圧・水電解質代謝調節作用に関する検討2018
- Author(s)
  広浜大五郎、鮎澤信宏、上田浩平、西本光宏、河原崎和歌子、下澤達雄、丸茂丈史、柴田茂、藤田敏郎
- Organizer
  第22回日本心血管内分泌代謝学会
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] Mineralocorticoid receptor in renal intercalated cells mediates pendrin regulation by renin-angiotensin-aldosterone system to maintain fluid homeostasis2018
- Author(s)
  Nobuhiro Ayuzawa, Mitsuhiro Nishimoto, Daigoro Hirohama, Kohei Ueda, Wakako Kawarazaki, Tastuo Shimosawa, Takeshi Marumo, Toshiro Fujita
- Organizer
  Gordon Research Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] 加齢に伴う食塩感受性高血圧発症機序の検討2018
- Author(s)
  河原崎和歌子、水野理介、西本光宏、鮎澤信宏、広浜大五郎、上田浩平、丸茂丈史、藤田敏郎
- Organizer
  第61回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] 腎間在細胞ミネラロコルチコイド受容体欠損マウスを用いたPendrin制御機構の解析2017
- Author(s)
  鮎澤信宏、上田浩平、広浜大五郎、西本光宏、河原崎和歌子、渡邉篤史、丸茂丈史、藤田敏郎
- Organizer
  第60回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] 食塩感受性高血圧の内分泌学的および腎生理学的検討2017
- Author(s)
  西本光宏、上田浩平、河原崎和歌子、水野理介、森典子、渡邉篤史、広浜大五郎、鮎澤信宏、大庭成喜、丸茂丈史、藤田敏郎
- Organizer
  第90回日本内分泌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] 腎臓特異的な11beta HSD2活性低下による高血圧発症機序の解析2017
- Author(s)
  上田浩平、西本光宏、広浜大五郎、鮎澤信宏、河原崎和歌子、渡邉篤史、下澤達雄、丸茂丈史、藤田敏郎
- Organizer
  第40回日本高血圧学会総会
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] 腎pendrinの発現機構と血圧調節における役割の解明2017
- Author(s)
  広浜大五郎、鮎澤信宏、上田浩平、西本光宏、河原崎和歌子、渡邉篤史、下澤達雄、丸茂丈史、柴田茂、藤田敏郎
- Organizer
  第21回心血管内分泌代謝学会学術総会
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] PendrinとNCC発現調節におけるアンジオテンシンIIとアルドステロンの異なる役割2017
- Author(s)
  広浜大五郎、柴田茂、上田浩平、鮎澤信宏、西本光宏、河原崎和歌子、渡邉篤史、下澤達雄、丸茂丈史、藤田敏郎
- Organizer
  第60回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] 糖尿病腎メサンギウム細胞のDNAメチル化異常によるTGFｂ発現増加をRA系阻害薬は抑制する2017
- Author(s)
  大庭成喜、広浜大五郎、鮎澤信宏、西本光宏、河原崎和歌子、上田浩平、下澤達雄、丸茂丈史、藤田敏郎
- Organizer
  第40回日本高血圧学会総会
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] 特異的DNAメチル化signatureを用いた糖尿病性腎症の尿細管障害診断2017
- Author(s)
  丸茂丈史、下澤達雄、河原崎和歌子、西本光宏、鮎澤信宏、広浜大五郎、上田浩平、渡邉篤史、星野純一、乳原善文、藤田敏郎
- Organizer
  第60回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] 抗加齢因子Klothoの発現低下は腎mTORC1の活性化を介して食塩感受性高血圧を惹起する2017
- Author(s)
  河原崎和歌子、西本光宏、鮎澤信宏、広浜大五郎、上田浩平、渡邉篤史、丸茂丈史、藤田敏郎
- Organizer
  第60回日本腎臓学会総会
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] Aldosterone is essential for angiotensin II-induced upregulation of pendrin2017
- Author(s)
  Daigoro Hirohama, Nobuhiro Ayuzawa, Kohei Ueda, Mitsuhiro Nishimoto,Wakako Kawarazaki, Atsushi Watanabe, Tatsuo Shimosawa, Takeshi Marumo, Shigeru Shibata, Toshiro Fujita
- Organizer
  American Society of Nephrology Kidney Week 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] 糖尿病性腎症でエピゲノム異常をきたす核内受容体PXRは腎糖新生を調整する2017
- Author(s)
  渡邉篤史丸茂丈史河原崎和歌子西本光宏鮎澤信宏広浜大五郎上田浩平熊谷裕生藤田敏郎
- Organizer
  第60回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] 加齢と食塩感受性高血圧～抗加齢因子Klothoの発現低下はRhoA活性化による血管収縮を惹起する～2017
- Author(s)
  河原崎和歌子、水野理介、西本光宏、鮎澤信宏、広浜大五郎、上田浩平、渡邉篤史、丸茂丈史、藤田敏郎
- Organizer
  第40回日本高血圧学会総会
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] Systemic effect of renal 11beta-HSD2 deficiency on blood pressure regulation2017
- Author(s)
  Kohei Ueda, Mitsuhiro Nishimoto, Daigoro Hirohama, Nobuhiro Ayuzawa, Wakako Kawarazaki, Atsushi Watanabe, Tatsuo Shimosawa, Johannes Loffing, Ming-Zhi Zhang, Takeshi Marumo, Toshiro Fujita
- Organizer
  AHA Council on Hypertension American Society of Hypertension Joint Scientific Sessions
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] The mechanism of blood pressure elevation in distal nephron-specific Hsd11b2 knockout mice2016
- Author(s)
  Kohei Ueda, Mitsuhiro Nishimoto, Wakako Kawarazaki, Nobuhiro Ayuzawa, Daigoro Hirohama, Atsushi Watanabe, Takeshi Marumo, Toshiro Fujita
- Organizer
  The 41st International Aldosterone Conference Aldosterone and Mineralocorticoids
- Place of Presentation
  Boston, USA
- Year and Date
  2016-03-30
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] PendrinとNCC発現調節におけるアンジオテンシンIIとアルドステロンの異なる役割2016
- Author(s)
  広浜大五郎, 柴田茂, 上田浩平, 鮎澤信宏, 西本光宏, 河原崎和歌子, 渡邉篤史, 丸茂丈史, 藤田敏郎
- Organizer
  第59回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] The mechanism of blood pressure elevation in distal nephron-specific Hsd11b2 knockout mice2016
- Author(s)
  Kohei Ueda, Mitsuhiro Nishimoto, Wakako Kawarazaki, Nobuhiro Ayuzawa, Daigoro Hirohama, Atsushi Watanabe, Takeshi Marumo, Toshiro Fujita
- Organizer
  41st International Aldosterone Conference
- Place of Presentation
  Boston, USA
- Year and Date
  2016-03-30
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19442
[Presentation] The mechanism of blood pressure elevation in kidney-specific Hsd11b2 knockout mice2016
- Author(s)
  Kohei Ueda
- Organizer
  ISH 2016 satellite symposium Renin-angiotensin-aldosterone system
- Place of Presentation
  Tokyo, Japan
- Year and Date
  2016-09-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19442
[Presentation] 抗加齢因子Klotho発現低下に伴う食塩感受性高血圧発症機序の解明2016
- Author(s)
  河原崎和歌子, 丸茂丈史, 西本光宏, 鮎澤信宏, 広浜大五郎, 上田浩平, 渡邉篤史, 藤田敏郎
- Organizer
  第59回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] 間在細胞EGFP標識マウスを用いた間在細胞分取・解析法の確立2016
- Author(s)
  鮎澤信宏, 上田浩平, 広浜大五郎, 西本光宏, 河原崎和歌子, 渡邉篤史, 丸茂丈史, 藤田敏郎
- Organizer
  第59回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] 遠位ネフロン特異的Rac1欠損マウスを用いたRac1-ミネラロコルチコイド受容体（MR）経路の解析2015
- Author(s)
  鮎澤信宏、上田浩平、広浜大五郎、西本光宏、河原崎和歌子、渡邉篤史、丸茂丈史、藤田敏郎
- Organizer
  第58回日本腎臓学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2015-06-05
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] Eplerenoneは塩分過剰摂取によるRA系阻害抵抗性腎障害を抑制する−EVALUATE試験サブ解析−2015
- Author(s)
  西本光宏、大津洋、丸茂丈史、河原崎和歌子、鮎澤信宏、上田浩平、広浜大五郎、渡邉篤史、藤田敏郎
- Organizer
  第58回日本腎臓学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2015-06-05
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] Epigenetic abnormalities underlie increased expression of nuclear receptor PXR in diabetic kidney disease2015
- Author(s)
  Atsushi Watanabe, Takeshi Marumo, Wakako Kawarazaki, Mitsuhiro Nishimoto, Nobuhiro Ayuzawa, Daigoro Hirohama, Kohei Ueda, Hiroo Kumagai, Toshiro Fujita
- Organizer
  Kidney Week 2015 ASN Annual Meeting
- Place of Presentation
  San Diego, USA
- Year and Date
  2015-11-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05788
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1. 下澤達雄 (90231365)

# of Collaborated Projects: 2 results

# of Collaborated Products: 12 results
2. FUJITA Toshiro (10114125)

# of Collaborated Projects: 1 results

# of Collaborated Products: 25 results
3. 丸茂丈史 (70265817)

# of Collaborated Projects: 1 results

# of Collaborated Products: 25 results
4. 河原崎和歌子 (50424594)

# of Collaborated Projects: 1 results

# of Collaborated Products: 25 results
5. 西本光宏 (90646572)

# of Collaborated Projects: 1 results

# of Collaborated Products: 26 results
6. 鮎澤信宏 (50459517)

# of Collaborated Projects: 1 results

# of Collaborated Products: 26 results
7. 広浜大五郎 (20749353)

# of Collaborated Projects: 1 results

# of Collaborated Products: 25 results
8. 柴田茂 (60508068)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
9. 大庭成喜 (80361492)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
10. 森典子 (80431857)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. 永江玄太

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 長瀬美樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 深川雅史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ueda Kohei 上田 浩平

上田 浩平 ウエダ コウヘイ

Research Projects

Research Products

Co-Researchers

The mechanism of non-dipper blood pressure induced by intermittent hypoxia during sleepPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The mechanism of nocturnal hypertensionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of a novel strategy for life style disease through exploration of the roles of mineral- and gluco-corticoids in hypertension and organ dysfunction

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Salt causes aging-associated hypertension via vascular Wnt5a under Klotho deficiency2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Mineralocorticoid receptor blockade suppresses dietary salt-induced ACEI/ARB-resistant albuminuria in non-diabetic hypertension: a sub-analysis of evaluate study2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Podocyte Injury Augments Intrarenal Angiotensin II Generation and Sodium Retention in a Megalin-Dependent Manner2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Aberrant DNA methylation of pregnane X receptor underlies metabolic gene alterations in the diabetic kidney2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Renal dysfunction induced by kidney-specific gene deletion of Hsd11b2 as a primary cause of salt-dependent hypertension2017

Author(s)

Journal Title

Data Source

[Journal Article] Rac1-Mediated Activation of Mineralocorticoid Receptor in Pressure Overload-Induced Cardiac Injury2016

Author(s)

Journal Title

DOI

Data Source

[Presentation] Mineralocorticoid receptor in renal intercalated cells mediates RAAS-driven pendrin regulation to maintain fluid homeostasis2018

Author(s)

Organizer

Data Source

[Presentation] Aldosterone is essential for angiotensin II-induced upregulation of pendrin2018

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[Presentation] 腎臓特異的DNAメチル化を尿中マーカーとした糖尿病性腎症の尿細管障害診断法2018

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[Presentation] Pendrinの血圧・水電解質代謝調節作用に関する検討2018

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[Presentation] Mineralocorticoid receptor in renal intercalated cells mediates pendrin regulation by renin-angiotensin-aldosterone system to maintain fluid homeostasis2018

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[Presentation] 加齢に伴う食塩感受性高血圧発症機序の検討2018

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[Presentation] 腎間在細胞ミネラロコルチコイド受容体欠損マウスを用いたPendrin制御機構の解析2017

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Ueda Kohei 上田浩平

上田浩平ウエダコウヘイ

[Presentation] 腎pendrinの発現機構と血圧調節における役割の解明2017