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Ushijima Toshikazu  牛島 俊和

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… Alternative Names

USHIJIMA Toshikazu  牛島 俊和

牛島 俊和  ウシジマ トシカズ

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Researcher Number 90232818
Other IDs
Affiliation (Current) 2025: 星薬科大学, 薬学部, 学長
Affiliation (based on the past Project Information) *help 2022 – 2024: 星薬科大学, 薬学部, 学長
2022 – 2023: 国立研究開発法人国立がん研究センター, その他部局等, 次長
2015 – 2021: 国立研究開発法人国立がん研究センター, 研究所, 分野長
2015: 国立がん研究センター, エピゲノム解析分野, 分野長
2014: 国立がんセンター(研究所及び東病院臨床開発センター), 発がん研究部, 部長 … More
2014: 独立行政法人国立がん研究センター, 研究所
2013 – 2014: 独立行政法人国立がん研究センター, その他部局等, その他
2012: 独立行政法人国立がん研究センター, その他部局等, 分野長
2009: National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East, 発がん研究部, 部長
2005 – 2009: 国立がんセンター(研究所及び東病院臨床開発センター), 発がん研究部, 部長
2004: National Cancer Center Research Institute, Chief, 部長
2004: 国立がんセンター(研究所), 発がん研究部, 部長
2003: 国立がんセンター研究所, 部長
2003: 国立がんセンター研究所, 発ガン研究部, 部長(研究職)
2002: 国立がんセンター, 研究所, 部長
2002: 国立がんセンター, 研究所, 部長(研究職)
2001: 国立がんセンター, 研究所・発ガン研究部, 部長
2001: 国立がんセンター研究所, 発癌研究部, 部長
2000: National Cancer Center Res.Inst.Chief, 部長
1999 – 2000: 国立がんセンター研究所, 発がん研究部, 部長
1997 – 1998: 国立がんセンター, 研究員
1997: 国立がんセンター, 研究所・発がん研究部, 室長
1996: 国立がんセンター研究所, 発がん研究部, 室長
1994: 国立がんセンター, 発がん研究部, 室長
1993: 国立がんセ, 研, 研究員
1993: 国立がんセンター研究所, 発がん研究部, 研究員 Less
Review Section/Research Field
Principal Investigator
Basic Section 50010:Tumor biology-related / Biological Sciences / Basic Section 50020:Tumor diagnostics and therapeutics-related / Tumor biology
Except Principal Investigator
Basic Section 58020:Hygiene and public health-related: including laboratory approach / Basic Section 53010:Gastroenterology-related / Basic Section 52050:Embryonic medicine and pediatrics-related / Neurosurgery / Gastroenterology / Biological Sciences / Biological Sciences / Urology
Keywords
Principal Investigator
エピジェネティクス / MS-RDA / DNAメチル化 / Lysyl oxidase / DNA methylation / メチル化 / CpGアイランド / 胃がん / がん予防 / DNAメチル化異常 … More / 慢性炎症 / ヌクレオソーム振動 / 合成致死 / エピゲノム / lncRNA / 効果予測マーカー / DNA脱メチル化治療 / CpG islands / Rat / Gastric cancers / Genome-wide screening / Epigenetics / gp115 / MNNG / Filamin / Thrombomodulin / LOX / HRASLS / ラット / ゲノム網羅的 / エピジェネティック / Methylation instability / Maintenance / G protein / BRCA1 / Breast cancer / CpG island / セカンドメッセンジャー / 維持機構 / Gタンパク質 / BRCA1遺伝子 / 乳癌 / MS-RDA法 / CpGアイランドメチル化形質 / ユビジェネティクス / ゲノム網羅的解析 / DNAメチルヒ / サイレンシング / ゲノム … More
Except Principal Investigator
PhIP / LOH / 発癌リスク層別化 / Helicobacter pylori / 自己免疫性胃炎 / マイクロアレイ / 遺伝子変異 / エピゲノム / 除菌後フォロー体制 / 胃組織DNAメチル化解析 / 除菌治療後胃粘膜 / 診断精度 / 中学生ピロリ菌検診 / 予防医療実装 / オミックス解析 / エクソーム解析 / ピロリ菌感染胃炎 / エピゲノム解析 / 胃癌 / polycomb / ChIPseq / transcriptome / neuroblastoma / MYCN / nural crest cell / 網羅的解析 / 網羅的ノックアウト / Neural Crest Cell / テロメア異常 / 新規エピゲノム治療開発 / ヒストン修飾 / ゲノムメチル化 / ポリコーム / ゲノム編集 / NCC / iPS / 神経芽腫 / IonTorrent / CGH / 遺伝子診断 / Ion Torrent / グリオーマ / TERT / 分子分類 / 膠芽腫 / 次世代シークエンス / 脳腫瘍 / HCV / H.Pylori / エピゲノム異常 / ゲノム異常 / 組織幹細胞 / 癌幹細胞 / 炎症発癌 / AID / リンパ球 / 造血細胞 / バイオテクノロジー / 発生・分化 / 発現制御 / 核酸 / 遺伝子 / 細胞周期 / 骨髄異形成症候群 / エピジェネティクス / 細胞分化 / 遺伝子トラップ / ノックアウト / トランスジェニック / 遺伝子改変マスウ / 組織診断 / 病理形態学 / データベース / 遺伝学的モニタリング / 微生物学的モニタリング / 凍結保存 / 相同組換え / 遺伝子改変マウス / coenzyume Q / 発癌抑制 / 前立腺発癌 / コレステロール / coenzyme Q / 発ガン抑制 / 発ガン / 前立腺 / p53 / 突然変異スペクトル / β-カテニン / Apc / DNAメチル化 / MSMマウス / 染色体 / PLGS / 肝細胞癌 / L-1RA / TmR2 / 連鎖解析 / differential display / 遺伝子変化 / マウス肝発癌 / MS-RDA / RLGS / mac25 / β-catenin / Igf2 / メチル化 / 肝発癌 / マウス / 発がん感受性 / aberrant crypt focus / microsatellite / 乳がん / 染色体マッピング / PP2AB / Brca-2 / Brca-1 / genomic instability / ヘテロサイクリックアミン / APC / suppressor / oncogene / mouse / carcinogenesis Less
  • Research Projects

    (21 results)
  • Research Products

    (114 results)
  • Co-Researchers

    (69 People)
  •  慢性炎症によるヌクレオソーム振動の分子機構Principal Investigator

    • Principal Investigator
      牛島 俊和
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 50010:Tumor biology-related
    • Research Institution
      Hoshi University
  •  自己免疫性胃炎・ピロリ菌胃炎のオミックス解析による病態解明と予防医療実装への挑戦

    • Principal Investigator
      山道 信毅
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 58020:Hygiene and public health-related: including laboratory approach
    • Research Institution
      The University of Tokyo
  •  Verification of Helicobacter pylori screening for junior high school students: Towards test accuracy and establishment of follow-up system after treatment

    • Principal Investigator
      奥田 真珠美
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Hyogo Medical University
  •  Synthetic lethality with gene silencingPrincipal Investigator

    • Principal Investigator
      Ushijima Toshikazu
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 50010:Tumor biology-related
    • Research Institution
      Hoshi University
      National Cancer Center Japan
  •  Elucidation of carcinogenic mechanisms of autoimmune gastritis and Helicobacter pylori-associated gastritis

    • Principal Investigator
      山道 信毅
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 58020:Hygiene and public health-related: including laboratory approach
    • Research Institution
      The University of Tokyo
  •  Development of epigenome therapy for neuroblastoma by iPS-derived tumor model and genome editing

    • Principal Investigator
      Kamijo Takehiko
    • Project Period (FY)
      2019 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52050:Embryonic medicine and pediatrics-related
    • Research Institution
      Research Institute for Clinical Oncology Saitama Cancer Center
  •  Involvement of lnc162 on sensitivity to DNA demethylating agentsPrincipal Investigator

    • Principal Investigator
      Ushijima Toshikazu
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      National Cancer Center Japan
  •  Clarification of molecular mechanism of aberrant DNA methylation induction by chronic inflammationPrincipal Investigator

    • Principal Investigator
      Ushijima Toshikazu
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Tumor biology
    • Research Institution
      National Cancer Center Japan
  •  Identification of novel prognostic markers for glioblastomas by means of next-generation sequencing-ased targeted resequencing

    • Principal Investigator
      ICHIMURA Koichi
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurosurgery
    • Research Institution
      National Cancer Center Japan
      National Center of Neurology and Psychiatry
  •  Global anallysis of genetic and epigenetic alterations during inflammation-associated gastrointestinal cancer development, and elucidation of its mechanism

    • Principal Investigator
      CHIBA Tsutomu
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Gastroenterology
    • Research Institution
      Kyoto University
  •  Control of cell fate decision in the cells differentiating to multiple pathways in a step-by-step fashion

    • Principal Investigator
      KITAMURA Toshio
    • Project Period (FY)
      2010 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  Integrated cancer research using in vivo models

    • Principal Investigator
      YAMAMURA Kenichi
    • Project Period (FY)
      2005 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kumamoto University
  •  Identification of tumor suppressor genes in gastric cancers by genome-wide analysis of DNA methylation and its functional analysisPrincipal Investigator

    • Principal Investigator
      USHIJIMA Toshikazu
    • Project Period (FY)
      2005 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
  •  酸化ストレスによる前立腺発癌の促進作用とその抑制に関する研究

    • Principal Investigator
      本間 之夫
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      The University of Tokyo
  •  Identification of genes silenced in human gastric cancersPrincipal Investigator

    • Principal Investigator
      USHIJIMA Toshikazu
    • Project Period (FY)
      2000 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      National Cancer Center
  •  Abnormalities in maintenance of methylation and carcinogenesis.Principal Investigator

    • Principal Investigator
      USHIJIMA Toshikazu
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      National Cancer Center Resaerch Institute Carcinogenesis
  •  マウス肝発癌の初期遺伝子変化

    • Principal Investigator
      小川 勝洋
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Asahikawa Medical College
  •  環境発がん物質の遺伝子変異特性

    • Principal Investigator
      長尾 美奈子
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
  •  発がん過程における遺伝子変異

    • Principal Investigator
      長尾 美奈子
    • Project Period (FY)
      1994 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
  •  マウスを中心とする遺伝子レベルの発癌の研究

    • Principal Investigator
      北川 知行
    • Project Period (FY)
      1993 – 1995
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Japanese Foundation For Cancer Research
  •  ヘテロサイクリックアミン誘発実験動物腫瘍における遺伝子変化

    • Principal Investigator
      長尾 美奈子
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2010 2009 2008 2007 2006 2005 2004 2003 2002 2001

All Journal Article Presentation

  • [Journal Article] DNA methylation marker to estimate ovarian cancer cell fraction2022

    • Author(s)
      Ebata Takahiro、Yamashita Satoshi、Takeshima Hideyuki、Yoshida Hiroshi、Kawata Yoshiko、Kino Nao、Yasugi Toshiharu、Terao Yasuhisa、Yonemori Kan、Kato Tomoyasu、Ushijima Toshikazu
    • Journal Title

      Medical Oncology

      Volume: 39 Issue: 5 Pages: 78-78

    • DOI

      10.1007/s12032-022-01679-y

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21H02773, KAKENHI-PROJECT-20K18180
  • [Journal Article] Autoimmune gastritis induces aberrant DNA methylation reflecting its carcinogenic potential.2022

    • Author(s)
      Chihiro Takeuchi, Junichi Sato, Satoshi Yamashita, Akiko Sasaki, Takemi Akahane, Rika Aoki, Mitsue Yamamichi, Yu-Yu Liu, Masayoshi Ito, Takahisa Furuta, Shigemi Nakajima, Yoshiki Sakaguchi, Yu Takahashi, Yosuke Tsuji, Keiko Niimi, Shuta Tomida , Mitsuhiro Fujishiro, Nobutake Yamamichi, Toshikazu Ushijima
    • Journal Title

      J Gastroenterol .

      Volume: 3 Issue: 3 Pages: 144-155

    • DOI

      10.1007/s00535-021-01848-2

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K08073, KAKENHI-PROJECT-21H03178
  • [Journal Article] A quantification method of somatic mutations in normal tissues and their accumulation in pediatric patients with chemotherapy2022

    • Author(s)
      Ueda Sho、Yamashita Satoshi、Nakajima Miho、Kumamoto Tadashi、Ogawa Chitose、Liu Yu-yu、Yamada Harumi、Kubo Emi、Hattori Naoko、Takeshima Hideyuki、Wakabayashi Mika、Iida Naoko、Shiraishi Yuichi、Noguchi Masayuki、Sato Yukio、Ushijima Toshikazu
    • Journal Title

      Proceedings of the National Academy of Sciences

      Volume: 119 Issue: 31

    • DOI

      10.1073/pnas.2123241119

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21H02773
  • [Journal Article] DNA methylation of the immediate upstream region of BRCA1 major transcription start sites is an independent favorable prognostic factor in patients with high-grade serous ovarian cancer2022

    • Author(s)
      Ebata Takahiro、Yamashita Satoshi、Takeshima Hideyuki、Yoshida Hiroshi、Kawata Yoshiko、Kino Nao、Yasugi Toshiharu、Terao Yasuhisa、Yonemori Kan、Kato Tomoyasu、Ushijima Toshikazu
    • Journal Title

      Gynecologic Oncology

      Volume: 167 Issue: 3 Pages: 513-518

    • DOI

      10.1016/j.ygyno.2022.10.008

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21H02773, KAKENHI-PROJECT-20K18180
  • [Journal Article] Combination of a synthetic retinoid and a DNA demethylating agent induced differentiation of neuroblastoma through retinoic acid signal reprogramming2021

    • Author(s)
      Hattori Naoko、Asada Kiyoshi、Miyajima Nozomu、Mori Akiko、Nakanishi Yoko、Kimura Kana、Wakabayashi Mika、Takeshima Hideyuki、Nitani Chika、Hara Junichi、Ushijima Toshikazu
    • Journal Title

      British Journal of Cancer

      Volume: 125 Issue: 12 Pages: 1647-1656

    • DOI

      10.1038/s41416-021-01571-y

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21H02773
  • [Journal Article] Influence of degree of DNA degradation in formalin-fixed and paraffin-embedded tissue samples on accuracy of genome-wide DNA methylation analysis2021

    • Author(s)
      Ueda S, Yamashita S, Watanabe S-i, Wakabayashi M, Motoi N, Noguchi M, Sekine S, Sato Y, Ushijima T.
    • Journal Title

      Epigenomics

      Volume: - Issue: 8 Pages: 565-576

    • DOI

      10.2217/epi-2020-0431

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K07036, KAKENHI-PROJECT-18H02704, KAKENHI-PROJECT-21H02773
  • [Journal Article] Genetic and epigenetic profiling indicates the proximal tubule origin of renal cancers in end‐stage renal disease2020

    • Author(s)
      Ishihara Hiroki、Yamashita Satoshi、Liu Yu‐Yu、Hattori Naoko、El‐Omar Omar、Ikeda Takashi、Fukuda Hironori、Yoshida Kazuhiko、Takagi Toshio、Taneda Sekiko、Kondo Tsunenori、Nagashima Yoji、Tanabe Kazunari、Ushijima Toshikazu
    • Journal Title

      Cancer Science

      Volume: 111 Issue: 11 Pages: 4276-4287

    • DOI

      10.1111/cas.14633

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H02704
  • [Journal Article] エピジェネティック変化2020

    • Author(s)
      牛島俊和
    • Journal Title

      入門腫瘍内科学 改訂第3版

      Volume: - Pages: 36-39

    • Data Source
      KAKENHI-PROJECT-18H02704
  • [Journal Article] エピジェネティクス2020

    • Author(s)
      服部奈緒子、牛島俊和
    • Journal Title

      日本臨床 増刊号 「肉腫」

      Volume: 78 Pages: 95-102

    • NAID

      10018410248

    • Data Source
      KAKENHI-PROJECT-18H02704
  • [Journal Article] SAA1 is upregulated in gastric cancer-associated fibroblasts possibly by its enhancer activation2020

    • Author(s)
      Yasukawa Yoshimi、Hattori Naoko、Iida Naoko、Takeshima Hideyuki、Maeda Masahiro、Kiyono Tohru、Sekine Shigeki、Seto Yasuyuki、Ushijima Toshikazu
    • Journal Title

      Carcinogenesis

      Volume: 42 Issue: 2 Pages: 180-189

    • DOI

      10.1093/carcin/bgaa131

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H02704
  • [Journal Article] Distinct DNA methylation targets by aging and chronic inflammation: a pilot study using gastric mucosa infected with Helicobacter pylori2019

    • Author(s)
      Yamashita Satoshi, Nanjo Sohachi, Rehnberg Emil, Iida Naoko, Takeshima Hideyuki, Ando Takayuki, Maekita Takao, Sugiyama Toshiro, Ushijima Toshikazu
    • Journal Title

      Clinical Epigenetics

      Volume: 11 Issue: 1 Pages: 191-191

    • DOI

      10.1186/s13148-019-0789-8

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H02704
  • [Journal Article] LINC00162 Confers Sensitivity to 5-Aza-2'-deoxycytidine via Modulation of an RNA Splicing Protein, HNRNPH12019

    • Author(s)
      Zong Liang、Hattori Naoko、Yasukawa Yoshimi、Kimura Kana、Mori Akiko、Seto Yasuyuki、Ushijima Toshikazu
    • Journal Title

      Oncogene

      Volume: 印刷中 Issue: 26 Pages: 5281-5293

    • DOI

      10.1038/s41388-019-0792-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18H02704
  • [Journal Article] Epigenetic impact of infection on carcinogenesis: mechanisms and applications2016

    • Author(s)
      Hattori N, Ushijima T
    • Journal Title

      Genome Medicine

      Volume: 8 Issue: 1 Pages: 10-10

    • DOI

      10.1186/s13073-016-0267-2

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H04302, KAKENHI-PROJECT-15K18420
  • [Journal Article] Integrated analysis of cancer-related pathways affected by genetic and epigenetic alterations in gastric cancer2015

    • Author(s)
      Yoda Y, Takeshima H, Niwa T, Kim JG, Ando T, Kushima R, Sugiyama T, Katai H, Noshiro H, Ushijima T
    • Journal Title

      Gastric Cancer

      Volume: 18 Issue: 1 Pages: 65-76

    • DOI

      10.1007/s10120-014-0348-0

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04302
  • [Journal Article] Inflammatory processes triggered by H. pylori infection cause aberrant DNA methylation in gastric epithelial cells.2010

    • Author(s)
      Niwa T, Tsukamoto T, Toyoda T, Mori A, Tanaka H, Maekita T, Ichinose M, Tatematsu M, Ushijima T.
    • Journal Title

      Cancer Res 70

      Pages: 1430-1440

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013090
  • [Journal Article] Methylationsensitive representational difference analysis (MS-RDA).2009

    • Author(s)
      Ushijima T, Yamashita S.
    • Journal Title

      Methods Mol Biol 507

      Pages: 117-130

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013090
  • [Journal Article] RUNX3 expression correlates with chief cell differentiation in human gastric cancers.2009

    • Author(s)
      Ogasawara, N., Tsukamoto, T., Mizoshita, T., Inada, KI., Ban, H., Kondo, S., Takasu, S., Ushijima, T., Ito, K., Ito, Y., Ichinose, M., Ogawa, T., Joh, T., and Tatematsu, M.
    • Journal Title

      Histol Histopathol 24

      Pages: 31-40

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013090
  • [Journal Article] Persistence of a component of DNA methylation in gastric mucosae after Helicobacter pylori eradication.2009

    • Author(s)
      Nakajima T, Enomoto S, Yamashita S, Ando T, Nakanishi Y, Nakazawa K, Oda I, Gotoda T, Ushijima T.
    • Journal Title

      J Gastroenterol 45

      Pages: 37-44

    • NAID

      10027213841

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013090
  • [Journal Article] The presence of a methylation fingerprint of Helicobacter pylori infection in human gastric mucosae.2009

    • Author(s)
      Nakajima T, Yamashita S, Maekita T, Niwa T, Nakazawa K, Ushijima T.
    • Journal Title

      Int J Cancer 124

      Pages: 905-910

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013090
  • [Journal Article] RUNX3 expression correlates with chief cell differentiation in human gastric cancers.2009

    • Author(s)
      Ogasawara N, Tsukamoto T, Mizoshita T, Inada KI, Ban H, Kondo S, Takasu S, Ushijima T, Ito K, ItoY, Ichinose M, Ogawa T, Joh T, Tatematsu M.
    • Journal Title

      Histol Histopathol 24

      Pages: 31-40

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013090
  • [Journal Article] DNA methylation of microRNA genes in gastric mucosae of gastric cancer patients: its possible involvement in the formation of epigenetic field defect.2009

    • Author(s)
      Ando T, Yoshida T, Enomoto S, Asada K, Tatematsu M, Ichinose M, Sugiyama T, Ushijima T.
    • Journal Title

      Int J Cancer 124

      Pages: 2367-2374

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013090
  • [Journal Article] The presence of a methylation fingerprint of Helicobacter pylori infection in human gastric mucosae.2009

    • Author(s)
      Nakajima, T., Yamashita, S., Maekita, T., Niwa, T., Nakazawa, K., and Ushijima, T.
    • Journal Title

      Int J Cancer 124

      Pages: 905-910

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013090
  • [Journal Article] Cyclin D1 overexpression in N-methyl-N'-nitro-Nnitrosoguanidine- induced rat gastric adenocarcinomas.2007

    • Author(s)
      Takasu S, TsukamotoT, Ushijima T, Yamashita S, Ogasawara N, Ban H, Yanai T, Masegi T, Tatematsu M.
    • Journal Title

      Exp Toxicol Pathol 59

      Pages: 171-175

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013090
  • [Journal Article] Larger numbers of silenced genes in cancer cell lines with increased de novo methylation of scattered CpG sites.2007

    • Author(s)
      Moriguchi K, Yamashita S, Tsujino Y, Tatematsu M, Ushijima T.
    • Journal Title

      Cancer Lett 249

      Pages: 178-187

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013090
  • [Journal Article] Epigenetic field for cancerization.2007

    • Author(s)
      Ushijima T.
    • Journal Title

      J Biochem Mol Biol 40

      Pages: 142-150

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013090
  • [Journal Article] Epigenetic field for cancerization.2007

    • Author(s)
      Ushijima, T.
    • Journal Title

      Journal of Biochemistxy and Molecular Biology 40

      Pages: 142-150

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013090
  • [Journal Article] Epigenetic field for cancerization.2007

    • Author(s)
      Ushijima, T.
    • Journal Title

      Journal of Biochemistry and Molecular Biology 40(2)

      Pages: 142-150

    • Data Source
      KAKENHI-PROJECT-17013090
  • [Journal Article] Lack of association between CpG island methylator phenotype in human gastric cancers and methylation in their background non-cancerous gastric mucosae.2007

    • Author(s)
      Enomoto S, Maekita T, Tsukamoto T, Nakajima T, Nakazawa K, Tatematsu M, Ichinose M, Ushijima T.
    • Journal Title

      Cancer Sci 98

      Pages: 1853-1861

    • NAID

      10019996096

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013090
  • [Journal Article] Genome-wide profiling of promoter methylation in human.2006

    • Author(s)
      Hatada I, Fukasawa M, Kimura M, Morita S, Yamada K, Yoshikawa T, Yamanaka S, Endo C, Sakurada A, Sato M, Kondo T, Horii A, Ushijima T, Sasaki H.
    • Journal Title

      Oncogene 25

      Pages: 3059-3064

    • NAID

      120000908395

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013090
  • [Journal Article] A specific CpG site demethylation in the human interleukin 2 gene promoter is an epigenetic memory.2006

    • Author(s)
      Murayama A, Sakura K, Nakama M, Yasuzawa-Tanaka K, Fujita E, Tateishi Y, Wang Y, Ushijima T, Baba T, Shibuya K, Shibuya A, Kawabe Y, Yanagisawa J.
    • Journal Title

      EMBO J 25

      Pages: 1081-1092

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013090
  • [Journal Article] Chemical genomic screening for methylation-silenced genes in gastric cancer cell lines using 5-aza-2'-deoxycytidine treatment and oligonucleotide microarray.2006

    • Author(s)
      Yamashita S, Tsujino Y, Moriguchi K, Tatematsu M, Ushijima T.
    • Journal Title

      Cancer Sci 97

      Pages: 64-71

    • NAID

      10017103807

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013090
  • [Journal Article] Decreased fidelity in replicating CpG methylation patterns in cancer cells.2005

    • Author(s)
      Ushijima, T.他
    • Journal Title

      Cancer Res. 65

      Pages: 11-17

    • Data Source
      KAKENHI-PROJECT-17013090
  • [Journal Article] Decreased fidelity in replicating CpG methylation patterns in cancer cells.2005

    • Author(s)
      Ushijima T, Watanabe N, Shimizu K, Miyamoto K, Sugimura T, Kaneda A.
    • Journal Title

      Cancer Res 65

      Pages: 11-17

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013090
  • [Journal Article] Detection and interpretation of altered methylation in cancer cells.2005

    • Author(s)
      Ushijima, T.
    • Journal Title

      Nat.Reviews Cancer 5

      Pages: 223-231

    • Data Source
      KAKENHI-PROJECT-12213150
  • [Journal Article] Decreased expression of the seven ARP2/3 complex genes in human gastric cancers.2004

    • Author(s)
      Kaneda, A, Kaminishi, M, Sugimura, T, Ushijima, T.
    • Journal Title

      Cancer Lett 212

      Pages: 203-10

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12213150
  • [Journal Article] Focus on gastric cancer.2004

    • Author(s)
      Ushijima, T., Sasako, M.
    • Journal Title

      Cancer Cell 5

      Pages: 121-125

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12213150
  • [Journal Article] Lysyl oxidase is a tumor suppressor gene inactivated by methylation and loss of heterozygosity in human gastric cancers.2004

    • Author(s)
      Kaneda, A, Wakazono, K, Tsukamoto, T, Watanabe, N, Yagi, Y, Tatematsu, M, Kaminishi, M, Sugimura, T, Ushijima, T.
    • Journal Title

      Cancer Res 64

      Pages: 6410-5

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12213150
  • [Journal Article] Frequent hypomethylation in multiple promoter CpG islands is associated with global hypomethylation, but not with frequent promoter hypermethylation.2004

    • Author(s)
      Kaneda, A, Tsukamoto, T, Takamura-Enya, T, Watanabe, N, Kaminishi, M, Sugimura, T, Tatematsu, M, Ushijima, T.
    • Journal Title

      Cancer Sci 95

      Pages: 58-64

    • NAID

      10013721371

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12213150
  • [Journal Article] Focus on gastric cancer.2004

    • Author(s)
      Ushijima, T, Sasako, M.
    • Journal Title

      Cancer Cell 5

      Pages: 121-5

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12213150
  • [Journal Article] Methylation-sensitive representational difference analysis and its application to cancer research.2003

    • Author(s)
      Kaneda, A, Takai, D, Kaminishi, M, Okochi, E, Ushijima, T.
    • Journal Title

      Ann N Y Acad Sci 983

      Pages: 131-41

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12213150
  • [Journal Article] Reduced expression of the insulin-induced protein 1 and p41 Arp2/3 complex genes in human gastric cancers.2002

    • Author(s)
      Kaneda, A, Kaminishi, M, Nakanishi, Y, Sugimura, T, Ushijima, T.
    • Journal Title

      Int J Cancer 100

      Pages: 57-62

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12213150
  • [Journal Article] Identification of silencing of nine genes in human gastric cancers.2002

    • Author(s)
      Kaneda, A, Kaminishi, M, Yanagihara, K, Sugimura, T, Ushijima, T.
    • Journal Title

      Cancer Res 62

      Pages: 6645-50

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12213150
  • [Journal Article] Silencing of HTR1B and reduced expression of EDN1 in human lung cancers, revealed by methylation-sensitive representational difference analysis.2001

    • Author(s)
      Takai, D, Yagi, Y, Wakazono, K, Ohishi, N, Morita, Y, Sugimura, T, Ushijima, T.
    • Journal Title

      Oncogene 20

      Pages: 7505-13

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12213150
  • [Presentation] Screening of methylation synthetic lethality in gastric and colon cancers2023

    • Author(s)
      Furuichi Yumi、Takeshima Hideyuki、Ebata Takahiro、Okano Keiichi、Ushijima Toshikazu
    • Organizer
      Singapore Gastric Cancer Consortium 14th Annual Scientific Meeting in 2023
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H02773
  • [Presentation] メチル化合成致死:胃がんにおけるCHFRメチル化とKRAS阻害2023

    • Author(s)
      竹島秀幸、江畑貴大、古市ゆみ、山下聡、牛島俊和
    • Organizer
      第82回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-21H02773
  • [Presentation] G0S2メチル化胃がん、大腸がんにおける合成致死スクリーニング2023

    • Author(s)
      古市ゆみ、竹島秀幸、江畑貴大、大橋由依、岡野圭一、牛島俊和
    • Organizer
      第46回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-21H02773
  • [Presentation] DNAメチル化を利用したパラログ合成致死2023

    • Author(s)
      江畑貴大、竹島秀幸、古市ゆみ、牛島俊和
    • Organizer
      第46回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-21H02773
  • [Presentation] DNAメチル化を利用したパラログによる合成致死2023

    • Author(s)
      江畑貴大、竹島秀幸、古市ゆみ、牛島俊和
    • Organizer
      第82回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-21H02773
  • [Presentation] Epigenetic field for precision cancer risk diagnosis and exploitation of its carry-over as a synthetic lethal target2023

    • Author(s)
      Ushijima Toshikazu
    • Organizer
      Singapore Gastric Cancer Consortium 14th Annual Scientific Meeting in 2023
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H02773
  • [Presentation] メチル化合成致死:胃がんにおけるCHFRメチル化とKRAS阻害2023

    • Author(s)
      竹島秀幸、江畑貴大、古市ゆみ、大橋由依、奥輝明、山下聡、牛島俊和
    • Organizer
      第46回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-21H02773
  • [Presentation] CHFRメチル化がん細胞を標的とした合成致死2023

    • Author(s)
      大橋由依、竹島秀幸、江畑貴大、古市ゆみ、益子諒真、奥輝明、牛島俊和
    • Organizer
      第46回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-21H02773
  • [Presentation] Epigenetic field for precision cancer risk diagnosis and exploitation of its carry-over as a synthetic lethal target2023

    • Author(s)
      Ushijima Toshikazu
    • Organizer
      Annual Symposium on ‘60 Years Anniversary of SNUCRI: Past, Present and Future’
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H02773
  • [Presentation] 胃がん、大腸がんにおけるメチル化合成致死スクリーニング2023

    • Author(s)
      古市ゆみ、竹島秀幸、江畑貴大、岡野圭一、牛島俊和
    • Organizer
      第82回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-21H02773
  • [Presentation] Methylation synthetic lethality: CHFR methylation and KRAS inhibition in gastric cancers2023

    • Author(s)
      Takeshima Hideyuki、Ebata Takahiro、Furuichi Yumi、Yamashita Satoshi、Ushijima Toshikazu
    • Organizer
      Annual Meeting of AACR
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H02773
  • [Presentation] Methylation synthetic lethality: methylation-silenced genes as a rich source of combination partners for synthetic lethality2022

    • Author(s)
      Ushijima Toshikazu
    • Organizer
      6th Asian Cancer Epigenome Meeting on Tackling Cholangiocarcinoma in ASEAN Countries
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H02773
  • [Presentation] Methylation synthetic lethality: methylation-silenced genes as a rich source of combination partners for synthetic lethality2022

    • Author(s)
      Ushijima Toshikazu、Yamashita Satoshi、Takeshima Hideyuki、Ebata Takahiro、Furuichi Yumi
    • Organizer
      12th AACR-JCA Joint Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H02773
  • [Presentation] DNAメチル化サイレンシングに着目したパラログ合成致死の同定2022

    • Author(s)
      江畑貴大、竹島秀幸、古市ゆみ、牛島俊和
    • Organizer
      第81回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-21H02773
  • [Presentation] 消化器がんにおいて遺伝子Aのメチル化は遺伝子B阻害と合成致死を示す2022

    • Author(s)
      古市ゆみ、竹島秀幸、江畑貴大、岡野圭一、牛島俊和
    • Organizer
      第33回日本消化器癌発生学会総会
    • Data Source
      KAKENHI-PROJECT-21H02773
  • [Presentation] DNA メチル化プロファイルを用いた自己免疫性胃炎診断と発がんリスク予測2022

    • Author(s)
      竹内千尋、山道信毅、牛島俊和
    • Organizer
      JDDW2022
    • Data Source
      KAKENHI-PROJECT-21H03178
  • [Presentation] エピゲノム毒性の評価2021

    • Author(s)
      牛島俊和、服部奈緒子
    • Organizer
      第48回日本毒性学会学術年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21H02773
  • [Presentation] Methylation synthetic lethality: large-scale isolation of candidate combinations2021

    • Author(s)
      山下聡、竹島秀幸、牛島俊和
    • Organizer
      第44回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-21H02773
  • [Presentation] Methylation synthetic lethality: large scale isolation of candidate combinationse2021

    • Author(s)
      山下聡、竹島秀幸、牛島俊和
    • Organizer
      第80回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-21H02773
  • [Presentation] ESCC cells with Gene A methylation show synthetic lethality with Gene B inhibition2021

    • Author(s)
      西山和宏、竹島秀幸、山下聡、小濱和貴、牛島俊和
    • Organizer
      第80回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-21H02773
  • [Presentation] Cancer epigenetics: mechanisms to clinical applications, and beyond2021

    • Author(s)
      牛島俊和
    • Organizer
      第80回日本癌学会学術総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21H02773
  • [Presentation] ESCC cells with Gene C methylation show synthetic lethality with Gene D knockdown2021

    • Author(s)
      Furuichi Yumi、Takeshima Hideyuki、Nishiyama Kazuhiro、Yamashita Satoshi、Okano Keiichi、Ushijima Toshikazu
    • Organizer
      第32回日本消化器癌発生学会総会
    • Data Source
      KAKENHI-PROJECT-21H02773
  • [Presentation] Low-dose DNA demethylating therapy induces reprogramming of specific cancer-related pathways at the single-cell level2021

    • Author(s)
      Takeshima Hideyuki、Yoda Yukie、Watanabe Naoko、Ushijima Toshikazu
    • Organizer
      第14回日本エピジェネティクス研究会年会
    • Data Source
      KAKENHI-PROJECT-18H02704
  • [Presentation] HSD17B4遺伝子のDNAメチル化は乳がん細胞の代謝的表現型を変化させる2021

    • Author(s)
      新井信晃、服部奈緒子、山下聡、向井博文、牛島俊和
    • Organizer
      第80回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-21H02773
  • [Presentation] Epigenetic field: Discovery to A Clinical Application2019

    • Author(s)
      牛島俊和
    • Organizer
      第78回日本癌学会学術総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02704
  • [Presentation] Identification of environmental factors that induce aberrant DNA methylation2019

    • Author(s)
      服部奈緒子、丹羽透、大河内(高田)江理子、今井俊夫、牛島俊和
    • Organizer
      第78回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-18H02704
  • [Presentation] LINC00162 Confers Sensitivity to 5-Aza-2’-deoxycytidine via Modulation of an RNA Splicing Protein, HNRNPH12018

    • Author(s)
      Yasukawa Y, Zong L, Hattori N, Mori A, Kimura K, Seto Y, Ushijima T
    • Organizer
      Post-A3 Meeting 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02704
  • [Presentation] LINC00162 Confers Sensitivity to 5-Aza-2’-deoxycytidine via Modulation of an RNA Splicing Protein, HNRNPH12018

    • Author(s)
      安川佳美、宗亮、服部奈緒子、瀬戸泰之、牛島俊和
    • Organizer
      第29回日本消化器癌発生学会総会
    • Data Source
      KAKENHI-PROJECT-18H02704
  • [Presentation] Gastric Cancer is Heavily Influenced by Aberrant DNA Methylation and Shows Sensitivity to DNA Demethylating Therapy2018

    • Author(s)
      牛島俊和、茂呂浩史、中村能章、服部奈緒子
    • Organizer
      第77回日本癌学会学術総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02704
  • [Presentation] Induction of an epigenetic field involving epithelial and stromal cells by chronic inflammation2017

    • Author(s)
      牛島 俊和、竹島 秀幸、前田 将宏
    • Organizer
      The 72nd Fujihara Seminar
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04302
  • [Presentation] Methylation burden and gastric cancer2017

    • Author(s)
      牛島 俊和
    • Organizer
      The 12th International Gastric Cancer Congress (IGCC)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04302
  • [Presentation] Vicious combination of dysregulated methylation machineries induced by chronic inflammation2017

    • Author(s)
      竹島 秀幸、丹羽 透、山下 聡、牛島 俊和
    • Organizer
      The 72nd Fujihara Seminar
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04302
  • [Presentation] 組織におけるエピゲノム傷害の程度は、発がん要因への曝露期間により決まる2017

    • Author(s)
      竹島 秀幸、丹羽 透、豊田 武士、山下 聡、牛島 俊和
    • Organizer
      第11回日本エピジェネティクス研究会年会
    • Data Source
      KAKENHI-PROJECT-15H04302
  • [Presentation] Induction of an epigenetic field involving epithelial and stromal cells by chronic inflammation2017

    • Author(s)
      牛島 俊和
    • Organizer
      France Japan Epigenetics Workshop 2017
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04302
  • [Presentation] Molecular mechanism of gastric carcinogenesis: for precision risk diagnosis and epigenetic therapy2017

    • Author(s)
      牛島 俊和
    • Organizer
      The 12th International Gastric Cancer Congress (IGCC)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04302
  • [Presentation] 炎症の悪い組み合わせは、DNA メチル化関連因子の制御異常を引き起こす2017

    • Author(s)
      竹島 秀幸、丹羽 透、山下 聡、牛島 俊和
    • Organizer
      第40回日本分子生物学会年会・第90回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-15H04302
  • [Presentation] エピジェネティック治療の重要性とさらなる応用拡大2017

    • Author(s)
      牛島 俊和
    • Organizer
      第15回日本臨床腫瘍学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H04302
  • [Presentation] 慢性炎症により誘発されるDNAメチル化装置制御異常の悪い組み合わせ2017

    • Author(s)
      竹島 秀幸、丹羽 透、山下 聡、若林 美香、牛島 俊和
    • Organizer
      第76回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-15H04302
  • [Presentation] 一件正常な細胞でのDNAメチル化異常の蓄積とがん発症2017

    • Author(s)
      牛島 俊和
    • Organizer
      日本薬学会第137年会
    • Place of Presentation
      仙台国際センター(宮城県仙台市)
    • Year and Date
      2017-03-24
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H04302
  • [Presentation] Vicious combination of dysregulated methylation machineries induced by chronic inflammation2017

    • Author(s)
      竹島 秀幸、丹羽 透、山下 聡、牛島 俊和
    • Organizer
      12th Asian Epigenomics Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04302
  • [Presentation] Field cancerization now gains ground2016

    • Author(s)
      牛島 俊和
    • Organizer
      第102回日本消化器病学会総会(第5回国際交流フォーラム)
    • Place of Presentation
      京王プラザホテル(東京都新宿区)
    • Year and Date
      2016-04-21
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04302
  • [Presentation] 性炎症による疾患におけるエピジェネティック異常の重要な役割2016

    • Author(s)
      牛島 俊和
    • Organizer
      第10回日本エピジェネティクス研究会年会
    • Place of Presentation
      千里ライフサイエンスセンター(大阪府豊中市)
    • Year and Date
      2016-05-19
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H04302
  • [Presentation] 慢性炎症によるTet遺伝子の発現抑制と異常DNAメチル化誘発2015

    • Author(s)
      竹島秀幸, 丹羽透, 若林美香, 山下聡, 牛島俊和
    • Organizer
      第30回発癌病理研究会
    • Place of Presentation
      オリビアン小豆島(香川県小豆郡)
    • Year and Date
      2015-08-26
    • Data Source
      KAKENHI-PROJECT-15H04302
  • [Presentation] Mechanisms of formation of epigenetic cancerization field by chronic inflammation2015

    • Author(s)
      Ushijima T
    • Organizer
      GRL Korea-Japan Epigenome Medicine Meeting 2015
    • Place of Presentation
      ダブルツリーbyヒルトン那覇(沖縄県那覇市)
    • Year and Date
      2015-05-17
    • Data Source
      KAKENHI-PROJECT-15H04302
  • [Presentation] The presence of strong target gene specificity in induction of DNA methylation, and its mechanisms.2009

    • Author(s)
      Ushijima, T.
    • Organizer
      Epigenetics in Development and Diseases Conference : 4th Asian Epigenomics Meeting.
    • Place of Presentation
      Singapore
    • Year and Date
      2009-08-25
    • Data Source
      KAKENHI-PROJECT-17013090
  • [Presentation] The presence of strong target gene specificity in induction of DNA methylation, and its mechanisms.2009

    • Author(s)
      Ushijima, T.
    • Organizer
      第68回日本癌学会学術総会International Session
    • Place of Presentation
      パシフィコ横浜(横浜)
    • Year and Date
      2009-10-03
    • Data Source
      KAKENHI-PROJECT-17012017
  • [Presentation] Instructive induction of aberrant DNA methylation, and epigenomic analysis of its underlying mechanisms.2009

    • Author(s)
      Ushijima T.
    • Organizer
      第32回日本分子生物学会年会シンポジウム
    • Place of Presentation
      横浜
    • Year and Date
      2009-12-10
    • Data Source
      KAKENHI-PROJECT-17013090
  • [Presentation] Instructive induction of aberrant DNA methylation, and epigenomic analysis of its underlying mechanisms.2009

    • Author(s)
      Ushijima T.
    • Organizer
      Epigenetics 2009 Australian Scientific Meeting.
    • Place of Presentation
      Melbourne
    • Year and Date
      2009-12-02
    • Data Source
      KAKENHI-PROJECT-17013090
  • [Presentation] The presence of strong target gene specificity in induction of DNA methylation, and its mechanisms.2009

    • Author(s)
      Ushijima T.
    • Organizer
      第68回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2009-10-03
    • Data Source
      KAKENHI-PROJECT-17013090
  • [Presentation] The presence of strong target gene specificity in induction of DNA methylation, and its mechanisms.2009

    • Author(s)
      Ushijima T.
    • Organizer
      Epigenetics in Development and Diseases Conference: 4th Asian Epigenomics Meeting.
    • Place of Presentation
      Singapore
    • Year and Date
      2009-08-25
    • Data Source
      KAKENHI-PROJECT-17013090
  • [Presentation] The presence of strong target gene specificity in induction of DNA methylation, and its mechanisms.2009

    • Author(s)
      Ushijima T.
    • Organizer
      18th Cancer Research Institute cancer symposium on "DNA and Histone Methylation in Cancer".
    • Place of Presentation
      Seoul
    • Year and Date
      2009-06-05
    • Data Source
      KAKENHI-PROJECT-17013090
  • [Presentation] DNA methylation induction by Helicobacter pylori infection in human gastric mucosae and target gene specificity.2008

    • Author(s)
      Nakajima, T., Yamashita, S., Maekita, T., Niwa, T., Nakazawa, K., and Ushijima, T.
    • Organizer
      67^<th> JCA meeting
    • Place of Presentation
      Nagoya
    • Year and Date
      2008-10-28
    • Data Source
      KAKENHI-PROJECT-17013090
  • [Presentation] Expression and methylation changes of APC 1A and 1B in gastric carcinogenesis.2008

    • Author(s)
      Hosoya K, Yamashita S, Ando T, Nakajima T, Nakanishi Y, Itoh F, Ushijima T.
    • Organizer
      67th JCA meeting.
    • Place of Presentation
      Nagoya
    • Year and Date
      2008-10-28
    • Data Source
      KAKENHI-PROJECT-17013090
  • [Presentation] Expression and methylation changes of APC 1A and 1B in gastric carcinogenesis.2008

    • Author(s)
      Hosoya, K., Yamashita, S., Ando, T., Nakajima, T., Nakanishi, Y., Itoh, F., and Ushijima, T.
    • Organizer
      67^<th> JCA meeting
    • Place of Presentation
      Nagoya
    • Year and Date
      2008-10-28
    • Data Source
      KAKENHI-PROJECT-17013090
  • [Presentation] DNA methylation induction by Helicobacter pylori infection in human gastric mucosae and target gene specificity.2008

    • Author(s)
      Nakajima T, Yamashita S, Maekita T, Niwa T, Nakazawa K, Ushijima T.
    • Organizer
      67th JCA meeting.
    • Place of Presentation
      Nagoya
    • Year and Date
      2008-10-28
    • Data Source
      KAKENHI-PROJECT-17013090
  • [Presentation] Epigenetic field defect for gastric cancers, and its use as a cancer risk marker.2007

    • Author(s)
      Ushijima T, Nakajima T.
    • Organizer
      The 11th Annual Meeting of Taiwan Cooperative Oncology Group.
    • Place of Presentation
      Taipei
    • Data Source
      KAKENHI-PROJECT-17013090
  • [Presentation] エピジェネティクスからみた多段階発がん2007

    • Author(s)
      牛島 俊和
    • Organizer
      日本エピジェネティクス研究会
    • Place of Presentation
      大阪府吹田市大阪大学コンベンションセンター
    • Year and Date
      2007-06-16
    • Data Source
      KAKENHI-PROJECT-17013090
  • [Presentation] Epigenetics in Cancers and Polyclonal Disorders2007

    • Author(s)
      牛島 俊和
    • Organizer
      日本薬物動態学会ビジョンシンポジウム
    • Place of Presentation
      東京都港区共立薬科大学
    • Year and Date
      2007-07-19
    • Data Source
      KAKENHI-PROJECT-17013090
  • [Presentation] エピジェネティックな発がんの場2007

    • Author(s)
      牛島 俊和
    • Organizer
      日本癌学会66回総会シンポジウム
    • Place of Presentation
      神奈川県横浜市パシフィコ横浜
    • Year and Date
      2007-10-05
    • Data Source
      KAKENHI-PROJECT-17013090
  • [Presentation] DNA methylation induction by Helicobacter pylori, and use as a cancer risk marker2007

    • Author(s)
      Ushijima, T.
    • Organizer
      The 19th Federation of Asian and Oceanian Biochemists and Molecular Biologists (FAOBMB) Conference
    • Place of Presentation
      Seoul(Korea)COEX Center
    • Year and Date
      2007-05-29
    • Data Source
      KAKENHI-PROJECT-17013090
  • [Presentation] Epigenetic field defect for gastric cancers, and its use as a cancer riskmarker2007

    • Author(s)
      Ushijima, T.
    • Organizer
      The llth Annual Meeting of Taiwan Cooperative Oncology Group
    • Place of Presentation
      Taipei (Taiwan) Howard International House
    • Year and Date
      2007-12-02
    • Data Source
      KAKENHI-PROJECT-17013090
  • [Presentation] DNA methylation as a marker for the past and future2007

    • Author(s)
      Ushijima, T.
    • Organizer
      The New Zealand Society for Oncology Conference
    • Place of Presentation
      Dunedin (NewZealand) Dunedin Centre
    • Year and Date
      2007-05-11
    • Data Source
      KAKENHI-PROJECT-17013090
  • [Presentation] Epigenetic field for cancerization2007

    • Author(s)
      Ushijima, T.
    • Organizer
      11th German-Japan Cancer Research Workshop
    • Place of Presentation
      Kyoto (Japan) Kvoto Garden Palace
    • Year and Date
      2007-11-29
    • Data Source
      KAKENHI-PROJECT-17013090
  • [Presentation] Environment-epigenome interaction2007

    • Author(s)
      Ushijima, T.
    • Organizer
      Symposium by Asian Network of Epigenomics
    • Place of Presentation
      Osaka (Japan) Institute for Protein Research
    • Year and Date
      2007-06-14
    • Data Source
      KAKENHI-PROJECT-17013090
  • [Presentation] 神経芽腫の強力予後因子としてのDNAメチル化2007

    • Author(s)
      牛島 俊和
    • Organizer
      小児癌学会・小児血液学会シンポジウム
    • Place of Presentation
      宮城県仙台市仙台国際センター
    • Year and Date
      2007-12-15
    • Data Source
      KAKENHI-PROJECT-17013090
  • [Presentation] Epigenetic field defect for gastric cancers2007

    • Author(s)
      Ushijima, T.
    • Organizer
      Gordon Research Conference
    • Place of Presentation
      Lucca (Italy) Il Ciocco
    • Year and Date
      2007-05-22
    • Data Source
      KAKENHI-PROJECT-17013090
  • [Presentation] Epigenetic field defect for gastric cancers.2007

    • Author(s)
      Ushijima T, Nakajima T, Enomoto S.
    • Organizer
      Gordon Research Conference.
    • Place of Presentation
      Il Ciocco
    • Data Source
      KAKENHI-PROJECT-17013090
  • [Presentation] Helicobacter pyloriによる胃粘膜でのDNAメチル化異常誘発2006

    • Author(s)
      牛島俊和
    • Organizer
      日本分子生物学会2006フォーラム
    • Data Source
      KAKENHI-PROJECT-17013090
  • [Presentation] A chemical genomic screening for methylation-silenced genes in gastric cancer cell lines using 5-aza-2'-deoxycytidine treatment and oligonucleotide microarray.2006

    • Author(s)
      Yamashita S, Tsujino Y, Moriguchi K, Tatematsu M, Ushijima T.
    • Organizer
      Annual Meeting of American Association for Cancer Research.
    • Place of Presentation
      Washington DC
    • Data Source
      KAKENHI-PROJECT-17013090
  • [Presentation] エピジェネティックな異常の起源と加速Helicobacter pyloriによるDNAメチル化異常誘発とCpGアイランド特異性2006

    • Author(s)
      牛島俊和
    • Organizer
      日本癌学会65回総会シンポジウム
    • Data Source
      KAKENHI-PROJECT-17013090
  • [Presentation] ヘリコバクター・ピロリ感染による異常dnaメチル化の高度の蓄積2005

    • Author(s)
      前北隆雄、中沢和之、中島健、三原真美、清水靖仁、杉村隆、斉藤大三、一瀬雅夫、牛島俊和
    • Organizer
      第64回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-17013090
  • 1.  OGAWA Katsuhiro (50045514)
    # of Collaborated Projects: 3 results
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  • 2.  長尾 美奈子 (40100151)
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  • 3.  YAMASHITA Sayoshi (80321876)
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  • 4.  ASADA Kiyoshi (50311410)
    # of Collaborated Projects: 2 results
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  • 5.  木南 凌 (40133615)
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  • 6.  中釜 斉 (30198030)
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  • 7.  竹島 秀幸 (40432497)
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  • 8.  山道 信毅 (30463897)
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  • 9.  冨田 秀太 (10372111)
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  • 10.  YAMAMURA Kenichi (90115197)
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  • 11.  YAMADA Gen (80174712)
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  • 16.  NAKO Kazuki (20217657)
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  • 18.  YAMAZAKI Yukiko (00239956)
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  • 21.  FUKAMACHI Hiroshi (70134450)
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  • 68.  元井 紀子
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  • 69.  新美 惠子
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