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Matsushita Osamu  松下 治

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MATSUSHITA Osamu  松下 治

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Researcher Number 00209537
Other IDs
Affiliation (Current) 2025: 愛媛県立医療技術大学, 保健科学部, 客員教授
Affiliation (based on the past Project Information) *help 2021 – 2023: 岡山大学, 医歯薬学域, 教授
2016 – 2022: 岡山大学, 医歯薬学総合研究科, 教授
2016: 岡山大学, 大学院医歯薬学総合研究科, 教授
2012 – 2016: 岡山大学, 医歯(薬)学総合研究科, 教授
2007 – 2012: Kitasato University School of Medicine, Department of Microbiology & Parasitology, Professor … More
2003 – 2006: Kagawa University(Faculty of Medicine), Molecular Microbiology, Assistant Professor, 医学部, 助教授
2004: Kagawa University, Molecular Microbiology, Associated professor, 医学部, 助教授
2002: 香川医大学, 医学部, 助教授
1999 – 2002: Kagawa Medical University, Microbiology, assistant professor, 医学部, 助教授
1996 – 1998: 香川医科大学, 医学部, 助手
1993 – 1994: 香川医科大学, 医学部, 助手
1991: Okayama University Medical School Department of Microbiology, Research Associate, 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
Bacteriology (including Mycology) / Bacteriology (including Mycology) / Basic Section 49050:Bacteriology-related / Bacteriology (including mycology)
Except Principal Investigator
Bacteriology (including Mycology) / Orthopaedic surgery / Basic Section 56020:Orthopedics-related / Bacteriology (including Mycology) / Basic Section 57030:Conservative dentistry-related / Basic Section 53010:Gastroenterology-related … More / Basic Section 55030:Cardiovascular surgery-related / Biomedical engineering/Biomaterial science and engineering / Neurochemistry/Neuropharmacology / 細菌学 / Plastic surgery / Biomedical engineering/Biological material science Less
Keywords
Principal Investigator
コラーゲン結合ドメイン / 細菌性コラゲナーゼ / collagen-binding domain / 再生医療 / 骨新生 / コラゲナーゼ / 細胞外マトリックス / 細菌毒素 / 構造活性相関 / ガス壊疽菌群 … More / Clostridium perfringens / clostridial collagenases / catalytic domain / 触媒ドメイン / beta-sandwitch / アンカリング / 技術移転 / アンカーリング / 膠原線維 / collagenase / 組織再生 / マトリックス・アンカリング / 薬物シーズ / バイオマーカー / 歯槽骨 / 構造生物学 / 多発性嚢胞腎(PKD) / 基質アンカー / 行動学的解析 / 組織学的解析 / 歯周病 / 神経再生 / 歯槽骨再生 / 基質アンカー・モジュール / osteoporosis / fusion protein / drug delivery system / parathyroid hormone / 薬物伝達システム / 骨粗鬆症 / 融合タンパク質 / 薬物送達システム / 副甲状腺ホルモン / substrate recognition / NMR analysis / 基質認識 / NMR解析 / conformational change / bacterial collagenases / Ca^<2+>依存性のコンフォメーション変化 / 新しいCa^<2+>結合モチーフ / β-サンドイッチ / コンフォメーション変換 / β-サンドイッチ構造 / collagenous peptide / Clostridium / コラーゲン様領域 / ベータ・サンドイッチ / クロストリジウム / trypsin / hippocampus / mouse lethality / lambda-toxin / epsilon-toxin / 組換え毒素 / ε毒素 / トリプシン / 海馬 / マウス致死活性 / λ-毒素 / ε-毒素 / ウエルシュ菌 / PKDドメイン / アンカーリンク / 重層扁平上皮 / 表皮成長因子 / スピン標識ペプチド / 血管新生 / 血管内皮細胞成長因子 / 鼓膜穿孔 / 上皮細胞成長因子 / 人工皮膚 / 鼓膜閉鎖術 / 成長因子 / 毒素 / コラーゲン / Clostridium histolyticum / 相同組換え / ストレス依存性チャネル / ウェルシュ菌 / metallo protease … More
Except Principal Investigator
Clostridium perfringens / 成長因子 / phased A-tracts / phospholipase C / 転写調節 / ホスホリパーゼC / ウエルシュ菌 / ウェルシュ菌 / Epsilon-toxin / Receptor / ε毒素 / bent DNA / コラーゲン結合型成長因子 / コラーゲン / 絞扼性神経障害 / 末梢神経障害 / 骨癒合 / LrpC / Bent DNA / イプシロン毒素 / 脂質ラフト / Histopathology / MDCK cell / Nephrotoxicity / Lipid rafts / NMDA / LTP / CaM kinase II / Epsilon-Toxin / RNA polymerase / RNAポリメラーゼ / 遺伝子発現 / DNA結合蛋白 / α毒素 / 細菌 / 塩基性線維芽細胞増殖因子 / 間葉系幹細胞 / 人工血管 / 融合タンパク / ベントDNA / バイオリアクター / フェレドキシン / ペプチド / マクロファージ / RAG2 KO / M2マクロファージ / T細胞サブセット / CD8 / T細胞 / 静脈 / 高密度コラーゲン / バイオミメティックベイン / vein wrapping / 絞扼性末梢神経傷害 / バイオミメティクス / Vein Wrapping / ドラッグデリバリーシステム / 増殖因子 / コラーゲン結合FGF-2 / コラーゲン結合型タンパク / 線維芽細胞増殖因子 / 歯周病 / 非臨床試験 / コラーゲン結合タンパク質 / 水平性骨吸収 / 歯周組織再生 / 胃炎 / 若年者 / 16SrDNA deep sequence法 / deep sequence法 / 16SrDNA / 糞便採取 / 大学新入生 / 青少年 / アルファ多様性分析 / ディスバイオシス / ヘリコバクター・ピロリ / dysbiosis / α多様性 / 除菌 / Helicobacter pylori / 若年成人 / 腸内細菌叢 / 骨形成蛋白 / ヒアルロン酸 / 難治性骨折 / 局所硬化ゲル / scaffold / collagen-binding domain / recellularization / decellularization / 心筋 / 小腸 / アンカリング / 脱細胞 / 機能的単心室症 / 細胞生着 / 脱細胞化 / 再生医療 / 拍動性グラフト / 先天性心疾患 / 組織工学 / 細胞・組織 / 移植・再生医療 / 後側方固定術 / 骨形成タンパク / 脊椎固定術 / 積層 / 細胞シート / コラーゲン結合蛋白 / 同種骨軟骨組織移植 / 骨軟骨移植 / 同種移植 / 組織保存 / 成長因子固相化 / 成長因子固相化技術 / 同種骨軟骨移植 / SNAP-25 / 疼痛抑制 / 神経障害性疼痛 / ボツリヌス神経毒素 / Gene expression / Transcriptional factor / イブシロン毒素 / co-crystallization / α subunit / regulation of transcription / 共結晶 / 共結晶化 / αサブユニット / Sphingomyelin / Ganglioside / Signal transduction / Platelet aggregation / Lipid raft / Alpha-toxin / セラミド / スフィンゴ糖脂質 / 脂質クラフト / 血小板 / スフィンゴミエリン / ガングリオシド / シグナル伝達 / 血小板凝集 / Immunohistochemsitry / 膜孔形成型毒素 / モノクローナル抗体 / 腸性毒素血症 / 構造解析 / Immunohistochemistry / Histoparhology / alcoholism / hypothermia / brain / S100 / calbrain / NMR / calcineurin / calmodulin-dependent protein kinase II / Ca^<2+> / 記憶 / カルシウム結合蛋白質 / アルコール依存症 / 低体温 / S-100 / 脳 / Calbrain / Membrane solubilization / Immunostaining / Synaptosome / Toxin complex / 膜可溶化 / 免疫染色 / シナプトソーム / 毒素複合体 / レセプター / transcriptional regulation / UPエレメント / Molecular biology / Bacterial toxin / Phospholipase C / Gene cloning / DNA-binding protein / 細菌の遺伝子発現 / 分子生物学 / 細菌毒素 / 遺伝子クローニング / DNA結合タンパク / gene regulation / DNA binding protein / alpha-toxin / C.peerfringens / Clostridium / 折れ曲がりDNA / Throat Swabs / Laboratory Diagnosis / Respiratory Exudates / DNA-probe Test / Latex Agglutination Test / Indirect Immunofluorescence Test / Mycoplasmal Pneumonia / Mycoplasma pneumonia / DNAプロ-ブ / Mycoplasma pheumoniae / DNA-プロ-ブ / ラテックス凝集反応 / 間接蛍光抗体法 / 臨床検査診断 / 咽頭スワブ / DNAプロ-ブ法 / ラテックス凝集法 / 間接螢光抗体法 / Mycoplasma pneumoniae / マイコプラズマ肺炎 / 融合蛋白 / VEGF-C / リンパ管再生 / リンパ浮腫 / リンパ管新生 / コラーゲン材料 / 再生医学 / 運動器再生 / コラーゲン結合ドメイン / 細菌コラゲナーゼ / 運動器再生医療 / 機能性人工骨膜 / 人工骨膜組織 / 細胞積層技術 / 人工骨膜 / 免疫不全マウス / アルブミン / HepG2細胞 / PEAC細胞 / CBD-cytokine / PLAシート / INTERGARD人工血管 / ePTFE人工血管 / PK15細胞 / 血管再生 / コラーゲン細線維 / 積層型高密度培養 / 細胞・組織工学 / 繊維芽細胞成長因子 / 副甲状腺ホルモン / 金属表面加工 / 関節機能再建術 / 組織移植 / 材料工学・処理 / Curved DNA / Phased A-tracts / Transcriptional fusion / Collagenase / Sialidase / Expression vector / Ferredoxin gene / コラゲナーゼ / シアリダーゼ / 発現ベクター / クロストリジウム / Clostridium perfringerns / pyruvate:ferredoxin酸化還元酵素 / 遺伝子投与 / 酪酸 / ヒドロゲナーゼ / ガス産生 / 水素ガス Less
  • Research Projects

    (39 results)
  • Research Products

    (136 results)
  • Co-Researchers

    (60 People)
  •  細菌性コラゲナーゼのドメイン協働機構解明とその分子基盤に基づく組織新生因子の創出Principal Investigator

    • Principal Investigator
      松下 治
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49050:Bacteriology-related
    • Research Institution
      Okayama University
  •  Identification of T Cell Subsets Involved in Constriction Nerve Injury and Development of Therapeutic Methods Using Neuropeptides

    • Principal Investigator
      Takaso Masashi
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      Kitasato University
  •  Establishment of biomimetic vein wrapping to treat chronic nerve injury

    • Principal Investigator
      Inoue Gen
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      Kitasato University
  •  Mechanism and control of collapse of gut microbiota caused by Helicobacter pylori eradication

    • Principal Investigator
      Okada Hiroyuki
    • Project Period (FY)
      2019 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Okayama University
  •  Development of periodontal tissue regeneration therapy for horizontal alveolar bone resorption with collagen-binding FGF-2

    • Principal Investigator
      Takashiba Shogo
    • Project Period (FY)
      2019 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 57030:Conservative dentistry-related
    • Research Institution
      Okayama University
  •  Elucidation of substrate recognition mechanism of bacterial collagenases to develop angiogenic drug seedsPrincipal Investigator

    • Principal Investigator
      Matsushita Osamu
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49050:Bacteriology-related
    • Research Institution
      Okayama University
  •  Development of a novel biomimetic vascular graft using original collagen anchoring domain with growth factor

    • Principal Investigator
      Kasahara Shingo
    • Project Period (FY)
      2018 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55030:Cardiovascular surgery-related
    • Research Institution
      Okayama University
  •  Delivery of Stem cell/growth factor using in situ-formed hydrogels for fracture repair

    • Principal Investigator
      Uchida Kentaro
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      Kitasato University
  •  Development of functional multilayered mesenchymal stem cells sheet for lumbar fusion surgery

    • Principal Investigator
      Inoue Gen
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Kitasato University
  •  Musculoskeletal regeneration using Growth factor-anchored materials

    • Principal Investigator
      Masashi Takaso
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Kitasato University
  •  Structure-function analysis of bacterial toxins in tissue destruction to apply their functional domains to regenerative medicinePrincipal Investigator

    • Principal Investigator
      MATSUSHITA Osamu
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Bacteriology (including mycology)
    • Research Institution
      Okayama University
  •  Development of collagen binding VEGF-C for lymphangiogenesis

    • Principal Investigator
      Matsumoto Hiroshi
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Plastic surgery
    • Research Institution
      Okayama University
  •  Clarification of molecular mechanisms underlying the analgesic effect of botulinum toxin and applied study

    • Principal Investigator
      YAMAMOTO YUMIKO
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biomedical engineering/Biomaterial science and engineering
    • Research Institution
      Okayama University
  •  Establishment of novel osteochondral allografting combined with growth factor- collagen-binding domain fusion technology

    • Principal Investigator
      Onuma Kenji
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Kitasato University
  •  Development of novel fracture healing methods using artificical perioteum and collagen-binding growth factor containing a collagen-binding domain from Clostridium histolyticum collagenase

    • Principal Investigator
      TAKASO Masashi
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Kitasato University
  •  Preclinical study to elucidate molecular mechanism of matrix anchoring using bacterial proteinsPrincipal Investigator

    • Principal Investigator
      MATSUSHITA Osamu
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      Okayama University
      Kitasato University
  •  Generating artificial parenchymal and hollow organs fabricated with collagen fibrils,various cells, and cytokines using a bioreactor that we have developed

    • Principal Investigator
      ADACHI Eijiro
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biomedical engineering/Biological material science
    • Research Institution
      Kitasato University
  •  Basic science technology study of new revision total hip arthroplasty using a fusion protein and the nanowire processing

    • Principal Investigator
      NARUSE Kouji
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Kitasato University
  •  Translational research on a drug delivery system using substrate binding domain derived from bacterial collagenasesPrincipal Investigator

    • Principal Investigator
      MATSUSHITA Osamu
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      Kitasato University
  •  A study on a mechanism for the transcriptional regulation of an epsilon-toxin gene by a novel type of bent DNA

    • Principal Investigator
      OKABE Akinobu
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      Kagawa University
  •  Interdisciplinary study on the calcium-dependent conformational change of collagen-binding domain from clostridial collagenasesPrincipal Investigator

    • Principal Investigator
      MATSUSHITA Osamu
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      Kitasato University
      Kagawa University
  •  A study on the molecular mechanism of substrate recognition by Clostridial collagenasesPrincipal Investigator

    • Principal Investigator
      MATSUSHITA Osamu
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      KAGAWA UNIVERSITY
  •  A study on the mechanism underlying the action of Clostridium perfringens alpha- and epsilon-toxins to membrane lipid rafts

    • Principal Investigator
      OKABE Akinobu
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      KAGAWA UNIVERSITY
      香川大学(医学部)
  •  Studies on the law temperature-dependent enhancement of transcription by a bent DNA

    • Principal Investigator
      KATAYAMA Seiichi
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      Faculty of Science, Okayama University of Science
  •  特殊ベント・プロモーターを利用した新規高発現ベクターの構築

    • Principal Investigator
      岡部 昭延
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      香川大学(医学部)
  •  Basic research on the development of novel vaccines with collagen-anchoring potency.Principal Investigator

    • Principal Investigator
      MATSUSHITA Osamu
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      Kagawa University(Faculty of Medicine)
  •  Study on structure biology and molecular pathology of Clostridium perfringens epsilon-toxin

    • Principal Investigator
      OKABE akinobu
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      Kagawa Medical University
  •  水素ガス産生用ウエルシュ菌バイオリアクター開発のための基礎研究

    • Principal Investigator
      OKABE Akinobu
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      香川医科大学
  •  Drug design based on the three-dimensional structure of collagen-binding domain, and its applicationPrincipal Investigator

    • Principal Investigator
      MATSUSHITA Osamu
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      香川医科大学
  •  Studies on neurotropism of Clostridium perfringens epsilon-toxin and molecular mechanism of its toxicity toward neuronal cells

    • Principal Investigator
      OKABE Akinobu
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      Kagawa Medical University
  •  Neuron specific calcium-binding Protein, calbrain, is involved in memory formation.

    • Principal Investigator
      TOKUDA Masaaki
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      KAGAWA MEDICAL UNIVERSITY
  •  Function of promoter upstream bent DNA of the Clostridium perfringens phospholipase C gene

    • Principal Investigator
      KATAYAMA Seiichi
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      Kagawa Medical University
  •  コラーゲン結合ドメインによるガス壊疸の発症予防Principal Investigator

    • Principal Investigator
      松下 治
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      香川医科大学
  •  Analysis of the activation and mode of action of Clostridium perfringens ε-toxinPrincipal Investigator

    • Principal Investigator
      MATSUSHITA Osamu, 南 純三朗
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      Kagawa Medical University
  •  ウェルシュ菌MSCLチャンネルによる病原遺伝子発現制御に関する研究Principal Investigator

    • Principal Investigator
      松下 治
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      香川医科大学
  •  Study on function of phospholipase C gene binding protein from Clostridium perfringens

    • Principal Investigator
      OKABE Akinobu
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      Kagawa Medical University
  •  ガス壊疽菌コラゲナーゼの反応機構の解析Principal Investigator

    • Principal Investigator
      松下 治
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      香川医科大学
  •  Function of protein (s) which can bind to an alpha-toxin gene of Clostridium perfringens

    • Principal Investigator
      OKABE Akinobu
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      Kagawa Medical School
  •  Developmental Studies on the Laboratory diagnosis at an early stage of Mycoplasam pneumoniae-infection (mycoplasmal pneumonia)

    • Principal Investigator
      KANEMASA Yasuhiro
    • Project Period (FY)
      1990 – 1991
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      細菌学
    • Research Institution
      Okayama University

All 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 Other

All Journal Article Presentation Patent

  • [Journal Article] コラーゲン結合型塩基性線維芽細胞増殖因子を用いた水平性骨吸収に対する歯周組織再生療法の開発2021

    • Author(s)
      中村心,伊東孝,岡本憲太郎,美間健彦,内田健太郎,山本直史,松下治,高柴正悟
    • Journal Title

      日本歯科医学会会誌

      Volume: 40 Pages: 78-78

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03831
  • [Journal Article] Acceleration of bone regeneration of horizontal bone defect in rats using collagen‐binding basic fibroblast growth factor combined with collagen scaffolds2019

    • Author(s)
      Nakamura Shin、Ito Takashi、Okamoto Kentaro、Mima Takehiko、Uchida Kentaro、Siddiqui Yasir D.、Ito Masahiro、Tai Masako、Okubo Keisuke、Yamashiro Keisuke、Omori Kazuhiro、Yamamoto Tadashi、Matsushita Osamu、Takashiba Shogo
    • Journal Title

      Journal of Periodontology

      Volume: - Issue: 9 Pages: 1-10

    • DOI

      10.1002/jper.18-0674

    • NAID

      120006860089

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K08830, KAKENHI-PROJECT-18K07111
  • [Journal Article] Polyglycolic acid‐collagen tube combined with collagen‐binding basic fibroblast growth factor accelerates gait recovery in a rat sciatic nerve critical‐size defect model2019

    • Author(s)
      Fujimaki Hisako、Uchida Kentaro、Inoue Gen、Matsushita Osamu、Nemoto Noriko、Miyagi Masayuki、Inage Kazuhide、Takano Shotaro、Orita Sumihisa、Ohtori Seiji、Tanaka Keisuke、Sekiguchi Hiroyuki、Takaso Masashi
    • Journal Title

      Journal of Biomedical Materials Research Part B: Applied Biomaterials

      Volume: 108 Issue: 2 Pages: 326-332

    • DOI

      10.1002/jbm.b.34391

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07111
  • [Journal Article] Ca2+-induced orientation of tandem collagen binding domains from clostridial collagenase ColG permits two opposing functions of collagen fibril formation and retardation.2018

    • Author(s)
      Caviness P, Bauer R, Tanaka K, Janowska K, Roeser JR, Harter D, Sanders J, Ruth C, Matsushita O, Sakon J.
    • Journal Title

      FEBS J.

      Volume: 285 Issue: 17 Pages: 3254-3269

    • DOI

      10.1111/febs.14611

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07111
  • [Journal Article] Oriented collagen tubes combined with basic fibroblast growth factor promote peripheral nerve regeneration in a 15 mm sciatic nerve defect rat model2017

    • Author(s)
      Fujimaki H, Uchida K, Inoue G, Miyagi M, Nemoto N, Saku T, Isobe Y, Inage K, Matsushita O, Yagishita S, Sato J, Takano S, Sakuma Y, Ohtori S, Takahashi K, Takaso M.
    • Journal Title

      J Biomed Mater Res A

      Volume: 105 Issue: 1 Pages: 8-14

    • DOI

      10.1002/jbm.a.35866

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26293341, KAKENHI-PROJECT-26460527, KAKENHI-PROJECT-15K20015
  • [Journal Article] Basic Fibroblast Growth Factor-Anchored Multilayered Mesenchymal Cell Sheets Accelerate Periosteal Bone Formation2017

    • Author(s)
      Uchida K, Inoue G, Matsushita O, Horikawa K, Sekiguchi H, Saito W, Takano S, Fujimaki H, Miyagi M, Takaso M.
    • Journal Title

      Biomed Res Int

      Volume: 4371460 Pages: 1-8

    • DOI

      10.1155/2017/4371460

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K10982, KAKENHI-PROJECT-17K10983, KAKENHI-PROJECT-17K16701, KAKENHI-PROJECT-15K20015
  • [Journal Article] Effect of Freeze-Dried Allograft Bone with Human Basic Fibroblast Growth Factor Containing a Collagen-Binding Domain From Clostridium Histolyticum Collagenase on Bone Formation After Lumbar Posterolateral Fusion Surgery in Rats2017

    • Author(s)
      Inoue G, Uchida K, Matsushita O, Fujimaki H, Saito W, Miyagi M, Sekiguchi H, Nishi N, Ohtori S, Yogoro M, Takaso M.
    • Journal Title

      Spine

      Volume: 印刷中 Issue: 17 Pages: 995-1001

    • DOI

      10.1097/brs.0000000000002074

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26293341, KAKENHI-PROJECT-26460527, KAKENHI-PROJECT-26861209, KAKENHI-PROJECT-15K20015, KAKENHI-PROJECT-17K10982, KAKENHI-PROJECT-17K16701
  • [Journal Article] Acceleration of bone formation during fracture healing by poly(pro-hyp-gly)10 and basic fibroblast growth factor containing polycystic kidney disease and collagen-binding domains from Clostridium histolyticum collagenase2016

    • Author(s)
      Sekiguchi H, Uchida K, Inoue G, Matsushita O, Saito W, Aikawa J, Tanaka K, Fujimaki H, Miyagi M, Takaso M.
    • Journal Title

      J Biomed Mater Res A

      Volume: 104 Issue: 6 Pages: 1372-1378

    • DOI

      10.1002/jbm.a.35670

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K20015, KAKENHI-PROJECT-26861209, KAKENHI-PROJECT-26861210, KAKENHI-PROJECT-26293341, KAKENHI-PROJECT-26460527
  • [Journal Article] Acceleration of callus formation during fracture healing using basic fibroblast growth factor-kidney disease domain-collagen binding domain fusion protein combined with allogenic demineralized bone powder.2015

    • Author(s)
      Saito W, Uchida K, Matsushita O, Inoue G, Sekiguchi H, Aikawa J, Fujimaki H, Takaso M.
    • Journal Title

      J Orthop Surg Res

      Volume: -

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26293341
  • [Journal Article] Cross-Excitation in Peripheral Sensory Ganglia Associated with Pain Transmission.2015

    • Author(s)
      Omoto K, Maruhama K, Terayama R, Yamamoto Y, Matsushita O, Sugimoto T, Oguma K, Matsuka Y
    • Journal Title

      Toxins (Basel)

      Volume: 7 Issue: 8 Pages: 2906-2917

    • DOI

      10.3390/toxins7082906

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26350499, KAKENHI-PROJECT-26293412
  • [Journal Article] Structures of three polycystic kidney disease-like domains from Clostridium histolyticum collagenases ColG and ColH.2015

    • Author(s)
      Bauer R, Janowska K, Taylor K, Jordan B, Gann S, Janowski T, Latimer EC, Matsushita O, Sakon J.
    • Journal Title

      Acta Crystallogr D Biol Crystallogr.

      Volume: 71 Issue: 3 Pages: 565-577

    • DOI

      10.1107/s1399004714027722

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26460527
  • [Journal Article] Enhancement of periosteal bone formation by basic fibroblast-derived growth factor containing polycystic kidney disease and collagen-binding domains from Clostridium histolyticum collagenase.2015

    • Author(s)
      Uchida K, Matsushita O, Nishi N, Inoue G, Horikawa K, Takaso M. .
    • Journal Title

      J Tissue Eng Regen Med

      Volume: in press Issue: 4 Pages: 1165-1172

    • DOI

      10.1002/term.2019

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24791560, KAKENHI-PROJECT-25670659, KAKENHI-PROJECT-26293341
  • [Journal Article] Acceleration of callus formation during fracture healing using basic fibroblast growth factor-kidney disease domain-collagen-binding domain fusion protein combined with allogenic demineralized bone powder.2015

    • Author(s)
      Saito W, Uchida K, Matsushita O, Inoue G, Sekiguchi H, Aikawa J, Fujimaki H, Takaso M.
    • Journal Title

      J Orthop Surg Res.

      Volume: 10 Issue: 1 Pages: 59-59

    • DOI

      10.1186/s13018-015-0201-0

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26460527, KAKENHI-PROJECT-26861210
  • [Journal Article] Acceleration of callus formation during fracture healing using basic fibroblast growth factor-kidney disease domain-collagen binding domain fusion protein combined with allogenic demineralized bone powder.2015

    • Author(s)
      Saito W, Uchida K, Matsushita O, Inoue G, Sekiguchi H, Aikawa J, Fujimaki H, Takaso M.
    • Journal Title

      J Orthop Surg Res

      Volume: -

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25670659
  • [Journal Article] Treatment and prevention of chemotherapy-induced alopecia with PTH-CBD, a collagen-targeted parathyroid hormone analog, in a non-depilated mouse model2014

    • Author(s)
      Katikaneni R, Ponnapakkam T, MatsushitaO, Sakon J, Gensure R
    • Journal Title

      Anticancer Drugs

      Volume: 25(1) Issue: 1 Pages: 30-38

    • DOI

      10.1097/cad.0b013e3283650bff

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590516
  • [Journal Article] Acceleration of periosteal bone formation by human basic fibroblast growth factor containing a collagen-binding domain from Clostridium histolyticum collagenase.2014

    • Author(s)
      Uchida K, Matsushita O, Naruse K, Mima T, Nishi N, Hattori S, Ogura T, Inoue G, Tanaka K, Takaso M.
    • Journal Title

      J Biomed Mater Res A.

      Volume: 102 Issue: 6 Pages: 1737-1743

    • DOI

      10.1002/jbm.a.34841

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590516, KAKENHI-PROJECT-23790483, KAKENHI-PROJECT-24791560, KAKENHI-PROJECT-25670659, KAKENHI-PROJECT-26460527, KAKENHI-PROJECT-26861210
  • [Journal Article] Acceleration of bone union after structural bone grafts with a collagen-binding basic fibroblast growth factor anchored-collagen sheet for critical-size bone defects.2014

    • Author(s)
      Ueno M, Uchida K, Saito W, Matsushita O, Yogoro M, Nishi N, Ogura T, Hattori S, Inoue G, Tanaka K, Takahira N, Takaso M.
    • Journal Title

      Biomed Mater.

      Volume: 9 Issue: 3 Pages: 035014-035014

    • DOI

      10.1088/1748-6041/9/3/035014

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26460527, KAKENHI-PROJECT-26861210
  • [Journal Article] Direct cytocidal effect of galectin-9 localized on collagen matrices on human immune cell lines.2014

    • Author(s)
      Fukata Y, Itoh A, Nonaka Y, Ogawa T, Nakamura T, Matsushita O, Nishi N.
    • Journal Title

      Biochim Biophys Acta

      Volume: 1840 Issue: 6 Pages: 1892-1901

    • DOI

      10.1016/j.bbagen.2014.01.019

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590516, KAKENHI-PROJECT-26460527
  • [Journal Article] Structural comparison of ColH and ColG collagen-binding domains from Clostridium histolyticum.2013

    • Author(s)
      Bauer R, Wilson JJ, Philominathan ST, Davis D, Matsushita O, Sakon J.
    • Journal Title

      J Bacteriol.

      Volume: 195 Issue: 2 Pages: 318-327

    • DOI

      10.1128/jb.00010-12

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590516
  • [Journal Article] Effects of CB-VEGF-A Injection in Rat Flap Models for Improved Survival.2013

    • Author(s)
      Akimoto M, Takeda A, Matsushita O, Inoue J, Sakamoto K, Hattori M, Kounoike N, Uchinuma E.
    • Journal Title

      Plast Reconstr Surg.

      Volume: 131 Issue: 4 Pages: 717-725

    • DOI

      10.1097/prs.0b013e3182818b34

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590516
  • [Journal Article] Acceleration of bone formation during fracture healing by injectable collagen powder and human basic fibroblast growth factor containing a collagen-binding domain from Clostridium histolyticum collagenase2013

    • Author(s)
      Saito W, Uchida K, Ueno M, MatsushitaO, Inoue G, Nishi N, Ogura T, Hattori S, Fujimaki H, Tanaka K, Takaso M
    • Journal Title

      J Biomed Mater Res A

      Volume: in press Issue: 9 Pages: 3049-3055

    • DOI

      10.1002/jbm.a.34974

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590516, KAKENHI-PROJECT-24791560, KAKENHI-PROJECT-25670659, KAKENHI-PROJECT-26460527, KAKENHI-PROJECT-26861210
  • [Journal Article] A single injection of the anabolic bone agent, parathyroid hormone-collagen binding domain (PTH-CBD), results in sustained increases in bone mineral density for up to 12 months in normal female mice.2012

    • Author(s)
      Ponnapakkam T, Katikaneni R, Suda H, Miyata S, Matsushita O, Sakon J, Gensure RC.
    • Journal Title

      Calcif Tissue Int.

      Volume: 91 Issue: 3 Pages: 196-203

    • DOI

      10.1007/s00223-012-9626-1

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590516, KAKENHI-PROJECT-24590538
  • [Journal Article] Bacterial collagen-binding domain targets undertwisted regions of collagen.2012

    • Author(s)
      Philominathan ST, Koide T, Matsushita O, Sakon J.
    • Journal Title

      Protein Sci.

      Volume: 21 Issue: 10 Pages: 1554-1565

    • DOI

      10.1002/pro.2145

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590516
  • [Journal Article] Treatment for chemotherapy-induced alopecia in mice using parathyroid hormone agonists and antagonists linked to a collagen binding domain.2012

    • Author(s)
      Katikaneni R, Ponnapakkam T, Suda H, Miyata S, Sakon J, Matsushita O, Gensure RC.
    • Journal Title

      Int J Cancer

      Volume: 131 Issue: 5

    • DOI

      10.1002/ijc.27379

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590516
  • [Journal Article] Probing the 3-D structure, dynamics, and stability of bacterial collagenase collagen binding domain (apo- versus holo-) by limited proteolysis MALDI-TOF MS2012

    • Author(s)
      Sides CR, Liyanage R, Lay JO Jr, Philominathan ST, Matsushita O, Sakon J
    • Journal Title

      J Am Soc Mass Spectrom

      Volume: 23(3) Issue: 3 Pages: 505-519

    • DOI

      10.1007/s13361-011-0309-3

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590516
  • [Journal Article] Prevention of chemotherapy-induced osteoporosis by cyclophosphamide with a long-acting form of parathyroid hormone.2011

    • Author(s)
      Ponnapakkam T, Katikaneni R, Nichols T, Tobin G, Sakon J, Matsushita O, Gensure RC.
    • Journal Title

      J. Endocrinol. Invest.

      Volume: 34

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590516
  • [Journal Article] Monthly administration of a novel PTH-vollagen binding domain fusion protein is anabolic in mice. Calcif.2011

    • Author(s)
      Ponnapakkam T., Katikaneni, R., Miller, E., Ponnapakkam, A., Suda, H., Miyata, S., Suva, L.J., JSakon, J., Matsushita, O., Gensure, R.C.
    • Journal Title

      Tissue Int. in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590452
  • [Journal Article] Monthly administration of a novel PTH-collagen binding domain fusion protein is anabolic in mice2011

    • Author(s)
      Ponnapakkam Tulasi, 他9名
    • Journal Title

      Calcif Tissue Int

      Volume: 88 Issue: 6 Pages: 511-520

    • DOI

      10.1007/s00223-011-9485-1

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22300167, KAKENHI-PROJECT-23590516
  • [Journal Article] Prevention of chemotherapy-induced osteoporosis by cyclophosphamide with a long-acting form of parathyroid hormone2011

    • Author(s)
      Ponnapakkam T, Katikaneni R, Nichols T, Tobin G, Sakon J, Matsushita O, Gensure RC
    • Journal Title

      J Endocrinol Invest

      Volume: 34(11)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590516
  • [Journal Article] Unidirectional binding of clostridial collagenase to triple helical substrates.2009

    • Author(s)
      Philominathan, S.T., Koide, T., Hamada, K., Yasui, H., Seifert, S., Matsushita, O., Sakon, J.
    • Journal Title

      J.Biol.Chem. 284

      Pages: 10868-10876

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590452
  • [Journal Article] Development of a high-throughput screening system for the compounds that inhibit collagen-protein interactions.2009

    • Author(s)
      Okano-Kosugi H, Matsushita O, Asada S, Herr AB, Kitagawa K, Koide T.
    • Journal Title

      Anal.Biochem. 394

      Pages: 125-131

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590452
  • [Journal Article] Unidirectional binding of clostridial collagenase to triple helical substrates.2009

    • Author(s)
      Philominathan ST, Koide T, Hamada K, Yasui H, Seifert S, Matsushita O, Sakon J.
    • Journal Title

      J.Biol.Chem. 284

      Pages: 10868-10876

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590452
  • [Journal Article] Ca^<2+>-induced linker transformation leads to a compact and rigid collagen-binding domain of Clostridium histolyticum collagenase.2009

    • Author(s)
      Philominathan ST, Matsushita O, Gensure R, Sakon J.
    • Journal Title

      FEBS J. 276

      Pages: 3589-3601

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590452
  • [Journal Article] Development of a high-throughput screening system for the compounds that inhibit collagen-protein interactions.2009

    • Author(s)
      Okano-Kosugi, H., Matsushita, O., Asada, S., Herr, A.B., Kitagawa, K., Koide, T.
    • Journal Title

      Anal.Biochem. 394

      Pages: 125-131

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590452
  • [Journal Article] Ca2^+-induced linker transformation leads to a compact and rigid collagen-binding domain of Clostridium histolyticum collagenase.2009

    • Author(s)
      Philominathan, S.T., Matsushita, O., Gensure, R., Sakon, J.
    • Journal Title

      FEBS J. 276

      Pages: 3589-3601

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590452
  • [Journal Article] High-level expression of his-tagged clostridial collagenase in Clostridium perfringens.2008

    • Author(s)
      Tamai, E., Miyata, S., Tanaka, H., Nariya, H., Suzuki, M., Matsushita, O., Hatano, N., Okabe, A.
    • Journal Title

      Appl. Microbiol. Biotechnol. 80

      Pages: 627-635

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590452
  • [Journal Article] High-level expression of his-tagged clostridial collagenase in Clostridium perfringens.2008

    • Author(s)
      Tamai, E., Miyata, S., Tanaka, H., Nariya, H., Suzuki,M., Matsushita, O., Hatano, N., Okabe, A.
    • Journal Title

      Appl.Microbiol.Biotechnol. 80

      Pages: 627-635

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590452
  • [Journal Article] ^1H,^<13>C and ^<15>N resonace assignments of Ca^<2+> bound collagen-binding domain derived from a clostridial collagenase2008

    • Author(s)
      Philominathan, S. T. L., Matsushita, O., Jordan, J. B., Sakon, J.
    • Journal Title

      Biomol. NMR Assign. 2

      Pages: 127-129

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590452
  • [Journal Article] 1H, 13C and 15N resonace assignments of Ca2^+-bound collagen-binding domain derived from a clostridial collagenase.2008

    • Author(s)
      Philominathan, S.T.L., Matsushita, O., Jordan, J.B., Sakon, J.
    • Journal Title

      Biomol.NMR Assign. 2

      Pages: 127-129

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590452
  • [Journal Article] Changens in ganglioside content affect the binding of Clostridium perfringens epsilon-toxin to detergent-resistant membranes of Madin-Darby canine kidney cells.2005

    • Author(s)
      Shimamoto S, Tamai E, Matsushita O, Minami J, Okabe A, Miyata S.
    • Journal Title

      Microbiology and Immunology 49(3)

      Pages: 245-253

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390144
  • [Patent] Release of Growth Factors at Wound Healing Stages2021

    • Inventor(s)
      J Sakon, O Matsushita, 他3名
    • Industrial Property Rights Holder
      アーカンソー大学、岡山大学
    • Industrial Property Rights Type
      特許
    • Filing Date
      2021
    • Overseas
    • Data Source
      KAKENHI-PROJECT-18K07111
  • [Patent] コラーゲン結合タンパク質による治療剤の送達2020

    • Inventor(s)
      サコン ジョシュア、松下 治、他6名
    • Industrial Property Rights Holder
      アーカンソー大学、北里研究所、他2法人
    • Industrial Property Rights Type
      特許
    • Patent Publication Number
      2020-073554
    • Filing Date
      2020
    • Data Source
      KAKENHI-PROJECT-18K07111
  • [Patent] FUSION PROTEINS OF COLLAGEN-BINDING DOMAIN AND PARATHYROID HORMONE2019

    • Inventor(s)
      Gensure, Sakon, 松下, Ponnapakkam
    • Industrial Property Rights Holder
      U Ark, Ochsner Clinic, Kagawa U
    • Industrial Property Rights Type
      特許
    • Filing Date
      2019
    • Acquisition Date
      2019
    • Overseas
    • Data Source
      KAKENHI-PROJECT-18K07111
  • [Patent] Collagen-binding agent compositions and methods of using same2017

    • Inventor(s)
      O Matsushita, K Uchida, J Sakon他
    • Industrial Property Rights Holder
      U Arkansas, Kitasato U.
    • Industrial Property Rights Type
      特許
    • Filing Date
      2017-02-10
    • Overseas
    • Data Source
      KAKENHI-PROJECT-26460527
  • [Patent] コラーゲン結合領域と副甲状腺ホルモンとの融合タンパク2015

    • Inventor(s)
      松下 治、サコン ジョシュア他
    • Industrial Property Rights Holder
      アーカンソー大学、香川大学、オクスナー クリニック
    • Industrial Property Rights Type
      特許
    • Filing Date
      2015-09-03
    • Acquisition Date
      2016-09-07
    • Data Source
      KAKENHI-PROJECT-26460527
  • [Patent] 神経再生用移植材料、神経再生用移植材料の製造方法、及び神経再生用移植材料製造用キット2015

    • Inventor(s)
      内田健太郎、井上玄、藤巻寿子、高相晶士、松下治
    • Industrial Property Rights Holder
      内田健太郎、井上玄、藤巻寿子、高相晶士、松下治
    • Industrial Property Rights Type
      特許
    • Filing Date
      2015-10-16
    • Overseas
    • Data Source
      KAKENHI-PROJECT-26293341
  • [Patent] 神経再生用移植材料、神経再生用移植材料の製造方法、及び神経再生用移植材料製造用キット2015

    • Inventor(s)
      内田,井上,藤巻,高相,佐久,礒部,松下,美間,西,服部,田中他
    • Industrial Property Rights Holder
      北里研究所、香川大学、株)アトリー、株)ニッピ
    • Industrial Property Rights Type
      特許
    • Filing Date
      2015-10-16
    • Overseas
    • Data Source
      KAKENHI-PROJECT-26460527
  • [Patent] Fusion proteins of collagen-binding domain and parathyroid hormone2015

    • Inventor(s)
      J Sakon, O Matsushita他
    • Industrial Property Rights Holder
      Ochsner, Kagawa U, U Arkansas
    • Industrial Property Rights Type
      特許
    • Filing Date
      2015-06-18
    • Acquisition Date
      2016-12-27
    • Overseas
    • Data Source
      KAKENHI-PROJECT-26460527
  • [Patent] 神経再生用移植材料、神経再生用移植材料の製造方法、及び神経再生用移植材料製造用キット.2014

    • Inventor(s)
      内田健太郎 井上 玄、高相晶士、松下 治 他8名
    • Industrial Property Rights Holder
      内田健太郎 井上 玄、高相晶士、松下 治 他8名
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2014-212085
    • Filing Date
      2014-10-16
    • Data Source
      KAKENHI-PROJECT-26293341
  • [Patent] Fusion protein of collagen-binding domain and parathyroid hormone2013

    • Inventor(s)
      O.Matsushita, R. C. Gensure, and J. Sakon
    • Industrial Property Rights Holder
      The Board of Trustees of the University of Arkansas, Ochsner Clinic Foundation, National University Corporation Kagawa University
    • Industrial Property Rights Type
      特許
    • Filing Date
      2013-05-28
    • Data Source
      KAKENHI-PROJECT-23590516
  • [Patent] 成長因子アンカーリング型骨移植材料、成長因子アンカーリング型骨移植材料の製造方法、成長因子アンカーリング型骨移植材料製造用キット、および骨形成方法2012

    • Inventor(s)
      内田健太郎、成瀬康治、高相晶士、美間健彦、松下治、他2名
    • Industrial Property Rights Holder
      国立大学法人香川大学、学校法人北里研究所
    • Industrial Property Rights Type
      特許
    • Filing Date
      2012-03-26
    • Data Source
      KAKENHI-PROJECT-23590516
  • [Patent] 成長因子アンカーリング型骨移植材料、成長因子アンカーリング型膏移植材料の製造方法、成長因子アンカーリング型骨移植材料製造用キット、および骨形成方法2012

    • Inventor(s)
      内田健太郎、成瀬康治、高相晶士、美間健彦、松下治、原口高志、西望
    • Industrial Property Rights Holder
      北里大学、香川大学
    • Filing Date
      2012-03-26
    • Overseas
    • Data Source
      KAKENHI-PROJECT-21591923
  • [Patent] 成長因子アンカーリング型骨移植材料、成長因子アンカーリング型骨移植材料の製造方法、成長因子アンカーリング型骨移植材料製造用キット、および骨形成方法2012

    • Inventor(s)
      内田健太郎、成瀬康治、高相晶士、美間健彦、松下治、他2名
    • Industrial Property Rights Holder
      香川大学、北里大学
    • Filing Date
      2012
    • Overseas
    • Data Source
      KAKENHI-PROJECT-23590516
  • [Patent] 成長因子アンカーリング型骨移植材料、成長因子アンカーリング型骨移植材料の製造方法、成長因子アンカーリング型骨移植材料製造用キット、および骨形成方法2012

    • Inventor(s)
      内田健太郎、成瀬康治、高相晶士、美間健彦、松下治、原口高志、西望
    • Industrial Property Rights Holder
      北里大学、香川大学
    • Industrial Property Number
      2011-108650
    • Filing Date
      2012-03-26
    • Data Source
      KAKENHI-PROJECT-21591923
  • [Patent] 成長因子アンカーリング型骨移植材料2011

    • Inventor(s)
      内田健太郎、成瀬康治、高相晶士、美間健彦、松下治、原口高志、西望
    • Industrial Property Rights Holder
      学校法人北里研究所、国立大学法人香川大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2011-108650
    • Filing Date
      2011-05-13
    • Overseas
    • Data Source
      KAKENHI-PROJECT-23590516
  • [Patent] 成長因子アンカーリング型骨移植材料2011

    • Inventor(s)
      内田健太郎、成瀬康治、高相晶士、美間健彦、松下治、他2名
    • Industrial Property Rights Holder
      香川大学、北里大学
    • Industrial Property Number
      2011-108650
    • Filing Date
      2011
    • Data Source
      KAKENHI-PROJECT-23590516
  • [Patent] 上皮層含有組織の再生材および再生評価方法2011

    • Inventor(s)
      宮下武憲、森 望、西 望、安達栄治郎、松下 治、服部雅一、他2名
    • Industrial Property Rights Holder
      香川大学、北里大学
    • Filing Date
      2011
    • Overseas
    • Data Source
      KAKENHI-PROJECT-23590516
  • [Patent] 成長因子アンカーリング型骨移植材料、成長因子アンカーリング型骨移植材料の製造方法、成長因子アンカーリング型骨移植材料製造用キット.および骨形成方法2011

    • Inventor(s)
      内田健太郎、成瀬康治、高相晶士、美間健彦、松下治、原口高志、西望
    • Industrial Property Rights Holder
      北里大学、香川大学
    • Industrial Property Number
      2011-108650
    • Filing Date
      2011-05-12
    • Data Source
      KAKENHI-PROJECT-21591923
  • [Patent] 成長因子アンカーリング型骨移植材料、成長因子アンカーリング型骨移植材料の製造方法、成長因子アンカーリング型骨移植材料製造用キット、および骨形成方法2011

    • Inventor(s)
      内田健太郎、成瀬康治、高相晶士、美間健彦、松下治、原口高志、西望
    • Industrial Property Rights Holder
      北里大学、香川大学
    • Filing Date
      2011-05-12
    • Overseas
    • Data Source
      KAKENHI-PROJECT-21591923
  • [Patent] 上皮層含有組織の再生材および再生評価方法2011

    • Inventor(s)
      宮下武憲、森望、西望、安達栄治郎、松下治、服部雅一、他2名
    • Industrial Property Rights Holder
      国立大学法人香川大学、学校法人北里研究所
    • Industrial Property Rights Type
      特許
    • Filing Date
      2011-05-12
    • Data Source
      KAKENHI-PROJECT-23590516
  • [Patent] 積層型高密度培養人工組織の製造方法及び積層型高密度培養人工組織2010

    • Inventor(s)
      安達栄治郎、松下治、岩城啓修、細谷智、西望
    • Industrial Property Rights Holder
      学校法人北里研究所・国立大学法人香川大学
    • Filing Date
      2010-01-28
    • Overseas
    • Data Source
      KAKENHI-PROJECT-20590452
  • [Patent] 粘膜、上皮および鼓膜の少なくとも一つの再生材および再生評価法2010

    • Inventor(s)
      宮下武憲, 森望, 西望, 安達栄治郎, 松下治, 服部雅一, 伊藤周平, 坂本恵子
    • Industrial Property Rights Holder
      国立大学法人香川大学、学校法人北里研究所
    • Industrial Property Number
      2010-110694
    • Filing Date
      2010-05-12
    • Data Source
      KAKENHI-PROJECT-22300167
  • [Patent] 粘膜、上皮および鼓膜の少なくとも一つの再生材および再生評価方法2010

    • Inventor(s)
      宮下武憲、森望、西望、安達栄治郎、松下治、服部雅一、伊藤周平、坂本恵子
    • Industrial Property Rights Holder
      国立大学法人香川大学、学校法人北里研究所
    • Industrial Property Number
      2010-110694
    • Filing Date
      2010-05-12
    • Data Source
      KAKENHI-PROJECT-20590452
  • [Patent] 粘膜、上皮および鼓膜の少なくとも-つの再生材および再生評価方法2010

    • Inventor(s)
      宮下武憲、森望、西望、安達栄治郎、松下治、服部雅一、伊藤周平、坂本恵子
    • Industrial Property Rights Holder
      香川大学 北里大学
    • Industrial Property Number
      2010-110694
    • Filing Date
      2010-05-12
    • Data Source
      KAKENHI-PROJECT-20590452
  • [Patent] 積層型高密度培養人工組織の製造方法及び積層型高密度培養人工組織2010

    • Inventor(s)
      安達栄治郎、松下治、岩城啓修、細谷智、西望
    • Industrial Property Rights Holder
      学校法人北里研究所、国立大学法人香川大学
    • Filing Date
      2010-01-28
    • Overseas
    • Data Source
      KAKENHI-PROJECT-20590452
  • [Patent] 粘膜、上皮および鼓膜の少なくとも一つの再生材および再生評価法2010

    • Inventor(s)
      宮下武憲、森望、西望、安達栄治郎、松下治、服部雅一、伊藤周平、坂本恵子
    • Industrial Property Rights Holder
      国立大学法人香川大学、学校法人北里研究所
    • Industrial Property Number
      2010-110694
    • Filing Date
      2010-05-12
    • Data Source
      KAKENHI-PROJECT-22300167
  • [Patent] 積層型高密度培養人工組織の製造方法及び積層型高密度培養人工組織2009

    • Inventor(s)
      安達栄治郎、松下治、岩城啓修、細谷智、西望
    • Industrial Property Rights Holder
      学校法人北里研究所、国立大学法人香川大学
    • Industrial Property Number
      2009-017475
    • Filing Date
      2009-01-19
    • Data Source
      KAKENHI-PROJECT-20590452
  • [Patent] 積層型高密度培養人工組織の製造方法及び積層型高密度培養人工組織2009

    • Inventor(s)
      安達栄治郎, 松下治, 岩城啓修, 細谷 智, 西 望
    • Industrial Property Rights Holder
      学校法人北里研究所, 国立大学法人香川大学
    • Industrial Property Number
      2009-017475
    • Filing Date
      2009-01-19
    • Data Source
      KAKENHI-PROJECT-20590452
  • [Patent] Fusion Protein of Collagen-binding domain and parathyroid hormone2007

    • Inventor(s)
      Osamu Matsushita, Robert C.Gensure, and Joshua Sakon
    • Industrial Property Rights Holder
      Kagawa University, University of Arkansas, OCHSNER Health System
    • Filing Date
      2007-04-09
    • Description
      「研究成果報告書概要(和文)」より
    • Overseas
    • Data Source
      KAKENHI-PROJECT-18590429
  • [Patent] Fusion Protein of Collagen-binding domain and parathyroid hormone2007

    • Inventor(s)
      Osamu Matsushita, Robert C.Gensure, and Joshua Sakon
    • Industrial Property Rights Holder
      Kagawa University, University of Arkansas, OCHSNER Health System
    • Filing Date
      2007-04-09
    • Overseas
    • Data Source
      KAKENHI-PROJECT-18590429
  • [Patent] Fusion Protein of Collagen-binding Protein and PTH

    • Inventor(s)
      Osamu Matsushita, Joshua Sakon, Fobert C.Gensure
    • Industrial Property Rights Holder
      Kagawa University, University of Arkansas, OCHSNER Health System
    • Data Source
      KAKENHI-PROJECT-18590429
  • [Presentation] 細菌性コラゲナーゼ由来コラーゲン・アンカーの構造活性相関と神経再生への応用2021

    • Author(s)
      松下 治、美間健彦、後藤和義、山本由弥子、Perry Caviness、Joshua Sakon、内田健太郎、藤巻寿子、井上 玄、高相晶士
    • Organizer
      第94回日本細菌学会総会
    • Data Source
      KAKENHI-PROJECT-18K07111
  • [Presentation] コラーゲン結合型塩基性線維芽細胞増殖因子を用いた水平性骨吸収に対する歯周組織再生療法の開発2021

    • Author(s)
      中村心,伊東孝,岡本憲太郎,美間健彦,内田健太郎,松下治,高柴正悟
    • Organizer
      第36回「歯科医学を中心とした総合的な研究を推進する集い(令和2年度)
    • Data Source
      KAKENHI-PROJECT-19H03831
  • [Presentation] 細菌性コラゲナーゼのコラーゲン・アンカーと歯周組織治療への応用2020

    • Author(s)
      松下 治、美間健彦、後藤和義、山本由弥子、Perry Caviness、Joshua Sakon、中村 心、岡本健太郎、高柴正悟
    • Organizer
      第93回日本細菌学会総会
    • Data Source
      KAKENHI-PROJECT-18K07111
  • [Presentation] Collagen-binding basic fibroblast growth factor regenerates horizontal alveolar bone defect2019

    • Author(s)
      Nakamura S, Ito T, Okamoto K, Mima T, Uchida K, Siddiqui YD, Ito M, Tai M, Okubo K, Yamashiro K, Omori K, Yamamoto T, Matsushita O, Takashiba S
    • Organizer
      97th International Association of Dental Research, General Session & Exhibition
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03831
  • [Presentation] 細菌性コラゲナーゼのコラーゲン・アンカーと歯周組織再生への応用2019

    • Author(s)
      松下 治、美間健彦、後藤和義、山本由弥子、Perry Caviness、Joshua Sakon、小出隆規、内田健太郎、中村 心、高柴正悟
    • Organizer
      第92回日本細菌学会総会
    • Data Source
      KAKENHI-PROJECT-18K07111
  • [Presentation] コラーゲン結合型塩基性線維芽細胞成長因子はコラーゲン基剤からの徐放によって歯周組織再生を促進する2019

    • Author(s)
      岡本憲太郎,中村心,伊東孝,Yasir Dilshad Siddiqui,美間健彦,内田健太郎,大森一弘,山本直史,松下治,高柴正悟
    • Organizer
      第150回日本歯科保存学会2019年度春季学術大会
    • Data Source
      KAKENHI-PROJECT-19H03831
  • [Presentation] 悪玉クロストリジウムの毒素を薬に2019

    • Author(s)
      松下 治
    • Organizer
      第2回岡山消化器学術講演会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K07111
  • [Presentation] コラーゲン材料とコラーゲン結合型成長因子を用いた運動器再生2019

    • Author(s)
      内田健太郎、松下 治、井上 玄、美間健彦、高相晶士
    • Organizer
      第51回 日本結合組織学会学術大会
    • Data Source
      KAKENHI-PROJECT-17K10982
  • [Presentation] コラーゲン結合型塩基性線維芽細胞成長因子とコラーゲン基剤を用いた複合剤の歯周組織再生への応用2018

    • Author(s)
      中村 心、伊東 孝、松下 治、岡本 憲太郎、美間 健彦、内田 健太郎、高柴 正悟、他7名
    • Organizer
      第61回秋季日本歯周病学会学術大会
    • Data Source
      KAKENHI-PROJECT-18K07111
  • [Presentation] Structural analysis of a matrix anchor in bacterial collagenase to develop a therapeutic to induce osteogenesis.2017

    • Author(s)
      Osamu Matsushita, Kentaro Uchida, Hiroyuki Sekiguchi, Takehiko Mima, Kazuyoshi Goto, Yumiko Yamamoto, Kenji Yokota, Masashi Takaso, Ryan Bauer, Joshua Sakon
    • Organizer
      第90回日本細菌学会総会
    • Place of Presentation
      仙台国際センター(宮城県仙台市)
    • Year and Date
      2017-03-19
    • Data Source
      KAKENHI-PROJECT-26460527
  • [Presentation] 新規コラーゲン結合型線維芽細胞増殖因子による骨形成促進法の開発2016

    • Author(s)
      関口裕之、内田健太郎、井上玄、相川淳、斉藤亘、宮城正行、松下治、藤巻寿子、高野昇太郎、名倉直重、高相晶士.
    • Organizer
      第31回日本整形外科学会基礎学術集会
    • Place of Presentation
      福岡国際会議場(福岡県福岡市)
    • Year and Date
      2016-10-13
    • Data Source
      KAKENHI-PROJECT-26293341
  • [Presentation] 合成コラーゲン様基剤とコラーゲン結合型線維芽細胞増殖因子を用いた複合剤による骨形成促進法の開発2016

    • Author(s)
      濱本奈々,内田健太郎,関口裕之,美間健彦,後藤和義,山本由弥子,横田健治,高相晶士,松下 治
    • Organizer
      第89回日本細菌学会総会
    • Place of Presentation
      大阪府大阪市
    • Year and Date
      2016-03-23
    • Data Source
      KAKENHI-PROJECT-26460527
  • [Presentation] 細菌分子によるマトリックスアンカーリング機構を応用した骨形成促進法の開発2015

    • Author(s)
      内田健太郎、松下 治、齋藤 亘、井上 玄、高相晶士
    • Organizer
      第18回北里微生物アカデミー研究集会
    • Place of Presentation
      北里大学(神奈川県相模原市)
    • Year and Date
      2015-08-06
    • Data Source
      KAKENHI-PROJECT-26293341
  • [Presentation] 細菌毒素の機能性ドメインを用いた新規再生医療用複合材料2015

    • Author(s)
      松下 治,内田健太郎,西 望,小出隆規,Joshua Sakon
    • Organizer
      第15回日本蛋白質科学会年会
    • Place of Presentation
      徳島県徳島市
    • Year and Date
      2015-06-24
    • Invited
    • Data Source
      KAKENHI-PROJECT-26460527
  • [Presentation] Bone powder とコラーゲン結合型線維芽細胞増殖因子による骨折後の骨形成促進効果の検討.2014

    • Author(s)
      斎藤 亘、内田健太郎、井上 玄、松下 治、大貫裕子、藤巻寿子、関口裕之、相川 淳、高平尚伸、高相晶士.
    • Organizer
      第33回日本運動器移植・再生医学研究会
    • Place of Presentation
      第一ホテル両国(東京都墨田区)
    • Year and Date
      2014-09-27
    • Data Source
      KAKENHI-PROJECT-26293341
  • [Presentation] Drug delivery based on clostridial collagenase showed therapeutic effects in orthopedic surgery2014

    • Author(s)
      松下治、美間健彦、山本由弥子、鈴木智典、横田憲二
    • Organizer
      第87回日本細菌学会
    • Place of Presentation
      東京都江戸川区船堀
    • Data Source
      KAKENHI-PROJECT-23590516
  • [Presentation] Drug delivery based on clostridial collagenase showed therapeutic effects in orthopedic surgery2014

    • Author(s)
      松下 治、美間健彦、山本由弥子、鈴木智典、横田憲治
    • Organizer
      第87回日本細菌学会総会
    • Place of Presentation
      東京都江戸川区船堀
    • Data Source
      KAKENHI-PROJECT-23590516
  • [Presentation] Structural comparison od collagen- binding domains derived from Clostridium histolyticum collagenases2013

    • Author(s)
      松下治、美間健彦、山本由弥子、鈴木智典、横田憲二
    • Organizer
      第86回日本細菌学会
    • Place of Presentation
      千葉県千葉市
    • Data Source
      KAKENHI-PROJECT-23590516
  • [Presentation] ガス壊疽菌群コラゲナーゼの基質認識機構の解明と臨床応用2012

    • Author(s)
      松下治、美間健彦、鈴木智典、山本由弥子、横田憲治、小出隆規、安達栄治郎、玉井栄治、宮田茂、南純三朗、岡部昭延
    • Organizer
      第65回日本細菌学会中国・四国支部総会
    • Place of Presentation
      徳島県徳島市
    • Data Source
      KAKENHI-PROJECT-23590516
  • [Presentation] コラーゲン結合ドメインを持つヒトEGFが三次元培養皮膚モデルの表皮重層化に及ぼす影響2012

    • Author(s)
      笠原薫、松下治、安達栄治郎、西山敏夫 他1名
    • Organizer
      第85回日本生化学会大会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-22300167
  • [Presentation] 細菌性コラゲナーゼの基質認識と臨床応用2012

    • Author(s)
      松下治
    • Organizer
      第三回愛媛微生物学ネットワーク フォーラム
    • Place of Presentation
      愛媛県松山市
    • Invited
    • Data Source
      KAKENHI-PROJECT-23590516
  • [Presentation] Bacterial collagen-binding domains - Molecular basics and clinical applications2012

    • Author(s)
      Osamu Matsushita, Takehiko Mima, Eijiro Adachi, Joshua Sakon, Nozomu Nishi, Takenori Miyashita, Nozomu Mori, Joe Inou1, Masakazu Hattori, Minekatsu Akimoto, Akira Takeda, Eiju Uchinuma
    • Organizer
      第85回 日本細菌学会総会
    • Place of Presentation
      長崎県長崎市
    • Data Source
      KAKENHI-PROJECT-23590516
  • [Presentation] 細菌性コラゲナーゼの基質認識と臨床応用2012

    • Author(s)
      松下治
    • Organizer
      第三回愛媛微生物学ネットワークフォーラム
    • Place of Presentation
      愛媛県松山市
    • Year and Date
      2012-11-10
    • Invited
    • Data Source
      KAKENHI-PROJECT-23590516
  • [Presentation] Bacterial collagen-binding domains - Molecular basics and clinical applications2012

    • Author(s)
      Osamu Matsushita, Takehiko Mima, Eijiro Adachi, Joshua Sakon, Nozomu Nishi, Takenori Miyashita, NozomuMori, JoeInoue, Masakazu Hattori, Minekatsu Akimoto, Akira Takeda, Eiju Uchinuma
    • Organizer
      第85回日本細菌学会総会
    • Place of Presentation
      長崎県長崎市
    • Year and Date
      2012-03-27
    • Data Source
      KAKENHI-PROJECT-23590516
  • [Presentation] Bacterial collagen-binding domains-Molecular basis and clinical applications2012

    • Author(s)
      松下治, 他3名
    • Organizer
      第85回日本細菌学会総会
    • Place of Presentation
      長崎新聞文化ホール(長崎県)
    • Year and Date
      2012-03-27
    • Data Source
      KAKENHI-PROJECT-22300167
  • [Presentation] Medial application of clostridial toxins ; 2) Collagenases2011

    • Author(s)
      松下治, 他10名
    • Organizer
      第84回日本細菌学会総会
    • Place of Presentation
      札幌コンベンションセンター(北海道)
    • Data Source
      KAKENHI-PROJECT-22300167
  • [Presentation] ガス壊疽菌群コラゲナーゼの基質結合ドメインと再生医療への応用2010

    • Author(s)
      松下治、西望、小杉日登美、小出隆規、安達栄治郎、坂本恵子、服部雅一
    • Organizer
      第57回トキシンシンポジウム
    • Place of Presentation
      長浜ロイヤルホテル(滋賀県)
    • Year and Date
      2010-07-16
    • Data Source
      KAKENHI-PROJECT-20590452
  • [Presentation] ガス壊疽菌群コラゲナーゼの基質結合ドメインと再生医療への応用2010

    • Author(s)
      松下治、西望、小杉日登美、小出隆規、安達栄治郎、坂本恵子、服部雅一
    • Organizer
      第57回トキシンシンポジウム
    • Place of Presentation
      滋賀県長浜市
    • Year and Date
      2010-07-16
    • Data Source
      KAKENHI-PROJECT-20590452
  • [Presentation] Collagen anchoring : From bacterial toxin to drug2010

    • Author(s)
      Osamu Matsushita
    • Organizer
      11th Joint Symposium Robert Koch Institute and The Kitasato Institute Kitasato University
    • Place of Presentation
      北里大学薬学部コンベンションホール(東京都)
    • Year and Date
      2010-10-26
    • Data Source
      KAKENHI-PROJECT-20590452
  • [Presentation] コラーゲン結合ドメインの構造解析と薬物送達システムへの応用2010

    • Author(s)
      松下治、宮田茂
    • Organizer
      第83回日本細菌学会
    • Place of Presentation
      神奈川県横浜市
    • Year and Date
      2010-03-27
    • Data Source
      KAKENHI-PROJECT-20590452
  • [Presentation] From bacterial toxin to drug.2010

    • Author(s)
      Matsushita O., Collagen anchoring
    • Organizer
      11th Joint Symposium Robert Koch Institute and The Kitasato Institute Kitasato University
    • Place of Presentation
      東京都港区
    • Year and Date
      2010-10-26
    • Data Source
      KAKENHI-PROJECT-20590452
  • [Presentation] Substrate recognition of collagen-binding domains derived from bacterial collagenases2009

    • Author(s)
      Matsushita O, Nishi N, Koide T, Philominathan STL, Sakon J Gensure RC, Iwashiro H, Adachi E
    • Organizer
      8th Pan-pacific connective tissue societies symposium, 41st Annual meeting of the Japanese society of connective tissue research, 56th Annual meeting of the Japan matrix club
    • Place of Presentation
      神奈川県逗子市
    • Year and Date
      2009-06-04
    • Data Source
      KAKENHI-PROJECT-20590452
  • [Presentation] ガス壊疽菌群コラゲナーゼの基質結合様式と積層型人工組織作製への応用2009

    • Author(s)
      松下治
    • Organizer
      第56回トキキンシンポジウム
    • Place of Presentation
      岐阜県岐阜市
    • Year and Date
      2009-08-27
    • Data Source
      KAKENHI-PROJECT-20590452
  • [Presentation] ガス壊疽菌群コラゲナーゼの基質認識機構と再生医学への応用2009

    • Author(s)
      松下治、小出隆規、安達栄治郎
    • Organizer
      第82回日本細菌学会総会
    • Place of Presentation
      愛知県名古屋市
    • Year and Date
      2009-03-12
    • Data Source
      KAKENHI-PROJECT-20590452
  • [Presentation] Substrate recognition of collagen-binding domains derived from bacterial collagenases.2009

    • Author(s)
      Matsushita O., Nishi N., Koide T., Philominathan S.T.L., Sakon J., Gensure R.C., Iwashiro H., Adachi E.
    • Organizer
      8th Pan-pacific connective tissue societies symposium, 41st Annual meeting of the Japanese society of connective tissue research, 56th Annual meeting of the Japan matrix club
    • Place of Presentation
      神奈川県逗子市
    • Year and Date
      2009-06-04
    • Data Source
      KAKENHI-PROJECT-20590452
  • [Presentation] ガス壊疽菌群コラゲナーゼの基質認識機構と骨粗鬆症治療への応用2008

    • Author(s)
      松下 治
    • Organizer
      第81回日本細菌学会総会
    • Place of Presentation
      京都府京都市
    • Year and Date
      2008-03-25
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590429
  • [Presentation] Collagen binding mechanism of a novel osteoporosis drug.2008

    • Author(s)
      PST Leena, O Matsushita, R Gensure, J Sakon
    • Organizer
      51st Annunal Meeting of Biophysical Society
    • Place of Presentation
      Baltjmore,Maryland,USA
    • Year and Date
      2008-03-05
    • Data Source
      KAKENHI-PROJECT-18590429
  • [Presentation] Collagen binding mechanism of a novel osteoporosis drug2008

    • Author(s)
      PST Leena, O Matsushita, R Ge nsure, J Sakon
    • Organizer
      51st Annunal Meeting of Biophysical Society
    • Place of Presentation
      Baltimore,Maryland,USA
    • Year and Date
      2008-03-05
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590429
  • [Presentation] Vector construction for production and purification of clostridial collagenases. (in Japanese)2008

    • Author(s)
      Y, Tanaka, E, Tamai, S, Miyata, A, Okabe, H, Hohchi, O, Matsushita
    • Organizer
      81st Annual Meeting of Japanese Society for Bacteriology
    • Place of Presentation
      Kyoto, Kyoto
    • Year and Date
      2008-03-24
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590429
  • [Presentation] Substrate recognition mechanism of clostridial collagenases and its application to the treatment of osteoporosis. (in Japanese)2008

    • Author(s)
      O, Matsushita
    • Organizer
      81st Annual Meeting of Japanese Society for Bacteriology
    • Place of Presentation
      Kyoto, Kyoto
    • Year and Date
      2008-03-24
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590429
  • [Presentation] ガス壊疽菌群コラゲナーゼのセグメント2の構造解析2008

    • Author(s)
      松下治
    • Organizer
      第91回日本細菌学会関東支部総会
    • Place of Presentation
      千葉県長生郡長塚町
    • Year and Date
      2008-10-23
    • Data Source
      KAKENHI-PROJECT-20590452
  • [Presentation] Collagen binding mechanism of a novel osteoporosis drug2008

    • Author(s)
      PST, Leena, O, Matsushita, R, Gensure, J, Sakon
    • Organizer
      51st Annunal Meeting of Biophysical Society
    • Place of Presentation
      Baltimore, Maryland, USA
    • Year and Date
      2008-03-05
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590429
  • [Presentation] A novel drug delivery system based on the substrate recognition mechanism of clostridial collagenases. (in Japanese)2008

    • Author(s)
      O, Matsushita
    • Organizer
      90th Annual Meeting of Kanto branch, Japanese Society for Bacteriology
    • Place of Presentation
      Shinjuku, Tokyo
    • Year and Date
      2008-10-12
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590429
  • [Presentation] クロストリジウム菌コラゲナーゼの産生と精製用のベクターの構築2008

    • Author(s)
      田中 裕章、玉井 栄治、宮田 茂、岡部 昭延、芳地 一、松下 治
    • Organizer
      第81回日本細菌学会総会
    • Place of Presentation
      京都府京都市
    • Year and Date
      2008-03-24
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590429
  • [Presentation] Weekly administration of a novel parathyroid hormone-Collagen-binding domain fusion protein increases bone mineral density by more than 15 percent in normal mouse.2007

    • Author(s)
      T Ponnapakkam, O Matsushita, J Sakon, RC Censure
    • Organizer
      The American Society for Bone and Mineral Research
    • Place of Presentation
      Honolulu,Hawaii,USA
    • Year and Date
      2007-09-19
    • Data Source
      KAKENHI-PROJECT-18590429
  • [Presentation] Vibzlo alginolyticusのコラーゲン分解レギュロンの発現調節について2007

    • Author(s)
      松下 治、宮田 茂、玉井 栄治、岡部 昭延
    • Organizer
      第80回日本細菌学会総会
    • Place of Presentation
      大阪府大阪市
    • Year and Date
      2007-03-26
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590429
  • [Presentation] Expression regulation of collagenolytic regulon in Vibrio altinolyticus. (in Japanese)2007

    • Author(s)
      O, Matsushita, S, Miyata, E, Tamai, A, Okabe
    • Organizer
      80th Annual Meeting of Japanese Society for Bacteriology
    • Place of Presentation
      Osaka, Osaka
    • Year and Date
      2007-03-26
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590429
  • [Presentation] Weekly administration of a novel parathyroid hormone - Collagen-binding domain fusion protein increases bone mineral density by more than 15 percent in normal mouse2007

    • Author(s)
      T Ponnapakkam, O Matsushita, J Sakon, RC Gensure
    • Organizer
      The American Society for Bone and Mineral Research
    • Place of Presentation
      Honolulu,Hawaii,USA
    • Year and Date
      2007-09-19
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590429
  • [Presentation] ガス壊疽菌群コラゲナーゼの基質認識機構と薬物送達システムへの応用2007

    • Author(s)
      松下 治
    • Organizer
      第90回日本細菌学会関東支部総会
    • Place of Presentation
      東京都新宿区
    • Year and Date
      2007-10-12
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590429
  • [Presentation] Weekly administration of a novel parathyroid hormone-Collagen-binding domain fusion protein increases bone mineral density by more than 15 percent in normal mouse2007

    • Author(s)
      T, Ponnapakkam, O, Matsushita, J, Sakon, RC, Gensure
    • Organizer
      The American Society for Bone and Mineral Research
    • Place of Presentation
      Honolulu, Hawaii, USA
    • Year and Date
      2007-09-17
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590429
  • [Presentation] Collagen binding characteristics of collagen-binding domain from Clostri dium histolyticum class I collagenase2007

    • Author(s)
      J Sakon, PST Leena, O Matsushita
    • Organizer
      The American Society for Bone and Mineral Research
    • Place of Presentation
      Honolulu,Hawaii,USA
    • Year and Date
      2007-09-17
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590429
  • [Presentation] Collagen binding charactehstics of collagen-binding dolmain from Clostridium histolvticum class I collagenase.2007

    • Author(s)
      J Sakon, PST Leena, O Matsushita
    • Organizer
      The American Society for Bone and Mineral Research
    • Place of Presentation
      Honolulu,Hawau,USA
    • Year and Date
      2007-09-17
    • Data Source
      KAKENHI-PROJECT-18590429
  • [Presentation] Collagen binding characteristics of collagen-binding domain from Clostridium histolyticum class I collagenase2007

    • Author(s)
      J, Sakon, PST, Leena, O, Matsushita
    • Organizer
      The American Society for Bone and Mineral Research
    • Place of Presentation
      Honolulu, Hawaii, USA
    • Year and Date
      2007-09-17
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590429
  • [Presentation] Vibrio alginolyticusコラゲナーゼの性状と発現調節2006

    • Author(s)
      松下 治、谷口 有紀、宮田 茂、玉井 栄治、田中 裕章、岡部 昭延
    • Organizer
      第59回日本細菌学会中国、四国支部総会
    • Place of Presentation
      山口県宇部市
    • Year and Date
      2006-10-18
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590429
  • [Presentation] Characterization of Vibrio alginolyticus collagenase and its expression regulation. (in Japanese)2006

    • Author(s)
      O, Matsushita, Y, Taniguchi, S, Miyata, E, Tamai, Y, Tanaka, A, Okabe
    • Organizer
      59th Annual Meeting of Chugoku-Shikoku branch, Japanese Society for Bacteriology
    • Place of Presentation
      Ube, Yamaguchi
    • Year and Date
      2006-10-18
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590429
  • [Presentation] Acceleration of periosteal bone formation by human basic fibroblast growth factor containing a collagen-binding domain from Clostridium histolyticum collagenase

    • Author(s)
      Uchida K, Matsushita O, Naruse K, Inoue G, Takaso M.
    • Organizer
      World Congress on Controversies, Debates & Consensus in Bone, Muscle & Joint Diseases
    • Place of Presentation
      Brussels
    • Data Source
      KAKENHI-PROJECT-25670659
  • [Presentation] コラーゲン結合性線維芽細胞増殖因子(bFGF-CBD)とコラーゲンシートの併用による同種骨移植後の骨癒合促進

    • Author(s)
      上野正喜、内田健太郎、斉藤 亘、余頃瑞希、井上玄、松下治、高平尚伸、高相晶士.
    • Organizer
      第28回日本整形外科学会基礎学術集会
    • Place of Presentation
      幕張
    • Data Source
      KAKENHI-PROJECT-25670659
  • [Presentation] 脊椎手術におけるコラーゲン結合ドメインを融合した塩基性線維芽細胞増殖因子の骨形成に与える影響

    • Author(s)
      井上玄、内田健太郎、上野正喜、斉藤亘、中澤俊之、井村貴之、松下治、高平尚伸、高相晶士.
    • Organizer
      第28回日本整形外科学会基礎学術集会
    • Place of Presentation
      幕張
    • Data Source
      KAKENHI-PROJECT-25670659
  • [Presentation] Injectable コラーゲンパウダーとコラーゲン結合型線維芽細胞増殖因子による骨折後の骨形成促進効果の検討

    • Author(s)
      斉藤 亘、内田健太郎、上野正喜、井上 玄、大貫裕子、松下治、高相晶士.
    • Organizer
      第28回日本整形外科学会基礎学術集会
    • Place of Presentation
      幕張
    • Data Source
      KAKENHI-PROJECT-25670659
  • [Presentation] 線維芽細胞増殖因子アンカーリング間葉系細胞積層シートの骨形成能の検討

    • Author(s)
      内田健太郎、堀川恭佑、井上玄、松下 治、斎藤亘、成瀬康治、藤巻寿子、占部憲、高相晶士.
    • Organizer
      第29回日本整形外科学会基礎学術集会
    • Place of Presentation
      城山観光ホテル(鹿児島県鹿児島市)
    • Year and Date
      2014-10-09 – 2014-10-10
    • Data Source
      KAKENHI-PROJECT-25670659
  • [Presentation] ガス壊疽菌コラゲナーゼの基質結合ドメインと再生医療への応用(第2報)

    • Author(s)
      松下 治、美間健彦、山本由弥子、後藤和義、西 望、小出隆規、内田健太郎、高相晶士、他5名
    • Organizer
      第61回トキシンシンポジウム
    • Place of Presentation
      徳島県鳴門市
    • Year and Date
      2014-09-03 – 2014-09-05
    • Data Source
      KAKENHI-PROJECT-26460527
  • [Presentation] Acceleration of bone formation during fracture healing by injectable collagen powder and human basic fibroblast growth factor containing a collagen-binding domain from Clostridium histolyticum collagenase

    • Author(s)
      Saito W, Uchida K, Ueno M, Matsushita O, Inoue G, Nishi N, Ogura T, Hattori S, Fujimaki H, Tanaka K, Takaso M.
    • Organizer
      APASTB/JSTT Combined Scientific Meeting 2014
    • Place of Presentation
      長良川国際会議場(岐阜県岐阜市)
    • Year and Date
      2014-08-27 – 2014-08-29
    • Data Source
      KAKENHI-PROJECT-26293341
  • [Presentation] ボツリヌス毒素を利用した神経障害性疼痛治療

    • Author(s)
      松香芳三,丸濱功太郎,山本由弥子,小熊惠二,松下治
    • Organizer
      第88回日本細菌学会総会
    • Place of Presentation
      岐阜
    • Year and Date
      2015-03-26 – 2015-03-28
    • Data Source
      KAKENHI-PROJECT-26350499
  • [Presentation] 三叉神経におけるA型ボツリヌス神経毒素の局在と軸索輸送

    • Author(s)
      山本由弥子,丸濱功太郎,松香芳三,美間健彦,後藤和義,横田憲治,松下治,小熊惠二
    • Organizer
      第67回日本細菌学会中国・四国支部総会
    • Place of Presentation
      徳島
    • Year and Date
      2014-10-04 – 2014-10-05
    • Data Source
      KAKENHI-PROJECT-26350499
  • [Presentation] Growth factor delivery based on substrate-binding domains derived from a clostridial collagenase.

    • Author(s)
      松下 治、美間健彦、後藤和義、山本由弥子、横田憲治、内田健太郎
    • Organizer
      第88回日本細菌学会総会
    • Place of Presentation
      岐阜県岐阜市
    • Year and Date
      2015-03-26 – 2015-03-28
    • Data Source
      KAKENHI-PROJECT-26460527
  • 1.  OKABE Akinobu (20093677)
    # of Collaborated Projects: 11 results
    # of Collaborated Products: 1 results
  • 2.  UCHIDA Kentaro (50547578)
    # of Collaborated Projects: 10 results
    # of Collaborated Products: 30 results
  • 3.  MIYATA Shigeru (90314913)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 11 results
  • 4.  KATAYAMA Seiichi (70169473)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 0 results
  • 5.  MIMA Takehiko (80596437)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 20 results
  • 6.  MIMAMI Junzaburo (40157566)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 7.  INOUE Gen (80594209)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 15 results
  • 8.  TAMAI Eiji (40333512)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 3 results
  • 9.  TOKUDA Masaaki (10163974)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 10.  MABUCHI Yo (50424172)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 11.  KOBAYASHI Ryoji (00020917)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 12.  TAKASO Masashi (90439117)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 13 results
  • 13.  KOIDE Takaki (70322253)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 9 results
  • 14.  宮城 正行 (90627556)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 1 results
  • 15.  URABE Ken (90284489)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 16.  ADACHI Eijiro (30110430)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 4 results
  • 17.  TOKUMITSU hiroshi (20237077)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 18.  大鳥 精司 (40361430)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 19.  NARUSE Kouji (60276087)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  ITOMAN Moritoshi (70104528)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  AKAIKE Toshihiro (30101207)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  TAGAWA Youichi (70262079)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  NISHIYAMA Toshio (60372455)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 24.  HATTORI Masakazu (40211479)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  INOUE Jo (00433714)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 26.  MORI Nozomu (90124883)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 27.  MIYASHITA Takenori (60363214)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 28.  Matsumoto Hiroshi (20423329)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  KANEMASA Yasuhiro (80033059)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  FUJII Mari (40212485)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  KOTANI Nobuyuki (80231314)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  KUNITOMI Taiji (10033292)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 33.  HIRAI Yoshikazu (00127581)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 34.  SUGIMOTO Katsuyoshi (80322270)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 35.  TAKEUCHI Yoshiki (20116619)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 36.  NISHI Nozomu (10145047)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 37.  NARIYA Hirofumi (30452668)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 38.  YAMAMOTO YUMIKO (20403496)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 39.  Onuma Kenji (80348557)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 40.  Kasahara Shingo (90233692)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 41.  Okada Hiroyuki (60263563)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 42.  Takashiba Shogo (50226768)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 43.  杉山 成史 (80379776)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 44.  山口 文徳 (40271085)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 45.  松香 芳三 (90243477)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 46.  丸濱 功太郎 (60712792)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 47.  齋藤 亘 (60439099)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 48.  王 英正 (50372579)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 49.  後藤 和義 (20626593)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 50.  横田 憲治 (00243460)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 51.  田中 健大 (70549857)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 52.  岡上 昇太郎 (20839716)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 53.  伊東 孝 (30636238)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 54.  平山 晴子 (40635257)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 55.  山本 直史 (50432662)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 56.  廣澤 直也 (10882748)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 57.  佐藤 雅 (40611843)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 58.  平井 健太 (50814224)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 59.  OGUMA Keiji
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 60.  SAKON Joshua
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results

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