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Kobayashi Eiji  小林 英司

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… Alternative Names

KOBAYASHI Eiji  小林 英司

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Researcher Number 00245044
Other IDs
Affiliation (Current) 2025: 東京慈恵会医科大学, 医学部, 教授
2025: 自治医科大学, 医学部, 客員教授
Affiliation (based on the past Project Information) *help 2022: 慶應義塾大学, 医学部(信濃町), 特任教授
2022: 東京慈恵会医科大学, 医学部, 教授
2021: 慶應義塾大学, 医学部(信濃町), 客員教授
2016 – 2020: 慶應義塾大学, 医学部(信濃町), 特任教授
2012 – 2017: 自治医科大学, 医学部, 研究員 … More
2016: 自治医科大学, 医学部, 非常勤講師
2016: 慶應義塾大学, 医学部 ブリヂストン臓器再生医学寄附講座, 特任教授
2015: 慶應義塾大学, 医学部, 教授
2013 – 2015: 自治医科大学, 医学部, 客員教授
2014: 自治医科大学, 先端医療技術開発センター, 特任教授
2009 – 2011: 自治医科大学, 医学部, 客員教授
2001 – 2011: 自治医科大学, 医学部, 教授
2010: 東京医科歯科大学, 自治医科大学医学部, 教授
1995 – 2000: 自治医科大学, 医学部, 助教授
1993 – 1994: 自治医科大学, 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
General surgery / Gastroenterology / Digestive surgery / Laboratory animal science
Except Principal Investigator
Hematology / General surgery / General surgery / Basic Section 55010:General surgery and pediatric surgery-related / Digestive surgery / Urology … More / Thoracic surgery / Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields / Biomedical engineering/Biomaterial science and engineering / Respiratory surgery / Dermatology / Circulatory organs internal medicine / 応用薬理学・医療系薬学 / Applied pharmacology / Orthopaedic surgery Less
Keywords
Principal Investigator
遺伝子銃 / KRP-203 / FTY720 / Viral hepatitis / ウイルス性肝炎 / gene therapy / 遺伝子治療 / Lymphocyte homing / Chronic hepatitis / リンパ球ホーミング … More / ウイスル性肝炎 / 慢性肝炎 / Gene gun / Hydrodynamic DNA injection / KF506 / Non-specific immunosuppressant / DNA vaccine / Liver transplantation / ラット / B型肝炎 / 非特異的免没抑制剤 / ハイドロダイナミクス法 / FK506 / 非特異的免疫抑制剤 / DNAワクチン / 肝移植 / solid tumor therapy / local therapy / Gene Gun / 固形癌治療 / 局所治療 / cancer therapy / metabolic disorder / gene gun / 肝酵素欠損病 / 癌治療 / 代謝性疾患 / 再生医学 / 臓器移植 / 再生医療 / ミニブタ / 病態モデル … More
Except Principal Investigator
免疫寛容 / 小腸移植 / インヒビター / 血友病A / 異種移植 / GVHD / ラット / 第VIII因子欠損マウス / 移植 / in vivo bioreactor / ブタ / 心筋細胞 / BRM / OK-432 / サイトカイン / 拒絶反応 / 短腸症候群 / 移植免疫 / ワクチン / 腎移植 / 細胞療法 / 遺伝子治療 / 細胞移植 / 間葉系幹細胞 / 再生医療 / 細胞治療 / ARDS / 肺障害 / 白血球 / 免疫抑制剤 / 吸収機能 / 細胞競合 / 潰瘍性大腸炎関連腫瘍 / 臓器再生 / 再生機構 / 小腸疾患 / 体性幹細胞 / オルガノイド / 炎症性腸疾患 / 潰瘍性大腸炎 / 上皮置換 / 組織修復 / 幹細胞 / ヒトiTS細胞 / iTS細胞 / 膵島 / 脾内移植 / ヒトiTP細胞 / 臓器作成 / 超急性拒絶反応 / 肝再生 / 肝移植 / 血管網付与 / 細胞シート / ヒト組織モデル / 組織モデル / マトリックス / 気管 / 肺 / 移植・再生医療 / 再細胞化 / 再生 / 組織工学 / 細胞外マトリックス / 気管移植 / 肺移植 / 組織骨格 / 臓器移植 / 脱細胞化 / 気管再生 / 肺再生 / 小児移植 / Interferon-lambda / Adontive immune cell transfer / Histone deacetylase inhibitor / vaccine / Tumor immunology / Melanoma / interferon-λ / ヒストン脱アセチル化阻害剤 / インターフェロン-λ / 養子リンパ球移入 / ヒストン脱アセチル阻害剤 / 腫瘍免疫 / メラノーマ / high resolution image system / regulatory T cells / thymus / immune tolerance / inhibitor / factor VIII / hemophilia A / 樹状細胞 / 抗第VIII因子インヒビター / SIVベクター / 胸腺 / 制御性T細胞 / 胸腺組織 / Phoshpodiesterase / Nitric oxide / Acute lung injury / Polymorphonuclear leukocyte / Green flurescent protein / knockout mice / Neonate / Immune tolerance / Hemophilia A / Factor VIII / ウイルスベクター / 新生児 / Cardiomyocyte / Inflammation / Oxidative stress / Ischemic heart disease / Atherosclerosis / Cytokine / 炎症反応 / 酸化ストレス / 虚血性心疾患 / 動脈硬化 / small intestine / rat / intraportal injection / Immunosuppression / transplantation / 門脈内注入 / 小腸 / 門脈内投与 / 免疫抑制 / dihydropyrimidine dehydrogenase / reference range / pharmacokinetics / urinary dihydrouracil / urinary uracil / 5-fluorouracil / ジヒドロピリミジンデヒドロゲナーゼ / 適正使用 / 薬物動態 / 尿中ジヒドロウラシル / 尿中ウラシル / 5-FU / Oncogenic Virus / Chemokine / Tumorcidal Effect / Neutrophilic Leucocytes / Cytokines / Milky Spots / apoptosis / cytokines / 抗腫瘍作用 / PC-C203U / 腸内最近 / 腸内細菌 / ケモカイン / 抗腫瘍性反応 / 好中球 / 乳斑 / Xeno transplantation / Acute liver failure / Auxiliary liver transplantation / 門脈-静脈シャント / 動物モデル / 急性肝不全 / 補助肝移植 / neovasculization / rejection / newborn / small bowel transplantation / 消化管運動 / 新生仔ドナー / 血管新生 / 移植片対宿主病 / 新生児ドナー / Transplantation Immunology / Gut Hormon / Digestion / Absorption / Small Bowel Transplantation / オレイン酸負荷 / リンパ管再疎通 / 胆汁酸 / 脂肪吸収 / 腸ホルモン / 消化吸収 / 高血圧 / 脂肪肝 / 小腸不全関連肝障害 / 腸管不全関連肝障害 / 腸管免疫 / ポリアミン / 短腸症 / ラットマージナル腎移植モデル / バイオイメージングシステム / ラット腎移植モデル / LacZ-Luc Transgenic rat / マージナルドナー / 腎臓移植 / 常温保存 / マージナル腎 / 移植腎繊維化 / q space imaging / 拡散テンソルMRI / 拡散MRI / BOLD MRI / 組織障害 / 移植グラフト / 臓器障害 / MRI / 胸腺上皮細胞 / 細胞移植療法 / 人工多能性幹細胞 / 血友病 / iPS細胞 / 糖尿病 / 滑膜由来幹細胞 / 関節軟骨損傷 / ミニブタ / 大型動物実験 / 低侵襲手術 / 大動物研究 / 軟骨欠損 / 滑膜幹細胞 / 幹細胞治療 / H :運動器外傷学 / PAI-1欠損マウス / キメラ肝臓 / 肝臓移植 / 移植外科学 / 植え込み型マイクロポートシステム / マイクロポート / ノックアウトマウス / マイクロポートシステム / 内皮 / 液体クロマトグラフィー / タンパク精製 / 免疫抑制因子 Less
  • Research Projects

    (34 results)
  • Research Products

    (116 results)
  • Co-Researchers

    (88 People)
  •  Differentiatio of human stem cells into pancreatic islets using porcine body as in vivo bioreactor

    • Principal Investigator
      Noguchi Hirofumi
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      University of the Ryukyus
  •  Functional analysis of small intestinal epithelial organoid-based transplant graft

    • Principal Investigator
      SUGIMOTO Shinya
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      Keio University
  •  Transplantable liver fabrication in a xenogeneic porcine as in vivo bioreactor

    • Principal Investigator
      Uemoto Shinji
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
    • Research Institution
      Shiga University of Medical Science
      Kyoto University
  •  Cell therapy for drug resistance acute rejection after intestinal transplantation

    • Principal Investigator
      MATSUURA Toshiharu
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Kyushu University
  •  Transplantation studies of tissue engineered tracha and lung regenerated from recellularized xenogeneic-decellularized scaffold

    • Principal Investigator
      TSUCHIYA Tomoshi
    • Project Period (FY)
      2015 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Respiratory surgery
    • Research Institution
      Nagasaki University
  •  Oral administration of polyamines promote adaptation in rodent model of short bowel syndrome

    • Principal Investigator
      Kasahara Naoya
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Jichi Medical University
  •  Evaluation of hypertension vaccine using pig model

    • Principal Investigator
      NAKAGAMI Hironori
    • Project Period (FY)
      2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Applied pharmacology
    • Research Institution
      Osaka University
  •  In vitro fabrication of Human heart tissue model with perfusable blood vessels

    • Principal Investigator
      Sekine Hidekazu
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biomedical engineering/Biomaterial science and engineering
    • Research Institution
      Tokyo Women's Medical University
  •  the development of revitalization methods on kidney grafting from cardiac death donors

    • Principal Investigator
      IWAI SATOMI
    • Project Period (FY)
      2013 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Kitasato University
  •  Development of novel thymus-directed strategy for central immune tolerance induction in hemophilia A

    • Principal Investigator
      MADOIWA Seiji
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Jichi Medical University
  •  establishment of a new evaluation technique by none envasive MRI

    • Principal Investigator
      TAKAHARA Shiro
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Urology
    • Research Institution
      Osaka University
  •  Development of the novel therapeutic methods for diabetes using pig's tissue-derived cells.

    • Principal Investigator
      TERATANI TAKUMI
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      General surgery
    • Research Institution
      Jichi Medical University
  •  Regulation of plasminogen activator inhibitor-1 promotes the immune response to factor VIII in murine hemophilia A.

    • Principal Investigator
      MADOIWA Seiji
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Jichi Medical University
  •  Preclinical trial of less invasive synovial stem cell therapy using a pig knee articular cartilage defect model

    • Principal Investigator
      MUNETA Takeshi
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Tokyo Medical and Dental University
  •  Liver transplantation with novel strategy using the engineered chimeric liver as alternative graft

    • Principal Investigator
      UEMOTO Shinji
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      General surgery
    • Research Institution
      Kyoto University
  •  Development of immune-tolerance induction by continuous infusion of FactorVIII using micro-injection system in murine hemophilia A

    • Principal Investigator
      MADOIWA Seiji
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Jichi Medical University
  •  Development of feasibility test system wising miniature PigPrincipal Investigator

    • Principal Investigator
      KOBAYASHI Eiji
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Laboratory animal science
    • Research Institution
      Jichi Medical University
  •  The effect of inhibition of leukocyte-endothelial interaction to the organ injuries by surgical stress.

    • Principal Investigator
      SATO Yukio
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Thoracic surgery
    • Research Institution
      Jichi Medical University
  •  Induction of factor VIII specific unresponsiveness by intrathymic factor VIII injection in murine hemophilia A

    • Principal Investigator
      MADOIWA Seiji
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Jichi Medical University
  •  The study for inhibition of the melanoma-derived factors and for efficient elicitation of the host immunity

    • Principal Investigator
      MURAKAMI Takashi
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Dermatology
    • Research Institution
      Jichi Medical University
  •  Development of the lymphocyte-homing modulator against hepatitisPrincipal Investigator

    • Principal Investigator
      KOBAYASHI Eiji, 金子 隆志
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      JICHI MEDICAL SCHOOL
  •  Induction of Immune Tolerance by Neonatal Intravenous Injection of Human Factor VIII in Murine Hemophilia A

    • Principal Investigator
      MADOIWA Seiji
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      JICFII MEDICAL SCHOOL
  •  The evaluation of organ injuries due to surgical stress using green fluorescent protein induced rat.

    • Principal Investigator
      SATO Yukio
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Thoracic surgery
    • Research Institution
      JICHI MEDICAL SCHOOL
  •  新規免疫抑制因子MAY-Iの臓器移植治療への応用とその免疫抑制機序

    • Principal Investigator
      内田 広夫
    • Project Period (FY)
      2002 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General surgery
    • Research Institution
      Dokkyo Medical University
  •  心血管疾患におけるMIFの発現とその役割

    • Principal Investigator
      TAKAHASHI Masafumi
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Shinshu University Graduate School of Medicine
      Jichi Medical University
  •  Development for DNA vaccination against viral hepatitis recurrence after the liver transplantation using gene gunPrincipal Investigator

    • Principal Investigator
      KOBAYASHI Eiji
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Digestive surgery
    • Research Institution
      Jichi Medical University
  •  Study of the mechanisms of the induction of hyporesponsiveness by intraportal infusion of donor cells by using GFP rats

    • Principal Investigator
      MATSUOKA Junji
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      OKAYAMA UNIVERSITY
  •  Cancer Gene Therapy with a Hand-Held Gene GunPrincipal Investigator

    • Principal Investigator
      KOBAYASHI Eiji
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Jichi Medical School
  •  Possible prediction to fluorouracil (5-FU) anti-cancer agent -Studies of urinary pyrimidine levels in the cancer patients and 5-FU pharmacokinetics in the patients with cancer.

    • Principal Investigator
      TOKUE Akihiko, 原田 和博
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      応用薬理学・医療系薬学
    • Research Institution
      Jichi Medical School
  •  Structure and Functions of Serosal Milky Spots

    • Principal Investigator
      KANAZAWA Kyotaro
    • Project Period (FY)
      1996 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General surgery
    • Research Institution
      JICHI MEDICAL SCHOOL
  •  Experimental studies of small bowel transplantation using newborn intestines.

    • Principal Investigator
      MIYATA Michio.MD.PhD.
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Digestive surgery
    • Research Institution
      Jichi Medical School
  •  Development of new gene therapy for metabolic disorder of the liver -in vivo gene transfection using Particle Delivery System-Principal Investigator

    • Principal Investigator
      KOBAYASHI Eiji
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Jichi Medical School
  •  Study of assisted liver transplantation for acute liver failure -Development of xeno auxiliary liver transplantation-

    • Principal Investigator
      KASAHARA Kogorou
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Jichi Medical School
  •  ABSORPTION FUNCTION AND HORMONAL CHANGES AFTER SMALL BOWEL TRANSPLANTATIN

    • Principal Investigator
      MIYATA Michio
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Jichi Medical School, Omiya Medical Center

All 2022 2021 2020 2019 2018 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 Other

All Journal Article Presentation Book Patent

  • [Book] スフィンゴシン-1-リン酸受容体アゴニストによる移植免疫調節2006

    • Author(s)
      村上 孝、小林 英司
    • Total Pages
      5
    • Publisher
      移植(日本移植学会雑誌)
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591181
  • [Book] スフィンゴシンー1-リン酸受容体アゴニストによる移植免疫調節2006

    • Author(s)
      村上 孝, 小林英司
    • Publisher
      移植(日本移植学会雑誌)
    • Data Source
      KAKENHI-PROJECT-17591181
  • [Journal Article] <i>In Vivo</i> Intestinal Research Using Organoid Transplantation2022

    • Author(s)
      Sugimoto Shinya、Kobayashi Eiji、Kanai Takanori、Sato Toshiro
    • Journal Title

      The Keio Journal of Medicine

      Volume: 71 Issue: 4 Pages: 73-81

    • DOI

      10.2302/kjm.2022-0019-IR

    • ISSN
      0022-9717, 1880-1293
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H03746, KAKENHI-PROJECT-21K19540
  • [Journal Article] An organoid-based organ-repurposing approach to treat short bowel syndrome2021

    • Author(s)
      Sugimoto S, Kobayashi E, Fujii M, Ohta Y, Arai K, Matano M, Ishikawa K, Miyamoto K, Toshimitsu K, Takahashi S, Nanki K, Hakamata Y, Kanai T, Sato T.
    • Journal Title

      Nature

      Volume: 592 Pages: 99-104

    • DOI

      10.1038/s41586-021-03247-2

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H06176, KAKENHI-PROJECT-20H03746, KAKENHI-PROJECT-20H03757, KAKENHI-PROJECT-18KK0246, KAKENHI-PROJECT-23K20316
  • [Journal Article] De novo hepatocellular carcinoma developing in the living donor liver grafts: A Japanese multicenter experience2020

    • Author(s)
      Goto R, Kosai-Fujimoto Y, Yagi S, Kobayashi T, Akamatsu N, Shimamura T, Imura S, Ogiso S, Mizuno S, Takatsuki M, Fukuhara T, Kanto T, Eguchi S, Yanaga K, Ogura Y, Fukumoto T, Shimada M, Hasegawa K, Ohdan H, Uemoto S, Soejima Y, Ikegami T, Yoshizumi T, Taketomi A, Maehara Y
    • Journal Title

      Hepatol Res

      Volume: 50 Issue: 12 Pages: 1365-1374

    • DOI

      10.1111/hepr.13565

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20H03737, KAKENHI-PROJECT-19K22656, KAKENHI-PROJECT-18H04058
  • [Journal Article] Including body composition in MELD scores improves mortality prediction among patients awaiting liver transplantation.2019

    • Author(s)
      Hamaguchi Y, Kaido T, Okumura S, Kobayashi A, Shirai H, Yao S, Yagi S, Kamo N, Uemoto S
    • Journal Title

      Clin Nutr

      Volume: in press Issue: 6 Pages: 1885-1892

    • DOI

      10.1016/j.clnu.2019.08.012

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K10511, KAKENHI-PROJECT-20K17580, KAKENHI-PROJECT-19K22656, KAKENHI-PROJECT-18H04058
  • [Journal Article] Preoperative Visceral Adiposity and Muscularity Predict Poor Outcomes after Hepatectomy for Hepatocellular Carcinoma.2019

    • Author(s)
      Hamaguchi Y, Kaido T, Okumura S, Kobayashi A, Shirai H, Yao S, Yagi S, Kamo N, Seo S, Taura K, Okajima H, Uemoto S.
    • Journal Title

      Liver Cancer

      Volume: 8 Issue: 2 Pages: 92-109

    • DOI

      10.1159/000488779

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K10511, KAKENHI-PROJECT-18H04058
  • [Journal Article] Auxiliary xenotransplantation as an in vivo bioreactor- Development of a transplantable liver graft from a tiny partial liver2019

    • Author(s)
      Masano Yuki、Yagi Shintaro、Miyachi Yosuke、Okumura Shinya、Kaido Toshimi、Haga Hironori、Kobayashi Eiji、Uemoto Shinji
    • Journal Title

      Xenotransplantation

      Volume: 26 Issue: 6

    • DOI

      10.1111/xen.12545

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K21336, KAKENHI-PROJECT-19K22656, KAKENHI-PROJECT-18H04058
  • [Journal Article] Etiologies, risk factors, and outcomes of bacterial cholangitis after living donor liver transplantation.2018

    • Author(s)
      Yao S, Yagi S, Nagao M, Uozumi R, Iida T, Iwamura S, Miyachi Y, Shirai H, Kobayashi A, Okumura S, Hamaguchi Y, Masano Y, Kaido T, Okajima H, Uemoto S.
    • Journal Title

      Eur J Clin Microbiol Infect Dis.

      Volume: 10 Issue: 10 Pages: 1973-1982

    • DOI

      10.1007/s10096-018-3333-4

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K10519, KAKENHI-PROJECT-18K08567, KAKENHI-PROJECT-18H04058
  • [Journal Article] Impact of Enteral Nutrition with an Immunomodulating Diet Enriched with Hydrolyzed Whey Peptide on Infection After Liver Transplantation2018

    • Author(s)
      Kamo Naoko、Kaido Toshimi、Hamaguchi Yuhei、Uozumi Ryuji、Okumura Shinya、Kobayashi Atsushi、Shirai Hisaya、Yagi Shintaro、Okajima Hideaki、Uemoto Shinji
    • Journal Title

      World Journal of Surgery

      Volume: 42 Issue: 11 Pages: 3715-3725

    • DOI

      10.1007/s00268-018-4680-0

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18H04058
  • [Journal Article] Bone mineral density correlates with survival after resection of extrahepatic biliary malignancies.2018

    • Author(s)
      Yao S, Kaido T, Okumura S, Iwamura S, Miyachi Y, Shirai H, Kobayashi A, Hamaguchi Y, Kamo N, Uozumi R, Yagi S, Uemoto S.
    • Journal Title

      Clin Nutr

      Volume: 37 Issue: 6 Pages: 32570-6

    • DOI

      10.1016/j.clnu.2018.12.004

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K10511, KAKENHI-PROJECT-18K08567, KAKENHI-PROJECT-18H04058
  • [Journal Article] 心停止後ラット腎臓のfunctional MRIを用いた詳細な障害の評価と腎移植後グラフト予後予測可能性2014

    • Author(s)
      貝森淳哉、岩井聡美、小林英司、畑中雅喜、津田秀年、小尾佳嗣、奥見雅由、矢澤浩治、市丸直嗣、楽木宏美、野々村祝夫、猪阪善隆、高原史郎
    • Journal Title

      Organ Biology

      Volume: 21(2) Pages: 179-181

    • NAID

      130004715801

    • Open Access
    • Data Source
      KAKENHI-PROJECT-24659714
  • [Journal Article] Impact of ex vivo administration of mesenchymal stem cells on the function of kidney grafts from cardiac death donors in rat.2013

    • Author(s)
      10. Iwai, S., Sakonju, I., Okano, S., Teratani, T., Kasahara, N., Yokote, S., Yokoo, T. and Kobayashi, E.
    • Journal Title

      Transplantation Proceedings

      Volume: 46 Pages: 1578-1584

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25462543
  • [Journal Article] Non-Invasive Magnetic Resonance Imaging in Rats for Prediction of the Fate of Grafted Kidneys from Cardiac Death Donors2013

    • Author(s)
      J Kaimori, S Iwai, M Hatanaka, T Teratani, Y Obi,H Tsuda, Y Isaka, T Yokawa, K Kuroda, N Ichimaru,MOkumi, K Yazawa, H Rakugi, N Nonomura, S Takahara, E Kobayashi
    • Journal Title

      PLOS ONE

      Volume: Volume 8 | Issue 5 |

    • NAID

      130004715801

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659714
  • [Journal Article] Use of mesenchymal stem cell-conditioned medium to activate islets in preservation solution2013

    • Author(s)
      Kasahara N, Teratani T, Doi J, Iijima Y, Maeda M, Uemoto S, Fujimoto Y, Sata N, Yasuda Y, Kobayashi E
    • Journal Title

      Cell Med

      Volume: 5 Issue: 2-3 Pages: 75-81

    • DOI

      10.3727/215517913x666477

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659623
  • [Journal Article] Use of Mesenchymal Stem Cell-conditioned Medium to Activate Islets in Preservation Solution2013

    • Author(s)
      Kasahara N, Teratani T, Doi J, Iijima Y, Maeda M, Uemoto S, Fujimoto Y, Sata N, Yasuda Y, Kobayashi E.
    • Journal Title

      Cell Medicine

      Volume: 5 Pages: 1-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659623
  • [Journal Article] Immune response against serial infusion of factor VIII antigen through an implantable venous-access device system in haemophilia A mice2012

    • Author(s)
      Madoiwa, S., et al.
    • Journal Title

      Haemophilia

      Volume: 18 Issue: 3

    • DOI

      10.1111/j.1365-2516.2011.02686.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591249, KAKENHI-PROJECT-23591426, KAKENHI-PROJECT-23591427, KAKENHI-PROJECT-24591430
  • [Journal Article] Islets from rats and pigs transgenic for photogenic proteins.2012

    • Author(s)
      Teratani T, Matsunari H, Kasahara N, Nagashima H, Kawarasaki T, Kobayashi E.
    • Journal Title

      Curr Diabetes Rev.

      Volume: 8 Pages: 382-389

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659623
  • [Journal Article] Arthroscopic, histological and MRIanalyses of cartilage repair after aminimally invasive method oftransplantation of allogeneic synovialmesenchymal stromal cells into cartilagedefects in pigs2012

    • Author(s)
      Nakamura T, Sekiya I, Muneta T, Hatsushika D, Horie M, Tsuji K, Kawarasaki T, Watanabe A, Hishikawa S, Fujimoto Y, Tanaka H, Kobayashi E
    • Journal Title

      Cytotherapy

      Volume: 14 Pages: 327-338

    • Data Source
      KAKENHI-PROJECT-21591937
  • [Journal Article] Islets From Rats and Pigs Transgenic for Photogenic Proteins2012

    • Author(s)
      Teratani T, Matsunari H, Kasahara N, Nagashima H, Kawarasaki T, Kobayashi E
    • Journal Title

      Curr Diabetes Rev

      Volume: 8(5) Issue: 5 Pages: 382-389

    • DOI

      10.2174/157339912802083504

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659623
  • [Journal Article] Immune response against serial infusion of factor VIII antigen through an implantable venous-access device system in haemophilia A mice2012

    • Author(s)
      Madoiwa, S., Kobayashi, E., Kashiwakura, Y., Sakata, A., Yasumoto, A., Ohmori, T., Mimuro, J., and Sakata, Y
    • Journal Title

      Haemophilia

      Volume: 18

    • Data Source
      KAKENHI-PROJECT-21591249
  • [Journal Article] Development of a portocaval shunt using a small intestinal segment in rats.2010

    • Author(s)
      T.Hata, S.Uemoto, E.Kobayashi, et. al.
    • Journal Title

      Microsurgery Vol30(4)

      Pages: 302-306

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249058
  • [Journal Article] Induction of factor VIII-specific unresponsiveness by intrathymic factor VIII injection in murine hemophilia A2009

    • Author(s)
      Madoiwa, S., Yamauchi, T., Kobayashi, E., Hakamata, Y., Dokai, M., Makino, N., Kashiwakura, Y., Ishiwata, A., Ohmori, T., Mimuro, J., et al
    • Journal Title

      J Thromb Haemost

      Volume: 7 Pages: 811-824

    • Data Source
      KAKENHI-PROJECT-21591249
  • [Journal Article] In vivo pharmacokinetics of ketoprofen after patch application in the Mexican hairless pig.2009

    • Author(s)
      Horie M, Sekiya I, Nakamura T, Tanaka H, Maekawa K, Nakanishi M, Muneta T, Kobayashi E.
    • Journal Title

      Biopharm Drug Dispos 30(4)

      Pages: 204-208

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591937
  • [Journal Article] Induction of factor VIII-specific unresponsiveness by intrathymic factor VIII injection in murine hemophilia A.2009

    • Author(s)
      Madoiwa S, Yamauchi T, Kobayashi E, Hakamata Y, Dokai M, Makino N, Kashiwakura Y, Ishiwata A, Ohmori T, Mimuro J, Sakata Y.
    • Journal Title

      J Thromb Haemost. 7

      Pages: 811-24

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591133
  • [Journal Article] The feasibility of an animal laboratory for teaching surgical techniques to medical students : Teaching in a non-clinical environment.2008

    • Author(s)
      Tanaka, H., Yasuda, Y., Lefor, A., Kobayashi, E.
    • Journal Title

      医学教育 39(5)

      Pages: 299-303

    • NAID

      10024792122

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18300143
  • [Journal Article] In vivo bioimaging using photogenic rats : Fate of injected bone marrow-derived mesenchymal stromal cells.2008

    • Author(s)
      Hara, M., Murakami, T., Kobayashi, E.
    • Journal Title

      Journal of autoimmunity 30(3)

      Pages: 163-171

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18300143
  • [Journal Article] In vivo bioimaging using photogenic rats : fate of injected bone marrow-derived mesenchymal stromal cells2008

    • Author(s)
      Hara M, Murakami T, Kobayashi, E
    • Journal Title

      J Autoimmun 30(3)

      Pages: 163-171

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591181
  • [Journal Article] Production of Viable Cloned Miniature Pig Embryos Using Oocytes Derived from Domestic pig Ovaries.2008

    • Author(s)
      Wakai, T., Sugimura, S., Yamanaka, K., Kawahara, M., Sasada, H., Tanaka, H., Ando, A., Kobayashi, E., Sato, E.
    • Journal Title

      Cloning Stem Cells 10(2)

      Pages: 249-262

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18300143
  • [Journal Article] In vivo bioimaging using photogenic rats: fate of injected bone marrow-derived mesenchymal stromal cells2008

    • Author(s)
      Hara M, Murakami T, Kobayashi E.
    • Journal Title

      Journal of Autoimmunity 30(3)

      Pages: 163-171

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591181
  • [Journal Article] Induction of estrus in pubertal miniature gilts.2008

    • Author(s)
      Wakai, T., Tanaka, H., Yamanaka, K., Sugimura, S., Sasada, H., Kawahara., Kobayashi, E., Sato, E.
    • Journal Title

      Animal reproducation sciens 103

      Pages: 193-198

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18300143
  • [Journal Article] In vivo bioimaging using photogenic rats: Fate of ingected bone marrow derived mesenchymal atromal cells.2008

    • Author(s)
      Hara, M., Murakami, T., Kobayashi, E.
    • Journal Title

      Journal of Autoimmunity 30(3)

      Pages: 163-171

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18300143
  • [Journal Article] Small numbers of residual tumor cells at the site of primary inoculation are critical for anti-tumor immunity following challenge at a secondary location2007

    • Author(s)
      Kakinuma T, Nadiminti H, Lonsdorf AS, Murakami T, Perez BA, Kobayashi H, Finkelstein SE, Pothiawala G, Belkaid Y, Hwang ST.
    • Journal Title

      Cancer Immunol Immunother 56(7)

      Pages: 1119-1131

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17591181
  • [Journal Article] Essential Roles of Sphingosine 1-phosphate/1P1 Receptor Axis in the Migration of Neural Stem Cells toward a Site of Spinal Cord Injury2007

    • Author(s)
      Kimura A, Ohmori T, Ohkawa R, Madoiwa S, Mimuro J, Murakami T, Kobayashi E, Hoshino Y, Yatomi Y, Sakata, Y
    • Journal Title

      Stem Cells 25(1)

      Pages: 115-124

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591181
  • [Journal Article] Essential roles of sphingosine 1-phosphate/S1P1 receptor axis in the migration of neural stem cells toward a site of spinal cord injury.2007

    • Author(s)
      Kimura, A., Ohmori, T., Ohkawa, R., Madoiwa, S., Mimuro, J., Murakami, T., Kobayashi, E., Hoshino, Y., Yatomi, Y., Sakata, Y.
    • Journal Title

      Stem Cells 25(1)

      Pages: 115-124

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18300143
  • [Journal Article] Tissue-targeted in vivo gene transfer coupled with histone deacetyl-ase inhibitor depsipeptide (FK228)enhances adenoviral infection in rat renal cancer alloaraft model systems2007

    • Author(s)
      Kobayashi M, Okada T, Murakami T, et. al.
    • Journal Title

      Urology 70(6)

      Pages: 1230-1236

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17591181
  • [Journal Article] Control of cyclosporine A-induced tumor progression using 15-Deoxyspergualin for rat cardiac transplantation2007

    • Author(s)
      Ohsawa I, Uemoto S, Kobayashi E, Murakami, T
    • Journal Title

      Transplantation 84(3)

      Pages: 424-428

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591181
  • [Journal Article] Annexin 2 and hemorrhagic disorder in vascular intimal carcinomatosis.2007

    • Author(s)
      Madoiwa S, Someya T, Hironaka M, Kobayashi H, Ohmori T, Mimuro J, Sugiyama Y, Morita T, Nishimura Y, Tarumoto T, Ozawa K, Saito K, Sakata Y.
    • Journal Title

      Thromb Res. 119

      Pages: 229-40

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591133
  • [Journal Article] Control of cyclosporine A-induced tumor progression using 15-Deox-yspergualin for rat cardiac transplantation.2007

    • Author(s)
      Ohsawa I, Uemoto S, Kobayashi E, Murakami T.
    • Journal Title

      Transplantation 84(3)

      Pages: 424-428

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17591181
  • [Journal Article] Control of cyclosporine A-induced tumor progression using 15-Deoxyspergualin for rat cardiac transplantation2007

    • Author(s)
      Ohsawa I, Uemoto S, Kobayashi E, Murakami T.
    • Journal Title

      Transplantation 84(3)

      Pages: 424-428

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17591181
  • [Journal Article] Tissue-targeted in vivo gene transfer coupled with histone deacetyl-ase inhibitor depsipeptide(FK228) enhances adenoviral infection in rat renal cancer allograft model systems2007

    • Author(s)
      Kobayashi M, Okada T, Murakami T, Ozawa O, Kobayashi E, Morit a T.
    • Journal Title

      Urology 70(6)

      Pages: 1230-1236

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17591181
  • [Journal Article] Essential roles of sphingosine 1-phosphate/S1P1 receptor axis in the migration of neural stem cells toward a site of spinal cord injury.2007

    • Author(s)
      Kimura A, Ohmori T, Ohkawa R, Madoiwa S, Mimuro J, Murakami T, Kobayashi E, Hoshino Y, Yatomi Y, Sakata Y.
    • Journal Title

      Stem Cells. 25

      Pages: 115-24

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591133
  • [Journal Article] In vivo visualization and portally repeated transplantation of bone marrow cells in rats with liver damage.2007

    • Author(s)
      Haga, J., Wakabayashi, G., Shimazu, M., Tanabe, M., Takahara, T., Azuma, T., Sato, Y., Hakamata, Y., Kobayashi, E., Kitajima, M.
    • Journal Title

      Stem Cells Dev 16(2)

      Pages: 319-327

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18300143
  • [Journal Article] Small numbers of residual tumor cells at the site of primary inoculation are critical for anti-tumor immunity following challenge at a secondary location2007

    • Author(s)
      Kakinuma T, Nadiminti H, Lonsdorf, AS, Murakami T, Perez, BA, Kobayashi H, Finkelstein, SE, Pothiawala G, Belkaid Y, Hwang, ST
    • Journal Title

      Cancer Immunol Immunother 56(7)

      Pages: 1119-1131

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591181
  • [Journal Article] Tissue-targeted in vivo gene transfer coupled with histone deacetylase inhibitor depsipeptide(FK228) enhances adenoviral infection in rat renal cancer alloeraft model systems2007

    • Author(s)
      Kobayashi M, Okada T, Murakami T, et. al.
    • Journal Title

      Urology 70(6)

      Pages: 1230-1236

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591181
  • [Journal Article] Education and research using experimental pigs in a medical school2006

    • Author(s)
      Hozumi Tanaka, Eiji Kobayashi
    • Journal Title

      Journal of Artifical Organs 9・3

      Pages: 136-143

    • NAID

      10020584707

    • Data Source
      KAKENHI-PROJECT-18300143
  • [Journal Article] 異種移植2006

    • Author(s)
      今野兼次郎、小林英司
    • Journal Title

      臨床検査 51(2)

      Pages: 213-217

    • Data Source
      KAKENHI-PROJECT-18300143
  • [Journal Article] In vivo luminescent imaging of cyclosporine A-mediated cancer progression in rats2006

    • Author(s)
      Ohsawa I, Murakami T, Uemoto S, Kobayashi, E
    • Journal Title

      Transplantation 81(11)

      Pages: 1558-1567

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591181
  • [Journal Article] Histone deacetylase inhibitor depsipeptide (FK228) suppresses the Ras-MAP kinase signaling pathway by up-regulation Rap1 and induces apoptosis in malignant melanoma2006

    • Author(s)
      Kobayashi Y, Ohtsuki M, Murakami T, et al.
    • Journal Title

      Oncogene 25(4)

      Pages: 512-524

    • Data Source
      KAKENHI-PROJECT-17591181
  • [Journal Article] In vivo luminescent imaging of cyclosporine A-mediated cancer progression inrats2006

    • Author(s)
      Ohsawa I, Murakami T, Uemoto S, Kobayashi E.
    • Journal Title

      Transplantation 81(11)

      Pages: 1558-1567

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17591181
  • [Journal Article] Antitumor activity of interferon (IFN)-lambda in murine tumor models2006

    • Author(s)
      Sato A, Ohtsuki M, Hata M, Kobayashi E, Murakami T.
    • Journal Title

      Journal of Immunology 176(12)

      Pages: 7686-9764

    • Data Source
      KAKENHI-PROJECT-17591181
  • [Journal Article] In vivo luminescent imaging of cyclosporine A-mediated cancer progression in rats2006

    • Author(s)
      Ohsawa I, Uemoto S, Kobayashi E, Murakami T
    • Journal Title

      Transplantation (In press)

    • Data Source
      KAKENHI-PROJECT-17591181
  • [Journal Article] Efficacy of mycophenolic acid combined with KRP-203, a novel immunomodulator, in a rat heart transplantation model.2006

    • Author(s)
      Suzuki C, Takahashi M, Morimoto H, Izawa A, Ise H, Fujishiro J, Murakami T, Ishiyama J, Nakada A, Nakayama J, Shimada. K, Ikeda U, Kobayashi E.
    • Journal Title

      J Heart Lung Transplant. 25

      Pages: 302-309

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590625
  • [Journal Article] Antitumor activity of interferon(IFN)-lambda in murine tumor models2006

    • Author(s)
      Sato A, Ohtsuki M, Hata M, Kobayashi E, Murakami, T
    • Journal Title

      J Immunol 176(12)

      Pages: 7686-7694

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591181
  • [Journal Article] Antitumor activity of interferon(IFN)-lambda in murine tumor models2006

    • Author(s)
      Sato A, Ohtsuki M, Hata M, Kobayashi E, Murakami T.
    • Journal Title

      Journal of Immunology 176(12)

      Pages: 7686-7694

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17591181
  • [Journal Article] 異種移植2006

    • Author(s)
      今野兼次郎, 小林英司
    • Journal Title

      臨床検査 51・2

      Pages: 213-217

    • Data Source
      KAKENHI-PROJECT-18300143
  • [Journal Article] Histone deacetylase inhibitor depsipeptide(FK228) suppresses the Ras-MAP kinase signaling pathway by up-regulation Rap1 and induces anontosis in malienant melanoma2006

    • Author(s)
      Kobayashi Y, Ohtsuki M, Murakami T, et. al.
    • Journal Title

      Oncogene 25

      Pages: 512-524

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591181
  • [Journal Article] Education and research using experimental pigs in a medical school.2006

    • Author(s)
      Tanaka, H., Kobayashi, E.
    • Journal Title

      J Artif Organs 9

      Pages: 136-143

    • NAID

      10020584707

    • Data Source
      KAKENHI-PROJECT-18300143
  • [Journal Article] Sphingosine-1-phosphate receptor agonists suppress concanavalin A-induced hepatic injury in mice.2006

    • Author(s)
      Kaneko T, Murakami T, Hakamata Y, Kawana H, Takahashi M, Yasue T, Kobayashi, E.
    • Journal Title

      Biochem.Biophys.Res.Commun (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590625
  • [Journal Article] Histone deacetylase inhibitior depsipeptide(FK228) suppresses the Ras-MAP kinase signaling pathway by up-regulation Rapt and induces apoptosis in malignant melanoma2006

    • Author(s)
      Kobayashi Y, Ohtsuki M, Murakami T, Kobayashi T, Sutheesophon K, Kitayama H, Kano Y, Kusano E, NakaQawa H, Furukawa Y.
    • Journal Title

      Oncogene 25(4)

      Pages: 512-524

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17591181
  • [Journal Article] In viro Iuminescent imaging of cyclosporine A-mediated cancer progression in rats2006

    • Author(s)
      Ohsawa I, Murakami T, Uemoto S, Kobayashi E.
    • Journal Title

      Transplantation 81(11)

      Pages: 1558-1567

    • Data Source
      KAKENHI-PROJECT-17591181
  • [Journal Article] KRP-203, a novel synthetic immunosuppressant, prolongs graft survival and attenuates chronic rejection in rat skin and heart allografts.2005

    • Author(s)
      Shimizu H, Takahashi M, Kaneko T, Murakami T, Hakamata Y, Kudou S, Kishi T, Fukuchi K, Iwanami S, Kuriyama K, Yasue T, Enosawa S, Matsumoto K, Takeyoshi I, Morishita Y, Kobayashi E.
    • Journal Title

      Circulation 111

      Pages: 222-229

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590625
  • [Journal Article] A novel immunomodulator KRP-203 combined with cyclosporine prolonged graft survival and abrogated transplant vasculopathy in rat heart allografts.2005

    • Author(s)
      Takahashi M, Shimizu H, Murakami T, Enosawa S, Suzuki C, Takeno Y, Hakamata Y, Kudou S, Izawa S, Yasue T, Kobayashi E.
    • Journal Title

      Transplant Proc. 37

      Pages: 143-145

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590625
  • [Journal Article] 免疫抑制剤の進歩2005

    • Author(s)
      小林 英司
    • Journal Title

      日本臨床 63(11)

      Pages: 1936-1943

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590625
  • [Journal Article] Recent progress in immunosuppressive drugs2005

    • Author(s)
      Kobayashi, E.
    • Journal Title

      Nippon Rinsyou. 63(11)

      Pages: 1939-1943

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590625
  • [Journal Article] Color-engineered rats and luminescent LacZ imaging : a new platform to visualize biological processes2005

    • Author(s)
      Murakami T, Kobayashi E.
    • Journal Title

      Journal of Biological Optics 10(4)

      Pages: 41204-41215

    • Data Source
      KAKENHI-PROJECT-17591181
  • [Journal Article] The feasibility of an animal laboratory for teaching surgical techniques to medical students

    • Author(s)
      Tanaka, H., Yasuda, Y., Lefor, A., Kobayashi, E.
    • Journal Title

      Teaching in a non-clinical environment. 医学教育 2008 39(5)

      Pages: 299-303

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18300143
  • [Patent] 2-アミノ-1,3-プロパンジオール誘導体を有効成分とする肝臓疾患治療剤2005

    • Inventor(s)
      小林 英司 他2名
    • Industrial Property Rights Holder
      杏林製薬株式会社
    • Industrial Property Number
      2005-295478
    • Filing Date
      2005-10-07
    • Data Source
      KAKENHI-PROJECT-16590625
  • [Patent] 2-アミノ-1,3-プロパン時オール誘導体を有効成分とする肝臓疾患治療剤2005

    • Inventor(s)
      小林英司他2名
    • Industrial Property Rights Holder
      杏林製薬株式会社
    • Industrial Property Number
      2005-295478
    • Filing Date
      2005-10-07
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590625
  • [Presentation] Development of a treatment for short bowel syndrome using small intestinal organoids2021

    • Author(s)
      Shinya Sugimoto, Eiji Kobayashi, Masayuki Fujii, Yuki Ohta, Keiko Ishikawa, Kosaku Nanki, Yoji Hakamata, Takanori Kanai, Toshiro Sato
    • Organizer
      The 16th Congress of European Crohn’s and Colitis Organisation (ECCO 2021)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03746
  • [Presentation] Proof-of-principle investigation for organoid-based hybrid intestine in a rat short bowel syndrome model2021

    • Author(s)
      Shinya Sugimoto, Eiji Kobayashi, Toshiro Sato
    • Organizer
      17th Congress of the Intestinal Rehabilitation & Transplant Association (CIRTA 2021)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03746
  • [Presentation] 異種動物を In vivo bioreactor とした肝再生戦略―ヒト過小グラフトへの展望2020

    • Author(s)
      八木真太郎、政野裕紀、宮地洋介、平田真章、白井久也、姚思遠、上本伸二、小林英司
    • Organizer
      第22回異種移植研究会
    • Data Source
      KAKENHI-PROJECT-18H04058
  • [Presentation] 短腸症候群に対するオルガノイドによる臓器リモデリング2020

    • Author(s)
      杉本真也、小林英司、袴田陽二、金井隆典、佐藤俊朗
    • Organizer
      第19回日本再生医療学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20H03746
  • [Presentation] 異種動物を In vivo bioreactor とした肝再生戦略―ヒト過小グラフトへの展望2020

    • Author(s)
      八木真太郎、政野裕紀、宮地洋介、平田真章、白井久也、姚思遠、上本伸二、小林英司
    • Organizer
      第22回日本異種移植研究会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H04058
  • [Presentation] 間葉系幹細胞分泌因子添加による小腸移植成績の改善2015

    • Author(s)
      笠原 尚哉, 寺谷 工, 土井 淳司, 藤本 康弘, 上本 伸二, 佐田 尚宏, 安田 是和, 小林 英司
    • Organizer
      第115回日本外科学会学術集会
    • Place of Presentation
      名古屋市
    • Year and Date
      2015-04-16
    • Data Source
      KAKENHI-PROJECT-26461926
  • [Presentation] 間葉系幹細胞分泌因子を用いた臓器保存の新しい試み2013

    • Author(s)
      寺谷 工、笠原尚哉、藤本康弘、上本伸二、後藤昌史、小林英司
    • Organizer
      日本臓器保存生物医学会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23659623
  • [Presentation] 膵島の賦活化因子の探索2013

    • Author(s)
      寺谷 工・笠原尚哉・土井淳司・藤本康弘・上本伸二・小林英司
    • Organizer
      第40回日本膵・膵島移植研究会
    • Place of Presentation
      高松
    • Data Source
      KAKENHI-PROJECT-23659623
  • [Presentation] 劣化膵島の蘇生法に対する革新的技術2013

    • Author(s)
      寺谷 工・藤本康弘・上本伸二・後藤昌史・小林英司
    • Organizer
      第39回日本移植学会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-23659623
  • [Presentation] 劣化膵島の再生-MSC を用いた克服に向けて2013

    • Author(s)
      寺谷 工・笠原尚哉・土井淳司・藤本康弘・上本伸二・後藤昌史・小林英司
    • Organizer
      第40回日本膵・膵島移植研究会
    • Place of Presentation
      高松
    • Data Source
      KAKENHI-PROJECT-23659623
  • [Presentation] 間葉系幹細胞分泌因子を用いた臓器保存の新しい試み2013

    • Author(s)
      寺谷 工・笠原尚哉・藤本康弘・上本伸二・後藤昌史・小林英司
    • Organizer
      第40回日本臓器保存生物医学会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23659623
  • [Presentation] MSCを用いた劣化膵島の機能回復システムの開発2012

    • Author(s)
      寺谷 工・笠原尚哉・土井淳司・藤本康弘・上本伸二・後藤昌史・小林英司
    • Organizer
      第39回日本膵・膵島移植研究会
    • Place of Presentation
      旭川
    • Data Source
      KAKENHI-PROJECT-23659623
  • [Presentation] 脂肪由来間葉系幹細胞を用いた凍結傷害膵島の賦活効果2012

    • Author(s)
      笠原尚哉・寺谷 工・土井淳司・藤本康弘・上本伸二・佐田尚宏・安田是和・小林英司
    • Organizer
      第39回日本膵・膵島移植研究会
    • Place of Presentation
      旭川
    • Data Source
      KAKENHI-PROJECT-23659623
  • [Presentation] 分離膵島の新規輸送液の開発2011

    • Author(s)
      寺谷 工・笠原尚哉・藤本康弘・上本伸二・小林英司
    • Organizer
      第38回日本臓器保存生物医学会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-23659623
  • [Presentation] Cell-transplantation therapy of the aggregation-free infusion solution with mesenchymal stem cells2011

    • Author(s)
      Takumi Teratani・Naoya Kasahara・Shinji Uemoto ・Yasuhiro Fujimoto ・Eiji Kobayashi
    • Organizer
      CTS-IXA 2011
    • Place of Presentation
      マイアミ
    • Data Source
      KAKENHI-PROJECT-23659623
  • [Presentation] Synovial Mesenchymal Stem Cells Transplantation Contributes to Cartilage Regeneration in Porcine Model2011

    • Author(s)
      Nakamura T, Sekiya I, Hatsushika D, Horie M, Tsuji K, Muneta T, Kawarasaki T, Watanabe A, Hishikawa S, Fujimoto Y, Tanaka H, Kobayashi E.
    • Organizer
      Orthopaedic ResearchSociety 2011
    • Place of Presentation
      Long Beach
    • Data Source
      KAKENHI-PROJECT-21591937
  • [Presentation] 膵島移植における新しい治療戦略2011

    • Author(s)
      寺谷 工・笠原尚哉・上本伸二・藤本康弘・小林英司
    • Organizer
      第47回日本移植学会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-23659623
  • [Presentation] 凍結保存膵島の臨床応用化を目指した新しい移植法2011

    • Author(s)
      笠原尚哉・寺谷 工・根岸幸司・岩崎純治・金澤寛之・佐田尚宏・上本伸二・藤本康弘・小林英司
    • Organizer
      第111回日本外科学会
    • Place of Presentation
      紙面開催
    • Data Source
      KAKENHI-PROJECT-23659623
  • [Presentation] Auxiliary Transplantation of the chimeric liver graft in mouse and rat combination and evaluation of the long-term survival and proliferative capacity of the transplanted graft in the recipient rat.2010

    • Author(s)
      畑俊行, 小林英司, 上本伸二, et al.
    • Organizer
      23rd International Congress of The transplantation Society.
    • Place of Presentation
      Vancouver, Canada.
    • Year and Date
      2010-08-18
    • Data Source
      KAKENHI-PROJECT-20249058
  • [Presentation] Development of regerated chimeric liver grafts in mouse and rat combination and long-term evaluation of their potential after auxiliary transplantation.2009

    • Author(s)
      畑俊行, 小林英司, 上本伸二, et al.
    • Organizer
      14^<th> Congress of the European Society for Organ Transplantation.
    • Place of Presentation
      Paris, France.
    • Year and Date
      2009-08-30
    • Data Source
      KAKENHI-PROJECT-20249058
  • [Presentation] キメラ技術を用いた再生肝臓移植の検討2009

    • Author(s)
      畑俊行、小林英司、上本伸二, 他.
    • Organizer
      第12回日本異種移植研究会
    • Place of Presentation
      鹿児島
    • Year and Date
      2009-03-09
    • Data Source
      KAKENHI-PROJECT-20249058
  • [Presentation] Long-term function of transplanted chimeric liver with autologous hepatocyte and xenobiotic scaffold in mouse and rat combination.2009

    • Author(s)
      畑俊行, 小林英司, 上本伸二, et al.
    • Organizer
      American Transplant Congress 2009.
    • Place of Presentation
      Boston, USA.
    • Year and Date
      2009-06-03
    • Data Source
      KAKENHI-PROJECT-20249058
  • [Presentation] 小腸をscaffoldに利用した臓器再生とキメラ技術の応用.2008

    • Author(s)
      畑俊行、上本伸二、小林英司, 他.
    • Organizer
      第44回日本移植学会総会
    • Place of Presentation
      大阪
    • Year and Date
      2008-09-21
    • Data Source
      KAKENHI-PROJECT-20249058
  • [Presentation] Transplantation of chimeric liver with autologous hepatocyte and xenobiotic scaffold in mouse and rat combination2008

    • Author(s)
      Toshiyuki Hata, Shinji Uemoto, Eiji Kobayashi
    • Organizer
      American Transplant Congress 2008
    • Place of Presentation
      カナダ・トロント
    • Year and Date
      2008-06-02
    • Data Source
      KAKENHI-PROJECT-20249058
  • [Presentation] 小腸をscaffoldに利用した臓器再生とキメラ技術の応用2008

    • Author(s)
      畑俊行, 岩崎純治, 上本伸二, 小林英司
    • Organizer
      第44回日本移植学会総会
    • Place of Presentation
      大阪
    • Year and Date
      2008-09-21
    • Data Source
      KAKENHI-PROJECT-20249058
  • [Presentation] Transplantation of chimeric liver with autologous hepatocyte and xenobiotic scaffold in mouse and rat combination.2008

    • Author(s)
      畑俊行, 上本伸二, 小林英司, et al.
    • Organizer
      American Transplant Congress 2008.
    • Place of Presentation
      Toronto, Canada.
    • Year and Date
      2008-06-02
    • Data Source
      KAKENHI-PROJECT-20249058
  • [Presentation] Surgical Technique in two models of auxiliary liver transplantation from mice to rats.2008

    • Author(s)
      畑俊行, 上本伸二, 小林英司, et al.
    • Organizer
      The 9th Congress of the International Society for Experimental Microsurgery.
    • Place of Presentation
      上海,中国
    • Year and Date
      2008-10-31
    • Data Source
      KAKENHI-PROJECT-20249058
  • [Presentation] 自己肝細胞によるキメラ肝臓移植2008

    • Author(s)
      畑俊行、上本伸二、小林英司, 他.
    • Organizer
      第108回日本外科学会総会
    • Place of Presentation
      大阪
    • Year and Date
      2008-05-15
    • Data Source
      KAKENHI-PROJECT-20249058
  • [Presentation] 胸腺組織を標的とした血友病Aインヒビター産生制御の基礎的検討2007

    • Author(s)
      窓岩清治,山内忠彦,小林英司,柏倉裕志,石渡 彰,大森 司,三室 淳,坂田 洋一
    • Organizer
      第69回日本血液学会・第49回日本臨床血液学会合同総会
    • Place of Presentation
      横浜
    • Year and Date
      2007-10-11
    • Data Source
      KAKENHI-PROJECT-19591133
  • [Presentation] Sensitization with the HDAC inhibitor depsipeptide promotes immune cell-mediated destruction of murine B16 melanoma2007

    • Author(s)
      T, Murakami A, Sato Y, Furukawa Y, Kano E, Kobayashi
    • Organizer
      The 94th Annual meeting of the American Society of Immunologists
    • Place of Presentation
      Miami Beach, FL
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591181
  • [Presentation] Induction of Factor VIII Specific Unresponsiveness by Intrathymic Factor VIII Injection in Murine Hemophilia A.2007

    • Author(s)
      Seiji Madoiwa, Tadahiko Yamauchi, Eiji Kobayashi, Yoji Hakamata, Yuji Kashiwakura, Akira Ishiwata, Tsukasa Ohmori, Jun Mimuro, Yoichi Sakata
    • Organizer
      XXIst Congress of the International Society on Thrombosis and Haemostasis
    • Place of Presentation
      Geneva, Switzerland
    • Year and Date
      2007-07-08
    • Data Source
      KAKENHI-PROJECT-19591133
  • [Presentation] Differential antitumor activity between IFN-lambda and IL-212007

    • Author(s)
      A, Sato M, Ohtsnki E, Kobayashi T, Murakami
    • Organizer
      The 94th Annual meeting of the American Society of Immunologists
    • Place of Presentation
      Miami Beach, FL
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591181
  • [Presentation] Sensitization with the HDAC inhibitor depsipeptide promotes immune cell-mediated destruction of murine B16 melanoma.2007

    • Author(s)
      T Murakami, A Sato, Y Furukawa, Y Kano, E Kobayashi.
    • Organizer
      The 94^<th> Annual meeting of the American Society of Immunologists.
    • Place of Presentation
      Miami Beach, FL, USA
    • Data Source
      KAKENHI-PROJECT-17591181
  • [Presentation] Sensitization with the HDAC inhibitor depsipeptide promotes immune cell-mediated destruction of murine B16 melanoma2007

    • Author(s)
      T Murakami, A Sato, Y Furukawa, Y Kano, E Kobayashi
    • Organizer
      The 94th Annual meeting of the American Society of Immunologists
    • Place of Presentation
      Miami Beach,FL
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591181
  • [Presentation] Differential antitumor activity between IFN-lambda and IL-212007

    • Author(s)
      A Sato, M Ohtsuki, E Kobayashi, T Murakami
    • Organizer
      The 94th Annual meeting of the American Society of Immunologists
    • Place of Presentation
      Miami Beach,FL
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591181
  • [Presentation] Small number of residual tumor cells at the site of primary inoculation are critical for anti-tumor immunity following challenge at a secondary location2006

    • Author(s)
      Kakinuma T, Nadiminti H, Murakami T, Perez BA, Kobayashi H, Finkelstein SE, Hwang ST.
    • Organizer
      The 67th Society for Investigative Dermatology
    • Place of Presentation
      Philadelphia,PA
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591181
  • [Presentation] ヒストン脱アセチル化阻害剤による腫瘍の転写修飾は免疫学的な腫瘍破壊を促進する2006

    • Author(s)
      村上 孝、佐藤 篤子、加納 康彦、古川 雄祐、小林 英司
    • Organizer
      第65回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591181
  • [Presentation] The antitumor activity of interferon-λ against murine tumors2006

    • Author(s)
      A Sato, M Ohtsuki, E Kobayashi, T Murakami
    • Organizer
      The 67th Society for Investigative Dermatology
    • Place of Presentation
      Philadelphia,PA
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591181
  • [Presentation] IFN-λ(IL-28/29)はNK細胞を介して抗腫瘍効果を発揮する2006

    • Author(s)
      佐藤 篤子、村上 孝、小林 英司
    • Organizer
      第65回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591181
  • [Presentation] The antitumor activity of interferon-1 against murine tumors2006

    • Author(s)
      A, Sato M, Ohtsuki E, Kobayashi T, Murakami
    • Organizer
      The 67th Society for Investigative Dermatology
    • Place of Presentation
      Philadelphia. PA
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591181
  • [Presentation] Controling Cyclosporine A-induced cancer progression using 15-deoxyspergualin in rat cardiac transplantation2006

    • Author(s)
      Ohsawa I, Murakami T, Uemoto S, Kobayashi E.
    • Organizer
      World Transplant Congress 2006
    • Place of Presentation
      Boston,MA
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591181
  • [Presentation] マウス固形癌に対するインターフェロン-Iambdaの抗腫瘍効果2005

    • Author(s)
      佐藤 篤子、村上 孝、小林 英司
    • Organizer
      第64回日本癌学会学術総会
    • Place of Presentation
      札幌
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591181
  • [Presentation] メラノーマの転写修飾による免疫学的感受性の増幅2005

    • Author(s)
      村上 孝、佐藤 篤子、加納 康彦、古川 雄祐、小林 英司
    • Organizer
      第64回日本癌学会学術総会
    • Place of Presentation
      札幌
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591181
  • [Presentation] ヒストン脱アセチル化阻害剤FK228はRap1/Krev-1を介して悪性黒色腫にアポトーシスを誘導する2005

    • Author(s)
      小林 由起子、大槻 マミ太郎、村上 孝、小林 高久, ほか
    • Organizer
      第64回日本癌学会学術総会
    • Place of Presentation
      札幌
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591181
  • [Presentation] ラット持続肝動注モデルの開発と非侵襲的生体内バイオイメージング法による新しいがん治療評価方法2005

    • Author(s)
      原 知憲、大澤 一郎、村上 孝、小林 英司、土田 明彦
    • Organizer
      第64回日本癌学会学術総会
    • Place of Presentation
      札幌
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591181
  • [Presentation] Acyclic retinoidによるがん休眠維持作用2005

    • Author(s)
      大澤 一郎、村上 孝、小林 英司
    • Organizer
      第64回日本癌学会学術総会
    • Place of Presentation
      札幌
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591181
  • [Presentation] ヒストン脱アセチル化阻害剤を用いたラット腎癌モデルにおける腫瘍特異的遺伝子発現増強効果2005

    • Author(s)
      小林 実、森田 辰男、岡田 尚巳、小沢 敬也、村上 孝、小林 英司
    • Organizer
      第64回日本癌学会学術総会
    • Place of Presentation
      札幌
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591181
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