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Suga Hiroaki  菅 裕明

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SUGA Hiroaki  菅 裕明

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Researcher Number 00361668
Other IDs
Affiliation (Current) 2025: 東京大学, 大学院理学系研究科(理学部), 教授
Affiliation (based on the past Project Information) *help 2016 – 2025: 東京大学, 大学院理学系研究科(理学部), 教授
2021: 東京大学, 大学院理学系研究科, 教授
2017: 東京大学, 大学院理学研究科, 教授
2016: 東京大学, 理学系研究科, 教授
2014 – 2016: 東京大学, 理学(系)研究科(研究院), 教授 … More
2012 – 2016: 東京大学, 大学院理学系研究科, 教授
2014: 東京大学, 大学院理学系研究科(理学部), 教授
2010 – 2013: 東京大学, 大学院・理学系研究科, 教授
2004 – 2009: 東京大学, 先端科学技術研究センター, 教授
2007: The University of Tokyo, Research Center for Advanced Science and Technology, Professor
2005 – 2007: 東京大学, 先端化学技術研究センター, 教授 Less
Review Section/Research Field
Principal Investigator
Basic Section 37010:Bio-related chemistry / Basic Section 37030:Chemical biology-related / Basic Section 37020:Chemistry and chemical methodology of biomolecules-related / Bio-related chemistry / Chemical biology / ケミカルバイオロジー / Biomolecular chemistry / Science and Engineering / Living organism molecular science / Drug development chemistry / ケミカルバイオロジー / Science and Engineering / Chemistry … More
Except Principal Investigator
… More Urology / Science and Engineering / Structural biochemistry / Infectious disease medicine / Biophysics / Functional biochemistry / Experimental pathology / Conservative dentistry / Virology Less
Keywords
Principal Investigator
翻訳 / ペプチド / 特殊ペプチド / ケミカルバイオロジー / リボザイム / RaPID / tRNAアルシ化 / 遺伝記号 / 薬剤探索 / mRNA display … More / 擬天然物 / 天然物 / 遺伝暗号 / RNA / proteasomal degradation / cancer therapy / Ubiquitin / Genetic code expansion / Ribosomal translation / RNA synthesis / Unnatural nucleotide / RaPID system / Cysteine / Disulfide bond / OPA / peptide cyclization / Cross-coupling chemistry / masking of polar groups / Bioorthogonal chemistry / macrocylic peptides / lasso-graft / peptide / KRas / grafting / protein engineering / Macrocyclic peptides / Foldamers / FIT system / infectious diseases / macrocyclic peptide / infectious deseases / macrocyclic pepide / quorum sensing / RaPID System / ホウ素中性子 / hEGFR / Cba / Bpa / macrocyclic peptides / BNCT / 環状ペプチド / チアゾール / thioamide / translation / mRNA / inhibitor / RaPID selection / ABC-transporter / membrane protein / Macrocycles / Peptides / チオオキシカルボン酸カルボン酸 / tRNAアシル化 / チオオキシカルボン酸 / リボソーム / アミノ酸 / トランスポーター / キモカイン / 人工触媒 / ペルチド / 糖転移 / 人口触媒 / シアリダーゼ / コロナウィルス / コロナウイルス / 酵素 / 試験管内リデザイン生合成系 / 人工生合成系 / 主鎖修飾型ペプチド / 試験管内リデザイン整合性系 / 翻訳合成 / 生合成 / 創薬 / タンパク質合成 / 生化学 / 生体高分子 / 生理活性物質 / 天然物有機化学 / 酸化還元酵素 / アセチルCoA / 生命体 / 分子進化工学 / 脂質膜 / 生命の起源 / 試験管内進化 / バイオテクノロジー / RNAワールド / RNA触媒 / 分子進化 / RNA 触媒 … More
Except Principal Investigator
スクリーニング / 抗バイオフィルム剤 / バイオフィルム / シグナル伝達 / 癌 / 生物分子科学 / 天然物化学 / 生合成工学 / 合成生物学 / 生合成リデザイン / Eikenella corrodens / modified Robbins device / 特殊環状ペプチド / クオラムセンシング / クォーラムセンシング / 緑膿菌 / 蛋白質 / G蛋白質共役型受容体 / タンパク質 / Gタンパク質共役型受容体 / 結晶構造解析 / リアルタイムイメージング / リード化合物 / 抗菌薬抵抗性 / オートインデューサーアナログ / クオラムセンシング阻害剤 / 治療 / 難治性感染症 / 化学発光タンパク質 / ケミルミノジェネティクス / 発光基質 / オプトジェネティクス / 光感受性タンパク質 / 発光タンパク質 / MET / HGF / ペプチド / 増殖因子 / 増殖因子受容体 / サイトカイン / 受容体 / チロシンキナーゼ / 細胞増殖因子 / エピゲノム / 遺伝子 / トランスレーショナルリサーチ / ヒストンメチル化 / ペプチドライブラリ / 白血病 / エピドラッグ / 生物分子化学 / LuxS gene / Antagonist / Porphyromonas gingivalie / Oral biofilm / Autoinducer / Quorum sensing / 根尖孔外 / 根尖性歯周炎 / Modified Robbins device / 細胞外マトリックス / 赤血球凝集 / 共焦点レーザー顕微鏡 / アシルホモセリンラクトン / Porhyromonas gingivalis / 細胞密度感知機構 / LuxS遺伝子 / アンタゴニスト / Porphyromonas gingivalis / オーラルバイオフィルム / オートインデューサー / 増殖阻害 / パントロピック / 抗ウイルス剤 / HA蛋白質 / インフルエンザウイルス / 感染阻害 / インフルエンザ / 新規治療法 / アウトブレイク / 多剤耐性菌 / アシネトバクター / 感染症 / 細菌 / in vivo実験モデル系 / in vitro実験モデル系 / 日和見感染菌 / 難治性尿路感染症 / フローセル / 実験モデル系 / 尿路感染症 Less
  • Research Projects

    (36 results)
  • Research Products

    (515 results)
  • Co-Researchers

    (102 People)
  •  タンパク質へ特異的に共有結合を形成する薬剤の迅速発見Principal Investigator

    • Principal Investigator
      菅 裕明
    • Project Period (FY)
      2025 – 2026
    • Research Category
      Grant-in-Aid for JSPS Fellows
    • Review Section
      Basic Section 37020:Chemistry and chemical methodology of biomolecules-related
    • Research Institution
      The University of Tokyo
  •  擬天然物ライブラリーを用いた細胞膜透過性生理活性化合物の発見Principal Investigator

    • Principal Investigator
      菅 裕明
    • Project Period (FY)
      2024 – 2025
    • Research Category
      Grant-in-Aid for JSPS Fellows
    • Review Section
      Basic Section 37010:Bio-related chemistry
    • Research Institution
      The University of Tokyo
  •  光感受性ペプチド阻害剤を高速発見するプラットフォーム技術の開発Principal Investigator

    • Principal Investigator
      菅 裕明
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for JSPS Fellows
    • Review Section
      Basic Section 37010:Bio-related chemistry
    • Research Institution
      The University of Tokyo
  •  医薬品応用に向けた新奇ジスルフィドリッチペプチドのデザイン戦略Principal Investigator

    • Principal Investigator
      菅 裕明
    • Project Period (FY)
      2023 – 2024
    • Research Category
      Grant-in-Aid for JSPS Fellows
    • Review Section
      Basic Section 37020:Chemistry and chemical methodology of biomolecules-related
    • Research Institution
      The University of Tokyo
  •  天然遺伝暗号の拡張によるペプチドミメティックスの翻訳合成Principal Investigator

    • Principal Investigator
      菅 裕明
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for JSPS Fellows
    • Review Section
      Basic Section 37030:Chemical biology-related
    • Research Institution
      The University of Tokyo
  •  疾患原因タンパク質を分解するUボディによる新規創薬戦略Principal Investigator

    • Principal Investigator
      菅 裕明
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for JSPS Fellows
    • Review Section
      Basic Section 37030:Chemical biology-related
    • Research Institution
      The University of Tokyo
  •  抗KRAS環状ペプチドファマコフォアの小型タンパク質へのラソグラフト体の創出Principal Investigator

    • Principal Investigator
      菅 裕明
    • Project Period (FY)
      2022 – 2023
    • Research Category
      Grant-in-Aid for JSPS Fellows
    • Review Section
      Basic Section 37020:Chemistry and chemical methodology of biomolecules-related
    • Research Institution
      The University of Tokyo
  •  特殊ペプチド・フォールダマーハイブリッド分子の研究Principal Investigator

    • Principal Investigator
      菅 裕明
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for JSPS Fellows
    • Review Section
      Basic Section 37030:Chemical biology-related
    • Research Institution
      The University of Tokyo
  •  O-フタルアルデヒド基を用いたペプチドの高効率マクロ環化とその応用Principal Investigator

    • Principal Investigator
      菅 裕明
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for JSPS Fellows
    • Review Section
      Basic Section 37010:Bio-related chemistry
    • Research Institution
      The University of Tokyo
  •  Challenges to the remaining issues of therapeutically valuable pseudo-natural peptides and productsPrincipal Investigator

    • Principal Investigator
      菅 裕明
    • Project Period (FY)
      2020 – 2024
    • Research Category
      Grant-in-Aid for Specially Promoted Research
    • Review Section
      Science and Engineering
    • Research Institution
      The University of Tokyo
  •  ペプチドセレクションによる酵素ミミック創薬のための戦略Principal Investigator

    • Principal Investigator
      菅 裕明
    • Project Period (FY)
      2018
    • Research Category
      Grant-in-Aid for JSPS Fellows
    • Research Field
      Bio-related chemistry
    • Research Institution
      The University of Tokyo
  •  Redesigning Biosynthetic Machineries (Project Team)

    • Principal Investigator
      Abe Ikuro
    • Project Period (FY)
      2016 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Science and Engineering
    • Research Institution
      The University of Tokyo
  •  Redesigning Biosynthetic Machineries (International Activity Support Team)

    • Principal Investigator
      Abe Ikuro
    • Project Period (FY)
      2016 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Science and Engineering
    • Research Institution
      The University of Tokyo
  •  Synthetic biology of pseudo-natural products by artificial in vitro biosynthesisPrincipal Investigator

    • Principal Investigator
      菅 裕明
    • Project Period (FY)
      2016 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Science and Engineering
    • Research Institution
      The University of Tokyo
  •  チアゾール含有環状ペプチドの翻訳合成法Principal Investigator

    • Principal Investigator
      菅 裕明
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for JSPS Fellows
    • Research Field
      Chemical biology
    • Research Institution
      The University of Tokyo
  •  中性子捕捉療法を指向したホウ素含有環状ペプチドの開発Principal Investigator

    • Principal Investigator
      菅 裕明
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for JSPS Fellows
    • Research Field
      Drug development chemistry
    • Research Institution
      The University of Tokyo
  •  抗菌作用を発揮する大環状特殊ペプチドの発見と開発Principal Investigator

    • Principal Investigator
      菅 裕明
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for JSPS Fellows
    • Research Field
      Bio-related chemistry
    • Research Institution
      The University of Tokyo
  •  Signal characteristics of heatero-receptor coupling and generation of artificial ligand

    • Principal Investigator
      Matsumoto Kunio
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Functional biochemistry
    • Research Institution
      Kanazawa University
  •  Trial for determining the structure of CXCR7

    • Principal Investigator
      Shimamura Tatsuro
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Structural biochemistry
    • Research Institution
      Kyoto University
  •  薬剤活性向上した大環状ペプチドを開発する新規戦略Principal Investigator

    • Principal Investigator
      菅 裕明
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for JSPS Fellows
    • Research Field
      Chemical biology
    • Research Institution
      The University of Tokyo
  •  Innovation of chemiluminogenetics capable of noninvasive manipulation of biological functions deep inside body

    • Principal Investigator
      Nagai Takeharu
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Biophysics
    • Research Institution
      Osaka University
  •  Generation of minimal peptide catalysts based on the macrocyclic scaffoldPrincipal Investigator

    • Principal Investigator
      Suga Hiroaki
    • Project Period (FY)
      2014 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Biomolecular chemistry
    • Research Institution
      The University of Tokyo
  •  プロリル-4-ヒドロキシダーゼをアイソフォーム選択的に阻害する大環状化合物の発見Principal Investigator

    • Principal Investigator
      菅 裕明
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for JSPS Fellows
    • Research Field
      Biomolecular chemistry
    • Research Institution
      The University of Tokyo
  •  Influenza viral hemagglutinin-targeted macrocyclic peptides as an antiviral agent

    • Principal Investigator
      KOHARA Michinori
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Virology
    • Research Institution
      Tokyo Metropolitan Institute of Medical Science
  •  Development of PPIs for a histone methyltransferase for leukemia therapy

    • Principal Investigator
      OKADA YUKI
    • Project Period (FY)
      2013 – 2016
    • Research Category
      Grant-in-Aid for Young Scientists (A)
    • Research Field
      Experimental pathology
    • Research Institution
      The University of Tokyo
  •  Analyses of mechanism of action of a quorum sensing inhibitor by using real-time imaging system

    • Principal Investigator
      KARIYAMA REIKO
    • Project Period (FY)
      2013 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Infectious disease medicine
    • Research Institution
      Okayama Gakuin University
      Okayama University
  •  低酸素誘導因子を阻害する特殊ペプチドの創出Principal Investigator

    • Principal Investigator
      菅 裕明
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for JSPS Fellows
    • Research Field
      ケミカルバイオロジー
    • Research Institution
      The University of Tokyo
  •  Keap1-Nrf2の相互作用を阻害する擬天然物特殊ペプチドのプロドラッグ化Principal Investigator

    • Principal Investigator
      菅 裕明
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for JSPS Fellows
    • Research Field
      ケミカルバイオロジー
    • Research Institution
      The University of Tokyo
  •  チオオキシ主鎖骨格ペプチドの翻訳合成技術の開発Principal Investigator

    • Principal Investigator
      菅 裕明
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for JSPS Fellows
    • Research Field
      ケミカルバイオロジー
    • Research Institution
      The University of Tokyo
  •  Development of novel methods for identifying antibiofilm agents against multidrug-resistant Acinetobacter baumannii

    • Principal Investigator
      KUMON Hiromi
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Urology
    • Research Institution
      Okayama University
  •  Non-standard peptide-probe discoveryPrincipal Investigator

    • Principal Investigator
      SUGA Hiroaki
    • Project Period (FY)
      2009 – 2013
    • Research Category
      Grant-in-Aid for Specially Promoted Research
    • Review Section
      Science and Engineering
      Chemistry
    • Research Institution
      The University of Tokyo
  •  擬天然物の翻訳プログラム合成と薬剤探索Principal Investigator

    • Principal Investigator
      菅 裕明
    • Project Period (FY)
      2009
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Living organism molecular science
    • Research Institution
      The University of Tokyo
  •  Persistent biofilms in urinary tract infections -the development of novel methods for identifying antibiofilm agents-

    • Principal Investigator
      UEHARA Shinya, 門田 晃一
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Urology
    • Research Institution
      Okayama University
  •  Pseudomonas aeruginosa biofilms in urinary tract infections-the development of novelmethods for the search of antibiofilm agents-

    • Principal Investigator
      KARIYAMA Reiko
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Okayama University
  •  The study on control technique of oral biofilms using a quorum sensing circuit

    • Principal Investigator
      SHIGEYUKI Ebisu
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Conservative dentistry
    • Research Institution
      Osaka University
  •  Generation of ribozymes that catalyze fatty acid biosynthesisPrincipal Investigator

    • Principal Investigator
      SUGA Hiroaki
    • Project Period (FY)
      2004 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Living organism molecular science
    • Research Institution
      The University of Tokyo

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 Other

All Journal Article Presentation Book Patent

  • [Book] 遺伝暗号リプログラミングによる人工翻訳系の創製、人工細胞の創製とその応用2017

    • Author(s)
      黒田知宏, 後藤佑樹, 菅裕明
    • Total Pages
      215
    • Publisher
      シーエムシー出版
    • Data Source
      KAKENHI-PLANNED-16H06444
  • [Book] 特殊ペプチド創薬~第三の創薬シーズの可能性を拓く~、現代化学2016

    • Author(s)
      山田光博, 梅本詩織, 後藤佑樹, 菅裕明
    • Total Pages
      80
    • Publisher
      東京化学同人
    • Data Source
      KAKENHI-PLANNED-16H06444
  • [Book] 最新ペプチド合成技術とその創薬研究への応用2012

    • Author(s)
      伊藤悠美、後藤佑樹、菅裕明
    • Publisher
      メディカルドゥ
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Book] Metal Ions in Life Sciences: Structural and Catalytic Roles of Metal Ions in RNA “Metal ion requirements in artificial ribozymes that catalyze aminoacylation and red-ox reactions”2012

    • Author(s)
      H. Suga, K. Futai, K. Jin
    • Publisher
      RSC Publishing
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Book] Methods in Molecular Biology 848: Ribozymes Methods and Protocols “Flexizymes as a tRNA acylation tool facilitating genetic code reprogramming”2012

    • Author(s)
      Y. Goto, H. Suga
    • Publisher
      Humana Press
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Book] Metal Ions in Life Sciences : Structural and Catalytic Roles of Metal Ions in RNA "Metal ion requirements in artificial ribozymes that catalyze aminoacylation and redox reactions"2012

    • Author(s)
      H.Suga, K.Futai, K.Jin
    • Publisher
      RSC Publishing
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Book] Methods in Molecular Biology 805 : Ribosome Display and Related Technologies "Charging of tRNAs using ribozymes and selection of cyclic peptides containing thioethers"2012

    • Author(s)
      P.Reid, Y.Goto, T.Katoh, H.Suga
    • Publisher
      Humana Press
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Book] Methods in Molecular Biology 848 : Ribozymes Methods and Protocols "Flexizymesas a tRNA acylation tool facilitating genetic code reprogramming"2012

    • Author(s)
      Y.Goto, H.Suga
    • Publisher
      Humana Press
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Book] Methods in Molecular Biology 805: Ribosome Display and Related Technologies “Charging of tRNAs using ribozymes and selection of cyclic peptides containing thioethers”2012

    • Author(s)
      P. Reid, Y. Goto, T. Katoh, H. Suga
    • Publisher
      Humana Press
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Book] 核酸化学のニュートレンド2011

    • Author(s)
      後藤佑樹、菅裕明
    • Publisher
      化学同人
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Book] Quorum Sensing : Chapter 19 "Custom synthesis of antoinducers and their analogues"2010

    • Author(s)
      J.Igarashi, H.Suga
    • Publisher
      Humane Press
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Book] 鳥飼浩平2009

    • Author(s)
      鳥飼浩平・菅裕明
    • Publisher
      ファルマシア
    • Data Source
      KAKENHI-PROJECT-16101007
  • [Book] セルアラカルト : ケミカルバイオロジーの夜明けから20年、潮流が大きな波に変わるには2009

    • Author(s)
      菅裕明
    • Publisher
      細胞工学
    • Data Source
      KAKENHI-PROJECT-16101007
  • [Book] 「特殊ペプチドの翻訳合成と薬剤探索」新規素材探索-医薬品リード化合物・食品素材を求めて-2008

    • Author(s)
      菅裕明・山岸祐介
    • Publisher
      シーエムシー出版
    • Data Source
      KAKENHI-PROJECT-16101007
  • [Book] 新創薬技術RAPIDシステムとマイクロ・ナノディバイスへの期待2008

    • Author(s)
      村上裕・菅裕明
    • Publisher
      化学工業
    • Data Source
      KAKENHI-PROJECT-16101007
  • [Journal Article] A Compact Reprogrammed Genetic Code for De Novo Discovery of Proteolytically Stable Thiopeptides2024

    • Author(s)
      Vinogradov Alexander A.、Zhang Yue、Hamada Keisuke、Kobayashi Shunsuke、Ogata Kazuhiro、Sengoku Toru、Goto Yuki、Suga Hiroaki
    • Journal Title

      Journal of the American Chemical Society

      Volume: 146 Issue: 12 Pages: 8058-8070

    • DOI

      10.1021/jacs.3c12037

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22KF0114, KAKENHI-ORGANIZER-21H05158, KAKENHI-PLANNED-21H05161
  • [Journal Article] In vitro selection of macrocyclic peptide inhibitors containing cyclic γ2,4-amino acids targeting the SARS-CoV-2 main protease2023

    • Author(s)
      Takashi Miura, Tika Malla, David Owen, Anthony Tumber, Lennart Brewitz, Michael McDonough, Eidarus Salah, Naohiro Terasaka, Takayuki Katoh, Petra Lukacik, Claire Strain-Damerell, Halina Mikolajek, Martin Walsh, Akane Kawamura, Christopher Schofield, Hiroaki Suga
    • Journal Title

      Nature Chemistry

      Volume: 15 Issue: 7 Pages: 998-1005

    • DOI

      10.1038/s41557-023-01205-1

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22KJ0868, KAKENHI-PROJECT-20H05618
  • [Journal Article] Discovery and characterization of cyclic peptides selective for the C-terminal bromodomains of BET family proteins2023

    • Author(s)
      Franck Charlotte、Patel Karishma、Walport Louise J.、Christie Mary、Norman Alexander、Passioura Toby、Suga Hiroaki、Payne Richard J.、Mackay Joel P.
    • Journal Title

      Structure

      Volume: 31 Issue: 8 Pages: 912-923.e4

    • DOI

      10.1016/j.str.2023.05.009

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H05618
  • [Journal Article] Translation initiation with exotic amino acids using EF-P-responsive artificial initiator tRNA2023

    • Author(s)
      Katoh Takayuki、Suga Hiroaki
    • Journal Title

      Nucleic Acids Research

      Volume: 51 Issue: 15 Pages: 8169-8180

    • DOI

      10.1093/nar/gkad496

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K18233, KAKENHI-PROJECT-20H05618, KAKENHI-PROJECT-22H00439
  • [Journal Article] Structural basis of tRNAPro acceptor stem recognition by a bacterial <i>trans</i>-editing domain2023

    • Author(s)
      Ma Xiao、Bakhtina Marina、Shulgina Irina、Cantara William A、Kuzmishin?Nagy Alexandra?B、Goto Yuki、Suga Hiroaki、Foster Mark P、Musier-Forsyth Karin
    • Journal Title

      Nucleic Acids Research

      Volume: 51 Issue: 8 Pages: 3988-3999

    • DOI

      10.1093/nar/gkad192

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H05618
  • [Journal Article] Discovery, biochemical characterization, and bioengineering of cyanobactin prenyltransferases2023

    • Author(s)
      Zhang Yuchen、Goto Yuki、Suga Hiroaki
    • Journal Title

      Trends in Biochemical Sciences

      Volume: 48 Issue: 4 Pages: 360-374

    • DOI

      10.1016/j.tibs.2022.11.002

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20H05618
  • [Journal Article] Two-Chain Mature Hepatocyte Growth Factor-Specific Positron Emission Tomography Imaging in Tumors Using 64Cu-Labeled HiP-8, a Nonstandard Macrocyclic Peptide Probe2023

    • Author(s)
      Shota Warashina , Hiroki Sato, Maki Zouda, Maiko Takahashi, Yasuhiro Wada, Toby Passioura, Hiroaki Suga, Yasuyoshi Watanabe, Kunio Matsumoto, Hidefumi Mukai
    • Journal Title

      Molecular Pharmaceutics

      Volume: 20(4) Issue: 4 Pages: 2029-2038

    • DOI

      10.1021/acs.molpharmaceut.2c01020

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K15482, KAKENHI-PROJECT-21K18250, KAKENHI-PROJECT-20H05618
  • [Journal Article] A RaPID Macrocyclic Peptide That Inhibits the Formation of α‐Synuclein Amyloid Fibrils2023

    • Author(s)
      Ikenoue Tatsuya、Oono Miki、So Masatomo、Yamakado Hodaka、Arata Toshiaki、Takahashi Ryosuke、Kawata Yasushi、Suga Hiroaki
    • Journal Title

      ChemBioChem

      Volume: 24 Issue: 12

    • DOI

      10.1002/cbic.202300320

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20H05618
  • [Journal Article] Ribosomal Synthesis of Peptides Bearing Noncanonical Backbone Structures via Chemical Posttranslational Modifications2023

    • Author(s)
      Goto Yuki、Suga Hiroaki
    • Journal Title

      Methods Mol Biol

      Volume: - Pages: 255-266

    • DOI

      10.1007/978-1-0716-3214-7_13

    • ISBN
      9781071632130, 9781071632147
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20H05618
  • [Journal Article] Combining Chemical Protein Synthesis and Random Nonstandard Peptides Integrated Discovery for Modulating Biological Processes2023

    • Author(s)
      Saha Abhishek、Suga Hiroaki、Brik Ashraf
    • Journal Title

      Accounts of Chemical Research

      Volume: 56 Issue: 14 Pages: 1953-1965

    • DOI

      10.1021/acs.accounts.3c00178

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H05618
  • [Journal Article] MET-activating ubiquitin multimers.2023

    • Author(s)
      Kawakami N, Sato H, Terasaka N, Matsumoto K, Suga H.
    • Journal Title

      Angewandte Chemie, International Edition

      Volume: 62 Issue: 36

    • DOI

      10.1002/anie.202307157

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K18250, KAKENHI-PROJECT-20H05618
  • [Journal Article] Solid-Phase-Based Synthesis of Lactazole-Like Thiopeptides2022

    • Author(s)
      Zhang Yue、Vinogradov Alexander A.、Chang Jun Shi、Goto Yuki、Suga Hiroaki
    • Journal Title

      Organic Letters

      Volume: 24 Issue: 43 Pages: 7894-7899

    • DOI

      10.1021/acs.orglett.2c02870

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H05618, KAKENHI-PROJECT-22KF0114
  • [Journal Article] Selective macrocyclic peptide modulators of Lys63-linked ubiquitin chains disrupt DNA damage repair2022

    • Author(s)
      Vamisetti Ganga B.、Saha Abhishek、Huang Yichao J.、Vanjari Rajeshwer、Mann Guy、Gutbrod Julia、Ayoub Nabieh、Suga Hiroaki、Brik Ashraf
    • Journal Title

      Nature Communications

      Volume: 13 Issue: 1

    • DOI

      10.1038/s41467-022-33808-6

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H05618
  • [Journal Article] Designing receptor agonists with enhanced pharmacokinetics by grafting macrocyclic peptides into fragment crystallizable regions2022

    • Author(s)
      Sakai Katsuya、Sugano-Nakamura Nozomi、Mihara Emiko、Rojas-Chaverra Nichole Marcela、Watanabe Sayako、Sato Hiroki、Imamura Ryu、Voon Dominic Chih-Cheng、Sakai Itsuki、Yamasaki Chihiro、Tateno Chise、Shibata Mikihiro、Suga Hiroaki、Takagi Junichi、Matsumoto Kunio
    • Journal Title

      Nature Biomedical Engineering

      Volume: 7 Issue: 2 Pages: 164-176

    • DOI

      10.1038/s41551-022-00955-6

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K18250, KAKENHI-PROJECT-21K15482, KAKENHI-PROJECT-20H05618, KAKENHI-PROJECT-20H00455, KAKENHI-PROJECT-21H01771, KAKENHI-PROJECT-20K06553, KAKENHI-PUBLICLY-21H00247
  • [Journal Article] State-selective modulation of heterotrimeric Gαs signaling with macrocyclic peptides2022

    • Author(s)
      Dai Shizhong A.、Hu Qi、Gao Rong、Blythe Emily E.、Touhara Kouki K.、Peacock Hayden、Zhang Ziyang、von Zastrow Mark、Suga Hiroaki、Shokat Kevan M.
    • Journal Title

      Cell

      Volume: 185 Issue: 21 Pages: 3950-3965.e25

    • DOI

      10.1016/j.cell.2022.09.019

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H05618
  • [Journal Article] In Vitro Selection of Macrocyclic α/β3-Peptides against Human EGFR2022

    • Author(s)
      Wakabayashi Risa、Kawai Marina、Katoh Takayuki、Suga Hiroaki
    • Journal Title

      Journal of the American Chemical Society

      Volume: 144 Issue: 40 Pages: 18504-18510

    • DOI

      10.1021/jacs.2c07624

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K18233, KAKENHI-PROJECT-20H05618, KAKENHI-PROJECT-22H00439, KAKENHI-PROJECT-21J11468
  • [Journal Article] Potent macrocycle inhibitors of the human SAGA deubiquitinating module2022

    • Author(s)
      Morgan Michael、Ikenoue Tatsuya、Suga Hiroaki、Wolberger Cynthia
    • Journal Title

      Cell Chemical Biology

      Volume: 29 Issue: 4 Pages: 544-554.e4

    • DOI

      10.1016/j.chembiol.2021.12.004

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H05618
  • [Journal Article] Drop-off-reinitiation triggered by EF-G-driven mistranslocation and its alleviation by EF-P2022

    • Author(s)
      Tajima Kenya、Katoh Takayuki、Suga Hiroaki
    • Journal Title

      Nucleic Acids Research

      Volume: 50 Issue: 5 Pages: 2736-2753

    • DOI

      10.1093/nar/gkac068

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H02080, KAKENHI-PROJECT-20H05618
  • [Journal Article] Inner residues of macrothiolactone in autoinducer peptides I/IV circumvent spontaneous <i>S</i>-to-<i>O</i> acyl transfer to the upstream serine residue2022

    • Author(s)
      Nagano Masanobu、Ishida Satoshi、Suga Hiroaki
    • Journal Title

      RSC Chemical Biology

      Volume: 3 Issue: 3 Pages: 295-300

    • DOI

      10.1039/d1cb00225b

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H05618
  • [Journal Article] LimF is a versatile prenyltransferase for histidine-C-geranylation on diverse non-natural substrates2022

    • Author(s)
      Zhang Yuchen、Hamada Keisuke、Nguyen Dinh Thanh、Inoue Sumika、Satake Masayuki、Kobayashi Shunsuke、Okada Chikako、Ogata Kazuhiro、Okada Masahiro、Sengoku Toru、Goto Yuki、Suga Hiroaki
    • Journal Title

      Nature Catalysis

      Volume: 5 Issue: 8 Pages: 682-693

    • DOI

      10.1038/s41929-022-00822-2

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K06051, KAKENHI-PROJECT-21K19056, KAKENHI-PROJECT-20H05618, KAKENHI-ORGANIZER-21H05158, KAKENHI-PROJECT-19H02842, KAKENHI-PLANNED-21H05161
  • [Journal Article] Potent De Novo Macrocyclic Peptides That Inhibit O‐GlcNAc Transferase through an Allosteric Mechanism2022

    • Author(s)
      Alteen Matthew G.、Peacock Hayden、Meek Richard W.、Busmann Jil A.、Zhu Sha、Davies Gideon J.、Suga Hiroaki、Vocadlo David J.
    • Journal Title

      Angewandte Chemie International Edition

      Volume: 62 Issue: 5

    • DOI

      10.1002/anie.202215671

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H05618
  • [Journal Article] De novo Fc-based receptor dimerizers differentially modulate PlexinB1 function2022

    • Author(s)
      Sugano-Nakamura Nozomi、Matoba Kyoko、Hirose Mika、Bashiruddin Nasir K.、Matsunaga Yukiko、Yamashita Keitaro、Hirata Kunio、Yamamoto Masaki、Arimori Takao、Suga Hiroaki、Takagi Junichi
    • Journal Title

      Structure

      Volume: 30 Issue: 10 Pages: 1411-1423.e4

    • DOI

      10.1016/j.str.2022.07.008

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20H05618, KAKENHI-PROJECT-20H00455, KAKENHI-PROJECT-23K21290
  • [Journal Article] In Vitro Genetic Code Reprogramming for the Expansion of Usable Noncanonical Amino Acids2022

    • Author(s)
      Katoh Takayuki、Suga Hiroaki
    • Journal Title

      Annual Review of Biochemistry

      Volume: 91 Issue: 1 Pages: 221-243

    • DOI

      10.1146/annurev-biochem-040320-103817

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K18233, KAKENHI-PROJECT-20H05618, KAKENHI-PROJECT-22H00439
  • [Journal Article] A context-dependent and disordered ubiquitin-binding motif2022

    • Author(s)
      Dreier Jesper E.、Prestel Andreas、Martins Joao M.、Brondum Sebastian S.、Nielsen Olaf、Garbers Anna E.、Suga Hiroaki、Boomsma Wouter、Rogers Joseph M.、Hartmann-Petersen Rasmus、Kragelund Birthe B.
    • Journal Title

      Cellular and Molecular Life Sciences

      Volume: 79 Issue: 9

    • DOI

      10.1007/s00018-022-04486-w

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H05618
  • [Journal Article] Post-translational backbone-acyl shift yields natural product-like peptides bearing hydroxyhydrocarbon units2022

    • Author(s)
      Kuroda Tomohiro、Huang Yichao、Nishio Soichiro、Goto Yuki、Suga Hiroaki
    • Journal Title

      Nature Chemistry

      Volume: 14 Issue: 12 Pages: 1413-1420

    • DOI

      10.1038/s41557-022-01065-1

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H05618
  • [Journal Article] Accurate Models of Substrate Preferences of Post-Translational Modification Enzymes from a Combination of mRNA Display and Deep Learning2022

    • Author(s)
      Vinogradov Alexander A.、Chang Jun Shi、Onaka Hiroyasu、Goto Yuki、Suga Hiroaki
    • Journal Title

      ACS Central Science

      Volume: 8 Issue: 6 Pages: 814-824

    • DOI

      10.1021/acscentsci.2c00223

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H05618, KAKENHI-PROJECT-21H04712
  • [Journal Article] De Novo Discovery of Thiopeptide Pseudo-natural Products Acting as Potent and Selective TNIK Kinase Inhibitors2022

    • Author(s)
      Vinogradov Alexander A.、Zhang Yue、Hamada Keisuke、Chang Jun Shi、Okada Chikako、Nishimura Hirotaka、Terasaka Naohiro、Goto Yuki、Ogata Kazuhiro、Sengoku Toru、Onaka Hiroyasu、Suga Hiroaki
    • Journal Title

      Journal of the American Chemical Society

      Volume: 144 Issue: 44 Pages: 20332-20341

    • DOI

      10.1021/jacs.2c07937

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K06051, KAKENHI-PROJECT-20H05618, KAKENHI-ORGANIZER-21H05158, KAKENHI-PROJECT-21H04712, KAKENHI-PROJECT-22KF0114, KAKENHI-PLANNED-21H05161
  • [Journal Article] Phosphine addition to dehydroalanine for peptide modification2022

    • Author(s)
      Liu Minglong、Sovrovic Miha、Suga Hiroaki、Jongkees Seino A. K.
    • Journal Title

      Organic &amp; Biomolecular Chemistry

      Volume: 20 Issue: 15 Pages: 3081-3085

    • DOI

      10.1039/d2ob00410k

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H05618
  • [Journal Article] In Vitro Selection of Foldamer-Like Macrocyclic Peptides Containing 2-Aminobenzoic Acid and 3-Aminothiophene-2-Carboxylic Acid2022

    • Author(s)
      Katoh Takayuki、Suga Hiroaki
    • Journal Title

      Journal of the American Chemical Society

      Volume: 144 Issue: 5 Pages: 2069-2072

    • DOI

      10.1021/jacs.1c12133

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20H05618, KAKENHI-PROJECT-18H02080, KAKENHI-PROJECT-21K18233
  • [Journal Article] Structure?activity relationship of ipglycermide binding to phosphoglycerate mutases2021

    • Author(s)
      Wiedmann Mareike、Dranchak Patricia K.、Aitha Mahesh、Queme Bryan、Collmus Christopher D.、Kashipathy Maithri M.、Kanter Liza、Lamy Laurence、Rogers Joseph M.、Tao Dingyin、Battaile Kevin P.、Rai Ganesha、Lovell Scott、Suga Hiroaki、Inglese James
    • Journal Title

      Journal of Biological Chemistry

      Volume: 296 Pages: 100628-100628

    • DOI

      10.1016/j.jbc.2021.100628

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H05618
  • [Journal Article] One-Pot <i>In Vitro</i> Ribosomal Synthesis of Macrocyclic Depsipeptides2021

    • Author(s)
      Nagano Masanobu、Huang Yichao、Obexer Richard、Suga Hiroaki
    • Journal Title

      Journal of the American Chemical Society

      Volume: 143 Issue: 12 Pages: 4741-4750

    • DOI

      10.1021/jacs.1c00466

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H05618
  • [Journal Article] <i>In vivo</i> modulation of ubiquitin chains by <i>N</i>-methylated non-proteinogenic cyclic peptides2021

    • Author(s)
      Rogers Joseph M.、Nawatha Mickal、Lemma Betsegaw、Vamisetti Ganga B.、Livneh Ido、Barash Uri、Vlodavsky Israel、Ciechanover Aaron、Fushman David、Suga Hiroaki、Brik Ashraf
    • Journal Title

      RSC Chemical Biology

      Volume: 2 Issue: 2 Pages: 513-522

    • DOI

      10.1039/d0cb00179a

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H05618
  • [Journal Article] In Vitro Selection of Macrocyclic <scp>d</scp>/<scp>l</scp>-Hybrid Peptides against Human EGFR2021

    • Author(s)
      Imanishi Sayaka、Katoh Takayuki、Yin Yizhen、Yamada Mituhiro、Kawai Marina、Suga Hiroaki
    • Journal Title

      Journal of the American Chemical Society

      Volume: 143 Issue: 15 Pages: 5680-5684

    • DOI

      10.1021/jacs.1c02593

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H05618, KAKENHI-PROJECT-18H02080
  • [Journal Article] Lasso-grafting of macrocyclic peptide pharmacophores yields multi-functional proteins2021

    • Author(s)
      Mihara E, Watanabe S, Bashiruddin N, Nakamura N, Matoba K, Maini R, Yin Y, Sakai K, Arimori T, Matsumoto K, Suga H, and Takagi J.
    • Journal Title

      Nature Communications

      Volume: 12 Issue: 1 Pages: 1543-1543

    • DOI

      10.1038/s41467-021-21875-0

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H00455, KAKENHI-PROJECT-18H02389, KAKENHI-PROJECT-20H05618, KAKENHI-PROJECT-19H03499, KAKENHI-PROJECT-20K06553, KAKENHI-PROJECT-21K18250, KAKENHI-PROJECT-20K20581
  • [Journal Article] The Development of a Fluorescence‐Based Competitive Assay Enabled the Discovery of Dimeric Cyclic Peptide Modulators of Ubiquitin Chains2021

    • Author(s)
      Vamisetti Ganga B.、Meledin Roman、Nawatha Mickal、Suga Hiroaki、Brik Ashraf
    • Journal Title

      Angewandte Chemie International Edition

      Volume: 60 Issue: 13 Pages: 7018-7023

    • DOI

      10.1002/anie.202013392

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H05618
  • [Journal Article] Targeting of extracellular protein?protein interactions with macrocyclic peptides2021

    • Author(s)
      Taguchi Shota、Suga Hiroaki
    • Journal Title

      Current Opinion in Chemical Biology

      Volume: 62 Pages: 82-89

    • DOI

      10.1016/j.cbpa.2021.02.013

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20H05618
  • [Journal Article] Posttranslational chemical installation of azoles into translated peptides2021

    • Author(s)
      Tsutsumi Haruka、Kuroda Tomohiro、Kimura Hiroyuki、Goto Yuki、Suga Hiroaki
    • Journal Title

      Nature Communications

      Volume: 12 Issue: 1 Pages: 696-696

    • DOI

      10.1038/s41467-021-20992-0

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H05618, KAKENHI-PROJECT-19K22243, KAKENHI-PROJECT-20H02866
  • [Journal Article] Discovery of De Novo Macrocyclic Peptides by Messenger RNA Display2021

    • Author(s)
      Peacock Hayden、Suga Hiroaki
    • Journal Title

      Trends in Pharmacological Sciences

      Volume: 42 Issue: 5 Pages: 385-397

    • DOI

      10.1016/j.tips.2021.02.004

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H05618
  • [Journal Article] Affinity Maturation of Macrocyclic Peptide Modulators of Lys48‐Linked Diubiquitin by a Twofold Strategy2020

    • Author(s)
      Huang Yichao、Nawatha Mickal、Livneh Ido、Rogers Joseph M.、Sun Hao、Singh Sumeet K.、Ciechanover Aaron、Brik Ashraf、Suga Hiroaki
    • Journal Title

      Chemistry A European Journal

      Volume: 26 Issue: 36 Pages: 8022-8027

    • DOI

      10.1002/chem.202000273

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H05618, KAKENHI-PLANNED-16H06444
  • [Journal Article] Cyclic peptides can engage a single binding pocket through highly divergent modes2020

    • Author(s)
      Patel Karishma、Walport Louise J.、Walshe James L.、Solomon Paul D.、Low Jason K. K.、Tran Daniel H.、Mouradian Kevork S.、Silva Ana P. G.、Wilkinson-White Lorna、Norman Alexander、Franck Charlotte、Matthews Jacqueline M.、Guss J. Mitchell、Payne Richard J.、Passioura Toby、Suga Hiroaki、Mackay Joel P.
    • Journal Title

      Proceedings of the National Academy of Sciences

      Volume: 117 Issue: 43 Pages: 26728-26738

    • DOI

      10.1073/pnas.2003086117

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H05618
  • [Journal Article] Chemoenzymatic Posttranslational Modification Reactions for the Synthesis of Ψ[CH 2 NH]‐Containing Peptides2020

    • Author(s)
      Kato Yasuharu、Kuroda Tomohiro、Huang Yichao、Ohta Risa、Goto Yuki、Suga Hiroaki
    • Journal Title

      Angewandte Chemie International Edition

      Volume: 59 Issue: 2 Pages: 684-688

    • DOI

      10.1002/anie.201910894

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-16H06444, KAKENHI-PUBLICLY-18H04382, KAKENHI-PROJECT-19J14230, KAKENHI-PROJECT-20H05618, KAKENHI-PROJECT-19K22243, KAKENHI-PROJECT-17H04762
  • [Journal Article] Discovery of Potent Cyclic Sulfopeptide Chemokine Inhibitors via Reprogrammed Genetic Code mRNA Display2020

    • Author(s)
      Johansen-Leete Jason、Passioura Toby、Foster Simon R.、Bhusal Ram Prasad、Ford Daniel J.、Liu Minglong、Jongkees Seino A. K.、Suga Hiroaki、Stone Martin J.、Payne Richard J.
    • Journal Title

      Journal of the American Chemical Society

      Volume: 142 Issue: 20 Pages: 9141-9146

    • DOI

      10.1021/jacs.0c03152

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H05618
  • [Journal Article] Discovery of quorum quenchers targeting the membrane-embedded sensor domain of theStaphylococcus aureusreceptor histidine kinase, AgrC2020

    • Author(s)
      Xie Qian、Wiedmann Mareike M.、Zhao Aishan、Pagan Ivelisse R.、Novick Richard P.、Suga Hiroaki、Muir Tom W.
    • Journal Title

      Chemical Communications

      Volume: 56 Issue: 76 Pages: 11223-11226

    • DOI

      10.1039/d0cc04873a

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H05618
  • [Journal Article] Macrocyclic peptides that inhibit Wnt signallingviainteraction with Wnt3a2020

    • Author(s)
      Otero-Ramirez Manuel E.、Matoba Kyoko、Mihara Emiko、Passioura Toby、Takagi Junichi、Suga Hiroaki
    • Journal Title

      RSC Chemical Biology

      Volume: 1 Issue: 1 Pages: 26-34

    • DOI

      10.1039/d0cb00016g

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H05618, KAKENHI-PROJECT-20H00455, KAKENHI-PROJECT-20K20581
  • [Journal Article] GTP-State-Selective Cyclic Peptide Ligands of K-Ras(G12D) Block Its Interaction with Raf2020

    • Author(s)
      Zhang Ziyang、Gao Rong、Hu Qi、Peacock Hayden、Peacock D. Matthew、Dai Shizhong、Shokat Kevan M.、Suga Hiroaki
    • Journal Title

      ACS Central Science

      Volume: 6 Issue: 10 Pages: 1753-1761

    • DOI

      10.1021/acscentsci.0c00514

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H05618
  • [Journal Article] Initiating ribosomal peptide synthesis with exotic building blocks2020

    • Author(s)
      Tsiamantas Christos、Rogers Joseph M.、Suga Hiroaki
    • Journal Title

      Chemical Communications

      Volume: 56 Issue: 31 Pages: 4265-4272

    • DOI

      10.1039/d0cc01291b

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H05618, KAKENHI-PLANNED-16H06444
  • [Journal Article] Ribosomal Elongation of Cyclic γ-Amino Acids using a Reprogrammed Genetic Code2020

    • Author(s)
      Katoh Takayuki、Suga Hiroaki
    • Journal Title

      Journal of the American Chemical Society

      Volume: 142 Issue: 11 Pages: 4965-4969

    • DOI

      10.1021/jacs.9b12280

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18H02080, KAKENHI-PROJECT-20H05618
  • [Journal Article] Ribosomal Incorporation of Aromatic Oligoamides as Peptide Sidechain Appendages2020

    • Author(s)
      Tsiamantas Christos、Kwon Sunbum、Rogers Joseph M.、Douat Cline、Huc Ivan、Suga Hiroaki
    • Journal Title

      Angewandte Chemie International Edition

      Volume: 59 Issue: 12 Pages: 4860-4864

    • DOI

      10.1002/anie.201914654

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06444, KAKENHI-PROJECT-20H05618
  • [Journal Article] A Macrocyclic Peptide Library with a Structurally Constrained Cyclopropane‐containing Building Block Leads to Thiol‐independent Inhibitors of Phosphoglycerate Mutase2020

    • Author(s)
      Okuma Rika、Kuwahara Tomoki、Yoshikane Takafumi、Watanabe Mizuki、Dranchak Patricia、Inglese James、Shuto Satoshi、Goto Yuki、Suga Hiroaki
    • Journal Title

      Chemistry - An Asian Journal

      Volume: 15 Issue: 17 Pages: 2631-2636

    • DOI

      10.1002/asia.202000700

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K06965, KAKENHI-PROJECT-19H01014, KAKENHI-PROJECT-19K22243, KAKENHI-PLANNED-16H06444, KAKENHI-PROJECT-20H02866
  • [Journal Article] An aminoacylation ribozyme evolved from a natural tRNA-sensing T-box riboswitch2020

    • Author(s)
      Ishida Satoshi、Terasaka Naohiro、Katoh Takayuki、Suga Hiroaki
    • Journal Title

      Nature Chemical Biology

      Volume: 16 Issue: 6 Pages: 702-709

    • DOI

      10.1038/s41589-020-0500-6

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K16200, KAKENHI-PROJECT-20H05618, KAKENHI-PLANNED-16H06444
  • [Journal Article] Methodologies for Backbone Macrocyclic Peptide Synthesis Compatible With Screening Technologies2020

    • Author(s)
      Shinbara Koki、Liu Wenyu、van Neer Renier Herman Pieter、Katoh Takayuki、Suga Hiroaki
    • Journal Title

      Frontiers in Chemistry

      Volume: 8 Pages: 447-447

    • DOI

      10.3389/fchem.2020.00447

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-16H06444
  • [Journal Article] Macrocyclic Peptide-Mediated Blockade of the CD47-SIRPα Interaction as a Potential Cancer Immunotherapy2020

    • Author(s)
      Hazama Daisuke、Yin Yizhen、Murata Yoji、Matsuda Makoto、Okamoto Takeshi、Tanaka Daisuke、Terasaka Naohiro、Zhao Jinxuan、Sakamoto Mariko、Kakuchi Yuka、Saito Yasuyuki、Kotani Takenori、Nishimura Yoshihiro、Nakagawa Atsushi、Suga Hiroaki、Matozaki Takashi
    • Journal Title

      Cell Chemical Biology

      Volume: 27 Issue: 9 Pages: 1181-1191.e7

    • DOI

      10.1016/j.chembiol.2020.06.008

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07385, KAKENHI-PROJECT-20K21547, KAKENHI-PROJECT-20H05618, KAKENHI-PROJECT-18H04032
  • [Journal Article] Ribosomal Elongation of Aminobenzoic Acid Derivatives2020

    • Author(s)
      Katoh Takayuki、Suga Hiroaki
    • Journal Title

      Journal of the American Chemical Society

      Volume: 142 Issue: 39 Pages: 16518-16522

    • DOI

      10.1021/jacs.0c05765

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20H05618, KAKENHI-PROJECT-18H02080, KAKENHI-PLANNED-16H06444
  • [Journal Article] Minimal lactazole scaffold for in vitro thiopeptide bioengineering2020

    • Author(s)
      Vinogradov Alexander A.、Shimomura Morito、Goto Yuki、Ozaki Taro、Asamizu Shumpei、Sugai Yoshinori、Suga Hiroaki、Onaka Hiroyasu
    • Journal Title

      Nature Communications

      Volume: 11 Issue: 1 Pages: 2272-2272

    • DOI

      10.1038/s41467-020-16145-4

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H05618, KAKENHI-PROJECT-18K05385, KAKENHI-PROJECT-19K22243, KAKENHI-PLANNED-16H06444, KAKENHI-PROJECT-20H02866
  • [Journal Article] Introduction to Thiopeptides: Biological Activity, Biosynthesis, and Strategies for Functional Reprogramming2020

    • Author(s)
      Vinogradov Alexander A.、Suga Hiroaki
    • Journal Title

      Cell Chemical Biology

      Volume: 27 Issue: 8 Pages: 1032-1051

    • DOI

      10.1016/j.chembiol.2020.07.003

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20H05618, KAKENHI-PLANNED-16H06444
  • [Journal Article] Design, Synthesis, and Conformation?Activity Study of Unnatural Bridged Bicyclic Depsipeptides as Highly Potent Hypoxia Inducible Factor-1 Inhibitors and Antitumor Agents2020

    • Author(s)
      Koike Kota、Nagano Masanobu、Ebihara Masahiro、Hirayama Tasuku、Tsuji Mieko、Suga Hiroaki、Nagasawa Hideko
    • Journal Title

      Journal of Medicinal Chemistry

      Volume: 63 Issue: 8 Pages: 4022-4046

    • DOI

      10.1021/acs.jmedchem.9b02039

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20H05618
  • [Journal Article] Ribosomal synthesis and de novo discovery of bioactive foldamer peptides containing cyclic β-amino acids2020

    • Author(s)
      Katoh Takayuki、Sengoku Toru、Hirata Kunio、Ogata Kazuhiro、Suga Hiroaki
    • Journal Title

      Nature Chemistry

      Volume: 12 Issue: 11 Pages: 1081-1088

    • DOI

      10.1038/s41557-020-0525-1

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20H05618, KAKENHI-PROJECT-18H02080, KAKENHI-PROJECT-18K19305, KAKENHI-PLANNED-16H06444
  • [Journal Article] Accurate Broadcasting of Substrate Fitness for Lactazole Biosynthetic Pathway from Reactivity-Profiling mRNA Display2020

    • Author(s)
      Vinogradov Alexander A.、Nagai Emiko、Chang Jun Shi、Narumi Kakeru、Onaka Hiroyasu、Goto Yuki、Suga Hiroaki
    • Journal Title

      Journal of the American Chemical Society

      Volume: 142 Issue: 48 Pages: 20329-20334

    • DOI

      10.1021/jacs.0c10374

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20H05618, KAKENHI-PROJECT-19K22243, KAKENHI-PROJECT-20K15407, KAKENHI-PROJECT-20H02866
  • [Journal Article] Development of cyclic peptides with potent in vivo osteogenic activity through RaPID-based affinity maturation2020

    • Author(s)
      Bashiruddin Nasir K.、Hayashi Mikihito、Nagano Masanobu、Wu Yan、Matsunaga Yukiko、Takagi Junichi、Nakashima Tomoki、Suga Hiroaki
    • Journal Title

      Proceedings of the National Academy of Sciences

      Volume: 117 Issue: 49 Pages: 31070-31077

    • DOI

      10.1073/pnas.2012266117

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H05618, KAKENHI-PROJECT-20H00455, KAKENHI-PROJECT-20H00551, KAKENHI-PROJECT-20K20581
  • [Journal Article] Exploring the Post-translational Enzymology of PaaA by mRNA Display2020

    • Author(s)
      Fleming, S. R., Himes, P. M., Ghodge, S. V., Goto, Y., Suga, H., Bowers, A. A.
    • Journal Title

      J Am Chem Soc

      Volume: 142 Issue: 11 Pages: 5024-5028

    • DOI

      10.1021/jacs.0c01576

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-18H04382, KAKENHI-PROJECT-20H05618, KAKENHI-PROJECT-19K22243, KAKENHI-PROJECT-17H04762, KAKENHI-PLANNED-16H06444
  • [Journal Article] Promiscuous Enzymes Cooperate at the Substrate Level En Route to Lactazole A2020

    • Author(s)
      Vinogradov Alexander A.、Shimomura Morito、Kano Naokazu、Goto Yuki、Onaka Hiroyasu、Suga Hiroaki
    • Journal Title

      Journal of the American Chemical Society

      Volume: 142 Issue: 32 Pages: 13886-13897

    • DOI

      10.1021/jacs.0c05541

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20H05618, KAKENHI-PROJECT-19K22243, KAKENHI-PLANNED-16H06444, KAKENHI-PROJECT-20H02866
  • [Journal Article] Discovery of Functional Macrocyclic Peptides by Means of the RaPID System2019

    • Author(s)
      Tsiamantas Christos、Otero-Ramirez Manuel E.、Suga Hiroaki
    • Journal Title

      Methods Mol Biol

      Volume: 2001 Pages: 299-315

    • DOI

      10.1007/978-1-4939-9504-2_14

    • ISBN
      9781493995035, 9781493995042
    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-16H06444
  • [Journal Article] In Vitro Biosynthesis of Peptides Containing Exotic Azoline Analogues2019

    • Author(s)
      Goto Yuki、Suga Hiroaki
    • Journal Title

      ChemBioChem

      Volume: 21 Issue: 1-2 Pages: 84-87

    • DOI

      10.1002/cbic.201900521

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-16H06444, KAKENHI-PUBLICLY-18H04382, KAKENHI-PROJECT-19K22243, KAKENHI-PROJECT-17H04762
  • [Journal Article] Flexizyme-Enabled Benchtop Biosynthesis of Thiopeptides.2019

    • Author(s)
      Fleming SR, Bartges TE, Vinogradov AA, Kirkpatrick CL, Goto Y, Suga H, Hicks LM, Bowers AA.
    • Journal Title

      J Am Chem Soc.

      Volume: 141 Issue: 2 Pages: 758-762

    • DOI

      10.1021/jacs.8b11521

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06444, KAKENHI-PROJECT-26220204, KAKENHI-PROJECT-17H04762, KAKENHI-PUBLICLY-18H04382
  • [Journal Article] Ribosomal Formation of Thioamide Bonds in Polypeptide Synthesis2019

    • Author(s)
      Maini Rumit、Kimura Hiroyuki、Takatsuji Ryo、Katoh Takayuki、Goto Yuki、Suga Hiroaki
    • Journal Title

      Journal of the American Chemical Society

      Volume: 141 Issue: 51 Pages: 20004-20008

    • DOI

      10.1021/jacs.9b11097

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-16H06444, KAKENHI-PUBLICLY-18H04382, KAKENHI-PROJECT-19K22243, KAKENHI-PROJECT-17H04762
  • [Journal Article] De Novo Carborane-Containing Macrocyclic Peptides Targeting Human Epidermal Growth Factor Receptor2019

    • Author(s)
      Yin Yizhen、Ochi Nobuaki、Craven Timothy W.、Baker David、Takigawa Nagio、Suga Hiroaki
    • Journal Title

      Journal of the American Chemical Society

      Volume: 141 Issue: 49 Pages: 19193-19197

    • DOI

      10.1021/jacs.9b09106

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06444
  • [Journal Article] RiPP生合成経路の改変による人工ペプチド生産2019

    • Author(s)
      後藤 佑樹、井上 澄香、菅 裕明
    • Journal Title

      Farumashia

      Volume: 55 Issue: 7 Pages: 662-667

    • DOI

      10.14894/faruawpsj.55.7_662

    • NAID

      130007671606

    • ISSN
      0014-8601, 2189-7026
    • Language
      Japanese
    • Data Source
      KAKENHI-PLANNED-16H06444, KAKENHI-PUBLICLY-18H04382, KAKENHI-PROJECT-19K22243, KAKENHI-PROJECT-17H04762
  • [Journal Article] Flexizyme-catalyzed synthesis of 3'-aminoacyl-NH-tRNAs.2019

    • Author(s)
      Katoh T, Suga H.
    • Journal Title

      Nucleic Acids Res.

      Volume: pii Issue: 9 Pages: e54-e54

    • DOI

      10.1093/nar/gkz143

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26220204, KAKENHI-PLANNED-16H06444, KAKENHI-PROJECT-18H02080
  • [Journal Article] Chemical and Ribosomal Synthesis of Topologically Controlled Bicyclic and Tricyclic Peptide Scaffolds Primed by Selenoether Formation.2019

    • Author(s)
      Yin Y, Fei Q, Liu W, Li Z, Suga H, Wu C.
    • Journal Title

      Angew Chem Int Ed Engl.

      Volume: 58 Issue: 15 Pages: 4880-4885

    • DOI

      10.1002/anie.201813827

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26220204, KAKENHI-PROJECT-16F16412
  • [Journal Article] Macrocyclic Peptides as Drug Candidates: Recent Progress and Remaining Challenges.2019

    • Author(s)
      Vinogradov AA, Yin Y, Suga H.
    • Journal Title

      J Am Chem Soc.

      Volume: 141 Issue: 10 Pages: 4167-4181

    • DOI

      10.1021/jacs.8b13178

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26220204, KAKENHI-PLANNED-16H06444
  • [Journal Article] Ribosomal Synthesis of Backbone-Cyclic Peptides Compatible with In Vitro Display.2019

    • Author(s)
      Takatsuji R, Shinbara K, Katoh T, Goto Y, Passioura T, Yajima R, Komatsu Y, Suga H.
    • Journal Title

      J Am Chem Soc.

      Volume: 141 Issue: 6 Pages: 2279-2287

    • DOI

      10.1021/jacs.8b05327

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06444, KAKENHI-PROJECT-26220204, KAKENHI-PROJECT-17H04762, KAKENHI-PUBLICLY-18H04382
  • [Journal Article] A Case Study on the Keap1 Interaction with Peptide Sequence Epitopes Selected by the Peptidomic mRNA Display2019

    • Author(s)
      Hirose Hisaaki、Hideshima Tomoki、Katoh Takayuki、Suga Hiroaki
    • Journal Title

      ChemBioChem

      Volume: 20 Issue: 16 Pages: 2089-2100

    • DOI

      10.1002/cbic.201900039

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06444
  • [Journal Article] Optimizing aromatic oligoamide foldamer side-chains for ribosomal translation initiation2019

    • Author(s)
      Tsiamantas Christos、Kwon Sunbum、Douat C?line、Huc Ivan、Suga Hiroaki
    • Journal Title

      Chemical Communications

      Volume: 55 Issue: 51 Pages: 7366-7369

    • DOI

      10.1039/c9cc03547h

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06444
  • [Journal Article] De Novo Discovery of Nonstandard Macrocyclic Peptides as Noncompetitive Inhibitors of the Zika Virus NS2B-NS3 Protease.2019

    • Author(s)
      Nitsche C, Passioura T, Varava P, Mahawaththa MC, Leuthold MM, Klein CD, Suga H, Otting G.
    • Journal Title

      ACS Med Chem Lett.

      Volume: 10 Issue: 2 Pages: 168-174

    • DOI

      10.1021/acsmedchemlett.8b00535

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26220204
  • [Journal Article] Max‐Bergmann award lecture:A RaPID way to discover bioactive nonstandard peptides assisted by the flexizyme and FIT systems2018

    • Author(s)
      Suga H
    • Journal Title

      Journal of Peptide Science

      Volume: 24 Issue: 1

    • DOI

      10.1002/psc.3055

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26220204
  • [Journal Article] Quality control by trans-editing factor prevents global mistranslation of non-protein amino acid α-aminobutyrate.2018

    • Author(s)
      Bacusmo JM, Kuzmishin AB, Cantara WA, Goto Y, Suga H, Musier-Forsyth K.
    • Journal Title

      RNA Biol.

      Volume: 15 Issue: 4-5 Pages: 576-585

    • DOI

      10.1080/15476286.2017.1353846

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26220204, KAKENHI-PLANNED-16H06444, KAKENHI-PROJECT-15K12739, KAKENHI-PUBLICLY-16H01131, KAKENHI-PROJECT-17H04762
  • [Journal Article] RNA Display Methods for the Discovery of Bioactive Macrocycles.2018

    • Author(s)
      Huang Y, Wiedmann MM, Suga H.
    • Journal Title

      Chem Rev.

      Volume: XX Issue: 17 Pages: 10360-10391

    • DOI

      10.1021/acs.chemrev.8b00430

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26220204, KAKENHI-PROJECT-16F16810
  • [Journal Article] Facile Synthesis of Dimeric Thioether-Macrocyclic Peptides with Antibody-like Affinity against Plexin-B12018

    • Author(s)
      Bashiruddin Nasir K.、Matsunaga Yukiko、Nagano Masanobu、Takagi Junichi、Suga Hiroaki
    • Journal Title

      Bioconjugate Chemistry

      Volume: 29 Issue: 6 Pages: 1847-1851

    • DOI

      10.1021/acs.bioconjchem.8b00219

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19298, KAKENHI-PROJECT-26220204, KAKENHI-PROJECT-17H01420
  • [Journal Article] Engineering of RiPP pathways for the production of artificial peptides bearing various non-proteinogenic structures2018

    • Author(s)
      Goto Yuki、Suga Hiroaki
    • Journal Title

      Current Opinion in Chemical Biology

      Volume: 46 Pages: 82-90

    • DOI

      10.1016/j.cbpa.2018.06.014

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06444, KAKENHI-PROJECT-26220204, KAKENHI-PROJECT-17H04762, KAKENHI-PUBLICLY-18H04382
  • [Journal Article] Structure-activity studies of a macrocyclic peptide inhibitor of histone lysine demethylase 4A.2018

    • Author(s)
      Passioura T, Bhushan B, Tumber A, Kawamura A, Suga H.
    • Journal Title

      Bioorg Med Chem.

      Volume: 26 Issue: 6 Pages: 1225-1231

    • DOI

      10.1016/j.bmc.2018.01.013

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06444, KAKENHI-PROJECT-26220204
  • [Journal Article] tRNA engineering for manipulating genetic code.2018

    • Author(s)
      Katoh T, Iwane Y, Suga H.
    • Journal Title

      RNA Biol.

      Volume: 15 Pages: 453-460

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26220204
  • [Journal Article] In vitro expression of genetically encoded non-standard peptides consisting of exotic amino acid building blocks.2018

    • Author(s)
      Hirose H, Tsiamantas C, Katoh T, Suga H.
    • Journal Title

      Curr Opin Biotechnol. 2018 Nov 16;58:

      Volume: 58 Pages: 28-36

    • DOI

      10.1016/j.copbio.2018.10.012

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26220204, KAKENHI-PROJECT-18H02080, KAKENHI-PROJECT-18F18727
  • [Journal Article] Ribosomal Incorporation of Consecutive beta-Amino Acids.2018

    • Author(s)
      Katoh T, Suga H.
    • Journal Title

      J Am Chem Soc.

      Volume: 140 Issue: 38 Pages: 12159-12167

    • DOI

      10.1021/jacs.8b07247

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26220204, KAKENHI-PROJECT-18H02080
  • [Journal Article] Cellular signaling and gene expression profiles evoked by a bivalent macrocyclic peptide that serves as an artificial MET receptor agonist2018

    • Author(s)
      Miao Wenyu、Sakai Katsuya、Ozawa Naoya、Nishiuchi Takumi、Suzuki Yoshinori、Ito Kenichiro、Morioka Tomomi、Umitsu Masataka、Takagi Junichi、Suga Hiroaki、Matsumoto Kunio
    • Journal Title

      Scientific Reports

      Volume: 8 Issue: 1 Pages: 16492-16492

    • DOI

      10.1038/s41598-018-34835-4

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19298, KAKENHI-PROJECT-26220204, KAKENHI-PROJECT-17H01420, KAKENHI-PROJECT-16K08544, KAKENHI-PROJECT-16J05654
  • [Journal Article] Non-competitive cyclic peptides for targeting enzyme?substrate complexes2018

    • Author(s)
      McAllister T. E.、Yeh T.-L.、Abboud M. I.、Leung I. K. H.、Hookway E. S.、King O. N. F.、Bhushan B.、Williams S. T.、Hopkinson R. J.、M?nzel M.、Loik N. D.、Chowdhury R.、Oppermann U.、Claridge T. D. W.、Goto Y.、Suga H.、Schofield C. J.、Kawamura A.
    • Journal Title

      Chemical Science

      Volume: 9 Issue: 20 Pages: 4569-4578

    • DOI

      10.1039/c8sc00286j

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06444, KAKENHI-PROJECT-26220204, KAKENHI-PROJECT-17H04762, KAKENHI-PUBLICLY-18H04382
  • [Journal Article] Artificial <i>In Vitro</i> Biosynthesis Systems for the Development of Pseudo-Natural Products2018

    • Author(s)
      Goto Yuki、Suga Hiroaki
    • Journal Title

      Bull. Chem. Soc. Jpn.

      Volume: 91 Issue: 3 Pages: 410-419

    • DOI

      10.1246/bcsj.20170379

    • NAID

      130006507065

    • ISSN
      0009-2673, 1348-0634
    • Language
      English
    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06444, KAKENHI-PROJECT-26220204, KAKENHI-PROJECT-17H04762, KAKENHI-PUBLICLY-16H01131, KAKENHI-PUBLICLY-18H04382
  • [Journal Article] Display Selection of Exotic Macrocyclic Peptides Expressed under a Radically Reprogrammed 23 Amino Acid Genetic Code.2018

    • Author(s)
      Passioura T, Liu W, Dunkelmann D, Higuchi T, Suga H.
    • Journal Title

      J Am Chem Soc.

      Volume: 140 Issue: 37 Pages: 11551-11555

    • DOI

      10.1021/jacs.8b03367

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26220204
  • [Journal Article] Thioether Macrocyclic Peptides Selected against TET1 Compact Catalytic Domain Inhibit TET1 Catalytic Activity2018

    • Author(s)
      Nishio Kosuke、Belle Roman、Katoh Takayuki、Kawamura Akane、Sengoku Toru、Hanada Kazuharu、Ohsawa Noboru、Shirouzu Mikako、Yokoyama Shigeyuki、Suga Hiroaki
    • Journal Title

      ChemBioChem

      Volume: 19 Issue: 9 Pages: 979-985

    • DOI

      10.1002/cbic.201800047

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19305, KAKENHI-PROJECT-26220204, KAKENHI-PROJECT-16H03293
  • [Journal Article] De Novo Macrocyclic Peptide Inhibitors of Hepatitis B Virus Cellular Entry.2018

    • Author(s)
      Passioura T, Watashi K, Fukano K, Shimura S, Saso W, Morishita R, Ogasawara Y, Tanaka Y, Mizokami M, Sureau C, Suga H, Wakita T.
    • Journal Title

      Cell Chem Biol.

      Volume: 25 Issue: 7 Pages: 906-915

    • DOI

      10.1016/j.chembiol.2018.04.011

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26220204, KAKENHI-PROJECT-26460565, KAKENHI-PROJECT-17H04085
  • [Journal Article] Nonproteinogenic deep mutational scanning of linear and cyclic peptides.2018

    • Author(s)
      Rogers JM, Passioura T, Suga H.
    • Journal Title

      Proc Natl Acad Sci U S A.

      Volume: 115 Issue: 43 Pages: 10959-10964

    • DOI

      10.1073/pnas.1809901115

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26220204
  • [Journal Article] Pyrrole-Mediated Peptide Cyclization Identified through Genetically Reprogrammed Peptide Synthesis.2018

    • Author(s)
      Decoene KW, Vannecke W, Passioura T, Suga H, Madder A.
    • Journal Title

      Biomedicines.

      Volume: 6 Issue: 4 Pages: 99-99

    • DOI

      10.3390/biomedicines6040099

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26220204
  • [Journal Article] Structural Features and Binding Modes of Thioether-Cyclized Peptide Ligands.2018

    • Author(s)
      Otero-Ramirez ME, Passioura T, Suga H.
    • Journal Title

      Biomedicines.

      Volume: 6 Issue: 4 Pages: 116-116

    • DOI

      10.3390/biomedicines6040116

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26220204
  • [Journal Article] Genetic code expansion via integration of redundant amino acid assignment by finely tuning tRNA pools.2018

    • Author(s)
      Tajima K, Katoh T, Suga H.
    • Journal Title

      Curr Opin Chem Biol.

      Volume: 46 Pages: 212-218

    • DOI

      10.1016/j.cbpa.2018.07.010

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26220204
  • [Journal Article] Ribosomal synthesis and folding of peptide-helical aromatic foldamer hybrids.2018

    • Author(s)
      Rogers JM, Kwon S, Dawson SJ, Mandal PK, Suga H, Huc I.
    • Journal Title

      Nat Chem.

      Volume: 10 Issue: 4 Pages: 405-412

    • DOI

      10.1038/s41557-018-0007-x

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06444, KAKENHI-PROJECT-26220204
  • [Journal Article] Crystallographic Analysis of MATE-Type Multidrug Exporter with Its Inhibitors.2018

    • Author(s)
      Kusakizako T, Tanaka Y, Hipolito CJ, Suga H, Nureki O.
    • Journal Title

      Methods Mol Biol.

      Volume: 1700 Pages: 37-57

    • DOI

      10.1007/978-1-4939-7454-2_3

    • ISBN
      9781493974528, 9781493974542
    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26220204, KAKENHI-PROJECT-16H06294
  • [Journal Article] MET Activation by a Macrocyclic Peptide Agonist that Couples to Biological Responses Differently from HGF in a Context-Dependent Manner.2018

    • Author(s)
      Miao W, Sakai K, Imamura R, Ito K, Suga H, Sakuma T, Yamamoto T, Matsumoto K.
    • Journal Title

      Int J Mol Sci.

      Volume: 19 Issue: 10 Pages: 3141-3141

    • DOI

      10.3390/ijms19103141

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26220204, KAKENHI-PROJECT-16K08544
  • [Journal Article] Artificial Division of Codon Boxes for Expansion of the Amino Acid Repertoire of Ribosomal Polypeptide Synthesis.2018

    • Author(s)
      Iwane Y, Katoh T, Goto Y, Suga H.
    • Journal Title

      Methods Mol Biol.

      Volume: 1728 Pages: 17-47

    • DOI

      10.1007/978-1-4939-7574-7_2

    • ISBN
      9781493975730, 9781493975747
    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06444, KAKENHI-PROJECT-26220204, KAKENHI-PROJECT-15K12739, KAKENHI-PUBLICLY-16H01131, KAKENHI-PROJECT-17H04762
  • [Journal Article] Macrocyclic peptide inhibitors for the protein-protein interaction of Zaire Ebola virus protein 24 and karyopherin alpha 5.2017

    • Author(s)
      Song X, Lu LY, Passioura T, Suga H.
    • Journal Title

      Org Biomol Chem.

      Volume: 15 Issue: 24 Pages: 5155-5160

    • DOI

      10.1039/c7ob00012j

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06444, KAKENHI-PROJECT-26220204
  • [Journal Article] Strategies for transitioning macrocyclic peptides to cell-permeable drug leads Journal: Current Opinion in Biotechnology2017

    • Author(s)
      L.J. Walport, R. Obexer, H. Suga
    • Journal Title

      Current Opinion in Chemical Biology

      Volume: 48 Pages: 242-250

    • DOI

      10.1016/j.copbio.2017.07.007

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15F15333, KAKENHI-PROJECT-26220204
  • [Journal Article] Macrocycle peptides delineate locked-open inhibition mechanism for microorganism phosphoglycerate mutases.2017

    • Author(s)
      Yu H, Dranchak P, Li Z, MacArthur R, Munson MS, Mehzabeen N, Baird NJ, Battalie KP, Ross D, Lovell S, Carlow CK, Suga H, Inglese J.
    • Journal Title

      Nat Commun.

      Volume: 8 Issue: 1 Pages: 14932-14932

    • DOI

      10.1038/ncomms14932

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06444
  • [Journal Article] Conformational and chemical selection by a trans-acting editing domain.2017

    • Author(s)
      Danhart EM, Bakhtina M, Cantara WA, Kuzmishin AB, Ma X, Sanford BL, Vargas-Rodriguez O, Ko; M, Goto Y, Suga H, Nakanishi K, Micura R, Foster MP, Musier-Forsyth K.
    • Journal Title

      Proc Natl Acad Sci U S A

      Volume: 114 Issue: 33

    • DOI

      10.1073/pnas.1703925114

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06444, KAKENHI-PROJECT-15K12739, KAKENHI-PUBLICLY-16H01131, KAKENHI-PROJECT-17H04762
  • [Journal Article] tRNA engineering for manipulating genetic code2017

    • Author(s)
      Katoh Takayuki、Iwane Yoshihiko、Suga Hiroaki
    • Journal Title

      RNA Biol.

      Volume: 0 Issue: 4-5 Pages: 1-8

    • DOI

      10.1080/15476286.2017.1343227

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26220204
  • [Journal Article] Effects of an autoinducer analogue on antibiotic tolerance in Pseudomonas aeruginosa.2017

    • Author(s)
      T. Amoh, K. Murakami, R. Kariyama, K. Hori, D. Viducic, K. Hirota, J. Igarashi, H. Suga, H. Kumon, Y. Miyake
    • Journal Title

      J Antimicrob Chemother

      Volume: 印刷中

    • DOI

      10.1093/jac/dkx132

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25461512
  • [Journal Article] Exploring sequence space: harnessing chemical and biological diversity towards new peptide leads2017

    • Author(s)
      R. Obexer, L.J. Walport, H. Suga
    • Journal Title

      Current Opinion in Chemical Biology

      Volume: 38 Pages: 52-61

    • DOI

      10.1016/j.cbpa.2017.02.020

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15F15333, KAKENHI-PROJECT-26220204
  • [Journal Article] Dissection of goadsporin biosynthesis by in vitro reconstitution leading to designer analogues expressed in vivo2017

    • Author(s)
      Ozaki, T., Yamashita, K., Goto, Y., Shimomura, M., Hayashi, S., Asamizu, S., Sugai, Y., Ikeda, H., Suga, H., Onaka, H.
    • Journal Title

      Nat. Commun.

      Volume: 8 Issue: 1 Pages: 14207-14207

    • DOI

      10.1038/ncomms14207

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06447, KAKENHI-PLANNED-16H06444
  • [Journal Article] Logical engineering of D-arm and T-stem of tRNA that enhances d-amino acid incorporation.2017

    • Author(s)
      Katoh T, Iwane Y, Suga H.
    • Journal Title

      Nucleic Acids Res.

      Volume: 45 Issue: 22 Pages: 12601-12610

    • DOI

      10.1093/nar/gkx1129

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06444, KAKENHI-PROJECT-26220204
  • [Journal Article] Highly selective inhibition of histone demethylases by de novo macrocyclic peptides.2017

    • Author(s)
      Kawamura A, Mnzel M, Kojima T, Yapp C, Bhushan B, Goto Y, Tumber A, Katoh T, King ON, Passioura T, Walport LJ, Hatch SB, Madden S, Muller S, Brennan PE, Chowdhury R, Hopkinson RJ, Suga H, Schofield CJ.
    • Journal Title

      Nat Commun

      Volume: 8 Issue: 1 Pages: 14773-14773

    • DOI

      10.1038/ncomms14773

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06444, KAKENHI-PROJECT-15K12739, KAKENHI-PUBLICLY-16H01131, KAKENHI-PROJECT-17H04762
  • [Journal Article] Linker-free incorporation of carbohydrates into in vitro displayed macrocyclic peptides.2017

    • Author(s)
      Jongkees SAK, Umemoto S, Suga H
    • Journal Title

      Chem Sci.

      Volume: 8 Issue: 2 Pages: 1474-1481

    • DOI

      10.1039/c6sc04381j

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06444
  • [Journal Article] A RaPID way to discover nonstandard macrocyclic peptide modulators of drug targets.2017

    • Author(s)
      Passioura T and Suga H
    • Journal Title

      Chem Commun (Camb)

      Volume: 53 Issue: 12 Pages: 1931-1940

    • DOI

      10.1039/c6cc06951g

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K16558, KAKENHI-PROJECT-26220204
  • [Journal Article] Rapid Discovery of Potent and Selective Glycosidase-Inhibiting De Novo Peptides2017

    • Author(s)
      Jongkees Seino A.K.、Caner Sami、Tysoe Christina、Brayer Gary D.、Withers Stephen G.、Suga Hiroaki
    • Journal Title

      Cell Chem Biol.

      Volume: 24 Issue: 3 Pages: 381-390

    • DOI

      10.1016/j.chembiol.2017.02.001

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26220204
  • [Journal Article] A <i>Pseudomonas aeruginosa</i> Quorum-Sensing autoinducer analog enhances the activity of antibiotics against resistant strains2017

    • Author(s)
      T. Amoh, K. Murakami, R. Kariyama, K. Hori, D. Viducic, K. Hirota, J. Igarashi, H. Suga, H. Kumon, Y. Miyake
    • Journal Title

      J. Med. Invest.

      Volume: 64 Issue: 1.2 Pages: 101-109

    • DOI

      10.2152/jmi.64.101

    • NAID

      130005501959

    • ISSN
      1343-1420, 1349-6867
    • Language
      English
    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25461512
  • [Journal Article] Efficient siRNA Delivery by Lipid Nanoparticles Modified with a Nonstandard Macrocyclic Peptide for EpCAM-Targeting.2017

    • Author(s)
      Sakurai Y, Mizumura W, Murata M, Hada T, Yamamoto S, Ito K, Iwasaki K, Katoh T, Goto Y, Takagi A, Kohara M, Suga H, Harashima H.
    • Journal Title

      Mol Pharm

      Volume: 14 Issue: 10 Pages: 3290-3298

    • DOI

      10.1021/acs.molpharmaceut.7b00362

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06444, KAKENHI-PROJECT-15K12739, KAKENHI-PUBLICLY-16H01131, KAKENHI-PROJECT-17H04762
  • [Journal Article] Rapid Discovery of Potent and Selective Glycosidase-Inhibiting De Novo Peptides.2017

    • Author(s)
      Jongkees SAK, Caner S, Tysoe C, Brayer GD, Withers SG, Suga H.
    • Journal Title

      Cell Chem Biol.

      Volume: 16 Pages: 381-390

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06444
  • [Journal Article] Consecutive Elongation of D-Amino Acids in Translation.2017

    • Author(s)
      Katoh T, Tajima K, Suga H.
    • Journal Title

      Cell Chem Biol

      Volume: 24 Issue: 1 Pages: 46-54

    • DOI

      10.1016/j.chembiol.2016.11.012

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06444, KAKENHI-PROJECT-26220204
  • [Journal Article] In vitro biosynthesis systems for elaboration of novel bioacitive peptides2016

    • Author(s)
      Goto Y, Suga H.
    • Journal Title

      Peptide Science

      Volume: 53 Pages: 1-2

    • Data Source
      KAKENHI-PLANNED-16H06444
  • [Journal Article] Haem-dependent dimerization of PGRMC1/Sigma-2 receptor facilitates cancer proliferation and chemoresistance.2016

    • Author(s)
      Kabe Y, Nakane T, Koike I, Yamamoto T, Sugiura Y, Harada E, Sugase K, Shimamura T, Ohmura M, Muraoka K, Yamamoto A, Uchida T, Iwata S, Yamaguchi Y, Krayukhina E, Noda M, Handa H, Ishimori K, Uchiyama S, Kobayashi T, Suematsu M.
    • Journal Title

      Nature Communications

      Volume: 7 Issue: 1 Pages: 11030-11030

    • DOI

      10.1038/ncomms11030

    • NAID

      130007529314

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K07011, KAKENHI-PLANNED-23102002, KAKENHI-ORGANIZER-24118001, KAKENHI-PLANNED-24118002, KAKENHI-PUBLICLY-26102725, KAKENHI-PROJECT-15H04338, KAKENHI-PROJECT-16H06145
  • [Journal Article] tRid, an enabling method to isolate previously inaccessible small RNA fractions.2016

    • Author(s)
      Kazuki Futai, Naohiro Terasaka, Takayuki Katoh, Hiroaki Suga.
    • Journal Title

      Methods

      Volume: 106 Pages: 105-111

    • DOI

      10.1016/j.ymeth.2016.04.033

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26560429, KAKENHI-PROJECT-26220204
  • [Journal Article] Ribosome-mediated synthesis of natural product-like peptides via cell-free translation2016

    • Author(s)
      Rumit Maini
    • Journal Title

      Current Opinion in Chemical Biology

      Volume: 34 Pages: 44-52

    • DOI

      10.1016/j.cbpa.2016.06.006

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16F16033, KAKENHI-PROJECT-26220204
  • [Journal Article] Membrane protein structure determination by SAD, SIR, or SIRAS phasing in serial femtosecond crystallography using an iododetergent2016

    • Author(s)
      Takanori Nakane, Shinya Hanashima, Mamoru Suzuki, Haruka Saiki, Taichi Hayashi, Keisuke Kakinouchi, Shigeru Sugiyama, Satoshi Kawatake, Shigeru Matsuoka, Nobuaki Matsumori, et al
    • Journal Title

      Proceedings of the National Academy of Sciences

      Volume: 113 Issue: 46 Pages: 13039-13044

    • DOI

      10.1073/pnas.1602531113

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-16H00773, KAKENHI-PROJECT-15H03121, KAKENHI-PROJECT-15H04338, KAKENHI-PROJECT-26440028, KAKENHI-PROJECT-26840021, KAKENHI-PROJECT-15K18487
  • [Journal Article] Essential structural elements in tRNAPro for EF-P-mediated alleviation of translation stalling2016

    • Author(s)
      Katoh Takayuki、Wohlgemuth Ingo、Nagano Masanobu、Rodnina Marina V.、Suga Hiroaki
    • Journal Title

      Nature Communications

      Volume: 7 Issue: 1 Pages: 11657-11657

    • DOI

      10.1038/ncomms11657

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26220204
  • [Journal Article] Expanding the amino acid repertoire of ribosomal polypeptide synthesis via the artificial division of codon boxes2016

    • Author(s)
      Yoshihiko Iwane, Azusa Hitomi, Hiroshi Murakami, Takayuki Katoh, Yuki Goto, and Hiroaki Suga
    • Journal Title

      Nature Chemistry

      Volume: 8 Issue: 4 Pages: 317-325

    • DOI

      10.1038/nchem.2446

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-14J09576, KAKENHI-PROJECT-26220204
  • [Journal Article] A human microRNA precursor binding to folic acid discovered by small RNA transcriptomic SELEX.2016

    • Author(s)
      Naohiro Terasaka, Kazuki Futai, Takayuki Katoh, Hiroaki Suga.
    • Journal Title

      RNA

      Volume: 22 Issue: 12 Pages: 1918-1928

    • DOI

      10.1261/rna.057737.116

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26560429, KAKENHI-PROJECT-26220204
  • [Journal Article] A Post-translational Cyclodehydratase, PatD, Tolerates Sequence Variation in the C-terminal Region of Substrate Peptides2016

    • Author(s)
      Y. Goto, H. Suga
    • Journal Title

      Chem. Lett.

      Volume: 45 Issue: 11 Pages: 1247-1249

    • DOI

      10.1246/cl.160562

    • NAID

      130005509442

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-16H01131, KAKENHI-PLANNED-16H06444
  • [Journal Article] A three dimensional movie of structural changes in bacteriorhodopsin.2016

    • Author(s)
      Nango, E., Royant, A.†, Kubo, M.† et al. (†equal contribution)(45名中2番目)
    • Journal Title

      Science

      Volume: 354 Issue: 6319 Pages: 1552-1557

    • DOI

      10.1126/science.aah3497

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-15H01055, KAKENHI-PROJECT-15H03841, KAKENHI-PROJECT-15H04338, KAKENHI-PROJECT-15H05476, KAKENHI-PROJECT-15K18486, KAKENHI-PROJECT-15K18523, KAKENHI-PROJECT-16H06315
  • [Journal Article] "Model foldamers: applications and structures of stable macrocyclic peptides identified using in vitro selection."2015

    • Author(s)
      Jongkees, S. A. K.; Hipolito, C. J.; Rogers, J. M.; Suga, H.
    • Journal Title

      New Journal of Chemistry

      Volume: unknown Issue: 5 Pages: 3197-3207

    • DOI

      10.1039/c4nj01633e

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-13F03766
  • [Journal Article] Recent Developments of Engineered Translational Machineries for the Incorporation of Non-Canonical Amino Acids into Polypeptides2015

    • Author(s)
      Naohiro Terasaka, Yoshihiko Iwane, Anna-Skrollan Geiermann, Yuki Goto & Hiroaki Suga
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 16 Issue: 3 Pages: 6513-6531

    • DOI

      10.3390/ijms16036513

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-12J08188, KAKENHI-PROJECT-14J09576, KAKENHI-PROJECT-26220204
  • [Journal Article] Selection-based discovery of macrocyclic peptides for the next generation therapeutics2015

    • Author(s)
      T. Morita N.D. Loik C.J. Hipolito Y. Goto H. Suga
    • Journal Title

      Current Opinion in Chemical Biology

      Volume: 26 Pages: 34-41

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-14F04065
  • [Journal Article] Model foldamers: applications and structures of stable macrocyclic peptides identified using in vitro selection2015

    • Author(s)
      Seino A. K. Jongkees, Christopher J. Hipolito, Joseph M. Rogers, Hiroaki Suga
    • Journal Title

      New Journal of Chemistry

      Volume: unknown

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-13F03026
  • [Journal Article] Synthesis of fused tricyclic peptides using a reprogrammed translation system and chemical modification.2015

    • Author(s)
      N.K. Bashiruddin; M. Nagano; H. Suga
    • Journal Title

      Bioorganic chemistry

      Volume: 61 Pages: 45-50

    • DOI

      10.1016/j.bioorg.2015.06.002

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26220204, KAKENHI-PROJECT-13J03534
  • [Journal Article] Selection-based discovery of macrocyclic peptides for the next generation therapeutics.2015

    • Author(s)
      T. Morioka; N.D. Loik; C.J. Hipolito; Y. Goto; H. Suga
    • Journal Title

      Current opinion in chemical biology

      Volume: 26C Pages: 34-41

    • DOI

      10.1016/j.cbpa.2015.01.023

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26220204, KAKENHI-PROJECT-15H06073
  • [Journal Article] Diverse application platform for hard X-ray diffraction in SACLA (DAPHNIS): application to serial protein crystallography using an X-ray free-electron laser.2015

    • Author(s)
      Tono K, Shimamura T, et al.
    • Journal Title

      J. Synchrotron Rad.

      Volume: 22 Issue: 3 Pages: 532-537

    • DOI

      10.1107/s1600577515004464

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24370044, KAKENHI-PROJECT-25650023, KAKENHI-PUBLICLY-26102725, KAKENHI-PROJECT-26440028, KAKENHI-PROJECT-15H04338
  • [Journal Article] A fluorescent imaging probe based on a macrocyclic scaffold that binds to cellular EpCAM2015

    • Author(s)
      Iwasaki, K. Goto, Y. Katoh, T. Yamashita, T. Kaneko, S. Suga, H.
    • Journal Title

      J Mol Evol

      Volume: 81 Issue: 5-6 Pages: 210-217

    • DOI

      10.1007/s00239-015-9710-z

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K12739, KAKENHI-PROJECT-26220204
  • [Journal Article] Recent developments of engineered translational machineries for the incorporation of non-canonical amino acids into polypeptides2015

    • Author(s)
      Naohiro Terasaka, Yoshihiko Iwane, Anna-Skrollan Geiermann, Yuki Goto and Hiroaki Suga,
    • Journal Title

      Int. J. Mol. Sci.

      Volume: 16(3) Pages: 6513-6531

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-13F03730
  • [Journal Article] Artificial human Met agonists based on macrocycle scaffolds2015

    • Author(s)
      Ito K, Sakai K, Suzuki Y, Ozawa N, Hatta T, Natsume T, Matsumoto K, Suga H.
    • Journal Title

      Nature Communications

      Volume: 6 Issue: 1 Pages: 6373-6373

    • DOI

      10.1038/ncomms7373

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-ORGANIZER-24115001, KAKENHI-PLANNED-24115007, KAKENHI-PROJECT-24300329, KAKENHI-PROJECT-15K14473, KAKENHI-PROJECT-26220204
  • [Journal Article] Native sulfur/chlorine SAD phasing for serial femtosecond crystallography.2015

    • Author(s)
      Nakane T, Song C, Suzuki M, Nango E, Kobayashi J, Masuda T, Inoue S, Mizohata E, Nakatsu T, Tanaka T, Tanaka R, Shimamura T, Tono K, Joti Y, Kameshima T, Hatsui T, Yabashi M, Nureki O, Iwata S, Sugahara M.
    • Journal Title

      Acta Crystallogr D Biol Crystallogr.

      Volume: 71 Issue: 12 Pages: 2519-25

    • DOI

      10.1107/s139900471501857x

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26440028, KAKENHI-PUBLICLY-26102725, KAKENHI-PROJECT-15H04338, KAKENHI-PROJECT-25450167, KAKENHI-PROJECT-15K14941, KAKENHI-PROJECT-25650026
  • [Journal Article] Flexizymes-facilitated genetic code reprogramming leading to the discovery of drug-like peptides2014

    • Author(s)
      N. Terasaka, H. Suga
    • Journal Title

      Chemistry Letters

      Volume: 43 Pages: 11-19

    • NAID

      130004427082

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Journal Article] Reprogramming the genetic code in vitro2014

    • Author(s)
      T. Passioura; H. Suga
    • Journal Title

      Trends in Biochemical Sciences

      Volume: 39 Issue: 9 Pages: 400-408

    • DOI

      10.1016/j.tibs.2014.07.005

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26220204
  • [Journal Article] Selection-based discovery of druglike macrocyclic peptides2014

    • Author(s)
      T. Passioura, T. Katoh, Y. Goto, H. Suga
    • Journal Title

      Selection-based discovery of druglike macrocyclic peptides

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Journal Article] One-pot synthesis of azoline-containing peptides in a cell-free translation system integrated with a posttranslational cyclodehydratase2014

    • Author(s)
      Y. Goto, Y. Ito, Y. Kato, S. Tsunoda, H. Suga*
    • Journal Title

      Chemistry and Biology

      Volume: (in press)(未確定)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Journal Article] Structural Basis for Potent Inhibition of SIRT2 Deacetylase by a Macrocyclic Peptide Inducing Dynamic Structural Change2014

    • Author(s)
      K. Yamagata, Y. Goto, H. Nishimasu, J. Morimoto, R. Ishitani, N. Dohmae, N. Takeda, R. Nagai, I. Komuro, H. Suga, O. Nureki
    • Journal Title

      Structure

      Volume: 22 Pages: 345-352

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Journal Article] Structural basis for gating mechanisms of a eukaryotic P-glycoprotein homolog2014

    • Author(s)
      A. Kodan, T. Yamaguchi, T. Nakatsu, K. Sakiyama, C.J. Hipolito, A. Fujioka, R. Hirokane, K. Ikeguchi, B. Watanabe,J. Hiratake, Y. Kimura, H. Suga, K. Ueda, H. Kato
    • Journal Title

      Pro. Nat. Acad. Sci

      Volume: 111 Pages: 4049-4054

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Journal Article] Protein cocrystallization molecules originating from in vitro selected macrocyclic peptides2014

    • Author(s)
      C.J. Hipolito, N.K. Bashiruddin, H. Suga
    • Journal Title

      Current Opinion in Structural Biology

      Volume: 26 Pages: 24-31

    • DOI

      10.1016/j.sbi.2014.03.001

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Journal Article] Selection-based discovery of druglike macrocyclic peptides2014

    • Author(s)
      T. Passioura, T. Katoh, Y. Goto, H. Suga
    • Journal Title

      Annual Review in Biochemistry

      Volume: (in press)(未確定)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Journal Article] Construction and screening of vast libraries of natural product-like macrocyclic peptides using in vitro display technologies2014

    • Author(s)
      N.K. Bashiruddin; H. Suga
    • Journal Title

      Current Opinion in Chemical Biology

      Volume: 24C Pages: 131-138

    • DOI

      10.1016/j.cbpa.2014.11.011

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26220204
  • [Journal Article] An orthogonal ribosome-tRNAs pair via the engineering of peptidyl transferase center2014

    • Author(s)
      N. Terasaka, G. Hayashi1, T. Katoh, and H. Suga
    • Journal Title

      Nature Chemical Biology

      Volume: (in press)

    • NAID

      120006348461

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Journal Article] An orthogonal ribosome-tRNAs pair via the engineering of peptidyl transferase center2014

    • Author(s)
      N. Terasaka, G. Hayashil, T. Katoh, and H. Suga
    • Journal Title

      Nature Chemical Biology

      Volume: (in press)(未確定)

    • NAID

      120006348461

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Journal Article] One-pot synthesis of azoline-containing peptides in a cell-free translation system integrated with a posttranslational cyclodehydratase SIRT22014

    • Author(s)
      Y. Goto, Y. Ito, Y. Kato, S. Tsunoda, H. Suga
    • Journal Title

      Chemistry and Biology

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Journal Article] Structural basis for gating mechanisms of a eukaryotic P-glycoprotein homolog2014

    • Author(s)
      A. Kodan, T. Yamaguchi, T. Nakatsu, K. Sakiyama, C. J. Hipolito, A. Fujioka, R. Hirokane, K. Ikeguchi, B. Watanabe, J. Hiratake, Y. Kimura, H. Suga, K. Ueda, H. Kato
    • Journal Title

      Pro. Nat. Acad. Sci.

      Volume: 111(未確定) Pages: 4049-4054

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Journal Article] Technologies for the Synthesis of mRNA-Encoding Libraries and Discovery of Bioactive Natural Product-Inspired Non-Traditional Macrocyclic Peptides2013

    • Author(s)
      Kenichiro Ito, Toby Pass ioura. Hiroaki Suga
    • Journal Title

      Molecules

      Volume: 18 Issue: 3 Pages: 3502-3528

    • DOI

      10.3390/molecules18033502

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-11J07727, KAKENHI-PROJECT-21000005
  • [Journal Article] In Vitro Selection of Multiple Libraries Created by Genetic Code Reprogramming To Discover Macrocyclic Peptides That Antagonize VEGFR2 Activity in Living Cells2013

    • Author(s)
      T. Kawakami, T. Ishizawa, T. Fujino, P.C. Reid, H. Suga, H. Murakami
    • Journal Title

      ACS Chemical Biology

      Volume: 8 Issue: 6 Pages: 1205-1514

    • DOI

      10.1021/cb300697h

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Journal Article] Structural basis for the drug extrusion mechanism by a MATE multidrug transporter2013

    • Author(s)
      Y. Tanaka, C.J. Hipolito, A.D. Maturana, K. Ito, T. Kuroda, T. Higuchi, T. Katoh, H.E. Kato, M. Hattori, K. Kumazaki, T. Tsukazaki, R. Ishitani, H. Suga, O. Nureki
    • Journal Title

      Nature

      Volume: 496 Issue: 21 Pages: 247-251

    • DOI

      10.1002/chem.201300247

    • NAID

      120005716854

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Journal Article] Structural basis for the drug extrusion mechanism by a MATE multidrug transporter2013

    • Author(s)
      Y・ Tanaka, C・J・ Hipolito, A・D・ Maturana, K・ Ito, T・ Kuroda, T・ Higuchi, T・ Katoh, H・E・ Kato, M・ Hattori, K・ Kumazaki, T・ Tsukazaki, R・ Ishitani, H・ Suga, O・ Nureki
    • Journal Title

      Nature

      Volume: 496 Issue: 7444 Pages: 247-51

    • DOI

      10.1038/nature12014

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-11F01344, KAKENHI-PROJECT-11J06643, KAKENHI-PROJECT-21000005, KAKENHI-PLANNED-22117007, KAKENHI-PUBLICLY-24121704, KAKENHI-PROJECT-24227004, KAKENHI-PROJECT-24570150, KAKENHI-PROJECT-24681047, KAKENHI-PROJECT-24687016, KAKENHI-PROJECT-25291011
  • [Journal Article] Non-standard peptide expression under the genetic code consisting of reprogrammed dual sense codons2013

    • Author(s)
      Y. Goto, M. Iseki, A. Hitomi, H. Murakami, and H. Suga
    • Journal Title

      ACS Chemical Biology

      Volume: 8 Issue: 12 Pages: 266-719

    • DOI

      10.1021/cb400549p

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21000005, KAKENHI-PROJECT-24655146
  • [Journal Article] Distinct tRNA recognition strategies used by a homologous family of editing domains prevent mistranslation2013

    • Author(s)
      M. Das, O. Vargas-Rodriguez, Y. Goto, H. Suga, K. Museir-Forsyth
    • Journal Title

      Nucleic Acids Research

      Volume: 未確定 Issue: 6 Pages: 3943-3953

    • DOI

      10.1093/nar/gkt1332

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Journal Article] A macrocyclic peptide that serves as a cocrystallization ligand and inhibits the function of a MATE family transporte2013

    • Author(s)
      C・J・ Hipolito, Y・Tanaka, T・ Katoh, O・ Nureki, H・ Suga
    • Journal Title

      Molecules

      Volume: 18 Issue: 9 Pages: 10514-30

    • DOI

      10.3390/molecules180910514

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-11F01344, KAKENHI-PROJECT-21000005, KAKENHI-PROJECT-24227004, KAKENHI-PROJECT-24681047
  • [Journal Article] Reevaluation of the D-amino acid compatibility with the elongation event in translation2013

    • Author(s)
      T. Fujino, Y. Goto, H. Suga, H. Murakami
    • Journal Title

      Journal of American Chemical Society

      Volume: 135 Issue: 5 Pages: 1830-1837

    • DOI

      10.1021/ja309570x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21000005, KAKENHI-PROJECT-24655146
  • [Journal Article] In Vitro Selection of Anti-Akt2 Thioether-Macrocyclic Peptides Leading to Isoform-Selective Inhibitors2012

    • Author(s)
      Hayashi, Y.; Morimoto, J.: Suga, H.
    • Journal Title

      ACS Chemical Biology

      Volume: 7 Issue: 3 Pages: 607-613

    • DOI

      10.1021/cb200388k

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-09J09079, KAKENHI-PROJECT-21000005
  • [Journal Article] In Vitro Selection of Anti-Akt2 Thioether-Macrocyclic Peptides Leading to Isoform- Selective Inhibitors2012

    • Author(s)
      Y. Hayashi, J. Morimoto, H. Suga*
    • Journal Title

      ACS Chemical Biology

      Volume: 7 Pages: 607-613

    • Data Source
      KAKENHI-PROJECT-21000005
  • [Journal Article] Ribosomal production and in vitro selection of natural product-like peptidomimetics: The FIT and RaPID systems2012

    • Author(s)
      C. J. Hipolito, H. Suga*
    • Journal Title

      Current Opinion in Chemical Biology

      Volume: 16 Pages: 196-203

    • Data Source
      KAKENHI-PROJECT-21000005
  • [Journal Article] Selective thioether macrocyclization of peptides having the N-terminal 2-chloroacetyl group and competing two or three cysteine residues in translation2012

    • Author(s)
      Kazuhiro Iwasaki, Yuki Goto, Takayuki Katoh, Hiroaki Suga
    • Journal Title

      Org.Biomol.Chem.

      Volume: 10 Issue: 30 Pages: 5783-5786

    • DOI

      10.1039/c2ob25306b

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-10J09695, KAKENHI-PROJECT-21000005, KAKENHI-PROJECT-22710210, KAKENHI-PROJECT-22750145, KAKENHI-PROJECT-24655146, KAKENHI-PROJECT-24681047
  • [Journal Article] Discovery of Macrocyclic Peptides Armed with a Mechanism-Based Warhead : Isoform-Selective Inhibition of Human Deacetylase SIRT22012

    • Author(s)
      Morimoto, J.: Hayashi, Y., Suga, H.
    • Journal Title

      Angewandte Chemie International Edition

      Volume: (In press) Issue: 14 Pages: 3423-3427

    • DOI

      10.1002/anie.201108118

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-09J09079, KAKENHI-PROJECT-21000005
  • [Journal Article] Ribosomal synthesis of backbone-macrocyclic peptides containing γ-amino acids2011

    • Author(s)
      Y.Ohshiro, E.Nakajima, Y.Goto, S.Fuse, T.Takahashi, T.Doi, H.Suga
    • Journal Title

      ChemBioChem

      Volume: 12 Issue: 8 Pages: 1183-1187

    • DOI

      10.1002/cbic.201100104

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21000005, KAKENHI-PROJECT-22750145
  • [Journal Article] ペプチド医薬品開発の新基盤技術『RaPIDシステム』2011

    • Author(s)
      下舞大・後藤佑樹・菅裕明
    • Journal Title

      化学工業

      Volume: 62 Pages: 109-115

    • Data Source
      KAKENHI-PROJECT-21000005
  • [Journal Article] Apolar surface area determines the efficiency of translocon-mediated membrane-protein integration into the endoplasmic reticulum2011

    • Author(s)
      K.Ojemalm, T.Higuchi, Y.Jiang, U.Langel, I.Nilsson, S.H.White, H.Suga*, G.von Heijne
    • Journal Title

      Pro.Nat.Acad.Sci.

      Volume: 108(31) Issue: 31

    • DOI

      10.1073/pnas.1100120108

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Journal Article] Flexizymes : Their Evolutionary History and the Origin of Catalytic Function2011

    • Author(s)
      Morimoto, J.; Hayashi, Y.; K.Iwasaki, K.; Suga, H.
    • Journal Title

      Accounts of Chemical Research

      Volume: 44 Issue: 12 Pages: 1359-1368

    • DOI

      10.1021/ar2000953

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-09J09079, KAKENHI-PROJECT-21000005
  • [Journal Article] Natural product-like macrocyclic N-methyl-peptide inhibitors against a ubiquitin ligase uncovered from a ribosome-expressed de novo library2011

    • Author(s)
      Y.Yamagishi, I.Shoji, S.Miyagawa, T.Kawakami, T.Katoh, Y.Goto, H.Suga*
    • Journal Title

      Chemistry & Biology

      Volume: 18 Issue: 12 Pages: 1562-1570

    • DOI

      10.1016/j.chembiol.2011.09.013

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21000005, KAKENHI-PROJECT-22710210, KAKENHI-PROJECT-22750145
  • [Journal Article] Small-molecule inhibitor binding to an N-acyl-homoserine lactone synthase2011

    • Author(s)
      J.Chung, E.Goo, S.Yu, O.Choi, J.Lee, J.Kim, H.Kim, J.Igarashi, H.Suga
    • Journal Title

      Pro.Nat.Acad.Sci.

      Volume: 108(29) Issue: 29 Pages: 12089-12094

    • DOI

      10.1073/pnas.1103165108

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Journal Article] Flexizymes for genetic code reprogramming2011

    • Author(s)
      Y.Goto, T.Katoh, H.Suga
    • Journal Title

      Nature Protocols

      Volume: 6 Issue: 6 Pages: 779-790

    • DOI

      10.1038/nprot.2011.331

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21000005, KAKENHI-PROJECT-22710210, KAKENHI-PROJECT-22750145
  • [Journal Article] Ribosomal synthesis of backbone macrocyclic peptides2011

    • Author(s)
      T.Katoh, Y.Goto, S.Raza, H.Suga*
    • Journal Title

      Chemical Communication

      Volume: 47 Issue: 36 Pages: 9946-9958

    • DOI

      10.1039/c1cc12647d

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21000005, KAKENHI-PROJECT-22710210, KAKENHI-PROJECT-22750145
  • [Journal Article] Synthesis of a backbone-cyclic peptide SFTI-1 promoted by the induced peptidyl-tRNA drop-off2011

    • Author(s)
      T.-J.Kang, Y.Hayashi, H.Suga
    • Journal Title

      Angewandte Chemie International Edition

      Volume: 50 Pages: 2159-2161

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Journal Article] Engineering of the redox ribozyme for the determination of its architechure.2010

    • Author(s)
      S.B.Pattnaik, K.Jin, K.Futai, H.Suga
    • Journal Title

      Chemistry Letters

      Volume: 39 Pages: 786-787

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Journal Article] RaPIDシステムによる特殊ペプチド薬剤の探索2010

    • Author(s)
      飯田健夫・菅裕明
    • Journal Title

      フロンティア22:生命現象を理解する分子ツール

      Pages: 71-76

    • Data Source
      KAKENHI-PROJECT-21000005
  • [Journal Article] RaPIDシステムが拓く新創薬戦略2010

    • Author(s)
      後藤佑樹、伊東利紗、菅裕明
    • Journal Title

      MEDCHEM NEWS

      Volume: 4 Pages: 26-31

    • NAID

      130007944543

    • Data Source
      KAKENHI-PROJECT-21000005
  • [Journal Article] 特殊環状ペプチドの翻訳合成と医薬品探索への展開2010

    • Author(s)
      林剛介・大城幸紀・菅裕明
    • Journal Title

      生化学

      Volume: 6 Pages: 505-514

    • NAID

      10026899979

    • Data Source
      KAKENHI-PROJECT-21000005
  • [Journal Article] 擬天然物特殊ペプチドのプログラム翻訳合成と応用2010

    • Author(s)
      菅裕明・樋口岳
    • Journal Title

      有機合成化学協会誌

      Volume: 68 Pages: 217-227

    • NAID

      10026868150

    • Data Source
      KAKENHI-PROJECT-21000005
  • [Journal Article] Ribosome evolution for two artificial amino acids in E.coli2010

    • Author(s)
      G.Hayashi, Y.Goto, H.Suga
    • Journal Title

      Chemistry&Biology

      Volume: 17 Pages: 320-321

    • Data Source
      KAKENHI-PROJECT-21000005
  • [Journal Article] Ribosomal synthesis of dehydrobutyrineand methyllanthionine-containing peptides2009

    • Author(s)
      Y. Goto, K. Iwasaki, K. Torikai, H. Murakami, H. Suga
    • Journal Title

      Chemical Communication (in press)

    • Data Source
      KAKENHI-PROJECT-16101007
  • [Journal Article] A flexizyme that selectively charges ameno activated with a water-friendly leaving group2009

    • Author(s)
      N. Niwa, Y. Yamagishi, H. Murakami, H. Suga
    • Journal Title

      Bioorganic Medicinal Chemistry Letter (in press掲載確定)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16101007
  • [Journal Article] Bases in the anticodon loop of tRNA(GGC)(Ala)prevent misreading2009

    • Author(s)
      H.Murakami, A.Ohta, H.Suga
    • Journal Title

      Nature Structural & Molecular Biology 16

      Pages: 353-358

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Journal Article] Ribosomal synthesis of dehydrobutyrine- and methyllanthionine-containing peptides2009

    • Author(s)
      Y.Goto, K.Iwasaki, K.Torikai, H.Murakami, H.Suga
    • Journal Title

      Chemical Communication

      Pages: 3419-3421

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Journal Article] Diverse backbone-cyclized peptides via codon reprogramming2009

    • Author(s)
      T.Kawakami, A.Ohta, M.Ohuchi, H.Ashigai, H.Murakami, H.Suga
    • Journal Title

      Nature Chemical Biology 5

      Pages: 888-890

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Journal Article] Translation initiation with initiator tRNA charged with exotic peptides2009

    • Author(s)
      Y. Goto, H. Suga
    • Journal Title

      Journal of American Chemical Society 131

      Pages: 5040-5041

    • Data Source
      KAKENHI-PROJECT-16101007
  • [Journal Article] A flexizyme that selectively charges amino acids activated by a water-ffriendly leaving group2009

    • Author(s)
      N.Niwa, Y.Yamagishi, H.Murakami, H.Suga
    • Journal Title

      Bioorganic Medicinal Chemistry Letter 19

      Pages: 3892-3894

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21241051
  • [Journal Article] Ribosomal synthesis of dehydrobutyrine- and methyllanthionine-containing peptides2009

    • Author(s)
      Y.Goto, K.Iwasaki, K.Torikai, H.Murakami, H.Suga
    • Journal Title

      Chemical Communication

      Pages: 1469-1472

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21241051
  • [Journal Article] Translation initiation with initiator tRNA charged with exotic peptides2009

    • Author(s)
      Y.Goto, H.Suga
    • Journal Title

      Journal of the American Chemical Society 131

      Pages: 5040-5041

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Journal Article] Ribosomal synthesis of cyclic peptides with a fluorogenic oxidative coupling reaction2009

    • Author(s)
      Y.Yamagishi, H.Ashigai, Y.Goto, H.Murakami, H.Suga
    • Journal Title

      ChemBioChem 10

      Pages: 1469-1472

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21241051
  • [Journal Article] Ribosomal synthesis of cyclic peptides with a fluorogenic oxidative coupling reaction2009

    • Author(s)
      Y.Yamagishi, H.Ashigai, Y.Goto, H.Murakami, H.Suga
    • Journal Title

      ChemBioChem 10

      Pages: 1469-1472

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Journal Article] Ribosomal synthesis of peptides with C-terminal lactams, thiolactones, and alkylamides2009

    • Author(s)
      E.Nakajima, Y.Goto, Y.Sako, H.Murakami, H.Suga
    • Journal Title

      ChemBioChem 10

      Pages: 1186-1192

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Journal Article] Ribosomal Synthesis of Peptides with C-Terminal Lactams, Thiolactones, and Alkylamides2009

    • Author(s)
      E. Nakajima, Y. Goto, Y. Sako, H. Murakami and H. Suga
    • Journal Title

      ChemBioChem (in press掲載確定)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16101007
  • [Journal Article] Ribosomal synthesis of dehydrobutyrine-and methyllanthinonine-containing2009

    • Author(s)
      Y. Goto, H. Suga
    • Journal Title

      Chemical Communication (in press掲載確定)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16101007
  • [Journal Article] A flexizyme that selectively charges amino acids activated with awater-friendly leaving group2009

    • Author(s)
      N. Niwa, Y. Yamagishi, H. Murakami, H. Suga
    • Journal Title

      Bioorganic Medicinal Chemistry Letter (in press)

    • Data Source
      KAKENHI-PROJECT-16101007
  • [Journal Article] A flexizyme that selectively charges amino acids activated by a water-friendly leaving group2009

    • Author(s)
      N.Niwa, Y.Yamagishi, H.Murakami, H.Suga
    • Journal Title

      Bioorganic Medicinal Chemistry Letter 19

      Pages: 3892-3894

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Journal Article] Bases in the anticodons loop of tRNA^<Ala> GGC prevent misreading2009

    • Author(s)
      H. Murakami, A. Ohta, H. Suga
    • Journal Title

      Nature Structural & Molecular Biology 16

      Pages: 353-358

    • Data Source
      KAKENHI-PROJECT-16101007
  • [Journal Article] Bases in the anticodons loop of tRNAAlaGGC prevent misreading2009

    • Author(s)
      H. Murakami, A.Ohta, H.Suga
    • Journal Title

      Nature Structural &Molecular Biology 16

      Pages: 353-358

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16101007
  • [Journal Article] Ribosomal synthesis of peptidase-resistant peptides closed by a non-reducible inter-sidechain bond2008

    • Author(s)
      Y. Sako, Y. Goto, H. Murakami, H. Suga
    • Journal Title

      ACS Chemical Biology 3

      Pages: 241-249

    • Data Source
      KAKENHI-PROJECT-16101007
  • [Journal Article] Ribosomal synthesis of peptidase-resistant peptides closed by a non-reducible inter-sidechain bond2008

    • Author(s)
      Y. Sako, Y. Goto, H. Murakami, H. Suga
    • Journal Title

      ACS Chemical Biology 44(in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16101007
  • [Journal Article] Ribosomal synthesis of bicyclic peptides with two orthogomal inter-sidechain2008

    • Author(s)
      Y. Sako, J Morimoto, H. Murakami, H. Suga
    • Journal Title

      Journal of American Chemical Society 130

      Pages: 7932-7934

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16101007
  • [Journal Article] Strcutural basis of specific tRNA aminoacylattion by a small in vitro selected ribozyme2008

    • Author(s)
      H. Xiao, H. Murakami, H. Suga, A. R. Ferre-D'Amare
    • Journal Title

      Nature 454

      Pages: 358-361

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16101007
  • [Journal Article] Exploration of incorporation of Nalpha-methylated amino acids into peptides by sense-suppression method2008

    • Author(s)
      T. Kawakami, H. Murakami, H. Suga
    • Journal Title

      Nucleic Acids Symposium Series 51

      Pages: 361-362

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16101007
  • [Journal Article] Initiating translation with D-amino acids2008

    • Author(s)
      Y. Goto, H. Murakami, H. Suga
    • Journal Title

      RNA 14

      Pages: 1399-1410

    • Data Source
      KAKENHI-PROJECT-16101007
  • [Journal Article] Messenger RNA-directed incorporation of multiple N-methyl-amino acids into linear and cyclic peptides2008

    • Author(s)
      T. Kawakami, H. Murakami, H. Suga
    • Journal Title

      Chemistry & Biology 15

      Pages: 32-42

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16101007
  • [Journal Article] Ribosomal synthesis of bicyclicpeptides with two orthogonalinter-sidechain reactions2008

    • Author(s)
      Y. Sako, J. Morimoto, H. Murakami, H. Suga
    • Journal Title

      Journal of American Chemical Society 130

      Pages: 7932-7934

    • Data Source
      KAKENHI-PROJECT-16101007
  • [Journal Article] Reprogramming the initiation event in translation for the synthesis of physiologically stablecyclic peptides2008

    • Author(s)
      Y. Goto, A. Ohta, Y. Sako, Y. Yamagishi, H. Murakami, H. Suga
    • Journal Title

      ACS Chemical Biology 4

      Pages: 120-129

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16101007
  • [Journal Article] Polymerization of α-hydroxy acids by ribosomes2008

    • Author(s)
      A. Ohta, H. Murakami, H. Suga
    • Journal Title

      ChemBioChem (in press)

    • Data Source
      KAKENHI-PROJECT-16101007
  • [Journal Article] Expression of histone H3 tailswith combinatorial lysinemodifications under thereprogrammed genetic code for theinvestigation on epigenetic markers2008

    • Author(s)
      T.-J. Kang, S. Yuzawa, H. Suga
    • Journal Title

      Chemistry &Biology 15

      Pages: 1166-1174

    • Data Source
      KAKENHI-PROJECT-16101007
  • [Journal Article] Expression of histone H3 tails with combinatorial lysine modifications under the reprogrammed genetic code for the investigation on epigenetic markers2008

    • Author(s)
      T. J. Kang, S. Yuzawa, H. Suga
    • Journal Title

      Chemistry & Bioloty 15

      Pages: 1166-1174

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16101007
  • [Journal Article] Messenger RNA-directed incorporation of multiple N-methyl-amino acids into linear and cyclic peptides2008

    • Author(s)
      T. Kawakami, H. Murakami, H. Suga
    • Journal Title

      Chemistry &Biology 15

      Pages: 32-42

    • Data Source
      KAKENHI-PROJECT-16101007
  • [Journal Article] Polymerization of a-hydroxy acids by ribosomes2008

    • Author(s)
      A. Ohta, H. Murakami, H. Suga
    • Journal Title

      ChemBioChem 9

      Pages: 2773-2778

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16101007
  • [Journal Article] Synthesis of biopolymers using genetic code reprogramming2008

    • Author(s)
      A. Ohta, Y. Yamagishi, H. Suga
    • Journal Title

      Current Opinion in Chemical Biology 12

      Pages: 159-167

    • Data Source
      KAKENHI-PROJECT-16101007
  • [Journal Article] Ribosomal synthesis of nonstandard peptides2008

    • Author(s)
      T.-J. Kang, H. Suga
    • Journal Title

      Biochemistry and Cell Biology 86

      Pages: 92-99

    • Data Source
      KAKENHI-PROJECT-16101007
  • [Journal Article] Messeriger RNA-directed incorporation of multiple N-methyl-amino acids into linear and cyclic peptides2008

    • Author(s)
      T. Kawakami, H. Murakami, H. Suga
    • Journal Title

      Chemistty and Biology 14

      Pages: 32-42

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16101007
  • [Journal Article] Ribosomal synthesisi of polypeptoids and peptoid-peptide hybrids2008

    • Author(s)
      T.Kawakami, H.Murakami, H.Suga
    • Journal Title

      Journal of American Chemical Society 130

      Pages: 16861-16863

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16101007
  • [Journal Article] Reprogramming the initiation event in translation for the synthesis of physiologically stable cyclic peptides2008

    • Author(s)
      Y.Goto, A. Ohta, Y. Sako, Y. Yamagishi, H.Murakami, H. Suga
    • Journal Title

      ACS Chemical Biology 3

      Pages: 120-129

    • Data Source
      KAKENHI-PROJECT-16101007
  • [Journal Article] Symthesis of biopolymers using genetic code reprogramming2008

    • Author(s)
      A. Ohta, Y. Yamagishi, H. Suga
    • Journal Title

      Current Opinion in Chemical Biology 12

      Pages: 159-167

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16101007
  • [Journal Article] Ribosomal synthesis of polypeptoids and peptoid-peptide hybrids2008

    • Author(s)
      T.Kawakami, H. Murakami, H. Suga
    • Journal Title

      Journal of American Chemical Society 130

      Pages: 16861-16863

    • Data Source
      KAKENHI-PROJECT-16101007
  • [Journal Article] Strcutural basis of specific tRNAaminoacylation by a small in vitroselected ribozyme2008

    • Author(s)
      H. Xiao, H. Murakami, H. Suga
    • Journal Title

      A. R. Ferre-D'Amare Nature 454

      Pages: 358-361

    • Data Source
      KAKENHI-PROJECT-16101007
  • [Journal Article] Ribosomal synthesis of nonstandard peptides2008

    • Author(s)
      T. J. Kang, H. Suga
    • Journal Title

      Biochemistry and Cell Biology 86

      Pages: 92-99

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16101007
  • [Journal Article] In vitro selection of a 5'-purine ribonucleotide transferase ribozyme2007

    • Author(s)
      Taek-Jin Kang, Hiroaki Suga
    • Journal Title

      Nucleic Acid Research (In press)

    • Data Source
      KAKENHI-PROJECT-16101007
  • [Journal Article] Re-engineering an in-vitro evolved ribozyme2007

    • Author(s)
      S. Pattnaik, H. Suga
    • Journal Title

      Nucleic Acids Symposium Series 51

      Pages: 381-382

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16101007
  • [Journal Article] The flexizyme system:A highly flexible tRNA aminoacyation tool for thr translation apparatus2007

    • Author(s)
      M. Ohuchi, H. Murakami, H. Suga
    • Journal Title

      Current Opinion in Chemistry and Biology 11

      Pages: 134-144

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16101007
  • [Journal Article] 遺伝暗号リプログラミングによるポリエステルの翻訳合成2007

    • Author(s)
      太田 淳, 村上 裕, 菅 裕明
    • Journal Title

      高分子 56・4月号

      Pages: 196-199

    • Data Source
      KAKENHI-PROJECT-16101007
  • [Journal Article] Synthesis of polyester by means of genetic code reprogramming2007

    • Author(s)
      A. Ohta, H. Murakami, E. Higashimura, H. Suga
    • Journal Title

      Chemistry and Biology 13

      Pages: 1315-1322

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16101007
  • [Journal Article] 特殊ペプチドのコンビナトリアル翻訳合成2007

    • Author(s)
      後藤佑樹, 太田淳, 村上裕, 菅裕明
    • Journal Title

      化学工業 58・4月号

      Pages: 255-262

    • Data Source
      KAKENHI-PROJECT-16101007
  • [Journal Article] 遺伝暗号のリプログラミング2007

    • Author(s)
      佐古 佑介・村上 裕・菅裕 明
    • Journal Title

      蛋白質核酸酵素 52

      Pages: 1643-1648

    • Data Source
      KAKENHI-PROJECT-16101007
  • [Journal Article] In vitro selection of a 5'-purinenucleotide transferase ribozyme2007

    • Author(s)
      T.-J. Kang, H. Suga
    • Journal Title

      Nucleic Acids Symposium Series 51

      Pages: 379-380

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16101007
  • [Journal Article] Exploration of ineorporation of Nalpha-methylated amino acids into peptides by sense-suppression method2007

    • Author(s)
      T. Kawakami, H. Murakami, H. Suga
    • Journal Title

      Nucleic Acids Symposium Series 51

      Pages: 361-362

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16101007
  • [Journal Article] In situ generation of aminoacyl-tRNAs assisted by ribozymes in translation apparatus2007

    • Author(s)
      M. Ohuchi, H. Murakami, H. Suga
    • Journal Title

      Nucleic Acids Symposium Series 51

      Pages: 361-362

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16101007
  • [Journal Article] In vitro evolution of flexizymes that function under the conditions in translation system2006

    • Author(s)
      Masaki Ohuchi, Hiroshi Murakami, Hiroaki Suga
    • Journal Title

      Nucleic Acids Symposium Series 50

      Pages: 299-300

    • Data Source
      KAKENHI-PROJECT-16101007
  • [Journal Article] Translation initiation by using various N-acylaminoacyl tRNAs2006

    • Author(s)
      Yuki Goto, Hiroshi Ashigai, Yusuke Sako, Hiroshi Murakami, Hiroaki Suga
    • Journal Title

      Nucleic Acids Symposium Series 50

      Pages: 293-294

    • Data Source
      KAKENHI-PROJECT-16101007
  • [Journal Article] 合成生物学・その概念と未来2006

    • Author(s)
      木賀大輔, 菅 裕明
    • Journal Title

      バイオニクス・オーム社 3月号

      Pages: 28-33

    • Data Source
      KAKENHI-PROJECT-16101007
  • [Journal Article] Flexizyme as a versatile tRNA acylation catalyst and the application for translation2006

    • Author(s)
      Hiroshi Murakami, Atsushi Ohta, Yuki Goto, Yusuke Sako, Hiroaki Suga
    • Journal Title

      Nucleic Acids Symposium Series 50

      Pages: 35-36

    • Data Source
      KAKENHI-PROJECT-16101007
  • [Journal Article] A highly flexible tRNA acylation system for nonnatural polypeptide synthesis2006

    • Author(s)
      Hiroshi Murakami, Atsushi Ohta, Hiroshi Ashigai, Hiroaki Suga
    • Journal Title

      Nature Methods in press

    • Data Source
      KAKENHI-PROJECT-16101007
  • [Journal Article] Ribosomal synthesis of peptides having various acyl groups on the N-terminus2006

    • Author(s)
      Yuki Goto, Hiroshi Ashigai, Yusuke Sako, Hiroshi Murakami, Hiroaki Suga
    • Journal Title

      Peptide Science 43

      Pages: 46-47

    • NAID

      10020528886

    • Data Source
      KAKENHI-PROJECT-16101007
  • [Journal Article] A highly flexible tRNA acylation system for nonnatural polypeptide synthesis2006

    • Author(s)
      Hiroshi Murakami, Atsushi Ohta, Hiroshi Ashigai, Hiroaki Suga
    • Journal Title

      Nature Methods 3

      Pages: 357-359

    • Data Source
      KAKENHI-PROJECT-16101007
  • [Journal Article] Ribosomal synthesis of non-natural peptide using the flexizyme system2006

    • Author(s)
      Hiroshi Murakami, Atsushi Ohta, Yuki Goto, Yusuke Sako, Hiroaki Suga
    • Journal Title

      Peptide Science 43

      Pages: 48-49

    • NAID

      10020528891

    • Data Source
      KAKENHI-PROJECT-16101007
  • [Journal Article] A novel therapeutic approach for genetic diseases by introduction of suppressor tRNA2006

    • Author(s)
      Yusuke Sako, Fusako Usuki, Hiroaki Suga
    • Journal Title

      Nucleic Acids Symposium Series 50

      Pages: 239-240

    • Data Source
      KAKENHI-PROJECT-16101007
  • [Journal Article] フレキシザイムを用いた遺伝暗号の拡張とリプログラミング2006

    • Author(s)
      村上 裕, 菅 裕明
    • Journal Title

      蛋白質核酸酵素 51・16

      Pages: 28-33

    • Data Source
      KAKENHI-PROJECT-16101007
  • [Journal Article] セントラルドグマをつくりかえる2006

    • Author(s)
      村上 裕, 菅 裕明, 平尾一郎
    • Journal Title

      バイオニクス・オーム社 3月号

      Pages: 34-39

    • Data Source
      KAKENHI-PROJECT-16101007
  • [Journal Article] 細胞内情報をあやつる2006

    • Author(s)
      築地真也, 菅 裕明, 長棟輝行
    • Journal Title

      バイオニクス・オーム社 3月号

      Pages: 46-51

    • Data Source
      KAKENHI-PROJECT-16101007
  • [Journal Article] フレキシザイム-遺伝暗号の拡張とリプログラミングへの応用2006

    • Author(s)
      村上 裕, 菅 裕明
    • Journal Title

      バイオテクノロジージャーナル 6・11/12月号

      Pages: 2496-2501

    • Data Source
      KAKENHI-PROJECT-16101007
  • [Journal Article] 人工リボザイムでRNAワールドの検証に挑む2005

    • Author(s)
      菅 裕明
    • Journal Title

      現代化学 6月号

      Pages: 44-50

    • NAID

      40006766368

    • Data Source
      KAKENHI-PROJECT-16101007
  • [Journal Article] Programmable ribozymes for misoharging tRNA with nonnatural amino acids and their applications to translation2005

    • Author(s)
      Dimitrios Kourouklis, Hiroshi Murakami, Hiroaki Suga
    • Journal Title

      Methods 36(3)

      Pages: 239-244

    • Data Source
      KAKENHI-PROJECT-16101007
  • [Journal Article] Ribozymes that use redox cofactors2004

    • Author(s)
      S.Tsukiji, K.Ramaswamy, H.Suga
    • Journal Title

      Journal Pure and Applied Chemistry 76

      Pages: 1525-1536

    • Data Source
      KAKENHI-PROJECT-16101007
  • [Journal Article] Reduction of an aldehyde by a NADH/Zn^<2+>-dependent redox active ribozyme2004

    • Author(s)
      S.Tsukiji, S.Pattnaik, H.Suga
    • Journal Title

      Journal of American Chemical Society 126

      Pages: 5044-5045

    • Data Source
      KAKENHI-PROJECT-16101007
  • [Patent] D-アミノ酸及びβ-アミノ酸の取り込みを増強するtRNAのD及びTアームの改変2018

    • Inventor(s)
      菅 裕明,加藤 敬行
    • Industrial Property Rights Holder
      菅 裕明,加藤 敬行
    • Industrial Property Rights Type
      特許
    • Filing Date
      2018
    • Overseas
    • Data Source
      KAKENHI-PROJECT-26220204
  • [Patent] 多種の非タンパク質性アミノ酸を利用できるカスタムメイドペプチド翻訳合成系2018

    • Inventor(s)
      菅 裕明,加藤 敬行,岩根 由彦
    • Industrial Property Rights Holder
      菅 裕明,加藤 敬行,岩根 由彦
    • Industrial Property Rights Type
      特許
    • Filing Date
      2018
    • Data Source
      KAKENHI-PROJECT-26220204
  • [Patent] ペプチドライブラリーの製造方法2018

    • Inventor(s)
      菅 裕明,後藤 佑樹,阿部 郁朗,岡田 正弘,井上 澄香
    • Industrial Property Rights Holder
      国立大学法人東京大学
    • Industrial Property Rights Type
      特許
    • Filing Date
      2018
    • Data Source
      KAKENHI-PLANNED-16H06444
  • [Patent] 化合物ライブラリー及び化合物ライブラリーの製造方法2018

    • Inventor(s)
      菅 裕明,後藤 佑樹,尾仲 宏康,ヴィノグラドフ アレクサンダー
    • Industrial Property Rights Holder
      国立大学法人東京大学
    • Industrial Property Rights Type
      特許
    • Filing Date
      2018
    • Data Source
      KAKENHI-PLANNED-16H06444
  • [Patent] C-Metタンパク質アゴニスト2013

    • Inventor(s)
      菅裕明、伊藤健一郎
    • Industrial Property Rights Holder
      東京大学
    • Filing Date
      2013-10-15
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Patent] MATE活性阻害ペプチド2013

    • Inventor(s)
      菅裕明、濡木理、クリストファージェイ ヒポライト、田中良樹
    • Industrial Property Rights Holder
      東京大学
    • Filing Date
      2013-07-28
    • Overseas
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Patent] MATE 活性阻害ペプチド2013

    • Inventor(s)
      菅裕明、濡木理、ヒポリト クリストファー、田中良樹
    • Industrial Property Rights Holder
      東京大学
    • Filing Date
      2013-07-28
    • Overseas
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Patent] 大環状ペプチド、その製造方法、及び大環状ペプチドライブラリを用いるスクリーニング方法2013

    • Inventor(s)
      菅裕明
    • Industrial Property Rights Holder
      東京大学
    • Industrial Property Rights Type
      特許
    • Filing Date
      2013-08-26
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Patent] c-Metタンパク質アゴニスト2013

    • Inventor(s)
      菅裕明, 伊藤健一郎
    • Industrial Property Rights Holder
      東京大学
    • Industrial Property Rights Type
      特許
    • Filing Date
      2013-10-15
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Patent] 大環状ペプチド、その製造方法、及び大環状ペプチドライブラリを用いるスクリーニング方法2013

    • Inventor(s)
      菅裕明
    • Industrial Property Rights Holder
      東京大学
    • Filing Date
      2013-08-26
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Patent] MATE活性阻害ペプチド2012

    • Inventor(s)
      菅裕明、濡木理、クリストファー ヒポリト、田中良樹
    • Industrial Property Rights Holder
      菅裕明、濡木理、クリストファー ヒポリト、田中良樹
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2012-170144
    • Filing Date
      2012-07-31
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Patent] アゾリン化合物及びアゾール化合物のライブラリー、並びにその製造方法2012

    • Inventor(s)
      菅裕明・後藤佑樹・伊藤悠美
    • Industrial Property Rights Holder
      国立大学法人東京大学
    • Filing Date
      2012-03-09
    • Overseas
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Patent] pH依存的に標的分子に結合するペプチドのスクリーニング方法2012

    • Inventor(s)
      菅裕明、飯田健夫
    • Industrial Property Rights Holder
      菅裕明、飯田健夫
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2012-129056
    • Filing Date
      2012-06-06
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Patent] アゾリン化合物およびアゾール化合物のライブラリー、並びにその製造方法2011

    • Inventor(s)
      菅裕明, 後藤佑樹, 伊藤悠美
    • Industrial Property Rights Holder
      東京大学
    • Industrial Property Number
      2010-190315
    • Filing Date
      2011-03-19
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Patent] 安定化された二次構造を有するペプチド、及びペプチドライブラリー、それらの製造方法2011

    • Inventor(s)
      菅裕明、樋口岳
    • Industrial Property Rights Holder
      東京大学
    • Acquisition Date
      2011-12-05
    • Overseas
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Patent] 安定化された二次構造を有するペプチド、及びペプチドライブラリー、それらの製造方法2011

    • Inventor(s)
      菅裕明、樋口岳
    • Industrial Property Rights Holder
      東京大学
    • Industrial Property Rights Type
      特許
    • Filing Date
      2011-12-05
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Patent] 新規人工翻訳合成系2011

    • Inventor(s)
      菅裕明・村上裕・後藤佑樹
    • Industrial Property Rights Holder
      国立大学法人東京大学
    • Filing Date
      2011-08-26
    • Overseas
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Patent] ペプチドライブラリーの製造方法、ペプチドライブラリー、およびスクリーニング方法2011

    • Inventor(s)
      菅裕明, 森本淳平
    • Industrial Property Rights Holder
      国立大学法人東京大学
    • Filing Date
      2011-12-05
    • Overseas
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Patent] 安定化された二次構造を有するペプチド、およびペプチドライブラリー、それらの製造方法2011

    • Inventor(s)
      菅裕明, 樋口岳
    • Industrial Property Rights Holder
      国立大学法人東京大学
    • Filing Date
      2011-12-05
    • Overseas
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Patent] N-メチルアミノ酸おびその他の特殊アミノ酸を含む特殊ペプチド化合物ライブラリーの翻訳構築と活性種探索法2011

    • Inventor(s)
      菅裕明, 山岸祐介
    • Industrial Property Rights Holder
      国立大学法人東京大学
    • Filing Date
      2011-09-08
    • Overseas
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Patent] 新規人工翻訳合成系2010

    • Inventor(s)
      菅裕明・村上裕・後藤佑樹
    • Industrial Property Rights Holder
      東京大学
    • Industrial Property Number
      2010-190315
    • Filing Date
      2010-08-27
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Patent] N・メチルアミノ酸およびその他の特殊アミノ酸を含む特殊ペプチド化合物ライブラリーの翻訳構築と活性種探索法2010

    • Inventor(s)
      菅裕明, 山岸祐介
    • Industrial Property Rights Holder
      東京大学
    • Industrial Property Number
      2010-202012
    • Filing Date
      2010-09-09
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Patent] αヘリックス2次元構造を固定した特殊ペプチド化合物ライブラリーの合成法と活性種探索法2010

    • Inventor(s)
      菅裕明, 樋口岳
    • Industrial Property Rights Holder
      東京大学
    • Industrial Property Number
      2010-270958
    • Filing Date
      2010-12-03
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Patent] 特異的機能低分子化合物含有特殊ペプチドのライブラリーの合成法と活性種探索法2010

    • Inventor(s)
      菅裕明, 森本淳平
    • Industrial Property Rights Holder
      東京大学
    • Industrial Property Number
      2010-270507
    • Filing Date
      2010-12-03
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Patent] 環状化学物ペプチドの合成法2007

    • Inventor(s)
      菅 裕明, 村上 裕, 後藤佑樹, 山岸祐介, 足海洋史, 佐古佑介
    • Industrial Property Rights Holder
      東京大学
    • Industrial Property Number
      2007-080141
    • Filing Date
      2007-03-26
    • Data Source
      KAKENHI-PROJECT-16101007
  • [Patent] N末端に非天然骨格を持つポリペプチドの翻訳合成とその応用2006

    • Inventor(s)
      菅 裕明, 村上 裕, 後藤佑樹, 太田 淳
    • Industrial Property Rights Holder
      東京大学
    • Industrial Property Number
      2006-312000
    • Filing Date
      2006-11-17
    • Data Source
      KAKENHI-PROJECT-16101007
  • [Presentation] 基礎研究からイノベーションへ2024

    • Author(s)
      菅 裕明
    • Organizer
      2024新春特別フォーラム
    • Invited
    • Data Source
      KAKENHI-PROJECT-20H05618
  • [Presentation] 特殊環状ペプチド創薬からネオバイオロジクス創薬へ2023

    • Author(s)
      Hiroaki Suga
    • Organizer
      第96回日本整形外科学会学術総会
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H05618
  • [Presentation] De novo discovery of pseud-natural peptides and products2023

    • Author(s)
      Hiroaki Suga
    • Organizer
      49th IUPAC World Chemistry Congress
    • Invited
    • Data Source
      KAKENHI-PROJECT-20H05618
  • [Presentation] 特殊ペプチド創薬から擬天然物創薬、ネオバイオロジクス創薬2023

    • Author(s)
      菅 裕明
    • Organizer
      第40回メディシナルケミストリーシンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-20H05618
  • [Presentation] De novo discovery of pseudo-natural peptides, products, and beyond2023

    • Author(s)
      Hiroaki Suga
    • Organizer
      16th German Peptide Symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H05618
  • [Presentation] 『基礎研究から創薬イノベーションへ ―特殊ペプチド創薬・ネオバイオロジクス創薬―』2023

    • Author(s)
      菅 裕明
    • Organizer
      高知工科 大学 高知県立大学 高知工業高等専門学校 高知大学医工連携交流会 with 高知大学 MEDi センターキックオフ講演会 招待講演
    • Invited
    • Data Source
      KAKENHI-PROJECT-20H05618
  • [Presentation] Libraries and Display Selection for Macrocycles with Better Membrane Permeability2023

    • Author(s)
      Hiroaki Suga
    • Organizer
      18th Drug Discovery Chemistry
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H05618
  • [Presentation] Display and RaPID Selection of Pseudo-Natural Peptides and Products2022

    • Author(s)
      菅 裕明
    • Organizer
      Boulder Peptide Symposium 2022
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H05618
  • [Presentation] The next generation RaPID system2022

    • Author(s)
      菅 裕明
    • Organizer
      Peptide Therapeutics Forum 2022
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H05618
  • [Presentation] The Next Generation RaPID System2022

    • Author(s)
      菅 裕明
    • Organizer
      27th American Peptide Symposium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H05618
  • [Presentation] The Next Generation of RaPID System2022

    • Author(s)
      菅 裕明
    • Organizer
      The 17thAnnual Peptide Therapeutics Symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H05618
  • [Presentation] The RaPID system that revolutionizes the discovery of de novo peptides and proteins for therapeutics2022

    • Author(s)
      菅 裕明
    • Organizer
      Prelog Lecture 2020
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H05618
  • [Presentation] "RaPID Development of Pseudo-Natural Peptides/Products and Neobiologics"2022

    • Author(s)
      菅 裕明
    • Organizer
      T. Y. Shen Seminar in Biological Chemistry
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H05618
  • [Presentation] Display of pseud-natural peptides and products2022

    • Author(s)
      菅 裕明
    • Organizer
      Chemical Biology & Physiology 21|22(Drug Discovery)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H05618
  • [Presentation] Displayable Pseudo-Natural Peptides and Products2021

    • Author(s)
      Hiroaki Suga
    • Organizer
      The 18th Akabori Conference
    • Invited
    • Data Source
      KAKENHI-PROJECT-20H05618
  • [Presentation] 特殊ペプチドによる創薬革命2020

    • Author(s)
      Hiroaki Suga
    • Organizer
      第79回日本癌学会学術総会
    • Invited
    • Data Source
      KAKENHI-PLANNED-16H06444
  • [Presentation] The next generation of RaPID display2020

    • Author(s)
      Hiroaki Suga
    • Organizer
      RSC Desktop Seminar
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H05618
  • [Presentation] Displayable Pseudo-Natural Products2020

    • Author(s)
      Hiroaki Suga
    • Organizer
      Gordon Research Conferences: Advancing Peptides as Tools, Materials and Therapeutics
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06444
  • [Presentation] The next generation of RaPID display2020

    • Author(s)
      Hiroaki Suga
    • Organizer
      RSC Desktop Seminar
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06444
  • [Presentation] Revolutionizing the discovery processes of macrocyclic peptide therapeutics: A show case of anti-PlexinB1 peptides2020

    • Author(s)
      Hiroaki Suga
    • Organizer
      14th International Conference on Protein Phosphatase Japan Bone Academy 2020
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H05618
  • [Presentation] The power of RaPID system for de novo macrocycles discovery2020

    • Author(s)
      Hiroaki Suga
    • Organizer
      Target 2035 A prove for every protein Kick-off webinar series Asia/Pacific session
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H05618
  • [Presentation] From Basic Science to Innovation - From genetic code reprogramming to peptide therapeutics2020

    • Author(s)
      Hiroaki Suga
    • Organizer
      MIRAI Seminar
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06444
  • [Presentation] From Basic Science to Innovation -From genetic code reprogramming to peptide therapeutics2020

    • Author(s)
      Hiroaki Suga
    • Organizer
      MIRAI 2.0 Japanese-Swedish Joint Kick-off/Scientific Webinar
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H05618
  • [Presentation] 特殊ペプチド医薬品スクリーニングの革命2020

    • Author(s)
      Hiroaki Suga
    • Organizer
      第10回レギュラトリーサイエンス学会学術大会
    • Invited
    • Data Source
      KAKENHI-PLANNED-16H06444
  • [Presentation] 特殊ペプチド創薬からネオバイオロジクス創薬2020

    • Author(s)
      Hiroaki Suga
    • Organizer
      第24回日本がん分子標的治療学会学術集会
    • Invited
    • Data Source
      KAKENHI-PLANNED-16H06444
  • [Presentation] From constrained peptides to neobiologics2020

    • Author(s)
      Hiroaki Suga
    • Organizer
      AsiaTIDES: Oligonucleotide & Peptide Therapeutics
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06444
  • [Presentation] From Constrained Peptides to NeoBiologics2019

    • Author(s)
      Hiroaki Suga
    • Organizer
      The 8thChemical Protein Synthesis (CPS) Meeting 2019
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06444
  • [Presentation] Revolutionizing the discovery process of peptide drug leads by the RaPID system2019

    • Author(s)
      Hiroaki Suga
    • Organizer
      26th International smposium: Synthesis in organic chemistry
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06444
  • [Presentation] The RaPID way to devise biologically active peptides and biologics2019

    • Author(s)
      Hiroaki Suga
    • Organizer
      20th Tetrahedron Symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06444
  • [Presentation] Macrocyclic pseudo-natural peptides for anti-cancer therapies2019

    • Author(s)
      H Suga
    • Organizer
      11th AACR-JCA Joint Conference on Breakthroughs in Cancer Research: Biology to Precision Medicine
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06444
  • [Presentation] Rvolutionizing the discovery processes of de novo bioactive peptidesand biologics2019

    • Author(s)
      Hiroaki Suga
    • Organizer
      27th International Society of Heterocyclic Chemistry Congress
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06444
  • [Presentation] Unnatural Amino Acids for Exotic Macrocyclic Peptides and Targeting IL6R as a Case Study2019

    • Author(s)
      Hiroaki Suga
    • Organizer
      Drug Discovery Chemistry
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06444
  • [Presentation] Revolutionizing the discovery processes of therapeutically valuable peptides and biologics2019

    • Author(s)
      Hiroaki Suga
    • Organizer
      47th IUPAC Chemistry Congress
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06444
  • [Presentation] Revolutionizing the discovery process of macrocyclic peptides for therapeutic use2019

    • Author(s)
      Hiroaki Suga
    • Organizer
      21st GFPP Meeting
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06444
  • [Presentation] Peptide therapeutics innovation2019

    • Author(s)
      Hiroaki Suga
    • Organizer
      The 78th Annual Meeting of the Japanese Cancer Assocation
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06444
  • [Presentation] Revolutionizing the discovery processes of de novo bioactive peptides and biologics2019

    • Author(s)
      Hiroaki Suga
    • Organizer
      Bohlmann Lecture Freie University Berlin
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06444
  • [Presentation] De novo discovery of bioactive pseudo-natural peptides from biosynthetic libraries2019

    • Author(s)
      Hiroaki Suga
    • Organizer
      30th Anniversary Today-Unistra Symposium on Complexity
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06444
  • [Presentation] In vitro pseudo-natural product biosynthesis and selection2019

    • Author(s)
      Hiroaki Suga
    • Organizer
      14th International Symposium on the Genetics of Industrial Microorganisms (GIM) 2019
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06444
  • [Presentation] Revolutionizing the discovery processes of de novo bioactive peptides and neobiologics2019

    • Author(s)
      Hiroaki Suga
    • Organizer
      34th William S. Johnson Symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06444
  • [Presentation] From constrained peptides to biologics2019

    • Author(s)
      H Suga
    • Organizer
      The Festival of Biologics San Diego
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06444
  • [Presentation] Revolutionizing the discovery process de novo bioactive peptides and biologics2019

    • Author(s)
      Hiroaki Suga
    • Organizer
      5th Peptides & Proteins Symposium Singapre
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06444
  • [Presentation] Revolutionizing the Discovery Processes of de novo Bioactive Peptides and Biologics2019

    • Author(s)
      Hiroaki Suga
    • Organizer
      26th American Peptide Symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06444
  • [Presentation] Worldwide Perspectives on SynCell2019

    • Author(s)
      Hiroaki Suga
    • Organizer
      SynCell2019: Defining the Challenges
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06444
  • [Presentation] 擬天然ペプチドのリボソーム型生体外発現に関する最近の研究成果2019

    • Author(s)
      H Suga
    • Organizer
      AsiaTIDES: Oligonucleotide & Peptide Therapeutics
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06444
  • [Presentation] Revolutionizing the discovery process of bioactive peptides2019

    • Author(s)
      Hiroaki Suga
    • Organizer
      RU Lemieux Lecture on Biotechnology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06444
  • [Presentation] The RaPID way to discover bioactive pseudo-natural macrocycles2018

    • Author(s)
      H Suga
    • Organizer
      10th International Peptide Symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06444
  • [Presentation] "The RaPID way to discover bioactive pseudo-natural peptides with macrocyclic scaffold"2018

    • Author(s)
      H Suga
    • Organizer
      The Protein Society Annual Symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26220204
  • [Presentation] The RaPID way to discover bioactive pseudo-natural macrocycles2018

    • Author(s)
      H Suga
    • Organizer
      10th International Peptide Symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26220204
  • [Presentation] Revolutionizing the discovery process of bioactive peptides2018

    • Author(s)
      H Suga
    • Organizer
      Basel Life 2018
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26220204
  • [Presentation] The RaPID System That Has Revolutionized the Discovery Process of Peptide Therapeutics2018

    • Author(s)
      H Suga
    • Organizer
      ACS Publications Symposium: Innovation at the Frontier of Chemistry and Life Science
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06444
  • [Presentation] The RaPID discovery of bioactive pseudo-natural peptides2018

    • Author(s)
      H Suga
    • Organizer
      CHI's 13th Annual Drug Discovery Chemistry
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26220204
  • [Presentation] The RaPID Discovery of Bioactive Pseudo-Natural Peptides2018

    • Author(s)
      H Suga
    • Organizer
      1st Japanese-German Symposium Biosynthesis and Function of Natural Products
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06444
  • [Presentation] 擬天然ペプチドのリボソーム型生体外発現に関する最近の研究成果2018

    • Author(s)
      H Suga
    • Organizer
      AsiaTIDES: Oligonucleotide & Peptide Therapeutics
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26220204
  • [Presentation] Revolutionizing the discovery process of peptide drug leads2018

    • Author(s)
      H Suga
    • Organizer
      Nature Conference on Chemical Biology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06444
  • [Presentation] The RaPID discovery of bioactive pseudo-natural peptides2018

    • Author(s)
      H Suga
    • Organizer
      CHI's 13th Annual Drug Discovery Chemistry
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06444
  • [Presentation] From constrained peptides to biologics2018

    • Author(s)
      H Suga
    • Organizer
      The Festival of Biologics San Diego
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26220204
  • [Presentation] The RaPID System That Has Revolutionized the Discovery Process of Peptide Therapeutics2018

    • Author(s)
      H Suga
    • Organizer
      ACS Publications Symposium: Innovation at the Frontier of Chemistry and Life Science
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26220204
  • [Presentation] Revolutionizing the discovery process of bioactive peptides2018

    • Author(s)
      H Suga
    • Organizer
      Basel Life 2018
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06444
  • [Presentation] Revolutionizing the discovery process of peptide drug leads2018

    • Author(s)
      H Suga
    • Organizer
      Nature Conference on Chemical Biology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26220204
  • [Presentation] The RaPID way to discover bioactive pseudo-natural peptides with macrocyclic scaffold2018

    • Author(s)
      H Suga
    • Organizer
      The Protein Society Annual Symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06444
  • [Presentation] The RaPID Discovery of Bioactive Pseudo-Natural Peptides2018

    • Author(s)
      H Suga
    • Organizer
      1st Japanese-German Symposium Biosynthesis and Function of Natural Products
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26220204
  • [Presentation] The RaPID way to discover bioactive macrocyclic peptides expressed under the reprogrammed genetic code2018

    • Author(s)
      H Suga
    • Organizer
      2018 Genetic Code Espansion Conference
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06444
  • [Presentation] Macrocyclic pseudo-natural peptides for anti-cancer therapies2018

    • Author(s)
      H Suga
    • Organizer
      11th AACR-JCA Joint Conference on Breakthroughs in Cancer Research: Biology to Precision Medicine
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26220204
  • [Presentation] The RaPID way to discover bioactive macrocyclic peptides expressed under the reprogrammed genetic code2018

    • Author(s)
      H Suga
    • Organizer
      2018 Genetic Code Espansion Conference
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26220204
  • [Presentation] One-Pot Synthesis and Screening of Pseudo-Natural Peptides and Products2017

    • Author(s)
      H Suga
    • Organizer
      The Bioorganic Chemistry Gordon Research Conference
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06444
  • [Presentation] Inorporation of nonproteinogenic amino acids into polypeptides from protein functional studies to drug discovery2017

    • Author(s)
      H Suga
    • Organizer
      The Ins-and-Outs of Membrane Biolog
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06444
  • [Presentation] One-Pot Synthesis and Screening of Pseudo-Natural Peptides and Products2017

    • Author(s)
      Hiroaki Suga
    • Organizer
      2017 Bioorganic Chemistry Gordon Conference
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26220204
  • [Presentation] The RaPID discovery of bioactive pseudo-natural peptides2017

    • Author(s)
      H Suga
    • Organizer
      Nanoscience Days 2017
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06444
  • [Presentation] A RaPID way to discover pseudo-natural peptides and products2017

    • Author(s)
      H Suga
    • Organizer
      Benzon Symposium; New Paradigms of Protein Engineering & Applications in Modern Medicine
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06444
  • [Presentation] A RaPID way to discover pseudo-natural peptides and products for therapeutic uses2017

    • Author(s)
      H Suga
    • Organizer
      14th Horizons in Molecular Biology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06444
  • [Presentation] A RaPID Way to Discover Pseudo-natural Peptides and Products for Therapeutic Uses2017

    • Author(s)
      Hiroaki Suga
    • Organizer
      Dutch peptide symposium 2017
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26220204
  • [Presentation] The RaPID Discovery of Pseudo-Natural Peptides2017

    • Author(s)
      H Suga
    • Organizer
      25th American Peptide Symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06444
  • [Presentation] A RaPID Way to Discover Pseudo-natural Peptides and Products for Therapeutic Uses2017

    • Author(s)
      H Suga
    • Organizer
      Dutch Peptide Symposium 2017
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06444
  • [Presentation] RaPID Way to Discover Pseudo-natural Peptides for Therapeutic Uses2017

    • Author(s)
      Hiroaki Suga
    • Organizer
      GDCh Scientific Forum Chemistry 2017
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26220204
  • [Presentation] RaPID Way to Discover Pseudo-natural Peptides for Therapeutic Uses2017

    • Author(s)
      H Suga
    • Organizer
      GDCh Scientific Forum Chemistry 2017
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06444
  • [Presentation] Translation-coupled in vitro reconstitution of pseudo-natural peptide biosynthesis2017

    • Author(s)
      Hiroaki Suga
    • Organizer
      9th US-Japan Seminar on the Biosynthesis of Natural Products
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26220204
  • [Presentation] A RaPID way to discover pseudo-natural peptides and products Discussion2017

    • Author(s)
      Hiroaki Suga
    • Organizer
      Benzon Symposium 63-New Paradigms of Protein Engineering-Applications in Modern Medicine
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26220204
  • [Presentation] A RaPID way to discover bioactive pseudo-natural peptides2017

    • Author(s)
      H Suga
    • Organizer
      26th French-Japanese Symposium on Medicinal & Fine Chemistry
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06444
  • [Presentation] Genetic code reprogramming assisted by flexizymes and pseudo-natural peptide discovery2017

    • Author(s)
      Hiroaki Suga
    • Organizer
      AARS2017 (2017 IUBMB Focused Meeting on Aminoacyl-tRNA Synthetases
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26220204
  • [Presentation] The RaPID Discovery of Pseudo-Natural Peptides2017

    • Author(s)
      Hiroaki Suga
    • Organizer
      25th American Peptide Symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26220204
  • [Presentation] A RaPID way to discover pseudo-natural peptides for therapeutic uses2017

    • Author(s)
      H Suga
    • Organizer
      11th International Symposium on Bioorganic Chemistry
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06444
  • [Presentation] A RaPID Way to Discover Bioactive Pseudo-Natural Peptides2017

    • Author(s)
      Hiroaki Suga
    • Organizer
      Perspectives in Molecular Pharmacology 25 Years FMP
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26220204
  • [Presentation] A RaPID Way to Discover Bioactive Pseudo-Natural Peptides2017

    • Author(s)
      H Suga
    • Organizer
      Symposium and celebrations of the 25th anniversary of the Leibniz-Institut fur Molekulare Pharmakologie
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06444
  • [Presentation] A RaPID Way to Discover Pseudo-natural Peptides2017

    • Author(s)
      Hiroaki Suga
    • Organizer
      7th Symposium on Advances in Synthetic and Medicinal
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26220204
  • [Presentation] A RaPID way to discover bioactive pseudo-natural peptides2017

    • Author(s)
      Hiroaki Suga
    • Organizer
      26th French-Japanese Symposium on Medicinal and Fine Chemistry
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26220204
  • [Presentation] A RaPID Way to Discover Pseudo-natural Peptides2017

    • Author(s)
      H Suga
    • Organizer
      7th Symposium on Advances in Synthetic and Medicinal Chemistry
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06444
  • [Presentation] Genetic code reprogramming assisted by flexizymes and pseudo-natural peptide discovery2017

    • Author(s)
      H Suga
    • Organizer
      AARS2017 (2017 IUBMB Focused Meeting on Aminoacyl-tRNA Synthetases)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06444
  • [Presentation] Inorporation of nonproteinogenic amino acids into polypeptides from protein functional studies to drug discovery2017

    • Author(s)
      Hiroaki Suga
    • Organizer
      The Ins-and-Outs of Membrane Biology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26220204
  • [Presentation] Translation-coupled in vitro reconstitution of pseudo-natural peptide biosynthesis2017

    • Author(s)
      H Suga
    • Organizer
      9th US-Japan Seminar on the Biosynthesis of Naural Products
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06444
  • [Presentation] A RaPID way to discover pseudo-natural peptides for therapeutic uses2017

    • Author(s)
      Hiroaki Suga
    • Organizer
      11th International Symposium of Bioorganic Chemistry
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26220204
  • [Presentation] The RaPID discovery of bioactive pseudo-natural peptides2017

    • Author(s)
      Hiroaki Suga
    • Organizer
      Nanoscience Days 2017
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26220204
  • [Presentation] A RaPID way to discover bioactive pseudo-naturla peptides2016

    • Author(s)
      Hiroaki Suga
    • Organizer
      International RNA meeting 2016
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26220204
  • [Presentation] In vitro biosynthetic system for peptides with diverse modified backbones2016

    • Author(s)
      Yuki Goto, Yasuharu Kato, Hiroaki Suga
    • Organizer
      Asian Chemical Biology Conference 2016
    • Place of Presentation
      高雄、台湾
    • Year and Date
      2016-12-01
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06444
  • [Presentation] n vitro synthetic biology of the ribosome and genetic code: From basic science to applied research2016

    • Author(s)
      Hiroshi Suga
    • Organizer
      Symposium on the Genetics of Industrial Microorganisms GIM2016
    • Place of Presentation
      Wuhan, China
    • Year and Date
      2016-10-19
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06444
  • [Presentation] A RaPID way to discover pseudo-natural peptides for therapeutic uses2016

    • Author(s)
      Hiroshi Suga
    • Organizer
      EMBO Conference-Chemical Biology
    • Place of Presentation
      Heidelberg, Germany
    • Year and Date
      2016-09-02
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06444
  • [Presentation] A RaPID way to discover pseudo-natural peptides for therapeutic uses2016

    • Author(s)
      Hiroshi Suga
    • Organizer
      Gold Medal Awardee Lecture, Max-Bergmann Conference 2016
    • Place of Presentation
      Ilsenburg, Germany
    • Year and Date
      2016-10-11
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06444
  • [Presentation] 特殊環状ペプチドによる人工Metアゴニスト.2016

    • Author(s)
      Miao Wenyu、酒井克也、小澤直也、伊藤健一郎、菅裕明、松本邦夫
    • Organizer
      第89回日本生化学会大会
    • Place of Presentation
      仙台国際センター・東北大学 仙台市
    • Year and Date
      2016-09-25
    • Data Source
      KAKENHI-PROJECT-15K14473
  • [Presentation] In vitro synthetic biology of the ribosome and genetic code: From basic science to applied research2016

    • Author(s)
      Hiroaki Suga
    • Organizer
      Symposium on the Genetics of Industrial Microorganisms GIM2016
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26220204
  • [Presentation] A RaPID way to discover pseudo-natural peptides for therapeutic uses2016

    • Author(s)
      Hiroaki Suga
    • Organizer
      EMBO Conference-Chemical Biology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26220204
  • [Presentation] Nomtraditional peptides and pseudo-natural products2016

    • Author(s)
      Hiroaki Suga
    • Organizer
      The 8th Takeda Science Foundation International Symposium on PharmaSciences
    • Invited
    • Data Source
      KAKENHI-PROJECT-26220204
  • [Presentation] A RaPID way to discover bioactive pseudo-naturla peptides2016

    • Author(s)
      Hiroshi Suga
    • Organizer
      Banyu-Sapporo Symposium
    • Place of Presentation
      北海道大学(北海道札幌市)
    • Year and Date
      2016-07-02
    • Invited
    • Data Source
      KAKENHI-PLANNED-16H06444
  • [Presentation] A RaPID way to discover bioactive pseudo-naturla peptides2016

    • Author(s)
      Hiroaki Suga
    • Organizer
      Banyu-Fukuoka Symposium
    • Invited
    • Data Source
      KAKENHI-PROJECT-26220204
  • [Presentation] A RaPID way to discover bioactive pseudo-naturla peptides2016

    • Author(s)
      Hiroaki Suga
    • Organizer
      EMBO Conference-Chemical Biology 2016
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26220204
  • [Presentation] A RaPID way to discover pseudo-natural peptides for therapeutic uses2016

    • Author(s)
      Hiroaki Suga
    • Organizer
      Gold Medal Awardee Lecture, Max-Bergmann Conference 2016
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26220204
  • [Presentation] A RaPID way to discover pseudo-natural products & peptides for therapeutic uses2016

    • Author(s)
      Hiroshi Suga
    • Organizer
      The 1st international PSL Chemical Biology Symposium
    • Place of Presentation
      Paris, France
    • Year and Date
      2016-12-09
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06444
  • [Presentation] A RaPID way to discover pseudo-natural products & peptides for therapeutic uses2016

    • Author(s)
      Hiroaki Suga
    • Organizer
      The 1st international PSL Chemical Biology Symposium 2016
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26220204
  • [Presentation] Ribosomal synthesis of highly N- and O-methylated cyclic peptide libraries for selection of protein-protein interaction inhibitors with “drug-like” characteristics.2015

    • Author(s)
      菅 裕明
    • Organizer
      The 11th Australian Peptide Conference
    • Place of Presentation
      Peppers Salt Resort & Spa, Australia
    • Year and Date
      2015-10-25
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26220204
  • [Presentation] 特殊ペプチド創薬イノベーション2015

    • Author(s)
      菅 裕明
    • Organizer
      Joint International Symposium on TGF-beta and Cancer
    • Place of Presentation
      筑波国際会議場、日本
    • Year and Date
      2015-01-11
    • Invited
    • Data Source
      KAKENHI-PROJECT-26220204
  • [Presentation] 特殊環状ペプチドによるMet/HGF受容体アゴニストの創製2015

    • Author(s)
      松本邦夫、酒井克也、伊藤健一郎、菅裕明
    • Organizer
      インターフェロン・サイトカイン学会
    • Place of Presentation
      東京工業大学(東京都目黒区大岡山)
    • Year and Date
      2015-07-18
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K14473
  • [Presentation] 特殊環状ペプチドによる人工HGFの創製2015

    • Author(s)
      松本邦夫、酒井克也、伊藤健一郎、菅裕明
    • Organizer
      肝細胞研究会
    • Place of Presentation
      米子コンベンションセンター(鳥取県米子)
    • Year and Date
      2015-06-05
    • Data Source
      KAKENHI-PROJECT-15K14473
  • [Presentation] Rapid way for the discovery of macrocyclic peptide drug leads:RaPID way to discover PPI agonists and antagonists2015

    • Author(s)
      菅 裕明
    • Organizer
      The Innternational chemical congress of Pacific Basin Societies 2015
    • Place of Presentation
      Hawaii Convention Center, Honolulu, Hawaii USA
    • Year and Date
      2015-12-15
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26220204
  • [Presentation] A RaPID way for the discovery of pseud-natural products2015

    • Author(s)
      菅 裕明
    • Organizer
      36th National Organic Chemistry Congress
    • Place of Presentation
      Alma Mater Studiorum University, Bologna, Italy
    • Year and Date
      2015-09-13
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26220204
  • [Presentation] Pseudo-Natural Products and Peptides for Therapeutic Applications2015

    • Author(s)
      菅 裕明
    • Organizer
      High Throughput Chemistry & Chemical Biology(GordonResearch Conference)
    • Place of Presentation
      Colby-Sawyer College, New London, NH USA
    • Year and Date
      2015-06-14
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26220204
  • [Presentation] 特殊ペプチド創薬イノベーション:創薬のゲームチェンジを目指して2015

    • Author(s)
      菅 裕明
    • Organizer
      BMB2015
    • Place of Presentation
      神戸国際会議場(兵庫県神戸市中央区島中町)、日本
    • Year and Date
      2015-12-02
    • Invited
    • Data Source
      KAKENHI-PROJECT-26220204
  • [Presentation] Drug-like non-canonical cyclic peptides selected from diverse libraries2015

    • Author(s)
      菅 裕明
    • Organizer
      The third edition of the International Conference on Circular Proteins(ICCP2015)
    • Place of Presentation
      Moreton island, at the Tangalooma Resort, Australia
    • Year and Date
      2015-11-01
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26220204
  • [Presentation] 環状ペプチドによる人工Met受容体アゴニストの創製2015

    • Author(s)
      酒井克也、伊藤健一郎、菅裕明、松本邦夫
    • Organizer
      日本癌学会
    • Place of Presentation
      名古屋国際会議場(愛知県名古屋市)
    • Year and Date
      2015-10-09
    • Data Source
      KAKENHI-PROJECT-15K14473
  • [Presentation] A RaPID way for the discovery of pseud-natural products and its innovation2015

    • Author(s)
      菅 裕明
    • Organizer
      Organic Chemistry Symposium(Royal Society of Chemistry Roadshow)
    • Place of Presentation
      東京大学 武田ホール(東京都文京区弥生)、日本
    • Year and Date
      2015-06-03
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26220204
  • [Presentation] Pseudo-Natural Product Synthesis and Drug Applications2014

    • Author(s)
      菅 裕明
    • Organizer
      International Conference on Medicinal Chemistry 2014
    • Place of Presentation
      Rouen's Law Faculty meeting room, Rouen, France
    • Year and Date
      2014-07-01
    • Invited
    • Data Source
      KAKENHI-PROJECT-26220204
  • [Presentation] 擬天然物の新機能創出分子技術2014

    • Author(s)
      Hiroaki Suga
    • Organizer
      日本化学会第94春期年会「社会持続的発展のための分子技術」
    • Place of Presentation
      名古屋大学東山キャンパス(名古屋市)
    • Year and Date
      2014-03-29
    • Invited
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Presentation] A novel drug discovery platform technology fro "Nontraditional" molecules2014

    • Author(s)
      菅 裕明
    • Organizer
      Pre-COST meeting “Innovation”
    • Place of Presentation
      Universita Degli Studi Firenze, Siena, Italy
    • Year and Date
      2014-06-25
    • Invited
    • Data Source
      KAKENHI-PROJECT-26220204
  • [Presentation] 特殊ペプチド創薬イノベーション2014

    • Author(s)
      菅 裕明
    • Organizer
      日本ケミカルバイオロジー学会第9回年会
    • Place of Presentation
      大阪大学 豊中キャンパス、日本
    • Year and Date
      2014-06-11
    • Invited
    • Data Source
      KAKENHI-PROJECT-26220204
  • [Presentation] A RaPID way to discover bioactive macrocyclic peptides2014

    • Author(s)
      菅 裕明
    • Organizer
      Cold Spring Harbor Asia "Synthetic Biology"
    • Place of Presentation
      Suzhou Dushu Lake Conference Center, Suzhou, China
    • Year and Date
      2014-12-04
    • Invited
    • Data Source
      KAKENHI-PROJECT-26220204
  • [Presentation] 特殊ペプチド創薬イノベーション2014

    • Author(s)
      菅 裕明
    • Organizer
      The Origin 2014
    • Place of Presentation
      奈良県新公会堂、日本
    • Year and Date
      2014-07-23
    • Invited
    • Data Source
      KAKENHI-PROJECT-26220204
  • [Presentation] Discovery of natural product-like petides accerelated by RaPID system2014

    • Author(s)
      Hiroaki Suga
    • Organizer
      AsiaTIDES, 2. Plenary Lecture
    • Place of Presentation
      シェラトン都ホテル東京(東京都港区)
    • Year and Date
      2014-02-25
    • Invited
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Presentation] A RaPID way to discover bioactive macrocyclic peptides2014

    • Author(s)
      菅 裕明
    • Organizer
      Asian Chemical Biology Symposium
    • Place of Presentation
      Education Resource Centre, Singapore
    • Year and Date
      2014-12-15
    • Invited
    • Data Source
      KAKENHI-PROJECT-26220204
  • [Presentation] Discovery of natural product-like petides accerelated by RaPID system2014

    • Author(s)
      菅 裕明
    • Organizer
      AsiaTIDES, 2.Plenary Lecture
    • Place of Presentation
      シェラトン都ホテル東京(東京都港区)(招待講演)
    • Year and Date
      2014-02-25
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Presentation] In Vitro Biophynthesis and Discovery of Pseudo-nutural Products2014

    • Author(s)
      菅 裕明
    • Organizer
      Chemical Biology meets Drug Discovery meeting, Royal Society of Chemistry
    • Place of Presentation
      Lilly Research Centre Erl Wood Manor, Surrey, UK
    • Year and Date
      2014-06-12
    • Invited
    • Data Source
      KAKENHI-PROJECT-26220204
  • [Presentation] 特殊ペプチド創薬イノベーション2014

    • Author(s)
      菅 裕明
    • Organizer
      第51回ペプチド討論会
    • Place of Presentation
      徳島大学大塚講堂、日本
    • Year and Date
      2014-10-22
    • Invited
    • Data Source
      KAKENHI-PROJECT-26220204
  • [Presentation] A RaPID way to discover bioactive macrocyclic Scafforld and its Innovation2014

    • Author(s)
      菅 裕明
    • Organizer
      Joint symposium of the Institute of Convergent Technology at Seoul National University and the Research Center for Advanced Science and Technology at the University of Tokyo
    • Place of Presentation
      Conference RoomI, AICT, Suwon, Korea
    • Year and Date
      2014-11-28
    • Invited
    • Data Source
      KAKENHI-PROJECT-26220204
  • [Presentation] 擬天然物の新機能創出分子技術2014

    • Author(s)
      菅 裕明
    • Organizer
      日本化学会第94春期年会「社会持続的発展のための分子技術」
    • Place of Presentation
      名古屋大学東山キャンパス(名古屋市)(招待講演)
    • Year and Date
      2014-03-29
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Presentation] A RaPID way to discover bioactive macrocyclic peptides2014

    • Author(s)
      菅 裕明
    • Organizer
      Switzerland-Japan Chemical Biology Symposium
    • Place of Presentation
      University of Bern, Switzerland
    • Year and Date
      2014-10-02
    • Invited
    • Data Source
      KAKENHI-PROJECT-26220204
  • [Presentation] Discovery of natural product-like petides accerelated by RaPID system2013

    • Author(s)
      菅 裕明
    • Organizer
      Basel Chemical Society Lectureship
    • Place of Presentation
      Medicinal Chemistry Navartis Institute (Basel, Switzerland)(招待講演)
    • Year and Date
      2013-10-24
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Presentation] Discovery of natural product-like petides accerelated by RaPID system2013

    • Author(s)
      Hiroaki Suga
    • Organizer
      Current Strategy for Delopment of Biopharmaceuticals and Small Molecule Drugs
    • Place of Presentation
      北海道大学(北海道札幌)
    • Invited
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Presentation] Discovery of natural product-like petides accerelated by RaPID system2013

    • Author(s)
      菅 裕明
    • Organizer
      American Peptide Symposium 2013
    • Place of Presentation
      Hilton Waikoloa Village (Hawaii, USA)(招待講演)
    • Year and Date
      2013-06-23
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Presentation] Discovery of natural product-like petides accerelated by RaPID system2013

    • Author(s)
      菅 裕明
    • Organizer
      RIKEN-Max Planc Joint Symposium
    • Place of Presentation
      理化学研究所和光研究所(埼玉県和光市)(招待講演)
    • Year and Date
      2013-04-16
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Presentation] Discovery of natural product-like petides accerelated by RaPID system2013

    • Author(s)
      Hiroaki Suga
    • Organizer
      Solvay Conference of "New Chemistry and New Opportunities from the Expanding Protein Universe"
    • Place of Presentation
      International Solvay Institute (Brussels, Belgium)
    • Invited
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Presentation] Discovery of natural product-like petides accerelated by RaPID system2013

    • Author(s)
      Hiroaki Suga
    • Organizer
      "Jokichi Takamine" 130 years of Glasgow-Japan Collaboration
    • Place of Presentation
      University of Glasgow (Glasgow, UK)
    • Invited
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Presentation] Discovery of natural product-like petides accerelated by RaPID system2013

    • Author(s)
      Hiroaki Suga
    • Organizer
      ACS National Meeting
    • Place of Presentation
      Indiana Convention Center (Indianapolis, USA)
    • Year and Date
      2013-09-09
    • Invited
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Presentation] Discovery of natural product-like petides accerelated by RaPID system2013

    • Author(s)
      菅 裕明
    • Organizer
      "Jokichi Takamine" 130 years of Glasgow-Japan Collaboration
    • Place of Presentation
      University of Glasgow (Glasgow, UK)(招待講演)
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Presentation] Discovery of natural product-like petides accerelated by RaPID system2013

    • Author(s)
      菅 裕明
    • Organizer
      Symposium on Foldamers
    • Place of Presentation
      Les Cordeliers Conference Centre(Paris, France)(招待講演)
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Presentation] Discovery of natural product-like petides accerelated by RaPID system2013

    • Author(s)
      Hiroaki Suga
    • Organizer
      RIKEN-Max Planc Joint Symposium
    • Place of Presentation
      理化学研究所和光研究所(埼玉県和光市)
    • Year and Date
      2013-04-16
    • Invited
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Presentation] Discovery of natural product-like petides accerelated by RaPID system2013

    • Author(s)
      菅 裕明
    • Organizer
      International Conference on Structural Genomics2013, Structural Life Science
    • Place of Presentation
      京王プラザホテル(北海道札幌)(招待講演)
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Presentation] Discovery of natural product-like petides accerelated by RaPID system2013

    • Author(s)
      Hiroaki Suga
    • Organizer
      Gordon Research Conference, Bioorganic Chemistry
    • Place of Presentation
      Proctor Academy (New Hampshire, USA)
    • Year and Date
      2013-06-13
    • Invited
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Presentation] The non-traditional peptide therapeutics2013

    • Author(s)
      菅 裕明
    • Organizer
      Discovery Chemistry Congress
    • Place of Presentation
      Munich, Germany
    • Invited
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Presentation] Discovery of natural product-like petides accerelated by RaPID system2013

    • Author(s)
      Hiroaki Suga
    • Organizer
      American Peptide Symposium 2013
    • Place of Presentation
      Hilton Waikoloa Village (Hawaii, USA)
    • Year and Date
      2013-06-23
    • Invited
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Presentation] Discovery of natural product-like petides accerelated by RaPID system2013

    • Author(s)
      Hiroaki Suga
    • Organizer
      Keynote Lecture, Symposium on Chemoselective Reactions for the Synthesis and Application
    • Place of Presentation
      Max Planc Institute (Dortmund, Germany)
    • Invited
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Presentation] Discovery of natural product-like petides accerelated by RaPID system2013

    • Author(s)
      Hiroaki Suga
    • Organizer
      Lilly Distinguished Lecturer at Colorado State University
    • Place of Presentation
      Colorado State University (Fort Collins, US)
    • Year and Date
      2013-09-10
    • Invited
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Presentation] Discovery of natural product-like petides accerelated by RaPID system2013

    • Author(s)
      菅 裕明
    • Organizer
      Gordon Research Conference, Bioorganic Chemistry
    • Place of Presentation
      Proctor Academy (New Hampshire, USA)(招待講演)
    • Year and Date
      2013-06-13
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Presentation] Discovery of natural product-like petides accerelated by RaPID system2013

    • Author(s)
      Hiroaki Suga
    • Organizer
      Basel Chemical Society Lectureship
    • Place of Presentation
      Medicinal Chemistry Navartis Institute (Basel, Switzerland)
    • Year and Date
      2013-10-24
    • Invited
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Presentation] Discovery of natural product-like petides accerelated by RaPID system2013

    • Author(s)
      Hiroaki Suga
    • Organizer
      Biochemistry Seminar of University of Colorado, BioFrontier Institute
    • Place of Presentation
      Univerity of Colorado (Boulder, USA)
    • Year and Date
      2013-09-11
    • Invited
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Presentation] Discovery of natural product-like petides accerelated by RaPID system2013

    • Author(s)
      菅 裕明
    • Organizer
      Keynote Lecture Symposium on Chemoselective Reactions for the Synthesis and Application
    • Place of Presentation
      Max Planc Institute (Dortmund, Germany)(招待講演)
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Presentation] Discovery of natural product-like petides accerelated by RaPID system2013

    • Author(s)
      菅 裕明
    • Organizer
      ACS National Meeting
    • Place of Presentation
      Indiana Convention Center (Indianapolis, USA)(招待講演)
    • Year and Date
      2013-09-09
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Presentation] Discovery of natural product-like petides accerelated by RaPID system2013

    • Author(s)
      Hiroaki Suga
    • Organizer
      International Conference on Structural Genomics 2013, Structural Life Science
    • Place of Presentation
      京王プラザホテル(北海道札幌)
    • Invited
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Presentation] Discovery of natural product-like petides accerelated by RaPID system2013

    • Author(s)
      菅 裕明
    • Organizer
      RiboClub
    • Place of Presentation
      Hotel Cheribourg (Quebec,Canada)(招待講演)
    • Year and Date
      2013-09-22
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Presentation] Discovery of natural product-like petides accerelated by RaPID system2013

    • Author(s)
      菅 裕明
    • Organizer
      Lilly Distinguished Lecturer at Colorado State University
    • Place of Presentation
      Colorado State University (Fort Collins, US)(招待講演)
    • Year and Date
      2013-09-10
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Presentation] Discovery of natural product-like petides accerelated by RaPID system2013

    • Author(s)
      菅 裕明
    • Organizer
      Korean Peptide Protein Society Meeting
    • Place of Presentation
      Seoul National University (Seoul, Korea)(招待講演)
    • Year and Date
      2013-11-29
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Presentation] Discovery of natural product-like petides accerelated by RaPID system2013

    • Author(s)
      Hiroaki Suga
    • Organizer
      Korean Peptide Protein Society Meeting
    • Place of Presentation
      Seoul National University (Seoul, Korea)
    • Year and Date
      2013-11-29
    • Invited
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Presentation] Discovery of natural product-like petides accerelated by RaPID system2013

    • Author(s)
      Hiroaki Suga
    • Organizer
      RiboClub
    • Place of Presentation
      Hotel Cheribourg (Quebec, Canada)
    • Year and Date
      2013-09-22
    • Invited
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Presentation] Discovery of natural product-like petides accerelated by RaPID system2013

    • Author(s)
      菅 裕明
    • Organizer
      Current Strategy for Development of Biopharmaceuticals and Small Molecule Drugs
    • Place of Presentation
      北海道大学(北海道札幌)(招待講演)
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Presentation] Discovery of natural product-like petides accerelated by RaPID system2013

    • Author(s)
      菅 裕明
    • Organizer
      Solvay Conference of "New Chemistry and New Opportunities from the Expanding Protein Universe"
    • Place of Presentation
      International Solvay Institute (Brussels, Belgium)(招待講演)
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Presentation] Discovery of natural product-like petides accerelated by RaPID system2013

    • Author(s)
      Hiroaki Suga
    • Organizer
      Symposium on Foldamers
    • Place of Presentation
      Les Cordeliers Conference Centre (Paris, France)
    • Invited
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Presentation] Discovery of natural product-like petides accerelated by RaPID system2013

    • Author(s)
      菅 裕明
    • Organizer
      Biochemistry Seminar of University of Colorado BioFrontier Institute
    • Place of Presentation
      Univerity of Colorado (Boulder, USA)(招待講演)
    • Year and Date
      2013-09-11
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Presentation] Discovery of natural product-like petides accerelated by RaPID system2013

    • Author(s)
      菅 裕明
    • Organizer
      5th Gratama Workshop
    • Place of Presentation
      東京工業大学大岡山キャンパス(東京都目黒区)(招待講演)
    • Year and Date
      2013-05-30
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Presentation] Discovery of natural product-like petides accerelated by RaPID system2013

    • Author(s)
      Hiroaki Suga
    • Organizer
      5th Gratama Workshop
    • Place of Presentation
      東京工業大学大岡山キャンパス(東京都目黒区)
    • Year and Date
      2013-05-30
    • Invited
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Presentation] The non-traditional peptide therapeutics2012

    • Author(s)
      菅 裕明
    • Organizer
      ICCP2012-International Conference on Circular Proteins
    • Place of Presentation
      Heron island, Australia
    • Invited
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Presentation] Genetic code reprogramming : Its concept and applications for drug discovery2012

    • Author(s)
      菅裕明
    • Organizer
      北海道大学GCQE国際会議
    • Place of Presentation
      札幌(招待講演)
    • Year and Date
      2012-02-22
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Presentation] 特殊ペプチドが起こす構造生命科学と創薬の飛躍2012

    • Author(s)
      菅裕明
    • Organizer
      学術会議公開シンポジウム「構造生命科学」
    • Place of Presentation
      東京(招待講演)
    • Year and Date
      2012-01-09
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Presentation] RaPID Discovery of Natural Product-Like Peptides against Therapeutic Targets2012

    • Author(s)
      菅 裕明
    • Organizer
      Asia TIDES Oligonucleotide and Peptide Research, Technology and Product Development
    • Place of Presentation
      Las Vegas, NV USA
    • Invited
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Presentation] The non-traditional peptide therapeutics2012

    • Author(s)
      菅 裕明
    • Organizer
      13th Tetrahedron Symposium
    • Place of Presentation
      Taipei, Taiwan
    • Invited
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Presentation] RaPID system: A new discovery tool of natural product-like peptides from de novo libraries2012

    • Author(s)
      菅 裕明
    • Organizer
      3rd International Symposium on DNA-encoded chemical libraries
    • Place of Presentation
      Zurich, Switzerland
    • Invited
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Presentation] Flexizyme, FIT and RaPID: The enabling technologies for probes discovery2012

    • Author(s)
      菅 裕明
    • Organizer
      XXIV tRNA Conference
    • Place of Presentation
      Olmue, Chile
    • Invited
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Presentation] Non-Traditional Peptide Therapeutic Leads2012

    • Author(s)
      菅 裕明
    • Organizer
      Gordon Research Conference Medicinal Chemistry
    • Place of Presentation
      Colby-Sawyer College New London, NH USA
    • Invited
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Presentation] The non-traditional peptide therapeutics2012

    • Author(s)
      菅 裕明
    • Organizer
      EFMC-ISMC 2012 22nd International Symposium on Medicinal Chemistry
    • Place of Presentation
      Berlin, Germany
    • Invited
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Presentation] The non-traditional peptide therapeutics2012

    • Author(s)
      菅 裕明
    • Organizer
      13th FAOBMB International Congress of Biochemistry and Molecular Biology
    • Place of Presentation
      Bangkok, Thailand
    • Invited
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Presentation] Genetic code reprogramming : Its concept and applications for drug discovery2011

    • Author(s)
      菅裕明
    • Organizer
      The 11th Tetrahedron Symposium "Frontiers in Organic and Bioorganic Chemistry"
    • Place of Presentation
      Sitges, Barcelona, Spain(招待講演)
    • Year and Date
      2011-06-22
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Presentation] Genetic code reprogramming : Its concept and applications for drug discovery2011

    • Author(s)
      菅裕明
    • Organizer
      European Protein Society Meeting
    • Place of Presentation
      Stockholm, Sweden(招待講演)
    • Year and Date
      2011-05-25
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Presentation] Genetic code reprogramming : Its concept and applications for drug discovery2011

    • Author(s)
      菅裕明
    • Organizer
      The 2011 International Symposium on Aminoacyl-tRNA synthetases
    • Place of Presentation
      Snowbird, Salt Lake City, USA(招待講演)
    • Year and Date
      2011-09-28
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Presentation] Genetic code reprogramming : Its concept and applications for drug discovery2011

    • Author(s)
      菅裕明
    • Organizer
      5th International Symposium on Advancing the Chemical Sciences on Challenges in Chemical Biology
    • Place of Presentation
      Manchester, UK(招待講演)
    • Year and Date
      2011-07-27
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Presentation] Genetic code reprogramming : Its concept and applications for drug discovery2011

    • Author(s)
      菅裕明
    • Organizer
      PepTalk, Cambrige Health Institute
    • Place of Presentation
      Boston, Massachusetts, USA(招待講演)
    • Year and Date
      2011-05-10
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Presentation] Genetic code reprogramming for the discovery of a novel class of peptide drug leads2011

    • Author(s)
      菅裕明
    • Organizer
      22^<nd> Enzyme Mechanisms Conference
    • Place of Presentation
      St.Pete beach FL, USA
    • Year and Date
      2011-01-04
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Presentation] Genetic code reprogramming for the discovery of a novel class of peptide, drug leads2011

    • Author(s)
      菅裕明
    • Organizer
      Royal Society discussion meeting : Chemical Origins and Early Evolution
    • Place of Presentation
      London, UK
    • Year and Date
      2011-02-21
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Presentation] Genetic code reprogramming : Its concept and applications for drug discovery2011

    • Author(s)
      菅裕明
    • Organizer
      The 9th Australian Peptide Conference
    • Place of Presentation
      Hamilton Island, Australia(招待講演)
    • Year and Date
      2011-10-18
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Presentation] Genetic code reprogramming : Its concept and applications for drug discovery2011

    • Author(s)
      菅裕明
    • Organizer
      細胞を創る会
    • Place of Presentation
      大阪(招待講演)
    • Year and Date
      2011-10-28
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Presentation] Genetic code reprogramming : Its concept and applications for drug discovery2011

    • Author(s)
      菅裕明
    • Organizer
      The 22nd American Peptide Symposium
    • Place of Presentation
      San Diego, USA(招待講演)
    • Year and Date
      2011-06-27
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Presentation] Genetic code reprogramming : Its concept and applications for drug discovery2011

    • Author(s)
      菅裕明
    • Organizer
      AsiaTIDES : Oligonucleotide and Peptide Research, Technology and Product Development
    • Place of Presentation
      Tokyo, Japan(招待講演)
    • Year and Date
      2011-02-28
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Presentation] Genetic code reprogramming : Its concept and applications for drug discovery2011

    • Author(s)
      菅裕明
    • Organizer
      日本分子生物学会年会「Leading Edge seminar」
    • Place of Presentation
      横浜(招待講演)
    • Year and Date
      2011-11-13
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Presentation] Genetic code reprogramming : Its concept and applications for drug discovery2011

    • Author(s)
      菅裕明
    • Organizer
      International RNA Society Meeting
    • Place of Presentation
      Kyoto, Japan(招待講演)
    • Year and Date
      2011-06-16
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Presentation] Genetic code reprogramming : Its concept and applications for drug discovery2011

    • Author(s)
      菅裕明
    • Organizer
      The 38th International Symposium of Nucleic Acid Chemistry
    • Place of Presentation
      Sapporo, Hokkaido, Japan(招待講演)
    • Year and Date
      2011-11-11
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Presentation] Genetic code reprogramming : Its concept and applications for drug discovery2011

    • Author(s)
      菅裕明
    • Organizer
      名古屋大学GCOE国際会議
    • Place of Presentation
      名古屋(招待講演)
    • Year and Date
      2011-11-30
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Presentation] 特殊ペプチド創薬2010

    • Author(s)
      菅裕明
    • Organizer
      日本生物物理学会年会
    • Place of Presentation
      仙台、東北大学
    • Year and Date
      2010-09-20
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Presentation] Genetic code reprogramming for the discovery of a novel class of peptide drug lead2010

    • Author(s)
      菅裕明
    • Organizer
      RIKEN Chemical Biology Symposium
    • Place of Presentation
      和光、理研 和光研究所
    • Year and Date
      2010-10-29
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Presentation] 特殊ペプチド創薬2010

    • Author(s)
      菅裕明
    • Organizer
      第29回メディシナルケミストリーシンポジウム
    • Place of Presentation
      京都、京都テレサホール
    • Year and Date
      2010-11-18
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Presentation] Genetic Code reprogramming and its application for the discovery of a new class of peptide drugs2010

    • Author(s)
      菅裕明
    • Organizer
      The 75^<th> Israel Chemical Society Meeting, Israel
    • Place of Presentation
      Tel Aviv, Israel
    • Year and Date
      2010-01-29
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Presentation] 特殊ペプチド創薬2010

    • Author(s)
      菅裕明
    • Organizer
      仙台万有シンポジウム
    • Place of Presentation
      仙台、仙台国際センター
    • Year and Date
      2010-06-05
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Presentation] Genetic code reprogramming for the discovery of a novel class of peptide drug lead2010

    • Author(s)
      菅裕明
    • Organizer
      5^<th> International Peptide Symposium
    • Place of Presentation
      京都、京都国際コンファレンスセンター
    • Year and Date
      2010-12-08
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Presentation] Genetic code reprogramming for the discovery of a novel class of peptide drug lead2010

    • Author(s)
      菅裕明
    • Organizer
      The 2010 Annual Meeting of the American Society for Biochemistry and Molecular Biology
    • Place of Presentation
      Los Angels, California, USA
    • Year and Date
      2010-04-27
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Presentation] Genetic Code reprogramming and its application for the discovery of a new class of peptide drugs2010

    • Author(s)
      菅裕明
    • Organizer
      AsiaTide
    • Place of Presentation
      東京
    • Year and Date
      2010-02-23
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Presentation] 特殊ペプチド創薬2010

    • Author(s)
      菅裕明
    • Organizer
      日本RNA学会年会
    • Place of Presentation
      東京、一橋記念講堂
    • Year and Date
      2010-07-07
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Presentation] Genetic Code reprogramming and its application for the discovery of a new class of peptide drugs2010

    • Author(s)
      菅裕明
    • Organizer
      2010 Chemistry & Biology of Peptides Gordon Research Conference
    • Place of Presentation
      Ventura, USA
    • Year and Date
      2010-03-01
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Presentation] 特殊ペプチド創薬2010

    • Author(s)
      菅裕明
    • Organizer
      日本化学会年会、ATPプログラム
    • Place of Presentation
      大阪
    • Year and Date
      2010-03-27
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Presentation] Genetic code reprogramming for the discovery of a novel class of peptide drug leads2010

    • Author(s)
      菅裕明
    • Organizer
      PacifiChem 2010
    • Place of Presentation
      Honolulu, Hawaii, USA
    • Year and Date
      2010-12-18
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Presentation] Genetic code reprogramming for the discovery of a novel class of peptide drug lead2010

    • Author(s)
      菅裕明
    • Organizer
      Yale University, Symposium of Chemical Biology
    • Place of Presentation
      Connecticut, USA
    • Year and Date
      2010-05-14
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Presentation] Genetic code reprogramming for the discovery of a novel class of peptide drug lead2010

    • Author(s)
      菅裕明
    • Organizer
      国際構造エピゲノムシンポジウム
    • Place of Presentation
      横浜、理研 横浜研究所
    • Year and Date
      2010-10-01
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Presentation] Genetic Code reprogramming and its application for the discovery of a new class of peptide drugs2009

    • Author(s)
      菅裕明
    • Organizer
      The 1^<st> International Conference for Circular Protein
    • Place of Presentation
      Heron Island, Australia
    • Year and Date
      2009-10-16
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Presentation] Genetic Code reprogramming and its application for the discovery of a new class of peptide drugs2009

    • Author(s)
      菅裕明
    • Organizer
      The 3rd Asia-Pacific International Peptide Symposium
    • Place of Presentation
      Jeju Island, Korea
    • Year and Date
      2009-11-09
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Presentation] Genetic Code reprogramming and its application for the discovery of a new class of peptide drugs2009

    • Author(s)
      菅裕明
    • Organizer
      Naito Foundation Conference in Chemical Biology
    • Place of Presentation
      札幌
    • Year and Date
      2009-09-08
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Presentation] 特殊ペプチドの翻訳合成:創薬への展開2009

    • Author(s)
      菅裕明
    • Organizer
      日本化学会
    • Place of Presentation
      西船橋・日大キャンパス
    • Year and Date
      2009-03-27
    • Data Source
      KAKENHI-PROJECT-16101007
  • [Presentation] ETH Zurich2009

    • Author(s)
      菅
    • Organizer
      Institute of Organic Chemistry Seminar
    • Place of Presentation
      Zurich, Switzerland
    • Year and Date
      2009-01-08
    • Data Source
      KAKENHI-PROJECT-16101007
  • [Presentation] 第2次先端ウオッチング-生合成化学2009

    • Author(s)
      菅
    • Organizer
      日本化学会年会
    • Place of Presentation
      西船橋
    • Year and Date
      2009-03-27
    • Data Source
      KAKENHI-PROJECT-16101007
  • [Presentation] Genetic Code reprogramming and its application for the discovery of a new class of peptide drugs2009

    • Author(s)
      菅裕明
    • Organizer
      Burugenstock Conference
    • Place of Presentation
      Lucerne, Switzerland
    • Year and Date
      2009-05-17
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Presentation] Genetic code reprogramming : A new emerging technology for the discovery of non-standard peptidic drugs2009

    • Author(s)
      菅裕明
    • Organizer
      Burgenstock Conference
    • Place of Presentation
      Lucerne, Switzerland
    • Year and Date
      2009-05-24
    • Data Source
      KAKENHI-PROJECT-21241051
  • [Presentation] Genetic Code reprogramming and its application for the discovery of a new class of peptide drugs2009

    • Author(s)
      菅裕明
    • Organizer
      Peptide Engineering : Therapeutic Peptide" Fifth Peptide Engineering Meeting
    • Place of Presentation
      Barcelona, Spain
    • Year and Date
      2009-10-26
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Presentation] Genetic Code reprogramming and its application for the discovery of a new class of peptide drugs2009

    • Author(s)
      菅裕明
    • Organizer
      第5回日韓天然物化学談話会
    • Place of Presentation
      湯河原
    • Year and Date
      2009-08-28
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Presentation] 特殊ペプチド創薬2009

    • Author(s)
      菅裕明
    • Organizer
      日本発生学会年会
    • Place of Presentation
      三島
    • Year and Date
      2009-11-27
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Presentation] Genetic Code reprogramming and its application for the discovery of a new class of peptide drugs2009

    • Author(s)
      菅裕明
    • Organizer
      Nottingham 'New Horizons' meeting 2009
    • Place of Presentation
      Nottingham, UK
    • Year and Date
      2009-11-04
    • Data Source
      KAKENHI-PROJECT-21000005
  • [Presentation] International Symposium on Molecular Recognition of DNA2008

    • Author(s)
      菅
    • Organizer
      Biological Applications
    • Place of Presentation
      東京
    • Year and Date
      2008-09-16
    • Data Source
      KAKENHI-PROJECT-16101007
  • [Presentation] 特殊ペプチドの翻訳合成:創薬への展開2008

    • Author(s)
      菅裕明
    • Organizer
      日本ケミカルバイオロジー研究会シンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2008-05-19
    • Data Source
      KAKENHI-PROJECT-16101007
  • [Presentation] of Methods in Protein Structural Analysis2008

    • Author(s)
      菅
    • Organizer
      The 17th Meeting
    • Place of Presentation
      札幌
    • Year and Date
      2008-08-28
    • Data Source
      KAKENHI-PROJECT-16101007
  • [Presentation] Chemical Biology of non-standard peptides2008

    • Author(s)
      菅裕明
    • Organizer
      RIKEN Conference in Chemical Biology
    • Place of Presentation
      成田
    • Year and Date
      2008-11-12
    • Data Source
      KAKENHI-PROJECT-16101007
  • [Presentation]2008

    • Author(s)
      菅
    • Organizer
      第7回新規素材探索研究会セミナー
    • Place of Presentation
      横浜
    • Year and Date
      2008-06-06
    • Data Source
      KAKENHI-PROJECT-16101007
  • [Presentation]2008

    • Author(s)
      菅
    • Organizer
      日本ケミカルバイオロジー研究会シンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2008-05-19
    • Data Source
      KAKENHI-PROJECT-16101007
  • [Presentation]2008

    • Author(s)
      菅
    • Organizer
      前期有機合成化学講習会
    • Place of Presentation
      東京
    • Year and Date
      2008-06-18
    • Data Source
      KAKENHI-PROJECT-16101007
  • [Presentation]2008

    • Author(s)
      菅
    • Organizer
      第128回日本薬学会年会・特別講演
    • Place of Presentation
      横浜
    • Year and Date
      2008-03-28
    • Data Source
      KAKENHI-PROJECT-16101007
  • [Presentation]2008

    • Author(s)
      菅
    • Organizer
      BioJapan
    • Place of Presentation
      横浜
    • Year and Date
      2008-10-16
    • Data Source
      KAKENHI-PROJECT-16101007
  • [Presentation] Veyrier du Lac2008

    • Author(s)
      菅
    • Organizer
      Aminoacyl-tRNA Synthetase Meeting 2008
    • Place of Presentation
      France
    • Year and Date
      2008-09-11
    • Data Source
      KAKENHI-PROJECT-16101007
  • [Presentation] Japanese-German Frontier of Science2008

    • Author(s)
      菅
    • Organizer
      Heidelberg
    • Place of Presentation
      Germany
    • Year and Date
      2008-10-30
    • Data Source
      KAKENHI-PROJECT-16101007
  • [Presentation] RIKEN Conference2008

    • Author(s)
      菅
    • Organizer
      Chemical Biology
    • Place of Presentation
      成田
    • Year and Date
      2008-11-12
    • Data Source
      KAKENHI-PROJECT-16101007
  • [Presentation]2008

    • Author(s)
      菅
    • Organizer
      第56回日本化学療法学会総会
    • Place of Presentation
      岡山
    • Year and Date
      2008-06-17
    • Data Source
      KAKENHI-PROJECT-16101007
  • [Presentation] ‘Discovering protease inhibitors: Using genetic code reprogramming to generate macrocyclic peptides’

    • Author(s)
      Joseph Rogers, Ikou Shoji, Hiroaki Suga
    • Organizer
      Lorne conference on protein structure and function
    • Place of Presentation
      Lorne, Australia
    • Year and Date
      2015-02-08 – 2015-02-12
    • Data Source
      KAKENHI-PROJECT-13F03766
  • [Presentation] 亜型を超えた感染阻害活性を示すヘマグルチニン結合性特殊環状ペプチド

    • Author(s)
      斉藤 誠、安井文彦、棟方 翼、飛田良美、小澤 真、小原恭子、伊東利紗、菅 裕明、佐々木 亨、窪田規一、小原道法
    • Organizer
      第62回日本ウイルス学会学術集会
    • Place of Presentation
      パシフィコ横浜(神奈川)
    • Year and Date
      2014-11-10 – 2014-11-12
    • Data Source
      KAKENHI-PROJECT-25670224
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  • 2.  KUMON Hiromi (30144760)
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  • 3.  MONDEN Koichi (60291473)
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    # of Collaborated Projects: 3 results
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  • 5.  ROGERS JOSEPH
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 6 results
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    # of Collaborated Projects: 2 results
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    # of Collaborated Projects: 2 results
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  • 8.  WATANABE Toyohiko (30432644)
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    # of Collaborated Projects: 1 results
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    # of Collaborated Projects: 1 results
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    # of Collaborated Projects: 1 results
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    # of Collaborated Projects: 1 results
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    # of Collaborated Projects: 1 results
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  • 80.  ZHANG YUE
    # of Collaborated Projects: 1 results
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  • 81.  LEE KANG JU
    # of Collaborated Projects: 1 results
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    # of Collaborated Projects: 1 results
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    # of Collaborated Projects: 1 results
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  • 87.  TAKAYUKI Katoh
    # of Collaborated Projects: 0 results
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  • 89.  NATSUME Tohru
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  • 90.  内田 毅
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  • 91.  加部 泰明
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  • 92.  高木 淳一
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  • 93.  渡邉 瑞貴
    # of Collaborated Projects: 0 results
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  • 94.  寺坂 尚紘
    # of Collaborated Projects: 0 results
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  • 95.  松森 信明
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  • 98.  浜田 恵輔
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  • 99.  HIPOLITO CHRISTOPHER
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 4 results
  • 100.  パシオラ トビー
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
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