TANIGUCHI YOSUKE 谷口陽祐

… Alternative Names

TANIGUCHI Yosuke 谷口陽祐

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Researcher Number	00452714
Other IDs	https://orcid.org/0000-0002-8985-3629
Affiliation (Current)	2025: 岡山大学, 医歯薬学域, 教授
Affiliation (based on the past Project Information) *help	2024: 岡山大学, 医歯薬学域, 教授 2016 – 2023: 九州大学, 薬学研究院, 准教授 2017: 九州大学, 大学院薬学研究院, 准教授 2013 – 2015: 九州大学, 薬学研究科(研究院), 准教授 2012: 九州大学, 薬学研究科(研究院), 助教 … More 2012: 九州大学, 薬学研究院, 助教 2007 – 2009: 九州大学, 大学院・薬学研究院, 助教 2008: 九大, 薬学研究科(研究院), 助教 2007 – 2008: Kyushu University, 薬学研究院, 助教 Less
Review Section/Research Field	Principal Investigator Drug development chemistry / Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related / Chemical pharmacy / Sections That Are Subject to Joint Review: Basic Section47010:Pharmaceutical chemistry and drug development sciences-related , Basic Section47050:Environmental and natural pharmaceutical resources-related / Basic Section 47050:Environmental and natural pharmaceutical resources-related / Pharmaceutical Sciences and related fields Except Principal Investigator Chemical pharmacy / Medium-sized Section 90:Biomedical engineering and related fields
Keywords	Principal Investigator 人工核酸 / 核酸医薬 / ゲノム創薬 / 3本鎖DNA / 核酸化学 / アンチジーン核酸 / 分子認識 / アンチジーン / 核送達技術 / 創薬化学 … More / 酸化損傷塩基 / 機能融合 / 機能性人工核酸 / マルチコンジュゲート / 遺伝子発現抑制 / 遺伝子修復 / 遺伝子発現活性化 / 遺伝子発現阻害 / エピジェネティック制御 / 核内移行 / 位置特定法 / 人工核酸トリリン酸体 / オキソグアノシン / 槽副反応 / 増幅反応 / DNA合成酵素 / 核酸 / 非天然型3本鎖DNA / アンチジーン法 / 創薬 / 薬学 / ジヌクレオチドユニット / CpGアイランド / 核酸誘導体 / 有機化学 / ３本鎖DNA形成オリゴヌクレオチド / 3本鎖形成オリゴヌクレオチド / 遺伝子発現制御 / oxorG / 8-oxo-rG / 認識分子 / 遺伝子検出 / W-字型人工核酸 / ミスマッチサイト / W字型人工核酸 / ビシクロ型人工核酸 … More Except Principal Investigator 有機化学 / ナノ医薬 / 機能性核酸 / アンチジーン核酸 / 生体適合性高分子 / 核酸医薬デリバリー / 脳疾患 / 核酸デリバリー / 核酸医薬 / 薬物送達システム / 官能基転移反応 / 官能基転移 / 選択的化学修飾 / 分子認識 / 核酸 / 薬学 / 部位特異的RNA修飾 / オリゴヌクレオチド / 人工核酸 / DNA / RNA / 遺伝子発現制御 / 3本鎖DNA / アンチジーン / アンチセンス / マイナーグループバインダー / インテリジェント人工核酸 / インテリジェント / インテリジェント核酸 / 反応性分子 / ゲノム標的分子 Less

3本鎖DNA形成を基軸とした人工核酸の開発と遺伝子発現コントロール技術への新展開Principal Investigator
- Principal Investigator
  
  谷口陽祐
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
  Basic Section 47050:Environmental and natural pharmaceutical resources-related
  Sections That Are Subject to Joint Review: Basic Section47010:Pharmaceutical chemistry and drug development sciences-related , Basic Section47050:Environmental and natural pharmaceutical resources-related
- Research Institution
  Okayama University
  Kyushu University
Development of advanced nanomedicines for brain-targeted oligonucleotide delivery
- Principal Investigator
  
  Miyata Kanjiro
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  The University of Tokyo
Development of artificial nucleoside analogues for the duplex DNA recognition, and antigene oligonucleotidesPrincipal Investigator
- Principal Investigator
  
  Taniguchi Yosuke
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
- Research Institution
  Kyushu University
Development of novel gene detection method using artificial nucleic acid capable of recognizing damaged basesPrincipal Investigator
- Principal Investigator
  
  Taniguchi Yosuke
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  Pharmaceutical Sciences and related fields
- Research Institution
  Kyushu University
Examination of oligonucleotide therapeutics based on the triplex DNA formation by artificial oligonucleotidePrincipal Investigator
- Principal Investigator
  
  Taniguchi Yosuke
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Drug development chemistry
- Research Institution
  Kyushu University
Chemically reactive oligonucleotides for site-specific modification of RNA and artificial RNA editing
- Principal Investigator
  
  Sasaki Shigeki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kyushu University
Development of CpG island binding molecule based on artificial dinucleotidePrincipal Investigator
- Principal Investigator
  
  Taniguchi Yosuke
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Drug development chemistry
- Research Institution
  Kyushu University
Development of the recognition molecule for 8-oxo-rG in RNAPrincipal Investigator
- Principal Investigator
  
  TANIGUCHI YOSUKE
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Drug development chemistry
- Research Institution
  Kyushu University
Development of antigene strategy by triplex forming oligonucleotides having artificial nucleoside analoguesPrincipal Investigator
- Principal Investigator
  
  TANIGUCHI YOSUKE
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Drug development chemistry
- Research Institution
  Kyushu University
Development of the nucleoside analogs to harmonize with in vivo molecular functionPrincipal Investigator
- Principal Investigator
  
  TANIGUCHI Yosuke
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kyushu University
タンパク質との機能融合を目指したゲノム標的機能性人工核酸の開発Principal Investigator
- Principal Investigator
  
  谷口陽祐
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (Start-up)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kyushu University
Development of Genome-Targeting Molecules with Ability of Chemical Reactivity and Application to Intelligent Nano-Medicine
- Principal Investigator
  
  SASAKI Shigeki
- Project Period (FY)
  2005 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kyushu University

[Book] 核酸医薬・mRNA医薬の製造分析の基礎と基盤技術開発2023
- Author(s)
  谷口陽祐　他（監修：小比賀聡・井上貴雄）
- Total Pages
  290
- Publisher
  （株）シーエムシー・リサーチ
- ISBN
  9784910581347
- Data Source
  KAKENHI-PROJECT-19H03351
[Book] Synthesis of Therapeutic Oligonucleotides2018
- Author(s)
  Yosuke Taniguchi and Shigeki Sasaki
- Total Pages
  284
- Publisher
  Springer
- ISBN
  9789811319112
- Data Source
  KAKENHI-PROJECT-16H05100
[Journal Article] Development of an Artificial Nucleic Acid Skeleton Allowing for Unnatural-Type Triplex DNA Formation with Duplex DNA Having a TA Inversion Site2024
- Author(s)
  Ito Akihiro、Wang Lei、Notomi Ryotaro、Sasaki Shigeki、Taniguchi Yosuke
- Journal Title
  
  Chemical and Pharmaceutical Bulletin
  
  Volume: 72 Issue: 1 Pages: 16-20
- DOI
  10.1248/cpb.c23-00666
- ISSN
  0009-2363, 1347-5223
- Year and Date
  2024-01-01
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K27301
[Journal Article] Site-Specific Tritium Labeling at the Predefined Internal Position of the Chemically-Modified RNA2023
- Author(s)
  Murase Hirotaka、Lee Jeongsu、Taniguchi Yosuke、Sasaki Shigeki
- Journal Title
  
  Chemical and Pharmaceutical Bulletin
  
  Volume: 71 Issue: 1 Pages: 64-69
- DOI
  10.1248/cpb.c22-00738
- ISSN
  0009-2363, 1347-5223
- Year and Date
  2023-01-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K15398, KAKENHI-PROJECT-23K27301
[Journal Article] Inhibition of transcription and antiproliferative effects in a cancer cell line using antigene oligonucleotides containing artificial nucleoside analogues2023
- Author(s)
  Wang Lei、Notomi Ryotaro、Sasaki Shigeki、Taniguchi Yosuke
- Journal Title
  
  RSC Medicinal Chemistry
  
  Volume: 14 Issue: 8 Pages: 1482-1491
- DOI
  10.1039/d3md00139c
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21354, KAKENHI-PROJECT-23K27301
[Journal Article] Recognition of 5-Methyl-CG and CG Base Pairs in Duplex DNA with High Stability using Antiparallel-type Triplex-forming Oligonucleotides with 2-Guanidinoethyl-2'-deoxy-nebularine2022
- Author(s)
  Notomi R., Sasaki S. and Taniguchi Y.
- Journal Title
  
  Nucleic Acids Res
  
  Volume: 50 Issue: 21 Pages: 12071-12081
- DOI
  10.1093/nar/gkac1110
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03351
[Journal Article] Development of Artificial Nucleoside Analogues for the Recognition and Detection of Damaged Nucleoside in DNA2022
- Author(s)
  Taniguchi Y.
- Journal Title
  
  Journal of Synthetic Organic Chemistry, Japan
  
  Volume: 80 Issue: 1 Pages: 46-54
- DOI
  10.5059/yukigoseikyokaishi.80.46
- NAID
  130008141134
- ISSN
  0037-9980, 1883-6526
- Year and Date
  2022-01-01
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03351
[Journal Article] Selective Unnatural Base Pairing and Recognition of 2-Hydroxy-2'-deoxyadenosine in DNA by Pseudo-dC Derivatives2022
- Author(s)
  Miyahara R. and Taniguchi Y.
- Journal Title
  
  J. Am. Chem. Soc.
  
  Volume: 144 Issue: 35 Pages: 16150-16156
- DOI
  10.1021/jacs.2c07000
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03351
[Journal Article] Multiple-turnover single nucleotide primer extension reactions to detect of 8-oxo-2'-deoxyguanosine2022
- Author(s)
  Kikukawa Y., Kawazoe R., Miyahara R., Sakurada T., Nagata Y., Sasaki S. andTaniguchi Y.
- Journal Title
  
  ChemComm
  
  Volume: 58 Issue: 35 Pages: 5399-5402
- DOI
  10.1039/d2cc01372j
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03351
[Journal Article] Application of the Functionality Transfer Oligodeoxynucleotide for the Site-Selective Modification of RNA with a Divers Molecule2022
- Author(s)
  Togo N., Murase H., Lee J., Taniguchi Y. and Sasaki S.
- Journal Title
  
  Chemical and Pharmaceutical Bulletin
  
  Volume: 70 Issue: 7 Pages: 498-504
- DOI
  10.1248/cpb.c22-00288
- ISSN
  0009-2363, 1347-5223
- Year and Date
  2022-07-01
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03351, KAKENHI-PROJECT-20K15398
[Journal Article] Implications of N7-hydrogen and C8-keto on the base pairing, mutagenic potential and repair of 8-oxo-2'-deoxy-adenosine:Investigation by nucleotide analogues2022
- Author(s)
  Wu J., Zhang M., Song L., Tan Y., Taniguchi Y., Hipolito C. J., Zhang Y. and Yin Y.
- Journal Title
  
  Bioorg. Chem.
  
  Volume: 127 Pages: 106029-106029
- DOI
  10.1016/j.bioorg.2022.106029
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03351
[Journal Article] Simple and Easy Synthesis of γ-Amido-dNTPs in Water and Their Polymerase Reaction Properties2021
- Author(s)
  Sakurada T., Miyahara R., Kawazoe R., Nagata Y., Kikukawa Y., Sasaki S. and Taniguchi Y.*
- Journal Title
  
  Chemical and Pharmaceutical Bulletin
  
  Volume: 69 Issue: 11 Pages: 1061-1066
- DOI
  10.1248/cpb.c21-00497
- NAID
  130008109895
- ISSN
  0009-2363, 1347-5223
- Year and Date
  2021-11-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03351
[Journal Article] Detection and structural analysis of pyrimidine-derived radicals generated on DNA using a profluorescent nitroxide probe.2021
- Author(s)
  Yamauchi K, Matsuoka Y, Takahashi M, Izumi Y, Taniguchi Y, Kawai K, Bamba T, Yamada KI*.
- Journal Title
  
  Chem. Commun.
  
  Volume: 58(1) Issue: 1 Pages: 56-59
- DOI
  10.1039/d1cc04998d
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K05167, KAKENHI-PLANNED-17H06304, KAKENHI-PROJECT-21K15240, KAKENHI-PROJECT-19H03351, KAKENHI-PROJECT-20K15101
[Journal Article] Design and synthesis of purine nucleoside analogues for the formation of stable anti-parallel-type triplex DNA with duplex DNA bearing the 5mCG base pair2021
- Author(s)
  Notomi R., Wang L., Sasaki S. and Taniguchi Y.*
- Journal Title
  
  RSC Adv.
  
  Volume: 11 Issue: 35 Pages: 21390-21396
- DOI
  10.1039/d1ra02831f
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03351
[Journal Article] Development of MTH1-Binding Nucleotide Analogs Based on 7,8-Dihalogenated 7-Deaza-dG Derivatives2021
- Author(s)
  Shi Hui、Ishikawa Ren、Heh Choon Han、Sasaki Shigeki、Taniguchi Yosuke
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 3 Pages: 1274-1274
- DOI
  10.3390/ijms22031274
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02558, KAKENHI-PROJECT-19H03351
[Journal Article] Enhancements in the utilization of antigene oligonucleotides in the nucleus by booster oligonucleotides2020
- Author(s)
  Wang Lei、Okamura Hidenori、Sasaki Shigeki、Taniguchi Yosuke
- Journal Title
  
  Chemical Communications
  
  Volume: 56 Issue: 67 Pages: 9731-9734
- DOI
  10.1039/d0cc04240d
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02558, KAKENHI-PROJECT-19H03351
[Journal Article] Oxidative-stress-driven in vivo mutagenesis induced by oral administration of potassium bromate in the small intestines of gpt delta mice2020
- Author(s)
  Aoki Y, Taniguchi Y, Matsumoto M, Matsumoto M, Ohno M, Masumura K, Sasaki S, Tsuzuki T, Yamamoto M, Nohmi T
- Journal Title
  
  Mutation Reseaｒch
  
  Volume: 850-851 Pages: 503136-503136
- DOI
  10.1016/j.mrgentox.2020.503136
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K12347, KAKENHI-PROJECT-17K19494, KAKENHI-PROJECT-20H03254
[Journal Article] Development of novel C-nucleoside analogues for the formation of antiparallel-type triplex DNA with duplex DNA that includes TA and dUA base pairs2020
- Author(s)
  Taniguchi Yosuke、Magata Yuya、Osuki Takayuki、Notomi Ryotaro、Wang Lei、Okamura Hidenori、Sasaki Shigeki
- Journal Title
  
  Organic & Biomolecular Chemistry
  
  Volume: 18 Issue: 15 Pages: 2845-2851
- DOI
  10.1039/d0ob00420k
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02558, KAKENHI-PROJECT-19H03351
[Journal Article] Synthesis of C-nucleoside analogues based on the pyrimidine skeleton for the formation of anti-parallel-type triplex DNA with a CG mismatch site2020
- Author(s)
  Notomi Ryotaro、Wang Lei、Osuki Takayuki、Okamura Hidenori、Sasaki Shigeki、Taniguchi Yosuke
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 28 Issue: 23 Pages: 115782-115782
- DOI
  10.1016/j.bmc.2020.115782
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02558, KAKENHI-PROJECT-19H03351
[Journal Article] Synthesis of γ-N-modified 8-oxo-2’-deoxyguanosine triphosphate and its characterization2019
- Author(s)
  Ninticha Thavoncharoensuba, Kento Maruyama, Choon Han Heh, Kok Hoong Leong, Hui Shi, Yoshiharu Shigematsu, Shigeki Sasaki, and Yosuke Taniguchi
- Journal Title
  
  NUCLEOSIDES, NUCLEOTIDES AND NUCLEIC ACIDS
  
  Volume: 印刷中 Issue: 8 Pages: 578-589
- DOI
  10.1080/15257770.2019.1586919
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19494, KAKENHI-PROJECT-16H05100
[Journal Article] Synthesis of 2'-deoxy-4-aminopyridinylpseudocytidine Derivatives for Incorporation Into Triplex Forming Oligonucleotides2019
- Author(s)
  Yosuke Taniguchi, Lei Wang, Hidenori Okamura, and Shigeki Sasaki
- Journal Title
  
  Current Protocols in Nucleic Acid Chemistry
  
  Volume: 印刷中 Issue: 1
- DOI
  10.1002/cpnc.80
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05100, KAKENHI-PROJECT-19H03351
[Journal Article] Effects of the 2-Substituted Adenosine-1,3-diazaphenoxazine 5′-Triphosphate Derivatives on the Single Nucleotide Primer Extension Reaction by DNA Polymerase2019
- Author(s)
  Taniguchi Y., Sagara I., Nagata Y., Kikukawa Y., Sasaki S
- Journal Title
  
  Chemical and Pharmaceutical Bulletin
  
  Volume: 67 Issue: 10 Pages: 1123-1130
- DOI
  10.1248/cpb.c19-00453
- NAID
  130007722037
- ISSN
  0009-2363, 1347-5223
- Year and Date
  2019-10-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19494
[Journal Article] Synthesis of the deuterated thymidine-d9 and deuterated oligonucleotides2019
- Author(s)
  Taniguchi Y., Cao X., Sasaki S.
- Journal Title
  
  Tetrahedron Letters
  
  Volume: 60 Issue: 38 Pages: 151037-151039
- DOI
  10.1016/j.tetlet.2019.151037
- Data Source
  KAKENHI-PROJECT-19H03351
[Journal Article] Stable and Selective Antiparallel Type Triplex DNA Formation by Targeting a GC Base Pair with the TFO Containing One N2-Phenyl-2′-deoxyguanosine2018
- Author(s)
 Yosuke Taniguchi, Mei Miyazaki, Nozomu Matsueda, Lei Wang, Hidenori Okamura, Shigeki Sasaki
- Journal Title
 
 Chemical and Pharmaceutical Bulletin
 
 Volume: 66 Issue: 6 Pages: 624-631
- DOI
 10.1248/cpb.c18-00043
- NAID
 130007382325
- ISSN
 0009-2363, 1347-5223
- Year and Date
 2018-06-01
- Language
 English
- Data Source
 KAKENHI-PROJECT-16H05100
[Journal Article] Modification of the aminopyridine unit of 2′-deoxyaminopyridinyl-pseudocytidine allowing triplex formation at CG interruptions in homopurine sequences2018
- Author(s)
  Lei Wang, Yosuke Taniguchi, Hidenori Okamura, Shigeki Sasaki
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 46 Issue: 17 Pages: 8678-8688
- DOI
  10.1093/nar/gky704
- Data Source
  KAKENHI-PROJECT-16H05100
[Journal Article] Development of Damaged Nucleoside Mimics for Inhibition of Their Repair Enzymes2017
- Author(s)
  Taniguchi Y
- Journal Title
  
  YAKUGAKU ZASSHI
  
  Volume: 137 Issue: 3 Pages: 293-300
- DOI
  10.1248/yakushi.16-00231-2
- NAID
  130005396861
- ISSN
  0031-6903, 1347-5231
- Year and Date
  2017-03-01
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K19494
[Journal Article] Effect of the 3-halosubstitution of the 2'-deoxy aminopyridinyl-pseudocytidine derivatives on the selectivity and stability ofantiparallel triplex DNA with a CG inversion site2017
- Author(s)
  Wang L., Taniguchi Y., Okamura H. and Sasaki S
- Journal Title
  
  Bioorg. Med.Chem.
  
  Volume: 23 Issue: 14 Pages: 1763-1769
- DOI
  10.1016/j.bmc.2017.05.035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05100
[Journal Article] Efficient Thymidine-Selective DNA Interstrand Photo-activated Crosslinking by the 6-Thioguanine Connected via an Ethylene-Linker to the 2′-Deoxyribose Unit2016
- Author(s)
 Nishioka Takamasa, Oshiro Ikuya, Onizuka Kazumitsu, Taniguchi Yosuke and Sasaki S
- Journal Title
 
 Chemical and Pharmaceutical Bulletin
 
 Volume: 64 Issue: 9 Pages: 1315-1320
- DOI
 10.1248/cpb.c16-00310
- NAID
 130005261564
- ISSN
 0009-2363, 1347-5223
- Language
 English
- Peer Reviewed / Acknowledgement Compliant
- Data Source
 KAKENHI-PROJECT-15H04633
[Journal Article] Aminopyridinyl-pseudodeoxycytidine derivatives selectively stabilize antiparalleltriplex DNA with multiple CG inversion sites2016
- Author(s)
  Okamura Hidenori, Taniguchi Yosuke, Sasaki Shigeki
- Journal Title
  
  Angew. Chem. Int. Ed.
  
  Volume: 128 Issue: 40 Pages: 12633-12637
- DOI
  10.1002/ange.201606136
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H04633, KAKENHI-PROJECT-26670056
[Journal Article] Recognition and detection of 8-oxo-rG in RNA using the DNA/OMeRNAchimera probes containing fluorescent adenosine-diazaphenoxazine analogue2016
- Author(s)
  Koga Yohie, Taniguchi Yosuke, Kikukawa Yoshiya, Sasaki Shigeki
- Journal Title
  
  Bioorg. Med. Chem.
  
  Volume: 24 Issue: 6 Pages: 1308-1313
- DOI
  10.1016/j.bmc.2016.02.001
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H04633
[Journal Article] Site-specific modification of the 6-amino group ofadenosine in RNA by an inter-strand functionality-transfer reaction using an S-functionalized-4-thiothymidine2015
- Author(s)
  Oshiro I. Jitsuzaki D. Onizuka K. Nishimoto A. Taniguchi Y. and Sasaki S
- Journal Title
  
  ChemBioChem,
  
  Volume: 16 Issue: 8 Pages: 1190-1198
- DOI
  10.1002/cbic.201500084
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H04633, KAKENHI-PROJECT-15J03430
[Journal Article] Discrimination Between 8-Oxo-2'-Deoxyguanosine and 2'-Deoxyguanosine in DNA by the Single Nucleotide Primer Extension Reaction with Adap Triphosphate2015
- Author(s)
  Taniguchi Y., Kikukawa Y and Sasaki S.
- Journal Title
  
  Angew. Chem. Int. Ed.
  
  Volume: 54 Pages: 5147-5151
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24689006
[Journal Article] Enhancement of TFO Triplex Formation by Conjugation with Pyrene via Click Chemistry2015
- Author(s)
 Taniguchi Y, Tomizaki A, Matsueda N, Okamura H, Sasaki S
- Journal Title
 
 Chemical and Pharmaceutical Bulletin
 
 Volume: 63 Issue: 11 Pages: 920-926
- DOI
 10.1248/cpb.c15-00570
- NAID
 130005105722
- ISSN
 0009-2363, 1347-5223
- Language
 English
- Peer Reviewed / Acknowledgement Compliant
- Data Source
 KAKENHI-PROJECT-26670056, KAKENHI-PROJECT-15H04633, KAKENHI-PROJECT-24689006
[Journal Article] Stabilization of the i-motif structure by the intra-strand cross-link formation.2015
- Author(s)
  K. Kikuta, H. Piao, J. Brazier, ,Y. Taniguchi, K.Onizuka, F. Nagatsugi, S. Sasaki
- Journal Title
  
  Bioorg. Med. Chem. Lett.
  
  Volume: 25 Issue: 16 Pages: 3307-3310
- DOI
  10.1016/j.bmcl.2015.05.064
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-15H05838, KAKENHI-PUBLICLY-26102710, KAKENHI-PROJECT-15H04633, KAKENHI-PROJECT-25288073
[Journal Article] An Isocytidine Derivative with a　2-Amino-6-methylpyridine Unit for Selective Recognition of the CG Interrupting Site in an Antiparallel Triplex DNA2014
- Author(s)
  Hidenori Okamura, Yosuke Taniguchi and Shigeki Sasaki
- Journal Title
  
  ChemBioChem
  
  Volume: 15 Issue: 16 Pages: 2374-2378
- DOI
  10.1002/cbic.201402328
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-13J04516, KAKENHI-PROJECT-24689006
[Journal Article] Remarkable acceleration of a DNA/RNA inter-strand functionality transfer reaction to modify a cytosine residue: the proximity effect via complexation with a metal cation2014
- Author(s)
  Jitsuzaki D., Onizuka K., Nishimoto A., Oshiro I., Taniguchi Y. and Sasaki S
- Journal Title
  
  Nucleic Acids Res
  
  Volume: 42 Issue: 13 Pages: 8808-8815
- DOI
  10.1093/nar/gku538
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24689006
[Journal Article] 2,6-Diaminopurine nucleoside derivative of 9-ethyloxy-2-oxo-1,3-diazaphenoxazine(2-amino-Adap) for recognition of 8-oxo-dG in DNA2014
- Author(s)
  Taniguchi Y., Fukabori K., Kikukawa Y., Koga Y and Sasaki S.
- Journal Title
  
  Bioorg. Med. Chem.
  
  Volume: 22(5) Issue: 5 Pages: 1634-1641
- DOI
  10.1016/j.bmc.2014.01.024
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229002, KAKENHI-PROJECT-24659047
[Journal Article] Synthesis of the Oligoribonucleotides Incorporating 8-Oxo-guanosine and Evaluation of their Base Pairing Properties2013
- Author(s)
  Koga Y., Taniguchi Y and Sasaki S.
- Journal Title
  
  Nucleosides, Nucleotides and Nucleic Acids
  
  Volume: 32(3) Issue: 3 Pages: 124-136
- DOI
  10.1080/15257770.2013.767461
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229002, KAKENHI-PROJECT-24659047
[Journal Article] N-(Guanidinoethyl)-2'-deoxy-5-methylisocytidine exhibits selective recognition of a CG interrupting site for the formation of anti-parallel triplexes2013
- Author(s)
  Hidenori Okamura, Yosuke Taniguchi and Shigeki Sasaki
- Journal Title
  
  Organic and Biomolecular Chemistry
  
  Volume: 11 Issue: 23 Pages: 3918-3924
- DOI
  10.1039/c3ob40472b
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13J04516, KAKENHI-PROJECT-21229002, KAKENHI-PROJECT-24689006
[Journal Article] Synthesis of 1'-phenyl-2-OMe ribose analogues connecting the thymine base at the 1' position through a flexible linker for the formation of a stable anti-parallele triplex DNA2013
- Author(s)
  Taniguchi Y., Okamura H., Fujino N., Sasaki S.
- Journal Title
  
  Tetrahedron
  
  Volume: 69(2) Issue: 2 Pages: 600-606
- DOI
  10.1016/j.tet.2012.11.016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229002, KAKENHI-PROJECT-24689006
[Journal Article] Synthesis of 8-oxoguanosine phosphoramidite and its incorporation into oligoribonucleotides2013
- Author(s)
  Taniguchi Y., Koga Y., Shigeki S.
- Journal Title
  
  Current Protocols in Nucleic Acid Chemistry
  
  Volume: UNIT4.58 Issue: 1
- DOI
  10.1002/0471142700.nc0458s56
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229002, KAKENHI-PROJECT-24659047
[Journal Article] An efficient antigene activity and antiproliferative effect by targeting the Bcl-2 or survivin gene with triplex forming oligonucleotides containing a W-shaped nucleoside analogue (WNA-βT)2012
- Author(s)
  Taniguchi, Y. and Sasaki, S.
- Journal Title
  
  Org. Biomol. Chem
  
  Volume: 10 Issue: 41 Pages: 8336-8341
- DOI
  10.1039/c2ob26431e
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229002, KAKENHI-PROJECT-24689006
[Journal Article] The Alkyl-Connected 2-Amino-6-Vinylprine (AVP) Crosslinking Agent for Improved Selectivity to the Cytosine Base in RNA2010
- Author(s)
  Yosuke Taniguchi
- Journal Title
  
  Bioorganic & Medicinal Chemistry (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790013
[Journal Article] Selective Fluorescence Quenching of the 8-OxoG-clamp by 8-Oxodeoxyguanosine in ODN, Bioorg2009
- Author(s)
  Nasr T., Li Z., Nakagawa O., Taniguchi Y., Ono S., Sasaki S.
- Journal Title
  
  Med. Chem. Lett. 19
  
  Pages: 727-730
- Data Source
  KAKENHI-PROJECT-17209001
[Journal Article] Recognition of the CG interrupting site by W-shaped nucleoside analogs (WNA) having the pyrozole ring in an anti-parallel triplex DNA2009
- Author(s)
  Yosuke Taniguchi
- Journal Title
  
  Bioorg Med.Chem 17
  
  Pages: 6803-6810
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790013
[Journal Article] Site-specific covalent modification of nucleic acids guided by functionality-transfer oligodeoxynucleotides2009
- Author(s)
  Onizuka K, Taniguchi Y., Sasaki S.
- Journal Title
  
  Bioconjugate Chem. 20
  
  Pages: 799-803
- Data Source
  KAKENHI-PROJECT-17209001
[Journal Article] Evaluation of the antisense effect of PEGylated oligodeoxynucleotides containing intelligent nucleoside analogues2009
- Author(s)
  Yosuke Taniguchi
- Journal Title
  
  Nucleic Acids Symp.Ser 53
  
  Pages: 167-168
- Data Source
  KAKENHI-PROJECT-20790013
[Journal Article] Recognition of the CG interrupting site by W-shaped nucleoside analogs (WNA) having the pyrozole ring in an anti-parallel triplex DNA2009
- Author(s)
  Yosuke Taniguchi, Yuko Uchida, Tomoko Takaki, Eriko Aoki, Shigeki Sasaki
- Journal Title
  
  Bioorg Med. Chem. 17
  
  Pages: 6803-6810
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790013
[Journal Article] Selective Fluorescence Quenching of the 8-OxoG-clamp by 8-Oxodeoxyguanosine in ODN2009
- Author(s)
  Nasr T, Li Z., Nakagawa O., Taniguchi Y., Ono S., Sasaki S.
- Journal Title
  
  Bioorg. Med. Chem. Lett. 19
  
  Pages: 727-730
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209001
[Journal Article] Synthesis of p-amino-WNA derivatives to enhance the stability o f the anti-parallel triplex2008
- Author(s)
  Yosuke Taniguchi, et.al.
- Journal Title
  
  Tetrahedron 64
  
  Pages: 7164-7170
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790013
[Journal Article] Synthesis of new nucleosides analogue connecting 2-amino-6-vinylpurine to the 2'-deoxyribose skeleton via the methylene linker.2008
- Author(s)
  Kurose Y., Taniguchi, Y., Nagatsugi R, Sasaki S.
- Journal Title
  
  Nucleic Acids Symp., Ser. 52
  
  Pages: 43-44
- Data Source
  KAKENHI-PROJECT-17209001
[Journal Article] Formation of a stable triplex incorporating a CG interrupting site by a new WNA derivative containing 3-aminopyrazole as a nucleobase.2008
- Author(s)
  Uchida Y., Taniguchi Y., Aoki E., Togo M., Sasaki S.
- Journal Title
  
  Nucleic Acids Symp. Ser. 52
  
  Pages: 137-138
- Data Source
  KAKENHI-PROJECT-17209001
[Journal Article] Formation of a stable triplex incorporating a CG interrupting site by a new WNA derivative containing 3-aminopyrazole as a nucleobase2008
- Author(s)
  Yuko Uchida, Yosuke Taniguchi, Eriko Aoki, Mieko Togo, Shigeki Sasaki
- Journal Title
  
  Nucleic Acids Symp. Ser. 52
  
  Pages: 137-138
- Data Source
  KAKENHI-PROJECT-20790013
[Journal Article] Site-specific modification by functionality-transfer oligonucleotide with the photo-inducible reactivity.2008
- Author(s)
  Onizuka K, Taniguchi Y., Nishioka X, Sasaki S.
- Journal Title
  
  Nucleic Acids Symp. Ser. 52
  
  Pages: 367-368
- Data Source
  KAKENHI-PROJECT-17209001
[Journal Article] Synthesis of p-amino-WNA derivatives to enhance the stability of the anti-parallel triplex2008
- Author(s)
  Taniguchi Y., Togo M., Aoki E., Uchida Y., Sasaki S.
- Journal Title
  
  Tetrahedron 64
  
  Pages: 7164-7170
- Data Source
  KAKENHI-PROJECT-17209001
[Journal Article] Synthesis of p-amino-WNA derivatives to enhance the stability of the anti-parallel triplex2008
- Author(s)
  Yosuke Taniguchi, Mieko Togo, Eriko Aoki, Yuko Uchida, Shigeki Sasaki
- Journal Title
  
  Tetrahedron 64
  
  Pages: 7164-7170
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790013
[Journal Article] Syntheses and properties of low-polarity shape mimics of 8-oxopurines2007
- Author(s)
  Yosuke Taniguchi, et. al.
- Journal Title
  
  Nucleic Acids Res.Symp.Ser 51
  
  Pages: 217-218
- Data Source
  KAKENHI-PROJECT-19890147
[Journal Article] Nonpolar Isosteres of Damaged DNA Bases:Effective Mimicry of Mutagenic Properties of 8-Oxopurines2007
- Author(s)
  Yosuke Taniguchi, et. al.
- Journal Title
  
  J.Am.Chem.Soc 129
  
  Pages: 8836-8844
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19890147
[Journal Article] Effects of the modified aromatic ring of WNA on stability of triplex DNA2006
- Author(s)
  Aoki E., Taniguchi Y., Togo M., Sasaki S.
- Journal Title
  
  Nucleic Acids Symp. Ser. 50
  
  Pages: 185-186
- Data Source
  KAKENHI-PROJECT-17209001
[Journal Article] Effects of Halogenated WNA Derivatives on Sequence Dependency for Expansion of Recognition Sequences in the Non-Natural Type Triplexes2006
- Author(s)
  Taniguchi Y., Nakamura A., Senko Y., Nagatsuki F., Sasaki S
- Journal Title
  
  J.Org.Chem (In press)
- Data Source
  KAKENHI-PROJECT-17209001
[Journal Article] Expansion of triplex recognition codes by the use of novel bicyclic nucleoside derivatives (WNA)2005
- Author(s)
  Taniguchi, T.; Nakamura, A.; Senko, Y.; Kodama, K.; Nagatsugi, F.; Sasaki, S.
- Journal Title
  
  Nucleosides Nucleotides Nucleic Acids 24
  
  Pages: 823-827
- Data Source
  KAKENHI-PROJECT-17209001
[Patent] Nucleoside analog derivative and utilization thereof2013
- Inventor(s)
  佐々木茂貴、谷口陽祐、深堀慶太郎
- Industrial Property Rights Holder
  九州大学
- Industrial Property Rights Type
  特許
- Filing Date
  2013-11-01
- Overseas
- Data Source
  KAKENHI-PROJECT-24659047
[Patent] Nucleoside analog derivative and utilization thereof2013
- Inventor(s)
  佐々木茂貴、谷口陽祐、深掘慶太郎
- Industrial Property Rights Holder
  佐々木茂貴、谷口陽祐、深掘慶太郎
- Industrial Property Rights Type
  特許
- Filing Date
  2013-11-01
- Overseas
- Data Source
  KAKENHI-PROJECT-24659047
[Presentation] Development an artificial nucleoside capable of recognizing 5mCG and CG base pairs and new application studies of triplex DNA2023
- Author(s)
  Ryotaro Notomi, Shigeki Sasaki, Yosuke Taniguchi
- Organizer
  ISNAC 2023 第50回国際核酸化学シンポジウム
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K27301
[Presentation] メチル化シトシンを含むDNAに対する3本鎖DNA形成核酸医薬の開発2023
- Author(s)
  納富亮大朗、佐々木茂貴、谷口陽祐
- Organizer
  日本核酸医薬学会　第８回年会
- Data Source
  KAKENHI-PROJECT-23K27301
[Presentation] 酸化損傷塩基を指標とした遺伝子診断に向けた人工核酸の開発2023
- Author(s)
  宮原涼, 谷口陽祐
- Organizer
  第39回メディシナルケミストリー
- Data Source
  KAKENHI-PROJECT-19H03351
[Presentation] Study on readthrough of premature termination codon by site-specific chemical modification2023
- Author(s)
  Jeongsu Lee, Hirotaka Murase, Norihiro Togo, Yosuke Taniguchi, Shigeki Sasaki
- Organizer
  ISNAC 2023 第50回国際核酸化学シンポジウム
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K27301
[Presentation] 酸化損傷塩基2-ヒドロキシアデニンを選択的に認識する人工核酸の開発2023
- Author(s)
  宮原涼、谷口陽祐
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-19H03351
[Presentation] DNA中の8-オキソグアノシン認識を目指した2’-デオキシシチジン誘導体の合成と機能評価2023
- Author(s)
  桜田喬登、近田佑太、宮原涼、谷口陽祐
- Organizer
  第60回化学関連支部合同九州大会
- Data Source
  KAKENHI-PROJECT-23K27301
[Presentation] mRNAの部位特異的分子修飾による未熟終止コドン（PTC）のリードスルー2023
- Author(s)
  村瀬裕貴、李政洙、谷口陽祐、佐々木茂貴
- Organizer
  日本核酸医薬学会　第８回年会
- Data Source
  KAKENHI-PROJECT-23K27301
[Presentation] RNA糖部2'-OHアセチル化のためのアミノピリジン結合プリン塩基の合成2023
- Author(s)
  李政洙、村瀬裕貴、古賀真優子、田崎史夏、大家千佳、高倉未遥、本郷克、谷口陽祐、佐々木茂貴
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-19H03351
[Presentation] Development of a new oligonucleotide agent for site-specific RNAs acetylation2023
- Author(s)
  Hirotaka Murase, Jeongsu Lee, Yosuke Taniguchi, Shuhei Imoto, Shigeki Sasaki
- Organizer
  ISNAC 2023 第50回国際核酸化学シンポジウム
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K27301
[Presentation] 遺伝子を制御するメチル化DNAに対して三本鎖DNAを形成可能にする人工核酸の開発とその応用研究2023
- Author(s)
  納富亮大朗、佐々木茂貴、谷口陽祐
- Organizer
  日本薬学会第143年会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03351
[Presentation] Selective Recognition of 2-Hydroxy-2’-Deoxyadenosine in DNA Using Pseudo-dC Derivatives2023
- Author(s)
  Ryo Miyahara, Yosuke Taniguchi
- Organizer
  ISNAC 2023 第50回国際核酸化学シンポジウム
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K27301
[Presentation] DNAメチル化領域に三本鎖DNAを形成可能にする人工核酸の開発2023
- Author(s)
  納富亮大朗, 佐々木茂貴, 谷口陽祐
- Organizer
  第39回メディシナルケミストリー
- Data Source
  KAKENHI-PROJECT-19H03351
[Presentation] 核酸だからできること2023
- Author(s)
  谷口陽祐
- Organizer
  第１０回バイオ関連シンポジウム若手フォーラム
- Invited
- Data Source
  KAKENHI-PROJECT-23K27301
[Presentation] 5mCG塩基対を含む三本鎖DNAを形成可能な人工核酸の開発と応用展開2023
- Author(s)
  納富亮大朗, 佐々木茂貴, 谷口陽祐
- Organizer
  第33回万有福岡シンポジウム
- Data Source
  KAKENHI-PROJECT-23K27301
[Presentation] 部位特異的化学修飾法を基盤としたRNAの分子修飾とラベル化2023
- Author(s)
  村瀬裕貴、都甲典弘、李政洙、谷口陽祐、佐々木茂貴
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-19H03351
[Presentation] 三本鎖DNA形成配列の拡張を可能とする合成を簡略化した新規人工核酸の開発2023
- Author(s)
  納富亮大朗、佐々木茂貴、谷口陽祐
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-19H03351
[Presentation] 人工核酸を用いた遺伝子標的核酸医薬の開発2023
- Author(s)
  谷口陽祐
- Organizer
  創薬・育薬特別講演会
- Invited
- Data Source
  KAKENHI-PROJECT-23K27301
[Presentation] Synthesis and Evaluation of 2’-Deoxycytidine Derivatives for the Recognition of 8-Oxo-2’-deoxyguanosine in DNA2023
- Author(s)
  Yuta Chikada, Takato Sakurada, Ryo Miyahara, Yosuke Taniguchi
- Organizer
  ISNAC 2023 第50回国際核酸化学シンポジウム
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K27301
[Presentation] 光クリック反応基を有する新規核酸ユニット分子の創製2023
- Author(s)
  米澤尚鴻、谷口陽祐
- Organizer
  第60回化学関連支部合同九州大会
- Data Source
  KAKENHI-PROJECT-23K27301
[Presentation] DNA配列中の8-oxo-dG認識選択性の向上を目指した新規人工核酸の開発2022
- Author(s)
  川添亮治、宮原涼、佐々木茂貴、谷口陽祐
- Organizer
  第59回化学関連支部合同九州大会
- Data Source
  KAKENHI-PROJECT-19H03351
[Presentation] 天然及び人工核酸の部位特異的化学修飾とその応用2022
- Author(s)
  村瀬裕貴、都甲典弘、李政洙、谷口陽祐、佐々木茂貴
- Organizer
  日本核酸医薬学会第7回年会
- Data Source
  KAKENHI-PROJECT-19H03351
[Presentation] 遺伝子発現制御に関与するメチル化シトシンを含む二本鎖DNAに対して三本鎖DNA形成を可能にする人工核酸の開発2022
- Author(s)
  納富亮大朗、王磊、佐々木茂貴、谷口陽祐
- Organizer
  日本ケミカルバイオロジー学会　第16回年会
- Data Source
  KAKENHI-PROJECT-19H03351
[Presentation] Simple and Efficient Method for Site-selective Internal Tritium Labeling of Chemically Modified Oligonucleotides2022
- Author(s)
  Hirotaka Murase, Jeongsu Lee, Yosuke Taniguchi andShigeki Sasaki
- Organizer
  ISNAC2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03351
[Presentation] Development of artificial nucleic acids that enable to form triplex DNA for DNA sequences containing 5mCG base pair2022
- Author(s)
  Ryotaro Notomi,Shigeki Sasaki and Yosuke Taniguchi
- Organizer
  ISNAC2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03351
[Presentation] 酸化損傷塩基2-オキソアデニンを特異的に認識しシーケンシングを目指した新規人工核酸の開発2022
- Author(s)
  宮原涼、谷口陽祐
- Organizer
  第16回バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PROJECT-19H03351
[Presentation] フォトクリック反応基を有する新規核酸ユニット分子の創製2022
- Author(s)
  米澤尚鴻、谷口陽祐
- Organizer
  第59回化学関連支部合同九州大会
- Data Source
  KAKENHI-PROJECT-19H03351
[Presentation] DNA中の酸化損傷塩基2-オキソアデニンを認識、検出する人工ヌクレオチドの開発2022
- Author(s)
  宮原涼、谷口陽祐
- Organizer
  日本ケミカルバイオロジー学会　第16回年会
- Data Source
  KAKENHI-PROJECT-19H03351
[Presentation] TA塩基対を含む2本鎖DNAに対し3本鎖DNAを形成可能なプリンヌクレオシド誘導体の開発2022
- Author(s)
  伊藤聖紘、納富亮大朗、王磊、佐々木茂貴、谷口陽祐
- Organizer
  第59回化学関連支部合同九州大会
- Data Source
  KAKENHI-PROJECT-19H03351
[Presentation] 遺伝子発現を調節するメチル化DNA配列に対して三本鎖DNAを形成可能にする人工核酸の開発2022
- Author(s)
  納富亮大朗、王磊、佐々木茂貴、谷口陽祐
- Organizer
  日本核酸医薬学会第7回年会
- Data Source
  KAKENHI-PROJECT-19H03351
[Presentation] DNA配列中の8-oxo-dG認識特異性の向上を目指した7-deaza-Adapのトリリン酸体の開発2021
- Author(s)
  川添亮治、長田悠佑、桜田喬登、宮原涼、佐々木茂貴、谷口陽祐
- Organizer
  第38回日本薬学会九州山口支部大会
- Data Source
  KAKENHI-PROJECT-19H03351
[Presentation] Development of 7-deaza-purine-1,3-diazaphenoxazine nucleotide derivative for the selective recognition of 8-oxo-2'-deoxyguanosine in DNA2021
- Author(s)
  Ryoji Kawazoe, Yusuke Nagata, Ryo Miyahara, Takato Sakurada, Shigeki Sasaki, Yosuke Taniguchi
- Organizer
  2021 CSPS/PSJ/CC-CRS Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03351
[Presentation] 2本鎖DNAを標的としたアンチジーン核酸医薬2021
- Author(s)
  谷口陽祐
- Organizer
  日本薬学会第１４２年会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03351
[Presentation] TA塩基対を認識し安定な3本鎖DNA形成を目指したプリン骨格を有する新規核酸類似体の「合成と機能評価2021
- Author(s)
  伊藤聖紘、納富亮太朗、王磊、佐々木茂貴、谷口陽祐
- Organizer
  日本薬学会第１４２年会
- Data Source
  KAKENHI-PROJECT-19H03351
[Presentation] 5mCG塩基対を含む二本鎖DNAに対し三本鎖DNAを形成可能な人工核酸の開発2021
- Author(s)
  納富亮太朗、王磊、佐々木茂貴、谷口陽祐
- Organizer
  日本薬学会第１４２年会
- Data Source
  KAKENHI-PROJECT-19H03351
[Presentation] 官能基転移人工核酸によるmRNA部位特異的修飾と翻訳への効果の検討2021
- Author(s)
  都甲典宏、菊田健司、村瀬裕貴、谷口陽祐、佐々木茂貴
- Organizer
  日本薬学会　第１４１年会
- Data Source
  KAKENHI-PROJECT-19H03351
[Presentation] Synthesis and evaluation of C-nucleotide derivatives2021
- Author(s)
  Ryotaro Notomi, Lei Wang, Shigeki Sasaki, Yosuke Taniguchi
- Organizer
  ISNAC2021（日本核酸化学会第5回年会）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03351
[Presentation] Development of aniline modified aminonebularine derivatives for the formation of anti-parallel type of triplex DNA2021
- Author(s)
  Ryotaro Notomi, Lei Wang, Shigeki Sasaki, Yosuke Taniguchi
- Organizer
  2021 CSPS/PSJ/CC-CRS Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03351
[Presentation] Development of aminopurine derivative for recognition 5-methyl CG base pair in anti-parallel triplex DNA2021
- Author(s)
  Ryotaro Notomi, Lei Wang, Shigeki Sasaki, Yosuke Taniguchi
- Organizer
  FIBER日本核酸化学会若手フォーラ
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03351
[Presentation] 核酸修復酵素活性阻害能を有する損傷核酸ヌクレオチド誘導体の開発2021
- Author(s)
  石川廉、石卉、Heh Choon Han、佐々木茂貴、谷口陽祐
- Organizer
  日本ケミカルバイオロジー学会　第15回年会
- Data Source
  KAKENHI-PROJECT-19H03351
[Presentation] Development of aminonebularine derivatives for the recognition og duplex DNA including a 5-methyl CG base pair in an antiparallel triplex DNA2021
- Author(s)
  Ryo Miyahara, Yosuke Taniguchi
- Organizer
  ISNAC2021（日本核酸化学会第5回年会）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03351
[Presentation] 3本鎖DNA中のTA塩基対認識を目指したプリン骨格を有する核酸誘導体の合成と評価2021
- Author(s)
  伊藤聖紘、納富亮太朗、王磊、佐々木茂貴、谷口陽祐
- Organizer
  第38回日本薬学会九州山口支部大会
- Data Source
  KAKENHI-PROJECT-19H03351
[Presentation] 8-オキソグアノシンの選択的認識を目指したピリミジン骨格を有する人工ヌクレオチドの開発2021
- Author(s)
  桜田喬登、長田悠佑、佐々木茂貴、谷口陽祐
- Organizer
  第５８回化学関連支部合同九州大会
- Data Source
  KAKENHI-PROJECT-19H03351
[Presentation] 酸化損傷塩基2-オキソアデニンを選択的に認識する人工ヌクレオチドの開発2021
- Author(s)
  宮原涼、谷口陽祐
- Organizer
  日本薬学会第１４２年会
- Data Source
  KAKENHI-PROJECT-19H03351
[Presentation] 三本鎖DNA形成領域拡張のための5mCG塩基対認識人工核酸の開発2021
- Author(s)
  納富亮大朗、王磊、佐々木茂貴、谷口陽祐
- Organizer
  日本薬学会　第１４１年会
- Data Source
  KAKENHI-PROJECT-19H03351
[Presentation] 官能基転移人工核酸によるmRNA部位特異的なラベル化法の確立と翻訳制御法への展開2021
- Author(s)
  都甲典宏、村瀬裕貴、イジョンス、菊田健司、谷口陽祐、佐々木茂貴
- Organizer
  第５８回化学関連支部合同九州大会
- Data Source
  KAKENHI-PROJECT-19H03351
[Presentation] エピジェネティック制御に関与する5-メチルCG塩基対に対し三本鎖DNAを形成可能にする人工核酸の開発2021
- Author(s)
  納富亮大朗、王磊、佐々木茂貴、谷口陽祐
- Organizer
  日本核酸医薬学会第6回年会
- Data Source
  KAKENHI-PROJECT-19H03351
[Presentation] ８－オキソグアノシンのDNA配列中位置検出を目指したデアザプリン人工ヌクレオチドの開発と評価2021
- Author(s)
  長田悠佑、相良委公子、佐々木茂貴、谷口陽祐
- Organizer
  日本薬学会　第１４１年会
- Data Source
  KAKENHI-PROJECT-19H03351
[Presentation] 酸化損傷塩基の認識向上を目指したピリジン骨格を有する人工ヌクレオチドの開発2021
- Author(s)
  桜田喬登、長田悠佑、佐々木茂貴、谷口陽祐
- Organizer
  日本薬学会　第１４１年会
- Data Source
  KAKENHI-PROJECT-19H03351
[Presentation] The synthesis of oligonucleotide incorporating 2-methoxycarbonyl-6-aminopurine for post-synthetic modifications2021
- Author(s)
  Jeongsu Lee, Hirotaka Murase, Hayate Takasaki, Yosuke Taniguchi, Shigeki Sasaki
- Organizer
  2021 CSPS/PSJ/CC-CRS Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03351
[Presentation] 二本鎖DNA中の5メチルCG塩基対を認識し三本鎖DNA形成を可能とする人工核酸の合成と機能評価2021
- Author(s)
  納富亮大朗、王磊、佐々木茂貴、谷口陽祐
- Organizer
  第45回反応と合成の進歩シンポジウ
- Data Source
  KAKENHI-PROJECT-19H03351
[Presentation] リボース２’OH選択的アセチル化のための触媒基導入ヌクレオシドの開発2021
- Author(s)
  李政洙、村瀬裕貴、古賀真優子、田崎史夏、谷口陽祐、佐々木茂貴
- Organizer
  日本薬学会第１４２年会
- Data Source
  KAKENHI-PROJECT-19H03351
[Presentation] DNA配列中の8-oxo-dG特異的認識を目指した7-deaza-Adapの合成と機能評価2021
- Author(s)
  川添亮治、長田悠佑、桜田喬登、宮原涼、佐々木茂貴、谷口陽祐
- Organizer
  日本薬学会第１４２年会
- Data Source
  KAKENHI-PROJECT-19H03351
[Presentation] γ位修飾８-oxo-dGTPによる酸化損傷修復酵素活性検出法の開発2021
- Author(s)
  丸山健登、石川廉、石卉、佐々木茂貴、谷口陽祐
- Organizer
  日本薬学会　第１４１年会
- Data Source
  KAKENHI-PROJECT-19H03351
[Presentation] 反応性核酸を用いた環境応答型solvatochromic蛍光分子の蛋白質への導入と修飾蛋白質の評価2020
- Author(s)
  麻生真理子、金城綾香、田畑香織、阿部由紀子、谷口陽祐、佐々木茂貴
- Organizer
  第14回バイオ関連化学シンポジウム2020
- Data Source
  KAKENHI-PROJECT-19H03351
[Presentation] ３本鎖DNA形成領域の拡張を目指した５-メチルCG塩基対を認識可能な人工核酸の開発2020
- Author(s)
  納富亮大朗、谷口陽祐、小薄孝行、佐々木茂貴
- Organizer
  日本薬学会第140回年会
- Data Source
  KAKENHI-PROJECT-19H03351
[Presentation] 遺伝子を標的とした人工核酸搭載核酸医薬の新展開2020
- Author(s)
  谷口陽祐、佐々木茂貴
- Organizer
  第69回高分子討論会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03351
[Presentation] アンチジーン核酸の開発を指向した人工核酸の合成と核移行核酸の創成2020
- Author(s)
  谷口陽祐
- Organizer
  核酸医薬シンポジウム２０２０
- Invited
- Data Source
  KAKENHI-PROJECT-19H03351
[Presentation] CG塩基対とアンチパラレル型三本鎖DNAを形成するC-ヌクレオシドアナログの開発2020
- Author(s)
  納富亮大朗、王磊、佐々木茂貴、谷口陽祐
- Organizer
  2020年日本化学会九州支部秋期研究発表会
- Data Source
  KAKENHI-PROJECT-19H03351
[Presentation] DNA配列中での８-オキソグアノシン発生位置検出を目指したデアザプリン人工ヌクレオチデオチドの開発と評価2020
- Author(s)
  長田悠佑、谷口陽祐、相良委公子、菊川誉也、佐々木茂貴
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-17K19494
[Presentation] Development of 7,8-disubstituted 7-deazadG nucleotide derivatives as 8-oxo-dG triphosphatase inhibitors2019
- Author(s)
  Hui Shi, Yizhen Yin, Shigeki Sasaki, Yosuke Taniguchi
- Organizer
  第46回国際核酸化学シンポジウム（ISNAC2019）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19494
[Presentation] ５－メチルCG塩基対を認識し３本鎖DNA形成を可能にする人工核酸の開発2019
- Author(s)
  納富亮大朗、谷口陽祐、小薄孝行、佐々木茂貴
- Organizer
  第１３回バイオ関連化学シンポジウム２０１９
- Data Source
  KAKENHI-PROJECT-19H03351
[Presentation] ８－オキソグアノシンを選択的に認識するデアザプリン人工ヌクレオチドの開発2019
- Author(s)
  長田悠佑、谷口陽祐、相良委公子、菊川誉也、佐々木茂貴
- Organizer
  第５６回化学関連支部合同九州大会
- Data Source
  KAKENHI-PROJECT-17K19494
[Presentation] 酸化損傷塩基を認識可能なフェノキサジン環を有する人工ヌクレオチドの合成と機能評価2019
- Author(s)
  谷口陽祐、菊川誉也、相良委公子、長田悠佑、佐々木茂貴
- Organizer
  第45回反応と合成の進歩シンポジウム
- Data Source
  KAKENHI-PROJECT-17K19494
[Presentation] ５－メチルCG塩基対の認識を目指した３本鎖DNA形成人工核酸の開発2019
- Author(s)
  納富亮大朗、谷口陽祐、小薄孝行、佐々木茂貴
- Organizer
  第５６回化学関連支部合同九州大会
- Data Source
  KAKENHI-PROJECT-19H03351
[Presentation] 三本鎖DNA中で5-メチルCG塩基対を認識可能な人工核酸の合成と評価2019
- Author(s)
  納富亮大朗、谷口陽祐、小薄孝行、佐々木茂貴
- Organizer
  第36回日本薬学会九州支部大会
- Data Source
  KAKENHI-PROJECT-19H03351
[Presentation] ８－オキソグアノシンを選択的に認識するデアザプリン人工ヌクレオチドの開発2019
- Author(s)
  長田悠佑、谷口陽祐、相良委公子、菊川誉也、佐々木茂貴
- Organizer
  第３１回若手研究者のためのセミナー
- Data Source
  KAKENHI-PROJECT-17K19494
[Presentation] Development of artificial nucleoside for 5-methyl CG base pair recognition in antiparallel triplex DNA2019
- Author(s)
  Ryotaro Notomi, Yosuke Taniguchi, Takayuki Osuki, Shigeki Sasaki
- Organizer
  第46回国際核酸化学シンポジウム（ISNAC2019）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03351
[Presentation] Design and synthesis of the pseudo-dC derivatives for the formation of an antiparallel type of triplex DNA2019
- Author(s)
  Yosuke Taniguchi, Lei Wang, Hidenori Okamura and Shigeki Sasaki
- Organizer
  CISNAC2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03351
[Presentation] γ-アミドトリリン酸の簡易的な合成法の確立と酵素伸長反応への利用2019
- Author(s)
  桜田喬登、谷口陽祐、長田悠佑、佐々木茂貴
- Organizer
  第36回日本薬学会九州支部大会
- Data Source
  KAKENHI-PROJECT-17K19494
[Presentation] Synthesis and evaluation of deazapurine nucleotide analogue selectivity recognizing 8-oxo-2'-deoxyguanosine in DNA2019
- Author(s)
  Yusuke Nagata, Yosuke Taniguchi, Ikuko Sagara, Yoshiya KIkukawa, Shigeki Sasaki
- Organizer
  第46回国際核酸化学シンポジウム（ISNAC2019）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19494
[Presentation] ８－オキソグアノシン選択的認識を目指したデアザプリン人工ヌクレオチドの開発と評価2019
- Author(s)
  長田悠佑、谷口陽祐、相良委公子、菊川誉也、佐々木茂貴
- Organizer
  第36回日本薬学会九州支部大会
- Data Source
  KAKENHI-PROJECT-17K19494
[Presentation] 三本鎖形成配列の拡張を目的としたC-ヌクレオシド誘導体の合成と評価2019
- Author(s)
  小薄孝行、谷口陽祐、真方　裕哉、佐々木　茂貴
- Organizer
  日本ケミカルバイオロジー学会第１４回年会
- Data Source
  KAKENHI-PROJECT-19H03351
[Presentation] 損傷DNAを配列特異的に増やす、探る人工核酸2019
- Author(s)
  谷口陽祐
- Organizer
  第９２回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-17K19494
[Presentation] Development of non-natural type anti-parallel triplex DNA formation using TFOs containing artificial nucleoside analogues2019
- Author(s)
  Yosuke Taniguchi, Hidenori Okamura, Lei Wang and Shigeki Sasaki
- Organizer
  The 27th French-Japanese Symposium on Medicinal and Fine CHemistry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03351
[Presentation] 酸化損傷核酸のγ位修飾体による修復酵素への結合と活性阻害評価2018
- Author(s)
  丸山健登、Ninticha THAVONCHAROENSUB、重松慶治、佐々木茂貴、谷口陽祐
- Organizer
  日本薬学会第139回年会
- Data Source
  KAKENHI-PROJECT-17K19494
[Presentation] Developmentof C-nucleoside analogues for a TA base pair recognition in antiparallel triplex DNA2018
- Author(s)
  Takayuki Osuki, Yosuke Taniguchi, Yuya Magata, Shigeki Sasaki
- Organizer
  第45回国際核酸化学シンポジウム
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05100
[Presentation] 光誘起能をもつRNAアシル化反応の検討2018
- Author(s)
  菊田健司　Jan BARTA　谷口陽祐　佐々木茂貴
- Organizer
  日本薬学会大１３８年会
- Data Source
  KAKENHI-PROJECT-15H04633
[Presentation] Triplex DNA as an antigene methid: Design, synthesis and evaluation of articicial nucleic acid2018
- Author(s)
  Yosuke Taniguchi
- Organizer
  Kyushu University-University Malaya Pharmacy Symposium 2018
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05100
[Presentation] 3本鎖DNA中のTA塩基対の認識を目指したC-ヌクレオシドの合成と3本鎖形成能評価2018
- Author(s)
  真方祐哉、谷口陽祐、岡村秀紀、佐々木茂貴
- Organizer
  日本薬学会第138回年会
- Data Source
  KAKENHI-PROJECT-16H05100
[Presentation] Synthesis and evaluation of modified 7-deaza-dG triphosphate derivatives for 8-oxo-dGTP mimicry2018
- Author(s)
  Yosuke Taniguchi, Hui Shi, Yoshiharo Shigematsu, Shigeki Sasaki
- Organizer
  XXIII International Roundtable on Nucleosides, Nucleotides and Nucleic Acids
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19494
[Presentation] CpGアイランドを認識する人工ペプチド核酸の設計と合成2018
- Author(s)
  楊昊、谷口陽祐、岡村秀紀、Lei WANG、佐々木茂貴
- Organizer
  日本薬学会第138回年会
- Data Source
  KAKENHI-PROJECT-16H05100
[Presentation] Substitution effet on aminopyridinyl-pseudodeoxycytidine derivatives on the selectivity and stability of antiparallel triplex DNA with CG inversion site2018
- Author(s)
  王磊、谷口陽祐、岡村秀紀、佐々木茂貴
- Organizer
  第4回日本核酸医薬学会
- Data Source
  KAKENHI-PROJECT-16H05100
[Presentation] Development of the pseudo-dC derivatives for thre recognition of CG inversion sites by an antiparallel triplex DNA for the antigenestrategy2018
- Author(s)
  Yosuke Taniguchi, Lei Wang, Hidenori Okamura, Shigeki Sasaki
- Organizer
  Functional Nucleic Acids (FNA) PERTH 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05100
[Presentation] RNA糖部2'位OH基を配列特異的に修飾する人工核酸の開発2018
- Author(s)
  北﨑健太郎　高崎隼颯　谷口陽祐　佐々木茂貴
- Organizer
  日本薬学会大１３８年会
- Data Source
  KAKENHI-PROJECT-15H04633
[Presentation] Chemicalmodifications of aminopyridine unit of 2'-deoxyaminopyridinyl-pseudocytidine totune the recognition ability for the formation of the triplex DNA with CGinversion sites2018
- Author(s)
  Lei Wang, Yosuke Taniguchi, Hidenori Okamura, Shigeki Sasaki
- Organizer
  第45回国際核酸化学シンポジウム
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05100
[Presentation] Synthesisand evaluation of 7,8-disubstituted 7-deazad-dGTP derivatives as hMTH1 Inhibitors2018
- Author(s)
  Hui Shi, Zhen Yi Yin, Shigeki Sasaki, Yosuke Taniguchi
- Organizer
  第45回国際核酸化学シンポジウム
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19494
[Presentation] Design and Synthesis of Artificial nucleoside Analogue for the Expansion of the Triplax DNA Frorming Code with High Stability andSelectivity2018
- Author(s)
  Yosuke Taniguchi
- Organizer
  Asian 3 Roundtable on Nucleic Acids A3RONA 2018
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05100
[Presentation] Synthesis and evaluation of substituted 7-deazadGtriphosphate derivatives as hMTH1 inhibitors2018
- Author(s)
  Yosuke Taniguchi
- Organizer
  KU-NTU Joint International Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19494
[Presentation] 三本鎖形成配列の拡張を目的としたTA塩基対認識可能なC-ヌクレオシド誘導体の合成と評価2018
- Author(s)
  小薄孝行、谷口陽祐、真方　裕哉、佐々木　茂貴
- Organizer
  日本薬学会第139回年会
- Data Source
  KAKENHI-PROJECT-16H05100
[Presentation] トリリン酸γ位修飾体による酸化損傷修復酵素への結合と活性阻害評価2018
- Author(s)
  丸山健登、重松慶治、石卉、佐々木茂貴、谷口陽祐
- Organizer
  第55回化学関連支部合同九州大会
- Data Source
  KAKENHI-PROJECT-17K19494
[Presentation] γ位修飾トリリン酸によるhMTH1への結合と活性阻害評価2018
- Author(s)
  丸山健登、重松慶治、石卉、佐々木茂貴、谷口陽祐
- Organizer
  第30回若手研究者のためのセミナー
- Data Source
  KAKENHI-PROJECT-17K19494
[Presentation] TA塩基対認識能の向上を目指したC-ヌクレオシド誘導体の合成と3本鎖形成能の評価2018
- Author(s)
  小簿孝行、谷口陽祐、真方祐哉、佐々木茂貴
- Organizer
  第55回化学関連支部合同九州大会
- Data Source
  KAKENHI-PROJECT-16H05100
[Presentation] 7,８修飾7-デアザグアノシントリリン酸誘導体によるhMTH1阻害剤の開発2018
- Author(s)
  石卉、尹貽貞、佐々木茂貴、谷口陽祐
- Organizer
  日本薬学会第139回年会
- Data Source
  KAKENHI-PROJECT-17K19494
[Presentation] 非ワトソンクリック型水素結合可能な人工核酸による非天然型3本鎖DNA形成とその核酸医薬への展開2018
- Author(s)
  谷口陽祐
- Organizer
  非ワトソン・クリック型核酸に関する九州地区セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-16H05100
[Presentation] An Attempt to Photo-induced RNA Acetylation by Oligonucleotides Containing 1-Acetyl-7-nitroindolines2017
- Author(s)
  Kenji Kikuta　 Jan Barta　 Yosuke Taniguchi　 Shigeki Sasaki
- Organizer
  The 1st Annual Meeting of Japan Society of Nucleic Acids Chemistry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04633
[Presentation] DNA中のTA塩基対の認識を目指した C-ヌクレオシドの合成と機能評価2017
- Author(s)
  真方祐哉、谷口陽祐、岡村秀紀、佐々木茂貴
- Organizer
  第34回日本薬学会九州支部大会
- Data Source
  KAKENHI-PROJECT-16H05100
[Presentation] 長鎖 mRNA に対する部位特異的化学修飾を利用した翻訳制御の評価2017
- Author(s)
  松本卓也, 大城郁也, 實崎大地, 谷口陽祐, 佐々木茂貴
- Organizer
  日本薬学会第137回年会
- Place of Presentation
  仙台市
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-15H04633
[Presentation] Effect of the 3-position modifications of the 2?-deoxyaminopyridinyl-pseudocytidine derivatives on the selectivity and stability of　antiparallel triplex DNA with a CG inversion site2017
- Author(s)
  Lei Wang, Yosuke Taniguchi, Hidenori Okamura,Shigeki Sasaki
- Organizer
  The 1st Annual Meeting of Japan Society of Nucleic Acids Chemistry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05100
[Presentation] ８位修飾７デアザグアノシン誘導体による核酸修復酵素阻害剤の創製2017
- Author(s)
  谷口陽祐、尹貽貞、石卉、重松慶治、佐々木茂貴
- Organizer
  第３５回メディシナルケミストリーシンポジウム、
- Data Source
  KAKENHI-PROJECT-16H05100
[Presentation] Design and synthesis of peptide nucleic acids (PNA)for binding to CpG island2017
- Author(s)
  Hao Yang, Yosuke Taniguchi, Hidenori Okamura, LeiWang, Shigeki Sasaki
- Organizer
  The 1st Annual Meeting of Japan Society of Nucleic Acids Chemistry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05100
[Presentation] 8-Oxo-dG認識の向上を目指した2-Chloro-Adapの合成と評価2017
- Author(s)
  相良委公子、谷口陽祐、菊川誉也、佐々木茂貴
- Organizer
  第54回化学関連支部合同九州大会
- Data Source
  KAKENHI-PROJECT-17K19494
[Presentation] 誘起反応性アルキル架橋剤を用いたmRNAのアンチセンス阻害と i-motifの安定化2017
- Author(s)
  菊田健司　朴海順　John Brazier　鬼塚和光　永次史　谷口陽祐　佐々木茂貴
- Organizer
  日本核酸医薬学会第3回年会
- Data Source
  KAKENHI-PROJECT-15H04633
[Presentation] ８位修飾７デアザグアノシン誘導体による核酸修復酵素阻害剤の創製2017
- Author(s)
  谷口陽祐、尹貽貞、石卉、重松慶治、佐々木茂貴
- Organizer
  第３５回メディシナルケミストリーシンポジウム
- Data Source
  KAKENHI-PROJECT-17K19494
[Presentation] 3本鎖DNA中のTA塩基対の認識を目指した人工核酸の合成と3本鎖形成能評価2017
- Author(s)
  真方祐哉、谷口陽祐、岡村秀紀、佐々木茂貴
- Organizer
  第54回化学関連支部合同九州大会
- Data Source
  KAKENHI-PROJECT-16H05100
[Presentation] アンチジーン核酸創薬を志向した非天然型3本鎖DNA形成可能な核酸誘導体の開発2017
- Author(s)
  谷口陽祐
- Organizer
  日本核酸医薬学会第3回年会
- Invited
- Data Source
  KAKENHI-PROJECT-16H05100
[Presentation] 3 本鎖 DNA 中の TA 塩基対を選択的に認識可能な人工核酸の合成2017
- Author(s)
  真方祐哉、谷口陽祐、岡村秀紀、佐々木茂貴
- Organizer
  日本薬学会第137回年会
- Place of Presentation
  仙台
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-16H05100
[Presentation] クロスリンクを RNA 部位特異的に形成する人工核酸の開発と翻訳制御の検討2017
- Author(s)
  菊田健司, 谷口陽祐, 佐々木茂貴
- Organizer
  日本薬学会第137回年会
- Place of Presentation
  仙台市
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-15H04633
[Presentation] RNA糖部2'位のOH基を位置特異的に修飾する人工核酸の開発2017
- Author(s)
  北﨑健太郎　高崎隼颯　谷口陽祐　佐々木茂貴
- Organizer
  第54回化学関連支部合同九州大会
- Data Source
  KAKENHI-PROJECT-15H04633
[Presentation] RNA 部位特異的化学修飾能を持つ官能基転移核酸の開発と遺伝情報制御法への応用2017
- Author(s)
  大城郁也, 松本卓也, 實崎大地, 谷口陽祐, 佐々木茂貴
- Organizer
  日本薬学会第137回年会
- Place of Presentation
  仙台市
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-15H04633
[Presentation] CG塩基対を選択的に認識する擬シチジン誘導体の合成と3本鎖DNA形成能の機能評価2017
- Author(s)
  谷口陽祐、岡村秀紀、王磊、佐々木茂貴
- Organizer
  第43回反応と合成の進歩シンポジウム
- Data Source
  KAKENHI-PROJECT-16H05100
[Presentation] 核酸修復酵素阻害剤を目指した損傷類似人工核酸の開発2017
- Author(s)
  谷口陽祐、尹貽貞、石卉、重松慶治、佐々木茂貴
- Organizer
  日本ケミカルバイオロジー学会第12回年会、
- Data Source
  KAKENHI-PROJECT-16H05100
[Presentation] Synthesis and evaluation of nucleoside analoguesfor the recognition of a TA base pair within the triplex DNA2017
- Author(s)
  Hui Shi, Shigeki Sasaki, Yosuke Taniguchi
- Organizer
  The 1st Annual Meeting of Japan Society of Nucleic Acids Chemistry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19494
[Presentation] 糖部 2' 位 OH 基を配列特異的に修飾する人工核酸の開発2017
- Author(s)
  北﨑健太郎　高崎隼颯　谷口陽祐　佐々木茂貴
- Organizer
  第34回日本薬学会九州支部大会
- Data Source
  KAKENHI-PROJECT-15H04633
[Presentation] Development of pyrimidine nucleoside analogs as inducible cross-linking agents for nucleic acids2016
- Author(s)
  Kenji Kikuta, Yosuke Taniguchi and Shigeki Sasaki
- Organizer
  The 25th French-Japanese Symposium on Medicinal and Fine Chemistry
- Place of Presentation
  東京都多摩市
- Year and Date
  2016-05-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04633
[Presentation] Oligonucleotides incorporating the 4-vinylpyrimidine derivatives to investigate the cross-link formation with mRNA2016
- Author(s)
  Kenji Kikuta, Yosuke Taniguchi and Shigeki Sasaki
- Organizer
  第43回国際核酸化学シンポジウム
- Place of Presentation
  熊本
- Year and Date
  2016-09-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04633
[Presentation] Non-natural nucleoside derivatives for selective stabilization of the antiparallel triplex DNA with multiple inversion sites2016
- Author(s)
  Hidenori Okamura, Yosuke Taniguchi andShigeki Sasaki
- Organizer
  The First A3 Roundtable Meeting on Chemical Probe Research Hub
- Place of Presentation
  Fukuoka
- Year and Date
  2016-09-22
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670056
[Presentation] RNA部位特異的化学修飾能を持つ官能基転移核酸の開発と遺伝情報制御法への展開2016
- Author(s)
  大城郁也，實崎大地，松本卓也，谷口陽祐，佐々木茂貴
- Organizer
  第14回次世代を担う有機化学シンポジウム
- Place of Presentation
  東京都渋谷区
- Year and Date
  2016-05-27
- Data Source
  KAKENHI-PROJECT-15H04633
[Presentation] 自己活性化能をもつピリミジン型クロスリンク核酸の開発2016
- Author(s)
  菊田健司、谷口陽祐、佐々木茂貴
- Organizer
  日本薬学会第１３６回年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-26
- Data Source
  KAKENHI-PROJECT-15H04633
[Presentation] Synthesis of the N2-substituted 2'-deoxyguanosine derivatives and the binding evaluation for the triplex DNA formation2016
- Author(s)
  Mei Miyazaki, Yosuke Taniguchi, Nozomu Matsueda and Shigeki Sasaki
- Organizer
  第43回国際核酸化学シンポジウム
- Place of Presentation
  Kumamoto
- Year and Date
  2016-09-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670056
[Presentation] Synthesis of the N2-substituted 2'-deoxyguanosine derivatives and the binding evaluation for the triplex DNA formation2016
- Author(s)
  Mei Miyazaki, Yosuke Taniguchi, Nozomu Matsueda and Shigeki Sasaki
- Organizer
  第43回国際核酸化学シンポジウム
- Place of Presentation
  熊本
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05100
[Presentation] N2-フェニル置換グアノシン誘導体によるPhdG/GC3重鎖塩基対特異性の向上2016
- Author(s)
  宮﨑芽依、谷口陽祐、佐々木茂貴
- Organizer
  第３３回日本薬学会九州支部大会
- Place of Presentation
  鹿児島
- Year and Date
  2016-12-03
- Data Source
  KAKENHI-PROJECT-16H05100
[Presentation] Design of the reactive nucleoside analogs and its incorporation into the oligonucleotised for the site-selective chemicalmodification of the 2'-hydroxyl group of RNA2016
- Author(s)
  Hayate Takasaki,Yurie Hadano, Yosuke Taniguchi and Shigeki Sasaki
- Organizer
  第43回国際核酸化学シンポジウム
- Place of Presentation
  熊本
- Year and Date
  2016-09-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04633
[Presentation] ＧＣ塩基対に対する親和性の向上を目指したN-2置換グアノシン誘導体の開発2016
- Author(s)
  宮﨑芽依、谷口陽祐、松枝望、佐々木茂貴
- Organizer
  第５３回化学関連支部合同九州大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-26670056
[Presentation] The Functionality Transfer Oligonucleotides for Site-Selective Modification of Cytidine or Adenine2016
- Author(s)
  Shigeki Sasaki, Daichi Jitsuzaki, Ikuya Oshiro, Kazumitsu Onizuka, Atsushi Nishimoto, Yosuke Taniguchi
- Organizer
  XXIIInternational Roundtable on Nucleosides Nucleotides and Nucleic Acids
- Place of Presentation
  Paris
- Year and Date
  2016-07-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04633
[Presentation] Non-natural nucleoside derivatives for selective stabilization of the antiparallel triplex DNA with multiple inversion sites2016
- Author(s)
  Hidenori Okamura, Yosuke Taniguchi andShigeki Sasaki
- Organizer
  The First A3 Roundtable Meeting on Chemical Probe Research Hub
- Place of Presentation
  福岡市
- Year and Date
  2016-09-22
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04633
[Presentation] 損傷類似人工核酸による核酸修復酵素阻害剤の開発2016
- Author(s)
  谷口陽祐
- Organizer
  日本薬学会第１３６回年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-26
- Invited
- Data Source
  KAKENHI-PROJECT-24689006
[Presentation] RNAの2’位水酸基を配列特異的に修飾する人工核酸の開発2016
- Author(s)
  高崎隼颯, 羽田野友里恵, 谷口陽祐, 佐々木茂貴
- Organizer
  第３３回日本薬学会九州支部大会
- Place of Presentation
  鹿児島市
- Year and Date
  2016-12-03
- Data Source
  KAKENHI-PROJECT-15H04633
[Presentation] N2-フェニル置換グアノシン誘導体によるPhdG/GC3重鎖塩基対特異性の向上2016
- Author(s)
  宮﨑芽依、谷口陽祐、佐々木茂貴
- Organizer
  第３３回日本薬学会九州支部大会
- Place of Presentation
  鹿児島
- Year and Date
  2016-12-03
- Data Source
  KAKENHI-PROJECT-26670056
[Presentation] 8-Oxoguanosine選択的なDNAポリメラーゼ基質としての非天然ヌクレオチドの開発2016
- Author(s)
  菊川誉也、谷口陽祐、佐々木茂貴
- Organizer
  日本薬学会第１３６回年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-26
- Data Source
  KAKENHI-PROJECT-24689006
[Presentation] Pinpoint modification of 6-NH2 of the adenine in RNA by the functionality transfer oligonucleotides and its impact on reverse-transcription and translation2016
- Author(s)
  Ikuya Oshiro, Daichi Jitsuzaki, Takuya Matsumoto, Yosuke Taniguchi and Shigeki Sasaki
- Organizer
  第43回国際核酸化学シンポジウム
- Place of Presentation
  熊本
- Year and Date
  2016-09-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04633
[Presentation] クロスリンク核酸によるmRNAの化学修飾と翻訳への影響2016
- Author(s)
  菊田健司，谷口陽祐，佐々木茂貴
- Organizer
  第42回反応と合成の進歩シンポジウム
- Place of Presentation
  静岡
- Year and Date
  2016-11-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04633
[Presentation] 塩基・部位特異的RNA化学修飾能を持つ官能基転移核酸による遺伝情報制御法の開発2016
- Author(s)
  大城郁也、實崎大地、松本卓也、谷口陽祐、佐々木茂貴
- Organizer
  日本薬学会第１３６回年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-26
- Data Source
  KAKENHI-PROJECT-15H04633
[Presentation] ＲＮＡの２’位水酸基を配列特異的に修飾する人工核酸の開発2016
- Author(s)
  高崎隼颯、羽田野友里恵、谷口陽祐、佐々木茂貴
- Organizer
  第５３回化学関連支部合同九州大会
- Place of Presentation
  北九州市
- Data Source
  KAKENHI-PROJECT-15H04633
[Presentation] Non-natural nucleoside derivatives for selective stabilization of the antiparallel triplex DNA with multiple inversion sites2016
- Author(s)
  Hidenori Okamura, Yosuke Taniguchi andShigeki Sasaki
- Organizer
  The First A3 Roundtable Meeting on Chemical Probe Research Hub
- Place of Presentation
  福岡
- Year and Date
  2016-09-22
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05100
[Presentation] アンチパラレル型3本鎖DNA形成可能な擬シチジン誘導体の開発と遺伝子発現制御法への展開2016
- Author(s)
  谷口陽祐、岡村秀紀、佐々木茂貴
- Organizer
  日本核酸医薬学会第2回年会
- Place of Presentation
  東京
- Year and Date
  2016-11-15
- Invited
- Data Source
  KAKENHI-PROJECT-16H05100
[Presentation] 非天然型3本鎖DNA形成可能な擬シチジン誘導体の開発とアンチジーン核酸医薬の創製2016
- Author(s)
  谷口陽祐，岡村秀紀，佐々木茂貴
- Organizer
  第３４回メディシナルケミストリーシンポジウム
- Place of Presentation
  筑波
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-16H05100
[Presentation] 鎖内クロスリンク反応を用いたi-motifの安定化2015
- Author(s)
  菊田健司、朴海順、John Brazier、鬼塚和光、永次史、谷口陽祐、佐々木茂貴
- Organizer
  第５2回化学関連支部合同九州大会
- Place of Presentation
  北九州市
- Year and Date
  2015-06-27
- Data Source
  KAKENHI-PROJECT-15H04633
[Presentation] ＲＮＡの２’位水酸基を修飾する官能基転移核酸の開発2015
- Author(s)
  高崎隼颯、羽田野友里恵、谷口陽祐、佐々木茂貴
- Organizer
  第３２回日本薬学会九州支部大会
- Place of Presentation
  延岡
- Year and Date
  2015-11-28
- Data Source
  KAKENHI-PROJECT-15H04633
[Presentation] Development of the 8-Halogenated-7-deazadG as an 8-Oxo-dG Analogue for the inhibition of their repair enzymes2015
- Author(s)
  Yosuke Taniguchi
- Organizer
  The 1st HU-TMU-KU Joint Symposium for Pharmaceutical Sciences、
- Place of Presentation
  札幌
- Year and Date
  2015-08-29
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24689006
[Presentation] 金属応答性ピリミジン型機能性核酸を用いたアデニン選択的RNA修飾法の開発2015
- Author(s)
  大城郁也、實崎大地、西本篤史、鬼塚和光、谷口陽祐、佐々木茂貴
- Organizer
  第２５回万有福岡シンポジウム
- Place of Presentation
  福岡
- Year and Date
  2015-05-16
- Data Source
  KAKENHI-PROJECT-15H04633
[Presentation] Synthesis of novel pseudocytidine derivatives for the selective recognition of CG base pairs in triple-helix DNA2015
- Author(s)
  Hidenori Okamura, Yosuke Taniguchi, Shigeki Sasaki
- Organizer
  PACIFICHEM2015
- Place of Presentation
  ハワイ
- Year and Date
  2015-12-15
- Data Source
  KAKENHI-PROJECT-24689006
[Presentation] Recognition and discrimination between 8-oxo-2'deoxyguanosin and 2'deoxyguanosine in DNA using the adenosine-1,3-diazaphenoxazine nucleoside derivatives2015
- Author(s)
  Yosuke Taniguchi,Yoshiya Kikukawa, Shigeki Sasaki
- Organizer
  PACIFICHEM2015
- Place of Presentation
  ハワイ
- Year and Date
  2015-12-15
- Data Source
  KAKENHI-PROJECT-24689006
[Presentation] Synthesis and evaluationof 8-oxo-2'-deoxyguanosine analogues as the novel binding compound for DNArepair enzyme2015
- Author(s)
  Mayuko Wada, Yizhen Yin,Shigeki Sasaki, Yosuke Taniguchi
- Organizer
  第４２回国際核酸化学シンポジウム
- Place of Presentation
  姫路
- Year and Date
  2015-09-23
- Data Source
  KAKENHI-PROJECT-24689006
[Presentation] ＧＣ塩基対に強く結合可能な人工核酸の開発2015
- Author(s)
  宮﨑芽依、谷口陽祐、松枝望、佐々木茂貴
- Organizer
  第３２回日本薬学会九州支部大会
- Place of Presentation
  宮﨑
- Year and Date
  2015-11-28
- Data Source
  KAKENHI-PROJECT-26670056
[Presentation] 3本鎖DNA中のCG塩基対を選択的に認識する擬シチジン誘導体の合成と機能評価2015
- Author(s)
  岡村秀紀、谷口陽祐、佐々木茂貴
- Organizer
  第１３回次世代を担う有機化学シンポジウム
- Place of Presentation
  立命館大学
- Year and Date
  2015-05-22
- Data Source
  KAKENHI-PROJECT-24689006
[Presentation] The effect ofintra-strand cross-link formation on the stability of DNA i-motif2015
- Author(s)
  Kenji Kikuta, PiaoHaishun, John Brazier, Kazumitsu Onizuka, Fumi Nagatsugi, Yosuke Taniguchi,Shigeki Sasaki
- Organizer
  第４２回国際核酸化学シンポジウム
- Place of Presentation
  姫路
- Year and Date
  2015-09-23
- Data Source
  KAKENHI-PROJECT-15H04633
[Presentation] Development of adenosine derivatives modified with phenoxazine unit for the recognition of 8-oxo-2'-deoxyguanosine in DNA2015
- Author(s)
  Yosuke Taniguchi
- Organizer
  The 6th Japanese-Sino Symposium on Organic Chemistry for Young Scientists
- Place of Presentation
  仙台
- Year and Date
  2015-09-06
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24689006
[Presentation] 酸化損傷塩基検出を目指したプリンヌクレオチド誘導体の合成と機能評価2015
- Author(s)
  菊川誉也、谷口陽祐、佐々木茂貴
- Organizer
  第４５回複素環化学討論会
- Place of Presentation
  早稲田大学
- Year and Date
  2015-11-19
- Data Source
  KAKENHI-PROJECT-24689006
[Presentation] 遺伝子修復酵素特異的結合を目指した酸化損傷塩基類似体の開発2015
- Author(s)
  谷口陽祐、尹貽貞、和田真由子、佐々木茂貴
- Organizer
  日本ケミカルバイオロジー学会第10回年会
- Place of Presentation
  東北大学
- Year and Date
  2015-06-10
- Data Source
  KAKENHI-PROJECT-24689006
[Presentation] DNA修復酵素に対する結合を目指した酸化損傷塩基類似体の合成と機能評価2015
- Author(s)
  和田真由子、佐々木茂貴、谷口陽
- Organizer
  第９回バイオ関連化学シンポジウム
- Place of Presentation
  熊本
- Year and Date
  2015-09-10
- Data Source
  KAKENHI-PROJECT-24689006
[Presentation] 鎖内クロスリンク形成によるi-motifの安定化2015
- Author(s)
  菊田健司、朴海順、John Brazier、鬼塚和光、永次史、谷口陽祐、佐々木茂貴
- Organizer
  第９回バイオ関連化学シンポジウム
- Place of Presentation
  熊本
- Year and Date
  2015-09-10
- Data Source
  KAKENHI-PROJECT-15H04633
[Presentation] 非天然型3本鎖ＤＮＡ形成を可能にする人工核酸の合成とアンチジーン法への応用2015
- Author(s)
  谷口陽祐、岡村秀紀、佐々木茂貴
- Organizer
  日本核酸医薬学会第1回年会
- Place of Presentation
  京都
- Year and Date
  2015-11-30
- Data Source
  KAKENHI-PROJECT-24689006
[Presentation] CpGアイランド特異的に結合する人工核酸の開発2014
- Author(s)
  松枝望、谷口陽祐、佐々木茂貴
- Organizer
  日本薬学会第１３４回年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-24689006
[Presentation] CG塩基対を安定かつ選択的に認識可能なN2-修飾イソシチジン誘導体の合成と3本鎖形成能の評価2014
- Author(s)
  岡村秀紀、谷口陽祐、佐々木茂貴
- Organizer
  日本薬学会第１３４回年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-24689006
[Presentation] 2-aminoAdapによるDNA中の8-oxodG検出法の開発2013
- Author(s)
  谷口陽祐、深堀慶太郎、古賀洋平、佐々木茂貴
- Organizer
  日本ケミカルバイオロジー第８回年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24659047
[Presentation] 2-aminoAdapの合成とDNA中の8-oxodG認識能の評価2013
- Author(s)
  谷口陽祐
- Organizer
  薬学会第１３３回年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24659047
[Presentation] CpGアイランドを標的とした人工核酸の開発2013
- Author(s)
  松枝望、谷口陽祐、佐々木茂貴
- Organizer
  第30回日本薬学会九州支部大会
- Place of Presentation
  長崎
- Data Source
  KAKENHI-PROJECT-24689006
[Presentation] 3本鎖DNAの安定化を目指した新規1',1'-二置換ヌクレオシドの開発2013
- Author(s)
  冨崎瑛、谷口陽祐、岡村秀紀、佐々木茂貴
- Organizer
  第２５回若手研究者のためのセミナー
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24689006
[Presentation] CG塩基対を選択的に認識可能なN-修飾イソシチジン誘導体の合成と3本鎖形成能の評価2013
- Author(s)
  岡村秀紀、谷口陽祐、佐々木茂貴
- Organizer
  第２５回若手研究者のためのセミナー
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24689006
[Presentation] 8-oxodGに対する塩基選択性の向上を目指したAdap誘導体の開発2013
- Author(s)
  菊川誉也、谷口陽祐、深堀慶太郎、佐々木茂貴
- Organizer
  第30回日本薬学会九州支部大会
- Place of Presentation
  長崎
- Data Source
  KAKENHI-PROJECT-24659047
[Presentation] N-(Guanidinoethyl)-2'-deoxy-5-methylisocytidine exhibits selective recognition of the CG inversion site for the formation of anti-parallel triplex DNA2013
- Author(s)
  Hidenori Okamura, Yosuke Taniguchi, and Shigeki Sasaki
- Organizer
  ＡＣＭＳ２０１３
- Place of Presentation
  沖縄
- Data Source
  KAKENHI-PROJECT-24689006
[Presentation] Synthesesand Evaluation of Anti-parallel Triplex Formation of 1’-Phenyl-2’-ThymineNucleoside Analogues for the Application to the Antigene Strategy2013
- Author(s)
  Yosuke Taniguchi,Akira Tomizaki, Hidenori Okamura, Syohei Misumi, Tomoko Takaki, Naoto Ishibashi and Shigeki Sasaki
- Organizer
  ＡＩＭＥＣＳ２０１３
- Place of Presentation
  台湾
- Data Source
  KAKENHI-PROJECT-24689006
[Presentation] CG 塩基対を選択的に認識可能なN- グアニジノエチルイソシチジンの合成と3 本鎖DNA 形成能の評価2013
- Author(s)
  岡村秀紀、谷口陽祐、佐々木茂貴
- Organizer
  第５０回化学関連支部合同九州大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24689006
[Presentation] Fluorescence detectionof 8-oxo-2'-deoxyguanosine in DNA by Adap-masked ODN probe2012
- Author(s)
  Yosuke Taniguchi
- Organizer
  第３９回国際核酸化学シンポジウム
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-24659047
[Presentation] オルト位にメチル基を持つWNA誘導体によるDNA鎖交換反応促進作用の機構解明2012
- Author(s)
  谷口陽祐
- Organizer
  第6回バイオ関連化学シンポジウム
- Place of Presentation
  北海道大学
- Year and Date
  2012-09-07
- Data Source
  KAKENHI-PROJECT-24689006
[Presentation] Recognition and Fluorescence Detection of 8‐Oxo‐2’‐Deoxyguanosine in DNA By Adenosine‐1,3‐Diazaphenoxazine Derivative2012
- Author(s)
  Yosuke Taniguchi
- Organizer
  XX International Round Table on Nucleosides, Nucleotides and Nucleic Acids
- Place of Presentation
  Montreal, CANADA
- Data Source
  KAKENHI-PROJECT-24659047
[Presentation] DNA中の8-oxodG認識人工核酸Adap搭載プローブによる蛍光検出法の開発2012
- Author(s)
  谷口陽祐
- Organizer
  日本ケミカルバイオロジー学会第７回年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24659047
[Presentation] 3本鎖DNA形成を志向した新規二置換ヌクレオシドアナログの開発2010
- Author(s)
  高木智子、谷口陽祐、石橋直人、佐々木茂貴
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Year and Date
  2010-03-29
- Data Source
  KAKENHI-PROJECT-20790013
[Presentation] 高感度遺伝子検出を目指した銅錯体-DNAプローブの創製2010
- Author(s)
  谷口陽祐
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Year and Date
  2010-03-29
- Data Source
  KAKENHI-PROJECT-20790013
[Presentation] DESIGN OF NEW NUCLEOSIDE ANALOGS FOR THE FORMATION OF STABLE TRIPLEX DNA AND ITS APPLICATION TO ANTIGENE INHIBITION2009
- Author(s)
  Yosuke Taniguchi
- Organizer
  Joint Symposium of 5th Annual Meeting of Oligonucleotide Therapeutics Society and the 19th Antisense Symposium
- Place of Presentation
  Fukuoka
- Year and Date
  2009-11-04
- Data Source
  KAKENHI-PROJECT-20790013
[Presentation] 非天然型3本鎖DNA形成を可能にするW字型ビシクロ核酸誘導体の合成と機能評価2009
- Author(s)
  谷口陽祐
- Organizer
  第35回反応と合成の進歩シンポジウム
- Place of Presentation
  金沢
- Year and Date
  2009-11-17
- Data Source
  KAKENHI-PROJECT-20790013
[Presentation] 小さな認識塩基をもつW字型人工核酸の合成と3本鎖形成能の評価2009
- Author(s)
  内田祐子、谷口陽祐、青木絵里子、東郷美枝子、佐々木茂貴
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Year and Date
  2009-03-27
- Data Source
  KAKENHI-PROJECT-20790013
[Presentation] DESIGN OF NEW NUCLEOSIDE ANALOGS FOR THE FORMATION OF STABLE TRIPLEX DNA AND ITS APPLICATION TO ANTIGENE INHIBITION2009
- Author(s)
  Yosuke Taniguchi, Yuko Uchida, Tomoko Takaki, Tamer Mohamed Nasr Hefni, Shigeki Sasaki
- Organizer
  Joint Symposium of 5th Annual Meeting of Oligonucleotide Therapeutics Society and the 19th Antisense Symposium in Fukuoka, Japan
- Place of Presentation
  Fukuoka
- Year and Date
  2009-11-04
- Data Source
  KAKENHI-PROJECT-20790013
[Presentation] Development of novel disustituted nucleoside analogs for the formation of triplex DNA2009
- Author(s)
  Tomoko Takaki, Yosuke Taniguchi, Naoto Ishibashi, Shigeki Sasaki
- Organizer
  Asian Federation for Pharmaceutical Sciences 2009
- Place of Presentation
  Fukuoka
- Year and Date
  2009-10-17
- Data Source
  KAKENHI-PROJECT-20790013
[Presentation] 非天然型3本鎖DNA形成を可能にするW字型ビシクロ核酸誘導体の合成と機能評価2009
- Author(s)
  谷口陽祐、内田裕子、高木智子、Tamer Nasr、青木絵里子、佐々木茂貴
- Organizer
  第35回反応と合成の進歩シンポジウム
- Place of Presentation
  金沢(口頭発表)
- Year and Date
  2009-11-17
- Data Source
  KAKENHI-PROJECT-20790013
[Presentation] 異なる長さのリンカーを有するクロスリンク核酸の合成とその機能評価2009
- Author(s)
  谷口陽祐
- Organizer
  日本薬学会第129年会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2009-03-26
- Data Source
  KAKENHI-PROJECT-17209001
[Presentation] Evaluation of the antisense effect of PEGylated oligodeoxynucleotides containing intelligent nucleoside analogues2009
- Author(s)
  Yosuke Taniguchi
- Organizer
  The 6th International symposium on Nucleic Acid Chemistry
- Place of Presentation
  Gifu
- Year and Date
  2009-09-27
- Data Source
  KAKENHI-PROJECT-20790013
[Presentation] 異なる長さのリンカーを有するクロスリンク核酸の合成とその機能評価2008
- Author(s)
  谷口陽祐
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20790013
[Presentation] 機能性核酸を導入したアンチセンス核酸によるサイズの異なるタンパク質の発現2008
- Author(s)
  谷口陽祐
- Organizer
  第18回アンチセンスシンポジウム
- Place of Presentation
  岐阜
- Year and Date
  2008-09-28
- Data Source
  KAKENHI-PROJECT-20790013
[Presentation] 遺伝子特異的人工核酸のデリバリーシステムを用いた細胞内反応への展開-化学反応による遺伝子修飾および修復を目指して2008
- Author(s)
  佐々木茂貴、永次史、井本修平、谷口陽祐、鬼塚和光
- Organizer
  第57回高分子討論会
- Place of Presentation
  大阪市立大学(大阪市)
- Data Source
  KAKENHI-PROJECT-17209001
[Presentation] Formation of a stable triplex incorporating a CG interrupting site by a new WNA derivative containing 3-aminopyrazole as a nucleobase2008
- Author(s)
  Yuko Uchida, Yosuke Taniguchi, Eriko Aoki, Mieko Togo, Shigeki Sasaki
- Organizer
  Joint Symposium of the 18th International Roundtable on Nucleosides, Nucleotides, and Nucleic Acids and the 35th International Symposium on Nucleic Acids Chemistry
- Place of Presentation
  Kyoto
- Year and Date
  2008-09-08
- Data Source
  KAKENHI-PROJECT-20790013
[Presentation] Design of S-vinlyated 6-thioguanosine as a specific modifier of cytidine2008
- Author(s)
  K. Onizuka, Y.Taniguchi, S. Sasaki
- Organizer
  14th Symposium on Chemistry of Nucleic Acid Components
- Place of Presentation
  Cesky Krumlov, Czech
- Data Source
  KAKENHI-PROJECT-17209001
[Presentation] 生体模倣2核銅錯体による化学発反応を利用した遺伝子検出プローブの開発2008
- Author(s)
  谷口陽祐
- Organizer
  日本ケミカルバイオロジー研究会第3回年会
- Place of Presentation
  学術総合センター(東京)
- Year and Date
  2008-05-19
- Data Source
  KAKENHI-PROJECT-17209001
[Presentation] 機能性核酸を導入したアンチセンス核酸によるサイズの異なるタンパク質の発現2008
- Author(s)
  谷口陽祐
- Organizer
  第18回アンチセンスシンポジウム
- Place of Presentation
  岐阜大学医学部記念会館
- Year and Date
  2008-11-17
- Data Source
  KAKENHI-PROJECT-17209001
[Presentation] 生体模倣2核銅錯体による化学発光を利用した遺伝子検出プローブの開発2008
- Author(s)
  谷口陽祐
- Organizer
  第3回ケミカルバイオロジー研究会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20790013
[Presentation] Syntheses and properties of low-polarity shape mimics of 8-oxopurines2007
- Author(s)
 谷口陽祐
- Organizer
 The 5^<th> International Symposium on Nucleic Acids Chemistry
- Place of Presentation
 東京
- Data Source
 KAKENHI-PROJECT-19890147
[Presentation] 遺伝子発現制御を目指した機能性核酸の展開2007
- Author(s)
  谷口陽祐
- Organizer
  万有福岡シンポジウム第1回若手交流合宿セミナー
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-19890147
[Presentation] 8位酸化型プリン塩基に構造が類似した核酸誘導体の性質2007
- Author(s)
  谷口陽祐
- Organizer
  第22回生体機能関連化学シンポジウム
- Place of Presentation
  仙台
- Year and Date
  2007-09-27
- Data Source
  KAKENHI-PROJECT-19890147
[Presentation] 8-0x0dG選択性向上を目指したAdap誘導体の開発
- Author(s)
  菊川誉也、谷口陽祐、深堀慶太郎、佐々木茂貴
- Organizer
  日本薬学会第134回年会
- Data Source
  KAKENHI-PROJECT-24659047
[Presentation] The Fluorescent Probe for 8-oxo-Guanosine in RNA
- Author(s)
  Yohei Koga, Yosuke Taniguchi, Shigeki Sasaki
- Organizer
  第39回国際核酸化学シンポジウム
- Data Source
  KAKENHI-PROJECT-24659047
[Presentation] DNA中の8-oxodG認識人工核酸Adap搭載プローブによる蛍光検出法の開発
- Author(s)
  谷口陽祐、古賀洋平、深堀慶太郎、佐々木茂貴
- Organizer
  日本ケミカルバイオロジー学会第7回年会
- Data Source
  KAKENHI-PROJECT-24659047
[Presentation] RNA中の8-オキソグアノシン認識及び検出を目指した人工核酸の開発
- Author(s)
  古賀洋平、谷口陽祐、佐々木茂貴
- Organizer
  第6回バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PROJECT-24659047
[Presentation] Specific recognition of CG base pairs by novel pseudo-cytidine derivatives in antiparallel DNA triplexes
- Author(s)
  Hidenori Okamura, Yosuke Taniguchi, Shigeki Sasaki
- Organizer
  第４１回国際核酸化学シンポジウム
- Place of Presentation
  福岡
- Year and Date
  2014-11-05 – 2014-11-07
- Data Source
  KAKENHI-PROJECT-24689006
[Presentation] Development of triplex-forming oligonucleotide having artificial nucleoside analogues to inhibit the gene expression as an antigene strategy
- Author(s)
  Yosuke Taniguchi, Hidenori Okamura, Shigeki Sasaki
- Organizer
  DPhG Jahrestagung 2014/ Annual meeting,
- Place of Presentation
  Frankfurt, Deutsche
- Year and Date
  2014-09-24 – 2014-09-26
- Invited
- Data Source
  KAKENHI-PROJECT-24689006
[Presentation] Selective CG base pair recognition by pyrimidine nucleosideanalogues in all four flanking pairs within antiparallel triple helix DNA
- Author(s)
  Hidenori Okamura, Yosuke Taniguchi, Shigeki Sasaki
- Organizer
  XXI Round Table on Nucleosides, Nucleotides and Nucleic Acids
- Place of Presentation
  POZNAN, POLAND.
- Year and Date
  2014-08-24 – 2014-08-28
- Data Source
  KAKENHI-PROJECT-24689006
[Presentation] 8-oxodGに対する塩基選択性の向上を目指したAdap誘導体の開発
- Author(s)
  菊川誉也、谷口陽祐、深堀慶太郎、佐々木茂貴
- Organizer
  第30回日本薬学会九州支部大会
- Data Source
  KAKENHI-PROJECT-24659047
[Presentation] Fluorescence detectionof 8-oxo-2'-deoxyguanosine in DNA by Adap-masked ODN probe
- Author(s)
  Yosuke Taniguchi, Yohei Koga, Keitaro Fukabori, Shigeki Sasaki
- Organizer
  第39回国際核酸化学シンポジウム
- Data Source
  KAKENHI-PROJECT-24659047
[Presentation] 2-aminoAdapによるDNA中の8-oxodG検出法の開発
- Author(s)
  谷口陽祐、深堀慶太郎、古賀洋平、佐々木茂貴
- Organizer
  日本ケミカルバイオロジー第8回年会
- Data Source
  KAKENHI-PROJECT-24659047
[Presentation] CG塩基対を選択的に認識可能な擬シチジン誘導体の合成と3本鎖形成能評価
- Author(s)
  岡村秀紀、谷口陽祐、佐々木茂貴
- Organizer
  アンチセンスシンポジウム・遺伝子・デリバリーシンポジウム２０１４
- Place of Presentation
  東京
- Year and Date
  2014-09-08 – 2014-09-09
- Data Source
  KAKENHI-PROJECT-24689006
[Presentation] 8-オキソグアノシンの特異的認識を目指したAdap誘導体の合成及び機能評価
- Author(s)
  深堀慶太郎、谷口陽祐、古賀洋平、佐々木茂貴
- Organizer
  第38回反応と合成の進歩シンポジウム
- Data Source
  KAKENHI-PROJECT-24659047
[Presentation] 2-aminoAdapの合成とDNA中の8-oxodG認識能の評価
- Author(s)
  谷口陽祐、深堀慶太郎、古賀洋平、佐々木茂貴
- Organizer
  薬学会第133回年会
- Data Source
  KAKENHI-PROJECT-24659047
[Presentation] CG障害部位を選択的に認識する擬シチジン誘導体の合成と3本鎖形成能の評価
- Author(s)
  岡村秀紀、谷口陽祐、佐々木茂貴
- Organizer
  日本薬学会第１３５回年会
- Place of Presentation
  神戸
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-24689006
[Presentation] Recognition and Fluorescence Detection of 8‐Oxo‐2'‐Deoxyguanosine in DNA By Adenosine‐1,3‐Diazaphenoxazine Derivative
- Author(s)
  Yosuke Taniguchi, Yohei Koga, Keitaro Fukabori, Ryota Kawaguchi and Shigeki Sasaki
- Organizer
  XX International Round Table on Nucleosides, Nucleotides and Nucleic Acids
- Data Source
  KAKENHI-PROJECT-24659047

1. SASAKI Shigeki (10170672)

# of Collaborated Projects: 2 results

# of Collaborated Products: 51 results
2. NAKAGAWA Osamu (90380691)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
3. TSUZUKI Teruhisa (40155429)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. NAGATSUGI Fumi (90208025)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
5. FUCHI Yasufumi (40748795)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. Miyata Kanjiro (50436523)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 劉学瑩 (30777470)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 藤加珠子 (90342732)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 林光太朗 (00780660)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. MASUMURA Kenichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 和泉自泰

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 鬼塚和光

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

TANIGUCHI YOSUKE 谷口 陽祐

TANIGUCHI Yosuke 谷口 陽祐

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3本鎖DNA形成を基軸とした人工核酸の開発と遺伝子発現コントロール技術への新展開Principal Investigator

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Development of advanced nanomedicines for brain-targeted oligonucleotide delivery

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Development of artificial nucleoside analogues for the duplex DNA recognition, and antigene oligonucleotidesPrincipal Investigator

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Development of novel gene detection method using artificial nucleic acid capable of recognizing damaged basesPrincipal Investigator

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Examination of oligonucleotide therapeutics based on the triplex DNA formation by artificial oligonucleotidePrincipal Investigator

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Chemically reactive oligonucleotides for site-specific modification of RNA and artificial RNA editing

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Development of CpG island binding molecule based on artificial dinucleotidePrincipal Investigator

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Development of the recognition molecule for 8-oxo-rG in RNAPrincipal Investigator

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Development of antigene strategy by triplex forming oligonucleotides having artificial nucleoside analoguesPrincipal Investigator

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Development of the nucleoside analogs to harmonize with in vivo molecular functionPrincipal Investigator

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タンパク質との機能融合を目指したゲノム標的機能性人工核酸の開発Principal Investigator

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Development of Genome-Targeting Molecules with Ability of Chemical Reactivity and Application to Intelligent Nano-Medicine

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[Book] 核酸医薬・mRNA医薬の製造分析の基礎と基盤技術開発2023

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TANIGUCHI YOSUKE 谷口陽祐

TANIGUCHI Yosuke 谷口陽祐