KIURA Katuyuki 木浦勝行

Researcher Number	10243502
Other IDs
Affiliation (Current)	2025: 岡山大学, 医学部, 客員研究員
Affiliation (based on the past Project Information) *help	2023 – 2024: 岡山大学, 医学部, 客員研究員 2011 – 2022: 岡山大学, 大学病院, 教授 2012: 岡山大学, 岡山大学病院, 教授 2007 – 2010: Okayama University, 大学院・医歯薬学総合研究科, 准教授 2008: 岡山大学, 医歯薬学総合研究科, 准教授 … More 2006: 岡山大学, 大学院・医歯薬学総合研究科, 助教授 2006: Okayama University, Okayama Graduate School of Medicine, Dentistry and Pharmaceutica Sciences, Associate Professor, 大学院医歯薬学総合研究科, 助教授 2005: 岡山大学, 医歯薬学総合研究科, 助教授 2004: 岡山大学, 大学院・医歯学総合研究科, 講師 2004: Okayama University Med Sch, 2nd Dept of Med, Assistant Professor, 大学院医歯薬総合研究科, 講師 2003 – 2004: Okayama University, Hospital, Assistant Professor, 医学部・歯学部附属病院, 講師 2000 – 2003: 岡山大学, 医学部, 講師 2002: 岡山大学, 医学部附属病院, 講師 2000 – 2001: Okayama University Medical School, Lecturer, 医学部・附属病院, 講師 1998 – 1999: 岡山大学, 医学部, 助手 1996 – 1999: 岡山大学, 医学部・附属病院, 助手 1998: Okayama University Medical School.Okayama University Hospital.Assistant, 医学部附属病院, 助手 Less
Review Section/Research Field	Principal Investigator Respiratory organ internal medicine / 内科学一般 / Basic Section 53030:Respiratory medicine-related Except Principal Investigator Respiratory organ internal medicine / Basic Section 53030:Respiratory medicine-related / Hematology / Medium-sized Section 53:Organ-based internal medicine and related fields / Biological Sciences / Tumor therapeutics / Radiation science
Keywords	Principal Investigator 肺癌 / EGFR / NNK / 上皮成長因子受容体 / 遺伝子改変マウス / 非小細胞肺癌 / 呼吸器の腫瘍 / 臨床呼吸器学 / EGFR変異 / second malignancy … More / lung cancer / ras / cisplatin / J mouse / A / MAPK / AKT / p16 / SBC-3 / EBC-2 / CD34 / p53 / Negative Signal / everolimus / afatinib / EGFR遺伝子改変マウス / 肺腺癌 / ゲフィチニブ / Ad- SGE-REIC / 遺伝子治療 / ウィルスベクター / ＥＧＦＲ変異 / 腫瘍免疫療法 / 腫瘍免疫 / PD-1 / 抗腫瘍免疫療法 / REIC / レーザーマイクロダイセクション / Kinase遺伝子発現解析 / 次世代シーケンサー / 特発性肺線維症 / 肺線維症 / 内科 / EGFR肺癌 / 肺癌幹細胞 / 非小細胞癌 / 遺伝子改変マウスモデル / 癌幹細胞 / Li-Fraumeni syndrome / Early onset / Lung Cancer / Li-Faumeni症候群 / Li Fraumeni症候群 / 若年発症 / Killer Inhibitory Receptors / NK Cell Receptors / HLA Class Molecules / Natural Killer Cells / NKBI / NK細胞receptor / Class I / NKB1 / EB6 / GL183 / NK細胞Receptor / Negative signal / ClassI / NK細胞リセプター / HLA ClassI分子 / KIR / NK細胞レセプター / HLA Class I 分子 / NK細胞 / vandetanib / gefetinib / PD-L1抗体 / PD-1抗体 / PNA LNA PCR-Clamp法 / EGFR遺伝子変異陽性肺癌 / 抗PD-L1抗体 / 抗PD-１抗体 / 相関 / 手術検体 / EGFR阻害薬 / 免疫染色 / Egfr遺伝子改変マウス / EGFR遺伝子変異 / PD-L1 / (1)含鉄蛋白質 / 体内被曝 / 含鉄蛋白 / ラット / プリミティブマントル正規化微量原素パターン / 発癌 / 鉄 / 生体内被曝 / ラジウム / 悪性中皮腫 / 非閉塞性肺疾患癌 / mTOR阻害薬 / BIBW2552 / JAK1/2阻害薬 / ｍTOR阻害薬 / 用量依存性 / gefitinib / AZD1480 / everolims / Ogg1ホモノックアウトマウス / bevacizumab / cetuximab / JAK-1/2 inhibitors / everolimus (mTOR阻害薬), / ヴィノレルビン / L858R / 動物実験モデル / ジェムサイタビン / ドセタキセル / 上皮成長因子受容遺伝子異 / SP-C / 非喫煙 / ZD6474 / 分子標的化学予防 / 血管内皮細胞成長因子受容体 / バンデタニブ / 化学予防 / 非喫煙者 / 腺癌 … More Except Principal Investigator 肺癌 / EGFR変異 / 非小細胞肺癌 / EGFR / G-CSF / ジーンターゲティング / 腫瘍微小環境 / 非小細胞癌 / 腫瘍免疫 / GVHD / 遺伝子改変マウス / 肺腺癌 / 遺伝子変異 / 発癌 / NK細胞 / 薬剤耐性 / Rad51 / 急性GVHD / 末梢血幹細胞移植 / 腫瘍免疫療法 / EGFR－TKI / EGFR肺癌 / 抗腫瘍免疫 / CD8陽性T細胞 / persister癌細胞 / 2型肺胞上皮細胞 / Oct４ / ２型肺胞上皮細胞 / Oct4 / 癌幹細胞 / persisterがん細胞 / persister / VEGR2 / PD-1 / sister chromatid exchanges / Fanconi anemia / Rad51 paralogs / DT 40 cells / DNA repair / homologous recombination / XRCC3 / Rad52 / Rad51ファミリー / 相同組み換え / 複製後修復 / 相同組替え / 姉妹染色分体交換 / BLMヘリケース / ファンコニ貧血 / Rad51パラログ / DT40細胞 / 相同DNA組み換え / DNA修復 / Natural killer cell / T cell modulation / Mobilization / Cytokine / Peripheral blood stem cell / Hematopoietic stem cell / IL-10 / インターフェロンγ / TNF-α / CD34 / CFU-GM / 単球 / IL-4 / IFN-γ / VLA-4 / 同種末梢血幹細胞移植 / T細胞機能修飾 / 動員 / サイトカイン / 末梢血幹細胞 / 造血幹細胞 / インターロイキン6（IL-6） / EGFR-TKI / EGFR遺伝子変異陽性非小細胞肺がん / チロシンキナーゼ阻害薬 / IL-6 / 肺がん幹細胞 / 胎仔の器官培養 / EGFRチロシンリン酸化酵素阻害薬 / マウスEgfr遺伝子改変マウス / EGFRチロシンリン酸化酵素阻害剤 / EGFR遺伝子変異 / マウスEGFR遺伝子改変マウス / EGFR遺伝子改変マウス / 器官培養 / EGFR遺伝子変異改変マウス / BASCs / 血管新生 / STAT3 / JAK2 / mTOR / 肺アスペルギローマ / 真菌症 / ラジオ波治療 / アスペルギローマ / ラジオ波焼灼療法 / (5)メチル化DNA / メチル化DNA / 血清遊離DNA / 早期診断 / 塵肺 / 肺線維症 / 癌 / 重複癌 / Bcl-2 / LMP-1 / Epstein-Barr virus(EBV) / NKリンパ種 / P糖蛋白 / アポトーシス / latent membrane protein1 / エプスタイン・バーウィルス(EBV) / 鼻腔原発 / NK細胞リンパ腫 / ヌクレオチド除去修復 / DNA相同組換え / ドナーリンパ球輸注 / VNTR / 抹消血幹細胞採取 / 移植前治療 / 同種抹消血幹細胞移植 / 高年者白血病 / 相同DNA組み換え機構 / 肺ガン細胞株 / Rad51関連遺伝子群 / シスプラチン / RT-PCR / GRP-レセプター / サイトケラチン 19 / 末梢血混入腫瘍細胞 / 超大量化学療法 / purging / 肺小細胞癌 Less

Establishment of a mouse model of Oct4-positive lung cancer stem cells and development of innovative therapies to eradicate cancer stem cells
- Principal Investigator
  
  Ohashi Kadoaki
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 53:Organ-based internal medicine and related fields
- Research Institution
  Okayama University
persister癌細胞と腫瘍微小環境の双方を標的とした革新的腫瘍免疫療法の開発
- Principal Investigator
  
  大橋圭明
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Okayama University
Development of a curative treatment strategy for lung cancer using the persister cancer cell mouse model.
- Principal Investigator
  
  Ohashi Kadoaki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Okayama University
Development of innovative immunotherapy for lung cancer using tumor immune-activating gene REICPrincipal Investigator
- Principal Investigator
  
  Katsuyuki Kiura
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Okayama University
Comprehensive analysis of druggable tyrosine kinase in idiopathic interstitial pneumoniaPrincipal Investigator
- Principal Investigator
  
  Kiura Katsuyuiki
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Okayama University
Next generation lung cancer mice model for conquering cancer stemPrincipal Investigator
- Principal Investigator
  
  Kiura Katsuyuki
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Okayama University
Potential influence of interleukin-6 on the therapeutic effect of gefitinib in patients with advanced non-small cell lung cancer harbouring EGFR mutations
- Principal Investigator
  
  Hotta Katsuyuki
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor therapeutics
- Research Institution
  Okayama University
Basic study on combined modality therapy for advanced lung cancer harboring activated EGFR gene mutationPrincipal Investigator
- Principal Investigator
  
  KIURA Katsuyuki
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Okayama University
Effects of molecular-targeted drugs on nonsmoking-related lung cancer models
- Principal Investigator
  
  TAKIGAWA Nagio
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Kawasaki Medical School
Identification of stem cells from oncogenic mouse lungs by epithelial growth factor receptor gene mutation
- Principal Investigator
  
  SATO AKIKO
- Project Period (FY)
  2012 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Okayama University
Basic and clinical study of EGFR gene mutation-positive lung cancer using a genetically modified mousePrincipal Investigator
- Principal Investigator
  
  KIURA Katsuyuki
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Okayama University
A basic studyon malignant mesothelioma pathogenesis by internal radiation exposure of radium contained in the iron-containing proteinPrincipal Investigator
- Principal Investigator
  
  KIURA Katsuyuki
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Okayama University
Radiofrequency ablation for pulmonary aspergilloma
- Principal Investigator
  
  HIRAKI Takao
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Okayama University
Mechanism of progression from bronchioloalveolar carcinoma to invasive adenocarcinoma
- Principal Investigator
  
  TAKIGAWA Nagio
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Kawasaki Medical School
  Okayama University
上皮成長因子受容体遺伝子変異陽性肺癌の根治治療開発を目指した動物実験モデルの樹立Principal Investigator
- Principal Investigator
  
  木浦勝行
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Okayama University
Chemoprevention of Lung Cancer using Epidermal Growth Factor Receptor Transgenic MicePrincipal Investigator
- Principal Investigator
  
  KIURA Katsuyuki
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Okayama University
Mechanism of carcinogenesis from pulmonary atypical adenomatous hyperplasia to adenocarcinoma
- Principal Investigator
  
  TAKIGAWA Nagio
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Okayama University
Early detection of lung cancer using aberrant promoter hypermethylation in serum DNA from patients with silicosis
- Principal Investigator
  
  TABATA Masahiro
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Okayama University
Chemoprevention of second primary cancer in the patients with lung cancerPrincipal Investigator
- Principal Investigator
  
  KIURA Katsuyuki
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Okayama University
NK細胞白血病/リンパ腫の増殖機序と増殖抑制に関する研究
- Principal Investigator
  
  原田実根
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Hematology
- Research Institution
  Kyushu University
  Okayama University
Functional analysis of genes involved in maintenance of chromosome stability and homologous recombination
- Principal Investigator
  
  TAKATA Minoru
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kawasaki Medical School
Biological characteristics and genetic abnormalities in very, young patients with lung cancer (【less than or equal】30 years of age)Principal Investigator
- Principal Investigator
  
  KIURA Katsuyuki
- Project Period (FY)
  2000 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  OKAYAMA UNIVERSITY
ヒト癌細胞シスプラチン感受性決定因子としてのDNA損傷修復分子機構の解析
- Principal Investigator
  
  高田穣
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kyoto University
ヒト癌細胞のシスプラチン感受性決定因子としての相同組み換え関連遺伝子群の役割-ノックアウト細胞株と肺癌細胞株による検討-
- Principal Investigator
  
  TAKATA Minoru
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kyoto University
高年者白血病に対する同種抹消血幹細胞移植に関する基礎的臨床的研究
- Principal Investigator
  
  原田実根
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Okayama University
G-CSF-induced mobilization of peripheral blood stem cells trans-plantation and analysis of G-CSF-primed immunocompetent cells
- Principal Investigator
  
  HARADA Mine
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Hematology
- Research Institution
  OKAYAMA UNIVERSITY
肺小細胞癌の生物学的特性を利用する末梢血幹細胞移植に関する基礎的臨床的研究
- Principal Investigator
  
  HARADA Mine
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Okayama University
The Relationship between Mojor Histocompatibility Complex Class I Molccules and Natural Killer CellsPrincipal Investigator
- Principal Investigator
  
  KIURA Katsuyuki
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  Okayama University

[Book] Annual Review呼吸器20142014
- Author(s)
  木浦勝行
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-25670399
[Book] Annual Review呼吸器2014　治療の進歩 EGFR-TKIs耐性肺癌に対する新しい分子標的治療2014
- Author(s)
  木浦勝行
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-23390221
[Book] 【最新がん薬物療法学-がん薬物療法の最新知見-】がん薬物治療薬の作用機序　分子標的治療薬　低分子化合物　ALK融合タンパク質チロシンリン酸化酵素阻害薬2014
- Author(s)
  木浦勝行
- Publisher
  日本臨床(0047-1852)72巻増刊2 最新がん薬物療法学
- Data Source
  KAKENHI-PROJECT-23390221
[Book] 抗がん薬の臨床薬理Anti-cancer drugs and Pharmacology（[監修]相羽惠介）１｜受容体・シグナル伝達系阻害薬（小分子化合物）　１．HER阻害薬　２　Elrotinibを分担2013
- Author(s)
  木浦勝行
- Publisher
  南山堂
- Data Source
  KAKENHI-PROJECT-23390221
[Book] Therapy and Prognosis2009
- Author(s)
  Kiura K, Takigawa N, Segawa Y
- Total Pages
  609
- Publisher
  Springer, Methods of Cancer Diagnosis
- Data Source
  KAKENHI-PROJECT-18590851
[Book] Methods of Cancer Diagnosis, Therapy and Prognosis2009
- Author(s)
  Katsuyuki Kiura, Nagio Takigawa, Yoshihiko Segawa
- Total Pages
  609
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-18590851
[Book] Advanced Non-Small Cell Lung Carcinoma Acquired Resistance to Gefitinib (Methods of Cancer Diagnosis, Therapy and Prognosis : General Methods and Overviews, Lung Carcinoma and Prostate Carcinoma (Methods of Cancer Diagnosis, Therapy and Prognosis)2008
- Author(s)
  Kiura K, Takigawa N, Segawa Y
- Publisher
  Hayat, M. A. (EDT)
- Data Source
  KAKENHI-PROJECT-19590895
[Journal Article] CDK4/6 signaling attenuates the effect of epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors in EGFR-mutant non-small cell lung cancer2023
- Author(s)
  Hara Naofumi、Ichihara Eiki、Kano Hirohisa、Ando Chihiro、Morita Ayako、Nishi Tatsuya、Okawa Sachi、Nakasuka Takamasa、Hirabae Atsuko、Abe Masaya、Asada Noboru、Ninomiya Kiichiro、Makimoto Go、Fujii Masanori、Kubo Toshio、Ohashi Kadoaki、Hotta Katsuyuki、Tabata Masahiro、Maeda Yoshinobu、Kiura Katsuyuki
- Journal Title
  
  Translational Lung Cancer Research
  
  Volume: 12 Issue: 10 Pages: 2098-2112
- DOI
  10.21037/tlcr-23-99
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08179, KAKENHI-PROJECT-22K19529, KAKENHI-PROJECT-23K24339
[Journal Article] Low frequency of intracranial progression in advanced NSCLC patients treated with cancer immunotherapies2023
- Author(s)
  Kemmotsu N , Ninomiya K , Kunimasa K , IshinoT ,Nagasaki J , Otani Y , Michiue H ,Ichihara E ,Ohashi K ,Inoue T ,Tamiya M ,Sakai K ,Ueda Y , Dansako H ,Nishio K ,Kiura K , Date I ,Togashi Y
- Journal Title
  
  International Journal of Cancer
  
  Volume: 154(1) Issue: 1 Pages: 169-179
- DOI
  10.1002/ijc.34700
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16687, KAKENHI-PROJECT-21K09176, KAKENHI-PROJECT-22K19459, KAKENHI-PROJECT-22K19529, KAKENHI-PROJECT-22K15472, KAKENHI-PROJECT-23K24339
[Journal Article] PD-1 blockade augments CD8+ T cell dependent antitumor immunity triggered by Ad-SGE-REIC in Egfr-mutant lung cancer2023
- Author(s)
  Nakasuka Takamasa、Ohashi Kadoaki、Nishii Kazuya、Hirabae Atsuko、Okawa Sachi、Tomonobu Nahoko、Takada Kenji、Ando Chihiro、Watanabe Hiromi、Makimoto Go、Ninomiya Kiichiro、Fujii Masanori、Kubo Toshio、Ichihara Eiki、Hotta Katsuyuki、Tabata Masahiro、Kumon Hiromi、Maeda Yoshinobu、Kiura Katsuyuki
- Journal Title
  
  Lung Cancer
  
  Volume: 178 Pages: 1-10
- DOI
  10.1016/j.lungcan.2023.01.018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K23930, KAKENHI-PROJECT-19H03667, KAKENHI-PROJECT-23K14595, KAKENHI-PROJECT-22K19529, KAKENHI-PROJECT-22K20793, KAKENHI-PROJECT-23K24339
[Journal Article] Efficacy of gilteritinib in comparison with alectinib for the treatment of ALK-rearranged non-small cell lung cancer.2023
- Author(s)
  Ando C, Ichihara E, Nishi T, Morita A, Hara N, Takada K, Nakasuka T, Watanabe H, Kano H, Nishii K, Makimoto G, Kondo T, Ninomiya K, Fujii M, Kubo T, Ohashi K, Matsuoka KI, Hotta K, Tabata M, Maeda Y, Kiura K.
- Journal Title
  
  Cancer Sci.
  
  Volume: 114 Issue: 11 Pages: 4343-4354
- DOI
  10.1111/cas.15958
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19529, KAKENHI-PROJECT-23K24339
[Journal Article] CD8+ T-cell responses are boosted by dual PD-1/VEGFR2 blockade after EGFR inhibition in Egfrmutant lung cancer.2022
- Author(s)
  Nishii K, Ohashi K, Tomida S, Nakasuka T, Hirabae A,Okawa S, Nishimura J, Higo H, Watanabe H, Kano H, Ando C, Makimoto G, Ninomiya K, Kato Y, Kubo T, Ichihara E, Hotta K, Tabata M, Toyooka S, Udono H, Maeda Y, Kiura K.
- Journal Title
  
  Cancer Immunol Res.
  
  Volume: 10 Issue: 9 Pages: 1111-1126
- DOI
  10.1158/2326-6066.cir-21-0751
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K19409, KAKENHI-PROJECT-22K19529, KAKENHI-PROJECT-18H04033, KAKENHI-PROJECT-19H03667, KAKENHI-PROJECT-20H03771, KAKENHI-PROJECT-23K24339
[Journal Article] Significance of PD-L1 expression in the cytological samples of non-small cell lung cancer patients treated with immune checkpoint inhibitors2021
- Author(s)
  Hara N, Ichihara E, Harada D, Inoue K, Fujiwara K, Hosokawa S, Kishino D, Haruyuki K, Ochi N, Oda N, Hotta K, Maeda Y, Kiura K.
- Journal Title
  
  J Cancer Res Clin Oncol .
  
  Volume: 147(12) Issue: 12 Pages: 3749-3755
- DOI
  10.1007/s00432-021-03615-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03667
[Journal Article] Triple therapy with osimertinib, bevacizumab and cetuximab in EGFR-mutant lung cancer with HIF-1α/TGF-α expression2021
- Author(s)
  Nishii K, Ohashi K, Watanabe H, Makimoto G, Nakasuka T, Higo H, Ninomiya K, Kato Y, Kubo T, Rai K, Ichihara E, Hotta K, Tabata M, Maeda Y, Kiura K.
- Journal Title
  
  Mol Cancer Ther .
  
  Volume: 22(3) Issue: 9 Pages: 639-639
- DOI
  10.1158/1535-7163.mct-20-0965
- NAID
  120007185583
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03667
[Journal Article] Triple therapy with osimertinib, bevacizumab and cetuximab in EGFR-mutant lung cancer with HIF-1α/TGF-α expression2021
- Author(s)
  Nishii K, Ohashi K, Watanabe H, Makimoto G, Nakasuka T, Higo H, Ninomiya K, Kato Y, Kubo T, Rai K, Ichihara E, Hotta K, Tabata M, Maeda Y, Kiura K.
- Journal Title
  
  Oncol Lett .
  
  Volume: 22(3) Issue: 3 Pages: 639-639
- DOI
  10.3892/ol.2021.12900
- NAID
  120007185583
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08625
[Journal Article] Survival of chemo-naive patients with EGFR mutation-positive advanced non-small cell lung cancer after treatment with afatinib and bevacizumab: updates from the Okayama Lung Cancer Study Group Trial 14042021
- Author(s)
  Ninomiya T, Nogami N, Kozuki T, Harada D, Kubo T, Ohashi K, Ichihara E, Kuyama S, Kudo K, Bessho A, Sakugawa M, Fujimoto N, Aoe K, Minami D, Sugimoto K, Ochi N, Takigawa N, Hotta K, Maeda Y, Kiura K.
- Journal Title
  
  Jpn J Clin Oncol .
  
  Volume: 51(8) Issue: 8 Pages: 1269-1276
- DOI
  10.1093/jjco/hyab084
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08625, KAKENHI-PROJECT-19H03667
[Journal Article] Comparison of bronchoscopy and computed tomography-guided needle biopsy for re-biopsy in non-small cell lung cancer patients2021
- Author(s)
  Kano H, Kubo T, Ninomiya K, Ichihara E, Ohashi K, Rai K, Hotta K, Tabata M, Hiraki T, Kanazawa S, Maeda Y, Kiura K.
- Journal Title
  
  Respir Investig .
  
  Volume: 59(2) Issue: 2 Pages: 240-246
- DOI
  10.1016/j.resinv.2020.12.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08625
[Journal Article] A novel osimertinib-resistant human lung adenocarcinoma cell line harbouring mutant EGFR and activated IGF1R2021
- Author(s)
  Makimoto G, Ninomiya K, Kubo T, Sunami R, Kato Y, Ichihara E, Ohashi K, Rai K, Hotta K, Tabata M, Maeda Y, Kiura K.
- Journal Title
  
  Jpn J Clin Oncol.
  
  Volume: 51 Issue: 6 Pages: 956-965
- DOI
  10.1093/jjco/hyab048
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08625
[Journal Article] Crizotinib for recurring non-small-cell lung cancer with EML4-ALK fusion genes previously treated with alectinib: A phase II trial2021
- Author(s)
  Harada D, Isozaki H, Kozuki T, Yokoyama T, Yoshioka H, Bessho A, Hosokawa S, Takata I, Takigawa N, Hotta K, Kiura K; Okayama Lung Cancer Study Group.
- Journal Title
  
  Thorac Cancer.
  
  Volume: 12(5) Issue: 5 Pages: 643-649
- DOI
  10.1111/1759-7714.13825
- NAID
  120006955808
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03667
[Journal Article] The effects of antibiotics on the efficacy of immune checkpoint inhibitors in patients with non-small-cell lung cancer differ based on PD-L1 expression2021
- Author(s)
  Ochi N, Ichihara E, Takigawa N, Harada D, Inoue K, Shibayama T, Hosokawa S, Kishino D, Harita S, Oda N, Hara N, Hotta K, Maeda Y, Kiura K.
- Journal Title
  
  Eur J Cancer.
  
  Volume: 149 Pages: 73-81
- DOI
  10.1016/j.ejca.2021.02.040
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03667
[Journal Article] VEGFR2 blockade augments the effects of tyrosine kinase inhibitors by inhibiting angiogenesis and oncogenic signaling in oncogene-driven non-small-cell lung cancers2021
- Author(s)
  Watanabe H, Ichihara E, Kayatani H, Makimoto G, Ninomiya K, Nishii K, Higo H, Ando C, Okawa S, Nakasuka T, Kano H, Hara N, Hirabae A, Kato Y, Ninomiya T, Kubo T, Rai K, Ohashi K, Hotta K, Tabata M, Maeda Y, Kiura K.
- Journal Title
  
  Cancer Sci
  
  Volume: 112(5) Issue: 5 Pages: 1853-1864
- DOI
  10.1111/cas.14801
- NAID
  120007008532
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03667
[Journal Article] A case of dramatic reduction in cancer-associated thrombus following initiation of pembrolizumab in patient with a poor performance status and PD-L1+ lung adenocarcinoma harboring CCDC6-RET fusion gene and NF1/TP53 mutations.2021
- Author(s)
  Nakasuka T, Ohashi K, Watanabe H, Kubo T, Matsumoto S, Goto K, Hotta K, Maeda Y, Kiura K.
- Journal Title
  
  Lung Cancer.
  
  Volume: 156 Pages: 1-4
- DOI
  10.1016/j.lungcan.2021.03.022
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08625, KAKENHI-PROJECT-19H03667
[Journal Article] Key prognostic factors for EGFR-mutated non-adenocarcinoma lung cancer patients in the Japanese Joint Committee of Lung Cancer Registry Database2020
- Author(s)
  Kobayashi, K. Soejima, K. Fukunaga, K. Shintani, Y. Sekine, I. Shukuya, T. Takayama, K. Inoue, A. Okamoto, I. Kiura, K. Takahashi, K. Yamamoto, N. Takiguchi, Y. Miyaoka, E. Okumura, M. Yoshino, I.
- Journal Title
  
  Lung Cancer
  
  Volume: 146 Pages: 236-243
- DOI
  10.1016/j.lungcan.2020.06.015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08561, KAKENHI-PROJECT-17H04149, KAKENHI-PROJECT-19H03667, KAKENHI-PROJECT-19H03671
[Journal Article] Detection of epidermal growth factor receptor mutations in exhaled breath condensate using droplet digital polymerase chain reaction.2020
- Author(s)
  Nishii K, Ohashi K, Tamura T, Ninomiya K, Matsubara T, Senoo S, Kano H, Watanabe H, Oda N, Makimoto G, Higo H, Kato Y, Ninomiya T, Kubo T, Yamamoto H, Tomida S, Hotta K, Tabata M, Toyooka S, Maeda Y, Kiura K.
- Journal Title
  
  Oncol Lett
  
  Volume: 6 Issue: 6 Pages: 393-393
- DOI
  10.3892/ol.2020.12256
- NAID
  120007029912
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08625, KAKENHI-PROJECT-19H03667
[Journal Article] Impact of HER2 expression on EGFR-TKI treatment outcomes in lung tumors harboring EGFR mutations: A HER2-CS study subset analysis.2020
- Author(s)
  Ohashi K, Ninomiya K, Yoshioka H, Bessho A, Shibayama T, Aoe K, Ishikawa N, Kozuki T, Kawai H, Kuyama S, Miyoshi S, Fujitaka K, Obata H, Tsubata Y, Awaya Y, Inoue M, Inoue K, Horita N, Yanai H, Hotta K, Kiura K.
- Journal Title
  
  Lung Cancer.
  
  Volume: 150 Pages: 83-89
- DOI
  10.1016/j.lungcan.2020.09.024
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08625, KAKENHI-PROJECT-19H03667
[Journal Article] Share Beneficial effect of erlotinib and trastuzumab emtansine combination in lung tumors harboring EGFR mutations.2020
- Author(s)
  Kayatani H, Ohashi K, Ninomiya K, Makimoto G, Nishii K, Higo H, Watanabe H, Kano H, Kato Y, Ninomiya T, Kubo T, Rai K, Ichihara E, Hotta K, Tabata M, Maeda Y, Kiura K.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 532(3) Issue: 3 Pages: 341-346
- DOI
  10.1016/j.bbrc.2020.07.055
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08625, KAKENHI-PROJECT-19H03667
[Journal Article] Successful Re-administration of Osimertinib in Osimertinib-induced Interstitial Lung Disease with an Organizing Pneumonia Pattern: A Case Report and Literature Review2020
- Author(s)
  Itano J, Higo H, Ohashi K, Makimoto G, Nishii K, Hotta K, Miyahara N, Maeda Y, Kiura K.
- Journal Title
  
  Intern. Med.
  
  Volume: 59 Issue: 6 Pages: 823-828
- DOI
  10.2169/internalmedicine.3689-19
- NAID
  130007808796
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2020-03-15
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08625, KAKENHI-PROJECT-19H03667
[Journal Article] A Long-term Response to Nivolumab in a Case of PD-L1-negative Lung Adenocarcinoma with an <i>EGFR</i> Mutation and Surrounding PD-L1-positive Tumor-associated Macrophages2019
- Author(s)
  Watanabe H, Ohashi K, Nishii K, Seike K, Makimoto G, Hotta K, Maeda Y, Kiura K.
- Journal Title
  
  Intern. Med.
  
  Volume: 58 Issue: 20 Pages: 3033-3037
- DOI
  10.2169/internalmedicine.2875-19
- NAID
  130007728791
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2019-10-15
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08625
[Journal Article] Phase 2 Study of Afatinib Alone or Combined With Bevacizumab in Chemonaive Patients With Advanced Non-Small-Cell Lung Cancer Harboring EGFR Mutations: AfaBev-CS Study Protocol.2019
- Author(s)
  Ninomiya T, Ishikawa N, Inoue K, Kubo T, Yasugi M, Shibayama T, Maeda T, Fujitaka K, Kodani M, Yokoyama T, Kuyama S, Ochi N, Ueda Y, Miyoshi S, Kozuki T, Amano Y, Kubota T, Sugimoto K, Bessho A, Ishii T, Watanabe K, Oze I, Hotta K, Kiura K.
- Journal Title
  
  Clin Lung Cancer.
  
  Volume: 29 Issue: 2 Pages: 134-138
- DOI
  10.1016/j.cllc.2018.10.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04830
[Journal Article] EGFR-TKI acquired resistance in lung cancers harboring EGFR mutations in immunocompetent C57BL/6J mice.2019
- Author(s)
  Higo H, Ohashi K, Makimoto G, Nishii K, Kudo K, Kayatani H, Watanabe H, Kano H, Ninomiya K, Hotta K, Maeda Y, Kiura K.
- Journal Title
  
  Lung Cancer
  
  Volume: 136 Pages: 86-93
- DOI
  10.1016/j.lungcan.2019.08.019
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08625, KAKENHI-PROJECT-19H03667
[Journal Article] Beneficial Effect of Osimertinib Readministration in Non-small-cell Lung Cancer Harboring an Epidermal Growth Factor Receptor (<i>EGFR</i>) Mutation with a History of Acquired Resistance to Osimertinib2019
- Author(s)
  Makimoto G, Ohashi K, Senoo S, Hotta K, Maeda Y, Kiura K
- Journal Title
  
  Intern. Med.
  
  Volume: 58 Issue: 11 Pages: 1625-1627
- DOI
  10.2169/internalmedicine.2152-18
- NAID
  130007658147
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2019-06-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K19454, KAKENHI-PROJECT-19K08625
[Journal Article] Rapid Acquisition of Alectinib Resistance in ALK-Positive Lung Cancer With High Tumor Mutation Burden.2019
- Author(s)
  Makimoto G, Ohashi K, Tomida S, Nishii K, Matsubara T, Kayatani H, Higo H, Ninomiya K, Sato A, Watanabe H, Kano H, Ninomiya T, Kubo T, Rai K, Ichihara E, Hotta K, Tabata M, Toyooka S, Takata M, Maeda Y, Kiura K.
- Journal Title
  
  J Thorac Oncol.
  
  Volume: 11 Issue: 11 Pages: 2009-2018
- DOI
  10.1016/j.jtho.2019.07.017
- NAID
  120006871852
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08625, KAKENHI-PROJECT-17K10784, KAKENHI-PROJECT-18K15925
[Journal Article] Significance of re-biopsy of histological tumor samples in advanced non-small-cell lung cancer in clinical practice.2019
- Author(s)
  Hotta K, Ninomiya K, Ichihara E, Kiura K.
- Journal Title
  
  Int J Clin Oncol.
  
  Volume: 24 Issue: 1 Pages: 41-45
- DOI
  10.1007/s10147-018-1344-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04830
[Journal Article] MET or NRAS amplification is an acquired resistance mechanism to the third-generation EGFR inhibitor naquotinib2018
- Author(s)
  Ninomiya Kiichiro、Ohashi Kadoaki、Makimoto Go、Tomida Shuta、Higo Hisao、Kayatani Hiroe、Ninomiya Takashi、Kubo Toshio、Ichihara Eiki、Hotta Katsuyuki、Tabata Masahiro、Maeda Yoshinobu、Kiura Katsuyuki
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 1955-1955
- DOI
  10.1038/s41598-018-20326-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10784, KAKENHI-PROJECT-16K19454, KAKENHI-PUBLICLY-16H01574, KAKENHI-PROJECT-15H04830, KAKENHI-PROJECT-16K15458, KAKENHI-PROJECT-18K15925
[Journal Article] Combined effect of cabozantinib and gefitinib in crizotinib-resistant lung tumors harboring ROS1 fusions2018
- Author(s)
  Kato Yuka、Ninomiya Kiichiro、Ohashi Kadoaki、Tomida Shuta、Makimoto Go、Watanabe Hiromi、Kudo Kenichiro、Matsumoto Shingo、Umemura Shigeki、Goto Koichi、Ichihara Eiki、Ninomiya Takashi、Kubo Toshio、Sato Akiko、Hotta Katsuyuki、Tabata Masahiro、Toyooka Shinichi、Maeda Yoshinobu、Kiura Katsuyuki
- Journal Title
  
  Cancer Science
  
  Volume: 109 Issue: 10 Pages: 3149-3158
- DOI
  10.1111/cas.13752
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10784, KAKENHI-PROJECT-18K15925, KAKENHI-PROJECT-15H04830, KAKENHI-PROJECT-16K19454
[Journal Article] Needle wash solution cultures following EBUS-TBNA with or without endobronchial intubation.2018
- Author(s)
  Minami D, Takigawa N, Oki M, Saka H, Shibayama T, Kiura K.
- Journal Title
  
  Respir Investig.
  
  Volume: 56 Issue: 4 Pages: 356-360
- DOI
  10.1016/j.resinv.2018.03.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04830
[Journal Article] Randomized, Double-Blind Phase Ib/III Study of Erlotinib With Ramucirumab or Placebo in Previously Untreated EGFR -Mutant Metastatic Non-Small-Cell Lung Cancer (RELAY): Phase Ib Results2018
- Author(s)
  Reck Martin、Garon Edward B.、Paz-Ares Luis、Ponce Santiago、Jaime Jesus Corral、Juan Oscar、Nadal Ernest、Kiura Katsuyuki、Widau Ryan C.、He Shuang、Dalal Rita、Lee Pablo、Nakagawa Kazuhiko
- Journal Title
  
  Clinical Lung Cancer
  
  Volume: 19 Issue: 3 Pages: 213-220.e4
- DOI
  10.1016/j.cllc.2017.11.003
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04830, KAKENHI-PROJECT-16K15458
[Journal Article] Clinical significance of repeat rebiopsy in detecting the EGFR T790M secondary mutation in patients with non-small cell lung cancer2018
- Author(s)
  Ichihara Eiki、Hotta Katsuyuki、Kubo Toshio、Higashionna Tsukasa、Ninomiya Kiichiro、Ohashi Kadoaki、Tabata Masahiro、Maeda Yoshinobu、Kiura Katsuyuki
- Journal Title
  
  Oncotarget
  
  Volume: 9 Issue: 50 Pages: 29525-29531
- DOI
  10.18632/oncotarget.25705
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K15925, KAKENHI-PROJECT-15H04830
[Journal Article] Phase 3 study of ceritinib vs chemotherapy in ALK-rearranged NSCLC patients previously treated with chemotherapy and crizotinib (ASCEND-5): Japanese subset2018
- Author(s)
  Kiura Katsuyuki、Imamura Fumio、Kagamu Hiroshi、Matsumoto Shingo、Hida Toyoaki、Nakagawa Kazuhiko、Satouchi Miyako、Okamoto Isamu、Takenoyama Mitsuhiro、Fujisaka Yasuhito、Kurata Takayasu、Ito Masayuki、Tokushige Kota、Hatano Ben、Nishio Makoto
- Journal Title
  
  Japanese Journal of Clinical Oncology
  
  Volume: 48 Issue: 4 Pages: 367-375
- DOI
  10.1093/jjco/hyy016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04830, KAKENHI-PROJECT-16K15458
[Journal Article] Osimertinib Depletes EGFR T790M in the Spinal Fluid of Patients with Carcinomatous Meningitis of Lung Adenocarcinoma Harboring De Novo EGFR T790M.2018
- Author(s)
  Senoo S, Ohashi K, Nishii K, Hara N, Kano H, Ninomiya K, Maeda Y, Kiura K.
- Journal Title
  
  J Thorac Oncol.
  
  Volume: 13 Issue: 8 Pages: e140-e142
- DOI
  10.1016/j.jtho.2018.03.016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04830, KAKENHI-PROJECT-16K19454
[Journal Article] Second primary cancer in survivors of locally advanced non-small cell lung cancer treated with concurrent chemoradiation followed by surgery2018
- Author(s)
  Makimoto Go、Kubo Toshio、Oze Isao、Ohashi Kadoaki、Hotta Katsuyuki、Tabata Masahiro、Soh Junichi、Toyooka Shinichi、Katsui Kuniaki、Takigawa Nagio、Tanimoto Mitsune、Kiura Katsuyuki
- Journal Title
  
  Japanese Journal of Clinical Oncology
  
  Volume: 48 Issue: 3 Pages: 287-290
- DOI
  10.1093/jjco/hyy003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04830, KAKENHI-PROJECT-16K15458, KAKENHI-PROJECT-18K15925
[Journal Article] A phase I trial of afatinib and bevacizumab in chemo-naive patients with advanced non-small-cell lung cancer harboring EGFR mutations: Okayama Lung Cancer Study Group Trial 1404.2018
- Author(s)
  Ninomiya T, Nogami N, Kozuki T, Harada D, Kubo T, Ohashi K, Kuyama S, Kudo K, Bessho A, Fukamatsu N, Fujimoto N, Aoe K, Shibayama T, Sugimoto K, Takigawa N, Hotta K, Kiura K.
- Journal Title
  
  Lung Cancer.
  
  Volume: 115 Pages: 103-108
- DOI
  10.1016/j.lungcan.2017.11.025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K19454, KAKENHI-PROJECT-15H04830, KAKENHI-PROJECT-16K15458, KAKENHI-PROJECT-18K15925
[Journal Article] A Phase II Study of Trastuzumab Emtansine in HER2-Positive Non-Small Cell Lung Cancer2018
- Author(s)
  Hotta Katsuyuki、Aoe Keisuke、Kozuki Toshiyuki、Ohashi Kadoaki、Ninomiya Kiichiro、Ichihara Eiki、Kubo Toshio、Ninomiya Takashi、Chikamori Kenichi、Harada Daijiro、Nogami Naoyuki、Hirata Taizo、Hinotsu Shiro、Toyooka Shinichi、Kiura Katsuyuki
- Journal Title
  
  Journal of Thoracic Oncology
  
  Volume: 13 Issue: 2 Pages: 273-279
- DOI
  10.1016/j.jtho.2017.10.032
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04830, KAKENHI-PROJECT-16K15458, KAKENHI-PROJECT-18K15925
[Journal Article] Osimertinib in patients with epidermal growth factor receptor T790M advanced non-small cell lung cancer selected using cytology samples2018
- Author(s)
  Kiura Katsuyuki、Yoh Kiyotaka、Katakami Nobuyuki、Nogami Naoyuki、Kasahara Kazuo、Takahashi Toshiaki、Okamoto Isamu、Cantarini Mireille、Hodge Rachel、Uchida Hirohiko
- Journal Title
  
  Cancer Science
  
  Volume: 109 Issue: 4 Pages: 1177-1184
- DOI
  10.1111/cas.13511
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04830, KAKENHI-PROJECT-16K15458
[Journal Article] Potential influence of interleukin-6 on the therapeutic effect of gefitinib in patients with advanced non-small cell lung cancer harbouring EGFR mutations.2018
- Author(s)
  Tamura T, Kato Y, Ohashi K, Ninomiya K, Makimoto G, Gotoda H, Kubo T, Ichihara E, Tanaka T, Ichimura K, Maeda Y, Hotta K, Kiura K.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 495 Issue: 1 Pages: 360-367
- DOI
  10.1016/j.bbrc.2017.10.175
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K19454, KAKENHI-PROJECT-15H04830, KAKENHI-PROJECT-26430163, KAKENHI-PROJECT-16K15458
[Journal Article] Study Protocol: Phase-Ib Trial of Nivolumab Combined With Metformin for Refractory/Recurrent Solid Tumors.2018
- Author(s)
  Kubo T, Ninomiya T, Hotta K, Kozuki T, Toyooka S, Okada H, Fujiwara T, Udono H, Kiura K.
- Journal Title
  
  Clin Lung Cancer.
  
  Volume: 19 Issue: 6 Pages: e861-e864
- DOI
  10.1016/j.cllc.2018.07.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K19598, KAKENHI-PROJECT-18H04033, KAKENHI-PROJECT-15H04830
[Journal Article] A phase II trial of EGFR-TKI readministration with afatinib in advanced non-small-cell lung cancer harboring a sensitive non-T790M EGFR mutation: Okayama Lung Cancer Study Group trial 1403.2018
- Author(s)
  Oda N, Hotta K, Ninomiya K, Minami D, Ichihara E, Murakami T, Yokoyama T, Ichikawa H, Chikamori K, Takigawa N, Ochi N, Harita S, Maeda Y, Kiura K.
- Journal Title
  
  Cancer Chemother Pharmacol.
  
  Volume: 82 Issue: 6 Pages: 1031-1038
- DOI
  10.1007/s00280-018-3694-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04830
[Journal Article] Ceritinib in patients with advanced, crizotinib-treated, anaplastic lymphoma kinase-rearranged NSCLC: Japanese subset2017
- Author(s)
  Hida Toyoaki、Satouchi Miyako、Nakagawa Kazuhiko、Seto Takashi、Matsumoto Shingo、Kiura Katsuyuki、Nokihara Hiroshi、Murakami Haruyasu、Tokushige Kota、Hatano Ben、Nishio Makoto
- Journal Title
  
  Japanese Journal of Clinical Oncology
  
  Volume: 47 Issue: 7 Pages: 618-624
- DOI
  10.1093/jjco/hyx045
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04830, KAKENHI-PROJECT-16K15458
[Journal Article] Clinical characteristics of Japanese candidates for lung transplant for interstitial lung disease and risk factors for early death while on the waiting list2017
- Author(s)
  Higo Hisao、Kurosaki Takeshi、Ichihara Eiki、Kubo Toshio、Miyoshi Kentaroh、Otani Shinji、Sugimoto Seiichiro、Yamane Masaomi、Miyahara Nobuaki、Kiura Katsuyuki、Miyoshi Shinichiro、Oto Takahiro
- Journal Title
  
  Respiratory Investigation
  
  Volume: 55 Issue: 4 Pages: 264-269
- DOI
  10.1016/j.resinv.2017.03.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04830, KAKENHI-PROJECT-16K15458
[Journal Article] Ceritinib versus chemotherapy in patients with ALK -rearranged non-small-cell lung cancer previously given chemotherapy and crizotinib (ASCEND-5): a randomised, controlled, open-label, phase 3 trial2017
- Author(s)
  Shaw Alice T、Kim Tae Min、Crino Lucio、Gridelli Cesare、Kiura Katsuyuki、Liu Geoffrey、Novello Silvia、Bearz Alessandra、Gautschi Oliver、Mok Tony、Nishio Makoto、Scagliotti Giorgio、Spigel David R、Deudon Stephanie、Zheng Cheng、Pantano Serafino、Urban Patrick、Massacesi Cristian、et al.
- Journal Title
  
  The Lancet Oncology
  
  Volume: 18 Issue: 7 Pages: 874-886
- DOI
  10.1016/s1470-2045(17)30339-x
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04830, KAKENHI-PROJECT-16K15458
[Journal Article] Three-Year Follow-Up of an Alectinib Phase I/II Study in ALK-Positive Non-Small-Cell Lung Cancer: AF-001JP2017
- Author(s)
  Tamura Tomohide、Kiura Katsuyuki、Seto Takashi、Nakagawa Kazuhiko、Maemondo Makoto、Inoue Akira、Hida Toyoaki、Yoshioka Hiroshige、Harada Masao、Ohe Yuichiro、Nogami Naoyuki、Murakami Haruyasu、Kuriki Hiroshi、Shimada Tadashi、Tanaka Tomohiro、Takeuchi Kengo、Nishio Makoto
- Journal Title
  
  Journal of Clinical Oncology
  
  Volume: 35 Issue: 14 Pages: 1515-1521
- DOI
  10.1200/jco.2016.70.5749
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04830, KAKENHI-PROJECT-16K15458
[Journal Article] A phase II trial of carboplatin plus S-1 for elderly patients with advanced non-small-cell lung cancer with wild-type epidermal growth factor receptor: The Okayama Lung Cancer Study Group Trial 12022017
- Author(s)
  Kuyama Shoichi、Ochi Nobuaki、Bessho Akihiro、Hotta Katsuyuki、Ikeda Genyo、Kishino Daizo、Kubo Toshio、Harada Daijiro、Fujimoto Nobukazu、Nakanishi Masamoto、Umeno Takahiro、Okada Toshiaki、Chikamori Kenichi、Yamagishi Tomoko、Ohashi Kadoaki、Ichihara Eiki、Takigawa Nagio、Tanimoto Mitsune、Kiura Katsuyuki
- Journal Title
  
  Lung Cancer
  
  Volume: 112 Pages: 188-194
- DOI
  10.1016/j.lungcan.2017.08.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04830, KAKENHI-PROJECT-16K15458
[Journal Article] Triplet therapy with afatinib, cetuximab, and bevacizumab induces deep remission in lung cancer cells harboring EGFR T790M in vivo.2017
- Author(s)
  Kudo K, Ohashi K, Makimoto G, Higo H, Kato Y, Kayatani H, Kurata Y, Takami Y, Minami D, Ninomiya T, Kubo T, Ichihara E, Sato A, Hotta K, Yoshino T, Tanimoto M, Kiura K.
- Journal Title
  
  Mol Oncol
  
  Volume: Epub Issue: 6 Pages: 670-681
- DOI
  10.1002/1878-0261.12063
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H04830, KAKENHI-PROJECT-16K19454, KAKENHI-PROJECT-16K15458
[Journal Article] Study about the Efficacy of Metformin to Immune Function in Cancer Patients.2016
- Author(s)
  Watanabe M, Yamamoto H, Eikawa S, Shien K, Shien T, Soh J, Hotta K, Wada J, Hinotsu S, Fujiwara T, Kiura K, Doihara H, Miyoshi S, Udono H, Toyooka S.
- Journal Title
  
  Acta Med Okayama.
  
  Volume: 70 Pages: 327-30
- NAID
  120005828926
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04830
[Journal Article] Safety and discomfort during bronchoscopy performed under sedation with fentanyl and midazolam: a prospective study.2016
- Author(s)
  Minami D, Takigawa N, Watanabe H, Ninomiya T, Kubo T, Ohashi K, Sato A, Hotta K, Tabata M, Tanimoto M, Kiura K.
- Journal Title
  
  Jpn J Clin Oncol.
  
  Volume: 46 Issue: 9 Pages: 871-4
- DOI
  10.1093/jjco/hyw083
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K15458
[Journal Article] Synergistic effect of pacritinib with erlotinib on JAK2-mediated resistance in epidermal gowth factor receptor mutation-positive non-small cell lung Cancer.2016
- Author(s)
  Ochi N, Isozaki H, Takeyama M, Singer JW, Yamane H, Honda Y, Kiura K, Takigawa N.
- Journal Title
  
  Exp Cell Res.
  
  Volume: 344 Issue: 2 Pages: 194-200
- DOI
  10.1016/j.yexcr.2016.05.008
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04830, KAKENHI-PROJECT-16K09594
[Journal Article] Endobronchial ultrasound-guided transbronchial needle aspiration of hilar and mediastinal lymph nodes detected on 18F-fluorodeoxyglucose positron emission tomography/computed tomography2016
- Author(s)
  Minami D, Takigawa N, Oda N, Ninomiya T, Kubo T, Ohashi K, Sato A, Hotta K, Tabata M, Kaji M, Tanimoto M, Kiura K..
- Journal Title
  
  Jpn J Clin Oncol.
  
  Volume: 46 Issue: 6 Pages: 529-33
- DOI
  10.1093/jjco/hyw023
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K15458
[Journal Article] Development of a skin rash within the first week and the therapeutic effect in afatinib monotherapy for EGFR-mutant non-small cell lung cancer (NSCLC): Okayama Lung Cancer Study Group experience.2016
- Author(s)
  Kudo K, Hotta K, Bessho A, Nogami N, Kozuki T, Kuyama S, Inoue K, Harita S, Okada T, Gemba K, Fujii M, Takigawa N, Oda N, Tanimoto M, Kiura K.
- Journal Title
  
  Cancer Chemother Pharmacol.
  
  Volume: 77 Issue: 5 Pages: 1005-9
- DOI
  10.1007/s00280-015-2910-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04830, KAKENHI-PROJECT-16K15458
[Journal Article] Potential influence of being overweight on the development of hepatic dysfunction in Japanese patients with EGFR-mutated non-small cell lung cancer undergoing gefitinib monotherapy: the Okayama Lung Cancer Study Group experience.2016
- Author(s)
  Oda N, Hotta K, Yoshioka H, Kudo K, Ichihara E, Kato Y, Ninomiya K, Minami D, Ninomiya T, Kubo T, Ohashi K, Sato A, Takigawa N, Tabata M, Tanimoto M, Kiura K.
- Journal Title
  
  Cancer Chemother Pharmacol.
  
  Volume: 78 Issue: 5 Pages: 941-47
- DOI
  10.1007/s00280-016-3146-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K15458
[Journal Article] A phase II study of topotecan and cisplatin with sequential thoracic radiotherapy in elderly patients with small-cell lung cancer: Okayama Lung Cancer Study Group 0102.2016
- Author(s)
  Kubo T, Fujiwara K, Hotta K, Okada T, Kuyama S, Harita S, Ninomiya T, Kamei H, Hosokawa S, Bessho A, Maeda T, Kozuki T, Fujimoto N, Ninomiya K, Takemoto M, Kanazawa S, Takigawa N, Tabata M, Tanimoto M, Ueoka H, Kiura K.
- Journal Title
  
  Cancer Chemother Pharmacol.
  
  Volume: 78 Issue: 4 Pages: 769-74
- DOI
  10.1007/s00280-016-3135-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K15458
[Journal Article] Chemotherapy for lung cancer: still alive!2015
- Author(s)
  Katsuyuki Kiura
- Journal Title
  
  Japanese Journal of Clinical Oncology
  
  Volume: ４５ Issue: 7 Pages: 609-610
- DOI
  10.1093/jjco/hyv074
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04830
[Journal Article] Gefitinib Combined With Standard Chemoradiotherapy in EGFR-Mutant Locally Advanced Non-Small-Cell Lung Cancer: The LOGIK0902/OLCSG0905 Intergroup Study Protocol.2015
- Author(s)
  Hotta K, Sasaki J, Saeki S, Takigawa N, Katsui K, Takayama K, Nogami N, Shioyama Y, Bessho A, Kishimoto J, Tanimoto M, Kiura K, Ichinose Y.
- Journal Title
  
  Clin Lung Cancer.
  
  Volume: 17 Issue: 1 Pages: 75-79
- DOI
  10.1016/j.cllc.2015.08.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04830
[Journal Article] TAE226, a Bis-Anilino Pyrimidine Compound, Inhibits the EGFR-Mutant Kinase Including T790M Mutant to Show Anti-Tumor Effect on EGFR-Mutant Non-Small Cell Lung Cancer Cells2015
- Author(s)
  Otani H, Yamamoto H, Takaoka M, Sakaguchi M, Soh J, Jida M, Ueno T, Kubo T, Asano H, Tsukuda K, Kiura K, Hatakeyama S, Kawahara E, Naomoto Y, Miyoshi S, Toyooka S
- Journal Title
  
  PLoS One
  
  Volume: 10 Issue: 6 Pages: e0129838-e0129838
- DOI
  10.1371/journal.pone.0129838
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14382, KAKENHI-PROJECT-15H04830, KAKENHI-PROJECT-25293302, KAKENHI-PROJECT-26290039
[Journal Article] Endobronchial ultrasound-guided transbronchial biopsy with or without a guide sheath for diagnosis of lung Cancer.2015
- Author(s)
  Minami D, Takigawa N, Morichika D, Kubo T, Ohashi K, Sato A, Hotta K, Tabata M, Tanimoto M, Kiura K.
- Journal Title
  
  Respir Investig.
  
  Volume: 53 Issue: 3 Pages: 93-97
- DOI
  10.1016/j.resinv.2014.10.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24659404
[Journal Article] Impact of body surface area on survival in EGFR-mutant non-small cell lung cancer patients treated with gefitinib monotherapy: observational study of the Okayama Lung Cancer Study Group 0703.2015
- Author(s)
  Kudo K, Hotta K, Ichihara E, Yoshioka H, Kunimasa K, Tsubouchi K, Iwasaku M, Kato Y, Oze I, Takigawa N, Tanimoto M, Kiura K.
- Journal Title
  
  Cancer Chemother Pharmacol.
  
  Volume: 76 Issue: 2 Pages: 251-256
- DOI
  10.1007/s00280-015-2789-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04830
[Journal Article] Afatinib versus cisplatin plus pemetrexed in Japanese patients with advanced non-small cell lung cancer harboring activating EGFR mutations: Subgroup analysis of LUX-Lung 3.2015
- Author(s)
  Kato T, Yoshioka H, Okamoto I, Yokoyama A, Hida T, Seto T, Kiura K, Massey D, Seki Y, Yamamoto N.
- Journal Title
  
  Cancer Sci.
  
  Volume: 106 Issue: 9 Pages: 1202-1211
- DOI
  10.1111/cas.12723
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04830
[Journal Article] The Role of STAT3 in Non-Small Cell Lung Cancer.2014
- Author(s)
  Harada D, Takigawa N, Kiura K.
- Journal Title
  
  Cancers
  
  Volume: 26 Issue: 2 Pages: 708-722
- DOI
  10.3390/cancers6020708
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24591182
[Journal Article] Src mediates ERK reactivation in gefitinib resistance in non-small cell lung cancer.2014
- Author(s)
  Ochi N, Takigawa N, Harada D, Yasugi M, Ichihara E, Hotta K, Tabata M, Tanimoto M, Kiura K.
- Journal Title
  
  Exp Cell Res.
  
  Volume: 322 Issue: 1 Pages: 168-177
- DOI
  10.1016/j.yexcr.2014.01.007
- NAID
  120005517858
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390221, KAKENHI-PROJECT-24591182, KAKENHI-PROJECT-25670399
[Journal Article] Vaccination With NY-ESO-1 Overlapping Peptides Mixed With Picibanil OK-432 and Montanide ISA-51 in Patients With Cancers Expressing the NY-ESO-1 Antigen2014
- Author(s)
  Wada H, Isobe M, Kakimi K, Mizote Y, Eikawa S, Sato E, Takigawa N, Kiura K, Tsuji K, Iwatsuki K, Yamasaki M, Miyata H, Matsushita H, Udono H, Seto Y, Yamada K, Nishikawa H, Pan L, Venhaus R, Oka M, Doki Y, Nakayama E.
- Journal Title
  
  J Immunother
  
  Volume: 37(2) Issue: 2 Pages: 84-92
- DOI
  10.1097/cji.0000000000000017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300354, KAKENHI-PROJECT-23591169, KAKENHI-PROJECT-24501329, KAKENHI-PROJECT-25430148, KAKENHI-PROJECT-25430161, KAKENHI-PROJECT-25462014, KAKENHI-PROJECT-25670399, KAKENHI-PROJECT-26290054, KAKENHI-PROJECT-26670581
[Journal Article] The Role of STAT3 in Non-Small Cell Lung Cancer.2014
- Author(s)
  Harada D, Takigawa N, Kiura K.
- Journal Title
  
  Cancers (Basel)
  
  Volume: 6 Pages: 708-722
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-23390221
[Journal Article] Everolimus prolonged survival in transgenic mice with EGFR-driven lung tumors.2014
- Author(s)
  Yasugi M, Takigawa N, Ochi N, Ohashi K, Harada D, Ninomiya T, Murakami T, Honda Y, Ichihara E, Tanimoto M, Kiura K.
- Journal Title
  
  Exp Cell Res.
  
  Volume: 326 Issue: 2 Pages: 201-209
- DOI
  10.1016/j.yexcr.2014.04.012
- NAID
  120005526613
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-23390221, KAKENHI-PROJECT-24591182, KAKENHI-PROJECT-25670399
[Journal Article] Factor associated with failure to administer subsequent treatment after progression in the first-line chemotherapy in EGFR-mutant non-small cell lung cancer: Okayama Lung Cancer Study Group experience.2014
- Author(s)
  Kato Y, Hotta K, Takigawa N, Nogami N, Kozuki T, Sato A, Ichihara E, Kudo K, Oze I, Tabata M, Shinkai T, Tanimoto M, Kiura K.
- Journal Title
  
  Cancer Chemother Pharmacol.
  
  Volume: 73 Issue: 5 Pages: 943-950
- DOI
  10.1007/s00280-014-2425-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24659404
[Journal Article] Effect of AZD1480 in an epidermal growth factor receptor-driven lung cancer model2014
- Author(s)
  Murakami Toshi, Takigawa Nagio, Ninomiya Takashi, Ochi Nobuaki, Yasugi Masaaki, Honda Yoshihiro, Kubo Toshio, Ichihara Eiki, Hotta Katsuyuki, Tanimoto Mitsune, Kiura Katsuyuki
- Journal Title
  
  Lung Cancer
  
  Volume: 83 Issue: 1 Pages: 30-36
- DOI
  10.1016/j.lungcan.2013.10.011
- NAID
  120005473065
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591182, KAKENHI-PROJECT-25670399
[Journal Article] A new human lung adenocarcinoma cell line harboring the EML4-ALK fusion gene.2014
- Author(s)
  Isozaki H, Yasugi M, Takigawa N, Hotta K, Ichihara E, Taniguchi A, Toyooka S, Hashida S, Sendo T, Tanimoto M, Kiura K.
- Journal Title
  
  Jpn J Clin Oncol
  
  Volume: 2014 Issue: 10 Pages: 963-968
- DOI
  10.1093/jjco/hyu110
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-23390221
[Journal Article] Novel germline mutation in the transmembrane domain of HER2 in familial lung adenocarcinomas.2014
- Author(s)
  Yamamoto H, Higasa K, Sakaguchi M, Shien K, Soh J, Ichimura K, Furukawa M, Hashida S, Tsukuda K, Takigawa N, Matsuo K, Kiura K, Miyoshi S, Matsuda F, Toyooka S.
- Journal Title
  
  J Natl Cancer Inst
  
  Volume: 106 Issue: 1
- DOI
  10.1093/jnci/djt338
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390221, KAKENHI-PROJECT-25670399, KAKENHI-PROJECT-26290039
[Journal Article] Afatinib prolongs survival compared with gefitinib in an epidermal growth factor receptor-driven lung cancer model.2013
- Author(s)
  Ninomiya T, Takigawa N, Ichihara E, Ochi N, Murakami T, Honda Y, Kubo T, Minami D, Kudo K, Tanimoto M, Kiura K.
- Journal Title
  
  Mol Cancer Ther.
  
  Volume: 12 Issue: 5 Pages: 589-597
- DOI
  10.1158/1535-7163.mct-12-0885
- NAID
  120005359109
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390221, KAKENHI-PROJECT-24591182, KAKENHI-PROJECT-25670399
[Journal Article] Subpopulation of small-cell lung cancer cells expressing CD133 and CD87 show resistance to chemotherapy.2013
- Author(s)
  Kubo T, Takigawa N, Osawa M, Harada D, Ninomiya T, Ochi N, Ichihara E, Yamane H, Tanimoto M, Kiura K.
- Journal Title
  
  Cancer Sci.
  
  Volume: 104 Issue: 1 Pages: 78-84
- DOI
  10.1111/cas.12045
- NAID
  120005311967
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390221
[Journal Article] Lower gefitinib dose led to earlier resistance acquisition before emergence of T790M mutation in epidermal growth factor receptor-mutated lung cancer model.2013
- Author(s)
  Hayakawa H, Ichihara E, Ohashi K, Ninomiya T, Yasugi M, Takata S, Sakai K, Matsumoto K, Takigawa N, Tanimoto M, Kiura K.
- Journal Title
  
  Cancer Sci.
  
  Volume: 104 Issue: 11 Pages: 1440-1446
- DOI
  10.1111/cas.12284
- NAID
  120005468272
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390221, KAKENHI-PROJECT-24300329
[Journal Article] 抗PD-1抗体2013
- Author(s)
  近藤英生, 木浦勝行
- Journal Title
  
  呼吸
  
  Volume: 32 Pages: 1141-1147
- Data Source
  KAKENHI-PROJECT-25670399
[Journal Article] Vandetanib is effective in EGFR-mutant lung cancer cells with PTEN deficiency.2013
- Author(s)
  Takeda H, Takigawa N, Ohashi K, Minami D, Kataoka I, Ichihara E, Ochi N, Tanimoto M, Kiura K.
- Journal Title
  
  Exp Cell Res
  
  Volume: 319 Issue: 4 Pages: 417-427
- DOI
  10.1016/j.yexcr.2012.12.018
- NAID
  120005359097
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390221, KAKENHI-PROJECT-24591182, KAKENHI-PROJECT-25670399
[Journal Article] Acquired resistance to EGFR inhibitors is associated with a manifestation of stem cell-like properties in cancer cells.2013
- Author(s)
  Shien K, Toyooka S, Yamamoto H, Soh J, Jida M, Thu KL, Hashida S, Maki Y, Ichihara E, Asano H, Tsukuda K, Takigawa N, Kiura K, Gazdar AF, Lam WL, Miyoshi S.
- Journal Title
  
  Cancer Res.
  
  Volume: 73 Issue: 10 Pages: 3051-3061
- DOI
  10.1158/0008-5472.can-12-4136
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390221, KAKENHI-PROJECT-23592061
[Journal Article] Vandetanib is effective in EGFR-mutant lung cancer cells with PTEN deficiency.2013
- Author(s)
  Takeda H, Takigawa N, Ohashi K, Minami D, Kataoka I, Ichihara E, Ochi N, Tanimoto M, Kiura K.
- Journal Title
  
  Mol Cancer Res
  
  Volume: 319 Issue: 2 Pages: 417-423
- DOI
  10.1158/1541-7786.mcr-12-0401
- NAID
  120005359097
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390221, KAKENHI-PROJECT-23651046, KAKENHI-PROJECT-24310042, KAKENHI-PLANNED-23114010
[Journal Article] Impact of physical size on gefitinib efficacy in patients with non-small cell lung cancer harboring EGFR mutations.2013
- Author(s)
  Ichihara E, Hotta K, Takigawa N, Kudo K, Kato Y, Honda Y, Hayakawa H, Minami D, Sato A, Tabata M, Tanimoto M, Kiura K.
- Journal Title
  
  Lung Cancer.
  
  Volume: 81 Issue: 3 Pages: 435-439
- DOI
  10.1016/j.lungcan.2013.05.021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390221
[Journal Article] Antitumor Impact of p14ARF on Gefitinib-Resistant Non-Small Cell Lung Cancers.2013
- Author(s)
  Saito K, Takigawa N, Ohtani N, Iioka H, Tomita Y, Ueda R, Fukuoka J, Kuwahara K, Ichihara E, Kiura K, Kondo E.
- Journal Title
  
  Molecule Cancer Therapeutics
  
  Volume: 12 Issue: 8 Pages: 1616-1628
- DOI
  10.1158/1535-7163.mct-12-1239
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300343, KAKENHI-PROJECT-23390221, KAKENHI-PROJECT-24590388, KAKENHI-PUBLICLY-25112716, KAKENHI-PROJECT-25290062, KAKENHI-PROJECT-25670263
[Journal Article] Selective cyclooxygenase-2 inhibitor prevents cisplatin-induced tumorigenesis in A/J mice.2012
- Author(s)
  Okada T, Takigawa N, Kishino D, Katayama H, Kuyama S, Sato K, Mimoto J, Ueoka H, Tanimoto M, Kiura K.
- Journal Title
  
  Acta Med Okayama.
  
  Volume: 66 Pages: 1795-1802
- NAID
  120004247096
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390221
[Journal Article] STAT3 expression in activating EGFR-driven adenocarcinoma of the lung2012
- Author(s)
  Takata Saburo, Takigawa Nagio, Segawa Yoshihiko, Kubo Toshio, Ohashi Kadoaki, Kozuki Toshiyuki, Teramoto Norihiro, Yamashita Motohiro, Toyooka Shinichi, Tanimoto Mitsune, Kiura Katsuyuki
- Journal Title
  
  Lung Cancer
  
  Volume: 75 Issue: 1 Pages: 24-29
- DOI
  10.1016/j.lungcan.2011.05.015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590995, KAKENHI-PROJECT-23390221
[Journal Article] Aberrant DNA methylation profile in pleural fluid for differential diagnosis of malignant pleural mesothelioma.2012
- Author(s)
  Fujii M, Fujimoto N, Hiraki A, Gemba K, Aoe K, Umemura S, Katayama H, Takigawa N, Kiura K, Tanimoto M, Kishimoto T..
- Journal Title
  
  Cancer Sci
  
  Volume: 103 Issue: 3 Pages: 510-4
- DOI
  10.1111/j.1349-7006.2011.02180.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659432
[Journal Article] Lung cancers with acquired resistance to EGFR inhibitors occasionally harbor BRAF gene mutations but lack mutations in KRAS, NRAS, or MEK1.2012
- Author(s)
  Ohashi K, Sequist LV, Shien K, Aoe K, Toyooka S, Kiura K, Kris MG, Engelman JA, Vnencak-Jones CL, Dias-Santagata D, Ladanyi M, Pao W. et al
- Journal Title
  
  Proc Natl Acad Sci U S A.
  
  Volume: 109 Issue: 31
- DOI
  10.1073/pnas.1203530109
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390221
[Journal Article] Aberrant DNA methylation profile in pleural fluid for differential diagnosis of malignant pleural mesothelioma.2012
- Author(s)
  Fujii M, Fujimoto N, Hiraki A, Gemba K, Aoe K, Umemura S, Katayama H, Takigawa N, Kiura K, Tanimoto M, Kishimoto T.
- Journal Title
  
  Cancer Sci.
  
  Volume: 103 Pages: 510-514
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659432
[Journal Article] Strong anti-tumor effect of NVP-AUY922, a novel Hsp90 inhibitor, on non-small cell lung cancer2012
- Author(s)
  Ueno T, Tsukuda K, Toyooka S, Ando M, Takaoka M, Soh J, Asano H, Maki Y, Muraoka T, Tanaka N, Shien K, Furukawa M, Yamatsuji T, Kiura K, Naomoto Y, Miyoshi S.
- Journal Title
  
  Lung Cancer
  
  Volume: 76 Issue: 1 Pages: 26-31
- DOI
  10.1016/j.lungcan.2011.09.011
- NAID
  120005311966
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659432
[Journal Article] JAK2-related pathway induces acquired erlotinib resistance in lung cancer cells harboring an epidermal growth factor receptor-activating mutation2012
- Author(s)
  Harada D, Takigawa N, Ochi N, Ninomiya T, Yasugi M, Kubo T, Takeda H, Ichihara E, Ohashi K, Takata S, Tanimoto M, Kiura K
- Journal Title
  
  Cancer Sci
  
  Volume: 103 Issue: 10 Pages: 1795-1802
- DOI
  10.1111/j.1349-7006.2012.02363.x
- NAID
  120005311974
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390221, KAKENHI-PROJECT-24591182
[Journal Article] Liposomal delivery of microRNA-7-expressing plasmid overcomes epidermal growth factor receptor tyrosine kinase inhibitor-resistance in lung cancer cells2011
- Author(s)
  Rai K, Takigawa N, Ito S, Kashihara H, Ichihara E, Yasuda T, Shimizu K, Tanimoto M, Kiura K
- Journal Title
  
  Mol Cancer Ther
  
  Volume: 10 Pages: 1720-1727
- NAID
  130004903196
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390221
[Journal Article] Liposomal delivery of MicroRNA-7-expressing plasmid overcomes epidermal growth factor receptor tyrosine kinase inhibitor-resistance in lung cancer cells2011
- Author(s)
  Kammei Rai, Takigawa Nagio, Ito Sachio, Kashihara Hiromi, Ichihara Eiki, Yasuda Tatsuji, Shimizu Kenji, Tanimoto Mitsune, Kiura Katsuyuki
- Journal Title
  
  Molecular Cancer Therapeutics
  
  Volume: 10 Issue: 9 Pages: 1720-1727
- DOI
  10.1158/1535-7163.mct-11-0220
- NAID
  120005232489
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590995
[Journal Article] Is adenosine deaminase in pleural fluid a useful marker for differentiating tuberculosis from lung cancer or mesothelioma in Japan, a country with intermediate incidence of tuberculosis?2011
- Author(s)
  Ogata Y, Aoe K, Hiraki A, Murakami K, Kishino D, Chikamori K, Maeda T, Ueoka H, Kiura K, Tanimoto M.
- Journal Title
  
  Acta Med Okayama
  
  Volume: 65 Pages: 259-63
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659432
[Journal Article] Establishment of pemetrexed-resistant non-small cell lung cancer cell lines2011
- Author(s)
  Zhang D, Ochi N, Takigawa N, Tanimoto I, Ichihara E, Hotta K, Tabata M, Tanimoto M, Kiura K
- Journal Title
  
  Cancer Lett
  
  Volume: 309 Issue: 2 Pages: 228-235
- DOI
  10.1016/j.canlet.2011.06.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390221
[Journal Article] Medical treatment of mesothelioma: anything new?2011
- Author(s)
  Takigawa N, Kiura K, Kishimoto T
- Journal Title
  
  Curr Oncol Rep
  
  Volume: 13 Issue: 4 Pages: 265-71
- DOI
  10.1007/s11912-011-0172-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659432
[Journal Article] Phase III trial comparing docetaxel and cisplatin combination chemotherapy with mitomycin, vindesine, and cisplatin combination chemotherapy with concurrent thoracic radiotherapy in locally advanced non-small-cell lung cancer : OLCSG 00072010
- Author(s)
  Segawa Y, Kiura K, Takigawa N, et al.
- Journal Title
  
  J Clin Oncol.
  
  Volume: 28 Pages: 3299-3306
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659209
[Journal Article] Early palliative care in non-small-cell lung cancer.2010
- Author(s)
  Ichihara E, Matsuoka J, Kiura K.
- Journal Title
  
  N Engl J Med
  
  Volume: 363 Pages: 2263-2263
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659209
[Journal Article] Effects of vandetanib on lung adenocarcinoma cells emerging an acquired EGFR T790M mutation in vivo. Cancer Res. 69(12) : 5091-8, 20092009
- Author(s)
  Ichihara E, Ohashi K, Takigawa N, Osawa M, Ogino A, Tanimoto M, Kiura K
- Journal Title
  
  Cancer Res 69
  
  Pages: 5091-5098
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659209
[Journal Article] Effect of gefitinib on N-nitrosamine-4-(methylnitrosamino)-1 -(3-pyridyl)-1-butanone induced lung tumorigenesis in A/J mice2009
- Author(s)
  Kishino D, Kiura K, Takigawa N, Katayama H, Kuyama S, Sato K, Okada T, Ohashi K, Tanimoto M
- Journal Title
  
  Lung Cancer (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590895
[Journal Article]2009
- Author(s)
  木浦勝行瀧川奈義夫
- Journal Title
  
  がん化学療法・分子標的治療update(中外医学社)
  
  Pages: 317-323
- Data Source
  KAKENHI-PROJECT-21659209
[Journal Article] Effects of vandetanib on lung adenocarcinoma cells harboring epidermal growth factor receptor T790M mutation in vivo.2009
- Author(s)
  Ichihara E, Ohashi K, Takigawa N, Osawa M, Ogino A, Tanimoto M, Kiura K.
- Journal Title
  
  Cancer Research 69
  
  Pages: 5091-5098
- NAID
  130004505698
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590995
[Journal Article] Chemopreventive effects of gefitinib on nonsmoking-related lung tumorigenesis in activating epidermal growth factor receptor transgenic mice.2009
- Author(s)
  Ohashi K, Takigawa N, Osawa M, Ichihara E, Takeda H, Kubo T, Hirano S, Yoshino T, Takata M, Tanimoto M, Kiura K
- Journal Title
  
  Cancer Res 69
  
  Pages: 7088-7095
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659209
[Journal Article] Comprehensive analysis of EGFR signaling pathways in Japanese patients with non-small cell lung cancer2009
- Author(s)
  Hosokawa S, Toyooka S, Fujiwara Y, Tokumo M, Soh J, Takigawa N, Hotta K, Yoshino T, Date H, Tanimoto M, Kiura K
- Journal Title
  
  Lung Cancer (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590895
[Journal Article] Comprehensive analysis of EGFR signaling pathways in Japanese patients with non-small cell lung cancer.2009
- Author(s)
  Hosokawa S, Toyooka S, Fujiwara Y, Tokumo M, Soh J, Takigawa N, Hotta K, Yoshino T, Date H, Tanimoto M, Kiura K.
- Journal Title
  
  Lung Cancer 66
  
  Pages: 107-113
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590995
[Journal Article] Effect of gefitinib on N-nitrosamine-4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone induced lung tumorigenesis in A/J mice2009
- Author(s)
  Kishino D, Kiura K, Takigawa N., et al
- Journal Title
  
  Lung Cancer (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590895
[Journal Article] Chemopreventive effects of gefitinib on nonsmoking-related lung tumorigenesis in activating epidermal growth factor receptor transgenic mice.2009
- Author(s)
  Ohashi K, Takigawa N, Osawa M, Ichihara E, Takeda H, Kubo T, Hirano S, Yoshino T, Takata M, Tanimoto M, Kiura K.
- Journal Title
  
  Cancer Research 69
  
  Pages: 7088-7095
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590995
[Journal Article] GGOを呈する病変の分子生物学的検討2009
- Author(s)
  瀧川奈義夫, 木浦勝行
- Journal Title
  
  日本胸部臨床 68
  
  Pages: 131-138
- Data Source
  KAKENHI-PROJECT-18590851
[Journal Article] Effects of vandetanib on lung adenocarcinoma cells emerging an acquired EGFR T790M mutation2009
- Author(s)
  Ichihara E, Ohashi K, Takigawa N, Osawa M, Ogino A, Tanimoto M, Kiura K
- Journal Title
  
  in vivo Cancer Res (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590895
[Journal Article] Effect of gefitinib on N-nitrosamine-4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone induced lung tumorigenesis in A/J mice.2009
- Author(s)
  Kishino D, Kiura K, Takigawa N, Katayama H, Kuyama S, Sato K, Okada T, Ohashi K, Tanimoto M
- Journal Title
  
  Lung Cancer 65
  
  Pages: 284-289
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659209
[Journal Article] Impact of HER2 gene and protein status on the treatment outcome of cisplatin-based chemoradiotherapy for locally advanced non-small cell lung cancer2008
- Author(s)
  Kuyama s, Hotta K, Tabata M, Segawa Y, Fujiwara Y. Takigawa N. Kiura K, Deoka H, Eguchi K. Taniioto M.
- Journal Title
  
  J Thorac Oncol 3
  
  Pages: 477-482
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590851
[Journal Article] Induction of lung adenocarcinoma in transgenic mice expressing activated EGFR driven by the SP-C promoter.2008
- Author(s)
  Ohashi K, Rai K, Kiura K., et al
- Journal Title
  
  Cancer Sci1747-53 99
  
  Pages: 1747-1753
- NAID
  10024010760
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590895
[Journal Article] Induction of lung adenocarcinoma in transgenic mice expressing activated EGFR driven by the SP-C promoter2008
- Author(s)
  Ohashi K, Rai K, Fujiwara Y, Osawa M, Hirano S, Takata K, Kondo E, Yoshino T, Takata M, Tanimoto M, Kiura K
- Journal Title
  
  99
  
  Pages: 1747-1753
- NAID
  10024010760
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590895
[Journal Article] Aberrant promoter hypermethylation in serum DNA from patients with silicosis2008
- Author(s)
  梅村茂樹、藤本伸一、平木章夫、玄馬顕一、瀧川奈義夫、藤原慶一、藤井昌学、梅村啓史、佐藤守、田端雅弘、上岡博、木浦勝行、岸本卓巳、谷本光音
- Journal Title
  
  Carcinogenesis 第29巻
  
  Pages: 1845-1849
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590852
[Journal Article] Triple combination chemotherapy with cisplatin, docetaxel and irinotecan for advanced non-small-cell lung cancer : A phase I/II trial2007
- Author(s)
  Kiura K, Takigawa N, Segawa Y, Tabata M, Shibayama T, Gemba K, Bessho A, Fujimoto N, Takata I, Hotta K, Fujiwara K, Tokuda Y, Kuyama S, Shinkai T, Hiroshi Ueoka H, Tanimoto M
- Journal Title
  
  JThor Oncol 2(1)
  
  Pages: 44-50
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590746
[Journal Article] Triple combination chemotherapy with cisplatin, docetaxel and irinotecan for advanced non-small-cell lung cancer : A phase I/II trial2007
- Author(s)
  Kiura K, Takigawa N, Segawa Y, et al.
- Journal Title
  
  J Thor Oncol 2・1
  
  Pages: 44-50
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590746
[Journal Article] Activation of downstream epidermal growth factor receptor(EGFR)signaling provides gefitinib-resistance in cells carrying EGFR mutation2007
- Author(s)
  Uchida A, Hirano S, Kitao H, Ogino A, Rai K, Toyooka S, Takigawa N, Tabata M, Takata M, Kiura K, Tanimoto M
- Journal Title
  
  Cancer Sci 98
  
  Pages: 357-363
- NAID
  10019481589
- Data Source
  KAKENHI-PROJECT-18590851
[Journal Article] Point mutation of K-ras gene in cisplatin-induced lung tumours in A/J mice. Lung Cancer.2007
- Author(s)
  Hisamoto A, Kondo E, Kiura K, Okada T, Hosokawa S, Mimoto J, Takigawa N, Tabata M, Tanimoto M:
- Journal Title
  
  Lung Cancer 58
  
  Pages: 15-20
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590895
[Journal Article] Emergence of epidermal growth factor receptor T790M mutation during chronic exposure to gefitinib in a non small cell lung cancer cell line.2007
- Author(s)
  Ogino A, Kitao H, Hirano S, Uchida A, Ishiai M, Kozuki T, Takigawa N, Takata M, Kiura K, Tanimoto M
- Journal Title
  
  Cancer Res. 67
  
  Pages: 7807-7814
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590895
[Journal Article] Point mutation of K-ras gene in cisplatin-induced lung tumours in A/J mice.2007
- Author(s)
  Hisamoto A, Kondo E, Kiura K, Okada T, Hosokawa S, Mimoto J, Takigawa N, et. al.
- Journal Title
  
  Lung Cancer 58
  
  Pages: 15-20
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590851
[Journal Article] Activation of downstream epidermal growth factor receptor (EGFR) signaling provides gefitinib-resistance in cells carrying EGFR mutation.2007
- Author(s)
  Uchida A, Hirano S, Kitao H, Ogino A, Rai K, Toyooka S, Takigawa N, Tabata M, Takata M, Kiura K. Tanimoto M.
- Journal Title
  
  Cancer Sci. 98(3)
  
  Pages: 357-63
- NAID
  10019481589
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590746
[Journal Article] Activation of downstream epidermal growth factor receptor (EGFR) signaling provides gefitinib-resistance in cells carrying EGFR mutation2007
- Author(s)
  Uchida A, Hirano S, Kitao H, Rai K, Toyooka S, Takigawa N, Tabata M, Takata M, Kiura K, Tanimoto M
- Journal Title
  
  Cancer Sci. 98・3
  
  Pages: 357-363
- NAID
  10019481589
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590746
[Journal Article] Mutation of the epidermal growth factor receptor gene in the development of adenocarcinoma of the lung2007
- Author(s)
  Kozuki T, Hisamoto A, Tabata M, Takigawa N, Kiura K, Segawa Y, Nakata M, Mandai K, Eguchi K, Ueoka H, Tanimoto M.
- Journal Title
  
  Lung Cancer 58
  
  Pages: 30-35
- Data Source
  KAKENHI-PROJECT-18590851
[Journal Article] Activation of downstream epidermal growth factor receptor (EGFR) signaling provides gefitinib-resistance in cells carrying EGFR mutation2007
- Author(s)
  Uchida A, Hirano S, Kitao H, Ogino A, Rai K, Toyooka S, Takigawa N, Tabata M, Takata M, Kiura K, Tanimoto M
- Journal Title
  
  Cancer Sci. 98
  
  Pages: 357-363
- NAID
  10019481589
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590895
[Journal Article] Emergence of epidermal growth factor receptor T790M mutation during chronic exposure to gefitinib in a non small cell lung cancer cell line2007
- Author(s)
  Ogino A, Kitao H, Hirano S, Uchida A, Ishiai M, Kozuki T, Takigawa N, Takata M, Kiura K, Tanimoto M
- Journal Title
  
  Cancer Res 67
  
  Pages: 7807-7814
- Data Source
  KAKENHI-PROJECT-18590851
[Journal Article] Point mutation of K-ras gene in cisplatin-induced lung tumours in A/J mice2007
- Author(s)
  Hisamoto A, Kondo E, Kiura K, Okada T, Hosokawa S, Mimoto J, Takigawa N, Tanimoto M
- Journal Title
  
  Lung Cancer 58
  
  Pages: 15-20
- Data Source
  KAKENHI-PROJECT-18590851
[Journal Article] Activation of downstream epidermal growth factor receptor (EGFR) signaling provides gefitinib-resistance in cells carrying EGFR mutation2007
- Author(s)
  Uchida A, Hirano S, Kitao H, Ogino A, Rai K, Toyooka S, Takigawa N, Tabata M, Takata M, Kiura K, Tanimoto M.
- Journal Title
  
  Cancer Sci. 98・3
  
  Pages: 357-363
- NAID
  10019481589
- Data Source
  KAKENHI-PROJECT-16590746
[Journal Article] Second primary cancer in survivors following concurrent chemoradiation for locally advanced non-small-cell lung cancer.2006
- Author(s)
  Takigawa N, Kiura K, Segawa Y, Watanabe Y, Kamei H, Moritaka T, Shibayama T, Ueoka H, Gemba K, Yonei T, Tabata M, Shinkai T, Hiraki S, Takemoto M, Kanazawa S, Matsuo K, Tanimoto M.
- Journal Title
  
  BrJ Cancer 95(9)
  
  Pages: 1142-4
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590746
[Journal Article] Second primary cancer in survivors following concurrent chemoradiation for locally advanced non-small-cell lung cancer.2006
- Author(s)
  Takigawa N, Kiura K, Segawa Y et al.
- Journal Title
  
  Br J Cancer 95・9
  
  Pages: 1142-1144
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590746
[Journal Article] The relationship between epidermal growth factor receptor mutations and clinicopathologic features in non-small cell lung cancers.2005
- Author(s)
  Tokumo M, Toyooka S, Kiura K, et al.
- Journal Title
  
  Clin Cancer Res 11・3
  
  Pages: 1167-1173
- Data Source
  KAKENHI-PROJECT-16590746
[Journal Article] Determinants of cisplatin and irinotecan activities in human lung adenocarcinoma cells : evidence of cisplatin accumulation and topoisomerase I activity2005
- Author(s)
  Matsumura T, Takigawa N, Kiura K, et al.
- Journal Title
  
  In Vivo. 19・4
  
  Pages: 717-721
- Data Source
  KAKENHI-PROJECT-16590746
[Journal Article] EGFR mutation and response of lung cancer to gefitinib.2005
- Author(s)
  Toyooka S, Kiura K, Mitsudomi T
- Journal Title
  
  N Engl J Med. 352・20
  
  Pages: 2136-2136
- Data Source
  KAKENHI-PROJECT-16590746
[Journal Article] Complexity in the treatment of pulmonary large cell neuroendocrine carcinoma.2005
- Author(s)
  Kozuki T, Fujimoto N, Ueoka H, Kiura K, et al.
- Journal Title
  
  J Cancer Res Clin Oncol 131・3
  
  Pages: 147-151
- Data Source
  KAKENHI-PROJECT-16590746
[Journal Article] Interstitial lung disease in Japanese patients with non-small cell lung cancer receiving gefitinib : an analysis of risk factors and treatment outcomes in Okayama Lung Cancer Study Group.2005
- Author(s)
  Hotta K, Kiura K, et al.
- Journal Title
  
  Cancer J 11・5
  
  Pages: 417-424
- Data Source
  KAKENHI-PROJECT-16590746
[Journal Article] Can dose-dense chemotherapy improve outcome in patients with better prognosis small-cell lung cancer?2005
- Author(s)
  Kiura K, Saijo N
- Journal Title
  
  Nat Clinic Pract Oncol 2・12
  
  Pages: 610-611
- Data Source
  KAKENHI-PROJECT-16590746
[Journal Article] Induction chemotherapy, surgical resection, and high-dose chemotherapy for mediastinal nonseminomatous germ-cell tumor. 20052005
- Author(s)
  Date H, Kiura K, et al.
- Journal Title
  
  Thorac Cardiovasc Surg.J 30・4
  
  Pages: 1205-1206
- Data Source
  KAKENHI-PROJECT-16590746
[Journal Article] Cisplatin down-regulates topoisomerase I activity in lung cancer cell lines2004
- Author(s)
  Aoe K, Kiura K, Ueoka H, et al.
- Journal Title
  
  Anticancer Res 24・6
  
  Pages: 3893-3897
- Data Source
  KAKENHI-PROJECT-16590746
[Journal Article] Effect of gefitinib ('Iressa', ZD1839) on brain metastases in patients with advanced non-small-cell lung cancer.2004
- Author(s)
  Hotta K, Kiura K, Ueoka H, et al.
- Journal Title
  
  Lung Cancer 46・2
  
  Pages: 255-261
- Data Source
  KAKENHI-PROJECT-16590746
[Journal Article] Preoperative concurrent chemoradiotherapy with cisplatin and docetaxel in patients with locally advanced non-small-cell lung cancer.2004
- Author(s)
  Katayama H, Ueoka H, Kiura K, et al.
- Journal Title
  
  Br J Cancer 90・5
  
  Pages: 979-984
- Data Source
  KAKENHI-PROJECT-16590746
[Journal Article] Long-term effect of gefitinib (ZD1839) on squamous cell carcinoma of the lung.2004
- Author(s)
  Kozuki T, Kiura K, Ueoka H, et al.
- Journal Title
  
  Anticancer Res 24・1
  
  Pages: 393-396
- Data Source
  KAKENHI-PROJECT-16590746
[Patent] ＲＥＩＣ／Ｄｋｋ－３遺伝子を含むＥＧＦＲ遺伝子変異陽性肺癌の治療薬2022
- Inventor(s)
  公文裕巳, 大橋圭明, 木浦勝行他
- Industrial Property Rights Holder
  公文裕巳, 大橋圭明, 木浦勝行他
- Industrial Property Rights Type
  特許
- Filing Date
  2022
- Overseas
- Data Source
  KAKENHI-PROJECT-19H03667
[Presentation] Egfr改変肺癌マウスモデルを用いたosimertinibとnintedanibによる抗腫瘍効果の検討2023
- Author(s)
  栗林忠弘, 大橋圭明, 田岡征高, 森田絢子, 西達也, 西村淳, 大川祥, 中須賀崇匡, 平生敦子, 二宮貴一朗, 槇本剛, 藤井昌学, 市原英基, 堀田勝幸, 田端雅弘, 前田嘉信, 木浦勝行.
- Organizer
  第64回日本肺癌学会学術集会
- Data Source
  KAKENHI-PROJECT-23K24339
[Presentation] Egfr改変肺癌マウスモデルを用いたosimertinibとnintedanibによる抗腫瘍効果の検討2023
- Author(s)
  栗林忠弘, 大橋圭明, 田岡征高, 森田絢子, 西達也, 西村淳, 大川祥, 中須賀崇匡, 平生敦子, 二宮貴一朗, 槇本剛, 藤井昌学, 市原英基, 堀田勝幸, 田端雅弘, 前田嘉信, 木浦勝行.
- Organizer
  第64回日本肺癌学会学術集会
- Data Source
  KAKENHI-PROJECT-22K19529
[Presentation] Egfr肺癌に対しADU-S100はosimertinibが誘導する抗腫瘍免疫を増強する2023
- Author(s)
  西村淳, 大橋圭明, 栗林忠弘, 田岡征高, 大川祥, 中須賀崇匡, 西井和也, 平生敦子, 二宮貴一朗, 槇本剛, 藤井昌学, 市原英基,頼冠名, 堀田勝幸, 田端雅弘, 前田嘉信, 木浦勝行.
- Organizer
  第64回日本肺癌学会学術集会
- Data Source
  KAKENHI-PROJECT-23K24339
[Presentation] Egfr肺癌に対しADU-S100はosimertinibが誘導する抗腫瘍免疫を増強する2023
- Author(s)
  西村淳, 大橋圭明, 栗林忠弘, 田岡征高, 大川祥, 中須賀崇匡, 西井和也, 平生敦子, 二宮貴一朗, 槇本剛, 藤井昌学, 市原英基,頼冠名, 堀田勝幸, 田端雅弘, 前田嘉信, 木浦勝行.
- Organizer
  第64回日本肺癌学会学術集会
- Data Source
  KAKENHI-PROJECT-22K19529
[Presentation] Egfr変異陽性肺癌に対する Ad-SGE-REICと抗PD-1抗体併用による抗腫瘍免疫賦活効果2022
- Author(s)
  中須賀崇匡，大橋圭明，西井和也，平生敦子，大川祥，髙田健二，西村淳，栗林忠弘，安東千裕，西達也，森田絢子，槇本剛，二宮貴一朗，藤井昌学，市原英基，堀田勝幸，田端雅弘，前田嘉信，木浦勝行
- Organizer
  第63回日本肺癌学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03667
[Presentation] Egfr変異陽性肺癌に対する Ad-SGE-REICと抗PD-1抗体併用による抗腫瘍免疫賦活効果2022
- Author(s)
  中須賀崇匡，大橋圭明，西井和也，平生敦子，大川祥，髙田健二，西村淳，栗林忠弘，安東千裕，西達也，森田絢子，槇本剛，二宮貴一朗，藤井昌学，市原英基，堀田勝幸，田端雅弘，前田嘉信，木浦勝行
- Organizer
  第63回日本肺癌学会学術集会
- Data Source
  KAKENHI-PROJECT-23K24339
[Presentation] EGFR阻害が誘導するEgfr肺癌に対する抗腫瘍免疫を逐次的VEGFR-2/PD-1阻害が増強する2022
- Author(s)
  西井和也，大橋圭明，冨田秀太，中須賀崇匡，平生敦子，大川祥，西村淳，安東千裕，槇本剛，二宮貴一朗，加藤有加，久保寿夫，市原英基，堀田勝幸，田端雅弘，豊岡伸一，鵜殿平一郎，前田嘉信，木浦勝行
- Organizer
  第63回日本肺癌学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03667
[Presentation] EGFR阻害が誘導するEgfr肺癌に対する抗腫瘍免疫を逐次的VEGFR-2/PD-1阻害が増強する2022
- Author(s)
  西井和也，大橋圭明，冨田秀太，中須賀崇匡，平生敦子，大川祥，西村淳，安東千裕，槇本剛，二宮貴一朗，加藤有加，久保寿夫，市原英基，堀田勝幸，田端雅弘，豊岡伸一，鵜殿平一郎，前田嘉信，木浦勝行
- Organizer
  第63回日本肺癌学会学術集会
- Data Source
  KAKENHI-PROJECT-22K19529
[Presentation] Egfr変異陽性肺癌に対する Ad-SGE-REICと抗PD-1抗体併用による抗腫瘍免疫賦活効果2022
- Author(s)
  中須賀崇匡，大橋圭明，西井和也，平生敦子，大川祥，髙田健二，西村淳，栗林忠弘，安東千裕，西達也，森田絢子，槇本剛，二宮貴一朗，藤井昌学，市原英基，堀田勝幸，田端雅弘，前田嘉信，木浦勝行
- Organizer
  第63回日本肺癌学会学術集会
- Data Source
  KAKENHI-PROJECT-22K19529
[Presentation] EGFR阻害が誘導するEgfr肺癌に対する抗腫瘍免疫を逐次的VEGFR-2/PD-1阻害が増強する2022
- Author(s)
  西井和也，大橋圭明，冨田秀太，中須賀崇匡，平生敦子，大川祥，西村淳，安東千裕，槇本剛，二宮貴一朗，加藤有加，久保寿夫，市原英基，堀田勝幸，田端雅弘，豊岡伸一，鵜殿平一郎，前田嘉信，木浦勝行
- Organizer
  第63回日本肺癌学会学術集会
- Data Source
  KAKENHI-PROJECT-23K24339
[Presentation] Combined efect of Lorlatinib and Bcl-2 inhibitors in　intrinsic Alectinib resistant Lung Adenocarcinoma　Harboring the EML4-ALK Fusion Gene2021
- Author(s)
  Go Makimoto, Kadoaki Ohashi, Shuta Tomida, Kenji Takada, Hiromi Watanabe, Kazuya Nishii, Kiichiro Ninomiya, Yuka Kato, Toshio Kubo, Eiki Ichihara, Katsuyuki Hotta, Masahiro Tabata, Shinichi Toyooka, Yoshinobu Maeda and Katsuyuki Kiura
- Organizer
  1st JCA-AACR Precision Cancer Medicine International Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08625
[Presentation] Novel combined immunotherapy with EGFR-TKI follow by dual blockade of PD-1 and VGFR2 in lung cancer harboring Egfr mutation.2021
- Author(s)
  Kazuya Nishii,, Kadoaki Ohashi, Shuta Tomida, Takamasa Nakasuka, Atsuko Hirabae, Sachi Okawa, Hisao Higo, Hiromi Watanabe, Hirohisa Kano, Chihiro Ando, Go Makimoto, Kiichiro Ninomiya,et al and Heiichiro Udono, Yoshinobu Maeda, Katsuyuki Kiura
- Organizer
  1st JCA-AACR Precision Cancer Medicine International Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08625
[Presentation] Increased expression of amphiregulin may contribute to crizotinib resistance in lung cancer cells harboring ROS1 fusion genes2021
- Author(s)
  Hiromi Watanabe, Yuka Kato, Kadoaki Ohashi, Shuta Tomida, Kenji Takada, Kazuya Nishii, Go Makimoto, Kiichiro Ninomiya, Masanori Fujii, Toshio Kubo, Eiki Ichihara, Yoshinobu Maeda, Katsuyuki Kiura
- Organizer
  1st JCA-AACR Precision Cancer Medicine International Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08625
[Presentation] Combined effect of Lorlatinib and Bcl-2 inhibitors in　intrinsic Alectinib resistant Lung Adenocarcinoma　Harboring the EML4-ALK Fusion Gene2021
- Author(s)
  Go Makimoto, Kadoaki Ohashi, Shuta Tomida, Kenji Takada, Hiromi Watanabe, Kazuya Nishii, Kiichiro Ninomiya, Yuka Kato, Toshio Kubo, Eiki Ichihara, Katsuyuki Hotta, Masahiro Tabata, Shinichi Toyooka, Yoshinobu Maeda and Katsuyuki
- Organizer
  1st JCA-AACR Precision Cancer Medicine International Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03667
[Presentation] Novel combined immunotherapy with EGFR-TKI followed by dual blockade of PD-1 and VEGFR2 in lung cancer harboring Egfr mutation.2021
- Author(s)
  Kazuya Nishii, Kadoaki Ohashi, Shuta Tomida, et al, and Shinichi Toyooka, Heiichiro Udono, Yoshinobu Maeda, Katsuyuki Kiura
- Organizer
  1st JCA-AACR Precision Cancer Medicine International Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03667
[Presentation] Increased expression of amphiregulin may contribute to crizotinib resistance in lung cancer cells harboring ROS1 fusion genes2021
- Author(s)
  Hiromi Watanabe, Yuka Kato, Kadoaki Ohashi, Shuta Tomida, Kenji Takada, Kazuya Nishii, Go Makimoto, Kiichiro Ninomiya, Masanori Fujii, Toshio Kubo, Eiki Ichihara, Yoshinobu Maeda, Katsuyuki Kiura
- Organizer
  1st JCA-AACR Precision Cancer Medicine International Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03667
[Presentation] EGFR遺伝子変異陽性進行肺癌に対する治療状況に関する前向きレジストリ研究2020
- Author(s)
  西井和也, (中尾美香, 石川暢久, 益田武), 藤本伸一, (山﨑正弘), 瀧川奈義夫, (小谷昌広), 藤原慶一, (窪田哲也, 井上政昭), 上月稔幸, (上田裕), 久山彰一, 堀田勝幸, 木浦勝行
- Organizer
  第61回日本肺癌学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03667
[Presentation] Egfr改変肺癌マウスモデルを用いたAd-SGE-REICの抗腫瘍効果の検討2020
- Author(s)
  中須賀崇匡, 大橋圭明, 西井和也, 平生敦子, 大川祥, 安東千裕, 原尚史, 狩野裕久, 渡邉洋美, 二宮貴一朗, 加藤有加, 二宮崇, 久保寿夫, 頼冠名, 市原英基, 堀田勝幸, 田端雅弘, 前田嘉信, 木浦勝行
- Organizer
  第61回日本肺癌学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03667
[Presentation] Egfr改変肺癌マウスモデルを用いたpersisterがん細胞に対する根治的薬物療法の開発2020
- Author(s)
  大川祥，大橋圭明，原尚史，西井和也，中須賀崇匡，平生敦子，安東千裕，狩野裕久，渡邉洋美，二宮貴一朗，加藤有加，久保寿夫，頼冠名，市原英基，堀田勝幸，田端雅弘，前田嘉信，木浦勝行
- Organizer
  第61回日本肺癌学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03667
[Presentation] Egfr改変肺癌マウスモデルを用いたEGFR-TKI、抗VEGFR-2抗体と抗PD-1抗体併用療法の検討2020
- Author(s)
  西井和也, 大橋圭明, 中須賀崇匡, 平生敦子, 大川祥, 渡邉洋美, 狩野裕久, 原尚史, 安東千裕, 二宮貴一朗, 加藤有加, 二宮崇, 久保寿夫, 頼冠名, 市原英基, 堀田勝幸, 田端雅弘, (鵜殿平一郎 ), 前田嘉信, 木浦勝行
- Organizer
  第61回日本肺癌学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03667
[Presentation] Egfr改変肺癌マウスモデルを用いたEGFR-TKI、抗VEGFR-2抗体と抗PD-1抗体併用療法の検討2020
- Author(s)
  西井和也, 大橋圭明, 中須賀崇匡, 平生敦子, 大川祥, 渡邉洋美, 狩野裕久, 原尚史, 安東千裕, 二宮貴一朗, 加藤有加, 二宮崇, 久保寿夫, 頼冠名, 市原英基, 堀田勝幸, 田端雅弘, (鵜殿平一郎 ), 前田嘉信, 木浦勝行
- Organizer
  第61回日本肺癌学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08625
[Presentation] 免疫チェックポイント阻害薬が有効なEGFR遺伝子変異陽性肺癌の特徴2020
- Author(s)
  市原英基, 原田大二郎, 井上考司, 柴山卓夫, 細川忍, 岸野大蔵, 張田信吾, 越智宣昭, 小田尚廣, 原尚史, 堀田勝幸, 前田嘉信, 木浦勝行
- Organizer
  第61回日本肺癌学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03667
[Presentation] Egfr改変肺癌マウスモデルを用いたpersisterがん細胞に対する根治的薬物療法の開発2020
- Author(s)
  大川祥，大橋圭明，原尚史，西井和也，中須賀崇匡，平生敦子，安東千裕，狩野裕久，渡邉洋美，二宮貴一朗，加藤有加，久保寿夫，頼冠名，市原英基，堀田勝幸，田端雅弘，前田嘉信，木浦勝行
- Organizer
  第61回日本肺癌学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08625
[Presentation] Tumor immunoediting in a lung cancer mouse model harboring EGFR mutations2019
- Author(s)
  Kazuya Nishii, Kadoaki Ohashi, Kiichiro Ninomiya, Go Makimoto, Hiromi Watanabe, Hirohisa Kano, Naofumi Hara, Heiichiro Udono and Katsuyuki Kiura
- Organizer
  American Association for Cancer Research (AACR) 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08625
[Presentation] Tumor immunoediting in a lung cancer mouse model harboring EGFR mutations2019
- Author(s)
  Kazuya Nishii, Kadoaki Ohashi, Kiichiro Ninomiya, Go Makimoto, Hiromi Watanabe, Hirohisa Kano, Naofumi Hara, Heiichiro Udono and Katsuyuki Kiura
- Organizer
  American Association for Cancer Research (AACR)　annual meeting 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03667
[Presentation] Rapid acquired resistance to alectinib in ALK-positive lung cancers with high tumor mutation burden2019
- Author(s)
  Kadoaki Ohashi, Go Makimoto, Shuta Tomida, Kazuya Nishii, Shinichi Toyooka and Katsuyuki Kiura
- Organizer
  American Association for Cancer Research (AACR) 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08625
[Presentation] In vivo efficacy of triplet therapy with osimertinib, cetuximab and bevacizumab for lung cancer cells harboring EGFR T790M2018
- Author(s)
  Kazuya Nishii, Kadoaki Ohashi, Go Makimoto, Hisao Higo, Kiichiro Ninomiya, Hiroe Kayatani, Takashi Ninomiya, Toshio Kubo, Kammei Rai, Eiki Ichihara, Katsuyuki Hotta, Masahiro Tabata, Katsuyuki Kiura
- Organizer
  AACR Annual Meeting 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04830
[Presentation] Novel Syngenic Lung Cancer Mouse Model Harboring EGFR Mutations2018
- Author(s)
  Kazuya Nishii, Kadoaki Ohashi, Hisao Higo, Kenichiro Kudo, Go Makimoto, Hiroe Kayatani, Hiromi Watanabe, Kiichiro Ninomiya, Takashi Ninomiya, Toshio Kubo, Kammei Rai, Eiki Ichihara, Katsuyuki Hotta, Masahiro Tabata, Katsuyuki Kiura
- Organizer
  The 6th JCA-AACR Special Joint Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04830
[Presentation] The novel osimertinib resistant lung cancer mice model harboring EGFR mutations driven by the SP-C promoter2018
- Author(s)
  Kadoaki Ohashi, Hisao Higo, Go Makimoto, Kenichiro Kudo, Kazuya Nishii, Kiichiro Ninomiya, Hiroe Kayatani, Takashi Ninomiya, Toshio Kubo, Kammei Rai, Eiki Ichihara, Katsuyuki Hotta, Masahiro Tabata, Katsuyuki Kiura
- Organizer
  AACR Annual Meeting 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04830
[Presentation] EGFR変異陽性NSCLCに対するafatinib・bevacizumab併用療法の第I相試験：OLCSG14042018
- Author(s)
  青江啓介、近森研一、前田忠士、亀井治人、二宮崇、野上尚之、別所昭宏、久山彰一、藤本伸一、杉本啓介、瀧川奈義夫、木浦勝行
- Organizer
  第58回日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-15H04830
[Presentation] Analysis of the Rapid Acquired Resistance of ALK-positive Lung Cancers to Alectinib: A Comprehensive Study Using Autopsied Specimens and Patient-derived Cell Lines2018
- Author(s)
  Go Makimoto, Kadoaki Ohashi, Kazuya Nishii, (Shuta Tomida), Hiroe Kayatani, Hisao Higo, Kiichiro Ninomiya, Hiromi Watanabe, Takashi Ninomiya, Toshio Kubo, Eiki Ichihara, Akiko Sato, Katsuyuki Hotta, Masahiro Tabata, (Sinichi Toyooka), Yoshinobu Maeda, Katsuyuki Kiura
- Organizer
  The 6th JCA-AACR Special Joint Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04830
[Presentation] A comprehensive analysis of autopsied specimens and patient-derived cell lines in ALK-positive lung cancers with rapid acquired resistance to alectinib2017
- Author(s)
  Go Makimoto, Kadoaki Ohashi, Kazuya Nishii, Shuta Tomida, Hiroe Kayatani, Tomoki Tamura, Hisao Higo, Kiichiro Ninomiya, Takashi Ninomiya, Toshio Kubo, Eiki Ichihara, Akiko Sato, Katsuyuki Hotta, Masahiro Tabata, Katsuyuki Kiura
- Organizer
  AACR Annual Meeting 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04830
[Presentation] Clinical Characteristics of Japanese Candidates for Lung Transplant Due to Interstitial Lung Disease and Risk Factors for Early Death While on the Waiting List2017
- Author(s)
  Hisao Higo , Eiki Ichihara , Takeshi Kurosaki , Kentaroh Miyoshi , Toshio Kubo , Shinji Otani , Seiichiro Sugimoto , Masaomi Yamane , Nobuaki Miyahara , Katsuyuki Kiura , Takahiro Oto
- Organizer
  American Thoracic Society 2017 International Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15458
[Presentation] Acquired resistance to the third-generation EGFR inhibitor ASP8273 is associated with MET or NRAS gene amplifications in preclinical models2017
- Author(s)
  Kiichiro Ninomiya, Kadoaki Ohashi, Shuta Tomida, Hiroe Kayatani, Tomoki Tamura, Hisao Higo, Go Makimoto, Takashi Ninomiya, Toshio Kubo, Eiki Ichihara, Akiko Sato, Katsuyuki Hotta, Masahiro Tabata, Katsuyuki Kiura.
- Organizer
  AACR Annual Meeting 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04830
[Presentation] Clinical Characteristics of Japanese Candidates for Lung Transplant Due to Interstitial Lung Disease and Risk Factors for Early Death While on the Waiting List2017
- Author(s)
  Hisao Higo , Eiki Ichihara , Takeshi Kurosaki , Kentaroh Miyoshi , Toshio Kubo , Shinji Otani , Seiichiro Sugimoto , Masaomi Yamane , Nobuaki Miyahara , Katsuyuki Kiura , Takahiro Oto
- Organizer
  American Thoracic Society 2017 International Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04830
[Presentation] A comprehensive analysis of autopsied specimens and patient-derived cell lines in ALK-positive lung cancers with rapid acquired resistance to alectinib2017
- Author(s)
  Go Makimoto, Kadoaki Ohashi, Kazuya Nishii, Shuta Tomida, Hiroe Kayatani, Tomoki Tamura, Hisao Higo, Kiichiro Ninomiya, Takashi Ninomiya, Toshio Kubo, Eiki Ichihara, Akiko Sato, Katsuyuki Hotta, Masahiro Tabata, Katsuyuki Kiura
- Organizer
  AACR Annual Meeting 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15458
[Presentation] Acquired resistance to the third-generation EGFR inhibitor ASP8273 is associated with MET or NRAS gene amplifications in preclinical models2017
- Author(s)
  Kiichiro Ninomiya, Kadoaki Ohashi, Shuta Tomida, Hiroe Kayatani, Tomoki Tamura, Hisao Higo, Go Makimoto, Takashi Ninomiya, Toshio Kubo, Eiki Ichihara, Akiko Sato, Katsuyuki Hotta, Masahiro Tabata, Katsuyuki Kiura.
- Organizer
  AACR Annual Meeting 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15458
[Presentation] Abstract 4667: pCR induced by triplet therapy with low-dose afatinib, cetuximab and bevcizumab in lung cancer cells harboring EGFR T790M2016
- Author(s)
  AKadoaki Ohashi, Kenichiro Kudo, Eiki Ichihara, Hiroe Kayatani, Hisao Higo, Yuka Kato, Yasuko Kurata, Daisuke Minami, Takashi Ninomiya, Toshio Kubo, Katsuyuki Hotta, Mitsune Tanimoto, Katsuyuki Kiura
- Organizer
  AACR 2016
- Place of Presentation
  Ernest N. Morial Convention Center New Orleans, Louisiana
- Year and Date
  2016-04-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04830
[Presentation] Abstract 1889: AXL and EGFR signaling mediate resistance to Crizotinib in non-small cell lung cancer cells harboring the ROS1 fusion gene2016
- Author(s)
  Yuka Kato, Kadoaki Ohashi, Eiki Ichihara, Shuuta Tomida, Hiroe Kayatani, Kenichiro Kudo, Daisuke Minami, Takashi Ninomiya, Toshio Kubo, Toshiyuki Kozuki, Katsuyuki Hotta, Nagio Takigawa, Mitsune Tanimoto, Katsuyuki Kiura
- Organizer
  AACR 2016
- Place of Presentation
  Ernest N. Morial Convention Center New Orleans, Louisiana
- Year and Date
  2016-04-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04830
[Presentation] Abstract 250: Interleukin-6 as potential predictive marker for therapeutic effect of Gefitinib in patients with advanced non-small-cell lung cancer harboring EGFR mutations2016
- Author(s)
  Tomoki Tamura, Katsuyuki Hotta, Yuka Kato, Takehiro Tanaka, Kouichi Ichimura, Kadoaki Oohashi, Takashi Ninomiya, Toshio Kubo, Eiki Ichihara, Mitsune Tanimoto, Katsuyuki Kiura
- Organizer
  AACR 2016
- Place of Presentation
  Ernest N. Morial Convention Center New Orleans, Louisiana
- Year and Date
  2016-04-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04830
[Presentation] Second primary cancer in survivors of locally advanced NSCLC treated with concurrent chemoradiation followed by surgery.2016
- Author(s)
  Go Makimoto, Toshio Kubo, Yuka Kato, Takashi Ninomiya, Isao Oze, Kadoaki Ohashi, Eiki Ichihara, Katsuyuki Hotta, Masahiro Tabata, Nagio Takigawa, Shinichi Toyooka, Kuniaki Katsui, Mitsune Tanimoto, Katsuyuki Kiura
- Organizer
  2016 ASCO Annual Meeting
- Place of Presentation
  Chicago
- Year and Date
  2016-06-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15458
[Presentation] Abstract 5198: Combination effect of anti-VEGFR-2 antibody with erlotinib on EGFR mutant non-small cell lung cancer2016
- Author(s)
  Hiroe Kayatani, Kadoaki Ohashi, Takeshi Imao, Kenichiro Kudo, Yuka Kato, Takashi Ninomiya, Toshio Kubo, Akiko Sato, Ktsuyuki Hotta, Mitsune Tanimoto, Katsuyuki Kiura
- Organizer
  AACR 2016
- Place of Presentation
  Ernest N. Morial Convention Center New Orleans, Louisiana
- Year and Date
  2016-04-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04830
[Presentation] Molecular Profiling of Idiopathic Pulmonary Fibrosis2016
- Author(s)
  肥後　寿夫、木浦　勝行
- Organizer
  第2回　呼吸器基礎研究を加速するための若手研究会
- Place of Presentation
  国立京都国際会館
- Data Source
  KAKENHI-PROJECT-16K15458
[Presentation] Abstract 4675: Synergistic effect of pacritinib with erlotinib on JAK2-mediated resistance in epidermal growth factor receptor mutation-positive non-small cell lung cancer2016
- Author(s)
  Nobuaki Ochi, Hideko Isozaki, Masami Takeyama, Jack W. Singer, Hiromichi Yamane, Yoshihiro Honda, Katsuyuki Kiura, Nagio Takigawa
- Organizer
  AACR 2016
- Place of Presentation
  Ernest N. Morial Convention Center New Orleans, Louisiana
- Year and Date
  2016-04-16
- Data Source
  KAKENHI-PROJECT-15H04830
[Presentation] Interleukin-6 Is a Valuable Predictive Marker for Therapeutic Effect of Gefitinib in Patients with Advanced NSCLC Harboring EGFR Mutations2015
- Author(s)
  Y. Kato, K. Hotta, T. Tamura, T. Tanaka, K. Ichimura, K. Ohashi, T. Kubo, E. Ichihara, M. Tanimoto, K. Kiura
- Organizer
  第16回世界肺癌会議
- Place of Presentation
  米国コロラド州デンバー
- Year and Date
  2015-09-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26430163
[Presentation] Non-invasive EGFR T790M detection using droplet digital PCR system2015
- Author(s)
  Shinsuke Hashida, Kadoaki Ohashi, Takehiro Matsubara, Tomoaki Ohtsuka, Mototsugu Watanabe1, Ken Suzawa1, Yuho Maki, Hiromasa Yamamoto, Junichi Soh, Hiroaki Asano1, Kazunori Tsukuda1, Shinichiro Miyoshi1, Katsuyuki Kiura1, Shinichi Toyooka1
- Organizer
  The 106th Annual Meeting of the American Association for Cancer Research
- Place of Presentation
  Philadelphia, PA, USA
- Year and Date
  2015-04-22
- Data Source
  KAKENHI-PROJECT-23390221
[Presentation] The impact of bevacizumab on combination low-dose afatinib and cetuximab therapy in lung cancer cells harboring activated EGFR mutations2015
- Author(s)
  Kenichiro Kudo, Sr., Kadoaki Ohashi, Eiki Ichihara, Daisuke Minami, Hisao Kubo, Akiko Sato, Yuka Kato, Hideko Isozaki, Hiroe Kayatani, Tomoki Tamura, Mitsune Tanimoto, Katsuyuki Kiura.
- Organizer
  The 106th Annual Meeting of the American Association for Cancer Research
- Place of Presentation
  Philadelphia, PA, USA
- Year and Date
  2015-04-20
- Data Source
  KAKENHI-PROJECT-23390221
[Presentation] Both programmed cell death protein 1 and programmed death-ligand 1 molecules can be expressed on the cell surface of small-cell lung cancer2015
- Author(s)
  Hiromichi Yamane1, Hideko Isozaki2, Nobuaki Ochi1, Kenichiro Kudo2, Yoshihiro Honda1, Tomoko Yamagishi1, Toshio Kubo2, Katsuyuki Kiura2, Nagio Takigawa1.Hiromichi Yamane1, Hideko Isozaki2, Nobuaki Ochi1, Kenichiro Kudo2, Yoshihiro Honda1, Tomoko Yamagishi1, Toshio Kubo2, Katsuyuki Kiura2, Nagio Takigawa1.
- Organizer
  The 106th Annual Meeting of the American Association for Cancer Research
- Place of Presentation
  Philadelphia, PA, USA
- Year and Date
  2015-04-20
- Data Source
  KAKENHI-PROJECT-23390221
[Presentation] ALK inactivation induced acquired resistance to alectinib in lung cancer harboring EML4-ALK fusion gene2014
- Author(s)
  Isozaki H, Ichihara E, Yasugi M, Ochi N, Hotta K, Takigawa N, Sendo T, Tanimoto M, Kiura K.
- Organizer
  Annual Meeting of the American Association for Cancer Research
- Place of Presentation
  USA, San Diego, San Diego Convention Center
- Year and Date
  2014-04-06
- Data Source
  KAKENHI-PROJECT-24591182
[Presentation] ALK inactivation induced acquired resistance to alectinib in lung cancer harboring EML4-ALK fusion gene.2014
- Author(s)
  Hideko Isozaki, Eiki Ichihara, Masayuki Yasugi, Ocihi Nobuaki, Katsuyuki Hotta, Nagio Takigawa, Toshiaki Sendo, Mitsune Tanimoto, Katsuyuki Kiura
- Organizer
  The 105th Annual Meeting of the American Association for Cancer Research
- Place of Presentation
  San Diego, CA. USA
- Year and Date
  2014-04-08
- Data Source
  KAKENHI-PROJECT-23390221
[Presentation] Novel germline G660D mutation in HER2 gene detected by whole-exome sequencing can predispose a patient to developing familial lung adenocarcinoma2014
- Author(s)
  Hiromasa Yamamoto, Koichiro Higasa, Masakiyo Sakaguchi, Kazuhiko Shien, Junichi Soh, Koichi Ichimura, Masashi Furukawa, Shinsuke Hashida, Kazunori Tsukuda, Nagio Takigawa, Keitaro Matsuo, Katsuyuki Kiura, Sinichiro Miyoshi, Fumihiko Matsuda, Shinichi Toyooka
- Organizer
  The 105th Annual Meeting of the American Association for Cancer Research
- Place of Presentation
  San Diego, CA. USA
- Year and Date
  2014-04-09
- Data Source
  KAKENHI-PROJECT-23390221
[Presentation] Epidermal growth factor receptor signaling conferred acquired crizotinib resistance to a non-small cell lung cancer cell line harboring the SLC34A2-ROS1 fusion gene2014
- Author(s)
  Kato Y, Ohashi K, Ichihara E, Isozaki H, Kudo K, Minami D, Kubo T, Sato A, Hotta K, Tabata M, Takigawa N, Tanimoto M, Kiura K
- Organizer
  Annual Meeting of the European Society for Medical Oncology
- Place of Presentation
  Spain, Madrid, Feria de Madrid
- Year and Date
  2014-09-28
- Data Source
  KAKENHI-PROJECT-24591182
[Presentation] PTEN deficient lung cancer cells are sensitive to the combination of olaparib with cisplatin through suppressing DNA damage signaling2013
- Author(s)
  Minami Daisuke, Takigawa Nagio, Takeda Hiromasa, Takata Minoru, Ochi Nobuaki , Ichihara Eiki, Hisamoto Akiko, Hotta Katsuyuki, Tanimoto Mitsune, Kiura Katsuyuki
- Organizer
  AACR Annual Meeting 2013
- Place of Presentation
  Washington Convention Center, Washington, DC, USA
- Data Source
  KAKENHI-PROJECT-24591182
[Presentation] Knockdown of EGFR to investigate its therapeutic potential for treatment of non-small cell lung cancers2012
- Author(s)
  Junichi Soh, Kazuhiko Shien, Tsuyoshi Ueno, Norimitsu Tanaka, Hiromasa Yamamoto, Katsuyuki Kiura, Tetsuya Mitsudomi, Shinichi Toyooka, Shinichiro Miyoshi
- Organizer
  AACR Annual Meeting 2012
- Place of Presentation
  McCormick Place in Chicago, Illinois
- Data Source
  KAKENHI-PROJECT-23390221
[Presentation] Prognostic impact of cancer stem cell-related markers in non-small cell lung cancer patients treated with induction chemoradiotherapy2012
- Author(s)
  Kazuhiko Shien, Shinichi Toyooka, Kouichi Ichimura, Junichi Soh, Takahiro Oto, Katsuyuki Kiura,
- Organizer
  AACR Annual Meeting 2012
- Place of Presentation
  McCormick Place in Chicago, Illinois
- Data Source
  KAKENHI-PROJECT-23390221
[Presentation] RAS signaling pathway gene mutations and acquired resistance to EGFR tyrosine-kinase inhibitors in EGFR mutant lung cancer2012
- Author(s)
  Kadoaki Ohashi, Juliann Chmielecki, Ya-Lun Lin, Shinichi Toyooka, Katsuyuki Kiura, Roman Thomas, James Chih-Hsin Yang, Vincent Miller, Marc Ladanyi, Katerina Politi, William Pao1
- Organizer
  AACR Annual Meeting 2012
- Place of Presentation
  McCormick Place in Chicago, Illinois
- Data Source
  KAKENHI-PROJECT-23390221
[Presentation] Effect of AZD1480 on lung tumor in transgenic mice carrying activating EGFR mutation2012
- Author(s)
  Toshi Murakami, Nagio Takigawa, Takashi Ninomiya, Nobuhiro Honda, Hideko Isozaki, Eiki Ichihara, Akiko Hisamoto, Katsuyuki Hotta, Mitsune Tanimoto, Katsuyuki Kiura
- Organizer
  AACR Annual Meeting 2012
- Place of Presentation
  McCormick Place in Chicago, Illinois
- Data Source
  KAKENHI-PROJECT-23390221
[Presentation] Afatinib prolonged survival in EGFR-driven lung cancer model compared to gefitinib2012
- Author(s)
  Takashi Ninomiya, Eiki Ichihara, Akiko Hisamoto, Katsuyuki Hotta, Mitsune Tanimoto, Katsuyuki Kiura, Nagio Takigawa, Nobuaki Ochi, Masayuki Yasugi, Daijiro Harada.
- Organizer
  AACR Annual Meeting 2012
- Place of Presentation
  McCormick Place in Chicago, Illinois
- Data Source
  KAKENHI-PROJECT-23390221
[Presentation] Effect of everolimus on lung tumorigenesis in transgenic mice carrying activating EGFR mutation2011
- Author(s)
  Yasugi Masayuki, Takigawa Nagio, Ochi Nobuaki, Ichihara Eiki, Hisamoto Akiko, Hotta Katsuyuki, Tanimoto Mitsune, Kiura Katsuyuki
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋市
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-21590995
[Presentation] Effect of everolimus on lung tumorigenesis in transgenic mice carrying activating EGFR mutation2011
- Author(s)
  Yasugi Masayuki, Takigawa Nagio, Ochi Nobuaki, Ichihara Eiki, Hisamoto Akiko, Hotta Katsuyuki, Tabata Masahiro, Tanimoto Mitsune, Kiura Katsuyuki
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場(名古屋市)
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-21590995
[Presentation] エクソン19欠失EGFR遺伝子変異陽性肺癌モデルに対するアファチニブの効果2011
- Author(s)
  二宮崇, 瀧川奈義夫, 村上斗司, 本多宣裕, 南大輔, 越智宣昭, 八杉昌幸, 久保寿夫, 市原英基, 谷本光音, 木浦勝行
- Organizer
  第52回日本肺癌学会総会
- Place of Presentation
  大阪市
- Year and Date
  2011-11-04
- Data Source
  KAKENHI-PROJECT-21590995
[Presentation] Effect of everolimus on lung tumorigenesis in transgenic mice carrying activating EGFR mutation2011
- Author(s)
  Yasugi M, Takigawa N, Kiura K, et al
- Organizer
  第102回米国癌学会(AACR)
- Place of Presentation
  オーランド,フロリダ,アメリカ合衆国
- Year and Date
  2011-04-05
- Data Source
  KAKENHI-PROJECT-21659209
[Presentation] Role of ERK reactivation mediated by Src in acquired resistance to gefitinib in non-small cell lung cancer with EGFR mutation2011
- Author(s)
  Ochi N, Takigawa N, Ohashi K, Takeda H, Fujii M, Kubo T, Ichihara E, Hotta K, Tanimoto M, Kiura K
- Organizer
  AACR Annual Meeting 2011
- Place of Presentation
  Orange County Convention Center, Orlando, FL, USA
- Year and Date
  2011-04-03
- Data Source
  KAKENHI-PROJECT-23390221
[Presentation] Vascular endothelial growth factor receptor tyrosine kinase inhibitor inhibited mutated epidermal growth factor receptor-driven tumors ex vivo and in vivo2011
- Author(s)
  Kubo T, Ohashi K, Osawa M, Takeda H, Ichihara E, Ninomiya T, Takigawa N, Harita S, Nakata Y, Tanimoto M, Kiura K
- Organizer
  AACR Annual Meeting 2011
- Place of Presentation
  Orange County Convention Center, Orlando, FL, USA
- Year and Date
  2011-04-05
- Data Source
  KAKENHI-PROJECT-23390221
[Presentation] ERK reactivation mediated by SRC in acquired resistance to gefitinib in non-small cell lung cancer with EGFR mutation2011
- Author(s)
  Ochi Nobuaki, Takigawa Nagio, Yasugi Masayuki, Ichihara Eiki, Hisamoto Akiko, Hotta Katsuyuki, Tabata Masahiro, Tanimoto Mitsune, Kiura Katsuyuki
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋市
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-21590995
[Presentation] エクソン19欠失EGFR遺伝子変異陽性肺癌モデルに対するアファチニブの効果2011
- Author(s)
  二宮崇, 瀧川奈義夫, 村上斗司, 本多宣裕, 南大輔, 越智宣昭, 八杉昌幸, 久保寿夫, 市原英基, 谷本光音, 木浦勝行
- Organizer
  第52回日本肺癌学会総会
- Place of Presentation
  大阪国際会議場(大阪市)
- Year and Date
  2011-11-04
- Data Source
  KAKENHI-PROJECT-21590995
[Presentation] 肺がん治療の進歩2011
- Author(s)
  木浦勝行
- Organizer
  第45回日本内科学会近畿支部生涯教育講演会
- Place of Presentation
  京都テルサ,京都
- Year and Date
  2011-12-17
- Data Source
  KAKENHI-PROJECT-23390221
[Presentation] JAK2/STAT3 induces erlotinib-resistance in lung cancer cells harboring EGFR-activating mutations2011
- Author(s)
  Harada D, Takigawa N, Onashi K, Tchihara E, Toshio Kubo T, Takeda H, Kashihara H, Tanimoto M, Kiura K
- Organizer
  AACR Annual Meeting 2011
- Place of Presentation
  Orange County Convention Center, Orlando, FL, USA
- Year and Date
  2011-04-03
- Data Source
  KAKENHI-PROJECT-23390221
[Presentation] Multiple molecular targeting effects by miR-7 in EGFR tyrosine kinase inhibitor-resistant lung cancer xenograft models2011
- Author(s)
  Kammei Rai, Takigawa Nagio, Ito Sachio, Kiura Katsuyuki, Yasuda Tatsuji, Shimizu Kenji, Tanimoto Mitsune
- Organizer
  102nd Annual Meeting of American Association for Cancer Research
- Place of Presentation
  Orlando, USA
- Year and Date
  2011-04-04
- Data Source
  KAKENHI-PROJECT-21590995
[Presentation] ERK reactivation mediated by SRC in acquired resistance to gefitinib in non-small cell lung cancer with EGFR mutation2011
- Author(s)
  Ochi Nobuaki, Takigawa Nagio, Yasugi Masayuki, Ichihara Eiki, Hisamoto Akiko, Hotta Katsuyuki, Tabata Masahiro, Tanimoto Mitsune, Kiura Katsuyuki
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場(名古屋市)
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-21590995
[Presentation] JAK2/STAT3 induces erlotinib-resistance in lung cancer cells harboring EGFR-activating mutations2011
- Author(s)
  Harada Daijiro, Takigawa Nagio, Ohashi Kadoaki, Ichihara Eiki, Kubo Toshio, Takeda Hiromasa, Kashihara Hiromi, Hotta Katsuyuki, Tanimoto Mitsune, Kiura Katsuyuki
- Organizer
  102nd Annual Meeting of American Association for Cancer Research
- Place of Presentation
  Orlando, USA
- Year and Date
  2011-04-03
- Data Source
  KAKENHI-PROJECT-21590995
[Presentation] Effect of afatinib on lung cancer burden induced by an exon 19 EGFR mutation in transgenic mice2011
- Author(s)
  Ninomiya T, Takigawa N, Kubo T, Yasugi M, Honda Y, Minami D, Murakami T, Ichihara E, Tanimoto M, Kiura K
- Organizer
  AACR Annual Meeting 2011
- Place of Presentation
  Orange County Convention Center, Orlando, FL, USA
- Year and Date
  2011-04-05
- Data Source
  KAKENHI-PROJECT-23390221
[Presentation] Lipofection of the designed plasmid expressing microRNA-7 has antitumor effect in gefitinib-resistant lung adenocarcinoma in vivo.2010
- Author(s)
  Rai K, Takigawa N, Ito S, Kashihara H, Ichihara E, Kiura K, Yasuda T, Shimizu K, Tanimoto M.
- Organizer
  米国癌学会
- Place of Presentation
  ワシントンDC
- Year and Date
  2010-04-20
- Data Source
  KAKENHI-PROJECT-21590995
[Presentation] Chemopreventive effect of vandetanib on tumorigenesis in a mouse model of non-smoking related lung cancer AACR Annual Meeting 20092009
- Author(s)
  Kubo T, Ohashi K, Osawa M, Takeda H, Ichihara E, Fujii M, Kashihara H, Takigawa N, Tanimoto , Kiura K
- Organizer
  Biological Mechanisms and Molecular Markers of Prevention(米国癌学会総会, ミニシンポジウム)
- Place of Presentation
  Colorado Convention Center, Denver, CO Abstract#4783 Minisymposium
- Data Source
  KAKENHI-PROJECT-19590895
[Presentation] The role of STAT3 in the progression of lung adenocarcinoma2009
- Author(s)
  Takata S, Takigawa N, Kiura K, et al.
- Organizer
  第68回日本癌学会総会
- Place of Presentation
  横浜市
- Year and Date
  2009-10-02
- Data Source
  KAKENHI-PROJECT-21590995
[Presentation] Chemopreventive effect of vandetanib on tumorigenesis in a mouse model of non-smoking related lung cancer2009
- Author(s)
  Kubo T, Ohashi K, Osawa M, Takeda H, Ichihara E, Fujii M, Kashihara H, Takigawa N, Tanimoto, Kiura K.
- Organizer
  米国癌学会総会 AACR Annual Meeting 200 Abstract#4783 Minisymposium
- Place of Presentation
  Colorado Convention Center, Denver, CO, USA
- Data Source
  KAKENHI-PROJECT-21659209
[Presentation] すりガラス陰影を伴う肺腺癌の進展におけるEGFRシグナルの関与発表者2008
- Author(s)
  高田三郎、瀧川奈義夫、大橋圭明、畝川芳彦、山下素弘、寺本典弘、新海哲、上月稔幸、堀田勝幸、田端雅弘、木浦勝行、谷本光音
- Organizer
  第49回日本肺癌学会総会
- Year and Date
  2008-11-13
- Data Source
  KAKENHI-PROJECT-18590851
[Presentation] すりガラス陰影を伴う肺腺癌の進展におけるEGFRシグナルの関与2008
- Author(s)
  高田三郎, 瀧川奈義夫, 大橋圭明, 畝川芳彦, 山下素弘, 寺本典弘, 新海哲, 上月稔幸, 堀田勝幸, 田端雅弘, 木浦勝行, 谷本光音
- Organizer
  第49回日本肺癌学会総会
- Place of Presentation
  北九州市
- Year and Date
  2008-11-13
- Data Source
  KAKENHI-PROJECT-18590851
[Presentation] Chemopreventive effect of gefitinib on tumorgenesis in smoking unrelated lung cancer mouse model (Abstract # 4186 Minisymposium)2008
- Author(s)
  Ohashi K, Kiura K, Osawa M., et al.
- Organizer
  AACR Annual Meeting 2008 (2008年米国癌学会)
- Place of Presentation
  San Diego, CA
- Data Source
  KAKENHI-PROJECT-19590895
[Presentation] Chemopreventive effect of gefitinib on tumorgenesis in smoking unrelated lung cancer mouse model AACR Annual Meeting 20082008
- Author(s)
  Ohashi K, Kiura K, Osawa M, Takeda H, Kubo T, Ichihara E, Takigawa N, Hirano S, Tanimoto M, Takata M
- Organizer
  米国癌学会総会, ミニシンポジウム
- Place of Presentation
  San Diego, CA Abstract # 4186 Minisymposium
- Data Source
  KAKENHI-PROJECT-19590895
[Presentation] Transgenic mice with mouse EGFR mutation developed lung adenocarcinoma.2007
- Author(s)
  Ohashi K, Rai K, Kiura K, Osawa M, Hirano S, Fujiwara Y, Yoshino T, Takigawa N, Takata M, Tanimoto M
- Organizer
  2007 AACR Annual Meeting 米国癌学会
- Place of Presentation
  Los Angeles, CA, 米国
- Year and Date
  2007-04-17
- Data Source
  KAKENHI-PROJECT-19590895
[Presentation] Emergence of EGFR T790M mutation during chronic exposure to gefitinib in a NSCLC cell line2007
- Author(s)
  Ogino A, Kitao H, Hirano S, Uchida A, Takigawa N, Kiura K, Tanimoto M
- Organizer
  98^<th> Annual Meeting of American Association for Cancer Research
- Place of Presentation
  LA, USA
- Year and Date
  2007-04-16
- Data Source
  KAKENHI-PROJECT-18590851
[Presentation] Early occurrence of epidermal growth factor receptor Mutation in lung adenocarcinoma: Comparison between pulmonary atypical adenomatous hyperplasia and adenocarcinoma2006
- Author(s)
  Kozuki T, Hisamoto A, Takigawa N, Tabata M, Segawa Y, Nakata M, Umemura S, Ohashi K, Kiura K, Eguchi K, Ueoka H, Tanimoto M
- Organizer
  97^<th> Annual Meeting of American Association for Cancer Research
- Place of Presentation
  Washington DC, USA
- Year and Date
  2006-04-17
- Data Source
  KAKENHI-PROJECT-18590851
[Presentation] Acquired Resistance to a New ALK Inhibitor, Alectinib in Lung Cancer
- Author(s)
  Hideko Isozaki, Eiki Ichihara, Kadoaki Ohashi, Ochi Nobuaki, Toshio Kubo, Daisuke Minami, Hiromichi Yamane, Akiko-Hisamoto Sato, Kenichiro Kudo, Yuka Kato, Masayuki Yasugi, Katsuyuki Hotta, Nagio Takigawa, Toshiaki Sendo, Mitsune Tanimoto, and Katsuyuki Kiura
- Organizer
  European Society for Medical Oncology
- Place of Presentation
  Madrid, Spain
- Year and Date
  2014-09-26 – 2014-09-30
- Data Source
  KAKENHI-PROJECT-24659404

1. TAKIGAWA Nagio (60325107)

# of Collaborated Projects: 8 results

# of Collaborated Products: 80 results
2. TAKATA Minoru (30281728)

# of Collaborated Projects: 8 results

# of Collaborated Products: 7 results
3. Ohashi Kadoaki (60729193)

# of Collaborated Projects: 8 results

# of Collaborated Products: 61 results
4. HARADA Mine (00019621)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
5. TABATA Masahiro (30243504)

# of Collaborated Projects: 5 results

# of Collaborated Products: 12 results
6. YOSHINO Tadashi (70183704)

# of Collaborated Projects: 5 results

# of Collaborated Products: 3 results
7. ISHIMARU Fumihiko (50284097)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
8. SHINAGAWA Katsuji (00273988)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
9. ICHIHARA Eiki (40549705)

# of Collaborated Projects: 3 results

# of Collaborated Products: 21 results
10. 久保寿夫 (90726928)

# of Collaborated Projects: 3 results

# of Collaborated Products: 27 results
11. UEOKA Hiroshi (40168612)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. TAKENAKA Katsuto (30301295)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. HOTTA Katsuyuki (70379816)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
14. OCHI Nobuaki (80611615)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
15. AOE Motoi (80260660)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
16. 冨田秀太 (10372111)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
17. TANIMOTO Yasushi (60284098)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
18. HIRAKI Takao (50423322)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. GOBARA Hideo (10379745)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. KANAZAWA Susumu (20243511)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. TOYOOKA Shinichi (30397880)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
22. KATO Katsuya (80379742)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. NAKABEPPU Yusaku (30180350)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. NAKAMURA Eizo (80201672)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. YAMANE Hiromichi (50624897)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. TABAYASHI Takayuki (60624898)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. SATO AKIKO (30623532)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
28. KONDO Eisei (30379747)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
29. MATSUSHITA Nobuko (30333222)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. KITAO Hiroyuki (30368617)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. HIRANO Seiki (20368616)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. 武田俊一 (60188191)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. 八木孝司 (80182301)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. 下田和哉 (90311844)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. 権藤久司 (10253428)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
36. 池田和真 (50176088)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
37. 三村秀文 (10304362)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
38. 伊藤隆明 (70168392)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
39. 山本和彦 (40333223)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
40. 公文裕巳 (30144760)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
41. 片山量平 (60435542)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
42. SHIGEKI Umemura

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
43. TAKUMI Kishimoto

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
44. KUDO Kenichiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
45. Kato Yuka

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
46. Tamura Tomoki

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
47. Ninomiya Kiichiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
48. Yoshida Tadashi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
49. HIGO Hisao

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
50. 頼冠明

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
51. 高田三郎

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
52. 大澤昌宏

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
53. 武田洋昌

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
54. 藤井昌学

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
55. 柏原宏美

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
56. 原田大二郎

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
57. 八杉昌幸

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
58. TAKIGUCHI Yuuichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
59. Makimoto Go

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
60. 鵜殿平一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
61. 阪口政清

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
62. 土岐祐一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
63. 西川博嘉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
64. 大谷理浩

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
65. 藤田直子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KIURA Katuyuki 木浦 勝行

Research Projects

Research Products

Co-Researchers

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of innovative immunotherapy for lung cancer using tumor immune-activating gene REICPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Comprehensive analysis of druggable tyrosine kinase in idiopathic interstitial pneumoniaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Next generation lung cancer mice model for conquering cancer stemPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Basic study on combined modality therapy for advanced lung cancer harboring activated EGFR gene mutationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Basic and clinical study of EGFR gene mutation-positive lung cancer using a genetically modified mousePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A basic studyon malignant mesothelioma pathogenesis by internal radiation exposure of radium contained in the iron-containing proteinPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

KIURA Katuyuki 木浦勝行