Ohta Tsutomu 太田力

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OHTA Tsutomu 太田力

太田力オオタツトム

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Researcher Number	10290892
External Links
Affiliation (Current)	2025: 常葉大学, 保健医療学部, 教授
Affiliation (based on the past Project Information) *help	2021 – 2024: 常葉大学, 保健医療学部, 教授 2013 – 2014: 独立行政法人国立がん研究センター, 研究所, ユニット長 2010 – 2011: 独立行政法人国立がん研究センター, 研究所, ユニット長 2009: National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East, 腫瘍ゲノム解析情報研究部, 室長 2005 – 2007: 国立がんセンター研究所, 疾病ゲノムセンター, 室長 … More 2004: National Cancer Center Research Institute, Genetic-Division, Section-Head, 腫瘍ゲノム解析情報研究部, 室長 2004: 国立がんセンター研究所, 腫瘍ゲノム解析情報研究部, 室長 2003: 国立がんセンター, 研究所・腫瘍ゲノム解析情報研究部, 室長 2002: 国立ガンセンター研究所, 腫瘍ゲノム解析・情報研究部, 室長 1999: 遺伝研, 助手 1997 – 1999: 国立遺伝学研究所, 細胞遺伝研究系, 助手 1998: 国立遺伝学研究所, 細胞遺伝研究系 Less
Review Section/Research Field	Principal Investigator Basic Section 59010:Rehabilitation science-related / Molecular biology / Molecular biology / Biological Sciences / Biological Sciences Except Principal Investigator Biological Sciences / Molecular biology / Biological Sciences
Keywords	Principal Investigator 出芽酵母 / DNA複製時エラーの除去 / DNA傷害の修復 / 減数分裂期組換え / 転写 / 抗がん剤 / NBS1 / SWI蛋白質複合体 / クロマチン構造 / 遺伝的組換え … More / クロマチン / 骨転移 / 滑膜肉腫 / DNA Chip / Mre11 / RAD50 / 乳児白血病 / 電離放射線 / DNAチップ / MRE11 / 転写因子 / 癌細胞 / 細胞増殖 / DNAチップ解析 / インテグレース / ヒトAIDSウイルス / 核マトリックス / 遺伝子組換え / SWIタンパク / 組換え / Mre11タンパク … More Except Principal Investigator Mre11 / クロマチン / No need of Xrs2 in DNA damage repair / Roles of rad52 in recombination / recombination specific helicase MER3 / Tell-Mre11 checkpoint pathway / Domain structure of Xrs2 / DNA homology search by Rad51・Rad52 / Xrs2 complex / Rad5O / melotic recombination / Mre11 DNA結合活性 / RAD51の転写制御 / Mre11,Rad50,Xrs2蛋白質 / DNA二重連鎖切断の修復 / 減数分裂期組換 / Mer3の交叉型組換えと染色体分配の役割 / Mer3蛋白質 / Mre11のリン酸化の役割 / テロメアG-rich構造を認識するMre11 / DNA傷害修復でのMre11の役割 / Mre11蛋白質の機能制御 / Tell-Mrellチェックポイント経路 / Mrell-Rad50-Xrs2複合体 / テロメアG鎖の二次構造認識 / DNA複製フォークの再生 / DNA二重鎖切断修復 / テロメア長維持 / Xrs2の機能ドメイン / Rad51蛋白質 / Xrs20複合体foci / Sae2のドメイン構造 / 組換えDNA修復合成 / Xrs2のMre11結合領域 / 制限酵素SceI / Xrs2はDNA修復にいらない / Rad52の組換えにおける役割 / 組換え特異的ヘリカーゼMer3 / Tel1-Mre11チェックポイント経路 / Xrs2のドメイン構造 / Rad51・Rad52が相同性を検索 / Xrs2複合体 / Rad50 / 減数分裂期組換え / 発現制御 / 転写因子 / Bach2 / Bach1 / hOGG1 / XRCC1 / CYP2E1 / GSTM1 / 肝吸虫感染 / 肝内胆管がん / 肝臓がん / 胆道がん / 個体発生 / クロヌチン / 基本転写因子 / 転写 / 組換え遺伝子 / テロメア / ヌクレアーゼ活性 / MRE11 / 組換え Less

骨転移患者のリハビリテーションに応用できる薬剤の探索Principal Investigator
- Principal Investigator
  
  太田力
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59010:Rehabilitation science-related
- Research Institution
  Tokoha University
Search for drugs that improve limb function after synovial sarcoma using the characteristics of tumor cellsPrincipal Investigator
- Principal Investigator
  
  OHTA Tsutomu
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59010:Rehabilitation science-related
- Research Institution
  Tokoha University
癌細胞における転写サイクルの強制回転の解析Principal Investigator
- Principal Investigator
  
  太田力
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  National Cancer Center Japan
Search for New Cancer Cell Growth PathwayPrincipal Investigator
- Principal Investigator
  
  OHTA Tsutomu
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Molecular biology
- Research Institution
  National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
Comparative Analysis of the DECODE Systems in Hematopoiesis and Oxidative Stress Response
- Principal Investigator
  
  IGARASHI Kazuhiko
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
タイ寄生虫感染関連胆道がんの症例・対照研究による遺伝子多型の解析
- Principal Investigator
  
  三輪正直
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  University of Tsukuba
Analysis for New Cell Cycle RegulationPrincipal Investigator
- Principal Investigator
  
  OHTA Tsutomu
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Molecular biology
- Research Institution
  National Cancer Center Research Institute
転写制御複合体形成のダイナミクスとその生物機能の解明
- Principal Investigator
  
  山本雅之
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Molecular biology
- Research Institution
  University of Tsukuba
クロマチン構造を介した転写調節機構の解明Principal Investigator
- Principal Investigator
  
  太田力
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  National Institute of Genetics
Molecular mechanisms of generation of pleiotropic effects of recombination genes
- Principal Investigator
  
  OGAWA Tomoko
- Project Period (FY)
  1999 – 2003
- Research Category
  
  Grant-in-Aid for Specially Promoted Research
- Review Section
  
  Biological Sciences
- Research Institution
  Iwate College of Nursing
  National Institute of Genetics
減数分裂期組換えの機能解析Principal Investigator
- Principal Investigator
  
  太田力
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Molecular biology
- Research Institution
  National Institute of Genetics
クロマチン構造を介した組換え反応の機能解析Principal Investigator
- Principal Investigator
  
  太田力
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  National Institute of Genetics
クロマチン構造を介した転写調節機構の解明Principal Investigator
- Principal Investigator
  
  太田力
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  National Institute of Genetics
ヒトHIV・インテグレース補助する宿主核内因子SWI蛋白質の機能解析Principal Investigator
- Principal Investigator
  
  太田力
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  National Institute of Genetics
組換え蛋白質複合体の精製と機能解析Principal Investigator
- Principal Investigator
  
  太田力
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Molecular biology
- Research Institution
  National Institute of Genetics
組換えに関する染色体構造の機能解析
- Principal Investigator
  
  田中茂生
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Molecular biology
- Research Institution
  National Institute of Genetics
クロマチン構造を介した組換え反応の機能解析Principal Investigator
- Principal Investigator
  
  太田力
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  National Institute of Genetics
クロマチン構造変化を介した転写調節機構の解明Principal Investigator
- Principal Investigator
  
  太田力
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  National Institute of Genetics

All 2024 2023 2011 2010 2009 2008

All Journal Article Presentation

[Journal Article] High Expression of Fas-Associated Factor 1 Indicates a Poor Prognosis in Non-Small-Cell Lung Cancer2023
- Author(s)
  Hu De、Yamada Hidetaka、Yoshimura Katsuhiro、Ohta Tsutomu、Tsuchiya Kazuo、Inoue Yusuke、Funai Kazuhito、Suda Takafumi、Iwashita Yuji、Watanabe Takuya、Ogawa Hiroshi、Kurono Nobuhito、Shinmura Kazuya、Sugimura Haruhiko
- Journal Title
  
  Current Oncology
  
  Volume: 30 Issue: 11 Pages: 9484-9500
- DOI
  10.3390/curroncol30110687
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K11252
[Journal Article] Up-regulation of PSF1 Promotes the Growth of Breast Cancer Cells2010
- Author(s)
  Nakahara I, Miyamoto M, Shibata T, Akashi-Tanaka S, Mogushi K, Oda K, Ueno M, Takakura N, Mizushima H, Tanaka H, and Ohta T
- Journal Title
  
  Genes Cells
  
  Volume: 15 Issue: 10 Pages: 1015-1024
- DOI
  10.1111/j.1365-2443.2010.01442.x
- Data Source
  KAKENHI-PROJECT-21570191
[Journal Article] Bach1 inhibits oxidative stress-induced cellular senescence by impeding p53 function on chromatin.2008
- Author(s)
  Dohi, Y., Ikura, T., Hoshikawa, Y., Katoh, Y., Ota, K., Nakanome, A., Muto, A., Omura, S., Ohta, T., Ito, A., Yoshida, M., Noda, T., Igarashi, K
- Journal Title
  
  Nature Struct. Mol. Biol 15
  
  Pages: 1246-1254
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17054028
[Presentation] FAF1の高発現は非小細胞肺癌の予後不良を示す2024
- Author(s)
  山田英孝, 胡徳, 吉村克洋, 太田力, 井上裕介, 船井和仁, 渡邊拓弥, 小川博, 椙村春彦, 新村和也
- Organizer
  第113回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-21K11252
[Presentation] Development of treatments for CIC-rearranged sarcomas: Multiplex kinase activity analysis and drug screening using patient-derived cancer models2023
- Author(s)
  Osaki J, Noguchi R, Ono T, Adachi Y, Yanagihara K, Yoshimatsu Y, Ohta T, Kondo T
- Organizer
  日本プロテオーム学会 2023年大会
- Data Source
  KAKENHI-PROJECT-21K11252
[Presentation] Molecular Analysis of Synovial Sarcoma(滑膜肉腫発症機構の解明)2011
- Author(s)
  大野(宮本)麻美子、太田力
- Organizer
  第70回日本癌学会学術総
- Place of Presentation
  名古屋
- Year and Date
  2011-09-03
- Data Source
  KAKENHI-PROJECT-21570191
[Presentation] 網羅的遺伝子発現解析を用いた抗がん剤抵抗性機構の解明2010
- Author(s)
  太田力
- Organizer
  第33回日本分子生物学会年会、第83回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-14
- Data Source
  KAKENHI-PROJECT-21570191
[Presentation] Constitutive activation of Nrf2 provides advantages for lung cancer cell growth2010
- Author(s)
  宮本麻美子、太田力
- Organizer
  第69回日本癌学会学術総
- Place of Presentation
  大阪
- Year and Date
  2010-09-07
- Data Source
  KAKENHI-PROJECT-21570191
[Presentation] Double-edged Sword of the Nrf2-Keap1 stress Response System : Carcinogenesis and Cancer Chemoprevention2009
- Author(s)
  山本雅之、柴田龍弘、太田力、Kit Tong,黒河博文、鈴木貴史、田口恵子、本橋ほずみ
- Organizer
  第68回日本癌学会学術総
- Place of Presentation
  横浜
- Year and Date
  2009-09-09
- Data Source
  KAKENHI-PROJECT-21570191
[Presentation] Comprehensive analysis of new therapeutic targeting gene in Breast Cancer2009
- Author(s)
  中原泉,柴田龍弘,鈴木華絵,水島洋,上野将也,高倉伸幸,田中博,太田力
- Organizer
  第68回日本癌学会学術総
- Place of Presentation
  横浜
- Year and Date
  2009-09-08
- Data Source
  KAKENHI-PROJECT-21570191

1. OGAWA Tomoko (80028208)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. 田中茂生 (10281586)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. IGARASHI Kazuhiko (00250738)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. MUTO Akihiko (80343292)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. SHINOHARA Akira (00252578)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. TSUKAMOTO Yasumasa (80341725)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. OGAWA Hideyuki (70028207)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. SHINOHARA Miki (80335687)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 山本雅之 (50166823)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 深水昭吉 (60199172)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 田中俊之 (10217052)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 本橋ほづみ (00282351)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 青田聖恵 (80289363)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 三輪正直 (20012750)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 内田和彦 (90211078)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 轟健 (70114105)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 花井修次 (80333483)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. THOMA Fritz

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. CEDAR Howard

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. LICHTEN Mich

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 本荘哲

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Ohta Tsutomu 太田 力

OHTA Tsutomu 太田 力

太田 力 オオタ ツトム

Research Projects

Research Products

Co-Researchers

骨転移患者のリハビリテーションに応用できる薬剤の探索Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Search for drugs that improve limb function after synovial sarcoma using the characteristics of tumor cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

癌細胞における転写サイクルの強制回転の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Search for New Cancer Cell Growth PathwayPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Comparative Analysis of the DECODE Systems in Hematopoiesis and Oxidative Stress Response

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

タイ寄生虫感染関連胆道がんの症例・対照研究による遺伝子多型の解析

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis for New Cell Cycle RegulationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

転写制御複合体形成のダイナミクスとその生物機能の解明

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

クロマチン構造を介した転写調節機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Molecular mechanisms of generation of pleiotropic effects of recombination genes

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

減数分裂期組換えの機能解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

クロマチン構造を介した組換え反応の機能解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

クロマチン構造を介した転写調節機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Ohta Tsutomu 太田力

OHTA Tsutomu 太田力

太田力オオタツトム