Cabral Horacio ＣａｂｒａｌＨｏｒａｃｉｏ

… Alternative Names

CABRAL Horacio CABRAL Horacio

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Researcher Number	10533911
Other IDs	https://orcid.org/0000-0002-4030-2631
Affiliation (Current)	2024: 東京大学, 大学院工学系研究科(工学部), 准教授 2024: 公益財団法人川崎市産業振興財団(ナノ医療イノベーションセンター), ナノ医療イノベーションセンター, 客員研究員
Affiliation (based on the past Project Information) *help	2015 – 2024: 東京大学, 大学院工学系研究科(工学部), 准教授 2018: 東京大学, 工学部, 准教授 2017: 東京大学, 医学(系)研究科(研究院), その他 2016: 東京大学, 大学院工学系研究科, 准教授 2014: 東京大学, 工学(系)研究科(研究院), 准教授 2011 – 2013: 東京大学, 工学(系)研究科(研究院), 講師 2012: 東京大学, 大学院・工学系研究科, 講師
Review Section/Research Field	Principal Investigator Medium-sized Section 90:Biomedical engineering and related fields / Biomedical engineering/Biomaterial science and engineering / Basic Section 90110:Biomedical engineering-related / Biomedical engineering/Biomaterial science and engineering / Medium-sized Section 54:Internal medicine of the bio-information integration and related fields / Basic Section 90120:Biomaterials-related / Biomedical engineering/Biological material science Except Principal Investigator Medium-sized Section 90:Biomedical engineering and related fields / Biomedical engineering/Biomaterial science and engineering / Basic Section 90120:Biomaterials-related … More / Basic Section 90110:Biomedical engineering-related / Basic Section 50010:Tumor biology-related / Basic Section 56010:Neurosurgery-related / Medium-sized Section 50:Oncology and related fields / Digestive surgery / Obstetrics and gynecology / Cardiovascular surgery Less
Keywords	Principal Investigator Polymeric micelles / Nanomedicine / mRNA / Cancer / immunotherapy / nanomedicine / in vivo CAR T / 高分子ミセル / ドラッグデリバリー / Liposomes … More / Dexamethasone / Breast cancer / Lung metastasis / Tumor stffness / Tumor normalization / Tumor microenvironment / Cas9 / polymeric micelles / Endosome escape / Cathepsin B / KRAS / Gene editing / Fibroblasts / Tranilast / Antibody ligands / Polymeric nanocarriers / Immunotherapy / Tumor microenvironments / CAFs / autoimmune disease / ナノメディシン / アプタマー / polymeric nanocarrier / hybridization / protein translatiokn / theophylline / triggered translation / theophyline / polymer / aptamer / cancer / Antibody fragment / CAR T cells / ナノデバイス / ナノバイオ / Anticancer drugs / マクロファージ標的 / 抗炎症治療 / 抗癌治療 / 胎盤輸送 / 高分子ナノメディシン / Star-shaped polymers / Preeclampsia / Preterm birth / Size effect / Placental barrier / Pre-eclampsia / Pre-term birth / Size control / Placenta / 制がん剤 / 腫瘍ターゲティング / グリオーマ / アクティブターゲティング / ナノ粒子のサイズ / 環状RGDペプチド / オキサリプラチン / 高分子型ミセル / リンパ節転移 … More Except Principal Investigator 高分子ミセル / ドラッグデリバリーシステム / 免疫チェックポイント阻害剤 / がん免疫療法 / 癌 / ドラッグデリバリー / がん治療 / 血液脳腫瘍関門 / DDS / 病理 / ナノ粒子 / 造影剤 / マンガン / MRI / 免疫チェックポイント阻害療法 / 細胞内抗体送達システム / 細胞内免疫チェックポイント / 高分子修飾抗体 / 細胞内抗体デリバリー / 炎症抑制 / 標的化 / 肺線維症 / 核酸医薬 / 抗PD-1抗体 / エピルビシンミセル / 併用 / HYAL / MMP / 膵臓癌 / 腫瘍間質 / 耐性克服 / がん間質 / 膵臓がん / ナノ治療薬 / 化学療法 / 白金制がん剤 / ビタミンC / 酸化還元反応 / 金属錯体 / がんの標的治療 / EPR効果 / 近赤外線 / 腫瘍蛍光 / 転移性脳腫瘍 / ドラックデリバリーシステム / 術中蛍光造影 / インドシアニングリーン / 脳脊髄腫瘍 / 走化性制御 / mRNA療法 / 細胞傷害性リンパ球 / マンガン造影剤 / 抗体 / 膠芽腫 / mRNA / 肝細胞癌 / Gd-DTPA / Drug delivery system / polymer / drug delivery system / 蛍光色素 / MRI造影剤 / 放射線 / バイオテクノロジー / 妊娠 / 妊婦 / 胎盤 / リガンド分子 / 還元環境応答性 / タンパク質デリバリー / 脳腫瘍 / 超分子 / ナノ材料 / 超分子化学 / 生体イメージング / 高解像イメージング / Mn / ナノDDS / 定量 / 病理診断 Less

Development of a Targeted Therapeutic Approach for Idiopathic Pulmonary Fibrosis Using a Drug Delivery System Loaded with Ligand-Nucleic Acid Pharmaceuticals
- Principal Investigator
  
  喜納宏昭
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 90110:Biomedical engineering-related
- Research Institution
  Kawasaki Institute of Industrial Promotion Innovation Center of NanoMedicine
難治性KRAS駆動型膵臓がんに対する革新的な遺伝子編集治療法の開発Principal Investigator
- Principal Investigator
  
  Cabral Horacio
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Review Section
  
  Basic Section 90110:Biomedical engineering-related
- Research Institution
  The University of Tokyo
Development of Innovative Cancer Genome Editing Therapy Using Polymeric Micelles Implementing High Precision Intracellular Delivery FunctionPrincipal Investigator
- Principal Investigator
  
  Cabral Horacio
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  The University of Tokyo
mRNA therapy for the treatment of autoimmune diseases that produces chimeric antigen receptor regulatory T cells in vivoPrincipal Investigator
- Principal Investigator
  
  Cabral Horacio
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 54:Internal medicine of the bio-information integration and related fields
- Research Institution
  The University of Tokyo
Development of intracellular antibody delivery systems for intracellular immune checkpoint blockade therapy
- Principal Investigator
  
  持田祐希
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 90120:Biomaterials-related
- Research Institution
  Kawasaki Institute of Industrial Promotion Innovation Center of NanoMedicine
低侵襲性の反応性ナノ・マンガン造影剤開発による「MRI病理組織変性解析法」の創成
- Principal Investigator
  
  青木伊知男
- Project Period (FY)
  2021 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  National Institutes for Quantum Science and Technology
Cancer immunotherapy with mRNA-loaded polymeric micelles for in situ creation of tumor-infiltrating killer cells
- Principal Investigator
  
  片岡一則
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  Kawasaki Institute of Industrial Promotion Innovation Center of NanoMedicine
インドシアニングリーンを用いた脳脊髄腫瘍の術中蛍光診断の確立と治療技術の開発
- Principal Investigator
  
  武藤淳
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Fujita Health University
Development of nano-therapeutic agents to overcome immune checkpoint inhibitor resistance due to tumor stroma of intractable cancer
- Principal Investigator
  
  喜納宏昭
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Kawasaki Institute of Industrial Promotion Innovation Center of NanoMedicine
Development of nanotherapeutic agents that boost immunotherapy by precision targeting of cancer-related fibroblastsPrincipal Investigator
- Principal Investigator
  
  Cabral Horacio
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  The University of Tokyo
Cancer immunotherapy by in vivo generation of CAR T cells based on targeted mRNA deliveryPrincipal Investigator
- Principal Investigator
  
  Cabral Horacio
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 90120:Biomaterials-related
- Research Institution
  The University of Tokyo
Development of brain tumor-penetrant protein delivery system realizing immunotherapy of malignant brain tumor
- Principal Investigator
  
  Kataoka Kazunori
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  Kawasaki Institute of Industrial Promotion Innovation Center of NanoMedicine
Pioneering glioblastoma therapy by in situ mRNA-based amplification of immune checkpoint inhibitors
- Principal Investigator
  
  Kataoka Kazunori
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 50:Oncology and related fields
- Research Institution
  Kawasaki Institute of Industrial Promotion Innovation Center of NanoMedicine
Development of mRNA drug with RNA type aptamer conferring cell type specific translation activation functionPrincipal Investigator
- Principal Investigator
  
  Cabral Horacio
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  The University of Tokyo
Manganese Staining-MRI Pathological Analysis
- Principal Investigator
  
  Aoki Ichio
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  National Institutes for Quantum Science and Technology
Development of a nano-pharmaceutical strategy for safely and effectively treating pregnant cancer patientsPrincipal Investigator
- Principal Investigator
  
  Cabral Horacio
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  The University of Tokyo
Development of novel supramolecular drug for the treatments of neointimal lesions and aortic aneurysm
- Principal Investigator
  
  Miura Yutaka
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cardiovascular surgery
- Research Institution
  The University of Tokyo
Development of therapeutic method by MR fluorescence image by Gd-DTPA-fluorescent dye loading polymeric micelle
- Principal Investigator
  
  Kaida Sachiko
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Shiga University of Medical Science
Overcoming physical barriers arising in the drug delivery of nanomedicines to lung metastasesPrincipal Investigator
- Principal Investigator
  
  Cabral Horacio
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  The University of Tokyo
Evaluation of placental transport of drug-loaded polymeric micelles
- Principal Investigator
  
  MIZUNO KAZUE
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  The University of Tokyo
Development of super-selective cancer therapy by utilizing vitamin C-activatable oxidized polymeric micelles
- Principal Investigator
  
  Mochida Yuki
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  Kawasaki Institute of Industrial Promotion Innovation Center of NanoMedicine
Effect of the size of ligand-conjugated nanocarriers on their accumulation and therapeutic effect in solid tumorsPrincipal Investigator
- Principal Investigator
  
  CABRAL Horacio
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  The University of Tokyo
Targeting ability of systemically administered drug-loaded polymeric micelles against lymph node metastasisPrincipal Investigator
- Principal Investigator
  
  CABRAL Horacio
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  The University of Tokyo

All 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 Other

All Journal Article Presentation Patent

[Journal Article] Nanomedicine for brain cancer2022
- Author(s)
  Quader Sabina、Kataoka Kazunori、Cabral Horacio
- Journal Title
  
  Advanced Drug Delivery Reviews
  
  Volume: 182 Pages: 114115-114115
- DOI
  10.1016/j.addr.2022.114115
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21KK0197
[Journal Article] Mechanically interlocked molecular architectures of valinomycin as cancer targeted prodrugs2022
- Author(s)
  Tachihara Yoshihiro、Nakagawa Yasuhiro、Miyazaki Takuya、Anraku Yasutaka、Cabral Horacio
- Journal Title
  
  Nano Select
  
  Volume: - Issue: 8 Pages: 1242-1251
- DOI
  10.1002/nano.202100368
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K19045, KAKENHI-PROJECT-21K18064, KAKENHI-PROJECT-21KK0197
[Journal Article] Conjugation of glucosylated polymer chains to checkpoint blockade antibodies augments their efficacy and specificity for glioblastoma2021
- Author(s)
  T. Yang X. Liu, H. Zhou, J. Xie, Y. Mochida, H. Kinoh, H. Cabral, K Kataoka
- Journal Title
  
  Nature Biomedical Engineering
  
  Volume: 5 Issue: 11 Pages: 1274-1287
- DOI
  10.1038/s41551-021-00803-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H02774
[Journal Article] Nanomedicines blocking adaptive signals in cancer cells overcome tumor TKI resistance.2020
- Author(s)
  H. Kinoh, H. Shibasaki, X. Liu, T. Yamasoba, H. Cabral, K. Kataoka
- Journal Title
  
  J. Control. Release
  
  Volume: 321 Pages: 132-144
- DOI
  10.1016/j.jconrel.2020.02.008
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03179, KAKENHI-PROJECT-17K07234, KAKENHI-PROJECT-18K19901
[Journal Article] Enhanced MRI‐Guided Gadolinium (III) Neutron Capture Therapy by Polymeric Nanocarriers Promoting Tumor Accumulation and Intracellular Delivery2020
- Author(s)
  Qin Changyuan、Hou Xuan、Khan Thahomina、Nitta Nobuhiro、Yanagawa Masashi、Sakurai Yuriko、Suzuki Minoru、Masunaga Shin‐Ichiro、Tanaka Hiroki、Sakurai Yoshinori、Takahashi Hiroyuki、Aoki Ichio、Yanagie Hironobu、Cabral Horacio
- Journal Title
  
  ChemNanoMat
  
  Volume: 6 Issue: 3 Pages: 412-419
- DOI
  10.1002/cnma.201900730
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K15995, KAKENHI-PROJECT-16H03179, KAKENHI-PROJECT-18K19901, KAKENHI-PROJECT-19K08171
[Journal Article] Bundling mRNA strands to prepare nano-assemblies with enhanced stability towards RNase for in vivo delivery.2019
- Author(s)
  N. Yoshinaga, E. Cho, K. Koji, Y. Mochida, M. Naito, K. Osada, K. Kataoka, H. Cabral, S. Uchida
- Journal Title
  
  Angew. Chem. Int. Ed.
  
  Volume: 58 Issue: 33 Pages: 11360-11363
- DOI
  10.1002/anie.201905203
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K20086, KAKENHI-PROJECT-17KK0102, KAKENHI-PROJECT-16H03178, KAKENHI-PROJECT-16H03179, KAKENHI-PROJECT-18H03529, KAKENHI-PROJECT-18K19901
[Journal Article] PEG-OligoRNA Hybridization of mRNA for Developing Sterically Stable Lipid Nanoparticles toward In Vivo Administration2019
- Author(s)
  Kurimoto Shota、Yoshinaga Naoto、Igarashi Kazunori、Matsumoto Yu、Cabral Horacio、Uchida Satoshi
- Journal Title
  
  Molecules
  
  Volume: 24 Issue: 7 Pages: 1303-1303
- DOI
  10.3390/molecules24071303
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03179, KAKENHI-PROJECT-17K20086, KAKENHI-PROJECT-18H03529, KAKENHI-PROJECT-18K19901
[Journal Article] Single-stranded DNA-packaged polyplex micelle as adeno-associated-virus-inspired compact vector to systemically target stroma-rich pancreatic cancer.2019
- Author(s)
  T. A. Tockary, W. Foo, A. Dirisala, Q. Chen, S. Uchida, S. Osawa, Y. Mochida, X. Liu, H. Kinoh, H. Cabral, K. Osada, K. Kataoka
- Journal Title
  
  ACS Nano
  
  Volume: 13 Issue: 11 Pages: 12732-12742
- DOI
  10.1021/acsnano.9b04676
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K20086, KAKENHI-PROJECT-18K18393, KAKENHI-PROJECT-17KK0102, KAKENHI-PROJECT-16H03178, KAKENHI-PROJECT-16H03179, KAKENHI-PROJECT-18H03529, KAKENHI-PROJECT-17K07234, KAKENHI-PROJECT-18K19901
[Journal Article] Polymeric Micelles Loading Proteins through Concurrent Ion Complexation and pH‐Cleavable Covalent Bonding for In Vivo Delivery2019
- Author(s)
  Tao Anqi、Huang George Lo、Igarashi Kazunori、Hong Taehun、Liao Suiyang、Stellacci Francesco、Matsumoto Yu、Yamasoba Tatsuya、Kataoka Kazunori、Cabral Horacio
- Journal Title
  
  Macromolecular Bioscience
  
  Volume: 20 Issue: 1 Pages: 1900161-1900161
- DOI
  10.1002/mabi.201900161
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17KT0048, KAKENHI-PROJECT-19K12799, KAKENHI-PROJECT-16H03179, KAKENHI-PROJECT-18K19901
[Journal Article] Dexamethasone Increases Cisplatin-Loaded Nanocarrier Delivery and Efficacy in Metastatic Breast Cancer by Normalizing the Tumor Microenvironment.2019
- Author(s)
  Martin JD, Panagi M, Wang C, Khan TT, Martin MR, Voutouri C, Toh K, Papageorgis P, Mpekris F, Polydorou C, Ishii G, Takahashi S, Gotohda N, Suzuki T, Wilhelm ME, Melo VA, Quader S, Norimatsu J, Lanning RM, Kojima M, Stuber MD, Stylianopoulos T, Kataoka K, Cabral H.
- Journal Title
  
  ACS Nano.
  
  Volume: 13 Issue: 6 Pages: 6396-6408
- DOI
  10.1021/acsnano.8b07865
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07035, KAKENHI-PROJECT-16H03179, KAKENHI-PROJECT-18K19901
[Journal Article] Induced packaging of mRNA into polyplex micelles by regulated hybridization with a small number of cholesteryl RNA oligonucleotides directed enhanced in vivo transfection.2019
- Author(s)
  N. Yoshinaga, S. Uchida, M. Naito, K. Osada, H. Cabral, K. Kataoka
- Journal Title
  
  Biomaterials
  
  Volume: 197 Pages: 255-267
- DOI
  10.1016/j.biomaterials.2019.01.023
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K20086, KAKENHI-PROJECT-17KK0102, KAKENHI-PROJECT-16H03178, KAKENHI-PROJECT-16H03179, KAKENHI-PROJECT-18H03529, KAKENHI-PROJECT-18K19901, KAKENHI-PROJECT-20K20386, KAKENHI-PROJECT-18J14336
[Journal Article] Glucose transporter 1-mediated vascular translocation of nanomedicines enhances accumulation and efficacy in solid tumors2019
- Author(s)
  Suzuki Kazumi、Miura Yutaka、Mochida Yuki、Miyazaki Takuya、Toh Kazuko、Anraku Yasutaka、Melo Vinicio、Liu Xueying、Ishii Takehiko、Nagano Osamu、Saya Hideyuki、Cabral Horacio、Kataoka Kazunori
- Journal Title
  
  Journal of Controlled Release
  
  Volume: 301 Pages: 28-41
- DOI
  10.1016/j.jconrel.2019.02.021
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03179, KAKENHI-PROJECT-16H05422, KAKENHI-PROJECT-17H04742, KAKENHI-PROJECT-17K20094, KAKENHI-PROJECT-18H04170, KAKENHI-PROJECT-20K20386
[Journal Article] Glucose-linked sub-50-nm unimer polyion complex-assembled gold nanoparticles for targeted siRNA delivery to glucose transporter 1-overexpressing breast cancer stem-like cells.2019
- Author(s)
  Y. Yi, H. J. Kim, M. Zheng, P. Mi, M. Naito, B. S. Kim, H. S. Min, K. Hayashi, F. Perche, K. Toh, X. Liu, Y. Mochida, H. Kinoh, H. Cabral, K. Miyata, K. Kataoka
- Journal Title
  
  J. Control. Release
  
  Volume: 295 Pages: 268-277
- DOI
  10.1016/j.jconrel.2019.01.006
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07234, KAKENHI-PROJECT-18K18378, KAKENHI-PROJECT-17H02098, KAKENHI-PROJECT-18H04170, KAKENHI-PROJECT-20K20386, KAKENHI-PROJECT-18K18391
[Journal Article] One-Pot Synthesis of PEG-Poly(amino acid) Block Copolymers Assembling Polymeric Micelles with PEG-Detachable Functionality2019
- Author(s)
  Miyazaki Takuya、Igarashi Kazunori、Matsumoto Yu、Cabral Horacio
- Journal Title
  
  ACS Biomaterials Science & Engineering
  
  Volume: - Issue: 11 Pages: 5727-5733
- DOI
  10.1021/acsbiomaterials.8b01549
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03179, KAKENHI-PROJECT-18K19901, KAKENHI-PROJECT-18H04170
[Journal Article] Targeting ability of self-assembled nanomedicines in rat acute limb ischemia model is affected by size2018
- Author(s)
  Suhara Masamitsu、Miura Yutaka、Cabral Horacio、Akagi Daisuke、Anraku Yasutaka、Kishimura Akihiro、Sano Masaya、Miyazaki Takuya、Nakamura Noriko、Nishiyama Ayako、Kataoka Kazunori、Koyama Hiroyuki、Hoshina Katsuyuki
- Journal Title
  
  Journal of Controlled Release
  
  Volume: 286 Pages: 394-401
- DOI
  10.1016/j.jconrel.2018.07.049
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10748, KAKENHI-PROJECT-16H03179, KAKENHI-PROJECT-16H05422, KAKENHI-PROJECT-17H04742, KAKENHI-PROJECT-16K10652
[Journal Article] Block Copolymer Micelles in Nanomedicine Applications2018
- Author(s)
  Cabral Horacio、Miyata Kanjiro、Osada Kensuke、Kataoka Kazunori
- Journal Title
  
  Chemical Reviews
  
  Volume: 118 Issue: 14 Pages: 6844-6892
- DOI
  10.1021/acs.chemrev.8b00199
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17KK0102, KAKENHI-PROJECT-16H03178, KAKENHI-PROJECT-16H03179, KAKENHI-PROJECT-17H02098, KAKENHI-PROJECT-18H04170, KAKENHI-PROJECT-20K20386
[Journal Article] Robust Polyion Complex Vesicles (PICsomes) under Physiological Conditions Reinforced by Multiple Hydrogen Bond Formation Derived by Guanidinium Groups2018
- Author(s)
  Hori Mao、Cabral Horacio、Toh Kazuko、Kishimura Akihiro、Kataoka Kazunori
- Journal Title
  
  Biomacromolecules
  
  Volume: 19 Issue: 10 Pages: 4113-4121
- DOI
  10.1021/acs.biomac.8b01097
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K20109, KAKENHI-PROJECT-16H03179, KAKENHI-PROJECT-16J10734
[Journal Article] Epirubicin-loaded polymeric micelles effectively treat axillary lymph nodes metastasis of breast cancer through selective accumulation and pH-triggered drug release2018
- Author(s)
  Chida Tsukasa、Miura Yutaka、Cabral Horacio、Nomoto Takahiro、Kataoka Kazunori、Nishiyama Nobuhiro
- Journal Title
  
  Journal of Controlled Release
  
  Volume: 292 Pages: 130-140
- DOI
  10.1016/j.jconrel.2018.10.035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K18383, KAKENHI-PROJECT-18H04163, KAKENHI-PROJECT-16H05422, KAKENHI-PROJECT-16F16058, KAKENHI-PROJECT-16F16407
[Journal Article] Polymeric micelles for targeted tumor therapy of platinum anticancer drugs2017
- Author(s)
  Y. Mochida, H. Cabral, K. Kataoka
- Journal Title
  
  Expert Opin. Drug Deliv.
  
  Volume: -
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K12534
[Journal Article] Molecular cancer imaging with polymeric nanoassemblies: From tumor detection to theranostics.2017
- Author(s)
  P. Mi, F. Wang, N. Nishiyama, H. Cabral
- Journal Title
  
  Macromol. Biosc.
  
  Volume: - Issue: 1
- DOI
  10.1002/mabi.201600305
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03179
[Journal Article] Heterocyclic boronic acids display sialic acid selective binding in a hypoxic tumor relevant acidic environment.2017
- Author(s)
  . Matsumoto, A. J. S.-Brown, T. Khan, T. Miyazawa, H. Cabral, K. Kataoka, Y. Miyahara,
- Journal Title
  
  Chem. Sci.
  
  Volume: 8 Pages: 6165-6170
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03179
[Journal Article] cRGD peptide-installed epirubicin-loaded polymeric micelles for effective targeted therapy against brain tumors2017
- Author(s)
  S. Quader, X. Liu, Y. Chen, P. Mi, T. Chida, T. Ishii, Y. Miura, N. Nishiyama, H. Cabral, K. Kataoka
- Journal Title
  
  J. Control. Release
  
  Volume: 258 Pages: 56-66
- DOI
  10.1016/j.jconrel.2017.04.033
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04635, KAKENHI-PROJECT-16H03179, KAKENHI-PROJECT-16F16058, KAKENHI-PROJECT-16F16407, KAKENHI-PROJECT-16K15104, KAKENHI-PROJECT-16K12904
[Journal Article] Polymeric micelles for targeted tumor therapy of platinum anticancer drugs2017
- Author(s)
  Yuki Mochida, Horacio Cabral, Kazunori Kataoka
- Journal Title
  
  Expert Opinion on Drug Delivery
  
  Volume: - Issue: 12 Pages: 1423-1438
- DOI
  10.1080/17425247.2017.1307338
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03179
[Journal Article] Effective treatment of drug resistant recurrent breast tumors harboring cancer stem-like cells by staurosporine/epirubicin co-loaded polymeric micelles2017
- Author(s)
  J. Zhang, H. Kinoh, L. Hespel, X. Liu, S. Quader, J. Martin, T. Chida, H. Cabral, K. Kataoka,
- Journal Title
  
  Journal of Controlled Release, "Vol. 264, pp. 127-1335, 2017
  
  Volume: 264 Pages: 127-135
- DOI
  10.1016/j.jconrel.2017.08.025
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07234, KAKENHI-PROJECT-16H03179, KAKENHI-PROJECT-16F16731, KAKENHI-PROJECT-16K12904
[Journal Article] cRGD peptide installation on cisplatin-loaded nanomedicines enhances efficacy against locally advanced head and neck squamous cell carcinoma bearing cancer stem-like cells2017
- Author(s)
  Miyano Kazuki、Cabral Horacio、Miura Yutaka、Matsumoto Yu、Mochida Yuki、Kinoh Hiroaki、Iwata Caname、Nagano Osamu、Saya Hideyuki、Nishiyama Nobuhiro、Kataoka Kazunori、Yamasoba Tatsuya
- Journal Title
  
  J Control Release
  
  Volume: 261 Pages: 275-286
- DOI
  10.1016/j.jconrel.2017.06.021
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17KT0048, KAKENHI-PROJECT-16K11226, KAKENHI-PROJECT-17K07234, KAKENHI-PROJECT-17H01401, KAKENHI-PROJECT-15H04635, KAKENHI-PROJECT-16H03179, KAKENHI-PROJECT-16H05422, KAKENHI-PROJECT-17H06641, KAKENHI-PROJECT-16F16058, KAKENHI-PROJECT-16F16407, KAKENHI-PROJECT-16K15104
[Journal Article] Proteasome inhibitor loaded micelles enhance antitumor activity through macrophage reprograming by NF-κB inhibition"2017
- Author(s)
  Hailiang Wu, Anqi Tao, John D. Martin, Sabina Quader, Xueying Liu, Kei Takahashi, Louise Hespel, Yutaka Miura, Yoshihiro Hayakawa, Tatsuro Irimura, Horacio Cabral, Kazunori Kataoka
- Journal Title
  
  J. Pharm. Sci,
  
  Volume: - Issue: 9 Pages: 30217-30224
- DOI
  10.1016/j.xphs.2017.03.031
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03179, KAKENHI-PROJECT-16F16731, KAKENHI-PROJECT-25293011, KAKENHI-PROJECT-16H05422, KAKENHI-PROJECT-26670023, KAKENHI-PROJECT-16K12904
[Journal Article] Polyplex Micelles with Phenylboronate/Gluconamide Cross-Linking in the Core Exerting Promoted Gene Transfection through Spatiotemporal Responsivity to Intracellular pH and ATP Concentration2017
- Author(s)
  Yoshinaga Naoto、Ishii Takehiko、Naito Mitsuru、Endo Taisuke、Uchida Satoshi、Cabral Horacio、Osada Kensuke、Kataoka Kazunori
- Journal Title
  
  Journal of the American Chemical Society
  
  Volume: 139 Issue: 51 Pages: 18567-18575
- DOI
  10.1021/jacs.7b08816
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K20086, KAKENHI-PROJECT-16H03178, KAKENHI-PROJECT-16H03179, KAKENHI-PROJECT-15K20962, KAKENHI-PROJECT-25000006
[Journal Article] Controlled Fab installation onto polymeric micelle nanoparticles for tuned bioactivity2017
- Author(s)
  Chen Shaoyi、Florinas Stelios、Teitgen Abigail、Xu Ze-Qi、Gao Changshou、Wu Herren、Kataoka Kazunori、Cabral Horacio、Christie R. James
- Journal Title
  
  Sci. Technol. Adv. Mater.
  
  Volume: 18 Issue: 1 Pages: 666-680
- DOI
  10.1080/14686996.2017.1370361
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03179
[Journal Article] Block copolymer-boron cluster conjugate for effective boron neutron capture therapy of solid tumors.2017
- Author(s)
  P. Mi, H. Yanagie, N. Dewi, H.-C. Yen, X. Liu, M. Suzuki, Y. Sakurai, K. Ono, H. Takahashi, H. Cabral, K. Kataoka,
- Journal Title
  
  J. Control. Release
  
  Volume: 254 Pages: 1-9
- DOI
  10.1016/j.jconrel.2017.03.036
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03179, KAKENHI-PROJECT-25293267, KAKENHI-PROJECT-15H04635, KAKENHI-PROJECT-16F16058, KAKENHI-PROJECT-16F16407, KAKENHI-PROJECT-16K15104, KAKENHI-PROJECT-15K12534
[Journal Article] Lipid- and polyion complex-based micelles as agonist platforms for TNFR superfamily receptors2016
- Author(s)
  R. N. Gilbreth, S. Novarra, L. Wetzel, S. Florinas, H. Cabral, K. Kataoka, J. RiosDoria, R. J. Christie, M. Baca
- Journal Title
  
  J. Control. Release
  
  Volume: 230 Pages: 104-114
- DOI
  10.1016/j.jconrel.2016.05.041
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03179, KAKENHI-PROJECT-15K12534
[Journal Article] Hydroxychloroquine-conjugated gold nanoparticles for improved siRNA activity2016
- Author(s)
  Federico Perche, Yu Yi, Louise Hespel, Peng Mi, Anjaneyulu Dirisala, Horacio Cabral, Kanjiro Miyata, Kazunori Kataoka
- Journal Title
  
  Biomaterials
  
  Volume: 90 Pages: 62-71
- DOI
  10.1016/j.biomaterials.2016.02.027
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K12534, KAKENHI-PROJECT-14F04352, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-25282141
[Journal Article] Vascular bursts enhance permeability of tumour blood vessels and improve nanoparticle delivery2016
- Author(s)
  Yu Matsumoto, Joseph W. Nichols, Kazuko Toh, Takahiro Nomoto, Horacio Cabral, Yutaka Miura, R. James Christie, Naoki Yamada, Tadayoshi Ogura, Mitsunobu R. Kano, Yasuhiro Matsumura, Nobuhiro Nishiyama, Tatsuya Yamasoba, You Han Bae, Kazunori Kataoka
- Journal Title
  
  Nature Nanotechnology
  
  Volume: - Issue: 6 Pages: 533-538
- DOI
  10.1038/nnano.2015.342
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K12534, KAKENHI-PROJECT-26670738, KAKENHI-PROJECT-26293119, KAKENHI-PROJECT-16H03179, KAKENHI-PROJECT-16K11226
[Journal Article] Nanomedicines eradicating cancer stem-like cells in vivo by pH-triggered intracellular cooperative action of loaded drugs.2016
- Author(s)
  H. Kinoh, Y. Miura, T. Chida, X. Liu, K. Mizuno, S. Fukushima, Y. Morodomi, N. Nishiyama, H. Cabral, K. Kataoka
- Journal Title
  
  ACS Nano
  
  Volume: 10 Issue: 6 Pages: 5643-5655
- DOI
  10.1021/acsnano.6b00900
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03179, KAKENHI-PROJECT-15H04635, KAKENHI-PROJECT-16K15104, KAKENHI-PROJECT-15K12534
[Journal Article] In vivo evaluation of neutron capture therapy effectivity using calcium phosphate-based nanoparticles as Gd-DTPA delivery agent2016
- Author(s)
  Novriana Dewi, Peng Mi, Hironobu Yanagie, Yuriko Sakurai, Yasuyuki Morishita, Masashi Yanagawa, Takayuki Nakagawa, Atsuko Shinohara, Takehisa Matsukawa, Kazuhito Yokoyama, Horacio Cabral, Minoru Suzuki, Yoshinori Sakurai, Hiroki Tanaka, Koji Ono, Nobuhiro Nishiyama, Kazunori Kataoka, Hiroyuki Takahashi
- Journal Title
  
  Journal of Cancer Research and Clinical Oncology
  
  Volume: 142 Issue: 4 Pages: 767-775
- DOI
  10.1007/s00432-015-2085-0
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K12534, KAKENHI-PROJECT-25670571, KAKENHI-PROJECT-25293267
[Journal Article] Enhanced Efficacy against Cervical Carcinomas through Polymeric Micelles Physically Incorporating the Proteasome Inhibitor MG132.2016
- Author(s)
  Matsumoto Y, Miyamoto Y, Cabral H, Matsumoto Y, Nagasaka K, Nakagawa S, Yano T, Maeda D, Oda K, Kawana K, Nishiyama N, Kataoka K, Fujii T
- Journal Title
  
  Cancer Sci
  
  Volume: in press Issue: 6 Pages: 773-781
- DOI
  10.1111/cas.12926
- NAID
  120007089072
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462515, KAKENHI-PROJECT-26670738, KAKENHI-PROJECT-16H03179, KAKENHI-PROJECT-16K11226, KAKENHI-PROJECT-15H04635, KAKENHI-PROJECT-16K15104, KAKENHI-PROJECT-15K12534
[Journal Article] A Nanoparticle platform to evaluate bioconjugation and receptor-mediated cell uptake using crosslinked polyion complex micelles bearing antibody fragments2016
- Author(s)
  Stelios Florinas, Marc Liu, Ryan Fleming, Lilian Van Vlerken-Ysla, Joanne Ayriss, Ryan Gilbreth, Nazzareno Dimasi, Changshou Gao, Herren Wu, Ze-Qi Xu, Shanoyi Chen, Anjaneyulu Dirisala, Kazunori Kataoka, Horacio Cabral, R. James Christie
- Journal Title
  
  Biomacromolecules
  
  Volume: 17 Issue: 5 Pages: 1818-1833
- DOI
  10.1021/acs.biomac.6b00239
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K12534
[Journal Article] A pH-activatable nanoparticle with signal-amplification capabilities for non-invasive imaging of tumour malignancy.2016
- Author(s)
  P. Mi, D. Kokuryo, H. Cabral, H. Wu, Y. Terada, T. Saga, I. Aoki, N. Nishiyama, K. Kataoka,
- Journal Title
  
  Nat. Nanotechnol.
  
  Volume: 11 Issue: 8 Pages: 724-730
- DOI
  10.1038/nnano.2016.72
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03179, KAKENHI-PROJECT-24300167, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-15H04635, KAKENHI-PROJECT-16K15104, KAKENHI-PROJECT-26293295, KAKENHI-PROJECT-15K12534
[Journal Article] Intracellular Delivery of Charge-Converted Monoclonal Antibodies by Combinatorial Design of Block/Homo Polyion Complex Micelles2016
- Author(s)
  Ahram Kim, Yutaka Miura, Takehiko Ishii, Omer F. Mutaf, Nobuhiro Nishiyama, Horacio Cabral, Kazunori Kataoka
- Journal Title
  
  Biomacromolecules
  
  Volume: 17 Issue: 2 Pages: 446-453
- DOI
  10.1021/acs.biomac.5b01335
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K12534, KAKENHI-PROJECT-15H04635, KAKENHI-PROJECT-24689051
[Journal Article] Eradication of CD44-variant positive population in head and neck tumors through controlled intracellular navigation of cisplatin-loaded nanomedicines2016
- Author(s)
  Ming Wang, Yutaka Miura, Kenji Tsuchihashi, Kazuki Miyano, Osamu Nagano, Momoko Yoshikawa, Ami Tanabe, Jun Makino, Yuki Mochida, Nobuhiro Nishiyama, Hideyuki Saya, Horacio Cabral, Kazunori Kataoka
- Journal Title
  
  Journal of Controlled Release
  
  Volume: 230 Pages: 26-33
- DOI
  10.1016/j.jconrel.2016.03.038
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K12534, KAKENHI-PROJECT-26861579, KAKENHI-PROJECT-16K20613
[Journal Article] cRGD-installed polymeric micelles loading platinum anticancer drugs enable cooperative treatment against lymph node metastasis2016
- Author(s)
  Jun Makino, Horacio Cabral, Yutaka Miura, Yu Matsumoto, Ming Wang, Hiroaki Kinoh, Yuki Mochida, Nobuhiro Nishiyama, Kazunori Kataoka
- Journal Title
  
  Journal of Controlled Release
  
  Volume: 220 PartB Pages: 783-791
- DOI
  10.1016/j.jconrel.2015.10.017
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K12534, KAKENHI-PROJECT-15H04635, KAKENHI-PROJECT-26670738, KAKENHI-PROJECT-24689051
[Journal Article] Polymeric Micelle Platform for Multimodal Tomographic Imaging to Detect Scirrhous Gastric Cancer2015
- Author(s)
  Yutaka Miura, Atsushi B. Tsuji, Aya Sugyo, Hitomi Sudo, Ichio Aoki, Masayuki Inubushi, Masakazu Yashiro, Kosei Hirakawa, Horacio Cabral, Nobuhiro Nishiyama, Tsuneo Saga, Kazunori Kataoka
- Journal Title
  
  ACS Biomaterials Science & Engineering
  
  Volume: 1 Issue: 11 Pages: 1067-1076
- DOI
  10.1021/acsbiomaterials.5b00142
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K12534, KAKENHI-PROJECT-24300167, KAKENHI-PROJECT-24689051
[Journal Article] Antibody fragment-conjugated polymeric micelles incorporating platinum drugs for targeted therapy of pancreatic cancer2015
- Author(s)
  J. -Y. Ahn, Y. Miura, N. Yamada, T. Chida, X. Liu, A. Kim, R. Sato, R. Tsumura, Y. Koga, M. Yasunaga, N. Nishiyama, Y. Matsumura, H. Cabral, K. Kataoka
- Journal Title
  
  Biomaterials
  
  Volume: 39 Pages: 23-30
- DOI
  10.1016/j.biomaterials.2014.10.069
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390009, KAKENHI-PROJECT-24659584, KAKENHI-PROJECT-24689051, KAKENHI-PROJECT-25670010, KAKENHI-PROJECT-25750172
[Journal Article] Systemic Targeting of Lymph Node Metastasis through the Blood Vascular System by Using Size-Controlled Nanocarriers2015
- Author(s)
  H. Cabral, J. Makino, Y. Matsumoto, P. Mi, H. Wu, T. Nomoto, K. Toh, N. Yamada, Y. Higuchi, S. Konishi, M.R. Kano, H. Nishihara, Y. Miura, N. Nishiyama, K. Kataoka
- Journal Title
  
  ACS Nano
  
  Volume: Article ASAP Issue: 5 Pages: 4957-67
- DOI
  10.1021/nn5070259
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25750172, KAKENHI-PROJECT-26670738, KAKENHI-PROJECT-24689051
[Journal Article] Progress of drug-loaded polymeric micelles into clinical studies2014
- Author(s)
  H. Cabral, K. Kataoka
- Journal Title
  
  Journal of Controlled Release
  
  Volume: 190 Pages: 465-476
- DOI
  10.1016/j.jconrel.2014.06.042
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25750172
[Journal Article] 22. The impact of "Development of the polymer micelles carrier system for doxorubicin" on the nanomedicine realm: Original Research Article: Development of the polymer micelle carrier system for doxorubicin, 20012014
- Author(s)
  H. Cabral, K. Kataoka
- Journal Title
  
  Journal of Controlled Release
  
  Volume: 190 Pages: 70-72
- DOI
  10.1016/j.jconrel.2014.07.034
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25750172
[Journal Article] Hydrothermally synthesized PEGylated calcium phosphate nanoparticles incorporating Gd-DTPA for contrast enhanced MRI diagnosis of solid tumors2014
- Author(s)
  P. Mi, N. Nishiyama, et al.
- Journal Title
  
  J. Control. Release
  
  Volume: 136 Issue: 1 Pages: 157-163
- DOI
  10.1021/ja406992w
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13F03042, KAKENHI-PROJECT-23685037, KAKENHI-PROJECT-24700476, KAKENHI-PUBLICLY-25107709, KAKENHI-PROJECT-25670010, KAKENHI-PROJECT-25750172
[Journal Article] Multicompartment micelles with adjustable poly (ethylene glycol) shell for efficient in vivo photodynamic therapy2014
- Author(s)
  C. V. Synatschke, N. Nishiyama, et al.
- Journal Title
  
  ACS Nano
  
  Volume: (in press)(印刷中)(掲載確定) Issue: 2 Pages: 1161-1172
- DOI
  10.1021/nn4028294
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13F03042, KAKENHI-PROJECT-23390009, KAKENHI-PROJECT-23790043, KAKENHI-PROJECT-25670010, KAKENHI-PROJECT-25750172, KAKENHI-PROJECT-26670738
[Journal Article] Systemic siRNA delivery to a spontaneous pancreatic tumor model in transgenic mice by PEGylated calcium phosphate hybrid micelles2014
- Author(s)
  F. Pittella, N. Nishiyama, et al.
- Journal Title
  
  J. Control. Release
  
  Volume: 178 Pages: 18-24
- DOI
  10.1016/j.jconrel.2014.01.008
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-13F03042, KAKENHI-PROJECT-23390009, KAKENHI-PROJECT-24659411, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-25282141, KAKENHI-PROJECT-25670010, KAKENHI-PROJECT-25750172
[Journal Article] Polymeric micelles loaded with platinum anticancer drugs target preangiogenic micrometastatic niches associated with inflammation2014
- Author(s)
  H. Wu, H. Cabral, K. Toh, P. Mi, Y.-C. Chen, Y. Matsumoto, N. Yamada, X. Liu, H. Kinoh, Y. Miura, M. R. Kano, H. Nishihara, N. Nishiyama, K. Kataoka
- Journal Title
  
  J. Control. Release
  
  Volume: 189 Pages: 1-10
- DOI
  10.1016/j.jconrel.2014.06.018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13F03042, KAKENHI-PROJECT-23390009, KAKENHI-PROJECT-24659584, KAKENHI-PROJECT-24689051, KAKENHI-PROJECT-25670010, KAKENHI-PROJECT-25750172, KAKENHI-PROJECT-26293119, KAKENHI-PROJECT-26670738
[Journal Article] Hydrothermally synthesized PEGylated calcium phosphate nanoparticles incorporating Gd-DTPA for contrast enhanced MRI diagnosis of solid tumors2014
- Author(s)
  P. Mi, D. Kokuryo, H. Cabral, M. Kumagai, T. Nomoto, I. Aoki, Y. Terada, A. Kishimura, N. Nishiyama, K. Kataoka
- Journal Title
  
  J. Control. Release
  
  Volume: 174 Pages: 63-71
- DOI
  10.1016/j.jconrel.2013.10.038
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13F03042, KAKENHI-PROJECT-23390009, KAKENHI-PUBLICLY-25107709, KAKENHI-PROJECT-25670010, KAKENHI-PROJECT-25750172
[Journal Article] Bundled assembly of helical nanostructures in polymeric micelles loaded with platinum drugs enhancing therapeutic efficiency against pancreatic tumor2014
- Author(s)
  Y. Mochida, H. Cabral, Y. Miura, F. Albertini, S. Fukushima, K. Osada, N. Nishiyama, K. Kataoka
- Journal Title
  
  ACS Nano
  
  Volume: 8 Issue: 7 Pages: 6724-6738
- DOI
  10.1021/nn500498t
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24659584, KAKENHI-PROJECT-24689051, KAKENHI-PROJECT-25670010, KAKENHI-PROJECT-25750172
[Journal Article] Light-induced cytosolic activation of reduction-sensitive camptothecin-loaded polymeric micelles for spatiotemporally controlled in vivo chemotherapy2014
- Author(s)
  H.-C. Yen, H. Cabral, P. Mi, K. Toh, Y. Matsumoto, X. Liu, H. Koori, A. Kim, K. Miyazaki, Y. Miura, N. Nishiyama, K. Kataoka
- Journal Title
  
  ACS Nano
  
  Volume: 8 Issue: 11 Pages: 11591-11602
- DOI
  10.1021/nn504836s
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13F03042, KAKENHI-PROJECT-24659584, KAKENHI-PROJECT-24689051, KAKENHI-PROJECT-25670010, KAKENHI-PROJECT-25750172, KAKENHI-PROJECT-26670738
[Journal Article] siRNA delivery from triblock copolymer micelles with spatially-ordered compartmants of PEG shell, siRNA-loaded intermediate layer, and hydrophobic core2014
- Author(s)
  Hyun Jin Kim, Kanjiro Miyata, Takahiro Nomoto, Meng Zheng, Ahram Kim, Xueying Liu, Horacio Cabral, R. James Christie, Nobuhiro Nishiyama, Kazunori Kataoka
- Journal Title
  
  Biomaterials
  
  Volume: 35 Issue: 15 Pages: 4548-4556
- DOI
  10.1016/j.biomaterials.2014.02.016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13F03349, KAKENHI-PROJECT-23390009, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-25282141, KAKENHI-PROJECT-25670010, KAKENHI-PROJECT-25750172
[Journal Article] Cyclic RGD-linked polymeric micelles for targeted delivery of platinum anticancer drugs to glioblastoma through the blood-brain tumor barrier2013
- Author(s)
  Y. Miura, N. Nishiyama, et al.
- Journal Title
  
  ACS Nano
  
  Volume: 7 Issue: 10 Pages: 8583-8592
- DOI
  10.1021/nn402662d
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13F03042, KAKENHI-PROJECT-23390009, KAKENHI-PROJECT-23790043, KAKENHI-PROJECT-24390340, KAKENHI-PROJECT-24659584, KAKENHI-PROJECT-24689051, KAKENHI-PROJECT-25293273, KAKENHI-PROJECT-25670010, KAKENHI-PROJECT-25750172
[Journal Article] Phenylboronic acid-installed polymeric micelles for targeting sialylated epitopes in solid tumors.2013
- Author(s)
  S. Deshayes, N. Nishiyama, et al.
- Journal Title
  
  J. Am. Chem. Soc.
  
  Volume: 135 Issue: 41 Pages: 15501-15507
- DOI
  10.1021/ja406406h
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13F03042, KAKENHI-PROJECT-23390009, KAKENHI-PROJECT-24659584, KAKENHI-PROJECT-24689051, KAKENHI-PROJECT-25670010, KAKENHI-PROJECT-25750172
[Journal Article] Gd-DTPA-loaded polymer-metal complex micelles with high relaxivity for MR cancer imaging2013
- Author(s)
  P. Mi, H. Cabrala, D. Kokuryo, M. Rafi, Y. Terada, I. Aoki, T. Saga, T. Ishii, N. Nishiyama, K. Kataoka
- Journal Title
  
  Biomaterials
  
  Volume: 34 Issue: 2 Pages: 492-500
- DOI
  10.1016/j.biomaterials.2012.09.030
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390009, KAKENHI-PROJECT-23700526, KAKENHI-PROJECT-25670010
[Journal Article] Polymeric micelles incorporating (1,2-diaminocyclohexane)platinum (II) suppress the growth of orthotopic scirrhous gastric tumors and their lymph node metastasis2012
- Author(s)
  M. Rafi
- Journal Title
  
  J. Control. Release
  
  Volume: 159 Issue: 2 Pages: 189-196
- DOI
  10.1016/j.jconrel.2012.01.038
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390009, KAKENHI-PROJECT-23700526, KAKENHI-PROJECT-23790433
[Journal Article] Evaluation of theDynamics of Drug Delivery Systems (DDS)Using Intravital Real-Time Confocal LaserScanning Microscopy2012
- Author(s)
  Takahiro Nomoto、Yu Matsumoto、KazukoToh、R. James Christie、Kanjiro Miyata、Makoto Oba、Horacio Cabral、Mami Murakami、Shigeto Fukushima、Nobuhiro Nishiyama、Kazunori Kataoka
- Journal Title
  
  Yakugaku Zasshi
  
  Volume: 132巻 Pages: 1347-1354
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23700526
[Journal Article] Evaluation of the Dynamics of Drug Delivery Systems (DDS) Using Intravital Real-Time Confocal Laser Scanning Microscopy2012
- Author(s)
  Takahiro Nomoto, Horacio Cabral, 他9名
- Journal Title
  
  Yakugaku Zasshi
  
  Volume: 132 Pages: 1347-1354
- NAID
  130002489530
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23700526
[Journal Article] Bioactivepolymeric metallosomesself-assembled through blockcopolymer-metal complexation.2012
- Author(s)
  K. Osada, H. Cabral, Y. Mochida, S. -ELee, K. Nagata, T. Matsuura, M.Yamamoto, Y. Anraku, A. Kishimura, N.Nishiyama, K. Kataoka
- Journal Title
  
  J. Am.Chem. Soc.
  
  Volume: 134(32) Issue: 32 Pages: 13172-13175
- DOI
  10.1021/ja304615y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22750098, KAKENHI-PROJECT-23390009, KAKENHI-PROJECT-23685037, KAKENHI-PROJECT-23700526, KAKENHI-PROJECT-24700476
[Patent] 核酸送達用ポリマー化合物2019
- Inventor(s)
  カブラルオラシオ、内田智士、宮崎拓也
- Industrial Property Rights Holder
  東京大学
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Overseas
- Data Source
  KAKENHI-PROJECT-20K20386
[Patent] Drug delivery systems for placenta2019
- Inventor(s)
  Horacio Cabral, Takuya Miyazaki
- Industrial Property Rights Holder
  Horacio Cabral, Takuya Miyazaki
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-16H03179
[Patent] 核酸送達用ポリマー化合物2018
- Inventor(s)
  カブラルオラシオ、　ミヤザキ　タクヤ
- Industrial Property Rights Holder
  カブラルオラシオ、　ミヤザキ　タクヤ
- Industrial Property Rights Type
  特許
- Filing Date
  2018
- Overseas
- Data Source
  KAKENHI-PROJECT-16H03179
[Patent] 酵素反応の測定方法、スクリーニング方法及び測定装置2017
- Inventor(s)
  カブラル　オラシオ、持田祐希、片岡一則
- Industrial Property Rights Holder
  カブラル　オラシオ、持田祐希、片岡一則
- Industrial Property Rights Type
  特許
- Filing Date
  2017
- Acquisition Date
  2017
- Overseas
- Data Source
  KAKENHI-PROJECT-16H03179
[Patent] ポリマー、ポリマーの製造方法、及び薬物複合体2017
- Inventor(s)
  片岡一則、カデールサビーナ、カブラルオラシオ
- Industrial Property Rights Holder
  片岡一則、カデールサビーナ、カブラルオラシオ
- Industrial Property Rights Type
  特許
- Filing Date
  2017
- Acquisition Date
  2017
- Overseas
- Data Source
  KAKENHI-PROJECT-16H03179
[Patent] ポリマー、ポリマーの製造方法、及び薬物複合体2017
- Inventor(s)
  片岡一則、喜納宏昭、カデールサビーナ、カブラルオラシオ
- Industrial Property Rights Holder
  片岡一則、喜納宏昭、カデールサビーナ、カブラルオラシオ
- Industrial Property Rights Type
  特許
- Filing Date
  2017
- Acquisition Date
  2017
- Overseas
- Data Source
  KAKENHI-PROJECT-16H03179
[Patent] ミセル及びその使用2017
- Inventor(s)
  カブラルオラシオ、オヌマ　ユカ
- Industrial Property Rights Holder
  カブラルオラシオ、オヌマ　ユカ
- Industrial Property Rights Type
  特許
- Filing Date
  2017
- Acquisition Date
  2017
- Overseas
- Data Source
  KAKENHI-PROJECT-16H03179
[Patent] 発明の名称：ポリマー、ポリマーの製造方法、及び薬物複合体2016
- Inventor(s)
  片岡一則、Quader 、Cabral Horacio
- Industrial Property Rights Holder
  片岡一則、Quader 、Cabral Horacio
- Industrial Property Rights Type
  特許
- Filing Date
  2016-08-23
- Data Source
  KAKENHI-PROJECT-16H03179
[Patent] 金属とブロック共重合体との錯体を含むミセルを安定化させる方法および安定化されたミセル、並びにミセルからの金属の放出制御法2016
- Inventor(s)
  持田祐希、片岡一則、カブラルオラシオ
- Industrial Property Rights Holder
  持田祐希、片岡一則、カブラルオラシオ
- Industrial Property Rights Type
  特許
- Filing Date
  2016-08-26
- Data Source
  KAKENHI-PROJECT-15K12534
[Patent] ポリマー、ポリマーの製造方法、及び薬物複合体2016
- Inventor(s)
  片岡一則、Quader、Cabral Horacio
- Industrial Property Rights Holder
  片岡一則、Quader、Cabral Horacio
- Industrial Property Rights Type
  特許
- Filing Date
  2016-08-23
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] Stromal disruption of Nanomedicine overcome Immunocheck point inhibitor＆Drug resistance in Stroma-rich pancreatic cancer2022
- Author(s)
  H. Kinoh, H. Cabral, S. Quader, K. Kataoka
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21H02774
[Presentation] Chemo-Immunotherapy of Nanomedicine and anti-PD-1 antibody for Reprogramming Tumor Microenvironment to Overcome anti-PD-1 antibody-Resistance .2022
- Author(s)
  喜納宏昭、カブラルオラシオ、クワドラサビーナ、劉学螢、片岡一則
- Organizer
  7th JCA-AACR Special Joint Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02774
[Presentation] 悪性脳腫瘍（グリオブラストーマ）に対する免疫チェックポイント阻害剤の効果を飛躍的に高めるナノDDSを用いた化学免疫療法2021
- Author(s)
  H. Kinoh, H. Cabral, S. Quader, K. Kataoka
- Organizer
  第80回日本癌学会
- Data Source
  KAKENHI-PROJECT-21H02774
[Presentation] 薬剤送達システムへの応用を指向したホストゲスト相互作用による高分子－環状薬剤複合体の構築2019
- Author(s)
  Y. Tachihara, Y. Nakagawa, Y. Anraku, K. Kataoka, H. Cabral
- Organizer
  Future Trend in Polymer Science 2018,
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] Development of Macrocyclic Drug-Loaded pH-Sensitive Polymeric Micelles by Using Host Guest Interaction2019
- Author(s)
  Y. Tachihara, Y. Nakagawa, Y. Anraku, K. Kataoka, H. Cabral
- Organizer
  TEJIN MIRAI FORUM 2020
- Data Source
  KAKENHI-PROJECT-18K19901
[Presentation] 薬剤送達システムへの応用を指向したホストゲスト相互作用による高分子－環状薬剤複合体の構築2019
- Author(s)
  Y. Tachihara, Y. Nakagawa, Y. Anraku, K. Kataoka, H. Cabral
- Organizer
  Future Trend in Polymer Science 2018,
- Data Source
  KAKENHI-PROJECT-18K19901
[Presentation] Supramolecular Nanomedicines for Targeting Intractable Tumors2019
- Author(s)
  Horacio Cabral
- Organizer
  The University of Tokyo - Karolinska Institute Workshop 2019
- Invited
- Data Source
  KAKENHI-PROJECT-18K19901
[Presentation] nteraction analysis between target membrane proteins and ligand molecules attached to the polymeric micelle with different molecular weight of hydrophilic shell2019
- Author(s)
  N.Nakamura, Y. Anraku, S. Fukushima, K. Tou, H. Cabral, K. Kataoka
- Organizer
  41st Annual Meeting of the Japanese Society for Biomaterials
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19901
[Presentation] Development of novel flexible block catiomers for forming stable polyion complex micelles with mRNA directed to in vivo applications2019
- Author(s)
  W. Yang, T. Miyazaki, S. Uchida, H. Cabral
- Organizer
  2nd G'L'owing Polymer Symposium in Kanto
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] Supramolecular Nanomedicines for Targeting Intractable Tumors2019
- Author(s)
  Horacio Cabral
- Organizer
  The University of Tokyo - Karolinska Institute Workshop 2019
- Invited
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] Development of Macrocyclic Drug-Loaded pH-Sensitive Polymeric Micelles by Using Host Guest Interaction2019
- Author(s)
  Y. Tachihara, Y. Nakagawa, Y. Anraku, K. Kataoka, H. Cabral
- Organizer
  TEJIN MIRAI FORUM 2020
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] Development of polymeric micelles with 5-Boronopicolinic acid ligand to target sialylated epitopes in intratumoral microenvironment"2019
- Author(s)
  T. Khan, K. Igarashi, A. Matsumoto, H. Cabral, K. Kataoka
- Organizer
  32nd International Microprocesses and Nanotechnology Conference (MNC 2019)\
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] Mechanistic analyses of polymer/lipid-based gene transfection processes through membrane integrity assay using proton sensing transistor2019
- Author(s)
  E. Boonstra, H. Hatano, T. Goda, S. Uchida, H. Cabral, Y. Miyahara
- Organizer
  4th International Symposium on Biomedical Engineering, ISBE 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19901
[Presentation] Development of pH-sensitive polymeric micelles effectively utilizing polymer freeze drying by liquid nitrogen2019
- Author(s)
  Y. Tachihara, Y. Nakagawa, Y. Anraku, K. Kataoka, H. Cabral
- Organizer
  10th Research Meeting of Cryogenic Research Center
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] Development of novel flexible block catiomers for forming stable polyion complex micelles with mRNA directed to in vivo applications2019
- Author(s)
  W. Yang, T. Miyazaki, S. Uchida, H. Cabral
- Organizer
  2nd G'L'owing Polymer Symposium in Kanto
- Data Source
  KAKENHI-PROJECT-18K19901
[Presentation] Development of pH-Sensitive Polymeric Micelles for Targeted Delivery of the Macrocycle Valinomycin via Host Guest Interaction2019
- Author(s)
  Y. Tachihara, Y. Nakagawa, Y. Anraku, K. Kataoka, H. Cabral
- Organizer
  68th SPSJ Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19901
[Presentation] Development of polymeric micelles with 5-Boronopicolinic acid ligand to target sialylated epitopes in intratumoral microenvironment"2019
- Author(s)
  T. Khan, K. Igarashi, A. Matsumoto, H. Cabral, K. Kataoka
- Organizer
  32nd International Microprocesses and Nanotechnology Conference (MNC 2019)\
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19901
[Presentation] The Development of Placenta Targeting Simvastatin Nano-Micelle Treatment in PE Mouse Model -Challenge for Clinical Application of Drug Delivery System to Avoid Adverse Effect on Fetus During Pregnancy2019
- Author(s)
  Hiroko Oda, Takeshi Nagamatsu, Yutaka Osuga, Tomoyuki Fujii, Takuya Miyazaki, Horacio Cabral
- Organizer
  Japan Society of Obstetrics and Gynecology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] nteraction analysis between target membrane proteins and ligand molecules attached to the polymeric micelle with different molecular weight of hydrophilic shell2019
- Author(s)
  N.Nakamura, Y. Anraku, S. Fukushima, K. Tou, H. Cabral, K. Kataoka
- Organizer
  41st Annual Meeting of the Japanese Society for Biomaterials
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] Development of pH-Sensitive Polymeric Micelles for Targeted Delivery of the Macrocycle Valinomycin via Host Guest Interaction2019
- Author(s)
  Y. Tachihara, Y. Nakagawa, Y. Anraku, K. Kataoka, H. Cabral
- Organizer
  68th SPSJ Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] Development of pH-sensitive polymeric micelles effectively utilizing polymer freeze drying by liquid nitrogen2019
- Author(s)
  Y. Tachihara, Y. Nakagawa, Y. Anraku, K. Kataoka, H. Cabral
- Organizer
  10th Research Meeting of Cryogenic Research Center
- Data Source
  KAKENHI-PROJECT-18K19901
[Presentation] Mechanistic analyses of polymer/lipid-based gene transfection processes through membrane integrity assay using proton sensing transistor2019
- Author(s)
  E. Boonstra, H. Hatano, T. Goda, S. Uchida, H. Cabral, Y. Miyahara
- Organizer
  4th International Symposium on Biomedical Engineering, ISBE 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] 5-Boronopicolinic acid-installed nano-carriers for targeting sialylated epitopes on cancer cells2018
- Author(s)
  Thahomina Khan, Akira Matsumoto, Horacio Cabral and Kazunori Kataoka
- Organizer
  第34回日本DDS学会
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] Development of 5-boronopicolinic acid-installed polymeric micelles for targeting sialylated epitopes on cancer cels2018
- Author(s)
  K. T. Tareque, A. Matsumoto, H. Cabral, K. Kataoka
- Organizer
  Biomaterials International 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] Analysis of the interaction between target membrane proteins and ligand molecules on polymeric micelles2018
- Author(s)
  N. Nakamura, Y. Anraku, S. Fukushima, K. Toh, H. Cabral, K. Kataoka
- Organizer
  The 12th SPSJ International Polymer Conference (IPC2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H04170
[Presentation] Interaction analysis of ligand molecules on the polymeric micelle penetrating blood-brain barrier2018
- Author(s)
  Noriko Nakamura, Y. Anraku, S. Fukushima, K. Toh, H. Cabral, K. Kataoka
- Organizer
  Biomaterials International 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H04170
[Presentation] Principles of Probe Design for Molecular Imagers2018
- Author(s)
  Horacio Cabral
- Organizer
  Joint Annual Meeting ISMRM-ESMRMB 2018
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] Design of polyplex micelles with phenylboronate ester cross-linking in the core exerting promoted gene transfection through responsivity to intracellular pH and ATP concentration2018
- Author(s)
  N. Yoshinaga, M. Naito, S. Uchida, H. Cabral, K. Osada, K. Kataoka
- Organizer
  256th ACS National Meeting & Exposition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K20386
[Presentation] Real-Time Assessment of Extracellular Vesicles by Intravital Microscopy Imaging2018
- Author(s)
  Horacio Cabral
- Organizer
  10th IFAC Symposium on Biological and Medical Systems
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] グアニジノ基修飾によるmRNA搭載ポリイオンコンプレックスの機能向上2018
- Author(s)
  堀真緒, 吉永直人、内田智士、H. Cabral、片岡一則
- Organizer
  第67回高分子年次大会
- Data Source
  KAKENHI-PROJECT-18K19901
[Presentation] Clinical Challenges towards Next Generation Polymer Therapeutics2018
- Author(s)
  Horacio Cabral
- Organizer
  Controlled Release Society (CRS) Annual Meeting & Exposition 2018
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19901
[Presentation] 血液脳関門突破を指向したDDSキャリアに装着したリガンド分子の標的認識能評価2018
- Author(s)
  中村乃理子、安楽泰孝、福島重人、藤加珠子、H. Cabral、片岡一則
- Organizer
  第67回高分子学会年次大会
- Data Source
  KAKENHI-PROJECT-20K20386
[Presentation] Helical polymer structure provides platinum-loaded polymeric micelles with favorable size and stability for effective tumor-targeting2018
- Author(s)
  Y. Mochida, H. Cabral, Y. Miura, K. Osada, N. Nishiyama, K. Kataoka
- Organizer
  256th ACS National Meeting & Exposition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] Spherical polyplex micelles based on ssDNA packaging and its delivery appeal towards hypopermeable pancreatic tumor2018
- Author(s)
  T.A.Tockary,W. Foo, K. Osada, A. Dirisala, S. Uchida, H. Cabral, X. Liu, K. Kataoka
- Organizer
  第67回高分子年次大会
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] Interaction between target membrane proteins and ligand-decorated polymeric micelles penetrating blood-brain barrier2018
- Author(s)
  N. Nakamura, Y. Anraku, S. Fukushima, K. Toh, H. Cabral, K. Kataoka
- Organizer
  2018 MRS fall meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K20386
[Presentation] Engineering Tumor Microenvironment Toward Enhanced Drug Delivery2018
- Author(s)
  Horacio Cabral
- Organizer
  NanoThailand 2018
- Invited
- Data Source
  KAKENHI-PROJECT-18K19901
[Presentation] Design of polyplex micelles with phenylboronate ester cross-linking in the core exerting promoted gene transfection through responsivity to intracellular pH and ATP concentration2018
- Author(s)
  N. Yoshinaga, M. Naito, S. Uchida, H. Cabral, K. Osada, K. Kataoka
- Organizer
  256th ACS National Meeting & Exposition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19901
[Presentation] Principles of Probe Design for Molecular Imagers2018
- Author(s)
  Horacio Cabral
- Organizer
  Joint Annual Meeting ISMRM-ESMRMB 2018（
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19901
[Presentation] Development of mRNA-loaded nanocarriers based on flexible block ionomers with enhanced affinity for mRNA2018
- Author(s)
  Horacio Cabral
- Organizer
  13th Japan-France DDS Symposium
- Invited
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] コレステロール基修飾短鎖RNAオリゴマーを用いたmRNA内包高分子ミセルの安定化2018
- Author(s)
  吉永直人,内田智士、Cabral Horacio、長田健介、片岡一則
- Organizer
  第67回高分子年次大会
- Data Source
  KAKENHI-PROJECT-18K19901
[Presentation] Analysis of the interaction between target membrane proteins and ligand molecules on polymeric micelles2018
- Author(s)
  N. Nakamura, Y. Anraku, S. Fukushima, K. Toh, H. Cabral, K. Kataoka
- Organizer
  The 12th SPSJ International Polymer Conference (IPC2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K20386
[Presentation] コレステロール基修飾短鎖RNAオリゴマーを用いたmRNA内包高分子ミセルの安定化2018
- Author(s)
  吉永直人,内田智士、Cabral Horacio、長田健介、片岡一則
- Organizer
  第67回高分子年次大会
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] Engineering tumor microenvironment toward enhanced drug delivery2018
- Author(s)
  J. Martin, T. Khan, M. Panagi, T. Stylianopoulos, K. Kataoka, H. Cabral
- Organizer
  The 6th Thailand International Nanotechnology Conference (NanoThailand2018)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K20386
[Presentation] グアニジノ基修飾によるmRNA搭載ポリイオンコンプレックスの機能向上2018
- Author(s)
  堀真緒、吉永直人、内田智士、H. Cabral、片岡一則
- Organizer
  第67回高分子学会年次大会
- Data Source
  KAKENHI-PROJECT-20K20386
[Presentation] Novel pH-sensitive nanomedicine conjugating (+)-JQ-1 homolog inhibits the tumor growth of c-myc high-expressing tumor2018
- Author(s)
  H. Shibasaki, H. Kinoh, S. Quader, X. Liu, H. Cabral, K. Kataoka
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] 少数のコレステロール修飾RNAオリゴマーにより誘起されるmRNA内包高分子ミセルの構造安定化およびマウス肺局所投与への応用2018
- Author(s)
  吉永直人、内田智士、長田健介、位髙啓史、H. Cabral、片岡一則
- Organizer
  第35回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] Clinical Challenges towards Next Generation Polymer Therapeutics2018
- Author(s)
  Horacio Cabral
- Organizer
  Controlled Release Society (CRS) Annual Meeting & Exposition 2018
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] 白金制がん剤内包高分子ミセルの構造および機能を決定するヘリックス形成の重要性2018
- Author(s)
  持田祐希,カブラルオラシオ、片岡一則
- Organizer
  第67回高分子年次大会
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] pH及びグルコースに応答してPEGが脱離する高分子ミセルの構築2018
- Author(s)
  小路恭子、宮崎拓也、持田祐希、L. Hespel、籐加珠子、福島重人、松本有、松元亮、H. Cabral、片岡一則
- Organizer
  第34回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-18H04170
[Presentation] Engineering tumor microenvironment toward enhanced drug delivery2018
- Author(s)
  J. Martin, T. Khan, M. Panagi, T. Stylianopoulos, K. Kataoka, H. Cabral
- Organizer
  The 6th Thailand International Nanotechnology Conference (NanoThailand2018)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H04170
[Presentation] エクソソーム電気泳動解析を高効率化するシアル酸認識高分子の設計と評価2018
- Author(s)
  鹿谷真紀，松元亮，宮原裕二，合田達郎，田畑美幸，カブラルオラシオ，宮崎拓也，一木隆範，赤木貴則，木下ひろみ
- Organizer
  第67回高分子討論会
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] 血液脳関門突破を指向したグルコース修飾高分子ミセルの標的認識能の解析2018
- Author(s)
  中村乃理子、安楽泰孝、福島重人、藤加珠子、H. Cabral、片岡一則
- Organizer
  第67回高分子討論会
- Data Source
  KAKENHI-PROJECT-20K20386
[Presentation] pH及びグルコースに応答してPEGが脱離する高分子ミセルの構築2018
- Author(s)
  小路恭子、宮崎拓也、持田祐希、L. Hespel、籐加珠子、福島重人、松本有、松元亮、H. Cabral、片岡一則
- Organizer
  第35回日本DDS学会学術集会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] Development of 5-boronopicolinic acid-installed polymeric micelles for targeting sialylated epitopes on cancer cells2018
- Author(s)
  T. Khan、H. Cabral、松元亮、片岡一則
- Organizer
  第35回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] Engineering Tumor Microenvironment Toward Enhanced Drug Delivery2018
- Author(s)
  Horacio Cabral
- Organizer
  NanoThailand 2018
- Invited
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] 血液脳関門突破を指向したグルコース修飾高分子ミセルの標的認識能の解析2018
- Author(s)
  中村乃理子、安楽泰孝、福島重人、藤加珠子、H. Cabral、片岡一則
- Organizer
  第67回高分子討論会
- Data Source
  KAKENHI-PROJECT-18H04170
[Presentation] Development of mRNA-loaded nanocarriers based on flexible block ionomers with enhanced affinity for mRNA2018
- Author(s)
  Horacio Cabral
- Organizer
  13th France-Japan DDS Symposium
- Invited
- Data Source
  KAKENHI-PROJECT-18K19901
[Presentation] コレステロール修飾相補鎖RNAを用いたmRNA搭載高分子ミセル安定化2018
- Author(s)
  内田智士、吉永直人、長田健介、位髙啓史、H. Cabral、片岡一則
- Organizer
  第40回日本バイオマテリアル学会大会
- Data Source
  KAKENHI-PROJECT-20K20386
[Presentation] 少数のコレステロール修飾RNAオリゴマーにより誘起されるmRNA内包高分子ミセルの構造安定化およびマウス肺局所投与への応用2018
- Author(s)
  吉永直人、内田智士、長田健介、位髙啓史、H. Cabral、片岡一則
- Organizer
  第35回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-18K19901
[Presentation] グアニジノ基修飾によるmRNA搭載ポリイオンコンプレックスの機能向上2018
- Author(s)
  堀真緒, 吉永直人、内田智士、H. Cabral、片岡一則
- Organizer
  第67回高分子年次大会
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] Interaction analysis of ligand molecules on the polymeric micelle penetrating blood-brain barrier2018
- Author(s)
  Noriko Nakamura, Y. Anraku, S. Fukushima, K. Toh, H. Cabral, K. Kataoka
- Organizer
  Biomaterials International 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K20386
[Presentation] 血液脳関門突破を指向したDDSキャリアに装着したリガンド分子の標的認識能評価2018
- Author(s)
  中村乃理子、安楽泰孝、福島重人、藤加珠子、H. Cabral、片岡一則
- Organizer
  第67回高分子学会年次大会
- Data Source
  KAKENHI-PROJECT-18H04170
[Presentation] Interaction analysis of ligand molecules on the polymeric micelle penetrating blood-brain barrier2018
- Author(s)
  N. Nakamura,Y. Anraku, S. Fukushima, K. Toh, H. Cabral, K. Kataoka
- Organizer
  Biomaterials International 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] Real-Time Assessment of Extracellular Vesicles by Intravital Microscopy Imaging2018
- Author(s)
  Horacio Cabral
- Organizer
  10th IFAC Symposium on Biological and Medical Systems
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19901
[Presentation] 血液脳関門突破を指向したDDSキャリアに装着したリガンド分子の標的認識能評価2018
- Author(s)
  中村乃理子,安楽泰孝、福島重人、藤加珠子、カブラル・オラシオ、片岡一則
- Organizer
  第67回高分子年次大会
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] 急性下肢虚血に対する高分子ナノ粒子を用いたドラッグデリバリー2018
- Author(s)
  三浦裕、須原正光、安楽泰孝、保科克行、カブラルオラシオ
- Organizer
  第67回高分子討論会
- Data Source
  KAKENHI-PROJECT-16H05422
[Presentation] コレステロール基修飾短鎖RNAオリゴマーを用いたmRNA内包高分子ミセルの安定化2018
- Author(s)
  吉永直人、内田智士、H. Cabral、長田健介、片岡一則
- Organizer
  第67回高分子学会年次大会
- Data Source
  KAKENHI-PROJECT-20K20386
[Presentation] Interaction between target membrane proteins and ligand-decorated polymeric micelles penetrating blood-brain barrier2018
- Author(s)
  N. Nakamura, Y. Anraku, S. Fukushima, K. Toh, H. Cabral, K. Kataoka
- Organizer
  2018 MRS fall meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H04170
[Presentation] 少数のコレステロール修飾RNAオリゴマーにより誘起されるmRNA内包高分子ミセルの構造安定化およびマウス肺局所投与への応用2018
- Author(s)
  吉永直人、内田智士、長田健介、位髙啓史、H. Cabral、片岡一則
- Organizer
  第34回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-20K20386
[Presentation] Helical polymer structure provides platinum-loaded polymeric micelles with favorable size and stability for effective tumor-targeting2018
- Author(s)
  Y. Mochida, H. Cabral, Y. Miura, K. Osada, N. Nishiyama, K. Kataoka
- Organizer
  256th ACS National Meeting & Exposition
- Data Source
  KAKENHI-PROJECT-16H05422
[Presentation] 熱コントロールによる白金制がん剤内包高分子ミセルの大幅安定化と機能制御2018
- Author(s)
  持田祐希,カブラルオラシオ、片岡一則
- Organizer
  第34回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] Design of polyplex micelles with phenylboronate ester cross-linking in the core exerting promoted gene transfection through responsivity to intracellular pH and ATP concentration2018
- Author(s)
  N. Yoshinaga, M. Naito, S. Uchida, H. Cabral, K. Osada, K. Kataoka
- Organizer
  256th ACS National Meeting & Exposition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] PEG-ポリグルタミン酸の立体構造に着目した白金錯体超分子ミセルの粒径及び腫瘍標的性の制御2017
- Author(s)
  持田祐希、H. Cabral、三浦裕、長田健介、西山伸宏、片岡一則
- Organizer
  第66回高分子討論会
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] 高分子ミセル型DDSの構造と機能に及ぼす内核構造の影響2017
- Author(s)
  持田祐希、H. Cabral、三浦裕、長田健介、西山伸宏、片岡一則
- Organizer
  第33回DDS学会学術大会
- Data Source
  KAKENHI-PROJECT-16H05422
[Presentation] 白金錯体制がん剤を内包する高分子ミセルの熱処理による安定化と機能評価2017
- Author(s)
  持田祐希、H. Cabral、片岡一則
- Organizer
  第66回高分子学会年次大会
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] フェニルボロン酸を高分子ミセルコアの架橋剤として用いるpHおよびATP応答型ｍRNAデリバリーシステムの創成-高分子ミセルの安定化およびin vitro環境での機能評価-2017
- Author(s)
  吉永直人、内藤瑞、内田智士、H. Cabral、長田健介、片岡一則
- Organizer
  第66回高分子討論会
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] An active targeting strategy against locally advanced head and neck squamous cell carcinoma harboring cancer stem-like cells via cRGD peptide-installed cisplatin-loaded nanomedicines2017
- Author(s)
  K. Miyano, H. Cabral, Y. Miura, Y. Matsumoto, Y. Mochida, H. Kinoh, N. Nishiyama, T. Yamasoba, K. Kataoka
- Organizer
  The 14th US-Japan Symposium on Drug Delivery Systems Conference
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] Ligand Strategies for Tumor-Targeted Nanomedicines2017
- Author(s)
  Horacio Cabral
- Organizer
  2nd International Symposium on Biomedical Engineering
- Invited
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] Proteasome inhibitor loaded micelles enhance antit8umor activity through macrophage reprograming by NF-κB inhibition,2017
- Author(s)
  Wu H, Tao A, Martin JD, Quader S, Liu X, Takahashi K, Hespel L, Miura Y, Hayakawa Y, Irimura T, Cabral H, Kataoka K
- Organizer
  11th Annual Symposium on Nanobiotechnology
- Place of Presentation
  Kawasaki City Hall, Kawasaki, Japan
- Data Source
  KAKENHI-PROJECT-16F16731
[Presentation] Development of porphyrin/polyaminoacid-based worm-like micelles for drug delivery2017
- Author(s)
  Y. Onuma, S. Fukushima, H. -J. Kim Y. Anraku, K. Miyata, K. Osada, H. Cabral, K. Kataoka,
- Organizer
  11th Annual Symposium on Nanobiotechnology 2017
- Place of Presentation
  Kawasaki City Industrial Promotion Hall, Kawasaki, Kanagawa,
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] Development of pH-sensitive polymeric micelles for intracellular delivery of bioactive molecules loaded through imine bond2017
- Author(s)
  A. Tao, H. Cabral, S. Quader, K. Kataoka
- Organizer
  11th Annual Symposium on Nanobiotechnology 2017
- Place of Presentation
  Kawasaki City Industrial Promotion Hall, Kawasaki, Kanagawa,
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] Overcoming biological barriers through rational design of polymeric micelles incorporating anticancer drugs2017
- Author(s)
  Yuki Mochida, Horacio Cabral, Hhiroaki Kinoh, Sabina Quader, Yutaka Miura, Nobuhiro Nishiyama, Kazunori Kataoka
- Organizer
  11th Annual Symposium on Nanobiotechnology 2017
- Place of Presentation
  Kawasaki City Industrial Promotion Hall, Kawasaki, Kanagawa
- Year and Date
  2017-02-27
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K12534
[Presentation] Enhanced activation of SN38 prodrug delivered by pH-sensitive polymeric micelle with modification of histamine on polymer side chains2017
- Author(s)
  S. Chen, S. Florinas, J. R. Christie, H. Cabral, K. Kataoka
- Organizer
  第66回高分子学会年次大会
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] 細胞外小胞の体内動態解析に向けた標識法の検討2017
- Author(s)
  乗松純平、赤木貴則、藤加珠子、J. Martin、一木隆範、片岡一則、H. Cabral
- Organizer
  第39回日本バイオマテリアル学会大会
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] Intravital assessment of drug delivery activation through hoechst-loaded polymeric micelles,2017
- Author(s)
  S. Chen, S. Florinas, K. Toh, Y. Matsumoto, J. R. Christie, K. Kataoka, H. Cabral,
- Organizer
  11th Annual Symposium on Nanobiotechnology 2017
- Place of Presentation
  Kawasaki City Industrial Promotion Hall, Kawasaki, Kanagawa,
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] 動的な腫瘍血管透過性(nano eruption)の制御2017
- Author(s)
  井上雄太、松本有、藤加珠子、宮野一樹、H. Cabral、山岨達也、片岡一則
- Organizer
  第33回DDS学会学術大会
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] Construction of PEG-rich globular non-viral gene carrier and its evaluation in hypopermeable pancreatic tumor2017
- Author(s)
  T. A. Tockary, W. Foo, K. Osada, A. Dirisala, H. Cabral, K. M. Takeda, X. Liu, K. Kataoka
- Organizer
  第66回高分子学会年次大会
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] 高分子ミセル表層に装着したリガンド分子と標的受容体との相互作用解析2017
- Author(s)
  中村乃理子、安楽泰孝、渡邉拓也、福島重人、藤加珠子、H. Cabral、片岡一則
- Organizer
  第66回高分子学会年次大会
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] Supramolecular nanomedicines for effective treatment of tumors bearing cancer stem-like cells2017
- Author(s)
  Horacio Cabral
- Organizer
  The 2017 International Advanced Drug Delivery Symposium (IADDS).
- Invited
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] フェニルボロン酸を高分子ミセルコアの架橋剤として用いるpHおよびATP応答型核酸デリバリーシステムの創成2017
- Author(s)
  吉永直人、内藤瑞、内田智士、H. Cabral、長田健介、片岡一則
- Organizer
  第66回高分子学会年次大会
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] Safe and effective transport of anti-cancer drug, thru pH-sensitive polymeric micelle.2017
- Author(s)
  S. Quader, X. Liu, H. Cabral, K. Kataoka
- Organizer
  第66回高分子学会年次大会
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] Development of staurosporine/epirubicin-loaded micelles for cooperative synergistic treatment against cancer cells and cancer stem-like cells2017
- Author(s)
  J. Martin, J. Zhang, X. Liu, H. Kinoh, H. Cabral, K. Kataoka,
- Organizer
  The 16th US-Japan Symposium on Drug Delivery Systems (Hawaii, USA)
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] Proteasome inhibitor loaded micelles enhance antitumor activity through macrophage reprograming by NF-κB inhibition2017
- Author(s)
  J. D. Martin, H. Wu, A. Tao, S. Quader, X. Liu, K. Takahashi, L. Hespel, Y. Miura, Y. Hayakawa, T. Irimura, H. Cabral, K. Kataoka
- Organizer
  11th Annual Symposium on Nanobiotechnology 2017
- Place of Presentation
  Kawasaki City Industrial Promotion Hall, Kawasaki, Kanagawa
- Year and Date
  2017-02-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05422
[Presentation] Detection of tumor hypoxic region using pH-activatable nanoparticles containing manganese contrast agent2017
- Author(s)
  D. Kokuryo, P. Mi, H. Cabral, H. Wu, Y. Terada, T. Saga, I. Aoki, N. Nishiyama, K. Kataoka
- Organizer
  ISMRM 25th Annual Meeting & Exhibition
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] Proteasome inhibitor loaded micelles enhance antitumor activity through macrophage reprogramming by NF-kB inhibition2017
- Author(s)
  John Martin, Horacio Cabral, Kazunori Kataoka
- Organizer
  Cancer Nanotechnology Gordon Research Conference, Mt. Snow, VT,
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16F16731
[Presentation] pH応答性抗癌剤ナノミセルは、 PTEN/VHL発現欠失スニチニブ耐性腎癌に対しても有効である。2017
- Author(s)
  喜納宏昭、H. Cabral、北村貴美子、片岡一則
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] Surface modification of polymeric micelle enhances their therapeutic effect against glioblastoma2017
- Author(s)
  S. Quader, X. Liu, H. Cabral, K. Kataoka
- Organizer
  4th COINS Symposium "Nanotech → In-body hospitals → Smart Life ～Future Health care with Nanomachine～"
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] Proteasome inhibitor loaded micelles enhance antitumor activity through macrophage reprogramming by NF-kB inhibition2017
- Author(s)
  J. D. Martin, H. Wu, A. Tao, S. Quader, X. Liu, K. Takahashi, L. Hespel, Y. Miura, Y. Hayakawa, T. Irimura, H. Cabral, K. Kataoka
- Organizer
  Cancer Nanotechnology Gordon Research Conference Multimodal Nano-Therapies Against Cancer
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05422
[Presentation] Cooperative Fusion of Imaging and Therapy through Theranostic Nanomedicine2017
- Author(s)
  Horacio Cabral
- Organizer
  第33回日本DDS学会(33rd Japanese DDS Conference)
- Invited
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] An active targeting strategy against locally advanced head and neck squamous cell carcinoma harboring cancer stem-like cells via cRGD peptide-installed cisplatin-loaded nanomedicines2017
- Author(s)
  K. Miyano, H. Cabral, Y. Miura, Y. Matsumoto, Y. Mochida, H. Kinoh, N. Nishiyama, T. Yamasoba, K. Kataoka
- Organizer
  The 14th US-Japan Symposium on Drug Delivery Systems Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05422
[Presentation] PEG-ポリグルタミン酸の立体構造に着目した白金錯体超分子ミセルの粒径及び腫瘍標的性の制御2017
- Author(s)
  持田祐希、H. Cabral、三浦裕、長田健介、西山伸宏、片岡一則
- Organizer
  第66回高分子討論会
- Data Source
  KAKENHI-PROJECT-16H05422
[Presentation] Proteasome inhibitor loaded micelles enhance antitumor activity through macrophage reprogramming2017
- Author(s)
  John Martin, Horacio Cabral, Kazunori Kataoka
- Organizer
  11th Annual Symposium on Nanobiotechnology, Kawasaki, Japan
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16F16731
[Presentation] Safe cancer therapy during pregnancy by using drug-loaded polymeric micelles2017
- Author(s)
  J. Wan, K. Mizuno, B. Xiong, Y. Mochida, Y. Miura, K. Kataoka, H. Cabral
- Organizer
  11th Annual Symposium on Nanobiotechnology 2017
- Place of Presentation
  Kawasaki City Industrial Promotion Hall, Kawasaki, Kanagawa
- Year and Date
  2017-02-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05422
[Presentation] Interaction analysis between ligands on the surface of nanomachine and target transporte2017
- Author(s)
  Noriko Nakamura, Y. Anraku, S. Fukushima, K. Toh, H. Cabral, K. Kataoka
- Organizer
  4th COINS Symposium "Nanotech → In-body hospitals → Smart Life ～Future Health care with Nanomachine～
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] Critical PEG shielding required for rod-shaped polyplex micelles for evading liver sinusoidal endothelial barrier to achieve improved systemic blood circulation activity2017
- Author(s)
  A. Dirisala, K. Osada, K. Toh, T. A. Tockary, H. Cabral, K. Kataoka
- Organizer
  第66回高分子学会年次大会
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] Proteasome inhibitor loaded micelles enhance antitumor activity through macrophage reprogramming by NF-kB inhibition2017
- Author(s)
  J. Martin, H. Wu, A. Tao, S. Quader, X. Liu, H. Takahashi, L. Hespel, Y. Miura, H. Hayakawa, T. Irimura, H. Cabral, K. Kataoka
- Organizer
  Gordon Research Conference. Cancer Nanotechnology
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] 活性酸素種を引き金とする抗酸化剤放出型高分子ミセルの創製2017
- Author(s)
  中村直人、吉永直人、安楽泰孝、H. Cabral、片岡一則
- Organizer
  第66回高分子討論会
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] Development of staurosporine/epirubicin-loaded micelles for cooperative synergistic treatment against cancer cells and cancer stem-like cells2017
- Author(s)
  J. Zhang, X. Liu, H. Kinoh, H. Cabral, K. Kataoka
- Organizer
  11th Annual Symposium on Nanobiotechnology 2017
- Place of Presentation
  Kawasaki City Industrial Promotion Hall, Kawasaki, Kanagawa,
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] Safe cancer therapy during pregnancy by using drug-loaded polymeric micelles,2017
- Author(s)
  J. Wan, K. Mizuno, B. Xiong, Y. Mochida, Y. Miura, K. Kataoka, H. Cabral
- Organizer
  11th Annual Symposium on Nanobiotechnology 2017
- Place of Presentation
  Kawasaki City Industrial Promotion Hall, Kawasaki, Kanagawa,
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] Development of smart polymeric micelles for ROS-triggered release of rutin2017
- Author(s)
  Naoto Nakamura, N. Yoshinaga, Y. Anraku, H. Cabral, K. Kataoka
- Organizer
  4th COINS Symposium "Nanotech → In-body hospitals → Smart Life ～Future Health care with Nanomachine～"
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] Development of pH-sensitive polymeric micelles for intracellular delivery of bioactive molecules loaded through imine bond2017
- Author(s)
  A. Tao, H. Cabral, S. Quader, K. Kataoka
- Organizer
  第39回日本バイオマテリアル学会大会
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] Cooperative Fusion of Imaging and Therapy through Theranostic Nanomedicine2017
- Author(s)
  Horacio Cabral
- Organizer
  8th Annual Symposium of the Indian Scientist Association in Japan
- Invited
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] 活性酸素種に応答して開裂する抗酸化剤内包高分子ミセルの開発2017
- Author(s)
  中村直人、安楽泰孝、吉永直人、H. Cabral、片岡一則
- Organizer
  第66回高分子学会年次大会
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] 血液脳関門の突破を指向した高分子ミセル表層のリガンド分子と標的トランスポーターの相互作用解析2017
- Author(s)
  中村乃理子、安楽泰孝、福島重人、藤加珠子、H. Cabral、片岡一則
- Organizer
  第39回日本バイオマテリアル学会大会
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] Proteasome inhibitor loaded micelles enhance antitumor activity through macrophage reprograming by NF-κB inhibition,2017
- Author(s)
  J. D. Martin, H. Wu, A. Tao, S. Quader, X. Liu, K. Takahashi, L. Hespel, Y. Miura, Y. Hayakawa, T. Irimura, H. Cabral, K. Kataoka,
- Organizer
  11th Annual Symposium on Nanobiotechnology 2017
- Place of Presentation
  Kawasaki City Industrial Promotion Hall, Kawasaki, Kanagawa,
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] Development of ROS scavenging polymeric micelles with responsivity to oxidative stress2017
- Author(s)
  中村直人、吉永直人、安楽泰孝、H. Cabral、片岡一則
- Organizer
  第39回日本バイオマテリアル学会大会
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] Supramolecular nanomedicines for effective treatment of tumors bearing cancer stem-like cells2017
- Author(s)
  Horacio Cabral
- Organizer
  International Advanced Drug Delivery Symposium
- Place of Presentation
  Hsinchu, Taiwan
- Year and Date
  2017-04-04
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] Design of polyplex micelles with intracellular environment-responsive cross-linker for efficient gene delivery - Effect of phenylboronic acid based cross-linking on intracellular trafficking -2017
- Author(s)
  N. Yoshinaga, M. Naito, S. Uchida, H. Cabral, K. Osada, K. Kataoka
- Organizer
  11th Annual Symposium on Nanobiotechnology 2017
- Place of Presentation
  Kawasaki City Industrial Promotion Hall, Kawasaki, Kanagawa,
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] pH応答性スタウロスポリン内包エピルビシンミセルは、スニチニブ耐性獲得腎癌に対しても高い抗腫瘍効果を示す2017
- Author(s)
  喜納宏昭、H. Cabral、北村貴美子、片岡一則
- Organizer
  第33回DDS学会学術大会
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] Theranostic Agents and Nanomedicine2017
- Author(s)
  H. Cabral, P. Mi, I. Aoki, N. Nishiyama, K. Kataoka
- Organizer
  International Kick-off Symposium of The Alliance for Next Generation MRI & Contrast Agents
- Invited
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] 高分子ミセル型DDSの構造と機能に及ぼす内核構造の影響2017
- Author(s)
  中村直人、吉永直人、安楽泰孝、H. Cabral、片岡一則
- Organizer
  第33回DDS学会学術大会
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] Messenger RNA-based therapeutics for the treatment of Fas-ligand induced fulminant hepatitis mouse model2016
- Author(s)
  A. Matsui, H. Cabral, Y. Miura, Y. Matsumoto, H. Kinoh, N. Nishiyama, T. Yamasoba, K. Kataoka,
- Organizer
  3rd International Conference on Biomaterials Science (ICBS2016)
- Place of Presentation
  to Hall located at The University of Tokyo, Tokyo, Japan
- Year and Date
  2016-11-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] Inhibition of lymph node metastasis and effective treatment of head and neck squamous cell carcinoma via cyclic-RGD mediated delivery of cisplatin-loaded micelles2016
- Author(s)
  宮野一樹、三浦裕、松本有、岩田要、佐谷秀行、宮園浩平、西山伸宏、H. Cabral、山岨達也、片岡一則
- Organizer
  第16回東京大学生命科学シンポジウム
- Place of Presentation
  東京大学駒場キャンパス、目黒区、東京
- Data Source
  KAKENHI-PROJECT-16H05422
[Presentation] Highly ordered core structure enhances drug delivery performance of polymeric micelles incorporating platinum anticencer agents2016
- Author(s)
  Y. Mochida, H. Cabral, Y. Miura, A. Francesco, K. Osada, N. Nishiyama, K. Kataoka
- Organizer
  10th World Biomaterials Congress
- Place of Presentation
  Montreal Convention Center, Montreal, Canada
- Year and Date
  2016-05-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K12534
[Presentation] 環状RGDペプチドを修飾した白金制がん剤内包高分子ミセルを用いたリンパ節転移／治療抵抗性がんの治療2016
- Author(s)
  持田祐希, H. Cabral, 牧野惇, 三浦裕, M. Wang, 西山伸宏, 片岡一則,
- Organizer
  第65回高分子討論会,
- Place of Presentation
  神奈川大学横浜キャンパス, 横浜市, 神奈川県
- Year and Date
  2016-09-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] Proteasome inhibitor loaded micelles enhance antitumor activity through macrophage reprograming by NF-κB inhibition2016
- Author(s)
  J. D. Martin, H. Cabral, H. Wu, S. Quader, A. Tao, W. Liu, P. Mi, K. Takahashi, Y. Hayakawa, T. Irimura, K. Kataoka
- Organizer
  3rd COINS International Symposium "Towards Smart Health Society - Challenge of Kawasaki based Medical Innovation -"
- Place of Presentation
  Kawasaki City Industrial Promotion Hall, Kawasaki, Kanagawa
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] Proteasome inhibitor loaded micelles enhance antitumor activity through macrophage reprograming by NF-κB inhibition2016
- Author(s)
  J. D. Martin, H. Cabral, H. Wu, S. Quader, A. Tao, W. Liu, P. Mi, K. Takahashi, Y. Hayakawa, T. Irimura, K. Kataoka
- Organizer
  3rd International Conference on Biomaterials Science (ICBS2016)
- Place of Presentation
  to Hall located at The University of Tokyo, Tokyo, Japan
- Year and Date
  2016-11-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] Secondary Structures in the Core of Platinum-Loaded Polymeric Micelles Improve Tumor-Targeted Drug Delivery2016
- Author(s)
  Yuki Mochida, Horacio Cabral, Yutaka Miura, Albertini Francesco, Kensuke Osada, Nobuhiro Nishiyama, Kazunori Kataoka
- Organizer
  2016 International Symposium on Nanobiotechnology
- Place of Presentation
  University of California, Los Angeles
- Year and Date
  2016-02-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K12534
[Presentation] pH-Activatable targeted nanomedicine eradicates orthotopic mesothelioma bearing recalcitrant cancer stem cell sub-population2016
- Author(s)
  H. Kinoh, Y. Miura, S. Fukushima, H. Cabral, K. Kataoka
- Organizer
  3rd International Conference on Biomaterials Science (ICBS2016)
- Place of Presentation
  to Hall located at The University of Tokyo, Tokyo, Japan
- Year and Date
  2016-11-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] Assembly of α-helical polymer chains plays a key role in tumor-targeting performance of platinum-loaded polymeric micelles2016
- Author(s)
  Y. Mochida, H. Cabral, Y. Miura, K. Osada, N. Nishiyama, K. Kataoka
- Organizer
  3rd Internatioal Conference on Biomaterials Science in Tokyo(ICBS2016)
- Place of Presentation
  Ito Hall located at The University of Tokyo, Tokyo, Japan
- Year and Date
  2016-11-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K12534
[Presentation] Brain tumor targeting by cRGD peptide encircled polymeric micelles loaded with potent antiglioblastoma agent epirubicin2016
- Author(s)
  S. Quader, X. Liu, Y. Chen, P. Mi, T. Chida, T. Ishii, Y. Miura, N. Nishiyama, H. Cabral, K. Kataoka
- Organizer
  3rd Internatioal Conference on Biomaterials Science in Tokyo(ICBS2016)
- Place of Presentation
  Ito Hall located at The University of Tokyo, Tokyo, Japan
- Year and Date
  2016-11-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05422
[Presentation] Development of staurosporine/epirubicin-loaded polymeric micelles as a robust in vivo therapy against differentiated cells and cancer stem-like cells2016
- Author(s)
  J. Zhang, H. Kinoh, T. Chida, X. Liu, Y. Miura, H. Cabral, K. Kataoka
- Organizer
  The 11th SPSJ International Polymer Conference (IPC2016)
- Place of Presentation
  Fukuoka International Confress Center, Fukuoka,
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] フェニルボロン酸を用いたATP応答型架橋ポリプレックス型高分子ミセルの創成―高分子ミセルの安定化とin vitro環境における機能検証―2016
- Author(s)
  吉永直人, 石井武彦, 遠藤泰輔, 内藤瑞, 内田智士, H. Cabral, 長田健介, 片岡一則
- Organizer
  第26回バイオ・高分子シンポジウム
- Place of Presentation
  東京工業大学大岡山キャンパス, 目黒区, 東京都
- Year and Date
  2016-07-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] フェニルボロン酸導入高分子ミセルによる扁平上皮がんの治療2016
- Author(s)
  三浦裕、田辺亜弥、H. Cabral、片岡一則
- Organizer
  第65回高分子学会年次大会
- Place of Presentation
  神戸国際会議場・展示場、神戸市、兵庫県
- Year and Date
  2016-05-25
- Data Source
  KAKENHI-PROJECT-16H05422
[Presentation] Size-modulated polymeric micelles for cancer therapy during pregnancy2016
- Author(s)
  J. Wan, K. Mizuno, B. Xiong, Y. Mochida, Y. Miura, K. Kataoka, H. Cabral
- Organizer
  3rd Internatioal Conference on Biomaterials Science in Tokyo(ICBS2016)
- Place of Presentation
  Ito Hall located at The University of Tokyo, Tokyo, Japan
- Year and Date
  2016-11-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05422
[Presentation] Assembly of α-helical polymer chains plays a key role in tumor-targeting performance of platinum-loaded polymeric micelles2016
- Author(s)
  Y. Mochida, H. Cabral, Y. Miura, K. Osada, N. Nishiyama, K. Kataoka
- Organizer
  3rd Internatioal Conference on Biomaterials Science in Tokyo(ICBS2016)
- Place of Presentation
  Ito Hall located at The University of Tokyo, Tokyo, Japan
- Year and Date
  2016-11-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05422
[Presentation] Highly ordered core structure enhances drug delivery performance of polymeric micelles incorporating platinum anticencer agents2016
- Author(s)
  Y. Mochida, H. Cabral, Y. Miura, A. Francesco, K. Osada, N. Nishiyama, K. Kataoka
- Organizer
  10th World Biomaterials Congress
- Place of Presentation
  Montreal Convention Center, Montreal, Canada
- Year and Date
  2016-05-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05422
[Presentation] Design of polyplex micelles with pH and ATP dual-responsive cross-linking for efficient gene delivery- Effect of phenylboronic acid based cross-linking on intracellular trafficking-,2016
- Author(s)
  N. Yoshinaga, M. Naito, S. Uchida, H. Cabral, K. Osada, K. Kataoka
- Organizer
  3rd International Conference on Biomaterials Science (ICBS2016)
- Place of Presentation
  to Hall located at The University of Tokyo, Tokyo, Japan
- Year and Date
  2016-11-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] A nanoparticle with pH-triggered contrast amplification ability for tumor malignancy imaging,2016
- Author(s)
  P. Mi, H. Cabral, I. Aoki, N. Nishiyama, K. Kataoka
- Organizer
  The 4th Symposium on Innovative Polymers for Controlled Delivery (SIPCD 2016),
- Place of Presentation
  Worldhotel Grand DushuLake, Suzhou, China
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] Development of pH-sensitive polymeric micelles for intracellular delivery of bioactive molecules loaded through imine bond2016
- Author(s)
  A. Tao, H. Cabral, S. Quader, 片岡一則,
- Organizer
  第65回高分子討論会
- Place of Presentation
  神奈川大学横浜キャンパス, 横浜市, 神奈川県,
- Year and Date
  2016-09-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] ドラッグ・遺伝子デリバリーのためのポルフィリン/ポリアミノ酸に基づくワーム様ミセルの開発2016
- Author(s)
  小沼由佳, 長田健介, 宮田完二郎, 片岡一則, H. Cabral
- Organizer
  第65回高分子討論会
- Place of Presentation
  神奈川大学横浜キャンパス, 横浜市, 神奈川県,
- Year and Date
  2016-09-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] 環状RGDペプチドを修飾した白金制がん剤内包ミセルのがん幹細胞治療への応用2016
- Author(s)
  持田祐希、M. Wang、H. Cabral、三浦裕、西山伸宏、片岡一則
- Organizer
  第65回高分子学会年次大会
- Place of Presentation
  神戸国際会議場・展示場、神戸市、兵庫県
- Year and Date
  2016-05-25
- Data Source
  KAKENHI-PROJECT-16H05422
[Presentation] Design of polyplex micelles with intracellular environment-responsive cross-linking for efficient gene delivery -Effect of phenylboronic acid based cross-linking on intracellular trafficking-2016
- Author(s)
  N. Yoshinaga, M. Naito, S. Uchida, H. Cabral, K. Osada, K. Kataoka
- Organizer
  The 11th SPSJ International Polymer Conference (IPC2016)
- Place of Presentation
  Fukuoka International Confress Center, Fukuoka,
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] 環状RGDペプチドを修飾した白金制がん剤内包高分子ミセルを用いたリンパ節転移／治療抵抗性がんの治療2016
- Author(s)
  持田祐希、H. Cabral、牧野惇、三浦裕、M. Wang、西山伸宏、片岡一則
- Organizer
  第65回高分子討論会
- Place of Presentation
  神奈川大学横浜キャンパス、横浜市、神奈川県
- Year and Date
  2016-09-14
- Data Source
  KAKENHI-PROJECT-15K12534
[Presentation] Development of co-drug delivery micelles for cooperative synergistic cancer treatment,2016
- Author(s)
  J. Zhang, H. Kinoh, X. Liu，H. Cabral, K. Kataoka,
- Organizer
  3rd COINS International Symposium "Towards Smart Health Society - Challenge of Kawasaki based Medical Innovation -"
- Place of Presentation
  Kawasaki City Industrial Promotion Hall, Kawasaki, Kanagawa
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] 難治性頭頸部扁平上皮癌に対するリガンド搭載シスプラチンミセルによる治療戦略2016
- Author(s)
  宮野一樹, 三浦裕, 松本有, 岩田要, 佐谷秀行, 宮園浩平, 西山伸宏, H. Cabral, 山岨達也, 片岡一則,
- Organizer
  第32回DDS学会学術大会,
- Place of Presentation
  グランシップ(静岡県コンベンションアーツセンター), 静岡市, 静岡県
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] 環状RGDペプチドを修飾した白金制がん剤内包ミセルのがん幹細胞治療への応用2016
- Author(s)
  持田祐希, M. Wang, H. Cabral, 三浦裕, 西山伸宏, 片岡一則
- Organizer
  第65回高分子学会年次大会
- Place of Presentation
  神戸国際会議場・展示場, 神戸市, 兵庫県
- Year and Date
  2016-05-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] フェニルボロン酸導入高分子ミセルによる扁平上皮がんの治療,2016
- Author(s)
  三浦裕, 田辺亜弥, H. Cabral, 片岡一則
- Organizer
  第65回高分子学会年次大会
- Place of Presentation
  神戸国際会議場・展示場, 神戸市, 兵庫県
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] Messenger RNA-based therapeutics for the treatment of Fas-ligand induced fulminant hepatitis mouse model2016
- Author(s)
  A. Matsui, H. Cabral, Y. Miura, Y. Matsumoto, H. Kinoh, N. Nishiyama, T. Yamasoba, K. Kataoka
- Organizer
  3rd Internatioal Conference on Biomaterials Science in Tokyo(ICBS2016)
- Place of Presentation
  Ito Hall located at The University of Tokyo, Tokyo, Japan
- Year and Date
  2016-11-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05422
[Presentation] Nanomedicine strategies for enhancing efficacy against head and neck squamous cell carcinoma bearing cancer stem-like cells2016
- Author(s)
  H. Cabral, K. Miyano, M. Wang, Y. Miura, Y. Matsumoto, H. Kinoh, N. Nishiyama, T. Yamasoba, K. Kataoka
- Organizer
  Frontiers2016 - Joint Symposium of the EPFL and the University of Tokyo
- Place of Presentation
  Swiss Federal Institute of Technology(EPFL), Lausanne, Switzerland
- Year and Date
  2016-12-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05422
[Presentation] Proteasome inhibitor loaded micelles enhance antit8umor activity through macrophage reprograming by NF-κB inhibition,2016
- Author(s)
  Wu H, Tao A, Martin JD, Quader S, Liu X, Takahashi K, Hespel L, Miura Y, Hayakawa Y, Irimura T, Cabral H, Kataoka K
- Organizer
  3rd International Conference on Biomaterials Science, Tokyo, Japan
- Place of Presentation
  The University of Tokyo, Tokyo, Japan
- Data Source
  KAKENHI-PROJECT-16F16731
[Presentation] Brain tumor targeting by cRGD peptide encircled polymeric micelles loaded with potent antiglioblastoma agent epirubicin2016
- Author(s)
  S. Quader, X. Liu, Y. Chen, P. Mi, T. Chida, T. Ishii, Y. Miura, N. Nishiyama, H. Cabral, K. Kataoka,
- Organizer
  3rd International Conference on Biomaterials Science (ICBS2016)
- Place of Presentation
  to Hall located at The University of Tokyo, Tokyo, Japan
- Year and Date
  2016-11-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] 難治性頭頸部扁平上皮癌に対するリガンド搭載シスプラチンミセルによる治療戦略2016
- Author(s)
  宮野一樹、三浦裕、松本有、岩田要、佐谷秀行、宮園浩平、西山伸宏、H. Cabral、山岨達也、片岡一則
- Organizer
  第32回DDS学会学術大会
- Place of Presentation
  グランシップ(静岡県コンベンションアーツセンター)、静岡市、静岡県
- Year and Date
  2016-06-30
- Data Source
  KAKENHI-PROJECT-16H05422
[Presentation] Development of porphyrin/polyaminoacid-based worm-like micelles for drug delivery2016
- Author(s)
  Y. Onuma, S. Fukushima, K. Toh, H. Cabral, K. Kataoka,
- Organizer
  3rd International Conference on Biomaterials Science (ICBS2016)
- Place of Presentation
  to Hall located at The University of Tokyo, Tokyo, Japan
- Year and Date
  2016-11-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] Size-modulated polymeric micelles for cancer therapy during pregnancy2016
- Author(s)
  J. Wan, K. Mizuno, B. Xiong, Y. Mochida, Y. Miura, K. Kataoka, H. Cabral
- Organizer
  3rd International Conference on Biomaterials Science (ICBS2016)
- Place of Presentation
  to Hall located at The University of Tokyo, Tokyo, Japan,
- Year and Date
  2016-11-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] Assembly of α-helical polymer chains plays a key role in tumor-targeting performance of platinum-loaded polymeric micelles2016
- Author(s)
  Y. Mochida, H. Cabral, Y. Miura, K. Osada, N. Nishiyama, K. Kataoka
- Organizer
  3rd International Conference on Biomaterials Science (ICBS2016)
- Place of Presentation
  to Hall located at The University of Tokyo, Tokyo, Japan
- Year and Date
  2016-11-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] Highly ordered core structure enhances drug delivery performance of polymeric micelles incorporating platinum anticencer agents2016
- Author(s)
  Y. Mochida, H. Cabral, Y. Miura, A. Francesco, K. Osada, N. Nishiyama, K. Kataoka
- Organizer
  10th World Biomaterials Congress
- Place of Presentation
  Montreal, Canada
- Year and Date
  2016-05-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] pH-Activatable targeted nanomedicine eradicates orthotopic mesothelioma bearing recalcitrant cancer stem cell sub-population2016
- Author(s)
  H. Kinoh, Y. Miura, S. Fukushima, H. Cabral, K. Kataoka
- Organizer
  3rd Internatioal Conference on Biomaterials Science in Tokyo(ICBS2016)
- Place of Presentation
  Ito Hall located at The University of Tokyo, Tokyo, Japan
- Year and Date
  2016-11-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05422
[Presentation] Effective treatment of locally advanced head and neck squamous cell carcinoma bearing cancer stem-like cells by cRGD peptide-installed cisplatin-loaded micelles2016
- Author(s)
  K. Miyano, H. Cabral, Y. Miura, Y. Matsumoto, H. Kinoh, N. Nishiyama, T. Yamasoba, K. Kataoka
- Organizer
  3rd Internatioal Conference on Biomaterials Science in Tokyo(ICBS2016)
- Place of Presentation
  Ito Hall located at The University of Tokyo, Tokyo, Japan
- Year and Date
  2016-11-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05422
[Presentation] Effective treatment of locally advanced head and neck squamous cell carcinoma bearing cancer stem-like cells by cRGD peptide-installed cisplatin-loaded micelles2016
- Author(s)
  K. Miyano, H. Cabral, Y. Miura, Y. Matsumoto, H. Kinoh, N. Nishiyama, T. Yamasoba, K. Kataoka,
- Organizer
  3rd International Conference on Biomaterials Science (ICBS2016)
- Place of Presentation
  to Hall located at The University of Tokyo, Tokyo, Japan
- Year and Date
  2016-11-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] 環状RGDペプチドを修飾した白金制がん剤内包ミセルのがん幹細胞治療への応用2016
- Author(s)
  持田祐希、M. Wang、H. Cabral、三浦裕、西山伸宏、片岡一則
- Organizer
  第65回高分子学会年次大会
- Place of Presentation
  神戸国際会議場・展示場、神戸市、兵庫県
- Year and Date
  2016-05-25
- Data Source
  KAKENHI-PROJECT-15K12534
[Presentation] Development of staurosporine/epirubicin-loaded polymeric micelles as a robust in vivo therapy against differentiated cells and cancer stem-like cells2016
- Author(s)
  J. Zhang, H. Kinoh, T. Chida, X. Liu, Y. Miura, H. Cabral, K. Kataoka
- Organizer
  The 11th SPSJ International Polymer Conference (IPC2016)
- Place of Presentation
  Fukuoka International Confress Center, Fukuoka
- Year and Date
  2016-12-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05422
[Presentation] Intravital assessment of drug delivery activation through hoechst-loaded polymeric micelles,2016
- Author(s)
  S. Chen, S. Florinas, K. Toh, Y. Matsumoto, J. R. Christie, H. Cabral, K. Kataoka,
- Organizer
  The 11th SPSJ International Polymer Conference (IPC2016)
- Place of Presentation
  Fukuoka International Confress Center, Fukuoka,
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] 環状RGDペプチドを修飾した白金制がん剤内包高分子ミセルを用いたリンパ節転移／治療抵抗性がんの治療2016
- Author(s)
  持田祐希、H. Cabral、牧野惇、三浦裕、M. Wang、西山伸宏、片岡一則
- Organizer
  第65回高分子討論会
- Place of Presentation
  神奈川大学横浜キャンパス、横浜市、神奈川県
- Year and Date
  2016-09-14
- Data Source
  KAKENHI-PROJECT-16H05422
[Presentation] Ultrasmall DNA-loaded spherical polyplex micelles and their evaluation in hypovasculature pancreatic tumor2016
- Author(s)
  T. A. Tockary, K. Osada, W. Foo, A. Dirisala, K. M. Takeda, H. Cabral, X. Liu, K. Kataoka,
- Organizer
  3rd International Conference on Biomaterials Science (ICBS2016)
- Place of Presentation
  to Hall located at The University of Tokyo, Tokyo, Japan
- Year and Date
  2016-11-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] anomedicine strategies for enhancing efficacy against head and neck squamous cell carcinoma bearing cancer stem-like cells2016
- Author(s)
  H. Cabral, K. Miyano, M. Wang, Y. Miura, Y. Matsumoto, H. Kinoh, N. Nishiyama, T. Yamasoba, K. Kataoka,
- Organizer
  Frontiers2016 - Joint Symposium of the EPFL and the University of Tokyo,
- Place of Presentation
  Swiss Federal Institute of Technology(EPFL)Lausanne, Switzerland,
- Year and Date
  2016-12-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] Higher-Order Structure of Poly(glutamic acid) Enhances Drug Delivery Performance of Anticancer Platinum-Loaded Polymeric Micelles2015
- Author(s)
  Yuki Mochida, Horacio Cabral, Yutaka Miura, Albertini Francesco, Kensuke Osada, Nobuhiro Nishiyama, Kazunori Kataoka
- Organizer
  IUPAC 11th International Conference on Advanced Polymers via Macromolecular Engineering
- Place of Presentation
  Pacifico Yokohama
- Year and Date
  2015-10-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K12534
[Presentation] 環状RGDペプチドを搭載した白金錯体制がん剤内包ミセルのがん幹細胞治療への展開2015
- Author(s)
  ○持田祐希, Ming Wang, 三浦裕, Horacio Cabral, 西山伸宏, 片岡一則
- Organizer
  第64回高分子学会年次大会
- Place of Presentation
  札幌コンベンションセンター
- Year and Date
  2015-05-27
- Data Source
  KAKENHI-PROJECT-15K12534
[Presentation] Supramolecular Nanosystem Design for Eradication of Cancer Stem Cells2015
- Author(s)
  H. Cabral, K. Kataoka
- Organizer
  2nd CMS International Symposium
- Place of Presentation
  Lecture room 305, Shiiki Hall, Ito Campus, Kyushu University
- Year and Date
  2015-01-20
- Invited
- Data Source
  KAKENHI-PROJECT-25750172
[Presentation] 白金制がん剤を内包する高分子ミセルの安定性及び機能を決定する内核高次構造2015
- Author(s)
  持田祐希, Horacio Cabral, 三浦裕, Francesco Albertini, 長田健介, 西山伸宏, 片岡一則
- Organizer
  第64回高分子討論会
- Place of Presentation
  東北大学川内キャンパス
- Year and Date
  2015-09-15
- Data Source
  KAKENHI-PROJECT-15K12534
[Presentation] Intracellular delivery of proteasome inhibitor MG132 by using polymeric micelles for effective cancer therapy2013
- Author(s)
  Sabina Quader, Horacio Cabral, 他4名
- Organizer
  2nd Internat. Conf. on Biomaterials Sci. in Tsukuba -ICBS2013-
- Place of Presentation
  つくば国際会議場（茨城県）
- Data Source
  KAKENHI-PROJECT-23700526
[Presentation] Intravital Microscopy for DDS Evaluation and Development2013
- Author(s)
  Y. Matsumoto, T. Nomoto, K. Toh, K. Miyano, H. Cabral, M.Murakami, R. J. Christie, T. A. Tockary, K. Osada, Y. Miura, N. Nishiyama, T. Yamasoba, K. Kataoka
- Organizer
  The 12th US-Japan Symposium on Drug Delivery Systems (Hawaii, USA)
- Place of Presentation
  Hawaii, USA
- Data Source
  KAKENHI-PROJECT-25750172
[Presentation] PEGylated polyanion hybrid calcium phosphate micellar MRI probe for in vivo noninvasive solid tumor diagnosis2013
- Author(s)
  Peng Mi, Horacio Cabral 他5名
- Organizer
  16th International Symposium on RECENT ADVANCES IN DRUG DELIVERY SYSTEMS
- Place of Presentation
  Salt Lake City (USA)
- Data Source
  KAKENHI-PROJECT-23700526
[Presentation] Systemically injected polymeric micelles can inhibit the growth of lymph node metastasis2013
- Author(s)
  H. Cabral, Jun Makino, Yu Matsumoto, Yutaka Miura, Mitsunobu Kano, Nobuhiro Nishiyama, Kazunori Kataoka Frontiers 2013 (Lausanne, Switzerland)
- Organizer
  Frontiers 2013-Joint EPFL/University of Tokyo Symposium on "Frontiers in Nanomedicine and Imaging"
- Place of Presentation
  Laussane, Switzerland
- Data Source
  KAKENHI-PROJECT-25750172
[Presentation] PEGylated Polyanion Hybrid Calcium Phosphate Micellar MRI Probe for In Vivo Noninvasive Solid Tumor Diagnosis2013
- Author(s)
  Peng Mi, Daisuke Kokuyo, Michiaki Kumagai, Horacio Cabral, Ichio Aoki, Nobuhiro Nishiyama, Kazunori Kataoka
- Organizer
  16th International Symposium on RECENTADVANCES IN DRUG DELIVERY SYSTEMS
- Place of Presentation
  Salt Lake City (USA)
- Data Source
  KAKENHI-PROJECT-23700526
[Presentation] Secondary Structure of PEG-b-Poly(Glutamic Acid) Copolymer Determines the Drug Delivery Efficiency of Cisplatin-Loaded Polymeric Micelles2013
- Author(s)
  Yuki Mochida, Francesco Albertini, Horacio Cabral, Yutaka Miura, KensukeOsada, Nobuhiro Nishiyama, Kazunori Kataoka
- Organizer
  16th International Symposium on RECENT ADVANCES IN DRUG DELIVERY SYSTEMS
- Place of Presentation
  Salt Lake City (USA)
- Data Source
  KAKENHI-PROJECT-23700526
[Presentation] Optimization of c-RGD peptide on the surface of Polymeric micelles, incorporating Epirubicin, for superior antitumor efficacy.2013
- Author(s)
  S. Quander, J. Makino, H. Cabral, T. Ishii, Y. Miura, N. Nishiyama, K. Kataoka
- Organizer
  The 13th Pacific Polymer Conference
- Place of Presentation
  Kaohsiung, Taiwan
- Data Source
  KAKENHI-PROJECT-25750172
[Presentation] Secondary structure of PEG-b-poly(glutamic acid) copolymer determines the drug delivery efficiency of cisplatin-loaded polymeric micelles2013
- Author(s)
  Yuki Mochida, Horacio Cabral 他5名
- Organizer
  16th International Symposium on RECENT ADVANCES IN DRUG DELIVERY SYSTEMS
- Place of Presentation
  Salt Lake City (USA)
- Data Source
  KAKENHI-PROJECT-23700526
[Presentation] Intracellular delivery of proteasome inhibitor MG132 by using polymeric micelles for effective cancer therapy2013
- Author(s)
  Sabina Quader, Horacio Cabral, Yuki Mochida, Takehiko Ishii, Nobuhiro Nishiyama, Kazunori Kataoka
- Organizer
  2nd International Conference on Biomaterials Science in Tsukuba ICBS2013
- Place of Presentation
  つくば国際会議場
- Data Source
  KAKENHI-PROJECT-23700526
[Presentation] Targeting cancer stem cells with platinum anti-cancer drug-incorporated polymeric micelles2013
- Author(s)
  M. Wang, Y. Miura, H. Cabral, N. Nishiyama, K. Kataoka
- Organizer
  European Cancer Congress 2013
- Place of Presentation
  Amsterdam, Netherlands
- Data Source
  KAKENHI-PROJECT-25750172
[Presentation] Structure and enhanced pharmacokinetics of antitumor platinum-loaded micelles regulated by secondary structure in their core2012
- Author(s)
  Yuki Mochida;Horacio Cabral; 他5名
- Organizer
  The 9th International Polymer Conference（IPC2012)
- Place of Presentation
  神戸コンベンションセンター（兵庫県）
- Data Source
  KAKENHI-PROJECT-23700526
[Presentation] 悪性脳腫瘍を標的としたリガンド介在型ドラッグデリバリーシステムの開発2012
- Author(s)
  三浦裕、Horacio Cabral, 他2名
- Organizer
  第28回日本DDS学会学術集会
- Place of Presentation
  札幌コンベンションセンター（北海道）
- Data Source
  KAKENHI-PROJECT-23700526
[Presentation] がんのリンパ行性転移に対する高分子ミセル型DDSのターゲティング能に関する研究2012
- Author(s)
  牧野　惇, Horacio Cabral 他3名
- Organizer
  第28回日本DDS学会学術集会
- Place of Presentation
  札幌コンベンションセンター（北海道）
- Data Source
  KAKENHI-PROJECT-23700526
[Presentation] Preparation and Characterization of pH-responsive Polymeric Micelles Incorporating the Proteasome Inhibitor MG132 for Efficient Cancer Therapy2012
- Author(s)
  Sabina Quader, Horacio Cabral, Takehiko Ishii, Yutaka Miura, Nobuhiro Nishiyama, Kazunori Kataoka
- Organizer
  The 39th Annual Meeting & Exposition of the Controlled Release Society
- Place of Presentation
  Centre des congres de Quebec, Quebec City (Canada)
- Data Source
  KAKENHI-PROJECT-23700526
[Presentation] Size-mediated accumulation of sub-100 nm polymeric micelles in poorly permeable tumors2012
- Author(s)
  Horacio Cabral, Yu Matsumoto, Mitsunobu R. Kano, Nobuhiro Nishiyama, Kazunori Kataoka
- Organizer
  第28回日本DDS学会学術集会
- Place of Presentation
  札幌コンベンションセンター
- Data Source
  KAKENHI-PROJECT-23700526
[Presentation] Calcium Phosphate Hybrid Micelles Incorporating Gd-DTPA with Enhance Relaxivity for Magnetic Resonance Imaging2012
- Author(s)
  Peng Mi;Horacio Cabral; 他2名
- Organizer
  The 9th International Polymer Conference（IPC2012)
- Place of Presentation
  神戸コンベンションセンター（兵庫県）
- Data Source
  KAKENHI-PROJECT-23700526
[Presentation] Gd-DTPA loaded polymeric micelle with high relaxivity for in vivo cancer diagnosis2012
- Author(s)
  Mi Peng, Horacio Cabral 他5名
- Organizer
  9th World Biomaterials Congress
- Place of Presentation
  Chengdu　(China)
- Data Source
  KAKENHI-PROJECT-23700526
[Presentation] Structure and enhanced pharmacokinetics of antitumor platinum-loaded micelles regulated by secondary structure in their core2012
- Author(s)
  Yuki Mochida, Francesco Albertini, Horacio Cabral, Yutaka Miura, Kensuke Osada, Nobuhiro Nishiyama, Kazunori Kataoka
- Organizer
  The 9th International Polymer Conference (IPC2012)
- Place of Presentation
  神戸コンベンションセンター
- Data Source
  KAKENHI-PROJECT-23700526
[Presentation] Development of a polyion complex polymersome (PICsome) containing surfactant micelles with hydrophobic drugs in aqueous interior2012
- Author(s)
  Masato Sasano,Horacio Cabral 他4名
- Organizer
  The 61st Symposium on Macromolecules
- Place of Presentation
  名古屋工業大学（愛知県）
- Data Source
  KAKENHI-PROJECT-23700526
[Presentation] αヘリックス構造形成に基づくPEG-ポリグルタミン酸ブロック共重合体/制がん剤ダハプラチン内包高分子ミセルの機能向上2012
- Author(s)
  持田祐希、Francesco Albertini, Horacio Cabral,三浦裕,長田健介,西山伸宏,片岡一則
- Organizer
  第61回高分子討論会
- Place of Presentation
  名古屋工業大学
- Data Source
  KAKENHI-PROJECT-23700526
[Presentation] Size-mediated accumulation of sub-100 nm polymeric micelles in poorly permeable tumors2012
- Author(s)
  Horacio Cabral, 他4名
- Organizer
  第28回日本DDS学会学術集会
- Place of Presentation
  札幌コンベンションセンター（北海道）
- Data Source
  KAKENHI-PROJECT-23700526
[Presentation] Targeting of early inflammatory metastatic sites by using drug-loaded polymeric micelles2012
- Author(s)
  Huailiang Wu, Horacio Cabral, 他4名
- Organizer
  第28回日本DDS学会学術集会
- Place of Presentation
  札幌コンベンションセンター（北海道）
- Data Source
  KAKENHI-PROJECT-23700526
[Presentation] がんのリンパ行性転移に対する高分子ミセル型DDSのターゲティング能に関する研究2012
- Author(s)
  牧野惇、Horacio Cabral、松本有、三浦裕、狩野光伸、西山伸宏、片岡一則
- Organizer
  第28回日本DDS学会学術集会
- Place of Presentation
  札幌コンベンションセンター
- Data Source
  KAKENHI-PROJECT-23700526
[Presentation] Preparation of antibody introduced micelle consist of well defined end-functionalized poly(ethylene oxide)- b-poly(amino acid)2012
- Author(s)
  Jooyeon Ahn;Horacio Cabral; 他4名
- Organizer
  The 9th International Polymer Conference（IPC2012)
- Place of Presentation
  神戸コンベンションセンター（兵庫県）
- Data Source
  KAKENHI-PROJECT-23700526
[Presentation] Preparation and Characterisation of pH-responsive Polymeric Micelles Incorporating the Proteasome Inhibitor MG132 for Efficient Cancer Therapy2012
- Author(s)
  Sabina Quader、Horacio Cabral　他5名
- Organizer
  2012 CRS Annual Meeting
- Place of Presentation
  Centre des congrès de Québec Québec City (Canada)
- Data Source
  KAKENHI-PROJECT-23700526
[Presentation] Polymeric micelles inhibit the growth of lymph node metastasis after intravenous injection2012
- Author(s)
  Horacio Cabral 他5名
- Organizer
  NanoBioSeattle
- Place of Presentation
  Seattle (USA)
- Data Source
  KAKENHI-PROJECT-23700526
[Presentation] 悪性脳腫瘍を標的としたリガンド介在型ドラッグデリバリーシステムの開発2012
- Author(s)
  三浦裕、Horacio Cabral、西山伸宏、片岡一則
- Organizer
  第28回日本DDS学会学術集会
- Place of Presentation
  札幌コンベンションセンター
- Data Source
  KAKENHI-PROJECT-23700526
[Presentation] 白金錯体制がん剤内包ミセルのコア高次構造が形態及び薬剤機能に及ぼす影響2012
- Author(s)
  持田祐希, Horacio Cabral 他5名
- Organizer
  The 61st SPSJ Annual meeting
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Data Source
  KAKENHI-PROJECT-23700526
[Presentation] Targeting of early inflammatory metastatic sites by using drug-loaded polymeric micelles2012
- Author(s)
  Hailiang Wu, Horacio Cabral, Nobuhiro Nishiyama, Kazunori Kataoka
- Organizer
  第28回日本DDS学会学術集会
- Place of Presentation
  札幌コンベンションセンター
- Data Source
  KAKENHI-PROJECT-23700526
[Presentation] Ichio Aoki, Kazunori Kataoka, Gd-DTPA loaded polymeric micelle with high relaxivity for in vivo cancer diagnosis2012
- Author(s)
  Peng Mi, Horacio Cabral , Sachiko Kaida, Daisuke Kokuryo, Nobuhiro Nishiyama
- Organizer
  9th World Biomaterials Congress
- Place of Presentation
  Chengdu (China)
- Data Source
  KAKENHI-PROJECT-23700526
[Presentation] Improved function of antitumor DACHPt-loaded polymeric micelles based on α -helical structure of PEG-b -poly(glutamic acid)2012
- Author(s)
  Yuki Mochida, Horacio Cabral 他5名
- Organizer
  The 61st Symposium on Macromolecules
- Place of Presentation
  名古屋工業大学（愛知県）
- Data Source
  KAKENHI-PROJECT-23700526
[Presentation] Developing pH-responsive Polymer Micelles for the intracellular delivery of Proteasome inhibitor M132 for effective cancer therapy2012
- Author(s)
  Sabina Quader;Horacio Cabral; 他4名
- Organizer
  The 9th International Polymer Conference（IPC2012)
- Place of Presentation
  神戸コンベンションセンター（兵庫県）
- Data Source
  KAKENHI-PROJECT-23700526
[Presentation] Polymeric Micelles Can Treat Lymph Node Metastasis After Intravenous Injection2012
- Author(s)
  Horacio Cabral, Jun Makino, TakahiroNomoto, Mitsunobu R. Kano, Nobuhiro Nishiyama, Kazunori Kataoka
- Organizer
  NanoBio Seattle 2012 (The Fourth International NanoBio Conference)
- Place of Presentation
  Seattle (USA)
- Data Source
  KAKENHI-PROJECT-23700526
[Presentation] Formation and sustained-dissociation of antitumor platinum-loaded micelles regulated by secondary structure of poly(amino acids) in their core2012
- Author(s)
  Yuki Mochida, Horacio Cabral 他5名
- Organizer
  9th World Biomaterials Congress
- Place of Presentation
  Chengdu　(China)
- Data Source
  KAKENHI-PROJECT-23700526
[Presentation] Formation and sustained-dissociation of antitumor platinum-loaded micelles regulated by secondary structure in their core2012
- Author(s)
  Yuki Mochida, Francesco Albertini, Horacio Cabral, Yutaka Miura, Kensuke Osada, Nobuhiro Nishiyama, KazunoriKataoka
- Organizer
  9th World Biomaterials Congress
- Place of Presentation
  Chengdu (China)
- Data Source
  KAKENHI-PROJECT-23700526
[Presentation] Developing pH-responsive Polymer Micelles for the intracellular delivery of Proteasome inhibitor M132 for effective cancer therapy2012
- Author(s)
  Sabina Quader, Horacio Cabral, Takehiko Ishii, Yutaka Miura, Nobuhiro Nishiyama, Kazunori Kataoka
- Organizer
  The 9th International PolymerConference (IPC 2012)
- Place of Presentation
  神戸コンベンションセンター
- Data Source
  KAKENHI-PROJECT-23700526
[Presentation] 白金錯体制がん剤内包ミセルのコア高次構造が形態及び薬剤機能に及ぼす影響2012
- Author(s)
  持田祐希、Francesco Albertini、Horacio Cabral、三浦裕、長田健介、西山伸宏、片岡一則
- Organizer
  第61回高分子年次大会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23700526
[Presentation] 疎水性薬剤を内包したポリイオンコンプレックス型ベシクルPICsomeの開発2012
- Author(s)
  笹野将人、安楽泰孝、岸村顕広、Horacio Cabral、西山伸宏、片岡一則
- Organizer
  第61回高分子討論会
- Place of Presentation
  名古屋工業大学
- Data Source
  KAKENHI-PROJECT-23700526
[Presentation] Development of a glutathione sensitive polymeric micelles for the delivery of campothecin to solid tumors
- Author(s)
  H.-C. Yen, H. Cabral, H. Koori, Y. Miura, P. Mi, A. Kim, N. Nishiyama, K. Kataoka
- Organizer
  41st Annual Meeting & Exposition of the Controlled Release Society
- Place of Presentation
  The Hilton Chicago, Chicago, Illinois, USA
- Year and Date
  2014-07-13 – 2014-07-16
- Data Source
  KAKENHI-PROJECT-25750172
[Presentation] Intracerebral drug delivery treatment using a regularly-structured biodegradable gel for slow-release of gadolinium-containing nano-micelles in a glioblastoma model
- Author(s)
  D. Kokuryo, P. Mi, T. Kurita, T. Yatabe, H. Cabral, S. Shibata, Y. Muragaki, H. Iseki, T. Sakai, U. -I. Chung, N. Nishiyama, T. Saga, I. Aoki, K. Kataoka
- Organizer
  Joint Annual Meeting ISMRM-ESMRMB 2014
- Place of Presentation
  Milano Congressi, Milano, Italy
- Year and Date
  2014-05-10 – 2014-05-16
- Data Source
  KAKENHI-PROJECT-25750172
[Presentation] αヘリックスを基盤とするコアの高次構造がシスプラチンを内包する高分子ミセルの制がん効果に及ぼす影響
- Author(s)
  持田祐希、H. Cabral、三浦裕、F. Albertini、長田健介、西山伸宏、片岡一則
- Organizer
  第63回高分子学会年次大会
- Place of Presentation
  名古屋国際会議場、名古屋市、愛知県
- Year and Date
  2014-05-28 – 2014-05-30
- Data Source
  KAKENHI-PROJECT-25750172
[Presentation] Metallosomes as bioactive polymersomes formed by supramolecular assembly of block copolymer-metal complexation
- Author(s)
  K. Osada, H. Cabral, Y. Mochida, Y. Anraku, A. Kishimura, N. Nishiyama, K. Kataoka
- Organizer
  248th American Chemical Society (ACS) National Meeting & Exposition
- Place of Presentation
  Moscone Center, San Francisco, California, USA
- Year and Date
  2014-08-10 – 2014-08-14
- Data Source
  KAKENHI-PROJECT-25750172
[Presentation] シスプラチン内包PEG-ポリ(L-グルタミン酸)ブロック共重合体ミセルの制がん効果に及ぼす内核ヘリックスバンドル構造の影響
- Author(s)
  持田祐希、H. Cabral、三浦裕、長田健介、西山伸宏、片岡一則
- Organizer
  第23回ポリマー材料フォーラム
- Place of Presentation
  奈良県新公会堂、奈良市、奈良県
- Year and Date
  2014-11-06 – 2014-11-07
- Data Source
  KAKENHI-PROJECT-25750172
[Presentation] 金属配位結合を駆動力とした中空ナノ粒子構築とDDSへの応用
- Author(s)
  長田健介、H. Cabral、持田祐希、安楽泰孝、岸村顕広、西山伸宏、片岡一則
- Organizer
  第24回バイオ・高分子シンポジウム
- Place of Presentation
  東京工業大学大岡山キャンパス、目黒区、東京都
- Year and Date
  2014-07-24 – 2014-07-25
- Data Source
  KAKENHI-PROJECT-25750172
[Presentation] 白金錯体制がん剤を内包する高分子ミセルのin vivo抗腫瘍効果に与える高分子高次構造の影響
- Author(s)
  持田祐希、H. Cabral、三浦裕、F. Albertini、長田健介、西山伸宏、片岡一則
- Organizer
  第43回医用高分子シンポジウム
- Place of Presentation
  産業技術総合研究所臨海副都心センター、江東区、東京都
- Year and Date
  2014-07-28 – 2014-07-29
- Data Source
  KAKENHI-PROJECT-25750172
[Presentation] Systemic targeting of lymph node metastasis by controlled design of drug-loaded polymeric micelles
- Author(s)
  J. Makino, H. Cabral, Y. Miura, Y. Matsumoto, H. Kinoh, N. Nishiyama, K. Kataoka
- Organizer
  12th International Nanomedicine and Drug Delivery Symposium (NanoDDS'14)
- Place of Presentation
  UNC Eshelman School of Pharmacy and Duke University, North Carolina, USA
- Year and Date
  2014-10-06 – 2014-10-08
- Data Source
  KAKENHI-PROJECT-25750172
[Presentation] Targeting intractable tumors and metastasis by using supramolecular nanodevices
- Author(s)
  H. Cabral
- Organizer
  12th International Nanomedicine and Drug Delivery Symposium (NanoDDS'14)
- Place of Presentation
  UNC Eshelman School of Pharmacy and Duke University, North Carolina, USA
- Year and Date
  2014-10-06 – 2014-10-08
- Invited
- Data Source
  KAKENHI-PROJECT-25750172
[Presentation] Supramolecular nanodevices for cancer diagnosis and therapy
- Author(s)
  H. Cabral
- Organizer
  Seminar at MedImmune
- Place of Presentation
  1MedImmune Way, Gathersburg, Washington, USA
- Year and Date
  2014-10-08 – 2014-10-10
- Invited
- Data Source
  KAKENHI-PROJECT-25750172
[Presentation] Polymeric micelles loaded with platinum anticancer drugs target preangiogenic micrometastatic niches associated with inflammation
- Author(s)
  H. Wu, H. Cabral, K. Toh, P. Mi, Y. Matsumoto, J. -Y. Ahn, H. Kinoh, N. Nishiyama, Y. Miura, K. Kataoka
- Organizer
  The 10th International Polymer Conference IPC2014
- Place of Presentation
  International Congress Center, Tsukuba, Ibaraki
- Year and Date
  2014-12-02 – 2014-12-05
- Data Source
  KAKENHI-PROJECT-25750172
[Presentation] Development of a specific targeting system for pancreatic tumors utilizing antibody conjugated Pt-loaded micelles
- Author(s)
  J. -Y. Ahn, N. Yamada, A. Kim, T. Chida, Y. Miura, H. Cabral, Y. Matsumura, N. Nishiyama, K. Kataoka
- Organizer
  41st Annual Meeting & Exposition of the Controlled Release Society
- Place of Presentation
  The Hilton Chicago, Chicago, Illinois, USA
- Year and Date
  2014-07-13 – 2014-07-16
- Data Source
  KAKENHI-PROJECT-25750172

1. Mochida Yuki (60739134)

# of Collaborated Projects: 7 results

# of Collaborated Products: 27 results
2. Kataoka Kazunori (00130245)

# of Collaborated Projects: 4 results

# of Collaborated Products: 37 results
3. 喜納宏昭 (70283067)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
4. Aoki Ichio (10319519)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
5. 田畑泰彦 (50211371)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 宮島大吾 (60707826)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 内田智士 (20710726)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
8. 劉学瑩 (30777470)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
9. 小嶋基寛 (30338470)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
10. Miura Yutaka (40557980)

# of Collaborated Projects: 1 results

# of Collaborated Products: 23 results
11. MIZUNO KAZUE (80615972)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. Kaida Sachiko (70710234)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 永松健 (60463858)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
14. 小山博之 (10241994)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 仲成幸 (10359771)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 谷眞至 (60236677)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 津本浩平 (90271866)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 垣見和宏 (80273358)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 横田秀夫 (00261206)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 弓場英司 (80582296)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 河合裕子 (90555616)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 武藤淳 (30383839)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 峯裕 (10306730)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 金蔵孝介 (10508568)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 上甲眞宏 (20440729)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 廣瀬雄一 (60218849)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 井上辰志 (80304434)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 松元亮 (70436541)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 宮崎拓也 (80844779)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. Quader Sabina (90749699)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
31. 中川泰宏 (90831264)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
32. 佐藤守俊 (00323501)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. 鈴木利宙 (50530135)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. Mohamed Aziz・Awaad・Aziz (50978286)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. 藤加珠子 (90342732)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
36. WAN Jingyu

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
37. MARTIN JOHN

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
38. CHEN PENGWEN

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
39. HOSHINA Katsuyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
40. OSADA Kensuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
41. ODA Katsutoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
42. MATSUMOTO Yu

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
43. KISHIMURA Akihiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
44. 赤木大輔

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
45. MI P.

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results
46. MI Peng

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results
47. 西山伸宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 11 results
48. 野本貴大

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
49. ZHENG Meng

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results

Cabral Horacio Ｃａｂｒａｌ Ｈｏｒａｃｉｏ

CABRAL Horacio CABRAL Horacio

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難治性KRAS駆動型膵臓がんに対する革新的な遺伝子編集治療法の開発Principal Investigator

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Development of Innovative Cancer Genome Editing Therapy Using Polymeric Micelles Implementing High Precision Intracellular Delivery FunctionPrincipal Investigator

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mRNA therapy for the treatment of autoimmune diseases that produces chimeric antigen receptor regulatory T cells in vivoPrincipal Investigator

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Development of nanotherapeutic agents that boost immunotherapy by precision targeting of cancer-related fibroblastsPrincipal Investigator

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Cancer immunotherapy by in vivo generation of CAR T cells based on targeted mRNA deliveryPrincipal Investigator

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Development of mRNA drug with RNA type aptamer conferring cell type specific translation activation functionPrincipal Investigator

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Cabral Horacio ＣａｂｒａｌＨｏｒａｃｉｏ