KASE Ryoichi 加瀬良一

… Alternative Names

KASE Ryouichi 加瀬良一

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Researcher Number	20150203
Affiliation (based on the past Project Information) *help	2000 – 2002: 財団法人東京都医学研究機構, 東京都臨床医学総合研究所, 研究員 1999 – 2000: 財団法人東京都医学研究機構, 東京都臨床医学総合研究所, 研究員 1998: 東京都臨床医学総合研究所, 臨床遺伝, 研究員 1998: 財団法人東京都臨床医学総合研究所, 臨床遺伝学研究部門, 研究員 1998: Tokyo Metro.Institute of Med.Science, Researcher, 臨床遺伝, 研究員 … More 1998: The Tokyo Metropolitan Institute of Medical Science, Department of Clinical Gene, 臨床遺伝学研究部門, 研究員 1997: (財)東京都臨床医学総合研究所, 臨床遺伝・, 研究員 1997: (財)東京都臨床医学総合研究所, 臨床遺伝学研究部門, 研究員 1996: 財団法人東京都臨床医学総合研究所, 臨床遺伝学研究部門, 研究員 1993: 財団法人東京都臨床医学総合研究所, 臨床遺伝学研究部門, 研究員 1993: The Tokyo Metropolitan Institute of Medical Science, Department of Clinical Gene, 臨床遺伝学研究部門, 研究員 1992: (財)東京都臨床医学総合研究所, 臨床遺伝学研究部門, 研究員 1991 – 1992: 東京都臨床医学総合研究所, 臨床遺伝学, 研究員 1991: 財団法人東京都臨床医学総合研究所, 臨床遺伝学研究部門, 研究員 1987 – 1988: (財)東京都臨床医学総合研究所, 生理活性物質研究部門, 研究員 Less
Review Section/Research Field	Principal Investigator 応用薬理学・医療系薬学 Except Principal Investigator Pediatrics / 物質生物化学 / Hematology
Keywords	Principal Investigator リソソーム / ファブリー病 / α-ガラクトシダーゼ / Lysosome / α-Galactosidase / 酵素補充療法 / Enzyme Replacement / Fadry Disease / α-ガラクトシターゼ / Enzyme replacement … More / Fabry disease / Transgenic Mouse / alpha-Galactosidase / Fabry Disease / トランスジェニック・マウス / Fabry病 … More Except Principal Investigator 遺伝子変異 / Bernard-Soulier syndrome / IX / protective protein / galactosialidosis / alpha-galactosidase / Fabry disease / 遺伝子解析 / ファブリー病 / 保護蛋白質 / ガラクトシアリドーシス / バキュロウイルス / α-ガラクトシダーゼ / epitope Deuterium labell / Fab fragment / hybridoma / Monoclonal antibody / alpha-Bungarotoxin / 核磁気共鳴 / ヘビ神経毒タンパク / α-ブンガロトキシン / エピトープ / Fab / 全重水素ラベル / 無血清培地化 / ハイブリドーマ / 単クローン抗体 / αーブンガロトキシン / Signal trunsduction / BSS Tokyo / V complex / GPlb / ristocetin-induced agglutination / ATP-release / 14-3-3 / GPlbalpha / BSS Tokyo II. / リストセチ凝集 / シグナル伝達 / BSS Tokyo II / V複合体 / GPIb / リストセチン凝集 / ATP放出 / 14-3-3ζ / GPIbα / GM2 activator / GM2 gangliosidosis / SSCP / サポシン / トランスジェニックマウス / アンチセンスオリゴDNA / X線結晶構造解析 / メタノール資化酵母 / GM2活性化蛋白質 / GM2ガングリオシドーシス / confocal laser scanning microscopy / enzyme replacement therapy / baculovirus / gene expression / 遺伝子大量発現 / αーガラクトシダ-ゼ / ファブリ-病 / レーザー走査型共焦点顕微鏡 / キメラ蛋白 / 先天代謝異常症 / alpha-ガラクトシダーゼ / 共焦点レーザー走査型顕微鏡 / 酵素補充療法 / フィブリー病 / 遺伝子発現 / β-ガラクトシドーシス / モルキオβ病 / GM_1ガングリオシドーシス / 表現型 / β-ガライトシダーゼ / 制限酵素部位解析 / モルキオB病 / G_<M1>ガングリオシド-シス / ライソゾ-ム病 / βーガラクトシグ-ゼ Less

Research Projects
(9 results)
Co-Researchers
(13 People)

Enzyme Replacement Therapy for Fabry Disease :Production of Efficient α-GalactosidasePrincipal Investigator
- Principal Investigator
  
  KASE Ryoichi
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
Studies of the enzyme replacement therapy for Fabry diseasePrincipal Investigator
- Principal Investigator
  
  KASE Ryoichi
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
Study on Outsode-in Signal Transduction via Platelet Membrane Glycoprotein lb
- Principal Investigator
  
  YAMAMOTO Naomasa
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  THE TOKYO METROPOLITAN INSTITUT OF MEDICAL SCIENCE
Developmental Studies of a Therapeutic Drug of Atypical Fabry Disease (Cardiac Form)Principal Investigator
- Principal Investigator
  
  KASE Ryoichi
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  the Tokyo Metropolitan Institute of Medical Science
Structural analysis and molecular designing of enzyme proteins : Its application to clarification of pathology of inherited metabolic diseases and development of therapy
- Principal Investigator
  
  SAKURABA Hitoshi
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  The Tokyo Metropolitan Institute of Medical Science
遺伝性ライソゾーム病における変異遺伝子発現機序の解析
- Principal Investigator
  
  鈴木義之
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
遺伝性ライソゾ-ム病における変異遺伝子発現機序の解析
- Principal Investigator
  
  鈴木義之
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
Gene expression and its application to the investigation on pathogenesis of congenital metabolic diseases and development of therapy for them.
- Principal Investigator
  
  SAKURABA Hitoshi
- Project Period (FY)
  1991 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  The Tokyo Metropolitan Institute of Medical Science
Molecular Recognition of Antigen Determinant by Monoclonal Antibody Specific to Neurotoxins from Snake Venoms
- Principal Investigator
  
  INAGAKI Fuyuhiko
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  物質生物化学
- Research Institution
  Tokyo Metropolitan Institute of Medical Science

1. SAKURABA Hitoshi (60114493)

# of Collaborated Projects: 7 results

# of Collaborated Products: 0 results
2. ITOH Kohji (00184656)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. ISHII Satoshi (00222935)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. OSHIMA Akihiro (20203763)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. SHIMMOTO Michie (20216237)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. 鈴木義之 (90010389)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. YAMAMOTO Naomasa (50150884)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. TANOUE Kenjiro (30014137)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. MATSUNO Kazuhiko (70102332)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. UTSUMI Kouichi (60291150)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. INAGAKI Fuyuhiko (70011757)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. KOHDA Daisuke (80186618)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. KITAGAWA Hisayo (70124451)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

KASE Ryoichi 加瀬 良一

KASE Ryouichi 加瀬 良一

Research Projects

Co-Researchers

Enzyme Replacement Therapy for Fabry Disease :Production of Efficient α-GalactosidasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies of the enzyme replacement therapy for Fabry diseasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study on Outsode-in Signal Transduction via Platelet Membrane Glycoprotein lb

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Developmental Studies of a Therapeutic Drug of Atypical Fabry Disease (Cardiac Form)Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Structural analysis and molecular designing of enzyme proteins : Its application to clarification of pathology of inherited metabolic diseases and development of therapy

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

遺伝性ライソゾーム病における変異遺伝子発現機序の解析

Principal Investigator

Project Period (FY)

Research Category

Research Institution

遺伝性ライソゾ-ム病における変異遺伝子発現機序の解析

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Gene expression and its application to the investigation on pathogenesis of congenital metabolic diseases and development of therapy for them.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular Recognition of Antigen Determinant by Monoclonal Antibody Specific to Neurotoxins from Snake Venoms

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

KASE Ryoichi 加瀬良一

KASE Ryouichi 加瀬良一