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TAGAWA MASATOSHI  田川 雅敏

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TAGAWA Masatoshi  田川 雅敏

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Researcher Number 20171572
Other IDs
Affiliation (Current) 2025: 千葉県がんセンター(研究所), がん治療開発グループ がん先進治療開発研究室, 客員研究員
Affiliation (based on the past Project Information) *help 2021 – 2023: 千葉大学, 大学院医学研究院, 特任教授
2019: 千葉県がんセンター(研究所), がん治療開発グループ, 特任研究員
2009 – 2018: Chiba Cancer Center (Research Institute), がん治療開発グループ, 部長
2015: 千葉県がんセンター研究所, 細胞治療開発研究部, 部長
2013: 千葉県がんセンター, 病理研究部, 部長 … More
2011: 千葉県がんセンター, がん治療開発グループ, 部長
2010: 千葉県がんセンター(研究所), がん研究開発グループ, 部長
2010: 千葉県がんセンター, 病理研究部, 部長
2008: 千葉県がんセンター, 病理研究部, 部長
2003 – 2008: 千葉県がんセンター(研究所), 病理研究部, 部長
2002 – 2007: CHIBA CANCER CENTER, RESEARCH INSTITUTE, DIVISION CHIEF, 研究局, 部長
1999 – 2003: 千葉県がんセンター, 病理研究部, 部長
2002: 千葉がんセンター, 病理研究部, 部長
1997 – 2000: 千葉県がんセンター, 研究局・病理研究部, 部長
1997 – 1998: 千葉県がんセンター, 研究局, 部長
1992 – 1996: 千葉大学, 医学部, 講師
1990: Chiba University, School of Medicine, Center for Neurobiology and Molecular Immu, 神経センター・国府台病院, 厚生技官
1987 – 1989: 千葉大学, 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
Digestive surgery / Digestive surgery / Basic Section 53030:Respiratory medicine-related / Biological Sciences
Except Principal Investigator
Orthopaedic surgery / Respiratory organ internal medicine / Gastroenterology / Immunology / Cerebral neurosurgery / Biological Sciences … More / Cerebral neurosurgery / Digestive surgery / Gastroenterology / Urology / Immunology / Pediatric surgery / Thoracic surgery / General surgery / Hygiene / 神経解剖学 Less
Keywords
Principal Investigator
遺伝子治療 / アデノウイルス / 遺伝子 / 食道がん / VEGF / ミッドカイン / Gene therapy / p53経路 / 細胞死 / 癌 … More / 細胞傷害活性 / 自殺遺伝子 / プロモーター / バイオテクノロジー / シグナル伝達 / MDM2 / MDM2分子 / FAK経路 / 遺伝子変異 / E1A / Mig / CD86 / IL-12 / CD40 / c-erbB-2 / レトロウイルス / 消化器がん / p53 / CP-31398 / 細胞障害活性 / CD46分子 / 遺伝子医薬 / CD46 / 腫瘍プロモーター / 間葉系幹細胞 / CD40リガンド / 転写活性 / 低酸素 / cytokine / サイトカイン / NFI / 細胞傷害 / アデノウィルス / FAK阻害剤 / MDM2阻害剤 / 悪性中皮腫 / 薬理学 / DNA傷害 / MDM4 / p21分子誘導 / FAK活性 / DNA障害 / Hippo経路 / Shuttle vector / Suvivin / Fiber region / Oncolytic adenovirus / E1B region / Transcriptional control region / Gastrointestival tumors / サバイビン / ファイバー・ノブ構造 / 腫瘍融解性ウイルス / シャトルベクター / サイバイビン / ファイバー領域 / 腫瘍融解性アデノウイルス / E1B領域 / 転写調節領域 / 消火器癌 / protective immunity / dendritic cells / CD40 ligand / 獲得免疫 / 樹状細胞 / Midkine / Transcriptional regulation / Suicide gene / Promoter / 転写調節 / エレクトロポレーション / c-erbB2 / 転写制御 / retrovirus / gene therapy / gastrointestinal cancer / helper T cells / tumor immunology / ヘルパーT細胞 / 腫瘍免疫 / 脱リン酸化 / pRb蛋白質 / p21分子 / 分子標的薬 / 細胞周期 / 食道癌 / p53 / 抗腫瘍効果 / 化学療法 / 受容体 / ウイルス / ウイルス受容体 / 初期応答遺伝子 / p53遺伝子 / コクサキーアデノウイルス受容体 / アポトーシス / 制限増殖型ウイルス / キャリアー細胞 / がん治療 / CAR / ファイバー・ノブ領域 / ウイルスデリバリー系 / 抗原提示 / Fasリガンド / TNF-alpha / NCX / 腫瘍細胞 / hematopoietic reconstitution / SCID-hu / Stem Cells / Gene Therapy / SCID … More
Except Principal Investigator
遺伝子治療 / gene therapy / アデノウイルス / アポトーシス / 腫瘍プロモーター / HSV-TK / brain tumor / サイトカイン / CD46 / 遺伝子 / Tumor promoter / Midkine / c-erbB-2 / ミッドカイン / glioma / 自殺遺伝子 / IL-12 / IL-2 / 悪性中皮腫 / CAR / 細胞死 / 抗がん剤 / 膵がん / 転写調節 / シグナル伝達 / リンパ球 / 免疫学 / BMP-2 / 培養脊柱靱帯細胞 / 脊柱靱帯骨化症 / E1 / NF-1 / immune therapy / vaccine / small G-proteins / E1A / 腫瘍融解性ウイルス / Gene Therapy / グリオーマ / Survivin / サバイビン / transcription factor / proliferation / lymphocyte / CD40 / 転写因子 / 遺伝子発現 / 増殖 / 免疫遺伝子治療 / TNF-α / 樹状細胞 / HSV-tk / 自殺遺伝子治療 / herpes simplex virus-thymidine kinase / ganciclovir / bystander effect / Transcriptional regulation / Gene therapy / IL-18 / IL-15 / サイトカイン遺伝子 / Brain Neoplasm / immunity / interleukin-2 / Rb蛋白 / p53経路 / アデノウイルスベクター / ペメトレキセド / 膀胱癌 / がん治療 / 突然変異 / 損傷乗り越えDNA合成 / bFGF / TGFβ1 / IGF-I / 成因 / 後縦靭帯骨化症 / 脊柱靭帯骨化症 / DNA結合蛋白 / バイオテクノロジー / トランスレーショナルリサーチ / ユビキチン化 / Mdm4 / Mdm2 / NF2 / MDM4 / AMPK-mTOR / 低分子G蛋白 / FAK / MDM2 / MDM2阻害剤 / 細胞障害活性 / Hippo経路 / 化学療法 / インシュリン様増殖因子 / 増殖因子 / 薬剤耐性 / 耐性 / ANKRD1 / AMPK / CARP / 薬物耐性 / Abelson murine leukemia virus / fatal thymus / hematopoietic cell differentiation / hematopoietic cell clones / B cell specific genes / mu chain complexes / Signal transduction / B cell differentiation / μ鎖複合体とシグナル伝達 / V遺伝子発現におけるプログラム / 胸腺由来未分化造血細胞株 / 胎生期胸腺内B前駆細胞 / 分化拘束 / 幼若造血細胞クロ-ン / μ鎖結合蛋白分子 / allelic exclusion / 細胞内シグナル伝達 / μ鎖複合体 / 幼若B細胞特異遺伝子 / 遺伝子再構成 / 造血幹細胞 / Bリンパ球分化・成熟 / Self reactive repertoire / TCRalpha-chain / Valpha14 TCR gene family / Homogenous TCR usage / T cell repertoire / Suppresser T cell receptor / キメラ・マウス / 内部抗原 / 抗原レセプター / Antiーsense RNA / V_α遺伝子ゲノム塩基配列 / 抑制T細胞レセプター / 免疫応答調節 / トランスジェニック・マウス / α鎖遺伝子 / 抑制T細胞リセプター / 免疫系ネットワ-ク / 分子生物学 / 胸腺非依存性の選択 / 自己反応性レパトア / 多様性欠除 / Vα14α鎖遺伝子 / 抑制T細胞 / proteomics / proteases / invasion / cathepsin D / 腫瘍マーカー / プロテオミクス / プロテアーゼ / 腫瘍浸潤 / カテプシンD / Pancreatic cancer / Adenovirus / 細胞受容体 / E3ファイバー領域 / シャトルベクター / ウイルス増殖 / CD45 / peptide / SCID mouse / Oncolytic virus / Transcription regulatory region / SCIDマウス / 転写調節領域 / apoptosis / differentiation / 分化 / cytokine / suicide gene / p53 gene / gastrointestinal cancer / in vivo electroporation / 消火器癌 / p53遺伝子 / 消化器癌 / in vivo電気穿孔法 / Interleukin-2 / neural progenitor cell / immune gene therapy / Cytokine / Glioma / GM-CSF / IL-4 / Neural Progenitor Cell / Antitamor Immunity / インターロイキン-2 / 神経前駆細胞 / Reporter assay / c-erb-B-2 / レポーターアッセイ / B cell antigen receptor / immune response / gene expression / B細胞抗原レセプター / 免疫応答 / SUCIDE GENE THERAPY / IMMUNOGENE THERAPY / NEUROBLASTOMA / 神経芽腫 / dendritic cells / antigen presentaion / lung metastasis / lung cancer / Fas ligand / CD40 ligand / 樹上細胞 / 抗原提示 / 肺転移 / 肺がん / Fasリガンド / CD40リガンド / COLON 26 / TH1 TYPE CYTOKINES / ADENORICUS VECTOR / DENDRITIC CELLS / Th1サイトカイン / Colon 26 / Colon26 / Th1タイプサイトカイン / アデノウィルスベクター / midkine / TUMOR SPECIFIC PROMOTER / SUICIDE GENE THERAPY / RREAST CANCER / c-erB2 / 腫瘍特異的プロモーター / c-erbB2 / 乳癌 / Suicide gene / Cyotokine / レトロウイルス / 転写制御 / Alcohol / MTHFR / Folic acid / Colorectal cancer / 葉酸代謝酵素(MTHFR) / 飲酒 / 大腸がん / Herpes Sumpley Virus-Thymidine Kinase / Major Histocoispastibility Complex / Antitumor Immumty / Gene Thetapy / immunoelectron microscopy / immunohistochemistry / postsynaptic density / monoclonal antibody / 82K protein / synaptophysin / synaptic vesicle / シナプス複合体 / 神経細胞 / シナプトフィシン / 82k蛋白 / 免疫電顕 / 免疫組織化学 / シナプス後部濃物質 / モノクロ-ナル抗体 / 82K蛋白 / シナプトファイシン / シナプス小胞 / メラノーマ関連遺伝子 / メラノーマ / ガン抗原 / ゲノムDNAクローニング / GM3-ラクトン / GM3 / メラノーマ抗原 / E1B / siRNA / ビスフォスフォネート / 抗腫瘍効果 / CD46蛋白質 / 腎臓癌 / Th17 / 血管新生因子 / 血管新生 / Th17 細胞 / 肺癌 / Geldanamycin / 塩酸ゲムシタビン / 細胞周期 / G2/M期 / アデノイルス / p53 / cytopathic effect / オートファジー / 遺伝子医薬 / 膵臓癌 / AdMKEla / バルプロ酸Na / 導入効率 / AdMKE1a / EIA遺伝子 / MDA-7 / インターロイキン24 / ファイバー・ノブ領域 / MDM-7 / E1A遺伝子 / 細胞傷害活性 / ウイルス / 膵臓がん / DNA修復 / 細胞がん化 / ノックアウトマウス / 発がん / DNAポリメラーゼζ / ファイブロネクチン / オステロネクチン / TGF-β1 / ALP活性 / BMP / TGF-β / 培養脊柱靭帯細胞 / 副甲状腺ホルモン(PTH) / アルカリフォスファターゼ / コラーゲン / twyマウス / 骨芽細胞 / 細胞培養 / 人工抗原 / Zn-finger構造 / 内在性抗原 / GM3結合蛋白 / メラノ-マ抗原 Less
  • Research Projects

    (54 results)
  • Research Products

    (212 results)
  • Co-Researchers

    (60 People)
  •  Molecular therapy of replication-competent adenoviruses targeting characteristic gene mutations found in mesotheliomaPrincipal Investigator

    • Principal Investigator
      TAGAWA Masatoshi
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53030:Respiratory medicine-related
    • Research Institution
      Chiba University
  •  Molecular therapy for esophageal cancer targeting the p53 and the Hippo pathwaysPrincipal Investigator

    • Principal Investigator
      TAGAWA Masatoshi
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Chiba Cancer Center (Research Institute)
  •  A therapeutic strategy for malignant mesothelioma with reconstituting tumor suppressor pathways which were defective due to the characteristic genetic deletion

    • Principal Investigator
      Shingyoji Masato
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Chiba Cancer Center (Research Institute)
  •  A novel cancer therapeutics with gene medicine and molecular targeted agents directing the p53 pathways in esophageal carcinomaPrincipal Investigator

    • Principal Investigator
      Tagawa Masatoshi
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Chiba Cancer Center (Research Institute)
  •  Development of targeted therapy to overcome drug resistance in malignant mesothelioma

    • Principal Investigator
      SEKINE Ikuo
    • Project Period (FY)
      2014 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      University of Tsukuba
      Chiba Cancer Center (Research Institute)
  •  Activation of the p53 pathway by gene medicine and a chemotherapeutic agent produces anti-tumor effects on human mesothelioma cells

    • Principal Investigator
      MASATO Shingyoji
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Chiba Cancer Center (Research Institute)
  •  Combinatory use of replication-competent adenoviruses and chemotherapeutic agents produces anti-tumor effects on human esophageal carcinoma cellsPrincipal Investigator

    • Principal Investigator
      TAGAWA Masatoshi
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Chiba Cancer Center (Research Institute)
  •  Development of new therapy using novel chimeric oncolytic adenoviruse vector for intractable bladder cancer.

    • Principal Investigator
      GOTOH Akinobu
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Hyogo Medical University
  •  INVOLVMENT OF TH17 CELLS IN TUMOR ANGIOGENESIS INDUCED BY INTERACION BETWEEN NON-SMALL CELL LUNG CANCER CELLS AND INTERSTITIAL STROMAL CELLS

    • Principal Investigator
      NUMASAKI Muneo
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Josai University
  •  Anti-tumor effects for solid tumors in digestive tracts were produced by a chimeric type of oncolytic adenoviruses and the carrier cells

    • Principal Investigator
      KAWAMURA Kiyoko
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Chiba Cancer Center (Research Institute)
  •  Mesenchymal stem cells infected with modified adenoviruses as carrier cells that target human gastrointestinal tumorsPrincipal Investigator

    • Principal Investigator
      TAGAWA Masatoshi
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Chiba Cancer Center (Research Institute)
  •  Conditionally Replicative Adenovirus for Targeting Bladder Cancer.

    • Principal Investigator
      TERAO Shuji
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Hyogo College of Medicine
  •  Therapeutic strategies with chimeric oncolytic adenoviruses and a cell-mediated delivery system for gastrointestinal solid tumors

    • Principal Investigator
      KAWAMURA Kiyoko
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Chiba Cancer Center (Research Institute)
  •  改変型細胞融解性ウイルスを搭載する間葉系幹細胞を用いた難治性消化器癌の治療Principal Investigator

    • Principal Investigator
      田川 雅敏
    • Project Period (FY)
      2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Chiba Cancer Center (Research Institute)
  •  Multifunctional therapeutic strategy for malignant gliomas targeting cathepsin D

    • Principal Investigator
      IWADATE Yasuo
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Chiba University
  •  Gene therapy for gastrointestinal tumors with adenovirus in which the fiber-knob region was replaced

    • Principal Investigator
      KAWAMURA Kiyoko
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Chiba Cancer Center Research Institute
  •  Oncolytic adenovirus modified to increase its infectivity for gastrointestinal cancerPrincipal Investigator

    • Principal Investigator
      TAGAWA Masatoshi
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Chiba Cancer Research Institute
  •  Development of glioma-specific peptide vaccine targeting small G-proteins

    • Principal Investigator
      IWADATE Yasuo
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Chiba University
  •  Role of novel genes expressed in activated B cells in the regulation of immune responses

    • Principal Investigator
      O-WANG Jiyang
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Immunology
    • Research Institution
      RIKEN
  •  Gene therapy for intractable gastrointestinal tumors with tumor promoter-mediated oncolyitc adenoviruses

    • Principal Investigator
      KAWAMURA Kiyoko
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Chiba Cancer Center Research Institute
  •  不忠実なDNAポリメラーゼ群の突然変異誘発及び発がん過程で果たす役割の解明

    • Principal Investigator
      王 継揚
    • Project Period (FY)
      2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Chiba Cancer Center (Research Institute)
  •  Development of multimodal gene therapy for gastrointestinal cancer using in vivo electroporation

    • Principal Investigator
      MATSUBARA Hisairo
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Digestive surgery
    • Research Institution
      Chiba University
  •  B細胞の抗体産生とアポトーシスを制御する新規遺伝子in vivoにおける機能

    • Principal Investigator
      王 継揚
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Chiba Cancer Center (Research Institute)
  •  Functional analysis of novel genes involved in the regulation of B cell activation and death

    • Principal Investigator
      OH Keiyou
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Immunology
    • Research Institution
      Chiba Cancer Center Research Institute
  •  Suicide gene therapy for intractable gastrointestinal cancer with tumor specific promoters

    • Principal Investigator
      KAWAMURA Kiyoko
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Chiba Cancer Center Research Institute
  •  Gene therapy for gastrointestinal tumors using antigen presenting cells activated with gene transferPrincipal Investigator

    • Principal Investigator
      TAGAWA Masatoshi
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Chiba Cancer Center Research Institute
  •  Cytokine gene therapy for brain tumors using neural progenitor cells

    • Principal Investigator
      IWADATE Yasuo
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Chiba University
  •  DNA複製エラーを惹起するDNAポリメラーゼ・ゼータが発がん過程で果たす役割

    • Principal Investigator
      OH Keiyou
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Chiba Cancer Center (Research Institute)
  •  遺伝子導入によって活性化された樹状細胞による抗原提示能の強化に基づいた抗腫瘍効果Principal Investigator

    • Principal Investigator
      田川 雅敏
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Chiba Cancer Center (Research Institute)
  •  SUICIDEAND IMMUNE GENE THERAPY USING TUMOR SPECIFIC PROMOTOR FOR BREAST CANCER

    • Principal Investigator
      MATSUBARA Hisahiro, 宮内 基博
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      CHIBA UNIVERSITY
      Chiba Cancer Center (Research Institute)
  •  THERAPEUTIC EFFECT OF DENDRITIC CELLS TRANSDUCED WITH TH1-TYPE-CYTOKINE-GENES BY RECOMBINANT ADENOVIRUS VECTOR ON GASTROINTESTINAL TUMOR GROWTH

    • Principal Investigator
      GUNJI Yoshio
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      CHIBA UNIVERSITY
  •  Forced expression of the TNF-family gene in lung cancer cells produced therapeutic effects, stimulating antigen-presentation processes.

    • Principal Investigator
      KOSHIKAWA Nobuko
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Thoracic surgery
    • Research Institution
      Chiba Cancer Center Research Institute
  •  GENE THERAPY FOR NEUROBLASTOMA

    • Principal Investigator
      YOSHIDA Hideo
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatric surgery
    • Research Institution
      CHIBA UNIVERSITY
  •  腫瘍で高発現を示す遺伝子のプロモーター領域を応用した自殺遺伝子治療Principal Investigator

    • Principal Investigator
      田川 雅敏
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Chiba Cancer Center (Research Institute)
  •  Therapeutic effects of cytokine gene therapy and suicide gene therapy for gastrointestinal tumors

    • Principal Investigator
      KAWAMURA Kiyoko
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Chiba Cancer Center Research Institute
  •  Suicide gene therapy for gastrointestinal tumors using tumor-specific promotersPrincipal Investigator

    • Principal Investigator
      TAGAWA Masatoshi
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Chiba Cancer Center Research Institute
  •  Bystander effect-mediated suicide gene therapy of experimental brain tumor by genetically engineered tumor cells in rat

    • Principal Investigator
      NAMBA Hiroki
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Hamamatsu University School of Medicine
  •  腫瘍において高発現をみる遺伝子のプロモーターを用いた自殺遺伝子治療の基礎的検討Principal Investigator

    • Principal Investigator
      田川 雅敏
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Chiba Cancer Center (Research Institute)
  •  アルコール代謝ならびに葉酸代謝酵素の遺伝的多型と大腸がんに関する疫学的研究

    • Principal Investigator
      MURATA Motoi
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hygiene
    • Research Institution
      Chiba Cancer Center Research Institute
  •  Immune gene therapy for gastrointestinal cancer by activation Th1-type helper T cells.Principal Investigator

    • Principal Investigator
      TAGAWA Masatoshi
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Chiba Cancer Center Research Institute
  •  Basic Research for The Immuno-genetherapy of Brain Tumors

    • Principal Investigator
      IWADATE Yasuo
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      CHIBA UNIVERSITY
  •  SCIDマウスを用いたサイトカイン遺伝子治療のin vivoモデルの確立Principal Investigator

    • Principal Investigator
      田川 雅敏
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Chiba University
  •  脊柱靱帯骨化症の発生に関与する骨増殖因子の解明と臨床応用のための基礎的研究

    • Principal Investigator
      後藤 澄雄
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Chiba University
  •  ヒト腫瘍細胞・TILを用いたサイトカイン遺伝子治療のin vivoモデルの確立Principal Investigator

    • Principal Investigator
      田川 雅敏
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Chiba University
  •  脊柱靱帯骨化症の発生に関与する骨増殖因子の解明と臨床応用のための基礎的研究

    • Principal Investigator
      後藤 澄雄
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Chiba University
  •  脊柱靱帯骨化症の発生に関与する骨増殖因子の解明と臨床応用のための基礎的研究

    • Principal Investigator
      後藤 澄雄
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Chiba University
  •  脊柱靭帯骨化症の発生に関与する骨増殖促進因子の解明と臨床応用のための基礎的研究

    • Principal Investigator
      後藤 澄雄
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Chiba University
  •  脊柱靭帯骨化症の発症に関与せる骨増殖促進因子の解明と臨床応用のための基礎的研究

    • Principal Investigator
      後藤 澄雄
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Chiba University
  •  Expression and localization of the synapse specific proteins in central nervous system of the postnatal rat.

    • Principal Investigator
      KADOTA Tomoko
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      神経解剖学
    • Research Institution
      Chiba University, School of Medicine
  •  腫瘍抗原の分子免疫学的研究

    • Principal Investigator
      谷口 克
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Chiba University
  •  Analysis of lymphoid cell differentiation

    • Principal Investigator
      TAKEMORI Toshitada
    • Project Period (FY)
      1988 – 1989
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Immunology
    • Research Institution
      National Institute of Health
      Chiba University
  •  腫瘍抗原の分子免疫学的研究

    • Principal Investigator
      TANIGUCHI Masaru
    • Project Period (FY)
      1987 – 1989
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Chiba University
  •  腫瘍抗原の分子免疫学的研究

    • Principal Investigator
      谷口 克
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Chiba University
  •  Molecualr mechanisms of cell-cell interactions and T cell repertoire formation.

    • Principal Investigator
      TANIGUCHI Masaru
    • Project Period (FY)
      1986 – 1989
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      Immunology
    • Research Institution
      Chiba University

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 Other

All Journal Article Presentation Book

  • [Book] 遺伝子治療開発研究ハンドブック2023

    • Author(s)
      田川雅敏
    • Total Pages
      722
    • Publisher
      (株)エヌ・ティー・エス
    • Data Source
      KAKENHI-PROJECT-21K08199
  • [Book] Mesotheliomas-synonyms and definition, epidemiology, etiology, pathogenesis, cyto-histopathological features, clinic, diagnosis, treatment, prognosis.2012

    • Author(s)
      Fukamachi, T., Saito, H., Tagawa, M. and Kobayashi, H.
    • Total Pages
      244
    • Publisher
      InTech
    • Data Source
      KAKENHI-PROJECT-23591951
  • [Book] Midkine: From embryogenesis to pathogenesis and therapy.2012

    • Author(s)
      Tagawa, M., Kawamura, K., Yu, L., Tada, Y., Hiroshima, K. and Shimada, H.
    • Total Pages
      319
    • Publisher
      Springer-Verlag Gmbh
    • Data Source
      KAKENHI-PROJECT-23591951
  • [Book] Type III interferon family-mediated anti-tumor responses through multiple mechanisms. In : Cellular and genetic practices for translational medicine. ed. by Jong-Young Kwak and Jin-Yeong Han2011

    • Author(s)
      Tagawa, M., Tada, Y., Hiroshima, K. and Shimada, H.
    • Publisher
      Research Signpost
    • Data Source
      KAKENHI-PROJECT-23591951
  • [Book] Cellular and genetic practices for translational medicine.2011

    • Author(s)
      Tagawa, M., その他
    • Total Pages
      260
    • Publisher
      Research Signpost
    • Data Source
      KAKENHI-PROJECT-23591951
  • [Book] Cancer Gene Therapy2010

    • Author(s)
      Masatoshi Tagawa
    • Total Pages
      249
    • Publisher
      Research Signpost
    • Data Source
      KAKENHI-PROJECT-20591585
  • [Book] Cancer Gene Therapy2010

    • Author(s)
      Tagawa, M.
    • Total Pages
      249
    • Publisher
      Research Signpost, Kerala, India.
    • Data Source
      KAKENHI-PROJECT-20591585
  • [Journal Article] An MDM2 inhibitor achieves synergistic cytotoxic effects with adenoviruses lacking E1B55kDa gene on mesothelioma with the wild-type p53 through augmenting NFI expression2021

    • Author(s)
      Nguyen, T.T.T., Shingyoji, M., Hanazono, M., Zhong, B., Morinaga, T., Tada, Y., Shimada, H., Hiroshima, K. and Tagawa, M.
    • Journal Title

      Cell Death Dis

      Volume: 12 Issue: 7 Pages: 663-663

    • DOI

      10.1038/s41419-021-03934-y

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K08199
  • [Journal Article] Cancer Cell-specific Transfection of hCas9 Gene Using Ad5F35 Vector2021

    • Author(s)
      MATSUNAGA WATARU、HAMADA KATSUYUKI、TAGAWA MASATOSHI、MORINAGA TAKAO、GOTOH AKINOBU
    • Journal Title

      Anticancer Research

      Volume: 41 Issue: 8 Pages: 3731-3740

    • DOI

      10.21873/anticanres.15164

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09681, KAKENHI-PROJECT-17K11279, KAKENHI-PROJECT-21K08199
  • [Journal Article] Combination of a p53-activating CP-31398 and an MDM2 or a FAK inhibitor produces growth suppressive effects in mesothelioma with wild-type p53 genotype.2020

    • Author(s)
      Zhong, B., Shingyoji, M., Hanazono, M., Nguye;n, T.T.T., Morinaga, T., Tada, Y., Hiroshima, K., Shimada, H. and Tagawa, M
    • Journal Title

      Apoptosis

      Volume: -

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K10617
  • [Journal Article] A p53-stabilizing agent, CP-31398, induces p21 expression with increased G2/M phase through the YY1 transcription factor in esophageal carcinoma defective of the p53 pathway.2019

    • Author(s)
      Zhong, B., Shingyoji, M., Hanazono, M., Nguyen, T.T.T., Morinaga, T., Tada, Y., Hiroshima, K., Shimada, H. and Tagawa, M.
    • Journal Title

      Am. J. Cancer Res.

      Volume: 9 Pages: 79-93

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K10617
  • [Journal Article] Heat shock protein 90 inhibitors augment endogenous wild-type p53 expression but down-regulate the adenovirally-induced expression by inhibiting a proteasome activity2018

    • Author(s)
      Chai Kuan、Ning Xuerao、Nguyen Thao Thi Thanh、Zhong Boya、Morinaga Takao、Li Zhihan、Shingyoji Masato、Tada Yuji、Tatsumi Koichiro、Shimada Hideaki、Hiroshima Kenzo、Yamaguchi Naoto、Tagawa Masatoshi
    • Journal Title

      Oncotarget

      Volume: 9 Issue: 40 Pages: 26130-26143

    • DOI

      10.18632/oncotarget.25452

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K10520, KAKENHI-PROJECT-16K09598
  • [Journal Article] An image cytometric technique is a concise method to detect adenoviruses and host cell proteins and to monitor the infection and cellular responses induced2017

    • Author(s)
      Morinaga Takao、Nguyen Thao Thi Thanh、Zhong Boya、Hanazono Michiko、Shingyoji Masato、Sekine Ikuo、Tada Yuji、Tatsumi Koichiro、Shimada Hideaki、Hiroshima Kenzo、Tagawa Masatoshi
    • Journal Title

      Virology Journal

      Volume: 14 Issue: 1 Pages: 219-219

    • DOI

      10.1186/s12985-017-0888-0

    • NAID

      120007128796

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K10617, KAKENHI-PROJECT-16K21639
  • [Journal Article] Cytotoxicity of replication-competent adenoviruses powered by an exogenous regulatory region is not linearly correlated with the viral infectivity/gene expression or with the E1A-activating ability but is associated with the p53 genotypes2017

    • Author(s)
      Yamauchi Suguru、Zhong Boya、Kawamura Kiyoko、Yang Shan、Kubo Shuji、Shingyoji Masato、Sekine Ikuo、Tada Yuji、Tatsumi Koichiro、Shimada Hideaki、Hiroshima Kenzo、Tagawa Masatoshi
    • Journal Title

      BMC Cancer

      Volume: 17 Issue: 1 Pages: 622-622

    • DOI

      10.1186/s12885-017-3621-x

    • NAID

      120007134865

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K10617
  • [Journal Article] Metformin produces growth inhibitory effects in combination with nutlin-3a on malignant mesothelioma through a cross-talk between mTOR and p53 pathways2017

    • Author(s)
      Shimazu Kengo、Tada Yuji、Morinaga Takao、Shingyoji Masato、Sekine Ikuo、Shimada Hideaki、Hiroshima Kenzo、Namiki Takao、Tatsumi Koichiro、Tagawa Masatoshi
    • Journal Title

      BMC Cancer

      Volume: 17 Issue: 1 Pages: 309-309

    • DOI

      10.1186/s12885-017-3300-y

    • NAID

      120007129116

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K09598
  • [Journal Article] Augmented expression of cardiac ankyrin repeat protein is induced by pemetrexed and a possible marker for the pemetrexed resistance in mesothelioma cells2017

    • Author(s)
      Qin Yiyang、Sekine Ikuo、Fan Mengmeng、Takiguchi Yuichi、Tada Yuji、Shingyoji Masato、Hanazono Michiko、Yamaguchi Naoto、Tagawa Masatoshi
    • Journal Title

      Cancer Cell International

      Volume: 17 Issue: 1 Pages: 120-120

    • DOI

      10.1186/s12935-017-0493-8

    • NAID

      120007134581

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K09598, KAKENHI-PROJECT-17K09647, KAKENHI-PROJECT-15K07922, KAKENHI-PROJECT-26461183
  • [Journal Article] A panel of autoantibodies against multiple tumor-associated antigens for detecting gastric cancer2017

    • Author(s)
      Hoshino, I., Nagata, M., Takiguchi, N., Nabeya, Y., Ikeda, A., Yokoi, S., Kuwajima, A., Tagawa, M., Matsushita, K., Yajima, S., Shimada, H.
    • Journal Title

      Cancer Sci

      Volume: 108 Issue: 3 Pages: 308-315

    • DOI

      10.1111/cas.13158

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26462000, KAKENHI-PROJECT-26462002, KAKENHI-PROJECT-15K10117, KAKENHI-PROJECT-16K10520, KAKENHI-PROJECT-26460951
  • [Journal Article] Combination of a third generation bisphosphonate and replication-competent adenoviruses augments the cytotoxicity on mesothelioma2016

    • Author(s)
      Jiang, Y., Zhong, B., Kawamura, K., Morinaga, T., Shingyoji, M., Sekine, I., Tada, Y., Tatsumi, K., Shimada, H., Hiroshima, K. and Tagawa, M.
    • Journal Title

      BMC Cancer

      Volume: 16 Issue: 1 Pages: 455-455

    • DOI

      10.1186/s12885-016-2483-y

    • NAID

      120007129538

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26462000, KAKENHI-PROJECT-16K09598, KAKENHI-PROJECT-26461183
  • [Journal Article] Clinical significance of serum autoantibodies against Ras-like GTPases, RalA, in patients with esophageal squamous cell carcinoma.2016

    • Author(s)
      Nanami, T., Shimada, H., Yajima, S., Oshima, Y., Matsushita, K., Nomura, F., Nagata, M., Tagawa, M., Otsuka, S., Kuwajima, A. and Kaneko, H
    • Journal Title

      Esophagus

      Volume: 13 Issue: 2 Pages: 167-172

    • DOI

      10.1007/s10388-015-0510-8

    • NAID

      40020807867

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26462000, KAKENHI-PROJECT-16K10519, KAKENHI-PROJECT-16K10520
  • [Journal Article] An intrapleural administration of zoledronic acid for inoperable malignant mesothelioma patients: a phase I clinical study protocol.2016

    • Author(s)
      Tada, Y., Hiroshima, K., Shimada, H., Shingyoji, M., Suzuki, T., Umezawa, H., Sekine, I., Takiguchi, Y., Tatsumi, K. and Tagawa, M.: An intrapleural administration of zoledronic acid for inoperable malignant mesothelioma patients: a phase I clinical study protocol
    • Journal Title

      SpringerPlus

      Volume: 5 Issue: 1 Pages: 195-202

    • DOI

      10.1186/s40064-016-1893-2

    • NAID

      120007129564

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26461183
  • [Journal Article] Molecular-targeted therapy for malignant mesothelioma2015

    • Author(s)
      Tada, Y., Suzuki, T., Shimada, H., Hiroshima, K., Tatsumi, K. and Tagawa, M
    • Journal Title

      Pleura

      Volume: 1 Pages: 1-11

    • DOI

      10.1177/2373997515600403

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26461183
  • [Journal Article] NY-ESO-1 autoantibody as a tumor-specific biomarker for esophageal cancer: screening in 1969 patients with various cancers2015

    • Author(s)
      Oshima Y, Shimada H, Yajima S, Nanami T, Matsushita K, Nomura F, Kainuma O, Takiguchi N, Soda H, Ueda T, Iizasa T, Yamamoto N, Yamamoto H, Nagata M, Yokoi S, Tagawa M, Ohtsuka S, Kuwajima A, Murakami A, Kaneko H
    • Journal Title

      J Gastroenterol

      Volume: Epub ahead of print Issue: 1 Pages: 30-34

    • DOI

      10.1007/s00535-015-1078-8

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24591961, KAKENHI-PROJECT-26462029, KAKENHI-PROJECT-26460951, KAKENHI-PROJECT-26462000
  • [Journal Article] A clinical protocol to inhibit the HGF/c-Met pathway for malignant mesothelioma with an intrapleural injection of adenoviruses expressing the NK4 gene.2015

    • Author(s)
      Tada, Y., Hiroshima, K., Shimada, H., Morishita, N., Shirakawa, T., Matsumoto, K., Shingyoji, M., Sekine, I., Tatsumi, K. and Tagawa, M.
    • Journal Title

      SpringerPlus

      Volume: 4 Issue: 1 Pages: 358-368

    • DOI

      10.1186/s40064-015-1123-3

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26461183, KAKENHI-PROJECT-15K14473
  • [Journal Article] Cytotoxic effects of replication-competent adenoviruses on human esophageal carcinoma are enhanced by forced p53 expression.2015

    • Author(s)
      Yang, S., Kawamura, K., Okamoto, S., Yamauchi, S., Shingyoji, M., Sekine, I., Kobayashi, H., Tada, Y., Tatsumi, K., Hiroshima, K., Shimada, H. and Tagawa, M.
    • Journal Title

      BMC Cancer

      Volume: 15 Issue: 1 Pages: 464-464

    • DOI

      10.1186/s12885-015-1482-8

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26462000
  • [Journal Article] Fas ligand DNA enhances a vaccination effect by coadministered DNA encoding a tumor antigen through augmenting production of antibody against the tumor antigen.2015

    • Author(s)
      Zhong, B., Ma, G., Sato, A., Shimozato, O., Liu, H., Li, Q., Shingyoji, M., Tada, Y., Tatsumi, K., Shimada, H., Hiroshima, K. and Tagawa, M.
    • Journal Title

      J Immunol Res

      Volume: 2015 Pages: 743828-743828

    • DOI

      10.1155/2015/743828

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24591185
  • [Journal Article] Zoledronic acid induces apoptosis and S-phase arrest in mesothelioma through inhibiting Rab family proteins and topoisomerase II actions.2014

    • Author(s)
      Okamoto, S., Jiang, Y., Kawamura, K., Shingyoji, M., Tada, Y., Sekine, I., Takiguchi, Y., Tatsumi, K., Kobayashi, H., Shimada, H., Hiroshima, K. and Tagawa, M.
    • Journal Title

      Cell Death Dis

      Volume: 5 Issue: 11 Pages: e1517-e1517

    • DOI

      10.1038/cddis.2014.475

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24591185, KAKENHI-PROJECT-26860622
  • [Journal Article] Mesenchymal stem cells are efficiently transduced with adenoviruses bearing type 35-derived fibers and the transduced cells with the IL-28A gene produces cytotoxicity to lung carcinoma cells co-cultured.2014

    • Author(s)
      Suzuki, T., Kawamura, K., Li, Q, Okamoto, S., Tada, Y., Tatsumi, K., Shimada, H., Hiroshima, K., Yamaguchi, N. and Tagawa, M.
    • Journal Title

      BMC Cancer

      Volume: 14 Pages: 713-713

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26462000
  • [Journal Article] Combination of adenoviruses expressing melanoma differentiation-associated gene-7 and chemotherapeutic agents produces enhanced cytotoxicity on esophageal carcinoma.2014

    • Author(s)
      Ma, G., Kawamura, K., Yang, S., Okamoto, S., Li, Q., Namba, M., Shingyoji, M., Tada, Y., Tatsumi, K., Hiroshima, K., Shimada, H. and Tagawa, M.
    • Journal Title

      Cancer Gene Ther.

      Volume: 21 Issue: 1 Pages: 31-37

    • DOI

      10.1038/cgt.2013.79

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591951, KAKENHI-PROJECT-26462000
  • [Journal Article] Enhanced antitumor efficacy of fiber-modified, midkine promoter-regulated oncolytic adenovirus in human malignant mesothelioma2013

    • Author(s)
      Takagi-Kimura, M., Yamano, T., Tamamoto, A., Okamura, N., Okamura, H., Hashimoto-Tamaoki, T., Tagawa, M., Kasahara, N. and Kubo, S.
    • Journal Title

      Cancer Sci.

      Volume: 104 Issue: 11 Pages: 1433-1439

    • DOI

      10.1111/cas.12267

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591951, KAKENHI-PROJECT-25460484
  • [Journal Article] Interferon-β Produces Synergistic Combinatory Anti-Tumor Effects with Cisplatin or Pemetrexed on Mesothelioma Cells.2013

    • Author(s)
      Li, Q., Kawamura, K., Yang, S., Okamoto, S., Kobayashi, H., Tada, Y., Sekine, I., Takiguchi, Y., Shingyouji, M., Tatsumi, K., Shimada, H., Hiroshima, K. and Tagawa, M.
    • Journal Title

      PloS one

      Volume: 8 Issue: 8 Pages: e72709-e72709

    • DOI

      10.1371/journal.pone.0072709

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591136, KAKENHI-PROJECT-24591185
  • [Journal Article] Heat-shock protein 90 inhibitors synergistically enhance melanoma differentiation-associated gene-7-mediated cell killing of human pancreatic carcinoma.2013

    • Author(s)
      Zhang, M., Kawamura, K., Jiang, Y., Shingyoji, M., Ma, G., Li, Q., Hu, J., Qi, Y., Liu, H., Zhang, F., Kang, S., Shan, B., Wang, S., Chada, S. and Tagawa, M.
    • Journal Title

      Cancer Gene Ther

      Volume: 20 Issue: 3 Pages: 663-670

    • DOI

      10.1038/cgt.2013.6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591185
  • [Journal Article] CD90 Is a Diagnostic Marker to Differentiate Between Malignant Pleural Mesothelioma and Lung Carcinoma With Immunohistochemistry.2013

    • Author(s)
      Kawamura, K., Hiroshima, K., Suzuki, T., Chai, K., Yamaguchi, N., Shingyoji, M., Yusa, T., Tada, Y., Takiguchi, Y., Tatsumi, K., Shimada, H. and Tagawa, M.
    • Journal Title

      Am. J. Clin. Pathol.

      Volume: 140 Issue: 4 Pages: 544-549

    • DOI

      10.1309/ajcpm2z4ngiipbge

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591136, KAKENHI-PROJECT-24591185
  • [Journal Article] Zoledronic acid produces combinatory anti-tumor effects with cisplatin on mesothelioma by increasing p53 expression levels.2013

    • Author(s)
      Okamoto, S., Jiang, Y., Kawamura, K., Shingyoji, M., Fukamachi, T., Tada, Y., Takiguchi, Y., Tatsumi, K., Shimada, H., Hiroshima, K., Kobayashi, H. and Tagawa, M.
    • Journal Title

      PLoS ONE

      Volume: 8 Issue: 3 Pages: e60297-e60297

    • DOI

      10.1371/journal.pone.0060297

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591185, KAKENHI-PROJECT-24591961
  • [Journal Article] Fiber-substituted conditionally replicating adenovirus Ad5F35 induces oncolysis of human bladder cancer cells in in vitro analysis.2013

    • Author(s)
      Gotoh A, Nagaya H, Kanno T, Tagawa M, Nishizaki T.
    • Journal Title

      Urology.

      Volume: 81 Issue: 4 Pages: 920.e7-920.e11

    • DOI

      10.1016/j.urology.2012.12.023

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591951, KAKENHI-PROJECT-23592354
  • [Journal Article] Gene therapy for malignant mesothelioma: Current prospects and challenges.2013

    • Author(s)
      Tagawa, M., Tada, Y., Shimada, H. and Hiroshima, K.
    • Journal Title

      Cancer Gene Ther.

      Volume: 20 Issue: 3 Pages: 150-156

    • DOI

      10.1038/cgt.2013.1

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591951
  • [Journal Article] Fiber-substituted conditionally replicating adenovirus Ad5F35 induces oncolysis of human bladder cancer cells in in vitro analysis2013

    • Author(s)
      Gotoh A, Nagaya H, Kanno T, Tagawa M, Nishizaki T
    • Journal Title

      Urology

      Volume: 81

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592354
  • [Journal Article] Zoledronic acid produces antitumor effects on mesothelioma through apoptosis and S-phase arrest in p53-independent and Ras prenylation-independent manners.2012

    • Author(s)
      Okamoto, S., Kawamura, K., Li, Q., Yamanaka, M., Yang, S., Fukamachi, T., Tada, Y., Tatsumi, T., Shimada, H., Hiroshima, K., Kobayashi, H. and Tagawa, M.
    • Journal Title

      J. Thorac. Oncol.

      Volume: 7 Issue: 5 Pages: 873-882

    • DOI

      10.1097/jto.0b013e31824c7d43

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591185, KAKENHI-PROJECT-24591961
  • [Journal Article] Upregulated p53 expression activates apoptotic pathways in wild-type p53-bearing mesothelioma and enhances cytotoxicity of cisplatin and pemetrexed2012

    • Author(s)
      Li, Q., Kawamura, K., Okamoto, S., Yamanaka, M., Yang, S., Yamauchi, S., Fukamachi, T., Kobayashi, H., Tada, Y., Takiguchi, Y., Tatsumi, K., Shimada, H., Hiroshima, K. and Tagawa, M.
    • Journal Title

      Cancer Gene Ther

      Volume: 19 Issue: 3 Pages: 218-228

    • DOI

      10.1038/cgt.2011.86

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590879, KAKENHI-PROJECT-22590850, KAKENHI-PROJECT-22591416, KAKENHI-PROJECT-23591136, KAKENHI-PROJECT-23591951, KAKENHI-PROJECT-24591185
  • [Journal Article] Fiber-substituted conditionally replicating adenovirus for oncolysis of human renal carcinoma cells2012

    • Author(s)
      Nagaya, H., Tagawa, M., Hiwasa, K., Terao, S., Kanno, T., Nishizaki, T. and Gotoh, A.
    • Journal Title

      Anticancer Res.

      Volume: 32 Pages: 2985-2990

    • URL

      http://ar.iiarjournals.org/content/32/7/2985.abstract

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591951
  • [Journal Article] Expression of a murine homolog of apoptosis-inducing human IL-24/MDA-7 in murine tumors fails to induce apoptosis or produce anti-tumor effects2012

    • Author(s)
      Nagakawa H, Shimozato O, 他9名
    • Journal Title

      Cellular Immunol

      Volume: 275 Issue: 1-2 Pages: 90-97

    • DOI

      10.1016/j.cellimm.2012.02.010

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790397, KAKENHI-PROJECT-23591951, KAKENHI-PROJECT-23591978, KAKENHI-PROJECT-24590496
  • [Journal Article] Antitumor effect of chondroitin sulfate-coated ternary granulocyte macro phage-colony-stimulating factor plasmid complex for ovarian cancer2012

    • Author(s)
      Katsuyuki Hamada, 他
    • Journal Title

      JOURNAL OF GENE MEDICINE

      Volume: 14 Issue: 2 Pages: 120-127

    • DOI

      10.1002/jgm.1647

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21500430, KAKENHI-PROJECT-23240133, KAKENHI-PROJECT-23591951, KAKENHI-PROJECT-23592453, KAKENHI-PROJECT-23700564
  • [Journal Article] Fiber-substituted conditionally replicating adenovirus for oncolysis of human renal carcinoma cells.2012

    • Author(s)
      Nagaya H, Tagawa M, Hiwasa K, Terao S, Kanno T, Nishizaki T Gotoh A.
    • Journal Title

      Anticancer Res

      Volume: 32 Pages: 2985-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592354
  • [Journal Article] E1B-55 kDa-defective adenoviruses activate p53 in mesothelioma and enhance cytotoxicity of anticancer agents2012

    • Author(s)
      Yamanaka, M, Tada, Y, Kawamura, K, Li, Q, Okamoto, S, Chai, K, Yokoi, S, Liang, M, Fukamachi, T, Kobayashi, H, Yamaguchi, N, Kitamura, A, Shimada, H, Hiroshima, K, Takiguchi, Y, et al.
    • Journal Title

      Journal Of Thoracic Oncology

      Volume: 7 Issue: 12 Pages: 1850-1857

    • DOI

      10.1097/jto.0b013e3182725fa4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591136, KAKENHI-PROJECT-24591185
  • [Journal Article] Fiber-substituted conditionally replicating adenovirus for oncolysis of human renal carcinoma cells.2012

    • Author(s)
      Nagaya, H., Tagawa, M., Hiwasa, K., Terao, S., Kanno, T., Nishizaki, T. and Gotoh, A.
    • Journal Title

      Anticancer Res.

      Volume: 32 Pages: 2985-2990

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591951
  • [Journal Article] Interaction and cross-resistance of cisplatin and pemetrexed in malignant pleural mesothelioma cell lines2012

    • Author(s)
      Kitazono-Saitoh M, Takiguchi Y, Sakaida E, Sekine I, Tanabe N, et al
    • Journal Title

      Oncology Reports

      Volume: 28(1) Pages: 33-40

    • DOI

      10.3892/or.2012.1799

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590850, KAKENHI-PROJECT-23591136, KAKENHI-PROJECT-24591185
  • [Journal Article] Impact of serum biomarkers on esophageal squamous cell carcinoma2012

    • Author(s)
      Shimada H, Yajima S, Oshima Y, Hiwasa T, Tagawa M, Matsushita K, Nomura F
    • Journal Title

      Esophagus

      Volume: 9(3) Issue: 3 Pages: 131-140

    • DOI

      10.1007/s10388-012-0332-x

    • NAID

      40019427695

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591416, KAKENHI-PROJECT-23591948, KAKENHI-PROJECT-23591951
  • [Journal Article] Antitumor activity of type III interferon alone or in combination with type I interferon against human non-small cell lung cancer2011

    • Author(s)
      Fujie H, Tanaka T, Tagawa M, Kaijun N, Watanabe M, Suzuki T, Nakayama K, Numasaki M
    • Journal Title

      Cancer Science

      Volume: 102 Pages: 1977-1990

    • NAID

      120005518441

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590869
  • [Journal Article] Antitumor activity of type III interferon alone or in combination with type I interferon against human non-small-cell lung cancer2011

    • Author(s)
      Fujie, H., Tanaka, T., Tagawa, M., Kaijun, N., Watanabe, M., Suzuki, T., Nakayama, K. and Numasaki, M.
    • Journal Title

      Cancer Sci.

      Volume: 102 Pages: 1977-1990

    • NAID

      120005518441

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591951
  • [Journal Article] Type III interferon alone or in combination with type I interferon inhibits the growth of human non-small cell lung cancer in vitro and in vivo.2011

    • Author(s)
      Hitomi Fujie, Toshiaki Tanaka, Saori Ishiyama, Masatoshi Tagawa, Katsutoshi Nakayama, Takashi Suzuki, Muneo Numasaki.
    • Journal Title

      Cancer Science

      Volume: (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590869
  • [Journal Article] A possible anti-cancer agent, type III interferon, activates cell death pathways and produces anti-tumor effects2011

    • Author(s)
      Tagawa, M., Kawamura, K., Li, Q., Tada, Y., Hiroshima, K. and Shimada, H.
    • Journal Title

      Clin. Dev. Immunol

      Volume: 2011 Pages: 1-6

    • DOI

      10.1155/2011/479013

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590879, KAKENHI-PROJECT-23591951
  • [Journal Article] Antitumor activity of type III interferon alone or in combination with type I interferon against human non-small cell lung cancer2011

    • Author(s)
      Fujie H、 Tanaka T、Tagawa M、 Kaijun N、 Watanabe M、 Suzuki T、 Nakayama K、 Numasaki M
    • Journal Title

      Cancer Sci

      Volume: 102 Issue: 11 Pages: 1977-1990

    • DOI

      10.1111/j.1349-7006.2011.02079.x

    • NAID

      120005518441

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590869, KAKENHI-PROJECT-23591951
  • [Journal Article] Adenoviruses-mediated transduction of human esophageal carcinoma cells with the interferon-lambda genes produced anti-tumor effects2011

    • Author(s)
      Li, Q., Kawamura, K., Okamoto, S., Fujie, H., Numasaki, M., Namba, M., Nagata, M., Shimada, H., Kobayashi, H. and Tagawa, M.
    • Journal Title

      Br. J. Cancer

      Volume: 105 Issue: 9 Pages: 1302-1312

    • DOI

      10.1038/bjc.2011.379

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590879, KAKENHI-PROJECT-22590869, KAKENHI-PROJECT-23591951
  • [Journal Article] A Distinct Regulatory Role of the Th17 Cytokines IL-17A and IL-17F in Chemokine Secretion from Lung Microvascular Endothelial Cells.2011

    • Author(s)
      Hitomi Fujie, Saori Ishiyama, Masatoshi Tagawa, Niu Kaijun, Haruki Kitazawa, Yoshihisa Tomioka, Muneo Numasaki.
    • Journal Title

      Inflammation

      Volume: (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590869
  • [Journal Article] Adenoviruses-mediated transduction of human oesophageal carcinoma cells with the interferon-1 genes produced anti-tumour effects2011

    • Author(s)
      Li Q, Kawamura K, Okamoto S, Fujie H, Numasaki M, Namba M, Nagata M, Shimada H, Kobayashi H, Tagawa M
    • Journal Title

      British Journal of Cancer

      Volume: 105 Pages: 1302-1312

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590869
  • [Journal Article] Interferon-λ induces G1 phase arrest or apoptosis in esophageal carcinoma cells and produces anti-tumor effects in combination with anti-cancer agents.2010

    • Author(s)
      Li Q., Kawamura K., Ma G., Iwata F., Numasaki M., Suzuki N., Shimada H., Tagawa M.
    • Journal Title

      Eur.J.Cancer 46

      Pages: 180-190

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591585
  • [Journal Article] Combinatory cytotoxic effects produced by E1B-55kDa-deleted adenoviruses and chemotherapeutic agents are dependent on the agents in esophageal carcinoma2010

    • Author(s)
      Ma, G., Kawamura, K., Li, Q., Okamoto, S., Suzuki, N., Kobayashi, H., Liang, M., Tada, Y., Tatsumi, K., Hiroshima, K., Shimada, H. and Tagawa, M.
    • Journal Title

      Cancer Gene Ther

      Volume: 17 Issue: 11 Pages: 803-813

    • DOI

      10.1038/cgt.2010.37

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590879
  • [Journal Article] Combinatory cytotoxic effects produced by E1B-55kDa-deleted adenoviruses and chemotherapeutic agents are dependent on the agents in esophageal carcinoma.2010

    • Author(s)
      Ma G., Kawamura K., Li Q., Okamoto S., Suzuki N., Kobayashi H., Liang M., Tada Y., Tatsumi K., Hiroshima K., Shimada H., Tagawa M.
    • Journal Title

      Cancer Gene Ther. 17

      Pages: 803-813

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591585
  • [Journal Article] Interferon-lambda induces G1 phase arrest or apoptosis in oesophageal carcinoma cells and produces anti-tumour effects in combination with anti-cancer agents2010

    • Author(s)
      Li Q、 Kawamura K、 Ma G、 Iwata F、 Numasaki M、 Suzuki N、 Shimada H、Tagawa M
    • Journal Title

      Eur. J. Cancer

      Volume: 46 Issue: 1 Pages: 180-190

    • DOI

      10.1016/j.ejca.2009.10.002

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590869
  • [Journal Article] Tumor specific low pH environment enhance the cytotoxicity of lovastatin and cantharidin2010

    • Author(s)
      Fukamachi, T., Chiba, Y., Wang, X., Saito, H., Tagawa, M. and Kobayashi, H.
    • Journal Title

      Cancer Lett

      Volume: 297 Issue: 2 Pages: 182-189

    • DOI

      10.1016/j.canlet.2010.05.010

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590879
  • [Journal Article] Cytotoxicity of adenoviruses expressing the wild-type p53 gene to esophageal carcinoma cells is linked with the CAR expression level and indirectly with the endogenous p53 status.2009

    • Author(s)
      Ma G., Kawamura K., Li Q., Suzuki N., Liang M., Namba M., Shimada H., Tagawa M.
    • Journal Title

      Cancer Gene Ther. 16

      Pages: 832-840

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591585
  • [Journal Article] Cytotoxicity of adenoviruses expressing the wild-type p53 gene to esophageal carcinoma cells is linked with the CAR expression level and indirectly with the endogenous p53 status2009

    • Author(s)
      Ma, G., Kawamura, K., Li, Q., Suzuki, N., Liang, M., Namba, M., Shimada, H. and Tagawa, M.
    • Journal Title

      Cancer Gene Ther

      Volume: 16 Issue: 11 Pages: 832-840

    • DOI

      10.1038/cgt.2009.21

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590879
  • [Journal Article] Cancer therapy with local oncolysis and topical cytokine secretion2008

    • Author(s)
      Tagawa, M., Kawamura, K., Ueyama, T., Nakamura, M., Tada, Y., Ma, G., Li, Q., Suzuki, N., Shimada, H., Kuriyama, T. and Ochiai, T
    • Journal Title

      Front. Biosci 13

      Pages: 2578-2587

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590798
  • [Journal Article] IL-27-mediated activation of natural killer cells and inflammation produced antitumor effects for human oesophageal carcinoma cells.2008

    • Author(s)
      Liu L., Wang S., Shan B., Shao L., Sato A., Kawamura K., Li Q., Ma G., Tagawa M.
    • Journal Title

      Scand.J.Immunol. 68

      Pages: 22-29

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591585
  • [Journal Article] Adenovirus type 5 substituted with type 11 or type 35 fiber structure increases its infectivity to huma cells and enable dualgene transfer in CD46-dependent and -independent manners2007

    • Author(s)
      Yu, L., Shimozato, O., Li, Q., Kawamura, K., Ma, G., Namba, M., Ogawa, T., Kaiho, I. And Tagawa, M
    • Journal Title

      Antican

    • Data Source
      KAKENHI-PROJECT-19590798
  • [Journal Article] Transcriptional regulatory regions of the survivin gene activate an exogenous suicide gene in human tumors and enhance the sensitivity to a prodrug2007

    • Author(s)
      Kawamura, K., Yu, L., Tomizawa, M., Shimozato, O., Ma, G., Li, Q., Sato, A., Yang, Y., Suzuki, T., Abdel-Azizi, N. M., Tagawa, M
    • Journal Title

      Anticancer Res 27

      Pages: 89-94

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590798
  • [Journal Article] The effects of FasL on inflammation and tumor survival are dependent on its2007

    • Author(s)
      Wada A., Tada Y, Kawamura K., Takiguchi Y, Tatsumi K., Kuriyama T., Takenouchi T., O-Wang J., Tagawa M.
    • Journal Title

      Cancer Gene Ther.

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590692
  • [Journal Article] Transcriptional regulatory regions of the survivin gene activate an exogenous suicide gene human tumors and enhance the sensitivity to a prodrug.2007

    • Author(s)
      Kawamura K., Yu L., Tomizawa M., Shimozato 0., Ma G., Li Q., Sato A., Yang Y., Suzuki T., Abdel-Azizi N.M., Tagawa M.
    • Journal Title

      Anticancer Res.

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590692
  • [Journal Article] Virology- and immunology-based gene therapy for cancer.2006

    • Author(s)
      Tagawa, Masatoshi
    • Journal Title

      Cancer Immunol.Immunother. 55

      Pages: 1420-1425

    • Data Source
      KAKENHI-PROJECT-18591493
  • [Journal Article] Role of DNA polymerase θ in tolerance of endogenous and exogenous DNA damage in mouse B cells.2006

    • Author(s)
      Ukai A., Maruyama T., Mochizuki S., Ouchida R., Masuda K., Kawamura K., Tagawa M., Kinoshita K., Sakamoto A., Tokuhisa T., O-Wang J.
    • Journal Title

      Genes to Cells

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590692
  • [Journal Article] Virology-and immunology-based gene therapy for cancer.2006

    • Author(s)
      Tagawa M., Kawamura K., Shimozato 0., Ma G., Li Q., Suzuki N., Shimada H., Ochiai T.
    • Journal Title

      Cancer Immunol. Immunother.

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590692
  • [Journal Article] Up-regulated expression of the uridine phosphorylase gene in human gastric tumors is correlated with a favorable prognosis.2006

    • Author(s)
      Kawamura K., Takiguchi N., Wada A., Takenobu H., Kimura H., Soda H., Nagata M., Asano T., Tagawa M
    • Journal Title

      Anticancer Res.

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590692
  • [Journal Article] Virology-and immunology-based gene therapy for cancer2006

    • Author(s)
      Tagawa, M
    • Journal Title

      Anticancer Res. 55

      Pages: 1420-1425

    • Data Source
      KAKENHI-PROJECT-17590692
  • [Journal Article] Virology- and immunology-based gene therapy for cancer.2006

    • Author(s)
      Tagawa, M
    • Journal Title

      Cancer Immunol. Immunother. 55

      Pages: 1420-1425

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590692
  • [Journal Article] Increased infectivity of adenovirus type 5 bearing type 11 or type 35 fibers to human esophageal and oral carcinoma cells.2005

    • Author(s)
      Yu, L., Takenobu, H., Shimozato, O., Kawamura, K., Nimura, Y., Seki, N., Ugai, K., Tanzawa, H., Shimada, H., Ochiai, T., Tagawa, M
    • Journal Title

      Oncol.Rep. 14

      Pages: 831-835

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591381
  • [Journal Article] Expression of the fetal-oncogenic fibroblast growth factor-8/17/18 subfamily in human hematopoietic tumors.2005

    • Author(s)
      Nezu, M., Tomonaga, T., Sakai, C., Ishii, A., Itoga, S., Nishimura, M., Matsuo, Y., Tagawa, M., Nomura, F.
    • Journal Title

      Biochem.Biophys.Res.Commun. 335

      Pages: 843-849

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591381
  • [Journal Article] recombinant Sendai virus vector indeces complete remission of established brain tumors trough efficient interleukin-2 gene transfer in vaccinated rats.2005

    • Author(s)
      Iwadata Y, Tagawa M etal.
    • Journal Title

      Clin. Cancer Res. 11

      Pages: 3821-3827

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16591381
  • [Journal Article] Increased infectivity of adenovirus type 5 bearing type 11 or type 35 fibers to human esophageal and oral carcinoma cells.2005

    • Author(s)
      Yu L, Tagawa M et al.
    • Journal Title

      Oncol.Rep. 14

      Pages: 831-835

    • Data Source
      KAKENHI-PROJECT-16591381
  • [Journal Article] Expression of IL-27 in murine carcinoma cells produces antitumor effects and induces protective immunity in inoculated host animals.2005

    • Author(s)
      Chiyo M, Tagawa M et al.
    • Journal Title

      Int. J Cancer 115

      Pages: 437-442

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16591381
  • [Journal Article] Up-regulation of the error-prone DNA polymerase x promotes pleiotropic genetic- alterations and tumorigenesis.2005

    • Author(s)
      Bavoux, C., Leopoldino, A.M., Bergoglio, V., O-Wang, J., Ogi, T., Bieth, A., Pena, S.D.J., Poupon, M., Helleday, T., Tagawa, M., Machado, C.R., Hoffmann, J., Cazaux, C.
    • Journal Title

      Cancer Res. 65

      Pages: 325-330

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591381
  • [Journal Article] Recombinant Sendai virus vector induces complete remission of established brain tumors through efficient interleukin-2 gene transfer in vaccinated rats.2005

    • Author(s)
      Iwadate Y, Tagawa M et al.
    • Journal Title

      Clin.Cancer Res. 11

      Pages: 3821-3827

    • Data Source
      KAKENHI-PROJECT-16591381
  • [Journal Article] Increased infectivity of adenovirus type 5 bearing type 11 or type 35 fibers to human esophageal and oral carcinoma cells.2005

    • Author(s)
      Yu L, Tagawa M et al.
    • Journal Title

      Oncol,Rep. 14

      Pages: 831-835

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16591381
  • [Journal Article] Expression of IL-27 in murine carcinoma cells produces antitumor effects and induces protective immunity in inoculated host animals.2005

    • Author(s)
      Chiyo, M., Shimozato, O., Yu, L., Kawamura, K., Iizasa, T., Fujisawa, T., Tagawa, M.
    • Journal Title

      Int.J.Cancer 115

      Pages: 437-442

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591381
  • [Journal Article] Up-regulation of the error-prone DNA polymerase K promotes pleiotropic genetic alterations and tumorigenesis.2005

    • Author(s)
      Bavoux C, Tagawa M et al.
    • Journal Title

      Cancer Res. 65

      Pages: 325-330

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16591381
  • [Journal Article] Expression of the fetal-oncogenic fibroblast groeth factor-8/17/18 subfamily in human hematopoietic tumors.2005

    • Author(s)
      Nezu M, Tagawa M et al.
    • Journal Title

      Biochem. Biophys. Res. Commun. 335

      Pages: 843-849

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16591381
  • [Journal Article] Up-regulation of the error-prone DNA polymerase κ promotes pleiotropic genetic alterations and tumorigenesis.2005

    • Author(s)
      Bavoux C, Tagawa M et al.
    • Journal Title

      Cancer Res. 65

      Pages: 325-330

    • Data Source
      KAKENHI-PROJECT-16591381
  • [Journal Article] Vaccination of apoptotic Fas ligand-expressing tumors decreased antitumor responses by enhanced production of immunosuppressive cytokines.2005

    • Author(s)
      Wada, A., Tada, Y., Shimozato, 0., Takiguchi, Y., Tatsumi, K., Kuriyama, T., Tagawa, M.
    • Journal Title

      Anticancer Res. 25

      Pages: 299-304

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591381
  • [Journal Article] Recombinant Sendai virus vector induces complete remission of established brain tumors through efficient interleukin -2 gene transfer in vaccinated rats.2005

    • Author(s)
      Iwadate, Y., Inoue, M., Saegusa, T., Tokusumi, Y., Kinoh, H., Hasegawa, M., Tagawa, M., Yamaura, A., Shimada, H.
    • Journal Title

      Clin.Cancer Res. 11

      Pages: 3821-3827

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591381
  • [Journal Article] Vaccination of apoptotic Fas ligand-expressing tumors decreased antitumor responses by enhanced production of immunosuppressive cytokines.2005

    • Author(s)
      Wada A, Tagawa M et al.
    • Journal Title

      Anticancer Res. 25

      Pages: 299-304

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16591381
  • [Journal Article] Increased infectivity of adenovirus type 5 bearing type 11 or type 35 fibers to human esophageal and oral carcinoma cells.2005

    • Author(s)
      Yu L., Takenobu H., Shimozato 0., Kawamura K., Nimura Y., Seki N., Uzawa K., Tanzawa H., Shimada H., Ochiai T., Tagawa M.
    • Journal Title

      Oncol. Rep.

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590692
  • [Journal Article] Vaccination of apoptotic Fas ligand-expressing tumors decreased antitumor responses by enhanced production of immunosuppressive cytokines.2005

    • Author(s)
      Wada A, Tagawa M et al.
    • Journal Title

      Anticancer Res 25

      Pages: 299-304

    • Data Source
      KAKENHI-PROJECT-16591381
  • [Journal Article] Expression of the fetal-oncogenic fibroblast growth factor-8/17/18 subfamily in human hematopoietic tumors.2005

    • Author(s)
      Nezu M, Tagawa M et al.
    • Journal Title

      Biochem.Biophys.Res.Commun 333

      Pages: 843-849

    • Data Source
      KAKENHI-PROJECT-16591381
  • [Journal Article] Expression of IL-27 in murine carcinoma cells produces antitumor effects and induces protective immunity in inoculated host animals.2005

    • Author(s)
      Chiyo M, Tagawa M et al.
    • Journal Title

      Int.J.Cancer 115

      Pages: 437-442

    • Data Source
      KAKENHI-PROJECT-16591381
  • [Journal Article] The secretion form of the p40 subunit of interleukin (IL)-12 inhibits IL-23 functions and abrogates IL-23-mediated antitumor effects.2005

    • Author(s)
      Shimozato O., Ugai S., Chiyo M., Takenobu H., Nagakawa H., Wada A., Kawa mura K., Yamamoto H., Tagawa, M.
    • Journal Title

      Immunology

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590692
  • [Journal Article] Expression of IL-27 in murine carcinoma cells produces antitumor effects and induces protective immunity in inoculated host animals.2005

    • Author(s)
      Chiyo M., Shimozato 0., Yu L., Kawamura K., Iizasa T., Fujisawa T., Tagawa M.
    • Journal Title

      Int. J. Cancer

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590692
  • [Journal Article] DNA polymerase θ contributes to the generation of C/G mutations during somatic hypermutation of Ig genes.2005

    • Author(s)
      Masuda K., Ouchida R., Takeuchi A., Saito T., Koseki H., Kawamura K., Tagawa M., Tokuhisa T., Azuma T., O-Wang J.
    • Journal Title

      Proc. Natl. Acad. Sci. USA

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590692
  • [Journal Article] Expression of interleukin-22 in murine carcinoma cells did not influence tumor growth in vivo but did improve the survival of inoculated hosts.2004

    • Author(s)
      Nagakawa, H., Shimozato, O., Yu, L., Takiguchi, Y., Tatsumi, K., Kuriyama, T., Tagawa, M.
    • Journal Title

      Scand.J.Immunol. 60

      Pages: 449-454

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591381
  • [Journal Article] Midkine promoter can mediate transcriptional activation of a fused suicide gene in a broader range of human breast cancer compared with c-erbB-2 promoter.2004

    • Author(s)
      Yu, L., Yamamoto, N., Kadomatsu, K., Muramatsu, T., Matsubara, S., Sakiyama S., Tagawa, M.
    • Journal Title

      Oncology 66

      Pages: 143-146

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590706
  • [Journal Article] Midkine promoter-driven suicide gene expression and -mediated adenovirus replication produced cytotoxic effects to immortalized and tumour cells.2004

    • Author(s)
      Yu, L., Hamada, K., Namba, M., Kadomatsu, K., Muramatsu, T., Matsubara, S., Tagawa, M.
    • Journal Title

      Eur.J.Cancer 40

      Pages: 1787-1794

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591381
  • [Journal Article] Insertion of an exogenous promoter in the E1A regulatory region of adenovirus does not disturb viral replication despite reduced E1A transcription.2004

    • Author(s)
      Yu, L., Hamada, K., Namba, M., Kadomatsu, K., Muramatsu, T., Matsubara, S., Tagawa, M.
    • Journal Title

      Cancer Lett. 203

      Pages: 51-57

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591381
  • [Journal Article] Antitumor effects produced by tranduction of dendritic cells-derived heterodimeric cytokine genes in murne colon carcinoma cells.2004

    • Author(s)
      Chiyo M, Tagawa M et al.
    • Journal Title

      Anticancer Res. 24

      Pages: 3763-3768

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16591381
  • [Journal Article] Expression of interleukin-21 and -23 in human esphageal tumors produced antitumor sffects in nude mice.2004

    • Author(s)
      Shan B, Tagawa M et al.
    • Journal Title

      Anticaner Res. 24

      Pages: 79-82

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16591381
  • [Journal Article] A Cox-2 promoter-based replication-selective adenovital vector to target the Cox-2-expressing human bladder cancer cells.2004

    • Author(s)
      shirakawa T, Tagawa M et al.
    • Journal Title

      Clin. Cancer Res. 10

      Pages: 4342-4348

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16591381
  • [Journal Article] Insertion of an exogenous promoter in the E1A regulatory region of adenovirus does not disturb viral replication despite reduced E1 A transcription.2004

    • Author(s)
      Yu, L., Hamada, K., Namba, M., Kadomatsu, K., Muramatsu, T., Matsubara, S., Tagawa, M.
    • Journal Title

      Cancer Lett. 203

      Pages: 51-57

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590706
  • [Journal Article] DNA polymerase θ is preferentially expressed in lymphoid tissues and upregulated in human cancers.2004

    • Author(s)
      Kawamura, K., Bahar, R., Seimiya, M., Chiyo, M., Wada, A., Okada, S., Hatano, M., Tokuhisa, T., Kimura, H., Watanabe, S., Honda, I., Sakiyama, S., Tagawa, M., O-Wang, J.
    • Journal Title

      Int.J.Cancer 109

      Pages: 9-16

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590706
  • [Journal Article] Insertion of an exogenous progenous promoter in the E1A regulatory of adenovirus dose not disturb viral replication despote reduced E1A transcription.2004

    • Author(s)
      Yu L, Tagawa M et al.
    • Journal Title

      Cancer Lett. 203

      Pages: 51-57

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16591381
  • [Journal Article] Midkine promoter can mediate transcriptional activation of a fused suicide gene in a broader range of human breast cancer compared with c-erbB-2 promoter.2004

    • Author(s)
      Yu, L., Yamamoto, N., Kadomatsu, K., Muramatsu, T., Matsubara, S., Sakiyama S., Tagawa, M.
    • Journal Title

      Oncology 66

      Pages: 143-146

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591381
  • [Journal Article] Expression of interleukin-21 and -23 in human esophageal tumors produced antitumor effects in nude mice.2004

    • Author(s)
      Shan, B., Yu, L., Shimozato, O., Li, Q., Tagawa, M.
    • Journal Title

      Anticancer Res. 24

      Pages: 79-82

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591381
  • [Journal Article] Midkine promoter-based conditinally replicative adenovirus for malignant glioma the rapy.2004

    • Author(s)
      Kohno S, Tagawa M et al.
    • Journal Title

      Oncol Rep. 12

      Pages: 73-78

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16591381
  • [Journal Article] Midkine promoter-driven suicide gene expression and -mediated adenovirus replication produced cytotoxic effects to immortalizad and tumour calls2004

    • Author(s)
      Yu L, Tagawa M et al.
    • Journal Title

      Eur.J.Cancer 40

      Pages: 1787-1794

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16591381
  • [Journal Article] Midkine promoter-based conditionally replicative adenovirus for malignant glioma therapy.2004

    • Author(s)
      Kohno, S., Nakagawa, K., Hamada, K., Harada, H., Yamasaki, K., Hashimoto, K., Tagawa, M., Nagato, S., Furukawa, K., Ohnishi, T.
    • Journal Title

      Oncol Rep. 12

      Pages: 73-78

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591381
  • [Journal Article] Expression of interleukin-22 in murine carcinoma cells did not influence tumor groeth in vivo but did improve the survival of inoculated hosts.2004

    • Author(s)
      Nagakawa H, Tagawa M et al.
    • Journal Title

      Scand. J. Immunol. 60

      Pages: 449-454

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16591381
  • [Journal Article] Antitumor effects produced by tranduction of dendritic cells-derived heterodimeric cytokine genes in murine colon carcinoma cells.2004

    • Author(s)
      Chiyo, M., Shimozato, O., Iizasa, T., Fujisawa, T., Tagawa, M.
    • Journal Title

      Anticancer Res. 24

      Pages: 3763-3768

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591381
  • [Journal Article] Expression of the interleukin-21 and -23 in human esophageal tumors Produced antitumor effects in nude mice.2004

    • Author(s)
      Shan B., Yu L., Shimozato O., Li Q., Tagawa M.
    • Journal Title

      Anticancer Res 24

      Pages: 79-82

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370377
  • [Journal Article] Expression of the interleukin-21 and -23 in human esophageal tumors produced Antitumor effects in nude mice.2004

    • Author(s)
      Shan B., Yu L., Shimozato O., Li Q., Tagawa M.
    • Journal Title

      Anticancer Res 24

      Pages: 79-82

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14370377
  • [Journal Article] A Cox-2 promoter-based replication-selective adenoviral vector to target the Cox-2-expressing human bladder cancer cells.2004

    • Author(s)
      Shirakawa, T., Hamada, K., Zhang, Z., Okada, H., Tagawa, M., Kamidono, S., Kawabata, M., Gotoh, A.
    • Journal Title

      Cancer Res. 10

      Pages: 4342-4348

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591381
  • [Journal Article] Expression of CD40 ligand in CD40-positive murine tumors activates transcription of the interleukin-23 subunit genes and produces antitumor responses.2004

    • Author(s)
      Wada, A., Tada, Y., Shimozato, O., Takiguchi, Y., Tatsumi, K., Kuriyama, T., Tagawa, M.
    • Journal Title

      Anticancer Res. 24

      Pages: 2713-2716

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590706
  • [Journal Article] Elevated expression of DNA polymerase x expression in human lung cancer is associated with p53 inactivation: Negative regulation of POLKpromoter activity by p53.2004

    • Author(s)
      Wang, Y.Q., Seimiya, M., Kawamura, K., Yu, L., Ogi, T., Takenaga, K., Shishikura, T., Nakagawara, A., Sakiyama, S., Tagawa, M., O-Wang, J.
    • Journal Title

      Int.J.Oncol. 25

      Pages: 161-165

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591381
  • [Journal Article] Midkine promoter-driven suicide gene expression and-mediated adenovirus replication produced cytotoxic effects to immortalized and tumour cells.2004

    • Author(s)
      Yu, L., Hamada, K., Namba, M., Kadomatsu, K., Muramatsu, T., Matsubara, S., Tagawa, M.
    • Journal Title

      Eur.J.Cancer 40

      Pages: 1787-1794

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590706
  • [Journal Article] Impaired lymphocyte development and function in Clast5/Stra13/DEC1 transgenic mice.2004

    • Author(s)
      Seimiya, M., Wada, A., Kawamura, K., Sakamoto, A., Ohkubo, Y., Okada, S., Hatano, M., Tokuhisa, T., Watanabe, T., Saisho, H., Tagawa, M., O-Wang, J.
    • Journal Title

      Eur.J.Immunol. 34

      Pages: 1322-1332

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591381
  • [Journal Article] Midkine promoter can mediate transcriptional activation of a fused suicide gene in a broader range of human breast cancer compared with c-erdB-2 promoter.2004

    • Author(s)
      Yu L, Tagawa M et al.
    • Journal Title

      Oncology 66

      Pages: 143-146

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16591381
  • [Journal Article] Correlation between interleukin 6 production and tumor proliferation in non-small cell lung cancer.2004

    • Author(s)
      Yamaji, H., Iizasa, T., Koh, E., Suzuki, M., Otsuji, M., Chang, H., Motohashi, S., Yokoi, S., Hiroshima, K., Tagawa, M., Nakayama, T., Fujisawa T.
    • Journal Title

      Cancer Immunol.Immunother. 53

      Pages: 786-792

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591381
  • [Journal Article] Elevated expression of DNA polymerase κ expression in human lung cancer is associated with p53 inactivation : Negative regulation of POLK promoter activity by p53.2004

    • Author(s)
      Wang, Y.Q., Seimiya, M., Kawamura, K., Yu, L., Ogi, T., Takenaga, K., Shishikura, T., Nakagawara, A., Sakiyama, S., Tagawa, M., O-Wang, J.
    • Journal Title

      Int.J.Oncol. 25

      Pages: 161-165

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590706
  • [Journal Article] Correlation between interleukin 6 production and tumor proliferation in non-small cell ling2004

    • Author(s)
      Yamaji H, Tagawa M et al.
    • Journal Title

      Cancer Immunol. Immunother. 53

      Pages: 786-792

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16591381
  • [Journal Article] Expression of the interleukin-21 gene in murine colon carcinoma cells generates systemic immunity in the inoculated hosts.2003

    • Author(s)
      Ugai S, Shimozato O, Kawamura K, Wang YQ, Yamaguchi T, Saisho H, Sakiyama S., Tagawa M.
    • Journal Title

      Cancer Gene Ther. 10

      Pages: 187-192

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370377
  • [Journal Article] Regulatory regions of growth-related genes can activate an exogenous gene of the α-fetoprotein promoter to a comparable degree in human hepatocellular carcinoma cells.2003

    • Author(s)
      Tomizawa, M., Saisho, H., Tagawa, M.
    • Journal Title

      Anticancer Res. 23

      Pages: 3273-3277

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590706
  • [Journal Article] Fas ligand-expressing tumors induce tumor-specific protective mmunity in the inoculated hosts but vaccination with the apoptotic tumors suppresses antitumor immunity.2003

    • Author(s)
      Tada, Y., O-Wang, J., Wada, A., Takiguchi, Y., Tatsumi, K., Kuriyama, T., Sakiyama, S., Tagawa, M.
    • Journal Title

      Cancer Gene Ther. 10

      Pages: 134-140

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590706
  • [Journal Article] Preoperative serum midkine concentration is a prognostic marker for esophageal squamous cell carcinoma.2003

    • Author(s)
      Shimada H, Nabeya Y, Tagawa M, Okazumi S, Matsubara H, Ochiai T., et al.
    • Journal Title

      Cancer Sci. 94・7

      Pages: 628-632

    • NAID

      10011688973

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14370377
  • [Journal Article] Cell growth- and P53-dependent transcriptional activity of the midkine promoter confers suicide gene expression in tumor cells.2003

    • Author(s)
      Yu, L., Ugai, S., O-Wang, J., Namba, M., Kadomatsu, K., Muramatsu, T., Matsubara, S., Sakiyama, S., Tagawa, M.
    • Journal Title

      Oncol.Rep. 10

      Pages: 1301-1305

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590706
  • [Journal Article] Expression of the interleukin-21 gene in murine colon carcinoma cells generates systemic immunity in the inoculated hosts.2003

    • Author(s)
      Ugai, S., Shimozato, O., Kawamura, K., Wang, Y-Q., Yamaguchi, T., Saisho, H., Sakiyama, S, Tagawa, M.
    • Journal Title

      Cancer Gene Ther. 10

      Pages: 187-192

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590706
  • [Journal Article] Stage-specific expression of Clast6/E3/LAPTM5 during B cell differentiation : elevated expression in human B lymphomas.2003

    • Author(s)
      Seimiya, M., O-Wang, J., Bahar, R., Kawamura, K., Wang, Y., Saisho, H., Tagawa, M.
    • Journal Title

      Int.J.Oncol. 22

      Pages: 301-304

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590706
  • [Journal Article] Down-regulated expression of CCAAT/enhancer binding protein α and β genes in human hepatocellular carcinoma : a possible prognostic marker.2003

    • Author(s)
      Tomizawa, M., Watanabe, K., Saisho, H., Nakagawara, A., Tagawa, M.
    • Journal Title

      Anticancer Res. 23

      Pages: 351-354

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590706
  • [Journal Article] Preoperative serum midkine concentration is a prognostic marker for esophageal squamous cell carcinoma.2003

    • Author(s)
      Shimada H, Nabeya Y, Tagawa M, Okazumi S, Matsubara H, Ochiai T., et al.
    • Journal Title

      Cancer Sci 94

      Pages: 628-632

    • NAID

      10011688973

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370377
  • [Journal Article] Cytotoxicity of adenoviruses expressing the wild-type p53 gene to esophageal carcinoma cells is linked with the CAR expression level and indirectly with the endogenous

    • Author(s)
      Ma, G., Kawamura, K., Li, Q., Suzuki, N., Liang, M., Namba, M., Shimada, H. and Tagawa, M
    • Journal Title

      Cancer Gene Ther (in press)

      Pages: 53-53

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590798
  • [Presentation] A drug targeting the G2/M phases enhances replications and cytotoxicity of oncolytic adenoviruses in p53-deficient cells2022

    • Author(s)
      Takao Morinaga, Masatoshi Tagawa
    • Organizer
      14th International Oncolytic Virotherapy Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K08199
  • [Presentation] An MDM2 inhibitor induces expression of NFI, a cellular factor for adenovirus replications, and augmented cytotoxic effects of adenoviruses through DNA damage pathways2022

    • Author(s)
      Masatoshi Tagawa, Thao Thi Thanh Nguyen, Takao Morinaga, Yuji Tada, Kenzo Hiroshima
    • Organizer
      14th International Oncolytic Virotherapy Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K08199
  • [Presentation] Activation or suppression of immune responses for oncolytic virus therapy.2019

    • Author(s)
      Masatoshi Tagawa.
    • Organizer
      International Forum on Regulatory Sciences for Advanced Therapy Medical Products
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K10617
  • [Presentation] Increased p53 expression augments DNA damages and viral replications of p53-activating oncolytic adenoviruses through NF1 induction in mesothelioma with the wild-type p53 genotype.2019

    • Author(s)
      Masatoshi Tagawa, Yuji Tada, Hideaki Shimada, Kenzo Hiroshima.
    • Organizer
      12th Annual Conference of International Oncolytic Virus Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K10617
  • [Presentation] Cytotoxicity of Replication-Competent Adenoviruses Defective of E1B55kDa Molecules Is Irrelevant to P53 Expression, but Increases with a P53-Augmenting MDM2 Inhibitor through DNA Damages and Enhanced Viral Propagations in Mesothelioma with the Wild-Type P53 Genotype2018

    • Author(s)
      Thao Thi Thanh Nguyen, Takao Morinaga, Boya Zhong, Shuji Kubo, Masato Shingyoji, Yuji Tada, Yuichi Takiguchi, Koichiro Tatsumi, Hideaki Shimada, Kenzo Hiroshima, Masatoshi Tagawa
    • Organizer
      21st annual meeting of American Society of Gene and Cell Therapy
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09598
  • [Presentation] An MDM2 inhibitor achieves synergistic cytotoxicity with oncolytic adenoviruses on mesothelioma with the wild-type p53 gene.2018

    • Author(s)
      Masatoshi Tagawa, Thao Thi Thanh Nguyen, Takao Morinaga, Masato Shingyoji, Yuji Tada, Koichiro Tatsumi, Hideaki Shimada, Kenzo Hiroshima
    • Organizer
      The 14th international conference of the international mesothelioma interested group
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09598
  • [Presentation] HSP90阻害剤は内因性p53発現を上昇させるが外因性p53発現をプロテアソーム活性で抑制する2018

    • Author(s)
      田川雅敏、盛永敬郎、鐘博雅、Nguyen Thi Thanh Thao、久保秀司、多田裕司、巽浩一郎、島田英昭、廣島健三、山口直人
    • Organizer
      第77回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-17K10617
  • [Presentation] 核酸合成酵素非依存的なペメトレキセート耐性はAICARTを介したAMPKの活性化に関与している2018

    • Author(s)
      鐘博雅、関根郁夫、滝口裕一、グエン タオ、盛永敬郎、多田裕司、山口直人、田川雅敏
    • Organizer
      第77回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-17K10617
  • [Presentation] A Wee1 kinase inhibitor increases apoptosis of replication-competent adenoviruses through induction of mitotic catastrophe and enhancement of viral replications2017

    • Author(s)
      Takao Morinaga, Thao Thi Thanh Nguyen, Boya Zhong, Shuji Kubo, Masato Shingyoji, Yuji Tada, Koichiro Tatsumi, Hideaki Shimada, Kenzo Hiroshima, Masatoshi Tagawa
    • Organizer
      23rd annual meeting of Japan Society of Gene Therapy
    • Data Source
      KAKENHI-PROJECT-17K10617
  • [Presentation] An inhibitor for the MDM2-p53 Interaction Produces Synergistic Cytotoxicity with Oncolytic Adenoviruses on Mesothelioma with Wild-type p53 Genotype2017

    • Author(s)
      Masatoshi Tagawa, Thao Thi Thanh Nguyen, Takao Morinaga, Boya Zhong, Michiko Hanazono, Shuji Kubo, Masato Shingyoji, Yuji Tada, Koichiro Tatsumi, Hideaki Shimada, Kenzo Hiroshima
    • Organizer
      20th annual meeting of American Society of Gene and Cell Therapy
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09598
  • [Presentation] A MDM2 inhibitor augments cytotoxicity of oncolytic adenoviruses defective of E1B 55kDa molecules through enhancing DNA damages and apoptosis in mesothelioma2017

    • Author(s)
      Masatoshi Tagawa, Thao Thi Thanh Nguyen, Takao Morinaga, Boya Zhong, Michiko Hanazono, Shuji Kubo, Masato Shingyoji, Yuji Tada, Koichiro Tatsumi, Hideaki Shimada, Kenzo Hiroshima
    • Organizer
      23rd annual meeting of Japan Society of Gene Therapy
    • Data Source
      KAKENHI-PROJECT-16K09598
  • [Presentation] 悪性中皮腫におけるペメトレキセド耐性はAMPKの活性化が関与する2017

    • Author(s)
      鐘 博雅、関根 郁夫、滝口 裕一、グエン・タオ 、盛永 敬郎、多田 裕司、山口 直人、田川 雅敏
    • Organizer
      第76回日本癌学会総会
    • Data Source
      KAKENHI-PROJECT-26461183
  • [Presentation] A role of Wee1 kinase in adenoviruses-induced cell death and viral replication2017

    • Author(s)
      盛永敬郎、グエン タオ、鐘博雅、久保秀司、関根郁夫、多田裕司、巽浩一郎、島田英昭、廣島健三、田川雅敏
    • Organizer
      第76回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-17K10617
  • [Presentation] Enhanced expression of endogenous p53 contributes to E1B55-defective adenoviruses-induced cell death of mesothelioma deleted in the INK4a/ARF region2016

    • Author(s)
      Yuji Tada, Thi Thanh Thao Nguyen, Shuji Kubo, Masato Shingyoji, Ikuo Sekine, Koichiro Tatsumi, Hideaki Shimada, Kenzo Hiroshima, Masatoshi Tagawa
    • Organizer
      Tenth international meeting on replicating oncolytic virus therapeutics
    • Place of Presentation
      Vancouver, Canada
    • Year and Date
      2016-10-01
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461183
  • [Presentation] Combination of nutlin-3a and HSP90 inhibitors produces synergistic cytotoxicity on mesothelioma with the wild-type p53.2016

    • Author(s)
      Masatoshi Tagawa, Shinya Okamoto, Takao Morinaga, Masato Shingyoji, Ikuo Sekine, Toshio Suzuki, Yuji Tada, Koichiro Tatsumi, Hideaki Shimada, Kenzo Hiroshima
    • Organizer
      The 13th international conference of the international mesothelioma interested group
    • Place of Presentation
      Birmingham, UK
    • Year and Date
      2016-05-01
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461183
  • [Presentation] MDM2 and MDM4 inhibitors in combination with adenoviruses up-regulating p53 produce synergistic anti-tumor effects on mesothelioma through augmenting apoptotic processes2016

    • Author(s)
      Masatoshi Tagawa, Taka-aki Kozono, Yiyang Qin, Xue Rao Ning, Takao Morinaga, Shuji Kubo, Masato Shingyoji, Ikuo Sekine, Yuji Tada, Koichiro Tatsumi, Hideaki Shimada, Kenzo Hiroshima
    • Organizer
      22th annual meeting of Japan Society of Gene Therapy
    • Place of Presentation
      虎ノ門ヒルズフォーラム(東京)
    • Year and Date
      2016-07-28
    • Data Source
      KAKENHI-PROJECT-26462000
  • [Presentation] 細胞周期促進は増殖性アデノウイルスによるアポトーシスを増強する2016

    • Author(s)
      盛永敬郎, グエンタオ, チョンボウヤア, 久保秀司, 関根郁夫, 多田裕司, 巽浩一郎, 島田英昭, 廣島健三, 田川雅敏
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(横浜)
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-26462000
  • [Presentation] E1B-55kDa-defective adenoviruses produced cytotoxicity in combination with MDM2 inhibitors on INK4A/ARF-defective mesothelioma2016

    • Author(s)
      Yuji Tada, Thi Thanh Thao Nguyen, Shuji Kubo, Masato Shingyoji, Ikuo Sekine, Koichiro Tatsumi, Hideaki Shimada, Kenzo Hiroshima, Masatoshi Tagawa
    • Organizer
      2016 ESGCT and ISSCR Congress
    • Place of Presentation
      Florence, Italy
    • Year and Date
      2016-10-18
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461183
  • [Presentation] MDM2 and MDM4 inhibitors in combination with adenoviruses up-regulating p53 produce synergistic anti-tumor effects on mesothelioma through augmenting apoptotic processes2016

    • Author(s)
      Masatoshi Tagawa, Taka-aki Kozono, Yiyang Qin, Xue Rao Ning, Takao Morinaga, Shuji Kubo, Masato Shingyoji, Ikuo Sekine, Yuji Tada, Koichiro Tatsumi, Hideaki Shimada, Kenzo Hiroshima
    • Organizer
      22th annual meeting of Japan Society of Gene Therapy
    • Place of Presentation
      Tokyo, Japan
    • Year and Date
      2016-07-28
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461183
  • [Presentation] Combination of nutlin-3a and HSP90 inhibitors produces synergistic cytotoxicity on mesothelioma with the wild-type p532016

    • Author(s)
      Masatoshi Tagawa, Shinya Okamoto, Takao Morinaga, Masato Shingyoji, Ikuo Sekine, Toshio Suzuki, Yuji Tada, Koichiro Tatsumi, Hideaki Shimada, Kenzo Hiroshima
    • Organizer
      The 13th international conference of the international mesothelioma interested group
    • Place of Presentation
      Birmingham(UK)
    • Year and Date
      2016-05-01
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09598
  • [Presentation] MDMX阻害剤の悪性中皮腫に対する細胞傷害活性はp53非依存的であるが、MDM2阻害剤とは相乗的な併用効果を示すA MDMX inhibitor produces cytotoxicity in a p53-independent manner but achieves synergistic actions with MDM2 inhibitors2016

    • Author(s)
      田川雅敏、盛永敬郎、チョンボウヤア、グエンタオ、久保秀司、関根郁夫、多田裕司、巽浩一郎、島田英昭、廣島健三
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(横浜市神奈川県)
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-26461183
  • [Presentation] Enhanced expression of endogenous p53 contributes to E1B55-defective adenoviruses-induced cell death of mesothelioma deleted in the INK4a/ARF region2016

    • Author(s)
      Yuji Tada, Thi Thanh Thao Nguyen, Shuji Kubo, Masato Shingyoji, Ikuo Sekine, Koichiro Tatsumi, Hideaki Shimada, Kenzo Hiroshima, Masatoshi Tagawa
    • Organizer
      Tenth international meeting on replicating oncolytic virus therapeutics
    • Place of Presentation
      Vancouver(Canada)
    • Year and Date
      2016-10-01
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09598
  • [Presentation] Combination of Forced Transduction of P53 and an Agent That Blocks MDM2-p53 Interactions Produces Synergistic Cytotoxicity on Mesothelioma Defective of the INK4A/ARF Region2016

    • Author(s)
      Masatoshi Tagawa, Takao Morinaga, Zhihan Li, Thao Thi Thanh Nguyen, Boya Zhong, Shuji Kubo, Masato Shingyoji, Ikuo Sekine, Yuji Tada, Koichiro Tatsumi, Hideaki Shimada, Kenzo Hiroshima
    • Organizer
      19th annual meeting of American Society of Gene and Cell Therapy
    • Place of Presentation
      Washington DC, USA
    • Year and Date
      2016-05-04
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461183
  • [Presentation] 悪性中皮腫細胞に対してHSP90 阻害剤はAKT とMDMX 活性を阻害し、Nutlin-3a と相乗的な抗腫瘍効果を示す2015

    • Author(s)
      李知瀚、岡本慎也、盛永敬郎、江媛媛、久保秀司、関根郁夫、滝口裕一、多田裕司、巽浩一郎、島田英昭、廣島健三、田川雅敏
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場(名古屋)
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-26461183
  • [Presentation] Cytotoxicity by Adenovirus Replications is Associated with DNA Damages and the Activated P53 Pathways and is Dependent on Reactive Oxygen Species.2015

    • Author(s)
      Masatoshi Tagawa, Kiyoko Kawamura, Shinya Okamoto, Yuanyuan Jiang, Zhihan Li, Takao Morinaga, Shuji Kubo, Masato Shingyoji, Ikuo Sekine, Yuji Tada, Koichiro Tatsumi, Hideaki Shimada, Kenzo Hiroshima
    • Organizer
      18th annual meeting of American Society of Gene and Cell Therapy
    • Place of Presentation
      New Orleans, USA
    • Year and Date
      2015-05-13
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26462000
  • [Presentation] Heat shock protein 90 inhibitors augment endogenous p53 in p53 wild-type tumors but suppress Ad-mediated over-expressed exogenous p53 levels.2015

    • Author(s)
      Masatoshi Tagawa, Shinya Okamoto, Takao Morinaga, Taka-Aki Kozono, Shuji Kubo, Masato Shingyoji, Ikuo Sekine, Yuji Tada, Koichiro Tatsumi, Hideaki Shimada, Kenzo Hiroshima
    • Organizer
      21th annual meeting of Japan Society of Gene Therapy
    • Place of Presentation
      大阪市
    • Year and Date
      2015-07-24
    • Data Source
      KAKENHI-PROJECT-26462000
  • [Presentation] アデノウイルス製剤を用いた悪性中皮腫に対する遺伝子治療の実施にむけて2014

    • Author(s)
      田川雅敏, 多田裕司、新行内雅斗,由佐俊和,島田英昭,廣島健三,巽浩一郎
    • Organizer
      第21回石綿・中皮腫研究会
    • Place of Presentation
      名古屋市熱田区
    • Year and Date
      2014-10-11
    • Data Source
      KAKENHI-PROJECT-24591185
  • [Presentation] Anti-tumor effects of Ad-p53 on INK4A/ARF-defective mesothelioma are influenced positively by small G protein inhibitors but negatively by heat shock protein 90 inhibitors.2013

    • Author(s)
      Masatoshi Tagawa, Kuan Chai, Yuanyuan Jiang, Kiyoko Kawamura, Shan Yang, Atsushi Ogino, Naoto Yamaguchi, Kazunori Kato, Yuji Tada, Yuichi Takiguchi, Koichiro Tatsumi, Hideaki Shimada, Kenzo Hiroshima and Shuji Kubo
    • Organizer
      16th annual meeting of American Society of Gene and Cell Therapy
    • Place of Presentation
      Salt Lake City, USA
    • Data Source
      KAKENHI-PROJECT-24591185
  • [Presentation] Oncolytic effects of a fiber knob substituted adenovirus vector to human lung cancer cells2013

    • Author(s)
      Nagaya H, Kanno T, Hiwasa K, Nakagawa Y, Shimomura K, Nakano T, Nishizaki T, Tagawa M, Gotoh A
    • Organizer
      第19回日本遺伝子治療学会年次学術集会
    • Place of Presentation
      岡山
    • Data Source
      KAKENHI-PROJECT-23592354
  • [Presentation] Cytotoxicity of replication-competent adenoviruses are enhanced by co-transduced p53 gene.2013

    • Author(s)
      Masatoshi Tagawa, Shan Yang, Kiyoko Kawamura, Shinya Okamoto, Shuji Kubo, Yuji Tada, Kenzo Hiroshima, Hideaki Shimada
    • Organizer
      21th Annual Congress of the European Society of Gene and Cell Therapy
    • Place of Presentation
      Madrid, Spain
    • Data Source
      KAKENHI-PROJECT-24591185
  • [Presentation] A Cancer-targeting ligand strongly enhances oncolytic activity of a conditionally replicative adenovirus.2013

    • Author(s)
      Yuki Yamamoto, Naoko Goto, Shumpei Ohnami, Masatoshi Tagawa and Kazunori Aoki
    • Organizer
      16th annual meeting of American Society of Gene and Cell Therapy
    • Place of Presentation
      Salt Lake City, USA
    • Data Source
      KAKENHI-PROJECT-23591951
  • [Presentation] Updated gene therapy for malignant mesothelioma: Challenges for the intractable caner.2013

    • Author(s)
      Masatoshi Tagawa, Yuji Tada, Hideaki Shimada and Kenzo Hiroshima
    • Organizer
      19th annual meeting of Japan Society of Gene Therapy
    • Place of Presentation
      Okayama, Japan
    • Data Source
      KAKENHI-PROJECT-23591951
  • [Presentation] Midkine promoter-driven oncolytic adenovirus with Ad35 fiber modification achieves enhanced transduction of human osteosarcoma cells.2013

    • Author(s)
      Shuji Kubo, Misato Takagi-Kimura, Atsuko Tamamoto, Nobutaka Okamura, Masatoshi Tagawa, Noriyuki Kasahara, Haruki Okamura and Tomoko Hashimoto-Tamaoki
    • Organizer
      19th annual meeting of Japan Society of Gene Therapy
    • Place of Presentation
      Okayama, Japan
    • Data Source
      KAKENHI-PROJECT-23591951
  • [Presentation] Activation of p53 pathways produces combinatory effects with chemotherapeutic agents on p53 wild-type mesothelioma.2013

    • Author(s)
      Masatoshi Tagawa, Kiyoko Kawamura, Shan Yang, Yuanyuan Jiang, Kuan Chai, Naoto Yamaguchi, Yuji Tada, Yuichi Takiguchi, Koichiro Tatsumi, Hideaki Shimada and Kenzo Hiroshima
    • Organizer
      19th annual meeting of Japan Society of Gene Therap
    • Place of Presentation
      Okayama
    • Data Source
      KAKENHI-PROJECT-24591185
  • [Presentation] An HSP90 inhibitor, which blocks p53 degradation, suppresses adenoviruses-mediated p53 production and the apoptosis2013

    • Author(s)
      柴 寛、荻野 敦史、多田 裕司、関根 郁夫、滝口 裕一、巽 浩一郎、島田 英昭、廣島 健三、加藤 和則、山口 直人、田川 雅敏
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-23591951
  • [Presentation] Development of doubly regulated oncolytic adenovirus for human malignant mesothelioma.2013

    • Author(s)
      Shuji Kubo, Misato Takagi-Kimura, Atsuko Tamamoto, Tomoko Hashimoto-Tamaoki, Noriyuki Kasahara and Masatoshi Tagawa
    • Organizer
      16th annual meeting of American Society of Gene and Cell Therapy
    • Place of Presentation
      Salt Lake City, USA
    • Data Source
      KAKENHI-PROJECT-23591951
  • [Presentation] Updated gene therapy for malignant mesothelioma : Challenges for the intractable caner2013

    • Author(s)
      Masatoshi Tagawa, その他
    • Organizer
      19th annual meeting of Japan Society of Gene Therapy
    • Place of Presentation
      Okayama
    • Year and Date
      2013-07-06
    • Data Source
      KAKENHI-PROJECT-23591951
  • [Presentation] Oncolytic effects of a fiber knob substituted adenovirus vector to human lung cancer cells.2013

    • Author(s)
      Nagaya H, Kanno T, Hiwasa K, Nakagawa Y, Shimomura K, Nakano T, Nishizaki T, Tagawa M, Gotoh A
    • Organizer
      第19回日本遺伝子治療学会年次学術集会
    • Place of Presentation
      岡山
    • Data Source
      KAKENHI-PROJECT-23592354
  • [Presentation] Gene therapy for malignant mesothelioma with restored p53 functions2012

    • Author(s)
      Masatoshi Tagawa, その他
    • Organizer
      International Society for Cell and Gene Therapy of Cancer2012 Singapore Conference
    • Place of Presentation
      Singapore
    • Year and Date
      2012-10-05
    • Data Source
      KAKENHI-PROJECT-23591951
  • [Presentation] 腎癌細胞株に対するファイバー改変アデノウイルスベクターによるin vitroでの抗腫瘍効果の検討2012

    • Author(s)
      長屋寿雄、寺尾秀治、日和佐一弘、田川雅敏、後藤章暢
    • Organizer
      第21回 泌尿器科分子・細胞研究会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-23592354
  • [Presentation] Analysis of serum anti-galectin-1 antibody in stage I/II gastroenterological carcinomas.2012

    • Author(s)
      島田英昭、谷島 聡、小池淳一、田川雅敏、日和佐隆樹、松下一之、野村文夫
    • Organizer
      第71回日本癌学会学術総会
    • Place of Presentation
      札幌市
    • Data Source
      KAKENHI-PROJECT-23591951
  • [Presentation] Reactivation of p53-mediated pathways induces apoptosis in mesothelioma with wild-type p53 gene and produces combinatory synergistic effects with anti-cancer agents.2012

    • Author(s)
      Masatoshi Tagawa, Quanhai Li, Kiyoko Kawamura, Masato Shingyoji, Yuji Tada, Yuichi Takiguchi, Koichiro Tatsumi, Hideaki Shimada, Kenzo Hiroshima.
    • Organizer
      The11th international conference of the international mesothelioma interested group
    • Place of Presentation
      ボストン、米国
    • Data Source
      KAKENHI-PROJECT-24591185
  • [Presentation] Gene therapy for malignant mesothelioma with restored p53 functions.2012

    • Author(s)
      Masatoshi Tagawa, Kiyoko Kawamura, Shan Yang, Yuanyuan Jiang, Kuan Chai, Naoto Yamaguchi, Yuji Tada, Yuichi Takiguchi, Koichiro Tatsumi, Hideaki Shimada, Kenzo Hiroshima.
    • Organizer
      Internatinal Socieity for Cell and Gene Therapy of Cancer 2012
    • Place of Presentation
      シンガポール
    • Invited
    • Data Source
      KAKENHI-PROJECT-23591951
  • [Presentation] Oncolytic effects of a fiber knob substituted adenovirus vector to human bladder carcinoma cells.2012

    • Author(s)
      Nagaya H, Terao S, Hiwasa K, Tagawa M, Gotoh A.
    • Organizer
      第18回日本遺伝子治療学会年次学術集会
    • Place of Presentation
      ホテル熊本テルサ(熊本)
    • Data Source
      KAKENHI-PROJECT-23592354
  • [Presentation] Zoledronic acid, the third generation of bisphosphonates, produces anti-tumor effects on mesothelioma in vitro and in vivo through apoptosis or S phase arrest in p53-independent and Ras prenylation-independent manners.2012

    • Author(s)
      Yuji Tada, Quanhai Li, Kiyoko Kawamura, Hiroshi Kobayashi, Ikuo Sekine, Yuichi Takiguchi, Koichiro Tatsumi, Hideaki Shimada, Kenzo Hiroshima, Masatoshi Tagawa.
    • Organizer
      The11th international conference of the international mesothelioma interested group
    • Place of Presentation
      ボストン、米国
    • Data Source
      KAKENHI-PROJECT-24591185
  • [Presentation] Development of doubly regulated oncolytic adenovirus for human malignant mesothelioma.2012

    • Author(s)
      久保秀司、山野智基、吉川良恵、森永伴法、玉置知子、田川雅敏、笠原典之
    • Organizer
      第71回日本癌学会学術総会
    • Place of Presentation
      札幌市
    • Data Source
      KAKENHI-PROJECT-23591951
  • [Presentation] Cytotoxicity of replication-competent adenoviruses in esophageal carcinoma was enhanced by forced p53 expression.2012

    • Author(s)
      楊珊、川村希代子、江媛媛、柴 寛、久保秀司、山口直人、多田裕司、滝口裕一、巽浩一郎、島田英昭、廣島健三、田川雅敏
    • Organizer
      第71回日本癌学会学術総会
    • Place of Presentation
      札幌市
    • Data Source
      KAKENHI-PROJECT-23591951
  • [Presentation] A small G protein inhibitor, bisphosphonates, produces synergistic cytotoxicity on wild-type p53-bearing mesothelioma with adenoviruses up-regulating the p53 expression level.2012

    • Author(s)
      Masatoshi Tagawa, Kiyoko Kawamura, Shinya Okamoto, Jiang Yuan Yuan, Masato Shingyoji, Yuji Tada, Yuichi Takiguchi, Koichiro Tatsumi, Hideaki Shimada, Kenzo Hiroshima.
    • Organizer
      20th Annual Congress of the European Society of Gene and Cell Therapy
    • Place of Presentation
      ベルサイユ、フランス
    • Data Source
      KAKENHI-PROJECT-24591185
  • [Presentation] Bisphosphonates induce apoptosis through the suppression of Rab and produce combinatory effects with anti-cancer agents.2012

    • Author(s)
      田川雅敏、川村希代子、楊珊、江媛媛、柴 寛、久保秀司、山口直人、多田裕司、滝口裕一、巽浩一郎、島田英昭、廣島健三
    • Organizer
      第71回日本癌学会学術総会
    • Place of Presentation
      札幌市
    • Data Source
      KAKENHI-PROJECT-23591951
  • [Presentation] Bisphosphonates induce apoptosis through the suppression of Rab and produce combinatory effects with anti-cancer agents2012

    • Author(s)
      田川雅敏, その他
    • Organizer
      第71回日本癌学会学術総会
    • Place of Presentation
      札幌市
    • Year and Date
      2012-09-20
    • Data Source
      KAKENHI-PROJECT-23591951
  • [Presentation] Promoter-mediated replication of adenoviruses induces apoptosis-independent cell death in p53-null pancreatic carcinoma cells2011

    • Author(s)
      Masatoshi Tagawa, その他
    • Organizer
      14th annual meeting of American Society of Gene and Cell Therapy
    • Place of Presentation
      Seattle、USA
    • Year and Date
      2011-05-21
    • Data Source
      KAKENHI-PROJECT-23591951
  • [Presentation] Up-regulated p53 expression activates apoptotic pathways in wild-type p53-bearing mesothelioma and enhances cytotoxicity of the first-line chemotherapeutic agents2011

    • Author(s)
      Masatoshi Tagawa, その他
    • Organizer
      19th Annual Congress of the European Society of Gene and Cell Therapy
    • Place of Presentation
      Brighton, UK
    • Data Source
      KAKENHI-PROJECT-23591951
  • [Presentation] Up-regulated p53 expression activates apoptotic pathways in wild-type p53-bearing mesothelioma and enhances cytotoxicity of the first-line chemotherapeutic agents.2011

    • Author(s)
      Tagawa, M., その他
    • Organizer
      19th Annual Congress of the European Society of Gene and Cell Therapy
    • Place of Presentation
      ブライトン、英国
    • Data Source
      KAKENHI-PROJECT-23591951
  • [Presentation] Promoter-mediated replication of adenoviruses induces apoptosis-independent cell death in p53-null pancreatic carcinoma cells.2011

    • Author(s)
      Tagawa, M., その他
    • Organizer
      14th annual meeting of American Society of Gene and Cell Therapy
    • Place of Presentation
      シアトル、アメリカ
    • Data Source
      KAKENHI-PROJECT-23591951
  • [Presentation] 制限増殖型アデノウイルスは、膵がん細胞においてアポトーシス、オートファジー非依存的な細胞死を誘導する2011

    • Author(s)
      山内駿、川村希代子、岡本慎也、楊珊、江媛媛、深町利彦、小林弘、多田裕司、巽浩一郎、島田英昭、廣島健三、田川雅敏
    • Place of Presentation
      名古屋市
    • Year and Date
      2011-10-03
    • Data Source
      KAKENHI-PROJECT-21590879
  • [Presentation] Adenoviruses-mediated expression and cell-mediated delivery of interferon-lambda produced anti-tumor effects to human esophageal carcinoma in vivo.2010

    • Author(s)
      Masatoshi Tagawa, Quanhai Li, Kiyoko Kawamura, Shinya Okamoto, Shan Yang, Hiroshi Kobayashi, Muneo Numasaki, Yuji Tada, Kenzo Hiroshima, Hideaki Shimada.
    • Organizer
      ASGCT 2010 Clinical Trials Training Course and 13th Annual Meeting
    • Place of Presentation
      Mariott Wardman Park Hotel, Washington, DC, USA
    • Year and Date
      2010-05-22
    • Data Source
      KAKENHI-PROJECT-22590869
  • [Presentation] Adenoviruses-mediated expression and cell-mediated delivery of interferon-lambda produced anti-tumor effects to human esophageal carcinoma in vivo.2010

    • Author(s)
      Tagawa M., et al.
    • Organizer
      13th annual meeting of American Society of Gene and Cell Therapy
    • Place of Presentation
      Washington DC,USA
    • Year and Date
      2010-05-22
    • Data Source
      KAKENHI-PROJECT-20591585
  • [Presentation] インターフェロンラムダ発現型アデノウイルスによる食道がんに対する抗腫瘍効果2010

    • Author(s)
      田川雅敏、川村希代子、岡本慎也、楊珊、深町利彦、小林弘、藤江瞳、沼崎宗夫、島田英昭
    • Organizer
      第69回日本癌学会学術総会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-22590869
  • [Presentation] IL-17は血管内皮細胞のフラクタルカインの発現を増強することにより腫瘍の肺転移を抑制する2010

    • Author(s)
      藤江瞳, 田川雅敏, 沼崎宗夫
    • Organizer
      第69回日本癌学会学術総会
    • Place of Presentation
      大阪府大阪市・大阪国際会議場
    • Year and Date
      2010-09-22
    • Data Source
      KAKENHI-PROJECT-22590869
  • [Presentation] インターフェロンラムダ発現型アデノウイルスによる食道がんに対する抗腫瘍効果2010

    • Author(s)
      田川雅敏, 川村希代子, 岡本慎也, 楊珊, 深町利彦, 小林弘, 藤江瞳, 沼崎宗夫, 島田英昭
    • Organizer
      第69回日本癌学会学術総会
    • Place of Presentation
      大阪府大阪市・大阪国際会議場
    • Year and Date
      2010-09-23
    • Data Source
      KAKENHI-PROJECT-22590869
  • [Presentation] Adenoviruses-mediated expression and cell-mediated delivery of interferon-lambda produced anti-tumor effects to human esophageal carcinoma in vivo.2010

    • Author(s)
      田川雅敏, et al
    • Organizer
      13th annual meeting of American Society of Gene and Cell Therapy
    • Place of Presentation
      Washington DC
    • Year and Date
      2010-05-22
    • Data Source
      KAKENHI-PROJECT-20591585
  • [Presentation] Adenoviruses-mediated expression and cell-mediated delivery of interferon-lambda produced anti-tumor effects to human esophageal carcinoma in vivo2010

    • Author(s)
      Msatoshi Tagawa 、 Quanhai Li 、 Kiyoko Kawamura 、 Shinya Okamoto 、 Shan Yang 、Hiroshi Kobayashi 、Muneo Numasaki 、Yuji Tada、 Kenzo Hiroshima、 and Hideaki Shimada
    • Organizer
      ASGCT 2010 Clinical Trials Training Course and 13th Annual Meeting
    • Place of Presentation
      アメリカ
    • Data Source
      KAKENHI-PROJECT-22590869
  • [Presentation] 悪性中皮腫における細胞融解性アデノウイルス感受性の検討2010

    • Author(s)
      川村希代子、岡本慎也、深町利彦、小林弘、楊珊、久保秀司、山中満佳子、多田裕司、巽浩一郎、島田英昭、廣島健三、田川雅敏
    • Organizer
      第69回日本癌学会学術総会
    • Place of Presentation
      大阪市
    • Year and Date
      2010-09-23
    • Data Source
      KAKENHI-PROJECT-21590879
  • [Presentation] インターフェロンーラムダ発現型アデノウイルスによる食道がんに対する抗腫瘍効果2010

    • Author(s)
      田川雅敏、他
    • Organizer
      第69回日本癌学会学術総会
    • Place of Presentation
      大阪市
    • Year and Date
      2010-09-23
    • Data Source
      KAKENHI-PROJECT-20591585
  • [Presentation] Adenoviruses-mediated expression and cell-mediated delivery of interferon-lambda achieve anti-tumor effects in vivo.2010

    • Author(s)
      Msatoshi Tagawa, Quanhai Li, Kiyoko Kawamura, Shinya Okamoto, Shan Yang, Hitomi Fujie, Muneo Numasaki, Hideaki Shimada, Hiroshi Kobayashi
    • Organizer
      第16回日本遺伝子治療学会
    • Place of Presentation
      栃木県宇都宮市・栃木県総合文化センター
    • Year and Date
      2010-07-02
    • Data Source
      KAKENHI-PROJECT-22590869
  • [Presentation] Adenoviruses-mediated expression and cell-mediated delivery of interferon-lambda achieve anti-tumor effects in vivo2010

    • Author(s)
      Msatoshi Tagawa 、 Quanhai Li 、 Kiyoko Kawamura、 Shinya Okamoto、 Shan Yang、 Hitomi Fujie 、Muneo Numasaki 、Hideaki Shimada 、and Hiroshi Kobayashi
    • Organizer
      第16回日本遺伝子治療学会
    • Place of Presentation
      栃木
    • Data Source
      KAKENHI-PROJECT-22590869
  • [Presentation] IL-17 は血管内皮細胞のフラクタルカインの発現を増強することにより腫瘍の肺転移を抑制する2010

    • Author(s)
      藤江瞳、 田川雅敏、 沼崎宗夫
    • Organizer
      第69回日本癌学会学術総会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-22590869
  • [Presentation] Chimeric adenoviruses with the type 35 fiber-knob structure produce better cytotoxic effects to various human tumors with down-regulated coxsackievirus and adenovirus receptors2009

    • Author(s)
      Tagawa, M., et al.
    • Organizer
      12th annual meeting of American Society of Gene Therapy
    • Place of Presentation
      San Diego、USA
    • Year and Date
      2009-03-29
    • Data Source
      KAKENHI-PROJECT-20591585
  • [Presentation] Chimeric adenoviruses with the type 35 fiber-knob structure produce better cytotoxic effects to various human tumors with down-regulated coxsackievirus and adenovirus receptors.2009

    • Author(s)
      田川雅敏, et al
    • Organizer
      12th annual meeting of American Society of Gene Therapy
    • Place of Presentation
      San Diego
    • Year and Date
      2009-05-29
    • Data Source
      KAKENHI-PROJECT-20591585
  • [Presentation] 制限増殖型アデノウイルスに対する腫瘍細胞の感受性を決定する因子の検討2009

    • Author(s)
      川村希代子、李全海、武井優輝、山口直人、藤森浩中、多田裕司、山中満佳子、滝口裕一、巽浩一郎、廣島健三、島田英昭、田川雅敏
    • Organizer
      第68回日本癌学会学術総会
    • Place of Presentation
      横浜市
    • Year and Date
      2009-10-01
    • Data Source
      KAKENHI-PROJECT-21590879
  • [Presentation] ヒト膀胱癌細胞に対するミドカインプロモーターを組み込んだ増殖制限型アデノウイルスベクター(ADMKE1a)の有用性の検討2008

    • Author(s)
      寺尾秀治,白川利朗,Acharya, B.,鈴木透,乃美昌司,濱田雄行,田川雅敏,田中一志,武中篤,藤澤正人,後藤章暢
    • Organizer
      第46回日本癌治療学会総会
    • Place of Presentation
      名古屋
    • Year and Date
      2008-10-29
    • Data Source
      KAKENHI-PROJECT-20591871
  • [Presentation] Type 5 adenoviruses bearing the type 35-derived fiber-knob region enhanced the infectivity and increased the anti-tumor effects to CAR-low expressing tumors.2008

    • Author(s)
      田川雅敏, et al
    • Organizer
      16th Annual Congress of the European Society of Gene and Cell Therapy
    • Place of Presentation
      Brugge, Belgium
    • Year and Date
      2008-11-15
    • Data Source
      KAKENHI-PROJECT-20591585
  • [Presentation] Therapeutic efficacy of midkine promoter-based conditionally replicative adenovirus vector for targeting the midkine-expressing human bladder cancer cells.2008

    • Author(s)
      Terao S, Shirakawa, T., Acharya, B., Suzuki, T., Hamada, K., Tagawa, M., Tanaka, K., Takenaka, A., Fujisawa, M., Gotoh A
    • Organizer
      2008 International Society for Cell and Gene Therapy of Cancer China Conference
    • Place of Presentation
      Shijiazhuang, China
    • Year and Date
      2008-09-20
    • Data Source
      KAKENHI-PROJECT-20591871
  • [Presentation] アデノウイルスによる腫瘍細胞死に対して影響を与える細胞因子の検討2008

    • Author(s)
      川村希代子、馬 光宇、李 全海、植山太郎、廣島健三、島田英昭、多田裕司、滝口裕一、巽 浩一郎,栗山喬之、田川雅敏
    • Organizer
      第67回日本癌学会学術総会
    • Place of Presentation
      名古屋市
    • Year and Date
      2008-10-28
    • Data Source
      KAKENHI-PROJECT-19590798
  • [Presentation] Activation of p53 pathways with adenoviruses bearing the p53 gene and an inhibitor for the interaction between Mdm2 and p53 produces synergistic cytotoxicity in mesothelioma.

    • Author(s)
      Masatoshi Tagawa, Takaaki Kozono, Shinya Okamoto, Kengo Shimazu, Masato Shingyoji, Yuji Tada, Yuichi Takiguchi, Koichiro Tatsumi, Hideaki Shimada, Kenzo Hiroshima.
    • Organizer
      12th international conference of the international mesothelioma interested group
    • Place of Presentation
      Cape Town, South Africa
    • Year and Date
      2014-10-21 – 2014-10-24
    • Data Source
      KAKENHI-PROJECT-24591185
  • [Presentation] Transduced p53 enhances cytotoxic effects achieved withoncolytic adenoviruses on pancreatic carcinoma cells.

    • Author(s)
      江媛媛、岡本慎也、李知瀚、久保秀司、関根郁夫、滝口裕一、多田祐司、巽浩一郎、島田英昭、廣島健三、田川雅敏
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      横浜市
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PROJECT-26462000
  • [Presentation] A small molecule that inhibits p53 degradation influences cytotoxicity of Ad-p53 in INK4A/ARF-defective mesothelioma with wild-type p53 gene.

    • Author(s)
      Masatoshi Tagawa, Kiyoko Kawamura, Shinya Okamoto, Yuanyuan Jiang, Zhihan Li, Shuji Kubo, Masato Shingyoji, Yuji Tada, Yuichi Takiguchi, Koichiro Tatsumi, Hideaki Shimada, Kenzo Hiroshima
    • Organizer
      17th annual meeting of American Society of Gene and Cell Therapy
    • Place of Presentation
      Washington DC、USA
    • Year and Date
      2014-05-21 – 2014-05-24
    • Data Source
      KAKENHI-PROJECT-24591185
  • [Presentation] A new therapeutic strategy for cancer with replication-competent adenoviruses powered by the midkine promoter.

    • Author(s)
      Masatoshi Tagawa, Kiyoko Kawamura, Shinya Okamoto, Yuji Tada, Koichiro Tatsumi, Kenzo Hiroshima, Hideaki Shimada.
    • Organizer
      Third Midkine Symposium
    • Place of Presentation
      京都市
    • Year and Date
      2014-04-21 – 2014-04-23
    • Data Source
      KAKENHI-PROJECT-26462000
  • [Presentation] Immune response to tumor antigen, RalA, in patients with gastrointestinal cancers.

    • Author(s)
      島田英昭、谷島聡、小池淳一、松下一之、野村文夫、日和佐隆樹、田川雅敏
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      横浜市
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PROJECT-26462000
  • 1.  OH Keiyou (80231041)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 2.  SHIMADA Hideaki (20292691)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 36 results
  • 3.  KAWAMURA Kiyoko (80260248)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 25 results
  • 4.  OCHIAI Takenori (80114255)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 3 results
  • 5.  TAKENAGA Keizo (80260256)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 6.  後藤 澄雄 (10143273)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 7.  MATSUBARA Hisahiro (20282486)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 2 results
  • 8.  TANIGUCHI Masaru (80110310)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 9.  GUNJI Yoshio (60241957)
    # of Collaborated Projects: 4 results
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  • 10.  IWADATE Yasuo (70272309)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 11.  SAISHO Hiromitsu (10092058)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 4 results
  • 12.  YAMAGUCHI Taketo (00241969)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 1 results
  • 13.  YAMAURA Akira (40009717)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 14.  MASATO Shingyoji (60450433)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 21 results
  • 15.  GOTOH Akinobu (70283885)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 9 results
  • 16.  NAMBA Hiroki (60198405)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 17.  HIWASA Takaki (30260251)
    # of Collaborated Projects: 2 results
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    # of Collaborated Projects: 2 results
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    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
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    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 21.  NUMASAKI Muneo (50344677)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 14 results
  • 22.  HAGIWARA Kouiti (00240705)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  NAGAYA Hisao (60464343)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 24.  KADOTA Tomoko (00089864)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
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    # of Collaborated Projects: 1 results
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    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
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    # of Collaborated Projects: 1 results
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    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
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    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
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    # of Collaborated Products: 2 results
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    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
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    # of Collaborated Projects: 1 results
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    # of Collaborated Products: 7 results
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    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results
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    # of Collaborated Products: 1 results
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    # of Collaborated Products: 2 results
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    # of Collaborated Products: 1 results
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    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
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    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
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    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 60.  田辺 信宏
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    # of Collaborated Products: 1 results

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