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TACHIBANA Akira  立花 章

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立花 章

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Researcher Number 20188262
Other IDs
Affiliation (based on the past Project Information) *help 2012 – 2017: 茨城大学, 理学部, 教授
2006: 京都大字, 放射線・生物研究センター, 助教授
2000 – 2006: 京都大学, 放射線生物研究センター, 助教授
2004: 京都大学, 放射線・生物研究センター, 助教授
1993 – 2001: 京都大学, 放射線生物研究センター, 助手 … More
1994: 放射線生物研究センター, 助手
1991 – 1992: 京都大学, 医学部, 助手
1987 – 1988: 京都大学, 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
環境影響評価(含放射線生物学) / Risk sciences of radiation/Chemicals / Biological Sciences
Except Principal Investigator
Risk sciences of radiation/Chemicals / 環境影響評価(含放射線生物学) / Radiation science / Biological Sciences / Risk sciences of radiation and chemicals / 放射線5生物学
Keywords
Principal Investigator
放射線適応応答 / 欠失突然変異 / アタキシア・テランジェクタシア / DNA2本鎖切断修復 / p53 / radioadaptive response / DNA2本鎖切断 / 非相同的組換え / p53遺伝子 / deletion mutation … More / Hprt遺伝子 / 突然変異 / HPRT遺伝子 / 放射線誘発突然変異 / mutagenesis / end-joining / DNA double-strand break / low-dose radiation / multilex PCR / 突然変異生成 / エンドジョイニング / 低線量放射線 / ataxia-telangiectasia / radiation damage / RecQ hellcase / chromosome instability / DNA double-strand breaks / Bloom syndrome / DNA rejoining / 相同的組換え / 高発癌性劣性遺伝病 / 細胞内情報伝達系 / 染色体異常 / 放射線損傷 / RecQヘリカーゼ / 染色体不安定性 / ブルーム症候群 / DNA再結合反応 / non-homologous end-joining / MAP kinase / protein kinase C / p53 gene / cellular signal transduction / repair of double-strand breaks in DNA / MAPカイネース / プロテインカイネースC / 細胞内情報伝達 / mouse Hprt gene / mouse cells / DNA double strand break repair / radiation-induced mutation / マウス細胞 / 電離放射線誘発突然変異 / RNA干渉法 / DNA修復 / 非相同末端結合修復 / DNAリガーゼ / 非相同末端結合 / 2本鎖切断修復 / 遺伝的不安定性 / hprt 遺伝子 / 欠失切断点 / ゲノム不安定性 / ガンマ線 … More
Except Principal Investigator
色素性乾皮症 / DNA修復 / 突然変異 / non-homologous end-joining / homologous recombination / ブルーム症候群 / 突然変異スペクトル / 紫外線 / sub-lethal damage recovery / low dose-rate effects / DT40 / DSB / 緩照射 / 急照射 / NHEJ修復系 / HR修復系 / ニワトリ細胞 / low dose rate effects / sublethal damage repair / DNA double-strand break / knockout mutant / 非相同端末結合修復 / 低線量率照射 / 相同組換え修復 / DNA二重鎖切断 / ニワトリ細胞株 / tumor microenvironment / rediation-inducible genes / hypoxia / Gene therapy / 低酸素応答配列 / SAGE法 / 低酸素刺激誘導遺伝子 / 放射線誘導遺伝子 / 腫瘍特異的微小環境 / 放射線応答遺伝子 / 低酸素 / 遺伝子治療 / Bloom syndrome / Gene homing / Shaffron / Transposition / Transposon / Mobile genetic elements / DNA end-Joining / Illegitimate recombination / エンドヌクレアーゼ / DNAヘリカーゼ / DNA切断再結合 / RecQヘリカーゼ / DNAの切断と再結合 / シャフロン / トランスポゼース / 遺伝的組換え / DNAエンドジョイニング / DNA二本鎖切断 / トランスポゾン / 遺伝病 / 遺伝子ホーミング / 遺伝子スイッチ / 転移 / トラシスポゾン / 動く遺伝子 / エンドジョイニング / 非相同組換え / PCR法 / Trp-P_2誘発変異 / HPRTcDNA遺伝子 / サザーン・ブロット解析 / ウアバイン抵抗性 / 6チオグアニン抵抗性 / 近紫外光 / ヌードマウス / ファンコニ貧血 / Mer^- / DNA損傷 / がん原物質誘発変異 / シャトルベクター / HPRT遺伝子 / 6TG抵抗性変異 / 組織幹細胞 / in vivo / GFP / リスク評価 / 放射線 / 遺伝子 / 環境 / ゲノム解析 / 環境変異原 / 遺伝影響評価 / 生殖細胞突然変異 / 体細胞突然変異 / トランスジェニックメダカ / ノックインマウス / 放射線誘発突然変異 / 活性酸素 / がん抑制遺伝子 / がん遺伝子 / P53遺伝子 / ras遺伝子 / 皮膚がん / 修復 / 遺伝要因 / 相同組換え体 / 異型接合性喪失 / サザ-ン・ブロット / 1CR 191 / フレ-ムシフト / DAP抵抗性変異 / 末梢血管拡張性運動失調症 / γ(X)線 Less
  • Research Projects

    (22 results)
  • Research Products

    (62 results)
  • Co-Researchers

    (46 People)
  •  In vivo, in situ assessment of the mutagenic risk of radiation and environmental chemicals, using newly developed animal systems

    • Principal Investigator
      NODA Asao
    • Project Period (FY)
      2013 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Risk sciences of radiation and chemicals
    • Research Institution
      Radiation Effects Research Foundation
  •  Molecular analysis of the pathway of non-homologous end-joining involved in the radioadaptive responsePrincipal Investigator

    • Principal Investigator
      TACHIBANA Akira
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Risk sciences of radiation/Chemicals
    • Research Institution
      Ibaraki University
  •  Low dose-rate effects and non-homologous end-joining repair pathway of double strand breaks

    • Principal Investigator
      UTSUMI Hiroshi
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Risk sciences of radiation/Chemicals
    • Research Institution
      Health Research Foundation
  •  Molecular analysis of the role of p53 in radioadaptive responsePrincipal Investigator

    • Principal Investigator
      TACHIBANA Akira
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Risk sciences of radiation/Chemicals
    • Research Institution
      Kyoto University
  •  Role of DNA double-strand break repair on low dose rate effects

    • Principal Investigator
      UTSUMI Hiroshi
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      環境影響評価(含放射線生物学)
    • Research Institution
      KYOTO UNIVERSITY
  •  Novel developments on genetic recombination : DNA double-strand break and DNA end-joining

    • Principal Investigator
      OHTSUBO Eichi, 池田 日出男
    • Project Period (FY)
      1998 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
      Kitasato Institute
  •  Mechanism of rejoining of double-strand breaks in DNA in mammalian cellsPrincipal Investigator

    • Principal Investigator
      TACHIBANA Akira
    • Project Period (FY)
      1998 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kyoto University
  •  Nove| strategies for cancer treatment with tumor-specific gene therapy and radiotherapy

    • Principal Investigator
      HIRAOKA Masahiro
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Radiation science
    • Research Institution
      KYOTO UNIVERSITY
  •  DNA修復欠損細胞でのDNA2本鎖切断再結合の試験管内反応系による解析Principal Investigator

    • Principal Investigator
      立花 章
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto University
  •  Analysis of repair of double-strand breaks in DNA in the process of radioadaptive response using in vitro systemPrincipal Investigator

    • Principal Investigator
      TACHIBANA Akira
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      環境影響評価(含放射線生物学)
    • Research Institution
      KYOTO UNIVERSITY
  •  アタキシア・テランジェクタシア細胞の放射線誘発突然変異の分子的特性Principal Investigator

    • Principal Investigator
      立花 章
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto University
  •  Molecular analysis of induced mutation in radioadaptive response by low dose of radiation in mouse cellsPrincipal Investigator

    • Principal Investigator
      TACHIBANA Akira
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      環境影響評価(含放射線生物学)
    • Research Institution
      KYOTO UNIVERSITY
  •  アタキシア・テランジェクタシア細胞での電離放射線誘発ゲノム不安定性の検討Principal Investigator

    • Principal Investigator
      立花 章
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      環境影響評価(含放射線生物学)
    • Research Institution
      Kyoto University
  •  多段階発がんを促進する遺伝要因の作用機構

    • Principal Investigator
      武部 啓
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kyoto University
  •  アタキシア・テランジェクタシア患者由来リンパ芽球様細胞株におけるガンマ線誘発突然変異の分子的解析Principal Investigator

    • Principal Investigator
      立花 章
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      環境影響評価(含放射線生物学)
    • Research Institution
      Kyoto University
  •  多段階発がん過程を促進する遺伝的要因の作用機構

    • Principal Investigator
      武部 啓
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kyoto University
  •  多段階発がん過程を促進する遺伝的要因の作用機構

    • Principal Investigator
      武部 啓
    • Project Period (FY)
      1992 – 1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto University
  •  ヒト細胞における放射線誘発突然変異感受性の再評価

    • Principal Investigator
      巽 紘一
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      放射線5生物学
    • Research Institution
      Kyoto University
  •  がん原物質によるDNA損傷、修復と誘発突然変異特異性のシャトルベクターによる解析

    • Principal Investigator
      加藤 武司
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Osaka University
  •  がん原物質によるDNA損傷, 修復と誘発変異特異性のシャトルベクターによる解析

    • Principal Investigator
      加藤 武司
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Osaka University
  •  高発がん性遺伝病における発がん促進機構

    • Principal Investigator
      巽 紘一
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto University
  •  DNA修復遺伝子と発がん抑制

    • Principal Investigator
      武部 啓
    • Project Period (FY)
      1986 – 1987
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kyoto University

All 2017 2016 2015 2014 2013 2012 2006 2005 2004 2003 Other

All Journal Article Presentation

  • [Journal Article] Tissue-specific and time-dependent clonal expansion of ENU-induced mutant cells in gpt delta mice2017

    • Author(s)
      Nakayama Takafumi、Sawai Tomoko、Masuda Ikuko、Kaneko Shinya、Yamauchi Kazumi、Blyth Benjamin J.、Shimada Yoshiya、Tachibana Akira、Kakinuma Shizuko
    • Journal Title

      Environmental and Molecular Mutagenesis

      Volume: 58 Issue: 8 Pages: 592-606

    • DOI

      10.1002/em.22132

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25220102, KAKENHI-PROJECT-15H01834
  • [Journal Article] Rapid isolation of murine primary hepatocytes for chromosomal analysis.2017

    • Author(s)
      Ariyoshi K, Fujishima Y, Miura T, Shang Y, Kakinuma S, Yoshiya S, Kasai K, Nakata A, Tachibana A, Yoshida MA
    • Journal Title

      In Vitro Cell Dev Biol Anim

      Volume: in press Issue: 5 Pages: 474-478

    • DOI

      10.1007/s11626-017-0132-7

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26293270, KAKENHI-PROJECT-25220102
  • [Journal Article] Cancer risk at low doses of ionizing radiation: artificial neural networks inference from atomic bomb survivors.2014

    • Author(s)
      Sasaki, MS., Tachibana, A., Takeda, S.
    • Journal Title

      Journal of Radiation Research

      Volume: 55 Issue: 3 Pages: 391-406

    • DOI

      10.1093/jrr/rrt133

    • NAID

      120005439546

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24510064, KAKENHI-PROJECT-25220102
  • [Journal Article] Mutations in the FHA-domain of ectopically expressed NBS1 lead to Radiosensitization and to no increase in somatic mutation rates via a partial suppression of homologous recombination2014

    • Author(s)
      Maki Ohara, Yumi Funyu, Shunsuke Ebara, Yuki Sakamoto, Ryota Seki, Kenta Iijima, Akiko Ohishi, Junya Kobayashi, Kenshi Komatsu, Akira Tachibana, and Hiroshi Tauchi
    • Journal Title

      J. Radiat. Res

      Volume: 55 Issue: 4 Pages: 690-698

    • DOI

      10.1093/jrr/rru011

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23241021, KAKENHI-PROJECT-24310038, KAKENHI-PROJECT-24510064, KAKENHI-PUBLICLY-25112513, KAKENHI-PROJECT-25220102, KAKENHI-PROJECT-25550023, KAKENHI-PROJECT-25550026, KAKENHI-PROJECT-26241013, KAKENHI-PROJECT-26550025
  • [Journal Article] Mitochondria-Targeted Superoxide Dismutase (SOD2) Regulates Radiation Resistance and Radiation Stress Response in HeLa Cells2012

    • Author(s)
      Hosoki, A., S. Yonekura, Q-L. Zhao, Z-L. Wei, I. Takasaki, Y. Tabuchi, L-L. Wang, S. Hasuike, T. Nomura, A. Tachibana, K. Hashiguchi, S. Yonei, T. Kondo and Q-M. Zhang-Akiyama
    • Journal Title

      JRR

      Volume: 53 Issue: 1 Pages: 58-71

    • DOI

      10.1269/jrr.11034

    • NAID

      10030023538

    • ISSN
      0449-3060, 1349-9157
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21510056, KAKENHI-PROJECT-22390229, KAKENHI-PROJECT-23390386, KAKENHI-PROJECT-24510064, KAKENHI-PROJECT-24510071
  • [Journal Article] DNA repair defect in AT cells and their hypersensitivity to low-dose-rate radiation.2006

    • Author(s)
      Nakamura, H., Yasui, Y., Saito, N., Tachibana A., Komatsu, K., Ishizaki, K.
    • Journal Title

      Radiation Research 165(3)

      Pages: 277-282

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15510047
  • [Journal Article] DNA repair defect in AT cells and their hypersensitivity to low-dose-rate radiation.2006

    • Author(s)
      Nakamura, H., Yasui, Y., Saito, N., Tachibana, A., Komatsu, K., Ishizaki, K.
    • Journal Title

      Radiation Research 165 (3)

      Pages: 277-282

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15510047
  • [Journal Article] Increased sensitivity to sparsely ionizing radiation due to excessive base excision in clustered DNA damage sites in Escherichia coli.2005

    • Author(s)
      Chang, P.-W., Zhang, Q.-M., Takatori, K., Tachibana, A., Yonei, S.
    • Journal Title

      International Journal of Radiation Biology 81 (2)

      Pages: 115-123

    • NAID

      130005443149

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15510047
  • [Journal Article] Mutation Analyses of the Genes Responsible for Fanconi Anemia in Japanese Patients2005

    • Author(s)
      Tachibana, A
    • Journal Title

      Molecular Mechanisms of Fanconi Anemia. (eds. S.I.Ahmad & S.H.Kirk) 単巻

      Pages: 103-114

    • Data Source
      KAKENHI-PROJECT-15510047
  • [Journal Article] Increased sensitivity to sparsely ionizing radiation due to excessive base excision in clustered DNA damage sites in Escherichia coli.2005

    • Author(s)
      Chang, P.-W., Zhang, Q.-M., Takatori, K., Tachibana.A., Yonei, S.
    • Journal Title

      International Journal of Radiation Biology 81(2)

      Pages: 115-123

    • NAID

      130005443149

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15510047
  • [Journal Article] Cytotoxic and mutagenic effects of chronic low-dose-rate irradiation on TERT-immortalized human cells.2005

    • Author(s)
      Nakamura, H., Fukami, H., Hayashi, Y., Tachibana, A., Nakatsugawa, S., Hamaguchi, M., Ishizaki, K.
    • Journal Title

      Radiation Research 163 (3)

      Pages: 283-288

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15510047
  • [Journal Article] Cytotoxic and mutagenic effects of chronic low-dose-rate irradiation on TERT-immortalized human cells.2005

    • Author(s)
      Nakamura, H., Fukami, H., Hayashi, Y., Tachibana, A., Nakatsugawa, S., Hamaguchi, M., Ishizaki, K.
    • Journal Title

      Radiation Research 163(3)

      Pages: 283-288

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15510047
  • [Journal Article] Recombination repair pathway in the maintenance of chromosomal integrity against DNA interstrand crosslinks.2004

    • Author(s)
      Sasaki, M.S., Takata, M., Sonoda, E., Tachibana, A., Takeda, S.
    • Journal Title

      Cytogenetic and Genome Research 104

      Pages: 28-34

    • Data Source
      KAKENHI-PROJECT-15510047
  • [Journal Article] Low transposition frequency of the medaka fish Tol2 element may be due to extranuclear localization of its transposase.2004

    • Author(s)
      Iida, A., Tachibana, A., Hamada, S., Hori, H., Koga, A.
    • Journal Title

      Genes and Genetic Systems 79(2)

      Pages: 119-124

    • NAID

      10013129955

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15510047
  • [Journal Article] Genetic and physiological regulation of non-homologous end-joining in mammalian cells.2004

    • Author(s)
      Tachibana, A.
    • Journal Title

      Advances in Biophysics 38

      Pages: 21-44

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15510047
  • [Journal Article] Low transposition frequency of the medaka fish Tol2 element may be due to extranuclear localization of its transposase.2004

    • Author(s)
      Iida, A., Tachibana, A., Hamada, S., Hori, H., Koga, A.
    • Journal Title

      Genes and Genetic Systems 70(2)

      Pages: 119-124

    • NAID

      10013129955

    • Data Source
      KAKENHI-PROJECT-15510047
  • [Journal Article] No induction of p53 phosphorylation and few focus formation of phosphorylated H2AX suggest efficient repair of DNA damage during chronic low-dose-rate irradiation in human cells.2004

    • Author(s)
      Ishizaki, K., Hayashi, Y., Nakamura, H., Yasui, Y., Komatsu, K., Tachibana, A.
    • Journal Title

      Journal of Radiation Research 45 (4)

      Pages: 521-525

    • NAID

      110004041056

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15510047
  • [Journal Article] Genetic and physiological regulation of non-homologous end joining in mammalian cells.2004

    • Author(s)
      Tachibana, A.
    • Journal Title

      Advances in Biophysics 38

      Pages: 21-44

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15510047
  • [Journal Article] Genetic and physiological regulation of non-homologous end-joining in mammalian cells.2004

    • Author(s)
      Tachibana, A
    • Journal Title

      Advances in Biophysics 38

      Pages: 21-44

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16310040
  • [Journal Article] No induction of p53 phosphorylation and few focus formation of phosphorylated H2AX suggest efficient repair of DNA damage during chronic low-dose-rate irradiation in human cells.2004

    • Author(s)
      Ishizaki, K., Hayashi, Y., Nakamura, H., Yasui, Y., Komatsu, K., Tachibana, A.
    • Journal Title

      Journal of Radiation Research 45(4)

      Pages: 521-525

    • NAID

      110004041056

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15510047
  • [Journal Article] Genetic and physiological regulation of non-homologous end-joining in mammalian cells.2004

    • Author(s)
      Tachibana, A.
    • Journal Title

      Adv Biophys. 38

      Pages: 21-44

    • Data Source
      KAKENHI-PROJECT-16310040
  • [Journal Article] Stress induced premature senescence in hTERT-expressing ataxia telangiectasia fibroblasts.2004

    • Author(s)
      Naka, K., Tachibana, A., Ikeda, K., Motoyama, N.
    • Journal Title

      Journal of Biological Chemistry 279 (39)

      Pages: 2030-2037

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15510047
  • [Journal Article] Stress induced premature senescence in hTERT-expressing ataxia telangiectasia fibroblasts.2004

    • Author(s)
      Naka, K., Tachibana, A., Ikeda, K., Motoyama, N.
    • Journal Title

      Journal of Biological Chemistry 279(3)

      Pages: 2030-2037

    • Data Source
      KAKENHI-PROJECT-15510047
  • [Journal Article] Low transposition frequency of the medaka fish To12 element may be due to extranuclear localization of its transposase.2004

    • Author(s)
      Iida, A., Tachibana, A., Hamada, S., Hori, H., Koga, A
    • Journal Title

      Genes and Genetic Systems 79 (2)

      Pages: 119-124

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15510047
  • [Journal Article] Recombination repair pathway in the maintenance of chromosomal integrity against DNA interstrand crosslinks.2004

    • Author(s)
      Sasaki, M.S., Takata, M., Sonoda, E., Tachibana.A., Takeda, S.
    • Journal Title

      Cytogenetic and Genome Research 104(1-4)

      Pages: 28-34

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15510047
  • [Journal Article] Stress induced premature senescence in hTERT expressing ataxia telangiectasia fibroblasts.2004

    • Author(s)
      Naka, K., Tachibana, A., Ikeda, K., Motoyama, N.
    • Journal Title

      Journal of Biological Chemistry 279(3)

      Pages: 2030-2037

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15510047
  • [Journal Article] Recombination repair pathway in the maintenance of chromosomal integrity against DNA interstrand crosslinks.2004

    • Author(s)
      Sasaki, M.S., Takata, M., Sonoda, E., Tachibana, A., Takeda, S.
    • Journal Title

      Cytogenetic and Genome Research 104 (1-49)

      Pages: 28-34

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15510047
  • [Journal Article] The medaka fish Tol2 transposable element can undergo excision in human and mouse cells.2003

    • Author(s)
      Koga, A., Iida, A., Kamiya, M., Hayashi, R., Hori, H., Ishikawa, Y., Tachibana, A.
    • Journal Title

      Journal of Human Genetics 48 (5)

      Pages: 231-235

    • NAID

      10011594651

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15510047
  • [Journal Article] The medaka fish Tol2 transposable element can undergo excision in human and mouse cells.2003

    • Author(s)
      Koga, A., Iida, A., Kamiya, M., Hayashi, R., Hori, H., Ishikawa, Y., Tachibana, A.
    • Journal Title

      Journal of Human Genetics 48(5)

      Pages: 231-235

    • NAID

      10011594651

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15510047
  • [Presentation] 子ども期被ばくマウスの欠失突然変異に対するカロリー制限の影響2017

    • Author(s)
      杉菜々美、神代紗央理、佐川佳穂、中山貴文、尚 奕、鶴岡千鶴、谷 修祐、砂押正章、森岡孝満、B. J. Blyth、島田義也、柿沼志津子、立花 章
    • Organizer
      日本放射線影響学会
    • Data Source
      KAKENHI-PROJECT-25220102
  • [Presentation] 子ども期被ばくマウス脾臓における成体期開始カロリー制限の放射線誘発突然変異への影響2017

    • Author(s)
      神代紗央理、中山貴文、佐川佳穂、尚 奕、鶴岡千鶴、谷 修祐、砂押正章、森岡孝満、B. J. Blyth、島田義也、柿沼志津子、立花 章
    • Organizer
      日本放射線影響学会
    • Data Source
      KAKENHI-PROJECT-25220102
  • [Presentation] 成体期開始カロリー制限が子ども期被ばくマウスでの突然変異生成に及ぼす影響2017

    • Author(s)
      神代紗央理、中山貴文、佐川佳穂、尚 奕、鶴岡千鶴、谷 修祐、砂押正章、森岡孝満、B. J. Blyth、島田義也、柿沼志津子、立花 章
    • Organizer
      2017年度生命科学系学会合同年次大会(ConBio2017)
    • Data Source
      KAKENHI-PROJECT-25220102
  • [Presentation] 放射線適応応答誘導シグナルとしての酸化ストレスの関与の検討2017

    • Author(s)
      立花 章、長森夏海、高橋侑子、祢津安明、小林純也、中村麻子、秋山張 秋梅
    • Organizer
      2017年度生命科学系学会合同年次大会(ConBio2017)
    • Data Source
      KAKENHI-PROJECT-25220102
  • [Presentation] 放射線適応応答におけるp53リン酸化の解析2016

    • Author(s)
      祢津安明、安井尚彦、松永愛美、長森夏海、小林純也、立花章
    • Organizer
      日本放射線影響学会 第59回大会
    • Place of Presentation
      JMSアステールプラザ (広島市)
    • Data Source
      KAKENHI-PROJECT-25220102
  • [Presentation] 子ども被ばくによる誘発突然変異とカロリー制限の影響2016

    • Author(s)
      立花 章、神代紗央理、佐川佳穂、中山貴文、杉 菜々美、柿沼志津子、島田義也
    • Organizer
      日本放射線影響学会 第59回大会
    • Place of Presentation
      JMSアステールプラザ(広島市)
    • Data Source
      KAKENHI-PROJECT-25220102
  • [Presentation] 子ども被ばくマウス脾臓での遺伝子突然変異解析2015

    • Author(s)
      神代紗央理、佐川佳穂、中山貴文、尚 奕、鶴岡千鶴、谷 修佑、砂押正章、森岡孝満、Benjamin J Blyth、島田義也、柿沼志津子、立花 章
    • Organizer
      日本放射線影響学会ワークショップ
    • Place of Presentation
      富山大学(富山県富山市)
    • Year and Date
      2015-10-16
    • Data Source
      KAKENHI-PROJECT-25220102
  • [Presentation] γ線緩照射による放射線適応応答誘導へのp38 MAPKαの関与2014

    • Author(s)
      長森夏海、松永愛美、小林純也、立花 章
    • Organizer
      日本放射線影響学会第57回大会
    • Place of Presentation
      かごしま県民交流センター(鹿児島市)
    • Year and Date
      2014-10-01
    • Data Source
      KAKENHI-PROJECT-25220102
  • [Presentation] γ線緩照射による放射線適応応答誘導とその機構2014

    • Author(s)
      立花 章、長森夏海、松永愛美、郡司未佳、小林純也
    • Organizer
      日本放射線影響学会第57回大会
    • Place of Presentation
      かごしま県民交流センター(鹿児島市)
    • Year and Date
      2014-10-03
    • Data Source
      KAKENHI-PROJECT-25220102
  • [Presentation] gpt deltaマウスでのENU誘発突然変異の臓器特異性と発がんとの関連2013

    • Author(s)
      中山貴文、澤井知子、益田郁子、金子真也、島田義也、立花 章、柿沼志津子
    • Organizer
      日本放射線影響学会第56回大会
    • Place of Presentation
      青森市
    • Data Source
      KAKENHI-PROJECT-24510064
  • [Presentation] Age dependent role of Ikaros and Pten mutations in radiation T-cell lymphomagenesis in mice.2013

    • Author(s)
      Sunaoshi, M., Amasaki, Y., Hirano, S., Takabatake, T., Morioka, T., Nishimura, M., Shimada, Y., Tachibana, A., Kakinuma, S.
    • Organizer
      Kyoto T Cell Conference
    • Place of Presentation
      京都市
    • Data Source
      KAKENHI-PROJECT-24510064
  • [Presentation] 放射線誘発マウスTリンパ腫における遺伝子発現変動の被ばく時年齢依存性解析2013

    • Author(s)
      砂押正章、甘崎佳子、平野しのぶ、臺野和広、西村まゆみ、島田義也、立花 章、柿沼志津子
    • Organizer
      日本放射線影響学会第56回大会
    • Place of Presentation
      青森市
    • Data Source
      KAKENHI-PROJECT-24510064
  • [Presentation] The mechanism of the radioadaptive response induced by chronic γ-irradiation.2013

    • Author(s)
      Nagamori, N., Matsunaga, M., Kobayashi, J., Tachibana, A.
    • Organizer
      29th RBC-NIRS International Symposium
    • Place of Presentation
      京都市
    • Data Source
      KAKENHI-PROJECT-24510064
  • [Presentation] 放射線照射マウスにおけるAprt欠損突然変異の遺伝子解析2013

    • Author(s)
      立花 章、大賀千鈴、江刺達也、越 浩一、山内一巳、柿沼志津子、島田義也
    • Organizer
      日本放射線影響学会第56回大会
    • Place of Presentation
      青森市
    • Data Source
      KAKENHI-PROJECT-24510064
  • [Presentation] γ線緩照射による放射線適応応答誘導へのPKCαの関与2013

    • Author(s)
      長森夏海、松永愛美、小林純也、立花 章
    • Organizer
      日本放射線影響学会第56回大会
    • Place of Presentation
      青森市
    • Data Source
      KAKENHI-PROJECT-24510064
  • [Presentation] γ線緩照射による放射線適応応答の誘導機構2013

    • Author(s)
      長森夏海、松永愛美、小林純也、立花 章
    • Organizer
      日本原子力学会2013年秋の大会
    • Place of Presentation
      八戸市
    • Data Source
      KAKENHI-PROJECT-24510064
  • [Presentation] Age dependency of Ikaros and Pten alterations in radiation-induced T-cell lymphoma.2012

    • Author(s)
      Sunaoshi, M., Amasaki, Y., Hirano, S., Takabatake, T., Morioka, T., Nishimura, M., Shimada, Y., Tachibana, A., Kakinuma, S.
    • Organizer
      Childhood Cancer-2012; International Scientific Conference on Early Exposure and Childhood Cancer
    • Place of Presentation
      Church House Conference Centre, London
    • Data Source
      KAKENHI-PROJECT-24510064
  • [Presentation] 高感度検出系を用いた放射線感受性修飾効果の解析2012

    • Author(s)
      田内 広、江原俊介、船生悠美、大原麻希、宮本智弘、関 良太、小松賢志、立花 章
    • Organizer
      日本放射線影響学会第55回大会
    • Place of Presentation
      東北大学、仙台市
    • Data Source
      KAKENHI-PROJECT-24510064
  • [Presentation] トリチウムチミジンによる放射線適応応答誘導2012

    • Author(s)
      村田弘貴、立花 章
    • Organizer
      日本放射線影響学会第55回大会
    • Place of Presentation
      東北大学、仙台市
    • Data Source
      KAKENHI-PROJECT-24510064
  • [Presentation] DNA二重鎖切断修復におけるNBS1とATMの役割2012

    • Author(s)
      坂本裕貴、深作直子、阿部紘子、田中 彩、戸松静香、大原麻希、高田 穣、小松賢志、立花 章、田内 広
    • Organizer
      日本放射線影響学会第55回大会
    • Place of Presentation
      東北大学、仙台市
    • Data Source
      KAKENHI-PROJECT-24510064
  • [Presentation] ガンマ線緩照射による放射線適応応答の誘導2012

    • Author(s)
      立花 章、松永愛美、五月女淑歩、小林純也
    • Organizer
      日本放射線影響学会第55回大会
    • Place of Presentation
      東北大学、仙台市
    • Data Source
      KAKENHI-PROJECT-24510064
  • [Presentation] 放射線誘発HPRT欠損突然変異体に生じる遺伝子変化の解析2012

    • Author(s)
      牧 邦彦、山上有子、立花 章
    • Organizer
      日本放射線影響学会第55回大会
    • Place of Presentation
      東北大学、仙台市
    • Data Source
      KAKENHI-PROJECT-24510064
  • [Presentation] 放射線照射マウスにおけるAprt欠損突然変異の解析2012

    • Author(s)
      大賀千鈴、江刺達也、越 浩一、山内一巳、柿沼志津子、島田義也、立花 章
    • Organizer
      日本放射線影響学会第55回大会
    • Place of Presentation
      東北大学、仙台市
    • Data Source
      KAKENHI-PROJECT-24510064
  • [Presentation] p53遺伝子発現抑制細胞での放射線適応応答の検討2012

    • Author(s)
      安井尚彦、立花 章
    • Organizer
      日本放射線影響学会第55回大会
    • Place of Presentation
      東北大学、仙台市
    • Data Source
      KAKENHI-PROJECT-24510064
  • [Presentation] p38 MAPKノックダウン細胞におけるPKCaの活性2012

    • Author(s)
      村瀬 純、五月女淑歩、藤原竜真、立花 章
    • Organizer
      日本放射線影響学会第55回大会
    • Place of Presentation
      東北大学、仙台市
    • Data Source
      KAKENHI-PROJECT-24510064
  • [Presentation] 放射線適応応答におけるDNA ligase IIIとIVの関与

    • Author(s)
      湯田愛弥、吉井沙耶香、立花 章
    • Organizer
      日本放射線影響学会第57回大会
    • Place of Presentation
      かごしま県民交流センター、鹿児島市
    • Year and Date
      2014-10-01 – 2014-10-03
    • Data Source
      KAKENHI-PROJECT-24510064
  • [Presentation] γ線緩照射による放射線適応応答の誘導

    • Author(s)
      長森夏海、松永愛美、小林純也、立花 章
    • Organizer
      日本原子力学会北関東支部大会若手研究者発表会
    • Place of Presentation
      茨城県那珂郡東海村
    • Data Source
      KAKENHI-PROJECT-24510064
  • [Presentation] p53遺伝子欠損マウス細胞での突然変異解析実験条件の検討

    • Author(s)
      高須賀貴優、立花 章
    • Organizer
      日本放射線影響学会第57回大会
    • Place of Presentation
      かごしま県民交流センター(鹿児島市)
    • Year and Date
      2014-10-01 – 2014-10-03
    • Data Source
      KAKENHI-PROJECT-25220102
  • [Presentation] γ線緩照射による放射線適応応答誘導とその機構

    • Author(s)
      立花 章、長森夏海、松永愛美、郡司未佳、小林純也
    • Organizer
      日本放射線影響学会第57回大会
    • Place of Presentation
      かごしま県民交流センター、鹿児島市
    • Year and Date
      2014-10-01 – 2014-10-03
    • Invited
    • Data Source
      KAKENHI-PROJECT-24510064
  • [Presentation] 放射線誘発APRT欠損突然変異の塩基配列解析の試み

    • Author(s)
      立花 章、大賀千鈴、三浦佑子、早田真理子、野澤千裕、佐藤佳菜子、江刺達也、越 浩一、山内一巳、柿沼志津子、島田義也
    • Organizer
      日本放射線影響学会第57回大会
    • Place of Presentation
      かごしま県民交流センター(鹿児島市)
    • Year and Date
      2014-10-01 – 2014-10-03
    • Data Source
      KAKENHI-PROJECT-25220102
  • [Presentation] 放射線適応応答におけるDNA ligase IIIとIVの関与

    • Author(s)
      湯田愛弥、吉井沙耶香、立花 章
    • Organizer
      日本放射線影響学会第57回大会
    • Place of Presentation
      かごしま県民交流センター(鹿児島市)
    • Year and Date
      2014-10-01 – 2014-10-03
    • Data Source
      KAKENHI-PROJECT-25220102
  • [Presentation] γ線緩照射による放射線適応応答誘導へのp38 MAPKαの関与

    • Author(s)
      長森夏海、松永愛美、小林純也、立花 章
    • Organizer
      日本放射線影響学会第57回大会
    • Place of Presentation
      かごしま県民交流センター、鹿児島市
    • Year and Date
      2014-10-01 – 2014-10-03
    • Data Source
      KAKENHI-PROJECT-24510064
  • [Presentation] カロリー制限による放射線誘発胸腺リンパ腫と肺がんの抑制メカニズムの解明

    • Author(s)
      中山貴文、尚 奕、砂押正章、甘崎佳子、臺野和広、小川佳那依、島田義也、立花 章、柿沼志津子
    • Organizer
      日本放射線影響学会第57回大会
    • Place of Presentation
      かごしま県民交流センター(鹿児島市)
    • Year and Date
      2014-10-01 – 2014-10-03
    • Data Source
      KAKENHI-PROJECT-25220102
  • 1.  SASAKI Masao (20013857)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 2.  EJIMA Yosuke (50127057)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 3.  武部 啓 (10028318)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 4.  TODO Takeshi (90163948)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 5.  巽 紘一 (30131022)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 6.  錦織 千佳子 (50198454)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 7.  野村 大成 (90089871)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 8.  吉田 廸弘 (60001765)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 9.  山泉 克 (70107093)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 10.  OHTSUBO Eichi (10158800)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 11.  UTSUMI Hiroshi (20025646)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 12.  加藤 武司 (90028382)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 13.  木村 博 (00110560)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 14.  佐藤 弘毅 (60029775)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 15.  八木 孝司 (80182301)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 16.  池田 日出男 (10012775)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 17.  NODA Asao (40294227)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  YASUDA Takako (40450431)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  KOGA Akiniko (80192574)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  IIDA Shigeru (30012777)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  OGAWA Hideyuki (70028207)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  SKIGUCHI Mutsuo (00037342)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  HIRAOKA Masahiro (70173218)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  SASAI Keisuke (20225858)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  NODA Makoto (30146708)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  OYA Natuo (70281095)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  YASUHIRA Shinji (90311729)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  TANO Keizou (00183468)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  TAKAHASHI Akihisa (60275336)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  三谷 啓志 (70181922)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  濱崎 幹也 (80443597)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  山本 卓 (90244102)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 33.  石井 裕 (20028509)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 34.  巽 純子 (80128222)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 35.  栗原 孝行 (20064595)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 36.  尾川 博昭 (50108685)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 37.  古山 順一 (30068431)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 38.  近藤 直実 (50124714)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 39.  松浦 伸也 (90274133)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 40.  小松 賢志 (80124577)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 41.  志村 令郎 (60025426)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 42.  KASAI Kosuke
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 43.  小林 純也
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 44.  三浦 富智
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 45.  吉田 光明
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 46.  中田 章史
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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