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Takaori Akifumi  高折 晃史

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TAKAORI AKIFUMI  高折 晃史

高折 晃史  タカオリ アキフミ

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Researcher Number 20324626
Other IDs
Affiliation (Current) 2025: 京都大学, 医学研究科, 教授
Affiliation (based on the past Project Information) *help 2018 – 2023: 京都大学, 医学研究科, 教授
2017: 京都大学, 医学部附属病院, 教授
2016: 京都大学, 医学系研究科, 教授
2012 – 2016: 京都大学, 医学(系)研究科(研究院), 教授
2010 – 2016: 京都大学, 医学研究科, 教授 … More
2008 – 2009: Kyoto University, 医学研究科, 講師
2007: Kyoto University, Graduate School of Medicine, Assistant Professor
2006: 京都大学, 医学研究科, 助手
2001 – 2002: 京都大学, 医学研究科, 助手 Less
Review Section/Research Field
Principal Investigator
Virology / Biological Sciences / Basic Section 50010:Tumor biology-related
Except Principal Investigator
Infectious disease medicine / Biological Sciences / Basic Section 52010:General internal medicine-related / Basic Section 54010:Hematology and medical oncology-related / Medium-sized Section 43:Biology at molecular to cellular levels, and related fields / Structural biochemistry / Neo-Gerontology / Hematology / Biological Sciences / General internal medicine (including Psychosomatic medicine)
Keywords
Principal Investigator
感染症 / ウイルス / 宿主因子 / 蛋白質 / 核酸 / 免疫学 / マウスモデル / 癌の不均一性 / シングルセル解析 / CAGE法 … More / APOBEC signature / 治療抵抗性 / 癌の多様性 / 癌のクローン進化 / APOBEC3 / C-to-T変異 / シチジン脱アミノ化 / ゲノム変異 / クローン進化 / がん / APOBEC / Protein / Nucleic acid / Immunoloey / Infectious disease / Virus / 感染防御 / 免疫 / ゲノム / 変異 / 内在性免疫 / 進化 / 遺伝子 / 個体 / 遺伝子治療 / 感染性 / Vif / HIV-1 … More
Except Principal Investigator
エイズ / ウイルス / 次世代シークエンサー / 宿主因子 / HIV-1 / リポペプチド / APOBEC / 免疫学 / 感染症 / 自然免疫 / 老化 / red blood cell / immunity / extracellular vesicle / mesenchymal stem cell / 赤血球抗体 / 貧血 / COVID-19 / NK細胞多型 / 移植片対腫瘍効果 / 移植片対宿主病 / 免疫チェックポイント阻害剤 / KIRシグナル / 慢性骨髄性白血病 / 成人T細胞白血病 / NK細胞活性 / 全ゲノムシークエンシング / KIRアレル / 抗腫瘍免疫 / GVHD / KIR / NK細胞受容体 / 同種造血幹細胞移植 / ゲノム解析 / 腫瘍 / NET-CAGE法 / 造血器腫瘍 / 遺伝子発現制御 / ゲノム科学 / バイオインフォマティクス / 次世代シークエンシング / ノンコーディングゲノム・RNA / ヒトゲノム科学 / 造血器悪性腫瘍 / NET-CAGE / 転写ネットワーク / バイオマーカー / ゲノム解析技術 / エンハンサー / 白血病 / NMR / アプタマー / Vif / ポストゲノム / プロテオミクス / 数理科学 / 感染防御 / 共同研究インターンシップ / 許容性 / 宿主特異性 / 病原性発現 / 感染コンピテンシー / オミックス解析 / 数理科学解析 / 構造解析 / コンピテンシー / 内科 / 代謝 / クローン性造血 / 細胞障害性T細胞 / 体細胞変異 / 再生不良性貧血 / 血液免疫学 / 血液内科学 / Chemokine Receptor / Chemokine / AIDS Control / Immune response / Pathophysiology / Host Factors / 薬剤耐性 / 抗HIV剤 / 抗HIV免疫 / コレセプター / HIV複製 / ケモカイン受容体 / ケモカイン / 制御 / 免疫 / 病態 / 脂質 / 細胞・組織 / キラーT細胞 / 遺伝子 / ゲノム / 複製複合体 / イメージング / ストレス顆粒 / RIG-I / インターフェロン / 発癌 / ストレス老化 / 癌化 / 解糖系代謝 / 老年医学 Less
  • Research Projects

    (19 results)
  • Research Products

    (83 results)
  • Co-Researchers

    (51 People)
  •  COVID-19における赤血球結合抗体産生病態解明と細胞外小胞を応用した病態制御

    • Principal Investigator
      三浦 康生
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52010:General internal medicine-related
    • Research Institution
      Fujita Health University
  •  APOBEC3B-induced genome mutations and its contribution to clonal evolution in cancersPrincipal Investigator

    • Principal Investigator
      Takaori-Kondo Akifumi
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 50010:Tumor biology-related
    • Research Institution
      Kyoto University
  •  Optimizing immunomodulation of hematopoietic stem cell transplantation focusing on allelic polymorphisms of KIRs

    • Principal Investigator
      Shindo Takero
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54010:Hematology and medical oncology-related
    • Research Institution
      Kyoto University
  •  Comprehensive enhancer analysis and molecular pathogenesis of leukemia using our novel technology

    • Principal Investigator
      Murakawa Yasuhiro
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
    • Research Institution
      Institute of Physical and Chemical Research
  •  Investigation of the origin of clonal hematopoiesis in aplastic anemia

    • Principal Investigator
      OGAWA SEISHI
    • Project Period (FY)
      2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Hematology
    • Research Institution
      Kyoto University
  •  Study of lipopeptide-specific immunity against AIDS: from monkeys to humans

    • Principal Investigator
      SUGITA, Masahiko
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Infectious disease medicine
    • Research Institution
      Kyoto University
  •  Investigation for metabolic features in divergency of ageing

    • Principal Investigator
      Kondoh Hirohsi
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neo-Gerontology
    • Research Institution
      Kyoto University
  •  Elucidation of the mechanism by which virus inhibits the function of human anti-virus enzymes and molecular basis of drug discovery

    • Principal Investigator
      Nagata Takashi
    • Project Period (FY)
      2014 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Structural biochemistry
    • Research Institution
      Kyoto University
  •  Competition between viruses and intracellular antiviral immunity

    • Principal Investigator
      Fujita Takashi
    • Project Period (FY)
      2012 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Kyoto University
  •  Identification of cytotoxic T lymphocyte responses to lipopeptides in human immunodeficiency virus-infected patients.

    • Principal Investigator
      SUGITA Masahiko
    • Project Period (FY)
      2012
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Infectious disease medicine
    • Research Institution
      Kyoto University
  •  Molecular basis of host cell competency in virus infection

    • Principal Investigator
      NAGATA Kyosuke
    • Project Period (FY)
      2012 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      University of Tsukuba
  •  Study on in vivo function of APOBEC3 and its effect on pathophysiology of HIV-1 infectionPrincipal Investigator

    • Principal Investigator
      TAKAORI AKIFUMI
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Virology
    • Research Institution
      Kyoto University
  •  Senescence-inducing stress modulates glycolysis and the Warburg effect

    • Principal Investigator
      KONDOH Hiroshi
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General internal medicine (including Psychosomatic medicine)
    • Research Institution
      Kyoto University
  •  レトロウイルスによる抗ウイルス宿主因子アポベック蛋白回避機構に関する研究Principal Investigator

    • Principal Investigator
      高折 晃史
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kyoto University
  •  遺伝子操作の可能なin vivo HIV-1感染モデルマウスの作製Principal Investigator

    • Principal Investigator
      高折 晃史
    • Project Period (FY)
      2009
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Virology
    • Research Institution
      Kyoto University
  •  レトロウイルスによる抗ウイルス宿主因子アポベック蛋白回避機構に関する研究Principal Investigator

    • Principal Investigator
      高折 晃史
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kyoto University
  •  Studies on antiviral innate immunity by the APOBEC family proteinsPrincipal Investigator

    • Principal Investigator
      TAKAORI Akifumi
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Virology
    • Research Institution
      Kyoto University
  •  Basic Research for AIDS control

    • Principal Investigator
      UCHIYAMA Takashi
    • Project Period (FY)
      2002
    • Research Category
      特定領域研究
    • Review Section
      Biological Sciences
    • Research Institution
      Kyoto University
  •  HIV-1VifによるHIV-1の感染性制御機構に関する研究Principal Investigator

    • Principal Investigator
      高折 晃史
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Kyoto University

All 2022 2021 2020 2019 2017 2016 2015 2014 2013 2012 2008 2007 2006 Other

All Journal Article Presentation Book Other

  • [Book] 蛋白質核酸酵素増刊-ユビキチン-プロテアソーム系とオートファジー-2006

    • Author(s)
      高折 晃史
    • Total Pages
      1556
    • Publisher
      共立出版
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590449
  • [Journal Article] Dual inhibition of the MEK/ERK and PI3K/AKT pathways prevents pulmonary GVHD suppressing perivenulitis and bronchiolitis2022

    • Author(s)
      Muranushi Hiroyuki、Shindo Takero、Chen-Yoshikawa Toyofumi F、Yoshizawa Akihiko、Ngo Huong Thi、Gochi Fumiaki、Date Hiroshi、Takaori-Kondo Akifumi
    • Journal Title

      Blood Advances

      Volume: - Issue: 1 Pages: 106-121

    • DOI

      10.1182/bloodadvances.2021006678

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08812
  • [Journal Article] ILF2 enhances the DNA cytosine deaminase activity of tumor mutator APOBEC3B in multiple myeloma cells2022

    • Author(s)
      Kazuma Yasuhiro、Shirakawa Kotaro、Tashiro Yusuke、Yamazaki Hiroyuki、Nomura Ryosuke、Horisawa Yoshihito、Takeuchi Suguru、Stanford Emani、Konishi Yoshinobu、Matsui Hiroyuki、Matsumoto Tadahiko、Tanabe Fumiko、Morishita Ryo、Ito Shinji、Takaori-Kondo Akifumi
    • Journal Title

      Scientific Reports

      Volume: 12 Issue: 1 Pages: 2278-2278

    • DOI

      10.1038/s41598-022-06226-3

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03502, KAKENHI-PROJECT-20J01623
  • [Journal Article] Development of a novel Indium-111 radiolabeled mogamulizumab targeting CCR4 for imaging adult T-cell leukemia/lymphoma in vivo2022

    • Author(s)
      Shimizu Yoichi、Koyasu Sho、Suzukida Mari、Izumi Kiyotaka、Kidera Eitaro、Shindo Takero、Saga Tsuneo、Ono Masahiro、Takaori-Kondo Akifumi、Nakamoto Yuji
    • Journal Title

      Annals of Nuclear Medicine

      Volume: 36 Issue: 3 Pages: 319-326

    • DOI

      10.1007/s12149-021-01706-4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K08812, KAKENHI-PROJECT-19K17164
  • [Journal Article] Pharmacological MEK inhibition promotes polyclonal T-cell reconstitution and suppresses xenogeneic GVHD2021

    • Author(s)
      Itamura Hidekazu、Shindo Takero、Muranushi Hiroyuki、Kitaura Kazutaka、Okada Seiji、Shin-I Tadasu、Suzuki Ryuji、Takaori-Kondo Akifumi、Kimura Shinya
    • Journal Title

      Cellular Immunology

      Volume: 367 Pages: 104410-104410

    • DOI

      10.1016/j.cellimm.2021.104410

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K08812
  • [Journal Article] Next‐generation sequencing in two cases of de novo acute basophilic leukaemia2021

    • Author(s)
      Shimizu Takuya、Kondo Tadakazu、Nannya Yasuhito、Watanabe Mizuki、Kitawaki Toshio、Shindo Takero、Hishizawa Masakatsu、Yamashita Kouhei、Ogawa Seishi、Takaori‐Kondo Akifumi
    • Journal Title

      Journal of Cellular and Molecular Medicine

      Volume: 25 Issue: 14 Pages: 7095-7099

    • DOI

      10.1111/jcmm.16591

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K08812, KAKENHI-PROJECT-19H05656
  • [Journal Article] APOBEC3B is preferentially expressed at the G2/M phase of cell cycle2021

    • Author(s)
      Hirabayashi Shigeki、Shirakawa Kotaro、Horisawa Yoshihito、Matsumoto Tadahiko、Matsui Hiroyuki、Yamazaki Hiroyuki、Sarca Anamaria Daniela、Kazuma Yasuhiro、Nomura Ryosuke、Konishi Yoshinobu、Takeuchi Suguru、Stanford Emani、Kawaji Hideya、Murakawa Yasuhiro、Takaori-Kondo Akifumi
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 546 Pages: 178-184

    • DOI

      10.1016/j.bbrc.2021.02.008

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H03992, KAKENHI-PROJECT-19H03502, KAKENHI-PROJECT-20J01623, KAKENHI-PROJECT-19K07591, KAKENHI-PROJECT-20K21407, KAKENHI-PROJECT-20KK0186
  • [Journal Article] KIR3DL1 Allotype-Dependent Modulation of NK Cell Immunity against Chronic Myeloid Leukemia2021

    • Author(s)
      Izumi Kiyotaka、Shindo Takero、Ngo Huong Thi、Nakayama-Hosoya Kaori、Akahane Koshi、Tamai Minori、Nguyen Thao T. T.、Kawana-Tachikawa Ai、Inukai Takeshi、Takaori-Kondo Akifumi
    • Journal Title

      ImmunoHorizons

      Volume: 5 Issue: 8 Pages: 687-702

    • DOI

      10.4049/immunohorizons.2100054

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08812, KAKENHI-PROJECT-19H03615
  • [Journal Article] APOBEC3B reporter myeloma cell lines identify DNA damage response pathways leading to APOBEC3B expression2020

    • Author(s)
      Yamazaki Hiroyuki、Shirakawa Kotaro、Matsumoto Tadahiko、Kazuma Yasuhiro、Matsui Hiroyuki、Horisawa Yoshihito、Stanford Emani、Sarca Anamaria Daniela、Shirakawa Ryutaro、Shindo Keisuke、Takaori-Kondo Akifumi
    • Journal Title

      PLOS ONE

      Volume: 15 Issue: 1 Pages: e0223463-e0223463

    • DOI

      10.1371/journal.pone.0223463

    • NAID

      120006786934

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07342, KAKENHI-PROJECT-19H03502
  • [Journal Article] The MEK Inhibitor Trametinib Suppresses Major Histocompatibility Antigen-mismatched Rejection Following Pancreatic Islet Transplantation2020

    • Author(s)
      Seiichiro Tada, Takayuki Anazawa et al.
    • Journal Title

      Transplantation Direct

      Volume: 6 Issue: 9 Pages: e591-e591

    • DOI

      10.1097/txd.0000000000001045

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K08593, KAKENHI-PROJECT-19K08812
  • [Journal Article] Secondary failure of platelet recovery in patients treated with high-dose thiotepa and busulfan followed by autologous stem cell transplantation2020

    • Author(s)
      Wada Fumiya、Nishikori Momoko、Hishizawa Masakatsu、Watanabe Mitsumasa、Aiba Akiko、Kitano Toshiyuki、Shimazu Yayoi、Shindo Takero、Kondo Tadakazu、Takaori-Kondo Akifumi
    • Journal Title

      International Journal of Hematology

      Volume: 112 Issue: 5 Pages: 609-613

    • DOI

      10.1007/s12185-020-03007-4

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K08324, KAKENHI-PROJECT-19K08812
  • [Journal Article] Drug monitoring for mycophenolic acid in graft-versus-host disease prophylaxis in cord blood transplantation.2020

    • Author(s)
      Muranushi H, Kanda J, Arai Y, Shindo T, Hishizawa M, Yamamoto T, Kondo T, Yamashita K, Matsubara K, Takaori-Kondo A
    • Journal Title

      Br J Clin Pharmacol

      Volume: -

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K08812
  • [Journal Article] Alternative splicing of APOBEC3D generates functional diversity and its role as a DNA mutator2020

    • Author(s)
      Takei Hisashi、Fukuda Hirofumi、Pan Gilbert、Yamazaki Hiroyuki、Matsumoto Tadahiko、Kazuma Yasuhiro、Fujii Masanori、Nakayama Sohei、Kobayashi Ikei S.、Shindo Keisuke、Yamashita Riu、Shirakawa Kotaro、Takaori-Kondo Akifumi、Kobayashi Susumu S.
    • Journal Title

      International Journal of Hematology

      Volume: 112 Issue: 3 Pages: 395-408

    • DOI

      10.1007/s12185-020-02904-y

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K23930, KAKENHI-PROJECT-19H03502, KAKENHI-PROJECT-16K21746, KAKENHI-PROJECT-19K07591
  • [Journal Article] Drug monitoring for mycophenolic acid in graft‐ vs ‐host disease prophylaxis in cord blood transplantation2020

    • Author(s)
      Muranushi Hiroyuki、Kanda Junya、Arai Yasuyuki、Shindo Takero、Hishizawa Masakatsu、Yamamoto Takashi、Kondo Tadakazu、Yamashita Kohei、Matsubara Kazuo、Takaori‐Kondo Akifumi
    • Journal Title

      British Journal of Clinical Pharmacology

      Volume: 86 Issue: 12 Pages: 2464-2472

    • DOI

      10.1111/bcp.14354

    • NAID

      120006938957

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K17828, KAKENHI-PROJECT-19K08812
  • [Journal Article] Endogenous APOBEC3B Overexpression Constitutively Generates DNA Substitutions and Deletions in Myeloma Cells2019

    • Author(s)
      Yamazaki Hiroyuki、Shirakawa Kotaro、Matsumoto Tadahiko、Hirabayashi Shigeki、Murakawa Yasuhiro、Kobayashi Masayuki、Sarca Anamaria Daniela、Kazuma Yasuhiro、Matsui Hiroyuki、Maruyama Wataru、Fukuda Hirofumi、Shirakawa Ryutaro、Shindo Keisuke、Ri Masaki、Iida Shinsuke、Takaori-Kondo Akifumi
    • Journal Title

      Scientific Reports

      Volume: 9 Issue: 1 Pages: 7122-7122

    • DOI

      10.1038/s41598-019-43575-y

    • NAID

      120006629181

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07342, KAKENHI-PROJECT-19H03502
  • [Journal Article] Trametinib attenuates delayed rejection and preserves thymic function following rat lung transplantation2019

    • Author(s)
      150.Takahagi A, Shindo T, Chen-Yoshikawa TF, Yoshizawa A, Gochi F, Miyamoto E, Saito M, Tanaka S, MotoyamaH, Date H
    • Journal Title

      Am J Respir Cell Mol Biol.

      Volume: 印刷中 Issue: 3 Pages: 3550366-3550366

    • DOI

      10.1165/rcmb.2018-0188oc

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H02893, KAKENHI-PROJECT-19K08812
  • [Journal Article] Protein kinase A inhibits tumor mutator APOBEC3B through phosphorylation2019

    • Author(s)
      Matsumoto Tadahiko、Shirakawa Kotaro、Yokoyama Masaru、Fukuda Hirofumi、Sarca Anamaria Daniela、Koyabu Sukenao、Yamazaki Hiroyuki、Kazuma Yasuhiro、Matsui Hiroyuki、Maruyama Wataru、Nagata Kayoko、Tanabe Fumiko、Kobayashi Masayuki、Shindo Keisuke、Morishita Ryo、Sato Hironori、Takaori-Kondo Akifumi
    • Journal Title

      Scientific Reports

      Volume: 9 Issue: 1 Pages: 8307-8307

    • DOI

      10.1038/s41598-019-44407-9

    • NAID

      120006644044

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03502
  • [Journal Article] NET-CAGE characterizes the dynamics and topology of human transcribed cis-regulatory elements2019

    • Author(s)
      Hirabayashi Shigeki、Bhagat Shruti、Matsuki Yu、Takegami Yujiro、Uehata Takuya、Kanemaru Ai、Itoh Masayoshi、Shirakawa Kotaro、Takaori-Kondo Akifumi、Takeuchi Osamu、Carninci Piero、Katayama Shintaro、Hayashizaki Yoshihide、Kere Juha、Kawaji Hideya、Murakawa Yasuhiro
    • Journal Title

      Nature Genetics

      Volume: 51 Issue: 9 Pages: 1369-1379

    • DOI

      10.1038/s41588-019-0485-9

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H05278, KAKENHI-PROJECT-18H03992, KAKENHI-PROJECT-16H02902, KAKENHI-PROJECT-18K15185
  • [Journal Article] Observation by Real-Time NMR and Interpretation of Length- and Location-Dependent Deamination Activity of APOBEC3B2017

    • Author(s)
      Wan Li、Nagata Takashi、Morishita Ryo、Takaori-Kondo Akifumi、Katahira Masato
    • Journal Title

      ACS Chem Biol

      Volume: 12 Issue: 11 Pages: 2704-2708

    • DOI

      10.1021/acschembio.7b00662

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K07307, KAKENHI-PUBLICLY-16H00833, KAKENHI-PUBLICLY-17H05878, KAKENHI-PROJECT-26440026
  • [Journal Article] The Warburg-like regulation of PGAM in tumor.2015

    • Author(s)
      Taisuke Izumi, Takumi Mikawa, Hiroshi Kondoh, Matilde E LLeonart and Akifumi Takaori-Kondo.
    • Journal Title

      Trends in Cancer Research

      Volume: 10 Pages: 103-108

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26310103
  • [Journal Article] T memory stem cells are the hierarchical apex of adult T-cell leukemia2015

    • Author(s)
      Nagai Y, Kawahara M, Hishizawa M, Shimazu Y, Sugino N, Fujii S, Kadowaki N, Takaori-Kondo A
    • Journal Title

      Blood

      Volume: 125 Issue: 23 Pages: 3527-3535

    • DOI

      10.1182/blood-2014-10-607465

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K09501, KAKENHI-PLANNED-24115004, KAKENHI-PROJECT-26860729
  • [Journal Article] Dysregulated glycolysis as an oncogenic event.2015

    • Author(s)
      Takumi Mikawa, Matilde E LLeonart, Akifumi Takaori-Kondo, Nobuya Inagaki, Masayuki Yokode, and Hiroshi Kondoh
    • Journal Title

      Cell. Mol. Life Sci.

      Volume: 72 Issue: 10 Pages: 1881-92

    • DOI

      10.1007/s00018-015-1840-3

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25670350, KAKENHI-PROJECT-26310103
  • [Journal Article] Abacavir, an anti–HIV-1 drug, targets TDP1-deficient adult T cell leukemia.2015

    • Author(s)
      Tada K, Kobayashi M, Takiuchi Y, Iwai F, Sakamoto T, Nagata K, Shinohara M, Io K, Shirakawa K, Hishizawa M, Shindo K, Kadowaki N, Hirota K, Yamamoto J, Iwai S, Sasanuma H, Takeda S, Takaori-Kondo A.
    • Journal Title

      Science Advances

      Volume: 1 Issue: 3 Pages: 1-9

    • DOI

      10.1126/sciadv.1400203

    • NAID

      120005601014

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-24115004, KAKENHI-PUBLICLY-26116518, KAKENHI-PROJECT-23221005, KAKENHI-PROJECT-25281021
  • [Journal Article] ASK1 restores the antiviral activity of APOBEC3G by disrupting HIV-1 Vif-mediated counteraction.2015

    • Author(s)
      Miyakawa K, Matsunaga S, Kanou K, Matsuzawa A, Morishita R, Kudoh A, Shindo K, Yokoyama M, Sato H, Kimura H, Tamura T, Yamamoto N, Ichijo H, Takaori-Kondo A, Ryo A.
    • Journal Title

      Nature Communications

      Volume: 6:6945 Issue: 1 Pages: 6945-6945

    • DOI

      10.1038/ncomms7945

    • NAID

      120005745628

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24390115, KAKENHI-PROJECT-26860306, KAKENHI-PLANNED-24115004
  • [Journal Article] Quantitative analysis of location- and sequence-dependent deamination by APOBEC3G using real-time NMR spectroscopy2014

    • Author(s)
      Furukawa A, Sugase K, Morishita R, Nagata T, Kodaki T, Takaori-Kondo A, Ryo A, Katahira M
    • Journal Title

      Angew Chem Int Ed Engl

      Volume: 53(9) Pages: 2349-52

    • Data Source
      KAKENHI-PROJECT-23390110
  • [Journal Article] Uric acid induces NADPH oxidase-independent neutrophil extracellular trap formation2014

    • Author(s)
      Arai Y, Nishinaka Y, Arai T, Morita M, Mizugishi K, Adachi S, Takaori-Kondo A, Watanabe T, Yamashita K
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 443(2) Pages: 556-61

    • Data Source
      KAKENHI-PROJECT-23390110
  • [Journal Article] Lack of Association between Intact/Deletion Polymorphisms of the APOBEC3B Gene and HIV-1 Risk2014

    • Author(s)
      Imahashi M, Izumi T, Watanabe D, Imamura J, Matsuoka K, Ode H, Masaoka T, Sato K, Kaneko N, Ichikawa S, Koyanagi Y, Takaori-Kondo A, Utsumi M, Yokomaku Y, Shirasaka T, Sugiura W, Iwatani Y, Naoe T
    • Journal Title

      PLOS ONE

      Volume: 9(3)

    • Data Source
      KAKENHI-PROJECT-23390110
  • [Journal Article] Defining HIV-1 Vif residues that interact with CBFβ by site-directed mutagenesis.2014

    • Author(s)
      Matsui Y, Shindo K, Nagata K, Io K, Tada K, Iwai F, Kobayashi M, Kadowaki N, Harris R, Takaori-Kondo A
    • Journal Title

      Virology

      Volume: 449 Pages: 82-87

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-24115004
  • [Journal Article] Senescence-inducing stress promotes proteolysis of phosphoglycerate mutase via ubiquitin ligase Mdm22014

    • Author(s)
      Mikawa T, Maruyama T, Okamoto K, Nakagama H, Lleonart ME, Tsusaka T, Hori K, Murakami I, Izumi T, Takaori-Kondo A, Yokode M, Peters G, Beach D, Kondoh H
    • Journal Title

      J Cell Biol

      Volume: 204(5) Pages: 729-45

    • Data Source
      KAKENHI-PROJECT-23390110
  • [Journal Article] CKIP-1 Is an Intrinsic Negative Regulator of T-Cell Activation through an Interaction with CARMA1.2014

    • Author(s)
      Sakamoto T, Kobayashi M, Tada K, Shinohara M, Io K, Nagata K, Iwai F, Takiuchi Y, Arai Y, Yamashita K, Shindo K, Kadowaki N, Koyanagi Y, Takaori-Kondo A
    • Journal Title

      PLoS One

      Volume: 9 Issue: 1 Pages: 1-11

    • DOI

      10.1371/journal.pone.0085762

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390110, KAKENHI-PROJECT-23591383, KAKENHI-PROJECT-23591474, KAKENHI-PLANNED-24115004, KAKENHI-PLANNED-24115008
  • [Journal Article] Quantitative analysis of location- and sequence-dependent deamination by APOBEC3G using real-time NMR spectroscopy2014

    • Author(s)
      Furukawa, A., Sugase, K., Morishita, R., Nagata, T., Kodaki, T., Takaori-Kondo, A., Ryo, A., Katahira, M.
    • Journal Title

      Angew. Chem. Int. Ed. Engl.

      Volume: 53 Issue: 9 Pages: 2349-2352

    • DOI

      10.1002/anie.201309940

    • NAID

      120005647511

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-21113003, KAKENHI-PROJECT-23390110, KAKENHI-PROJECT-23570146, KAKENHI-PUBLICLY-24113710, KAKENHI-PUBLICLY-24121714, KAKENHI-PROJECT-24390115, KAKENHI-PUBLICLY-25115507, KAKENHI-PROJECT-25650056, KAKENHI-PUBLICLY-26104520, KAKENHI-PROJECT-26840040
  • [Journal Article] Quantitative Analysis of Location- and Sequence-Dependent Deamination by APOBEC3G Using Real-Time NMR Spectroscopy.2014

    • Author(s)
      Furukawa A, Sugase K, Morishita R, Nagata T, Kodaki T, Takaori-Kondo A, Ryo A, Katahira M.
    • Journal Title

      Angew Chem Int Ed Engl.

      Volume: 53 Pages: 2349-2352

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-24115004
  • [Journal Article] Lack of Association between Intact/Deletion Polymorphisms of the APOBEC3B Gene and HIV-1 Risk.2014

    • Author(s)
      Imahashi M, Izumi T, Watanabe D, Imamura J, Matsuoka K, Ode H, Masaoka T, Sato K, Kaneko N, Ichikawa S, Koyanagi Y, Takaori-Kondo A, Utsumi M, Yokomaku Y, Shirasaka T, Sugiura W, Iwatani Y, Naoe T.
    • Journal Title

      PLoS ONE

      Volume: 9 Pages: 1-9

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-24115004
  • [Journal Article] Defining HIV-1 Vif residues that interact with CBF by site-directed mutagenesis.2014

    • Author(s)
      Matsui Y, Shindo K, Nagata K, Io K, Tada K, Iwai F, Kobayashi M, Kadowaki N, Harris R, Takaori-Kondo A
    • Journal Title

      Virology

      Volume: 449 Pages: 82-87

    • DOI

      10.1016/j.virol.2013.11.004

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390110, KAKENHI-PROJECT-23591383
  • [Journal Article] Antitumor effects of bevacizumab in a microenvironment-dependent human adult T-cell leukemia/lymphoma mouse model2014

    • Author(s)
      Mori F, Ishida T, Ito A, Sato F, Masaki A, Narita T, Suzuki S, Yamada T, Takino H, Ri M, Kusumoto S, Komatsu H, Hishizawa M, Imada K, Takaori-Kondo A, Niimi A, Ueda R, Inagaki H, Iida S
    • Journal Title

      Eur J Haematol

      Volume: 92(3) Pages: 219-28

    • Data Source
      KAKENHI-PROJECT-23390110
  • [Journal Article] Defining HIV-1 Vif residues that interact with CBFbeta by site-directed mutagenesis2014

    • Author(s)
      Matsui Y, Shindo K, Nagata K, Io K, Tada K, Iwai F, Kobayashi M, Kadowaki N, Harris RS, Takaori-Kondo A
    • Journal Title

      Virology

      Volume: 449 Pages: 82-7

    • Data Source
      KAKENHI-PROJECT-23390110
  • [Journal Article] Lack of Association between Intact/Deletion Polymorphisms of the APOBEC3B Gene and HIV-1 Risk.2014

    • Author(s)
      Imahashi M, Izumi T, Watanabe D, Imamura J, Matsuoka K, Ode H, Masaoka T, Sato K, Kaneko N, Ichikawa S, Koyanagi Y, Takaori-Kondo A, Utsumi M, Yokomaku Y, Shirasaka T, Sugiura W, Iwatani Y, Naoe T.
    • Journal Title

      PLoS One

      Volume: 9 Issue: 3 Pages: e92861-e92861

    • DOI

      10.1371/journal.pone.0092861

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390110, KAKENHI-PLANNED-24115008, KAKENHI-PROJECT-24590568
  • [Journal Article] RING-mutant Mdm2-M459I Confers Anti-apoptotic Effect in Primary Cells2014

    • Author(s)
      9)Takumi Mikawa, Matilde E LLeonart, Akifumi Takaori-Kondo, Masayuki Yokode, and Hiroshi Kondoh
    • Journal Title

      Journal of Cytology & Histology

      Volume: 5 Issue: 06

    • DOI

      10.4172/2157-7099.1000i103

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26310103
  • [Journal Article] Small molecules that inhibit Vif-induced degradation of APOBEC3G.2014

    • Author(s)
      2.Matsui M, Shindo K, Izumi T, Io K, Shinohara M, Komano J, Kobayashi M, Kadowaki N, Harris RS, Takaori-Kondo A
    • Journal Title

      Virology Journal

      Volume: 11 Issue: 1 Pages: 122-129

    • DOI

      10.1186/1743-422x-11-122

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PLANNED-24115004
  • [Journal Article] APOBEC3D and APOBEC3F Potently Promote HIV-1 Diversification and Evolution in Humanized Mouse Model.2014

    • Author(s)
      4.Sato K, Takeuchi JS, Misawa N, Izumi T, Kobayashi T, Kimura Y, Iwami S, Takaori-Kondo A, Hu WS, Aihara K, Ito M, An DS, Pathak VK, Koyanagi Y
    • Journal Title

      PLoS Pathogens

      Volume: 10 Pages: 1-15

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-24115004
  • [Journal Article] CKIP-1 is an intrinsic negative regulator of T-cell activation through an interaction with CARMA12014

    • Author(s)
      Sakamoto T, Kobayashi M, Tada K, Shinohara M, Io K, Nagata K, Iwai F, Takiuchi Y, Arai Y, Yamashita K, Shindo K, Kadowaki N, Koyanagi Y, Takaori-Kondo A
    • Journal Title

      PLOS ONE

      Volume: 9(1)

    • Data Source
      KAKENHI-PROJECT-23390110
  • [Journal Article] Posttranscriptional Regulation of Glycolytic enzyme Phosphoglycerate Mutase.2014

    • Author(s)
      4)Takumi Mikawa, Koji Okamoto, Matilde E LLeonart, Akifumi Takaori-Kondo, Masayuki Yokode, Nobuya Inagaki , and Hiroshi Kondoh
    • Journal Title

      Science Proceedings

      Volume: 1

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26310103
  • [Journal Article] HIV-1 Vif : a guardian of the virus that opens up a new era in the research field of restriction factors2013

    • Author(s)
      Takaori-Kondo A, Shindo K
    • Journal Title

      Front Microbiol

      Volume: 4 Pages: 34-34

    • NAID

      120005244663

    • Data Source
      KAKENHI-PROJECT-23390110
  • [Journal Article] Human CD1c+ Myeloid Dendritic Cells Acquire a High Level of Retinoic Acid-Producing Capacity in Response to Vitamin D32013

    • Author(s)
      Sato T, Kitawaki T, Fujita H, Iwata M, Iyoda T, Inaba K, Ohteki T, Hasegawa S, Kawada K, Sakai Y, Ikeuchi H, Nakase H, Niwa A, Takaori-Kondo A, Kadowaki N
    • Journal Title

      J Immunol

      Volume: 191(6) Pages: 3152-60

    • Data Source
      KAKENHI-PROJECT-23390110
  • [Journal Article] Direct binding of Grb2 has an important role in the development of myeloproliferative disease induced by ETV6/FLT32013

    • Author(s)
      Chonabayashi K, Hishizawa M, Kawamata S, Nagai Y, Ohno T, Ishikawa T, Uchiyama T, Takaori-Kondo A
    • Journal Title

      Leukemia

      Volume: 27(6) Pages: 1433-6

    • Data Source
      KAKENHI-PROJECT-23390110
  • [Journal Article] Human CD1c+ myeloid dendritic cells acquire a high level of retinoic acid-producing capacity in response to vitamin D3.2013

    • Author(s)
      Sato T, Kitawaki T, Fujita H, Iwata M, Iyoda T, Inaba K, Ohteki T, Hasegawa S, Kawada K, Sakai Y, Ikeuchi H, Nakase H, Niwa A, Takaori-Kondo A, Kadowaki N
    • Journal Title

      Journal Immunology

      Volume: 191 Pages: 3152-3160

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-24115004
  • [Journal Article] Human herpesvirus-6 encephalitis during hematopoietic stem cell transplantation leads to poor prognosis2013

    • Author(s)
      Shimazu Y, Kondo T, Ishikawa T, Yamashita K, Takaori-Kondo A
    • Journal Title

      Transpl Infect Dis

      Volume: 15(2) Pages: 195-201

    • Data Source
      KAKENHI-PROJECT-23390110
  • [Journal Article] The tyrosine kinase inhibitor dasatinib suppresses cytokine production by plasmacytoid dendritic cells by targeting endosomal transport of CpG DNA2013

    • Author(s)
      Fujita H, Kitawaki T, Sato T, Maeda T, Kamihira S, Takaori-Kondo A, Kadowaki N
    • Journal Title

      Eur J Immunol

      Volume: 43(1) Pages: 93-103

    • Data Source
      KAKENHI-PROJECT-23390110
  • [Journal Article] HIV-1 Vif: a guardian of the virus that opens up a new era in the research field of restriction factors.2013

    • Author(s)
      Takaori-Kondo A
    • Journal Title

      Front Microbiol

      Volume: 4 Pages: 34-34

    • NAID

      120005244663

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390110
  • [Journal Article] Human CD1c^+ myeloid dendritic cells acquire a high level of retinoic acid-producing capacity in response to vitamin D_32013

    • Author(s)
      Sato T, Kitawaki T, Fujita H, Iwata M, Iyoda T, Inaba K, Ohteki T, Hasegawa S, Kawada K, Sakai Y, Ikeuchi H, Nakase H, Niwa A, Takaori-Kondo A, and Kadowaki N
    • Journal Title

      J Immunol

      Volume: 191(6) Issue: 6 Pages: 3152-3160

    • DOI

      10.4049/jimmunol.1203517

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390023, KAKENHI-PROJECT-23390110, KAKENHI-ORGANIZER-24111001
  • [Journal Article] HIV-1 Vif: a guardian of the virus that opens up a new era in the research field of restriction factors2013

    • Author(s)
      Takaori-Kondo A
    • Journal Title

      Frontier in Microbiology

      Volume: 4 Pages: 1-5

    • DOI

      10.3389/fmicb.2013.00034

    • NAID

      120005244663

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-24115004
  • [Journal Article] APOBEC3B can impair genomic stability by inducing base substitutions in genomic DNA in human cells2012

    • Author(s)
      Shinohara M, Io K, Shindo K, Matsui M, Sakamoto T, Tada K, Kobayashi M, Kadowaki N, Takaori-Kondo A
    • Journal Title

      Sci Rep

      Volume: 2 Pages: 806-806

    • Data Source
      KAKENHI-PROJECT-23390110
  • [Journal Article] NMR study of xenotropic murine leukemia virus-related virus protease in a complex with amprenavir2012

    • Author(s)
      Furukawa A, Okamura H, Morishita R, Matsunaga S, Kobayashi N, Ikegami T, Kodaki T, Takaori-Kondo A, Ryo A, Nagata T, Katahira M
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 425(2) Pages: 284-9

    • Data Source
      KAKENHI-PROJECT-23390110
  • [Journal Article] Molecular and enzymatic characterization of XMRV protease by a cell-free proteolytic analysis2012

    • Author(s)
      Matsunaga S, Sawasaki T, Ode H, Morishita R, Furukawa A, Sakuma R, Sugiura W, Sato H, Katahira M, Takaori-Kondo A, Yamamoto N, Ryo A
    • Journal Title

      J Proteomics

      Volume: 75(15) Pages: 4863-73

    • Data Source
      KAKENHI-PROJECT-23390110
  • [Journal Article] APOBEC3ファミリー蛋白2008

    • Author(s)
      高折 晃史
    • Journal Title

      日本エイズ学会誌 10

      Pages: 19-24

    • NAID

      10017102577

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590449
  • [Journal Article] APOBEC Family Proteins : Novel Antiviral Innate Immunity2006

    • Author(s)
      Akufumi, Takaori-Kondo
    • Journal Title

      Int J Hematol 83

      Pages: 213-216

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590449
  • [Journal Article] APOBEC Family Proteins : Novel Antiviral Innate Immunity.2006

    • Author(s)
      Akufumi Takaori-Kondo
    • Journal Title

      Int J Hematol 83・3

      Pages: 213-216

    • Data Source
      KAKENHI-PROJECT-18590449
  • [Journal Article] APOBEC Family Proteins: Novel Antiviral Innate Immunity.2006

    • Author(s)
      Akufumi Takaori-Kondo
    • Journal Title

      Int J Hematol 83

      Pages: 213-216

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590449
  • [Presentation] The MEK inhibitor cobimetinib suppresses lung GVHD through inhibition of B cells and monocytes.2021

    • Author(s)
      Muranushi H, Shindo T, Ngo HT, Gochi F, Yoshizawa A, Yoshikawa T, Takaori-Kondo A.
    • Organizer
      第83回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-19K08812
  • [Presentation] Dual Inhibition of the MEK/ERK and PI3K/AKT Pathways Prevents Pulmonary Graft-Versus-Host Disease through Suppression of Arteriovenous Inflammation and Bronchiolitis2021

    • Author(s)
      Hiroyuki Muranushi, Takero Shindo, Huong Thi Ngo, Fumiaki Gochi, Akihiko Yoshizawa, Toyofumi Fengshi Chen-Yoshikawa, and Akifumi Takaori-Kondo.
    • Organizer
      The 63rd Annual Meeting of the American Society of Hematology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K08812
  • [Presentation] KIR3DL1 allotype-dependent modulation of NK cell immunity against chronic myeloid leukemia.2021

    • Author(s)
      Izumi K, Shindo T, Ngo HT, Nakayama-Hosoya K, Akahane K, Tamai M, Nguyen TT, Kawana-Tachikawa A, Inukai T, Takaori-Kondo A.
    • Organizer
      第83回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-19K08812
  • [Presentation] シトシン脱アミノ化酵素APOBEC3Bの活性はILF2とhnRNPA1により亢進する2021

    • Author(s)
      数馬安浩, 白川康太郎, 小西義延, 松井宏行, 松本忠彦, 高折晃史
    • Organizer
      第80回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-19H03502
  • [Presentation] The MEK inhibitor cobimetinib ameliorates bronchiolitis obliterans after hematopoietic stem cell transplantation.2020

    • Author(s)
      Muranushi H, Shindo T, Huong Ngo Thi, Gochi F, Yoshizawa A, Toyofumi Chen-Yoshikawa, Akifumi Takaori-Kondo.
    • Organizer
      第12回日本血液疾患免疫療法学会学術集会
    • Data Source
      KAKENHI-PROJECT-19K08812
  • [Presentation] High-dose thiotepa and busulfan with ASCT in CNS lymphoma -DSP1958 Expanded Access Program #3/4.2020

    • Author(s)
      Wada F, Nishikori M, Hishizawa M, Watanabe M, Aiba A, Kitano T, Shimazu Y, Shindo T, Kondo T, Takaori-Kondo A.
    • Organizer
      第82回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-19K08812
  • [Presentation] シトシン脱アミノ化酵素APOBEC3Bの相互作用蛋白の同定と機能的解析.2019

    • Author(s)
      数馬安浩, 白川康太郎, 松井宏行, 山崎寛章, 松本忠彦, 伊藤慎二, 高折晃史
    • Organizer
      第78回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-19H03502
  • [Presentation] The MEK Inhibitor Trametinib Enhances Diverse T Cell Reconstitution with Suppressing Xenogeneic Graft-Versus-Host-Disease2019

    • Author(s)
      Hidekazu Itamura, Hiroyuki Muranushi, Takero Shindo, Kazutaka Kitaura, Seiji Okada, Tadasu Shin-I, Ryuji Suzuki, Akifumi Takaori-Kondo, Shinya Kimura
    • Organizer
      The 62nd Annual Meeting of the American Society of Hematology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K08812
  • [Presentation] MEK inhibitor trametinib enhances diverse T cell reconstitution with suppressing xenogeneic GVHD2019

    • Author(s)
      Hiroyuki Muranushi, Hidekazu Itamura, Takero Shindo, Kazutaka Kitaura, Seiji Okada, Tadasu Shin-I, Ryuji Suzuki, Akifumi Takaori-Kondo, Shinya Kimura
    • Organizer
      The 81st Annual Meeting of the Japanese Society of Hematology
    • Data Source
      KAKENHI-PROJECT-19K08812
  • [Presentation] がんの内在性変異源APOBEC3Bの非コードRNAに結合能力はレトロエレメントを阻害に必要である.2019

    • Author(s)
      松本忠彦, 白川康太郎, 小薮助直, 数馬安浩, 山崎寛章, 松井宏行, 高折晃史
    • Organizer
      第78回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-19H03502
  • [Presentation] Tumor mutaor APOBEC3B binds to cellular non-coding RNAs to inhibit retroelements.2019

    • Author(s)
      松本忠彦, 白川康太郎, 小薮助直, Sarca AD, Stanford E, 福田寛文, 松井宏行, 山崎寛章, 数馬安浩, 堀澤欣史, 高折晃史
    • Organizer
      第33回日本エイズ学会学術集会
    • Data Source
      KAKENHI-PROJECT-19H03502
  • [Presentation] Characterization of the deamination activity of APOBEC3B by real-time NMR, which is distinct from that of APOBEC3G2017

    • Author(s)
      Li Wan, Takashi Nagata, Ryo Morishita, Akifumi Takaori-Kondo, Masato Katahira
    • Organizer
      7th Asia-Pacific NMR Symposium
    • Place of Presentation
      Indian Institute of Science (Bangalore)
    • Year and Date
      2017-02-16
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26440026
  • [Presentation] Characterization of the cytidine deamination properties of human APOBEC3B by real-time NMR, which are quite different from those of APOBEC3G2017

    • Author(s)
      Li Wan, Takashi Nagata, Ryo Morishita, Akifumi Takaori-Kondo, Masato Katahira
    • Organizer
      The 44th International Symposium on Nucleic Acids Chemistry, The 1st Annual Meeting of Japan Society of Nucleic Acids Chemistry
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26440026
  • [Presentation] Characterization of the deamination activity of APOBEC3B by real-time NMR, which is distinct from that of APOBEC3G2016

    • Author(s)
      Li Wan, Takashi Nagata, Ryo Morishita, Akifumi Takaori-Kondo, Masato Katahira
    • Organizer
      第54回日本生物物理学会年会
    • Place of Presentation
      つくば国際会議場(つくば市
    • Year and Date
      2016-11-25
    • Data Source
      KAKENHI-PROJECT-26440026
  • [Presentation] 抗HIV-1宿主因子APOBEC3GとHIV-1 Vif2007

    • Author(s)
      高折 晃史
    • Organizer
      第21回日本エイズ学会学術集会
    • Place of Presentation
      広島
    • Year and Date
      2007-11-28
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590449
  • [Presentation] Induction of ubiquitination and degradation of HIV-1 Vif by MDM2.2007

    • Author(s)
      Akifumi Takaori-kondo, et. al.
    • Organizer
      The 2007 meeting on RETROVIRUSES, Cold Spring Harbor Laboratory
    • Place of Presentation
      Cold Spring Harbor
    • Data Source
      KAKENHI-PROJECT-19041033
  • [Presentation] Induction of ubiquitination and degradation of HIV-1 Vifby MDM2.2007

    • Author(s)
      Akifumi Takaori-kondo, et. al.
    • Organizer
      The 2007 meeting on RETROVIRUSES, Cold Spring Harbor Laboratory
    • Place of Presentation
      Cold Spring Harbor
    • Data Source
      KAKENHI-PROJECT-18590449
  • [Presentation] Induction of ubiquitination and degradation of HIV-1 Vif by MDM2.2007

    • Author(s)
      Akifumi Takaori-Kondo
    • Organizer
      The 2007 meeting on RETROVIRUSES, Cold Spring Harbor Laboratory
    • Place of Presentation
      Cold Spring Harbor
    • Year and Date
      2007-05-22
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590449
  • [Presentation] Regulation of HIV-1 replication by APOBEC3G/Vif2007

    • Author(s)
      Akifumi, Takaori-Kondo
    • Organizer
      The 21th annual meeting of the Japanese Society for AIDS Research
    • Place of Presentation
      Hiroshima
    • Year and Date
      2007-11-28
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590449
  • [Presentation] Induction of Vif ubiquitination and degradation by MDM22007

    • Author(s)
      Akifumi, Takaori-Kondo
    • Organizer
      The 2007 meeting on RETROVIRUSES, Cold Spring Harbor Laboratory
    • Place of Presentation
      Cold Spring Harbor
    • Year and Date
      2007-05-22
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590449
  • [Presentation] APOBEC3G/VifによるHIV-1の複製制御2007

    • Author(s)
      高折 晃史
    • Organizer
      第21回日本エイズ学会学術集会
    • Place of Presentation
      広島
    • Year and Date
      2007-11-28
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590449
  • [Presentation] Anti-HIV-1 host factor APOBEC3G and HIV-1 Vif2007

    • Author(s)
      Akifumi, Takaori-Kondo
    • Organizer
      The 21th annual meeting of the Japanese Society for AIDS Research
    • Place of Presentation
      Hiroshima
    • Year and Date
      2007-11-28
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590449
  • [Presentation] Murine retrovirus escapes from murine APOBEC3 via 2 distinct novel mechanisms2006

    • Author(s)
      Akifumi, Takaori-Kondo
    • Organizer
      The 2006 meeting on RETROVIRUSES, Cold Spring Harbor Laboratory
    • Place of Presentation
      Cold Spring Harbor
    • Year and Date
      2006-05-23
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590449
  • [Presentation] Murine retrovirus escapes from murine APOBEC3 via 2 distinct novel mechanisms.2006

    • Author(s)
      Akifumi Takaori-Kondo
    • Organizer
      The 2006 meeting on RETROVIRUSES, Cold Spring Harbor Laboratory
    • Place of Presentation
      Cold Spring Harbor
    • Year and Date
      2006-05-23
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590449
  • []

  • 1.  KOYANAGI Yoshio (80215417)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 4 results
  • 2.  KONDOH Hiroshi (80402890)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 4 results
  • 3.  SUGITA Masahiko (80333532)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  YOKODE Masayuki (20252447)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 5.  Fujita Takashi (10156870)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 6.  Murakawa Yasuhiro (50765469)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 7.  白川 康太郎 (80728270)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 7 results
  • 8.  OKAMOTO Koji (80342913)
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  • 9.  SOGA Tomoyoshi (60338217)
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  • 10.  TANAKA Tomoaki (50447299)
    # of Collaborated Projects: 1 results
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  • 11.  KATO Hiroki (10597173)
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  • 12.  SHINDO Keisuke (10602344)
    # of Collaborated Projects: 1 results
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  • 13.  UCHIYAMA Takashi (80151900)
    # of Collaborated Projects: 1 results
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  • 14.  MATSUSHITA Shuzo (00199788)
    # of Collaborated Projects: 1 results
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  • 15.  MITUYA Yoshiaki (20136724)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  HORI Toshiyuki (70243102)
    # of Collaborated Projects: 1 results
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  • 17.  OGAWA SEISHI (60292900)
    # of Collaborated Projects: 1 results
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  • 18.  Nakao Shinji (70217660)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  NAGATA Kyosuke (40180492)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  Park Sam-Yong (20291932)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  Takeyasu Kunio (40135695)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  Arase Hisashi (10261900)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  Iba Hideo (60111449)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  Nagata Takashi (10415250)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 25.  KATAHIRA Masato (60265717)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  Shindo Takero (10646706)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 14 results
  • 27.  永井 美之 (20022874)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  脇田 隆字 (40280789)
    # of Collaborated Projects: 1 results
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  • 29.  柳 雄介 (40182365)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  小池 智 (30195630)
    # of Collaborated Projects: 1 results
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  • 31.  夏目 徹 (00357683)
    # of Collaborated Projects: 1 results
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  • 32.  佐々木 顕 (90211937)
    # of Collaborated Projects: 1 results
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  • 33.  伊村 明浩 (60362513)
    # of Collaborated Projects: 1 results
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  • 34.  三浦 康生 (70605146)
    # of Collaborated Projects: 1 results
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  • 35.  島津 裕 (40706777)
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  • 36.  藤井 紀恵 (50834058)
    # of Collaborated Projects: 1 results
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  • 37.  CHIN Toyofumi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 38.  DATE Hiroshi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 39.  ANAZAWA Takayuki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 40.  NISHIKORI Momoko
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 41.  白川 龍太郎
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 42.  吉澤 明彦
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 43.  菅瀬 謙治
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 44.  門脇 則光
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 45.  高橋 栄夫
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results
  • 46.  竹内 理
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 47.  植畑 拓也
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 48.  藤井 昌学
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 49.  岩田 誠
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 50.  梁 明秀
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 51.  新井 康之
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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