Yamashita Akio 山下暁朗

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YAMASHITA Akio 山下暁朗

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Researcher Number	20405020
Other IDs
Affiliation (Current)	2025: 近畿大学, 薬学部, 教授 2025: 琉球大学, 医学(系)研究科(研究院), 教授
Affiliation (based on the past Project Information) *help	2020 – 2024: 琉球大学, 医学(系)研究科(研究院), 教授 2021 – 2022: 横浜市立大学, 医学部, 准教授 2020 – 2022: 横浜市立大学, 医学研究科, 客員教授 2016 – 2019: 横浜市立大学, 医学部, 准教授 2015: 横浜市立大学医学部, 分子細胞生物学, 准教授 … More 2010 – 2015: 横浜市立大学, 医学部, 講師 2010: Yokohama City University, 医学研究科, 講師 2010: 横浜市立大学, 医学部・微生物学, 講師 2007 – 2009: Yokohama City University, 医学研究科, 客員准教授 2006 – 2007: 横浜市立大学, 医学研究科, COE特任教員 Less
Review Section/Research Field	Principal Investigator Molecular biology / Basic Section 48040:Medical biochemistry-related / Biological Sciences / Medium-sized Section 50:Oncology and related fields / Medium-sized Section 52:General internal medicine and related fields / General internal medicine and related fields / General medical chemistry Except Principal Investigator Basic Section 52010:General internal medicine-related / Basic Section 56040:Obstetrics and gynecology-related / Biological Sciences … More / Neurology / Obstetrics and gynecology / General internal medicine(including psychosomatic medicine) / Pathological medical chemistry / Cell biology Less
Keywords	Principal Investigator mRNA分解 / NMD / ナンセンス変異 / mRNA監視機構 / mRNA翻訳 / 遺伝性疾患 / 翻訳終結 / mRNA代謝 / がん抗原 / SMG1 … More / 新生鎖 / モデルマウス / 嚢胞性線維症 / mRNA decay / nonsense mutation / 生体分子 / 核酸 / シグナル伝達 / 遺伝子 / 翻訳 / 制御 / 再編 / 転写装置 / 遺伝情報複製 / 細胞ストレス応答 / ナンセンスコドン / フレームシフト変異 / ストレス応答 / シャペロン / キナーゼ / mRNA翻訳制御 / mRNA分解制御 / 新生ポリペプチド / リボソーム / ストレス / TRAP法 / アミノ酸飢餓 / 転写後制御 / 疾患モデルマウス / リードスルー / 希少疾患 / 薬剤スクリーニングシステム / screening / small compound / translation / 転写五兆節 / 酵素 / 統合的ストレス応答 / タンパク質翻訳 / 転写後調節 / がん / 細胞医化学 … More Except Principal Investigator siRNA / 高血圧 / 受容体 / HPV / NMD抑制 / virus-cell interaction / CRISPR/Cas9 / レニン－アンジオテンシン系 / 慢性腎臓病 / レニンアンジオテンシン系 / 老化 / PTC / collagen VI / ゲノム / 核酸 / 発現制御 / 細胞増殖 / Nonsense-mediated mRNA decay(NMD) / NMD構成分子 / cell factor / レニンアンジオテンシン / 中枢神経 / 細胞必須因子 / 感染 / 動脈硬化 / 脳心血管病 / アンチエイジング / 糖尿病 / 新規治療 / 腎性老化 / 治療標的 / 病態解明 / 腎臓病・高血圧 / 情報伝達系 / 子宮頸癌 / 細胞受容体 / virus binding protein / トランスレーショナルリサーチ / 循環器・腎臓内科 / レニン-アンジオテンシン系 / サーチュイン / 腎線維化 / 心血管病 / ストレス蛋白質 / GAS5 / 早期終止コドン / Snhg1 / 蛋白質翻訳 / mTOR pathway / 小胞体ストレスプレコンディショニング / 早期終止コドン (PTC) / eIF2α リン酸化 / Snhg1 mRNA / 蛋白質翻訳抑制 / 早期終止コドン(PTC) / eIF2αリン酸化 / mRNA監視機構(NMD) / 環境ストレス / Ullrich's disease / molesular therapy / nonsense mutation / frame-shift mutation / hSMG-1 / hUpf1 / molecular therapy / collagenVI / Ullrich病 / premature translation termination codon(PTC) / nonsense-mediated mRNA decay(NMD) / 発生・文化 / 発生・分化 / 細胞・組織 / 分化 / 発生 / シグナル伝達 / 組織 / 細胞 / 再生医学 / 癌 / TNRC６A / RISC / RNA結合タンパク質 / miRNA / 小分子RNA / 非コードRNA / base-pairing / thermodynamics / PACT / TRBP / TNRC6A / microRNA / small interfering RNA / small RNA / 蛋白質 / 遺伝子 / SMG-7 / SMG-1 / Upf1 / グルタチオンペルオキシダーゼ1 / セレノプロテイン / セレノシステイン / nonsense-mediated mRNA decay NMD / SMG-8 / HeLa細胞 / ノックダウン / 生体ストレス応答 / 細胞生理機能 / 腫瘍細胞 / Ullrich病繊維芽細胞 / siRNA, NMD抑制 / Nonsense-mediated mRNA decay (NMD) Less

細胞ストレスによるmRNA監視機構抑制の分子機構とがん抗原発現機構の解明Principal Investigator
- Principal Investigator
  
  山下暁朗
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  University of the Ryukyus
Treatment of pathophysiological linkage between hypertension and kidney disease focusing on receptor binding factors in the central nervous system
- Principal Investigator
  
  涌井広道
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Yokohama City University
ゲノム編集技術を使用したヒトパピローマウイルスの感染機構に関する研究
- Principal Investigator
  
  島田勝
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Yokohama City University
Analysis of the inhibition of mRNA surveillancePrincipal Investigator
- Principal Investigator
  
  YAMASHITA AKIO
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 50:Oncology and related fields
- Research Institution
  University of the Ryukyus
A pathophysiological significance of receptor-binding factor in aging-associated cerebral cardiovascular disease
- Principal Investigator
  
  WAKUI Hiromichi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Yokohama City University
Elucidation of the cell infection mechanism of human papilloma virus using genome editing technique
- Principal Investigator
  
  SHIMADA Masaru
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Yokohama City University
Analysis of post-translation termination eventPrincipal Investigator
- Principal Investigator
  
  YAMASHITA AKIO
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  University of the Ryukyus
Development of basic technology for intractable and rare diseasesPrincipal Investigator
- Principal Investigator
  
  YAMASHITA AKIO
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 52:General internal medicine and related fields
- Research Institution
  University of the Ryukyus
  Yokohama City University
Therapeutic Strategy against Renal Aging via Novel Dual Actions of Receptor-binding Molecule
- Principal Investigator
  
  TAMURA Kouichi
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Yokohama City University
The pathophysiological significance of receptor-binding cardiovascular protective molecule in aging-associated cardiovascular diseases
- Principal Investigator
  
  Wakui Hiromichi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General internal medicine(including psychosomatic medicine)
- Research Institution
  Yokohama City University
A study for human papillomavirus (HPV) infection mechanism
- Principal Investigator
  
  Shimada Masaru
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Yokohama City University
Development of basic technology for intractable and rare diseasesPrincipal Investigator
- Principal Investigator
  
  Akio Yamashita
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  General internal medicine and related fields
- Research Institution
  Yokohama City University
Analysis of the nascent peptide-ribosome complex during amino acid starvation.Principal Investigator
- Principal Investigator
  
  山下暁朗
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Yokohama City University
Post-transcriptional gene expression regulation via mRNA surveillance systemPrincipal Investigator
- Principal Investigator
  
  YAMASHITA AKIO
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Molecular biology
- Research Institution
  Yokohama City University
Research on environmental stresses-induced change in nonsense-mediated mRNA decay (NMD) activity and its effect on pathological conditions
- Principal Investigator
  
  Usuki Fusako
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  National Institute for Minamata Disease
異常終止コドン認識複合体の構造機能解析Principal Investigator
- Principal Investigator
  
  山下暁朗
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Yokohama City University
Gene expression regulation via mRNA surveillance systemPrincipal Investigator
- Principal Investigator
  
  YAMASHITA Akio
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Molecular biology
- Research Institution
  Yokohama City University
Molecular mechanisms of the polarity-regulating signaling
- Principal Investigator
  
  OHNO Shigeo
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Cell biology
- Research Institution
  Yokohama City University
Functional machinery for non-coding RNAs
- Principal Investigator
  
  TOMARI Yukihide
- Project Period (FY)
  2009 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Regulation of functional machinery of small RNAs
- Principal Investigator
  
  UI-TEI Kumiko
- Project Period (FY)
  2009 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Analysis of mRNP complex using gene knockin in mammalian cellsPrincipal Investigator
- Principal Investigator
  
  YAMASHITA Akio
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Yokohama City University
Research on the pathophysiology and treatment of neurological disorders modified by nonsense-mediated mRNA decay (NMD)
- Principal Investigator
  
  USUKI Fusako
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  National Institute for Minamata Disease
Analysis of mRNP remodeling during NMDPrincipal Investigator
- Principal Investigator
  
  山下暁朗
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Molecular biology
- Research Institution
  Yokohama City University
Research on the therapeutic approach targeting an mRNA quality-control in herediatry neurological disorders
- Principal Investigator
  
  USUKI Fusako
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  National Institute for Minamata Disease

[Book] 実験医学 vol.30 No.92013
- Author(s)
  山下暁朗
- Total Pages
  10
- Publisher
  mRNA品質管理機構の最新理解と新たな標的治療の可能性
- Data Source
  KAKENHI-PROJECT-23687025
[Book] 横浜医学 2012年6月　30巻9号2012
- Author(s)
  山下暁朗
- Total Pages
  10
- Publisher
  羊土社
- Data Source
  KAKENHI-PLANNED-21115004
[Book] 横浜医学2012年1月63巻1号2012
- Author(s)
  山下暁朗
- Total Pages
  16
- Publisher
  横浜市立大学医学会
- Data Source
  KAKENHI-PROJECT-23687025
[Book] 横浜医学2012年1月63巻1号2012
- Author(s)
  山下暁朗
- Total Pages
  16
- Publisher
  横浜市立大学医学会
- Data Source
  KAKENHI-PUBLICLY-23112718
[Book] 実験医学 vol.30 No.92012
- Author(s)
  山下暁朗
- Total Pages
  10
- Publisher
  mRNA品質管理機構の最新理解と新たな標的治療の可能性
- Data Source
  KAKENHI-PUBLICLY-23112718
[Book] 横浜医学 2012年１月　６３巻１号2012
- Author(s)
  山下暁朗
- Total Pages
  16
- Publisher
  横浜市立大学医学会
- Data Source
  KAKENHI-PLANNED-21115004
[Book] 臨床検査2011年9月55巻9号2011
- Author(s)
  山下暁朗
- Total Pages
  6
- Publisher
  医学書院
- Data Source
  KAKENHI-PUBLICLY-23112718
[Book] 臨床検査2011年9月55巻9号2011
- Author(s)
  山下暁朗
- Total Pages
  6
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-23687025
[Book] 臨床検査　2011年9月　55巻9号2011
- Author(s)
  山下暁朗
- Total Pages
  6
- Publisher
  医学書院
- Data Source
  KAKENHI-PLANNED-21115004
[Book] 疾患との関わり.(mRNA surveillanceの分子機構と生命現象.) 28(10)2010
- Author(s)
  山下暁朗, 臼杵扶佐子.
- Publisher
  実験医学.
- Data Source
  KAKENHI-PROJECT-21790289
[Book] 実験医学増刊「拡大・進展を続けるRNA研究の最先端」(塩見春彦、塩見美喜子、稲田利文、廣瀬哲郎編集)2010
- Author(s)
  山下暁朗、臼杵扶佐子
- Total Pages
  205
- Publisher
  mRNA監視機構の生命現象、疾患への寄与とその分子機構
- Data Source
  KAKENHI-PROJECT-20591015
[Book] mRNA監視機構の生命現象、疾患への寄与とその分子機構.実験医学増刊「拡大・進展を続けるRNA研究の最先端」(塩見春彦、塩見美喜子、稲田利文、廣瀬哲郎編集)2010
- Author(s)
  山下暁朗、臼杵扶佐子
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-20591015
[Book] 実験医学2010
- Author(s)
  山下暁朗、臼杵扶佐子
- Publisher
  mRNA surveillanceの分子機構と生命現象、疾患との関わり
- Data Source
  KAKENHI-PROJECT-21790289
[Book] NMDによるmRNA排除と疾患-----難治性遺伝性疾患治療への試み.蛋白質・核酸・酵素増刊mRNAプログラム多様性と非対称性の獲得戦略(稲田利文、大野睦人編集)2009
- Author(s)
  山下暁朗、臼杵扶佐子
- Publisher
  共立出版, 東京
- Data Source
  KAKENHI-PROJECT-20591015
[Book] NMDと疾患.29(2)2009
- Author(s)
  臼杵扶佐子, 山下暁朗.
- Publisher
  細胞工学.
- Data Source
  KAKENHI-PROJECT-21790289
[Book] 54(16)2009
- Author(s)
  山下暁朗, 臼杵扶佐子.
- Publisher
  タンパク質核酸酵素.(mRNA品質管理システムと疾患)
- Data Source
  KAKENHI-PROJECT-21790289
[Journal Article] Effects of a High-Protein Diet on Kidney Injury under Conditions of Non-CKD or CKD in Mice2023
- Author(s)
  Shohei Tanaka, Hiromichi Wakui, Kengo Azushima, Shunichiro Tsukamoto, Takahiro Yamaji, Shingo Urate, Toru Suzuki, Eriko Abe, Shinya Taguchi, Takayuki Yamada, Ryu Kobayashi, Tomohiko Kanaoka, Daisuke Kamimura, Sho Kinguchi, Masahito Takiguchi, Kengo Funakoshi, Akio Yamashita, Tomoaki Ishigami, and Kouichi Tamura
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 24 Issue: 9 Pages: 7778-7778
- DOI
  10.3390/ijms24097778
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16247, KAKENHI-PROJECT-23K14741, KAKENHI-PROJECT-23K15252, KAKENHI-PROJECT-23K06871, KAKENHI-PROJECT-22K20861, KAKENHI-PROJECT-22K20890
[Journal Article] miR-125a-5p/miR-125b-5p contributes to pathological activation of angiotensin II-AT1R in mouse distal convoluted tubule cells by the suppression of Atrap2023
- Author(s)
  Hirota Keigo、Yamashita Akio、Abe Eriko、Yamaji Takahiro、Azushima Kengo、Tanaka Shohei、Taguchi Shinya、Tsukamoto Shunichiro、Wakui Hiromichi、Tamura Kouichi
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 299 Issue: 12 Pages: 105478-105478
- DOI
  10.1016/j.jbc.2023.105478
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K06871, KAKENHI-PROJECT-23K07678
[Journal Article] Simultaneous measurement of nascent transcriptome and translatome using 4-thiouridine metabolic RNA labeling and translating ribosome affinity purification2023
- Author(s)
  Imai Hirotatsu、Utsumi Daisuke、Torihara Hidetsugu、Takahashi Kenzo、Kuroyanagi Hidehito、Yamashita Akio
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 51 Issue: 14 Pages: e76-e76
- DOI
  10.1093/nar/gkad545
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08387, KAKENHI-PROJECT-23K08826, KAKENHI-PROJECT-21K15015, KAKENHI-PROJECT-20H03181, KAKENHI-PROJECT-22H04925
[Journal Article] Angiotensin II type 1 receptor-associated protein deletion combined with angiotensin II stimulation accelerates the development of diabetic kidney disease in mice on a C57BL/6 strain2023
- Author(s)
  Taguchi Shinya、Azushima Kengo、Yamaji Takahiro、Suzuki Toru、Abe Eriko、Tanaka Shohei、Hirota Keigo、Tsukamoto Shunichiro、Morita Ryutaro、Kobayashi Ryu、Kinguchi Sho、Yamashita Akio、Wakui Hiromichi、Tamura Kouichi
- Journal Title
  
  Hypertension Research
  
  Volume: 47 Issue: 1 Pages: 55-66
- DOI
  10.1038/s41440-023-01496-4
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K15252, KAKENHI-PROJECT-23K06871, KAKENHI-PROJECT-23K07678, KAKENHI-PROJECT-22K20890
[Journal Article] Angiotensin II type 1 receptor-associated protein in immune cells: a possible key factor in the pathogenesis of visceral obesity2023
- Author(s)
  Tsukamoto Shunichiro、Suzuki Toru、Wakui Hiromichi、Uehara Tatsuki、Ichikawa Juri、Okuda Hiroshi、Haruhara Kotaro、Azushima Kengo、Abe Eriko、Tanaka Shohei、Taguchi Shinya、Hirota Keigo、Kinguchi Sho、Yamashita Akio、Tamura Tomohiko、Tamura Kouichi
- Journal Title
  
  Metabolism
  
  Volume: 149 Pages: 155706-155706
- DOI
  10.1016/j.metabol.2023.155706
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K18129, KAKENHI-PROJECT-23K15252, KAKENHI-PROJECT-23K06871, KAKENHI-PROJECT-23K07678, KAKENHI-PROJECT-22K20890, KAKENHI-PROJECT-21H02954
[Journal Article] Combination of sacubitril/valsartan and blockade of the PI3K pathway enhanced kidney protection in a mouse model of cardiorenal syndrome2023
- Author(s)
  Tsukamoto Shunichiro、Wakui Hiromichi、Uehara Tatsuki、Shiba Yuka、Azushima Kengo、Abe Eriko、Tanaka Shohei、Taguchi Shinya、Hirota Keigo、Urate Shingo、Suzuki Toru、Yamada Takayuki、Kinguchi Sho、Yamashita Akio、Tamura Kouichi
- Journal Title
  
  European Heart Journal Open
  
  Volume: 3 Issue: 6 Pages: 1-13
- DOI
  10.1093/ehjopen/oead098
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K14741, KAKENHI-PROJECT-23K15252, KAKENHI-PROJECT-23K06871, KAKENHI-PROJECT-23K07678, KAKENHI-PROJECT-22K20861, KAKENHI-PROJECT-22K20890
[Journal Article] Angiotensin II type-1 receptor-associated protein interacts with transferrin receptor-1 and promotes its internalization2022
- Author(s)
  Abe Eriko、Yamashita Akio、Hirota Keigo、Yamaji Takahiro、Azushima Kengo、Urate Shingo、Suzuki Toru、Tanaka Shohei、Taguchi Shinya、Tsukamoto Shunichiro、Uehara Tatsuki、Wakui Hiromichi、Tamura Kouichi、Takahashi Hidehisa
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 17376-17376
- DOI
  10.1038/s41598-022-22343-5
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K20890, KAKENHI-PLANNED-21H05159, KAKENHI-PROJECT-21H02405, KAKENHI-PROJECT-20K07786, KAKENHI-PROJECT-20K09603, KAKENHI-PROJECT-21K19356, KAKENHI-PROJECT-21K16166
[Journal Article] Deficiency of the kidney tubular angiotensin II type1 receptor?associated protein ATRAP exacerbates streptozotocin-induced diabetic glomerular injury via reducing protective macrophage polarization2022
- Author(s)
  Haruhara Kotaro、Suzuki Toru、Wakui Hiromichi、Azushima Kengo、Kurotaki Daisuke、Kawase Wataru、Uneda Kazushi、Kobayashi Ryu、Ohki Kohji、Kinguchi Sho、Yamaji Takahiro、Kato Ikuma、Ohashi Kenichi、Yamashita Akio、Tamura Tomohiko、Tsuboi Nobuo、Yokoo Takashi、Tamura Kouichi
- Journal Title
  
  Kidney International
  
  Volume: 101 Issue: 5 Pages: 912-928
- DOI
  10.1016/j.kint.2022.01.031
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22601, KAKENHI-PROJECT-19K17575, KAKENHI-PROJECT-20K22908, KAKENHI-PROJECT-20H03438, KAKENHI-PROJECT-20K07786, KAKENHI-PROJECT-21K19413, KAKENHI-PROJECT-21K16166, KAKENHI-PROJECT-22K20890, KAKENHI-PROJECT-20K21606, KAKENHI-PROJECT-21H02954
[Journal Article] Distinct RNA polymerase transcripts direct the assembly of phase-separated DBC1 nuclear bodies in different cell lines2021
- Author(s)
  Mannen Taro、Goto Masato、Yoshizawa Takuya、Yamashita Akio、Hirose Tetsuro、Hayano Toshiya
- Journal Title
  
  Molecular Biology of the Cell
  
  Volume: 32 Issue: 21
- DOI
  10.1091/mbc.e21-02-0081
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22601, KAKENHI-PUBLICLY-20H05377, KAKENHI-PLANNED-21H05276, KAKENHI-PROJECT-20H00448, KAKENHI-PROJECT-20H03438, KAKENHI-PROJECT-20K06493, KAKENHI-PROJECT-21K19413
[Journal Article] Tissue-specific expression of the SARS-CoV-2 receptor, angiotensin-converting enzyme 2, in mouse models of chronic kidney disease2021
- Author(s)
  Tsukamoto Shunichiro、Wakui Hiromichi、Azushima Kengo、Yamaji Takahiro、Urate Shingo、Suzuki Toru、Abe Eriko、Tanaka Shohei、Taguchi Shinya、Yamada Takayuki、Kinguchi Sho、Kamimura Daisuke、Yamashita Akio、Sano Daisuke、Nakano Masayuki、Hashimoto Tatsuo、Tamura Kouichi
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 16843-16843
- DOI
  10.1038/s41598-021-96294-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22601, KAKENHI-PROJECT-20H03438, KAKENHI-PROJECT-20K07786, KAKENHI-PROJECT-21K19413
[Journal Article] Effects of tumor necrosis factor-α inhibition on kidney fibrosis and inflammation in a mouse model of aristolochic acid nephropathy2021
- Author(s)
  Taguchi Shinya、Azushima Kengo、Yamaji Takahiro、Urate Shingo、Suzuki Toru、Abe Eriko、Tanaka Shohei、Tsukamoto Shunichiro、Kamimura Daisuke、Kinguchi Sho、Yamashita Akio、Wakui Hiromichi、Tamura Kouichi
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 23587-23587
- DOI
  10.1038/s41598-021-02864-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22601, KAKENHI-PROJECT-20K22908, KAKENHI-PROJECT-18H02735, KAKENHI-PROJECT-20H03438, KAKENHI-PROJECT-20K07786, KAKENHI-PROJECT-20K21606, KAKENHI-PROJECT-21K19413, KAKENHI-PROJECT-21K16166
[Journal Article] Aristolochic Acid Induces Renal Fibrosis and Senescence in Mice2021
- Author(s)
  Urate Shingo、Wakui Hiromichi、Azushima Kengo、Yamaji Takahiro、Suzuki Toru、Abe Eriko、Tanaka Shohei、Taguchi Shinya、Tsukamoto Shunichiro、Kinguchi Sho、Uneda Kazushi、Kanaoka Tomohiko、Atobe Yoshitoshi、Funakoshi Kengo、Yamashita Akio、Tamura Kouichi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 22 Pages: 12432-12432
- DOI
  10.3390/ijms222212432
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08730, KAKENHI-PROJECT-19K17575, KAKENHI-PROJECT-20K07786, KAKENHI-PROJECT-21K19413
[Journal Article] De novo ATP1A3 variants cause polymicrogyria2021
- Author(s)
  Miyatake Satoko、Kato Mitsuhiro、Kumamoto Takuma、Hirose Tomonori、他
- Journal Title
  
  Science Advances
  
  Volume: 7 Issue: 13 Pages: 2368-2368
- DOI
  10.1126/sciadv.abd2368
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K06893, KAKENHI-PROJECT-20K07907, KAKENHI-PROJECT-20K08164, KAKENHI-PROJECT-19K22601, KAKENHI-PROJECT-18K15677, KAKENHI-PUBLICLY-19H04795, KAKENHI-PLANNED-20H05777, KAKENHI-PROJECT-20H03641, KAKENHI-PROJECT-18K19305, KAKENHI-PROJECT-19K16921, KAKENHI-PROJECT-19K08281, KAKENHI-PROJECT-20H03438, KAKENHI-ORGANIZER-21H05158, KAKENHI-PLANNED-21H05159, KAKENHI-PROJECT-19H03228, KAKENHI-PROJECT-20H03270, KAKENHI-PROJECT-21H02405, KAKENHI-PROJECT-20K08236, KAKENHI-PROJECT-21K06051, KAKENHI-PROJECT-21K19356, KAKENHI-PROJECT-21K19413
[Journal Article] New vaccine production platforms used in developing SARS-CoV-2 vaccine candidates2021
- Author(s)
  Ura Takehiro、Yamashita Akio、Mizuki Nobuhisa、Okuda Kenji、Shimada Masaru
- Journal Title
  
  Vaccine
  
  Volume: 39 Issue: 2 Pages: 197-201
- DOI
  10.1016/j.vaccine.2020.11.054
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09603, KAKENHI-PROJECT-19K22601, KAKENHI-PROJECT-20H03438
[Journal Article] Potent mouse monoclonal antibodies that block SARS-CoV-2 infection2021
- Author(s)
  Guo Youjia、Kawaguchi Atsushi、Takeshita Masaru、Sekiya Takeshi、Hirohama Mikako、Yamashita Akio、Siomi Haruhiko、Murano Kensaku
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 296 Pages: 100346-100346
- DOI
  10.1016/j.jbc.2021.100346
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22601, KAKENHI-PROJECT-20K21507, KAKENHI-PLANNED-19H05753, KAKENHI-PROJECT-20H03439, KAKENHI-PROJECT-18K07137, KAKENHI-PROJECT-20H03438, KAKENHI-PROJECT-19H03475, KAKENHI-PROJECT-21K07036
[Journal Article] Shank2 Binds to aPKC and Controls Tight Junction Formation with Rap1 Signaling during Establishment of Epithelial Cell Polarity2020
- Author(s)
  Sasaki Kazunori、Kojitani Noriko、Hirose Hiroko、Yoshihama Yohei、Suzuki Hidefumi、Shimada Miho、Takayanagi Ayumi、Yamashita Akio、Nakaya Masa-aki、Hirano Hisashi、Takahashi Hidehisa、Ohno Shigeo
- Journal Title
  
  Cell Reports
  
  Volume: 31 Issue: 1 Pages: 107407-107407
- DOI
  10.1016/j.celrep.2020.02.088
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06482, KAKENHI-PROJECT-19K22601, KAKENHI-PROJECT-20K15718, KAKENHI-PROJECT-18H02378, KAKENHI-PROJECT-19K22401, KAKENHI-PROJECT-20H03438
[Journal Article] The human papillomavirus E6 protein targets apoptosis-inducing factor (AIF) for degradation2020
- Author(s)
  Shimada M, Yamashita A, Saito M, Ichino M, Kinjo T, Mizuki N, Klinman DM, Okuda K
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 1-14
- DOI
  10.1038/s41598-020-71134-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08655, KAKENHI-PROJECT-20K09603, KAKENHI-PROJECT-19K22601, KAKENHI-PROJECT-20H03438
[Journal Article] Effects of Rikkunshito treatment on renal fibrosis/inflammation and body weight reduction in a unilateral ureteral obstruction model in mice2020
- Author(s)
  Wakui H, Yamaji T, Azushima K, Uneda K, Haruhara K, Nakamura A, Ohki K, Kinguchi S, Kobayashi R, Urate S, Suzuki T, Kamimura D, Minegishi S, Ishigami T, Kanaoka T, Matsuo K, Miyazaki T, Fujikawa T, Yamashita A, Tamura K.
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 1782-1782
- DOI
  10.1038/s41598-020-58214-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22601, KAKENHI-PROJECT-19K17575, KAKENHI-PROJECT-17K09313, KAKENHI-PROJECT-19K21318, KAKENHI-PROJECT-19K08730, KAKENHI-PROJECT-20K07786
[Journal Article] Effects of ATRAP in Renal Proximal Tubules on Angiotensin‐Dependent Hypertension2019
- Author(s)
  Kinguchi Sho、Wakui Hiromichi、Azushima Kengo、Haruhara Kotaro、Koguchi Tomoyuki、Ohki Kohji、Uneda Kazushi、Matsuda Miyuki、Haku Sona、Yamaji Takahiro、Yamada Takayuki、Kobayashi Ryu、Minegishi Shintaro、Ishigami Tomoaki、Yamashita Akio、Fujikawa Tetsuya、Tamura Kouichi
- Journal Title
  
  Journal of the American Heart Association
  
  Volume: 8 Issue: 8
- DOI
  10.1161/jaha.119.012395
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05671, KAKENHI-PROJECT-17H06993, KAKENHI-PROJECT-17K19665, KAKENHI-PROJECT-17K16091, KAKENHI-PROJECT-19K22601, KAKENHI-PROJECT-19K17575, KAKENHI-PROJECT-19K18010, KAKENHI-PROJECT-18H02735, KAKENHI-PROJECT-17K09313, KAKENHI-PROJECT-19K21318
[Journal Article] Translation-dependent unwinding of stem?loops by UPF1 licenses Regnase-1 to degrade inflammatory mRNAs2019
- Author(s)
  Mino Takashi、Iwai Noriki、Endo Masayuki、Inoue Kentaro、Akaki Kotaro、Hia Fabian、Uehata Takuya、Emura Tomoko、Hidaka Kumi、Suzuki Yutaka、Standley Daron M、Okada-Hatakeyama Mariko、Ohno Shigeo、Sugiyama Hiroshi、Yamashita Akio、Takeuchi Osamu
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 47 Pages: 8838-8859
- DOI
  10.1093/nar/gkz628
- NAID
  120006708220
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22601, KAKENHI-PROJECT-18KK0139, KAKENHI-PROJECT-18H05278, KAKENHI-PROJECT-18H02430, KAKENHI-PROJECT-19H03488, KAKENHI-PROJECT-16H06279, KAKENHI-PROJECT-16H06356, KAKENHI-PROJECT-18K15185
[Journal Article] N4BP1 restricts HIV-1 and its inactivation by MALT1 promotes viral reactivation.2019
- Author(s)
  Yamasoba D, Sato K, Ichinose T, Imamura T, Koepke L, Joas S, Reith E, Hotter D, Misawa N, Akaki K, Uehata T, Mino T, Miyamoto S, Noda T, Yamashita A, Standley DM, Kirchhoff F, Sauter D, Koyanagi Y, Takeuchi O.
- Journal Title
  
  Nat Microbiol
  
  Volume: 4 Issue: 9 Pages: 1532-1544
- DOI
  10.1038/s41564-019-0460-3
- NAID
  120006731123
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22529, KAKENHI-PROJECT-19K22601, KAKENHI-PROJECT-18KK0447, KAKENHI-INTERNATIONAL-16K21723, KAKENHI-ORGANIZER-16H06429, KAKENHI-PROJECT-18H05278, KAKENHI-PROJECT-17H04082, KAKENHI-PROJECT-18H02430, KAKENHI-PROJECT-18H02662, KAKENHI-PROJECT-19H03488, KAKENHI-PROJECT-17J10132, KAKENHI-PROJECT-18K15185
[Journal Article] Angiotensin II type 1 receptor-associated protein deficiency attenuates sirtuin1 expression in an immortalised human renal proximal tubule cell line2019
- Author(s)
  Yamaji T, Yamashita A, Wakui H, Azushima K, Uneda K, Fujikawa Y, Haku S, Kobayashi R, Ohki K, Haruhara K, Kinguchi S, Ishii T, Yamada T, Urate S, Suzuki T, Abe E, Tanaka S, Kamimura D, Ishigami T, Toya Y, Takahashi H, Tamura K.
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 16550-16550
- DOI
  10.1038/s41598-019-52566-y
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22601, KAKENHI-PROJECT-19K17575, KAKENHI-PROJECT-19K18010, KAKENHI-PROJECT-18H02735, KAKENHI-PROJECT-17K09313, KAKENHI-PROJECT-19K21318
[Journal Article] Environmental stresses suppress nonsense-mediated mRNA decay (NMD) and affect cells by stabilizing NMD-targeted gene expression2019
- Author(s)
  Usuki Fusako、Yamashita Akio、Fujimura Masatake
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 1279-1279
- DOI
  10.1038/s41598-018-38015-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-17H05671, KAKENHI-PROJECT-17K19665
[Journal Article] Effects of rikkunshito on renal fibrosis and inflammation in angiotensin II-infused mice2019
- Author(s)
  Azushima Kengo、Uneda Kazushi、Wakui Hiromichi、Ohki Kohji、Haruhara Kotaro、Kobayashi Ryu、Haku Sona、Kinguchi Sho、Yamaji Takahiro、Minegishi Shintaro、Ishigami Tomoaki、Yamashita Akio、Tamura Kouichi
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 6201-6201
- DOI
  10.1038/s41598-019-42657-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05671, KAKENHI-PROJECT-17H06993, KAKENHI-PROJECT-17K19665, KAKENHI-PROJECT-19K22601, KAKENHI-PROJECT-19K17575, KAKENHI-PROJECT-18H02735, KAKENHI-PROJECT-17K09313, KAKENHI-PROJECT-19K21318
[Journal Article] Early Enhanced Leucine-Rich α-2-Glycoprotein-1 Expression in Glomerular Endothelial Cells of Type 2 Diabetic Nephropathy Model Mice2018
- Author(s)
  haku Sona、Wakui Hiromichi、Azushima Kengo、Haruhara Kotaro、Kinguchi Sho、Ohki Kohji、Uneda Kazushi、Kobayashi Ryu、Matsuda Miyuki、Yamaji Takahiro、Yamada Takayuki、Minegishi Shintaro、Ishigami Tomoaki、Yamashita Akio、Ohashi Kenichi、Tamura Kouichi
- Journal Title
  
  BioMed Research International
  
  Volume: 2018 Pages: 1-9
- DOI
  10.1155/2018/2817045
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09313, KAKENHI-PUBLICLY-17H05671, KAKENHI-PROJECT-18H02735, KAKENHI-PROJECT-17K19665, KAKENHI-PROJECT-17K09730
[Journal Article] Angiotensin receptor-binding molecule in leukocytes in association with the systemic and leukocyte inflammatory profile2018
- Author(s)
  Haruhara Kotaro、Wakui Hiromichi、Azushima Kengo、Kurotaki Daisuke、Kawase Wataru、Uneda Kazushi、Haku Sona、Kobayashi Ryu、Ohki Kohji、Kinguchi Sho、Ohsawa Masato、Minegishi Shintaro、Ishigami Tomoaki、Matsuda Miyuki、Yamashita Akio、Nakajima Hideaki、Tamura Tomohiko、Tsuboi Nobuo、Yokoo Takashi、Tamura Kouichi
- Journal Title
  
  Atherosclerosis
  
  Volume: 269 Pages: 236-244
- DOI
  10.1016/j.atherosclerosis.2018.01.013
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19665, KAKENHI-PUBLICLY-17H05671, KAKENHI-PROJECT-15H04331, KAKENHI-PROJECT-17H06993, KAKENHI-PROJECT-17K09313, KAKENHI-PROJECT-18H02735, KAKENHI-PROJECT-16K09647, KAKENHI-PROJECT-17K09730
[Journal Article] Angiotensin II Type 1 Receptor-associated Protein Inhibits Angiotensin II-induced Insulin Resistance with Suppression of Oxidative Stress in Skeletal Muscle Tissue2018
- Author(s)
  Ohki Kohji、Wakui Hiromichi、Kishio Nozomu、Azushima Kengo、Uneda Kazushi、Haku Sona、Kobayashi Ryu、Haruhara Kotaro、Kinguchi Sho、Yamaji Takahiro、Yamada Takayuki、Minegishi Shintaro、Ishigami Tomoaki、Toya Yoshiyuki、Yamashita Akio、Imajo Kento、Nakajima Atsushi、Kato Ikuma、Ohashi Kenichi、Tamura Kouichi
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 2846-2846
- DOI
  10.1038/s41598-018-21270-8
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19665, KAKENHI-PUBLICLY-17H05671, KAKENHI-PROJECT-15H04331, KAKENHI-PROJECT-17H06993, KAKENHI-PROJECT-16K19558, KAKENHI-PROJECT-17K09313, KAKENHI-PROJECT-18H02735, KAKENHI-PROJECT-19K21318
[Journal Article] Endoplasmic reticulum stress preconditioning modifies intracellular mercury content by upregulating membrane transporters2017
- Author(s)
  Usuki Fusako、Fujimura Masatake、Yamashita Akio
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 12390-12390
- DOI
  10.1038/s41598-017-09435-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19665, KAKENHI-PUBLICLY-17H05671, KAKENHI-PROJECT-15H04331
[Journal Article] Translational control of mRNAs by 3'-Untranslated region binding proteins2017
- Author(s)
  Yamashita Akio、Takeuchi Osamu
- Journal Title
  
  BMB Reports
  
  Volume: 50 Issue: 4 Pages: 194-200
- DOI
  10.5483/bmbrep.2017.50.4.040
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19665, KAKENHI-PUBLICLY-17H05671
[Journal Article] ATRAP Expression in Brown Adipose Tissue Does Not Influence the Development of Diet-Induced Metabolic Disorders in Mice2017
- Author(s)
  Wakui H, Ohki K, Azushima K, Uneda K, Haku S, Kobayashi R, Haruhara K, Kinguchi S, Matsuda M, Ohsawa M, Maeda A, Minegishi S, Ishigami T, Toya Y, Yamashita A, Umemura S, Tamura K
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 18 Issue: 3 Pages: 676-676
- DOI
  10.3390/ijms18030676
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19536, KAKENHI-PROJECT-16K09647, KAKENHI-PROJECT-17K09313, KAKENHI-PROJECT-17K19665, KAKENHI-PUBLICLY-17H05671, KAKENHI-PROJECT-15H04331, KAKENHI-PROJECT-15K09293, KAKENHI-PROJECT-16K19558
[Journal Article] Translational control of mRNAs by 3'-Untranslated region binding proteins.2017
- Author(s)
  Yamashita A, Takeuchi O.
- Journal Title
  
  BMB Reports
  
  Volume: 50 Pages: 194-200
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04331
[Journal Article] Angiotensin II Type 1 Receptor‐Associated Protein Regulates Kidney Aging and Lifespan Independent of Angiotensin2017
- Author(s)
  Uneda Kazushi、Wakui Hiromichi、Maeda Akinobu、Azushima Kengo、Kobayashi Ryu、Haku Sona、Ohki Kohji、Haruhara Kotaro、Kinguchi Sho、Matsuda Miyuki、Ohsawa Masato、Minegishi Shintaro、Ishigami Tomoaki、Toya Yoshiyuki、Atobe Yoshitoshi、Yamashita Akio、Umemura Satoshi、Tamura Kouichi
- Journal Title
  
  Journal of the American Heart Association
  
  Volume: 6 Issue: 8
- DOI
  10.1161/jaha.117.006120
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09647, KAKENHI-PROJECT-17K09313, KAKENHI-PROJECT-17K19665, KAKENHI-PUBLICLY-17H05671, KAKENHI-PROJECT-15H04331, KAKENHI-PROJECT-17H06993, KAKENHI-PROJECT-15K09293
[Journal Article] Adipocyte-Specific Enhancement of Angiotensin II Type 1 Receptor-Associated Protein Ameliorates Diet-Induced Visceral Obesity and Insulin Resistance.2017
- Author(s)
  Azushima K, Ohki K, Wakui H, Uneda K, Haku S, Kobayashi R, Haruhara K, Kinguchi S, Matsuda M, Maeda A, Toya Y, Yamashita A, Umemura S, Tamura K.
- Journal Title
  
  J Am Heart Assoc.
  
  Volume: 6 Issue: 3
- DOI
  10.1161/jaha.116.004488
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04331, KAKENHI-PROJECT-15K19536, KAKENHI-PROJECT-16K19558, KAKENHI-PROJECT-17K09313, KAKENHI-PROJECT-17K19665, KAKENHI-PUBLICLY-17H05671, KAKENHI-PROJECT-15K09293
[Journal Article] SMG12017
- Author(s)
  Yamashita A
- Journal Title
  
  Encyclopedia of Signaling Molecules 2nd edition
  
  Volume: 印刷中
- Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H04331
[Journal Article] An angiotensin II type 1 receptor binding molecule has a critical role in hypertension in a chronic kidney disease model.2017
- Author(s)
  Kobayashi R, Wakui H, Azushima K, Uneda K, Haku S, Ohki K, Haruhara K, Kinguchi S, Matsuda M, Ohsawa M, Toya Y, Nishiyama A, Yamashita A, Tanabe K, Maeshima Y, Umemura S, Tamura K.
- Journal Title
  
  Kidney Int.
  
  Volume: 91 Issue: 5 Pages: 1115-1125
- DOI
  10.1016/j.kint.2016.10.035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04331, KAKENHI-PROJECT-15K19536, KAKENHI-PROJECT-17K09313, KAKENHI-PROJECT-17K19665, KAKENHI-PUBLICLY-17H05671, KAKENHI-PROJECT-15K09293
[Journal Article] The RNA helicase DHX34 functions as a scaffold for SMG1-mediated UPF1 phosphorylation.2016
- Author(s)
  Melero R, Hug N, López-Perrote A, Yamashita A, Cáceres JF, Llorca O.
- Journal Title
  
  Nat Commun.
  
  Volume: 7 Issue: 1 Pages: 10585-10585
- DOI
  10.1038/ncomms10585
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04331
[Journal Article] HEK293T細胞を用いたリコンビナントタンパク質精製．2016
- Author(s)
  山下暁朗
- Journal Title
  
  実験医学
  
  Volume: 34 Pages: 3057-3064
- Data Source
  KAKENHI-PROJECT-15H04331
[Journal Article] Human nonsense-mediated mRNA decay factor UPF2 interacts directly with eRF3 and the SURF complex.2016
- Author(s)
  López-Perrote A, Castaño R, Melero R, Zamarro T, Kurosawa H, Ohnishi T, Uchiyama A, Aoyagi K, Buchwald G, Kataoka N, Yamashita A, Llorca O.
- Journal Title
  
  Nucleic Acids Res.
  
  Volume: 44 Issue: 4 Pages: 1909-1923
- DOI
  10.1093/nar/gkv1527
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04331
[Journal Article] 11.mRNA 3'UTR結合タンパク質による翻訳制御2015
- Author(s)
  山下暁朗，竹内理
- Journal Title
  
  細胞工学
  
  Volume: 8 Pages: 762-765
- Data Source
  KAKENHI-PROJECT-15H04331
[Journal Article] Mutations in the glutaminyl-tRNA synthetase gene cause early-onset epileptic encephalopathy.2015
- Author(s)
  Kodera H, Osaka H, Iai M, Aida N, Yamashita A, Tsurusaki Y, Nakashima M, Miyake N, Saitsu H, Matsumoto N.
- Journal Title
  
  J Hum Genet.
  
  Volume: 60(2) Issue: 2 Pages: 97-101
- DOI
  10.1038/jhg.2014.103
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-21115004, KAKENHI-PROJECT-23591264, KAKENHI-PROJECT-25293235, KAKENHI-PROJECT-25860915, KAKENHI-PROJECT-26860816, KAKENHI-ORGANIZER-24118001, KAKENHI-PLANNED-24118007
[Journal Article] miRNAによる標的制御2015
- Author(s)
  山下暁朗
- Journal Title
  
  実験医学
  
  Volume: 20 Pages: 3244-3255
- Data Source
  KAKENHI-PROJECT-15H04331
[Journal Article] Renal Tubule Angiotensin II Type 1 Receptor-Associated Protein Promotes Natriuresis and Inhibits Salt-Sensitive Blood Pressure Elevation.2015
- Author(s)
  Wakui H, Uneda K, Tamura K, Ohsawa M, Azushima K, Kobayashi R, Ohki K, Dejima T, Kanaoka T, Tsurumi-Ikeya Y, Matsuda M, Haruhara K, Nishiyama A, Yabana M, Fujikawa T, Yamashita A, Umemura S.
- Journal Title
  
  J Am Heart Assoc.
  
  Volume: 19;4(3) Issue: 3 Pages: 1-14
- DOI
  10.1161/jaha.114.001594
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-21115004, KAKENHI-PROJECT-15K09293, KAKENHI-PROJECT-15H04331, KAKENHI-PROJECT-26893218, KAKENHI-PROJECT-25460906
[Journal Article] aPKCλ maintains the integrity of the glomerular slit diaphragm through trafficking of nephrin to the cell surface.2014
- Author(s)
  Satoh D, Hirose T, Harita Y, Daimon C, Harada T, Kurihara H, Yamashita A, Ohno S.
- Journal Title
  
  J Biochem.
  
  Volume: 156(2) Issue: 2 Pages: 115-28
- DOI
  10.1093/jb/mvu022
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-21115004, KAKENHI-PROJECT-23687025, KAKENHI-PROJECT-24390259, KAKENHI-PROJECT-24591214, KAKENHI-PROJECT-25461617, KAKENHI-PLANNED-23112003
[Journal Article] A hemizygous GYG2 mutation and Leigh syndrome: a possible link?2014
- Author(s)
  Imagawa E, Osaka H, Yamashita A, Shiina M, Takahashi E, Sugie H, Nakashima M, Tsurusaki Y, Saitsu H, Ogata K, Matsumoto N, Miyake N.
- Journal Title
  
  Hum Genet.
  
  Volume: 133(2 Issue: 2 Pages: 225-34
- DOI
  10.1007/s00439-013-1372-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-21115004, KAKENHI-PROJECT-23687025, KAKENHI-ORGANIZER-24118001, KAKENHI-PLANNED-24118005, KAKENHI-PLANNED-24118007, KAKENHI-PROJECT-24249019, KAKENHI-PROJECT-25293235, KAKENHI-PROJECT-25461652, KAKENHI-PROJECT-25860915, KAKENHI-PROJECT-26330331
[Journal Article] A novel phosphorylation-independent interaction between SMG6 and UPF1 is essential for human NMD.2014
- Author(s)
  Nicholson P, Josi C, Kurosawa H, Yamashita A, Mühlemann O.
- Journal Title
  
  Nucleic Acids Res.
  
  Volume: 42(14) Issue: 14 Pages: 9217-35
- DOI
  10.1093/nar/gku645
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-21115004, KAKENHI-PROJECT-23687025
[Journal Article] Structures of SMG1-UPFs complexes: SMG1 contributes to regulate UPF2-dependent activation of UPF1 in NMD.2014
- Author(s)
  Melero R, Uchiyama A, Castaño R, Kataoka N, Kurosawa H, Ohno S, Yamashita A, Llorca O.
- Journal Title
  
  Structure.
  
  Volume: 22(8) Issue: 8 Pages: 1105-19
- DOI
  10.1016/j.str.2014.05.015
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-21115004, KAKENHI-PROJECT-23687025
[Journal Article] Effects of the Angiotensin receptor blocker olmesartan on adipocyte hypertrophy and function in mice with metabolic disorders.2014
- Author(s)
  Maeda A, Tamura K, Wakui H, Ohsawa M, Azushima K, Uneda K, Kanaoka T, Kobayashi R, Ohki K, Matsuda M, Tsurumi-Ikeya Y, Yamashita A, Tokita Y, Umemura S.
- Journal Title
  
  Biomed Res Int.
  
  Volume: 2014 Pages: 946492-946492
- DOI
  10.1155/2014/946492
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-21115004, KAKENHI-PROJECT-24591233, KAKENHI-PROJECT-24890189, KAKENHI-PROJECT-25460906
[Journal Article] Effects of Ang II receptor blocker irbesartan on adipose tissue function in mice with metabolic disorders.2014
- Author(s)
  Maeda A, Tamura K, Wakui H, Ohsawa M, Azushima K, Uneda K, Kobayashi R, Tsurumi-Ikeya Y, Kanaoka T, Dejima T, Ohki K, Haku S, Yamashita A, Umemura S.
- Journal Title
  
  Int J Med Sci.
  
  Volume: 11(6) Issue: 6 Pages: 646-51
- DOI
  10.7150/ijms.8577
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-21115004, KAKENHI-PROJECT-24591233, KAKENHI-PROJECT-24790950, KAKENHI-PROJECT-25460906
[Journal Article] Nonsense-mediated mRNA decay - Mechanisms of substrate mRNA recognition and degradation in mammalian cells.2013
- Author(s)
  Schweingruber, C.
- Journal Title
  
  Biochim Biophys Acta.
  
  Volume: Epub ahead of print Issue: 6-7 Pages: 1-11
- DOI
  10.1016/j.bbagrm.2013.02.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23687025, KAKENHI-PUBLICLY-23112718, KAKENHI-PLANNED-21115004
[Journal Article] The physiology and pathophysiology of a novel angiotensin receptor-binding protein ATRAP/Agtrap.2013
- Author(s)
  Tamura K, Wakui H, Maeda A, Dejima T, Ohsawa M, Azushima K, Kanaoka T, Haku S, Uneda K, Masuda S, Azuma K, Shigenaga A, Koide Y, Tsurumi-Ikeya Y, Matsuda M, Toya Y, Tokita Y, Yamashita A, Umemura S.
- Journal Title
  
  Curr Pharm Des.
  
  Volume: 19(17) Pages: 3043-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-21115004
[Journal Article] Enhanced angiotensin receptor-associated protein in renal tubule suppresses angiotensin-dependent hypertension.2013
- Author(s)
  Wakui H, Tamura K, Masuda S, Tsurumi-Ikeya Y, Fujita M, Maeda A, Ohsawa M, Azushima K, Uneda K, Matsuda M, Kitamura K, Uchida S, Toya Y, Kobori H, Nagahama K, Yamashita A, Umemura S.
- Journal Title
  
  Hypertension.
  
  Volume: 61(6) Issue: 6 Pages: 1203-10
- DOI
  10.1161/hypertensionaha.111.00572
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-21115004, KAKENHI-PROJECT-24591206, KAKENHI-PROJECT-24591233, KAKENHI-PROJECT-24790852, KAKENHI-PROJECT-24790950, KAKENHI-PROJECT-24890189
[Journal Article] An epigenetic switch is crucial for spermatogonia to exit the undifferentiated state toward a Kit-positive identity2013
- Author(s)
  Shirakawa, T., Yaman-Deveci, R., Tomizawa, S., Kamizato, Y., Nakajima, K., Sone, H., Sato, Y., Sharif, J., Yamashita, A., Takada-Horisawa, Y., Yoshida, S., Ura, K., Muto, M., Koseki, H., Suda, T., and Ohbo, K.
- Journal Title
  
  Development
  
  Volume: 140 Issue: 17 Pages: 3565-3576
- DOI
  10.1242/dev.094045
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-11J09354, KAKENHI-PLANNED-20116004, KAKENHI-PLANNED-21115004, KAKENHI-PLANNED-22131003, KAKENHI-PROJECT-23249015, KAKENHI-PROJECT-23687025, KAKENHI-PROJECT-24247041, KAKENHI-PLANNED-25114004, KAKENHI-PROJECT-25670097
[Journal Article] Bofu-tsu-shosan, an oriental herbal medicine, exerts a combinatorial favorable metabolic modulation including antihypertensive effect on a mouse model of human metabolic disorders with visceral obesity.2013
- Author(s)
  Azushima K, Tamura K, Wakui H, Maeda A, Ohsawa M, Uneda K, Kobayashi R, Kanaoka T, Dejima T, Fujikawa T, Yamashita A, Toya Y, Umemura S.
- Journal Title
  
  PLoS One.
  
  Volume: 8(10) Issue: 10 Pages: e75560-e75560
- DOI
  10.1371/journal.pone.0075560
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-21115004, KAKENHI-PROJECT-23687025, KAKENHI-PROJECT-24591233, KAKENHI-PROJECT-24790950, KAKENHI-PROJECT-25460906
[Journal Article] Role of SMG-1-mediated Upf1 phosphorylation in mammalian nonsense-mediated mRNA decay.2013
- Author(s)
  Yamashita A.
- Journal Title
  
  Genes Cells.
  
  Volume: 18(3) Issue: 3 Pages: 161-75
- DOI
  10.1111/gtc.12033
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-21115004, KAKENHI-PROJECT-23687025, KAKENHI-PUBLICLY-23112718
[Journal Article] Activation of angiotensin II type 1 receptor-associated protein exerts an inhibitory effect on vascular hypertrophy and oxidative stress in angiotensin II-mediated hypertension.2013
- Author(s)
  Wakui H, Dejima T, Tamura K, Uneda K, Azuma K, Maeda A, Ohsawa M, Kanaoka T, Azushima K, Kobayashi R, Matsuda M, Yamashita A, Umemura S.
- Journal Title
  
  Cardiovasc Res.
  
  Volume: 100(3) Issue: 3 Pages: 511-9
- DOI
  10.1093/cvr/cvt225
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-21115004, KAKENHI-PROJECT-23687025, KAKENHI-PROJECT-24591233, KAKENHI-PROJECT-24790950
[Journal Article] Endoplasmic reticulum stress preconditioning attenuates methylmercury-induced cellular damage by inducing favorable stress responses.2013
- Author(s)
  Usuki F, Fujimura M, Yamashita A
- Journal Title
  
  Sci Rep
  
  Volume: 3 Issue: 1 Pages: 2346-2346
- DOI
  10.1038/srep02346
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23687025, KAKENHI-PROJECT-25460402
[Journal Article] The novel PAR-1-binding protein MTCL1 has crucial roles in organizing microtubules in polarizing epithelial cells.2013
- Author(s)
  Sato Y, Akitsu M, Amano Y, Yamashita K, Ide M, Shimada K, Yamashita A, Hirano H, Arakawa N, Maki T, Hayashi I, Ohno S, Suzuki A.
- Journal Title
  
  J Cell Sci.
  
  Volume: 126(Pt 20) Pages: 4671-83
- DOI
  10.1242/jcs.127845
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-21115004, KAKENHI-PLANNED-21116004, KAKENHI-PLANNED-23112003, KAKENHI-PROJECT-23687025, KAKENHI-PROJECT-25460695
[Journal Article] Inhibition of SMG-8, a subunit of SMG-1 kinase, ameliorates nonsense-mediated mRNA decay-exacerbated mutant phenotypes without cytotoxicity.2013
- Author(s)
  Usuki F, Yamashita A, Shiraishi T, Shiga A, Onodera O, Higuchi I, Ohno S
- Journal Title
  
  Proc Natl Acad Sci U S A
  
  Volume: 110 Issue: 37 Pages: 15037-42
- DOI
  10.1073/pnas.1300654110
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-23112003, KAKENHI-PROJECT-23687025, KAKENHI-PROJECT-25460402
[Journal Article] Upstream stimulatory factors 1 and 2 mediate the transcription of angiotensin II binding and inhibitory protein.2013
- Author(s)
  Matsuda M, Tamura K, Wakui H, Maeda A, Ohsawa M, Kanaoka T, Azushima K, Uneda K, Haku S, Tsurumi-Ikeya Y, Toya Y, Maeshima Y, Yamashita A, Umemura S.
- Journal Title
  
  J Biol Chem.
  
  Volume: 288(26) Issue: 26 Pages: 19238-49
- DOI
  10.1074/jbc.m113.451054
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-21115004, KAKENHI-PROJECT-23591193, KAKENHI-PROJECT-24591233, KAKENHI-PROJECT-24790950, KAKENHI-PROJECT-24890189, KAKENHI-PROJECT-25460906
[Journal Article] Angiotensin receptor-binding protein ATRAP/Agtrap inhibits metabolic dysfunction with visceral obesity.2013
- Author(s)
  Maeda A, Tamura K, Wakui H, Dejima T, Ohsawa M, Azushima K, Kanaoka T, Uneda K, Matsuda M, Yamashita A, Miyazaki N, Yatsu K, Hirawa N, Toya Y, Umemura S.
- Journal Title
  
  J Am Heart Assoc.
  
  Volume: 2(4) Issue: 4
- DOI
  10.1161/jaha.113.000312
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-21115004, KAKENHI-PROJECT-23687025, KAKENHI-PROJECT-24790950, KAKENHI-PROJECT-25460906
[Journal Article] Deletion of the angiotensin II type 1 receptor-associated protein enhances renal sodium reabsorption and exacerbates angiotensin II-mediated hypertension.2013
- Author(s)
  Ohsawa M, Tamura K, Wakui H, Maeda A, Dejima T, Kanaoka T, Azushima K, Uneda K, Tsurumi-Ikeya Y, Kobayashi R, Matsuda M, Uchida S, Toya Y, Kobori H, Nishiyama A, Yamashita A, Ishikawa Y, Umemura S.
- Journal Title
  
  Kidney Int.
  
  Volume: 86(3) Issue: 3 Pages: 570-81
- DOI
  10.1038/ki.2014.95
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-21115004, KAKENHI-PLANNED-22136009, KAKENHI-PROJECT-24390200, KAKENHI-PROJECT-24591233, KAKENHI-PROJECT-24890189, KAKENHI-PROJECT-25460906, KAKENHI-PROJECT-25670131
[Journal Article] Heat shock protein 90 regulates phosphatidylinositol 3-kinase-related protein kinase family proteins together with the RUVBL1/2 and Tel2-containing co-factor complex2012
- Author(s)
  Izumi N, Yamashita A, Hirano H, Ohno S
- Journal Title
  
  Cancer Sci
  
  Volume: 103 Issue: 1 Pages: 50-57
- DOI
  10.1111/j.1349-7006.2011.02112.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J02706, KAKENHI-PLANNED-21115004, KAKENHI-PROJECT-22247030, KAKENHI-PLANNED-23112003, KAKENHI-PUBLICLY-23112718, KAKENHI-PROJECT-23687025
[Journal Article] N- and C-terminal Upf1 phosphorylations create binding platforms for SMG-6 and SMG-5:SMG-7 during NMD2012
- Author(s)
  Okada-Katsuhata Y, Yamashita A, Kutsuzawa K, Izumi N, Hirahara F, Ohno S
- Journal Title
  
  Nucleic Acids Res
  
  Volume: 40 Issue: 3 Pages: 1251-1266
- DOI
  10.1093/nar/gkr791
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J02706, KAKENHI-PLANNED-21115004, KAKENHI-PROJECT-22247030, KAKENHI-PLANNED-23112003, KAKENHI-PUBLICLY-23112718, KAKENHI-PROJECT-23687025
[Journal Article] Integrated regulation of PIKK-mediated stress responses by AAA+ proteins RUVBL1 and RUVBL22012
- Author(s)
  Izumi N, Yamashita A and Ohno S
- Journal Title
  
  Nucleus
  
  Volume: 3 Issue: 1 Pages: 29-43
- DOI
  10.4161/nucl.18926
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22247030, KAKENHI-PUBLICLY-23112718, KAKENHI-PROJECT-23687025
[Journal Article] Analysis of interferon-beta mRNA stability control after poly(I:C) stimulation using RNA metabolic labeling by ethynyluridine.2012
- Author(s)
  Abe K, Ishigami T, Shyu A. B, Ohno S, Umemura S, Yamashita A
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 428(1) Issue: 1 Pages: 44-49
- DOI
  10.1016/j.bbrc.2012.09.144
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22247030, KAKENHI-PROJECT-23591221, KAKENHI-PROJECT-23687025, KAKENHI-PUBLICLY-23112718, KAKENHI-PLANNED-21115004
[Journal Article] Integrated regulation of PIKK-mediated stress responses by AAA+ proteins RUVBL1 and RUVBL2.2012
- Author(s)
  Izumi N, Yamashita A, Ohno S
- Journal Title
  
  Nucleus
  
  Volume: 3(1) Pages: 29-43
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22247030
[Journal Article] The nonsense-mediated mRNA decay SMG-1 kinase is regulated by large-scale conformational changes controlled by SMG-8.2011
- Author(s)
  Arias-Palomo E, Yamashita A, Fernandez IS, Nunez-Ramirez R, Bamba Y, Izumi N, Ohno S, Llorca O.
- Journal Title
  
  Genes Dev.
  
  Volume: 25(2) Pages: 153-164
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22247030
[Journal Article] Nonsense-Mediated mRNA Decay SMG-1 kinase is regulated by large-scale conformational changes controlled by SMG-8.2011
- Author(s)
  Arias-Palomo E, Yamashita A (co-first author), Fernandez IS, Nunez-Ramirez R, Bamba Y, Izumi N, Ohno S, Llorca S
- Journal Title
  
  Genes and Development
  
  Volume: 25 Pages: 153-164
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790289
[Journal Article] Post-transcriptional defects of antioxidant selenoenzymes cause oxidative stress under methylmercury exposure.2011
- Author(s)
  Usuki F, Yamashita A, Fujimum M
- Journal Title
  
  J Biol Chem
  
  Volume: 286 Pages: 6641-6649
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591015
[Journal Article] Characterization of SMG-9, an essential component of the nonsense-mediated mRNA decay SMG1C complex.2011
- Author(s)
  Fernandez1 SI, Yamashita A (co-first author), Arias-Palomo E, Bamba Y, Bartolome RA, Canales MA, Teixido J, Ohno S, Llorca O
- Journal Title
  
  Nucleic acid research. 39(1)
  
  Pages: 347-358
- Data Source
  KAKENHI-PROJECT-21790289
[Journal Article] Mutations in POLR3A and POLR3B encoding RNA Polymerase III subunits cause an autosomal-recessive hypomyelinating leukoencephalopathy.2011
- Author(s)
  Saitsu H. et al.
- Journal Title
  
  Am J Hum Genet.
  
  Volume: 89 Issue: 5 Pages: 644-651
- DOI
  10.1016/j.ajhg.2011.10.003
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21115004, KAKENHI-PROJECT-21390103, KAKENHI-PROJECT-22689011, KAKENHI-PROJECT-22790823, KAKENHI-PUBLICLY-23112718, KAKENHI-PROJECT-23659531, KAKENHI-PROJECT-23687025, KAKENHI-PROJECT-23689052
[Journal Article] A novel role for hSMG-1 in stress granule formation.2011
- Author(s)
  Brown J A, Roberts T L, Richards R, Woods R, Birrell G, Lim YC, Ohno S, Yamashita A, Abraham RT, Gueven N, Lavin MF
- Journal Title
  
  Mol Cell Biol
  
  Volume: 31(22) Pages: 4417-4429
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22247030
[Journal Article] Methylmercury-induced relative selenium deficiency causese oxidative stress through its post-transcriptional effect.2011
- Author(s)
  Usuki F, Yamashita A, Fujimura M
- Journal Title
  
  Journal of biological chemistry
  
  Volume: 286 Pages: 6641-6649
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790289
[Journal Article] A novel role for hSMG-1 in stress granule formation.2011
- Author(s)
  Brown JA. et al.
- Journal Title
  
  Cancer Sci.
  
  Volume: 31 Issue: 22 Pages: 4417-4429
- DOI
  10.1128/mcb.05987-11
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21115004, KAKENHI-PUBLICLY-23112718, KAKENHI-PROJECT-23687025
[Journal Article] Methylmercury-induced relative selenium deficiency causese oxidative stress through its post-transcriptional effect.2011
- Author(s)
  Usuki F, Yamashita A, Fujimura M
- Journal Title
  
  J Biol Chem. 286(8)
  
  Pages: 6641-6649
- Data Source
  KAKENHI-PROJECT-21790289
[Journal Article] Posttranscriptional defects of antioxidant selenoenzymes cause oxidative stress under methylmercury exposure.2011
- Author(s)
  Usuki F, Yamashita A, Fujimura M
- Journal Title
  
  J Biol Chem 286
  
  Pages: 6641-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591015
[Journal Article] Nonsense-Mediated mRNA Decay SMG-1 kinase is regulated by large-scale conformational changes controlled by SMG-8.2011
- Author(s)
  Arias-Palomo E, Yamashita A (co-first author), Fernandez IS, Nunez-Ramirez R, Bamba Y, Izumi N, Ohno S, Llorca S
- Journal Title
  
  Genes and Development.Genes Dev. 25(2)
  
  Pages: 153-164
- Data Source
  KAKENHI-PROJECT-21790289
[Journal Article] Characterization of SMG-9, an essential component of the nonsense-mediated mRNA decay SMG1C complex.2011
- Author(s)
  Fernandezl SI, Yamashita A (co-first author), Arias-Palomo E, Bamba Y, Bartolome RA, Canales MA, Teixido J, Ohno S, Llorca O
- Journal Title
  
  Nucleic acid research
  
  Volume: 39 Pages: 347-358
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790289
[Journal Article] Characterization of SMG-9, an essential component of the nonsense-mediated mRNA decay. SMG1C complex.2011
- Author(s)
  Fernandez IS, Yamashita A, Arias-Palomo E, Bamba Y, Bartolome RA, Canales MA, Teixido J, Ohno S, Llorca O
- Journal Title
  
  Nucleic Acids Res.
  
  Volume: 39(1) Pages: 347-358
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22247030
[Journal Article] AAA+ family ATPases, RUVBL1 and RUVBL2, coordinate PIKK family and play critical roles in Nonsense-mediated mRNA decay.2010
- Author(s)
  Izumi N, Yamashita A (corresponding author), Iwamatsu A, Kurata R, Nakamura H, Saari B, Hirano H, Anderson P, Ohno S
- Journal Title
  
  Science signaling (Science姉妹誌). (3)
  
  Pages: 27-27
- Data Source
  KAKENHI-PROJECT-21790289
[Journal Article] NMDによる変異mRNA排除と疾患2010
- Author(s)
  臼杵扶佐子、山下暁朗
- Journal Title
  
  細胞工学 19
  
  Pages: 155-160
- Data Source
  KAKENHI-PROJECT-20591015
[Journal Article] AAA+ proteins RUVBL1 and RUVBL2 coordinate PIKK activity and function in nonsense-mediated mRNA decay.2010
- Author(s)
  Izumi N, Yamashita A (Corresponding Author), Iwamatsu A, Kurata R, Nakamura H, Saari B, Hirano H, Anderson P, Ohno S.
- Journal Title
  
  Science signaling 3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790289
[Journal Article] ASPP2 regulates epithelial cell polarity through the PAR complex.2010
- Author(s)
  Cong W, Hirose T, Harita Y, Yamashita A, Mizuno K, Hirano H, Ohno S
- Journal Title
  
  Curr.Biol.
  
  Volume: 20(15) Pages: 1408-1414
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22247030
[Journal Article] NMDと疾患2010
- Author(s)
  臼杵扶佐子, 山下暁朗
- Journal Title
  
  細胞工学 29
  
  Pages: 155-160
- Data Source
  KAKENHI-PROJECT-21790289
[Journal Article] ASPP2 regulates epithelial cell polarity through the PAR complex.2010
- Author(s)
  Cong W, Hirose T, Harita Y, Yamashita A, Mizuno K, Hirano H, Ohno S
- Journal Title
  
  Curr Biol. 20(15)
  
  Pages: 1408-1414
- Data Source
  KAKENHI-PROJECT-21790289
[Journal Article] Analysis of Nonsense-Mediated mRNA Decay by Monitoring mRNA Half-Lives in Mammalian Cells.2010
- Author(s)
  Yamashita A, Ohno S
- Journal Title
  
  Cold Spring Harbor Protocols
  
  Volume: (2)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22247030
[Journal Article] The 8th and 9th tandem spectrin-like repeats of utrophin cooperatively form a functional unit to interact with polarity-regulating kinase PAR-1b.2010
- Author(s)
  Yamashita K, Suzuki A, Satoh Y, Ide M, Amano Y, Masuda-Hirata M, Hayashi Y.K, Hamada K, Ogata K, Ohno S
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 391(1) Pages: 812-817
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22247030
[Journal Article] ASPP2 regulates epithelial cell polarity through the PAR complex.2010
- Author(s)
  Cong W, Hirose T, Harita Y, Yamashita A, Mizuno K, Hirano H, Ohno S
- Journal Title
  
  Current biology
  
  Volume: 20 Pages: 1408-1414
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790289
[Journal Article] Analysis of Nonsense-mediated mRNA decay by the monitoring of mRNA half lives in mammalian cells.2010
- Author(s)
  Yamashita A (corresponding author), Ohno S.
- Journal Title
  
  CSH protocol. (2)
  
  Pages: 5386-5386
- Data Source
  KAKENHI-PROJECT-21790289
[Journal Article] AAA+ proteins RUVBL1 and RUVBL2 coordinate PIKK activity and function in nonsense-mediated mRNA decay2010
- Author(s)
  Izumi N, Yamashita A, Iwamatsu A, Kurata R, Nakamura H, Saari B, HiranoH, Anderson P and Ohno S
- Journal Title
  
  Sci Signal
  
  Volume: 116 Issue: 116 Pages: 27-27
- DOI
  10.1126/scisignal.2000468
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22247030
[Journal Article] Nonsense-mediated mRNA decay(NMD)による変異mRNA排除と疾患2010
- Author(s)
  臼杵扶佐子、山下暁朗
- Journal Title
  
  細胞工学 29
  
  Pages: 155-160
- Data Source
  KAKENHI-PROJECT-20591015
[Journal Article] AAA+ proteins RUVBL1 and RUVBL2 coordinate PIKK family and function in nonsense-mediated mRNA decay.2010
- Author(s)
  Izumi N, Yamashita A, Iwamatsu A, Kurata R, Nakamura H, Saari B, Hirano H, Anderson P, Ohno S
- Journal Title
  
  Science Signaling
  
  Volume: 3(116)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22247030
[Journal Article] Analysis of Nonsense-mediated mRNA decay by the monitoring of mRNA half lives in mammalian cells.2010
- Author(s)
  Yamashita A (Corresponding Author), Ohno S
- Journal Title
  
  CSH protocol 2(pdb.prot)
  
  Pages: 5386-5386
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790289
[Journal Article] ASPP2 regulates epithelial cell polarity through the PAR complex2010
- Author(s)
  Cong W, Hirose T, Harita Y, Yamashita A, Mizuno K, Hirano H and Ohno S
- Journal Title
  
  Curr Biol
  
  Volume: 20 Pages: 1408-14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22247030
[Journal Article] SMG-8 and SMG-9, two novel subunits of the SMG-1 complex, regulate remodeling of the mRNA surveillance complex during nonsense-mediated mRNA decay.2009
- Author(s)
  Yamashita A (Corresponding Author), Izumi N, Kashima I, Ohnishi T, Saari B, Katsuhata Y, Muramatsu R, Morita T, Iwamatsu A, Kurata R, Hachiya T, Hirano H, Anderson P, Ohno S
- Journal Title
  
  Genes and development 23
  
  Pages: 1091-1105
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790289
[Journal Article] SMG-8 and SMG-9, two novel subunits of the SMG-1 complex, regulate remodeling ofthe mRNA surveillance complex during nonsense-mediated mRNA decay2009
- Author(s)
  Akio Yamashita, Natsuko Izumi, Isao Kashima, Tetsuo Ohnishi, Bonnie Saari, Yukiko Katsuhata, Reiko Muramatsu, Tomoko Morita, Akihiro Iwamatsu, Rie Kurata, Takahisa Hachiya, Hisashi Hirano, Philip Anderson. and Shigeo Ohno
- Journal Title
  
  Genes and development 23
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19770151
[Journal Article] mRNA品質管理システムと疾患2009
- Author(s)
  山下暁朗, 臼杵扶佐子
- Journal Title
  
  タンパク質核酸酵素 54
  
  Pages: 2219-2225
- Data Source
  KAKENHI-PROJECT-21790289
[Journal Article] NMDによるmRNA排除と疾患…難治性遺伝性疾患治療への試み.2009
- Author(s)
  山下暁朗、臼杵扶佐子
- Journal Title
  
  蛋白質・核酸・酵素増刊
  
  Pages: 2219-2225
- Data Source
  KAKENHI-PROJECT-20591015
[Journal Article] SMG-8 and SMG-9, two novel subunits of the SMG-1 complex, regulate remodeling of the mRNA surveillance complex during nonsense-mediated mRNA decay.2009
- Author(s)
  Yamashita A (corresponding author), Izumi N, Kashima I, Ohnishi T, Saari B, Katsuhata Y, Muramatsu R, Morita T, Iwamatsu A, Kurata R, Hachiya T, Hirano H, Anderson P, Ohno S.
- Journal Title
  
  Genes and Development. 23(9)
  
  Pages: 1091-1105
- Data Source
  KAKENHI-PROJECT-21790289
[Journal Article] SMG-8 and SMG-9, two novel subunits of the SMG-1 complex, regulate remodeling of the mRNA surveillance complex during nonsense-mediated mRNA decay.2009
- Author(s)
  Yamashita A, Izumi N, Kashima I, Ohnishi T, Saari B, Katsuhata Y, Muramatsu R, Morita T, Iwamatsu A, Kurata R, Hachiya T, Hirano H, Anderson P, Ohno S
- Journal Title
  
  Genes Dev 23(9)(in press)
- Data Source
  KAKENHI-PROJECT-19770151
[Journal Article] Versatile applications of transcriptional pulsing to study m RNA turnover in mammalian cells2007
- Author(s)
  Chen CY, Yamashita Y, Chang TC, Yamashita A, Zhu W, Zhong Z, Shyu AB
- Journal Title
  
  RNA 13
  
  Pages: 1775-1786
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19770151
[Journal Article] Distant N- and C-terminal domains are required for intrinsic kinase activity of SMG-1, a critical component of nonsense-mediated mRNA decay.2007
- Author(s)
  Morita T, Yamashita A, Kashima I, Ogata K, Ishiura S, Ohno S.
- Journal Title
  
  J Biol Chem. 16 ; 282(11)
  
  Pages: 7799-7808
- Data Source
  KAKENHI-PROJECT-19770151
[Journal Article] Distant N- and C-terminal domains are required for intrinsic kinase activity of SMG-1, a critical component of nonsense-mediated mRNA decay.2007
- Author(s)
  Morita T, Yamashita A, Kashima I, Ogata K, Ishiura S, Ohno S.
- Journal Title
  
  J Biol Chem 282(11)
  
  Pages: 7799-808
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590969
[Journal Article] Versatile applications of transcriptional pulsing to study mRNA turnover in mammalian cells2007
- Author(s)
  Chen CY, Yamashita Y, Chang TC, Yamashita A, Zhu W, Zhong Z, Shyu AB
- Journal Title
  
  RNA (10)
  
  Pages: 1775-1786
- Data Source
  KAKENHI-PROJECT-19770151
[Journal Article] Human TOB, an antiproliferative transcription factor, is a poly(A)-binding protein-dependent positive regulator of cytoplasmic mRNA deadenylation.2007
- Author(s)
  Ezzeddine N, Chang TC, Zhu W, Yamashita A, Chen CY, Zhong Z, Yamashita Y, Zheng D, Shyu AB
- Journal Title
  
  Mol. Cell. Biol. 27(22)
  
  Pages: 7791-7801
- Data Source
  KAKENHI-PROJECT-19770151
[Journal Article] Distant N- and C-terminal domains are required for intrinsic kinase activity of SMG-1, a critical component of nonsense-mediated mRNA decay.2007
- Author(s)
  Morita T, Yamashita A, Kashima I, Ogata K, Ishiura S, Ohno S
- Journal Title
  
  J Biol Chem 282
  
  Pages: 7799-8089
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590969
[Journal Article] Human TOB,an antiproliferative transcription factor,is apoly(A)-binding protein-dependent positive regulator of cyto plasmic mRNA deadenylation.2007
- Author(s)
  Ezzeddine N, Chang TC, Zhu W, Yamashita A, Chen CY, Zhong Z, Yamashita Y, Zheng D, Shyu AB
- Journal Title
  
  Mol.Cell.Biol 27
  
  Pages: 7791-7801
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19770151
[Journal Article] Distant N-andC-terminal domatns are required fbr intrinsic kinase activity of SMG-1,a critical component of nonsense-mediated mRNA decay2007
- Author(s)
  Morita T, Yamashita A, Kashima I, Ogata K, Ishiura S, Ohno S
- Journal Title
  
  J.Biol., Chem 282
  
  Pages: 7799-7808
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19770151
[Journal Article] Specific inhibition of nonsense-mediated mRNA decay components, SMG-1 or Upf1, rescues the phenotype of Ullrich's disease fibroblasts2006
- Author(s)
  Usuki F, Yamashita A, Kashima I, Higuchi I, Osame M, Ohno S
- Journal Title
  
  Molecular Therapy 14
  
  Pages: 351-60
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590969
[Journal Article] Specific inhibition of nonsense-mediated mRNA decay components, SMG-1 or Upfl, rescues the phenotype of Ullrich's disease fibroblasts2006
- Author(s)
  Usuki F, Yamashita A, Kashima I, Higuchi I, Osame M, Ohno S
- Journal Title
  
  Molecular Therapy 14
  
  Pages: 351-60
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590969
[Presentation] mRNA監視機構制御因子SMG1キナーゼによる酸化ストレス応答制御機構2021
- Author(s)
  山下暁朗
- Organizer
  第44回　日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K19413
[Presentation] mRNA監視機構制御因子SMG1キナーゼによる酸化ストレス応答制御機構2021
- Author(s)
  山下暁朗
- Organizer
  第44回　日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K22601
[Presentation] mRNA翻訳による生命現象制御の新展開2021
- Author(s)
  山下暁朗、藤原俊伸
- Organizer
  第44回　日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K19413
[Presentation] mRNA監視機構制御因子SMG1キナーゼによる酸化ストレス応答制御機構2021
- Author(s)
  山下暁朗
- Organizer
  第44回　日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20H03438
[Presentation] mRNA翻訳による生命現象制御の新展開2021
- Author(s)
  山下暁朗、藤原俊伸
- Organizer
  第44回　日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20H03438
[Presentation] mRNA翻訳による生命現象制御の新展開2021
- Author(s)
  山下暁朗、藤原俊伸
- Organizer
  第44回　日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K22601
[Presentation] mRNA監視機構制御因子SMG1キナーゼによる酸化ストレス応答制御機構2020
- Author(s)
  山下暁朗
- Organizer
  日本分子生物学会
- Data Source
  KAKENHI-PROJECT-19K22601
[Presentation] mRNA監視機構制御因子SMG1キナーゼによる酸化ストレス応答制御機構2020
- Author(s)
  山下暁朗
- Organizer
  第43回　日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20H03438
[Presentation] 医学・生物学的観点からのmRNA翻訳制御の新展開2019
- Author(s)
  藤原俊伸, 山下暁朗
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K22601
[Presentation] Scyl2 inhibits Adenovirus release from host cells.2019
- Author(s)
  2)Masaru Shimada, Akio Yamashita, Akiko Okayama, Hisashi Hirano, Nobuhisa Mizuki, Kenji Okuda.
- Organizer
  第６７回日本ウイルス学会
- Data Source
  KAKENHI-PROJECT-17K11288
[Presentation] PI3 kinase様タンパク質リン酸化酵素SMG1によるアミノ酸飢餓応答依存的遺伝子発現制御2019
- Author(s)
  山下暁朗
- Organizer
  第21回日本RNA学会年会
- Data Source
  KAKENHI-PROJECT-19K22601
[Presentation] PI3 kinase様タンパク質リン酸化酵素SMG1による酸化ストレス依存的なNRF2活性制御機構の解析2019
- Author(s)
  藤川由美子, 山下暁朗, 大貫哲男, 鈴木香絵, 青柳杏子, 黒澤瞳, 廣瀬博子, 永井陽子, 上村博司, 吉田稔, 高橋秀尚, 大野茂男
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K22601
[Presentation] PI3 kinase様タンパク質リン酸化酵素SMG1によるストレス応答統御機構2019
- Author(s)
  山下暁朗
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K22601
[Presentation] PI3-kinase related kinase SMG1 and DNA-PKcs directly phosphorylate and regulate NRF2 in response to oxidative stress.2018
- Author(s)
  山下暁朗
- Organizer
  「新生鎖の生物学」合同国際シンポジウム Proteins : from the Cradle to the Grave
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05671
[Presentation] SMG1によるNMDとストレス応答統御機構の解析.2018
- Author(s)
  山下暁朗
- Organizer
  第7回さきがけ「RNAと生体機能」研究会
- Data Source
  KAKENHI-PUBLICLY-17H05671
[Presentation] Novel Receptor Binding Protein ATRAP in the Regulation of Renal Sodium Reabsorption and Blood Pressure Response.2018
- Author(s)
  Kouichi Tamura, Ryu Kobayashi, Kengo Azushima, Kazushi Uneda, Sona Haku, Kohji Ohki, Kotaro Haruhara, Sho Kinguchi, Masato Ohsawa, Shin-ichiro Masuda, Miyuki Matsuda, Akio Yamashita, Hiromichi Wakui.
- Organizer
  Technical Session 1A: Salt and Cardiovascular Health. World Salt Symposium 2018: Salt of the Earth
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02735
[Presentation] Proximal tubule Angiotensin II Type 1 Receptor-associated Protein Regulates Kidney Aging and Lifespan through Sirtuin1-mediated Pathway.2018
- Author(s)
  17.Takahiro Yamaji, Kazushi Uneda, Shingo Urate, Takayuki Yamada, Sho Kinguchi, Sona Haku, Kotaro Haruhara, Kohji Ohki, Ryu Kobayashi, Kengo Azushima, Hiromichi Wakui, Yoshiyuki Toya, Akio Yamashita, Kouichi Tamura.
- Organizer
  The 51th Annual Meeting & Scientific Exposition of American Society of Nephrology (ASN Kidney Week 2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02735
[Presentation] PI3 kinase様タンパク質リン酸化酵素SMG1による酸化ストレス応答制御：SMG1によるNRF2活性制御機構の解析2018
- Author(s)
  藤川由美子, 山下暁朗, 大貫哲男, 鈴木香絵, 青柳杏子, 黒澤瞳, 廣瀬博子, 永井陽子, 上村博司, 吉田稔, 髙橋秀尚, 大野茂男
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K19665
[Presentation] PI3 kinase様タンパク質リン酸化酵素SMG1による酸化ストレス応答制御：SMG1によるNRF2活性制御機構の解析.2018
- Author(s)
  藤川由美子, 山下暁朗, 大貫哲男, 鈴木香絵, 青柳杏子, 黒澤瞳, 廣瀬博子, 永井陽子, 上村博司, 吉田稔, 髙橋秀尚, 大野茂男
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PUBLICLY-17H05671
[Presentation] The human papillomavirus E6 protein targets apoptosis-inducing factor (AIF) for degradation2018
- Author(s)
  Masaru Shimada, Akio Yamashita, Motohide Ichino, Takao Kinjo, Kenji Okuda.
- Organizer
  2nd International Conference on Oncology and Radiology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11288
[Presentation] SMG1によるNMDとストレス応答統御機構の解析2018
- Author(s)
  山下暁朗
- Organizer
  第7回さきがけ「RNAと生体機能」研究会
- Data Source
  KAKENHI-PROJECT-17K19665
[Presentation] PI3 kinase様タンパク質リン酸化酵素SMG1によるアミノ酸飢餓応答依存的遺伝子発現制御2018
- Author(s)
  山下暁朗
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K19665
[Presentation] PI3 kinase様タンパク質リン酸化酵素SMG1によるアミノ酸飢餓応答依存的遺伝子発現制御.2018
- Author(s)
  山下暁朗
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PUBLICLY-17H05671
[Presentation] PI3-kinase related kinase SMG1 and DNA-PKcs directly phosphorylate and regulate NRF2 in response to oxidative stress.2018
- Author(s)
  山下暁朗
- Organizer
  京都大タンパク質動態研究所・新学術領域「新生鎖の生物学」合同国際シンポジウム Proteins : from the Cradle to the Grave
- Data Source
  KAKENHI-PROJECT-17K19665
[Presentation] PI3 kinase様タンパク質リン酸化酵素SMG1阻害による抗腫瘍効果の解析2017
- Author(s)
  藤川由美子, 山下暁朗, 大貫哲男, 鈴木香絵, 青柳杏子, 黒澤瞳, 廣瀬博子, 永井陽子, 上村博司, 吉田稔, 大野茂男
- Organizer
  生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-17K19665
[Presentation] ATRAPはアンジオテンシンII1型受容体非依存性の機序により腎老化および寿命を制御する2017
- Author(s)
  畝田一司, 涌井広道, 前田晃延, 小豆島健護, 白善雅, 小林竜, 大城光二, 春原浩太郎, 金口翔, 山下暁朗, 田村功一
- Organizer
  第60回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-17K09313
[Presentation] PI3 kinase様タンパク質リン酸化酵素SMG1による新たな転写後制御機構の発見2017
- Author(s)
  山下暁朗, 佐藤由典, 黒澤瞳, 廣瀬博子, 青柳杏子, 永井陽子, 大野茂男
- Organizer
  生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-17K19665
[Presentation] 新規aPKC結合タンパクp200による上皮細胞極性の調節機構2017
- Author(s)
  佐々木和教, 麹谷典子, 廣瀬博子, 吉濱陽平, 高柳亜由美, 山下暁朗, 平野久, 大野茂男
- Organizer
  生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-17K19665
[Presentation] 新規aPKC結合タンパクp200による上皮細胞極性の調節機構2017
- Author(s)
  佐々木和教, 麹谷典子, 廣瀬博子, 吉濱陽平, 高柳亜由美, 山下暁朗, 平野久, 大野茂男
- Organizer
  生命科学系学会合同年次大会
- Data Source
  KAKENHI-PUBLICLY-17H05671
[Presentation] PI3 kinase様タンパク質リン酸化酵素SMG1による新たな転写後制御機構の発見2017
- Author(s)
  山下暁朗, 佐藤由典, 黒澤瞳, 廣瀬博子, 青柳杏子, 永井陽子, 大野茂男
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-15H04331
[Presentation] PI3 kinase様タンパク質リン酸化酵素SMG1阻害による抗腫瘍効果の解析2017
- Author(s)
  藤川由美子, 山下暁朗, 大貫哲男, 鈴木香絵, 青柳杏子, 黒澤瞳, 廣瀬博子, 永井陽子, 上村博司, 吉田稔, 大野茂男
- Organizer
  生命科学系学会合同年次大会
- Data Source
  KAKENHI-PUBLICLY-17H05671
[Presentation] 新規aPKC結合タンパクp200による上皮細胞極性の調節機構2017
- Author(s)
  佐々木和教, 麹谷典子, 廣瀬博子, 吉濱陽平, 高柳亜由美, 山下暁朗, 平野久, 大野茂男
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-15H04331
[Presentation] PI3 kinase様タンパク質リン酸化酵素SMG1阻害による抗腫瘍効果の解析：SMG1によるNRF2活性制御の発見2017
- Author(s)
  藤川由美子, 山下暁朗, 大貫哲男, 鈴木香絵, 青柳杏子, 黒澤瞳, 廣瀬博子, 永井陽子, 上村博司, 吉田稔, 大野茂男
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-15H04331
[Presentation] PI3 kinase様タンパク質リン酸化酵素SMG1による新たな転写後制御機構の発見2017
- Author(s)
  山下暁朗, 佐藤由典, 黒澤瞳, 廣瀬博子, 青柳杏子, 永井陽子, 大野茂男
- Organizer
  生命科学系学会合同年次大会
- Data Source
  KAKENHI-PUBLICLY-17H05671
[Presentation] Highly sensitive reporter system for post-transcriptional gene expression regulation.2016
- Author(s)
  14.Yasuda A, Aoyagi K, Nakamura Y, Hirose H, Kurosawa H, Ohno S, Yamashita A.
- Organizer
  The 21nd Annual Meeting of the RNA Society
- Place of Presentation
  国立京都国際会館（京都府京都市）
- Year and Date
  2016-06-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04331
[Presentation] 高精度転写後制御レポーターシステムの構築と検証2016
- Author(s)
  安田篤史、山下暁朗、青柳杏子、中村良恵、廣瀬博子、黒澤瞳、大野茂男
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  横浜パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15H04331
[Presentation] Molecular mechanism of mammalian nonsense-mediated mRNA decay.2016
- Author(s)
  Yamashita A.
- Organizer
  RNA2016 satellite-symposium 'Nascent biology and ribosome function'
- Place of Presentation
  京都大学芝蘭会館稲森ホール（京都府京都市）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04331
[Presentation] PI3 kinase様タンパク質リン酸化酵素SMG1による転写後制御2016
- Author(s)
  16.山下暁朗、佐藤由典、黒澤瞳、廣瀬博子、中村良恵、青柳杏子、武石知子、安田篤史、大野茂男
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15H04331
[Presentation] 動物培養細胞を用いた感度転写後制御モニタリングシステムの構築2015
- Author(s)
  山下暁朗、安田篤史、青柳杏子、中村良恵、廣瀬博子、黒澤瞳、大野茂男
- Organizer
  第37回日本分子生物学会年会・第87回日本生化学会大会合同大会
- Place of Presentation
  神戸商工会議所（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15H04331
[Presentation] 高感度転写後制御レポーター導入システムの構築と検証2015
- Author(s)
  安田篤史、山下暁朗、青柳杏子、中村良恵、廣瀬博子、黒澤瞳、大野茂男
- Organizer
  第37回日本分子生物学会年会・第87回日本生化学会大会合同大会
- Place of Presentation
  神戸国際展示場（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15H04331
[Presentation] RNA品質管理機構を介した遺伝子発現制御.2015
- Author(s)
  山下暁朗
- Organizer
  野本明男先生追悼記念シンポジウム
- Place of Presentation
  ラフォーレ修善寺(静岡県伊東市)
- Year and Date
  2015-01-11
- Data Source
  KAKENHI-PROJECT-23687025
[Presentation] mRNA監視機構分子機構解析とその応用.2014
- Author(s)
  山下暁朗
- Organizer
  「RNAと生体機能」第3回懇話会
- Place of Presentation
  ラフォーレ伊藤(静岡県伊東市)
- Year and Date
  2014-10-26
- Data Source
  KAKENHI-PROJECT-23687025
[Presentation] 異常終止コドン依存的mRNA分解機構におけるSMG-1とUPF1の活性制御機構.2014
- Author(s)
  山下暁朗, 内山晃子, 黒澤瞳, 中村良恵, 青柳杏子, 片岡直行, 大野茂男
- Organizer
  第37回　日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市)
- Year and Date
  2014-11-25
- Data Source
  KAKENHI-PROJECT-23687025
[Presentation] An efficient affinity purification method for interaction proteomics in mammalian cells.2013
- Author(s)
  Yamashita A, Kurosawa H, Hirano H, Ohno S
- Organizer
  HUPO 12th Annual World Congress
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市)
- Year and Date
  2013-09-16
- Data Source
  KAKENHI-PROJECT-23687025
[Presentation] Specific inhibition of SMG-8 rescues effectively the mutant phenotypes exacerbated by nonsense-mediated mRNA decay.2013
- Author(s)
  Akio Yamashita
- Organizer
  RNA and Biofunctions Meeting
- Place of Presentation
  ホテルレオパレス博多（福岡県）
- Year and Date
  2013-01-11
- Data Source
  KAKENHI-PUBLICLY-23112718
[Presentation] Specific inhibition of SMG-8 rescues effectively the mutant phenotypes exacerbated by nonsense mediated mRNA decay.2013
- Author(s)
  Yamashita, A.
- Organizer
  RNA and Biofunctions Meeting
- Place of Presentation
  ホテルレオパレス博多（福岡県）
- Data Source
  KAKENHI-PLANNED-21115004
[Presentation] p50 stabilizes the cell surface E-cadherin and regulates development and maturation of tight Junctions through the PAR complex.2013
- Author(s)
  Fujikawa Y, Harita Y, Hirose T, Yamashita A, Sasaki K, Hirano H, Ohno S
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド(兵庫県神戸市)
- Year and Date
  2013-12-05
- Data Source
  KAKENHI-PROJECT-23687025
[Presentation] Specific inhibition of SMG-8 rescues effectively the mutant phenotypes exacerbated by nonsense-mediated mRNA decay.2012
- Author(s)
  Akio Yamashita
- Organizer
  CSHL meeting 2012 transnational control
- Place of Presentation
  Cold Spring Harbor, USA
- Year and Date
  2012-09-05
- Data Source
  KAKENHI-PUBLICLY-23112718
[Presentation] mRNA surveillance approaches clinic2012
- Author(s)
  山下暁朗
- Organizer
  第14回日本RNA学会年会
- Place of Presentation
  川内萩ホール（宮城県）
- Data Source
  KAKENHI-PLANNED-21115004
[Presentation] PIKKファミリーキナーゼSMG-1の活性制御とmRNA監視機構2012
- Author(s)
  山下暁朗,黒澤瞳,大野茂男
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場（福岡県）
- Data Source
  KAKENHI-PLANNED-21115004
[Presentation] mRNA surveillance approaches clinic.2012
- Author(s)
  山下暁朗
- Organizer
  第14回日本RNA学会年会
- Place of Presentation
  川内萩ホール（宮城県）
- Year and Date
  2012-07-19
- Data Source
  KAKENHI-PUBLICLY-23112718
[Presentation] Translation timings determine the density of interferon-beta mRNA stability2012
- Author(s)
  安部開人,石上友章,Ann-Bin Shyu,大野茂男,梅村敏,山下暁朗
- Organizer
  The 22nd CDB meeting - RNA
- Place of Presentation
  理化学研究所発生再生科学総合研究センター（兵庫県）
- Data Source
  KAKENHI-PLANNED-21115004
[Presentation] mRNA surveillance approaches clinic2012
- Author(s)
  山下暁朗
- Organizer
  第12回蛋白質科学学会年会
- Place of Presentation
  名古屋国際会議場（愛知県）
- Invited
- Data Source
  KAKENHI-PLANNED-21115004
[Presentation] mRNA surveillance approaches clinic.2012
- Author(s)
  山下暁朗
- Organizer
  第12回蛋白質科学学会年会
- Place of Presentation
  名古屋国際会議場（愛知県）
- Year and Date
  2012-06-21
- Invited
- Data Source
  KAKENHI-PUBLICLY-23112718
[Presentation] Transcriptional timing determines the stability of interferon-beta mRNA2012
- Author(s)
  安部開人,石上友章,Ann-Bin Shyu,大野茂男,梅村敏,山下暁朗
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場（福岡県）
- Data Source
  KAKENHI-PLANNED-21115004
[Presentation] PIKKファミリーキナーゼSMG-1の活性制御とmRNA監視機構2012
- Author(s)
  山下暁朗
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場（福岡県）
- Year and Date
  2012-12-13
- Data Source
  KAKENHI-PUBLICLY-23112718
[Presentation] Specific inhibition of SMG-8 rescues effectively the mutant phenotypes exacerbated by nonsense-mediated mRNA decay without cell toxicity.2012
- Author(s)
  Yamashita A, Usuki F, Ohno S
- Organizer
  2012 CSHL Meeting on Translational Control
- Place of Presentation
  Cold Spring Harbor Laboratory（NY, USA）
- Data Source
  KAKENHI-PROJECT-22247030
[Presentation] Specific inhibition of SMG-8 rescues effectively the mutant phenotypes exacerbated by nonsense-mediated mRNA decay.2012
- Author(s)
  Yamashita, A, Usuki, F. Ohno, S.
- Organizer
  CSHL meeting 2012 transnational control
- Place of Presentation
  old Spring Harbor, USA
- Data Source
  KAKENHI-PLANNED-21115004
[Presentation] The SMG-1 mediated N- and C-terminal phosphorylation of Upf1 create binding platform of SMG-6 and the SMG5:SMG-7 complex during nonsense-mediated mRNA decay2011
- Author(s)
  Yamashita A, Okada-Katsuhata Y, Kutsuzawa K, Izumi N, Hirahara F, Ohno S
- Organizer
  第16回国際RNA学会年会
- Place of Presentation
  京都国際会館(京都府)
- Year and Date
  2011-06-17
- Data Source
  KAKENHI-PROJECT-23687025
[Presentation] The role of SMG-1 in nonsense-mediated mRNA decay2011
- Author(s)
  Yamashita A
- Organizer
  RNA Asia Studies
- Place of Presentation
  Fullon Hot Spring Kesort at Tamsui (Taiwan)
- Year and Date
  2011-11-11
- Data Source
  KAKENHI-PROJECT-23687025
[Presentation] The SMG-1 mediated N- and C-terminal phosphorylation of Upf1 create binding platform of SMG-6 and the SMG5:SMG-7 complex during nonsense-mediated mRNA decay2011
- Author(s)
  Yamashita A, Okada-Katsuhata Y, Kutsuzawa K, Izumi N, Hirahara F, Ohno S
- Organizer
  第16回国際RNA学会年会
- Place of Presentation
  京都国際会館(京都府)
- Year and Date
  2011-06-17
- Data Source
  KAKENHI-PUBLICLY-23112718
[Presentation] 動物細胞におけるmRNA監視機構の分子機構の研究2011
- Author(s)
  山下暁朗
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川県)(招待講演)
- Year and Date
  2011-12-15
- Data Source
  KAKENHI-PROJECT-23687025
[Presentation] The role of SMG-1 in nonsense-mediated mRNA decay2011
- Author(s)
  Yamashita A
- Organizer
  RNA Asia Studies
- Place of Presentation
  Fullon Hot Spring resort at Tamsui (Taiwan)
- Year and Date
  2011-11-11
- Data Source
  KAKENHI-PUBLICLY-23112718
[Presentation] 動物細胞におけるmRNA監視機構の分子機構の研究2011
- Author(s)
  山下暁朗
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川県)(招待講演)
- Year and Date
  2011-12-15
- Data Source
  KAKENHI-PUBLICLY-23112718
[Presentation] IL-6遺伝子発現におけるmRNA転写後制御機構の解析2010
- Author(s)
  安部開人、山下暁朗、馬場しほ、岡田一平、石上友章、梁明秀
- Organizer
  BMB2010
- Place of Presentation
  神戸、ポートアイランド
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PROJECT-21790289
[Presentation] HSP90 regulates PIKK family together with the conserved protein complexes.2010
- Author(s)
  Yamashita A, Izumi N, Ohno S.
- Organizer
  Cold spring harbor laboratory meeting 2010 translational control.
- Data Source
  KAKENHI-PROJECT-21790289
[Presentation] mRNA監視機構と疾患.2010
- Author(s)
  山下暁朗.
- Organizer
  日本環境変異原学会第39回大会
- Place of Presentation
  (招待講演)
- Data Source
  KAKENHI-PROJECT-21790289
[Presentation] RUVBL1/RUVBL2複合体によるNMD制御.2010
- Author(s)
  山下暁朗、泉奈津子、岩松明彦、平野久、大野茂男.
- Organizer
  第12回日本RNA学会年会.第12回日本RNA学会年会.
- Data Source
  KAKENHI-PROJECT-21790289
[Presentation] HSP90 regulates PIKK family together with the conserved protein complexes.2010
- Author(s)
  山下暁朗、泉奈津子、大野茂男
- Organizer
  Cold spring harbor laboratory meeting translational control
- Place of Presentation
  New York, USA
- Year and Date
  2010-09-15
- Data Source
  KAKENHI-PROJECT-21790289
[Presentation] Methylmercury causes oxidative stress through its posttranscriptional effect on antioxidant selenoenzymes.2010
- Author(s)
  Usuki F, Yamashita A, Fujimura M
- Organizer
  XVII^<th> International Congress of Neuropathology
- Place of Presentation
  Austria, Salzburg
- Data Source
  KAKENHI-PROJECT-20591015
[Presentation] mRNA品質管理機構制御因子SMG-1の構想と生理機能2010
- Author(s)
  山下暁朗, Ernesto A P, Israel F S, 番場由美, 星野耕二, 上村博司, Oscar L I, 大野茂男
- Organizer
  第33回日本分子生物学会年会第83回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PROJECT-22247030
[Presentation] RUVBL1/RUVBL2複合体によるNMD制御2010
- Author(s)
  山下暁朗、泉奈津子、岩松明彦、平野久、大野茂男
- Organizer
  第12回日本RNA学会年会
- Place of Presentation
  東京、一橋記念講堂
- Year and Date
  2010-07-27
- Data Source
  KAKENHI-PROJECT-21790289
[Presentation] IL-6遺伝子発現におけるmRNA転写後制御機構の解析.2010
- Author(s)
  安部開人、山下暁朗、馬場しほ、岡田一平、石上友章、梁明秀.
- Organizer
  BMB2010.
- Data Source
  KAKENHI-PROJECT-21790289
[Presentation] 微量RNAからの次世代シークエンスライブラリー構築法の改善2010
- Author(s)
  馬場しほ, 山下暁朗, 大野茂男
- Organizer
  第33回日本分子生物学会年会第83回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-22247030
[Presentation] 微量RNAからの次世代シークエンサーライブラリー構築法の改善2010
- Author(s)
  馬場しほ、山下暁朗、大野茂男
- Organizer
  BMB2010
- Place of Presentation
  神戸、ポートアイランド
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-21790289
[Presentation] mRNA監視機構制御因子SMG-1の構造と生理機能.2010
- Author(s)
  山下暁朗.
- Organizer
  BMB2010.
- Data Source
  KAKENHI-PROJECT-21790289
[Presentation] RNAポリメラーゼサブニットRPB5はNMDに関与する2010
- Author(s)
  泉奈津子、山下暁朗、倉田理恵、平野久、大野茂男
- Organizer
  第12回日本RNA学会年会
- Place of Presentation
  東京、一橋記念講堂
- Year and Date
  2010-07-27
- Data Source
  KAKENHI-PROJECT-21790289
[Presentation] RNAポリメラーゼサブニットRPB5はNMDに関与する.2010
- Author(s)
  泉奈津子、山下暁朗、倉田理恵、平野久、大野茂男.
- Organizer
  第12回日本RNA学会年会.第12回日本RNA学会年会.
- Data Source
  KAKENHI-PROJECT-21790289
[Presentation] mRNA監視機構制御因子SMG-1の構造と生理機能2010
- Author(s)
  山下暁朗
- Organizer
  BMB2010
- Place of Presentation
  神戸、ポートアイランド
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-21790289
[Presentation] Apoptosis-Stimulating Protein of p53 (ASPP2) isinvolved in the PAR Complex to Regulate Epithelial Cell Polarity.2010
- Author(s)
  叢偉立, 廣瀬智威, 山下暁朗, 水野恵子, 張田豊, 平野久, 大野茂男
- Organizer
  第62回日本細胞生物学会大会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2010-05-19
- Data Source
  KAKENHI-PROJECT-22247030
[Presentation] 微量RNAからの次世代シークエンサーライブラリー構築法の改善.2010
- Author(s)
  馬場しほ、山下暁朗、大野茂男.
- Organizer
  BMB2010.
- Data Source
  KAKENHI-PROJECT-21790289
[Presentation] mRNA監視機構と疾患2010
- Author(s)
  山下暁朗
- Organizer
  日本環境変異原学会第39回大会
- Place of Presentation
  筑波、つくば国際会議場(招待講演)
- Year and Date
  2010-11-17
- Data Source
  KAKENHI-PROJECT-21790289
[Presentation] 異常終止コドン認識複合体とその制御メカニズム.2009
- Author(s)
  山下暁朗, 泉奈津子, 勝畑有紀子, 沓沢慧, 番場由美, 大野茂男.
- Organizer
  第11回日本RNA学会年会.
- Data Source
  KAKENHI-PROJECT-21790289
[Presentation] THE REMODELING OF MRNA SURVEILLANCE COMPLEX DURING NONSENSE-MEDIATED MRNA DECAY2009
- Author(s)
  Yamashita A, Izumi N, Okada-Katsuhata Y, Kutsuzawa K, Muramatsu R, Sarri B, Iwamatsu A, Hirano H, Hirahata F, Anderson P, Ohno S.
- Organizer
  Cold spring harbor laboratory meeting 2009mRNA processing
- Place of Presentation
  New York。 USA
- Year and Date
  2009-08-20
- Data Source
  KAKENHI-PROJECT-21790289
[Presentation] 異常終止コドン認識複合体とその制御メカニズム.2009
- Author(s)
  山下暁朗, 泉奈津子, 勝畑有紀子, 沓沢慧, 番場由美, 大野茂男.
- Organizer
  第11回日本RNA学会年会
- Place of Presentation
  新潟
- Year and Date
  2009-07-27
- Data Source
  KAKENHI-PROJECT-21790289
[Presentation] THE REMODELING OF MRNA SURVEILLANCE COMPLEX DURING NONSENSE-MEDIATED MRNA DECAY.2009
- Author(s)
  Yamashita A, Izumi N, Okada-Katsuhata Y, Kutsuzawa K, Muramatsu R, Sarri B, Iwamatsu A, Hirano H, Hirahata F, Anderson P, Ohno S.
- Organizer
  Cold spring harbor laboratory meeting 2009 mRNA processing
- Place of Presentation
  New York
- Data Source
  KAKENHI-PROJECT-21790289
[Presentation] TRANSLATION TERMINATION COMPLEX DURING NONSENSE- MEDIATED MRNA DECAY.2008
- Author(s)
  Yamashita A, Izumi N, Kashima I, Katsuhata Y, Muramatsu R, Ohno S.
- Organizer
  Cold spring harbor laboratory meeting 2008 Translational control
- Place of Presentation
  New York
- Data Source
  KAKENHI-PROJECT-19770151
[Presentation] The formation of SMG-1 : Upfl : eRF1 : eRF3 complex (SURF) on ribosomes precedes translation-dependent-Upfl phosphorylatio n during nonsense-mediated mRNA decay2008
- Author(s)
  Yamashita A, Kashima I, Izumi N, Katsuhata Y, Muramatsu R, Ohno S
- Organizer
  THE 21st NAITO CONFERENCE "Nuclea Dynamics and RNA [I]
- Place of Presentation
  Yamanashi, Japan
- Year and Date
  2008-06-26
- Data Source
  KAKENHI-PROJECT-19770151
[Presentation] TRANSLATION TERMINATION COMPLEX DURING NONS ENSE- MEDIATED MRNA DECAY2008
- Author(s)
  Yamashita A, Izumi N, Kashima I, Katsuhata Y, Muramatsu R. Ohno S
- Organizer
  2008 Cold spring harver labatory meeting on translational control
- Place of Presentation
  New York, USA
- Year and Date
  2008-09-03
- Data Source
  KAKENHI-PROJECT-19770151
[Presentation] The formation of SMG-1 : Upf1 : eRF1 : eRF3 complex (SURF) on ribosomes precedes translation dependent Upf1 phosphorylation during nonsense-mediated mRNA decay2008
- Author(s)
  Yamashita A, Kashima I, Izumi N, Katsuhata Y, Muramatsu R, Ohno S
- Organizer
  THE 21st NAITO CONFERENCE Nuclear Dynamics and RNA [I]
- Place of Presentation
  Yamanashi
- Year and Date
  2008-06-26
- Data Source
  KAKENHI-PROJECT-19770151
[Presentation] Ullrich病細胞機能を回復させるNMD(nonsense-mediated-mediated mRNA decay)抑制分子的探索2007
- Author(s)
  臼杵扶佐子、山下暁朗、樋口逸郎、大野茂男
- Organizer
  第48回日本神経学会総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-18590969
[Presentation] 翻訳依存的なmRNA監視複合体形成および再構成がUpf1リン酸化を誘導する2007
- Author(s)
  山下暁朗, 泉奈津子, 鹿島勲, 森田智子, 村松玲子
- Organizer
  第30回日本分子生物学会年会〜第80回日本生化学会大会合同大会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2007-12-15
- Data Source
  KAKENHI-PROJECT-19770151
[Presentation] Search for nonsense-mediated mRNA decay(NMD) components, specific inhibition of which rescues effectively the phenotype of genetic diseases exacerbated by NMD2007
- Author(s)
  Usuki F, Yamashita A, Higuchi J, Ohno S
- Organizer
  48th Annual Meeting of the Japanese Society of Neurology
- Place of Presentation
  Nagoya
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590969
[Presentation] The SMG-1:SMG-8:p60 Complex Regulated Phosphorylation Of Upfl Is Required For The Dissociation Of eRFs From mRNA Surveillance Comp lex During Nonsense-mediated mRNA decay2007
- Author(s)
  Yamashita A, Kashima I, Izumi N, Ohnishi T, Anderson P, Ohno S
- Organizer
  第12回国際RNA学会年会
- Place of Presentation
  University of Wisconsin,Madison
- Year and Date
  2007-06-03
- Data Source
  KAKENHI-PROJECT-19770151
[Presentation] Ullrich病細胞機能を回復させるNMD(nonsense-mediated mRNA decay)抑制分子の探索2007
- Author(s)
  臼杵扶佐子、山下暁朗、樋口逸郎、大野茂男
- Organizer
  第48回日本神経学会総会
- Place of Presentation
  名古屋
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590969
[Presentation] The SMG-1:SMG-8:p60 Complex Regulated Phosphorylation Of Upfl Is Required For The Dissociation Of eRFs From mRNA Surveillance Complex During Nonsense-mediated mRNA decay2007
- Author(s)
  Yamashita A, Izumi N, Kashima I, Ohnishi T, Anderson P, Ohno S
- Organizer
  第9回日本RNA学会年会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2007-07-31
- Data Source
  KAKENHI-PROJECT-19770151
[Presentation] The SMG-1 : SMG-8 : p60 Complex Regulated Phosphorylation Of Upf1 Is Required For The Dissociation Of eRFs From mRNA Surveillance Complex During Nonsense-mediated mRNA decay.2007
- Author(s)
  Yamashita A, Izumi N, Kashima I, Ohnishi T, Anderson P, Ohno S
- Organizer
  第9回日本RNA学会年会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2007-07-31
- Data Source
  KAKENHI-PROJECT-19770151
[Presentation] 翻訳依存的なmRNA監視複合体形成および再構成がUpf1リン酸化を誘導する2007
- Author(s)
  山下暁朗,泉奈津子,鹿島勲,森田智子,村松玲子,大野茂男
- Organizer
  BMB2007-第30回日本分子生物学会年会・第80回日本生化学会大会合同大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19770151
[Presentation] The SMG-1 : SMG-8 : p60 Complex Regulated Phosphorylation Of Upf1 Is Required For The Dissociation Of eRFs From mRNA Surveillance Complex During Nonsense-mediated mRNA decay.2007
- Author(s)
  Yamashita A, Kashima I, Izumi N, Ohnishi T, Anderson P, Ohno S.
- Organizer
  第12回国際RNA学会年会
- Place of Presentation
  Wisconsin
- Data Source
  KAKENHI-PROJECT-19770151
[Presentation] Inhibition of nonsense-mediated mRNA decay rescues the phenotype of Ullrich's disease fibroblasts.2006
- Author(s)
  Yamashita A, Usuki F, Kashima I, Izumi N, Higuchi I, Osame M, Ohno S
- Organizer
  8th Annual Meeting of the RNA Society of Japan
- Place of Presentation
  Awaji
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590969
[Presentation] Inhibition of nonsense-mediated mRNA decay rescues the phenotype of Ullrich's disease fibroblasts2006
- Author(s)
  Yamashita A, Usuki F, Kashima I, Izumi N, Higuchi I, Osame M, Ohno S
- Organizer
  第8回日本RNA学会
- Place of Presentation
  淡路
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590969
[Presentation] p50 Regulates Epithelial Cell Polarity by Inhibiting E-cadherin endocytosis.
- Author(s)
  Fujikawa Y, Hirose T, Harita Y, Sasaki K, Yamashita K, Yamashita A, Hirano H, Ohno S
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場・マリンメッセ福岡（福岡県）
- Data Source
  KAKENHI-PROJECT-22247030
[Presentation] 動物細胞におけるmRNA監視機構の分子機構の研究
- Author(s)
  山下暁朗
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜 (神奈川県)
- Invited
- Data Source
  KAKENHI-PLANNED-21115004
[Presentation] mRNA surveillance approaches clinic.
- Author(s)
  山下暁朗
- Organizer
  第14回日本RNA学会年会
- Place of Presentation
  川内萩ホール（宮城県）
- Data Source
  KAKENHI-PROJECT-23687025
[Presentation] Specific inhibition of SMG-8 rescues effectively the mutant phenotypes exacerbated by nonsensemediated mRNA decay.
- Author(s)
  Yamashita, A.
- Organizer
  CSHL meeting 2012 transnational control
- Place of Presentation
  Cold Spring Harbor, USA
- Data Source
  KAKENHI-PROJECT-23687025
[Presentation] PIKKファミリーキナーゼSMG-1の活性制御とmRNA監視機構
- Author(s)
  山下暁朗
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場（福岡県）
- Data Source
  KAKENHI-PROJECT-23687025
[Presentation] A novel microtubule binding protein, MARKAP1, cooperates with PAR-1 for the development of the lateral microtubule bundles in epithelial cells.
- Author(s)
  Akitsu M, Satoh Y, Amano Y, Yamashita K, Yamashita A, Maki T, Hayashi I, Hirano H, Ohno S, Suzuki A
- Organizer
  American Society for Cell Biology ( ASCB) 2012 Annual Meeting
- Place of Presentation
  Moscone Center, San Francisco（San Francisco, USA）
- Data Source
  KAKENHI-PROJECT-22247030
[Presentation] Specific inhibition of SMG-8 rescues effectively the mutant phenotypes exacerbated by nonsensemediated mRNA decay.
- Author(s)
  Yamashita, A.
- Organizer
  RNA and Biofunctions Meeting
- Place of Presentation
  ホテルレオパレス博多（福岡県）
- Data Source
  KAKENHI-PROJECT-23687025
[Presentation] Transcriptional Timing Determines the Stability of Interferon-beta mRNA.
- Author(s)
  Abe K, Ishigami T, Ann-Bin S, Ohno S, Umemura S, Yamashita A
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場・マリンメッセ福岡（福岡県）
- Data Source
  KAKENHI-PROJECT-22247030
[Presentation] The SMG-1 mediated N- and C-terminal phosphorylation of Upf1 create binding platform of SMG-6 and the SMG5:SMG-7 complex during nonsense-mediated mRNA decay.
- Author(s)
  Yamashita A. et al.
- Organizer
  第16回国際RNA学会年会
- Place of Presentation
  京都国際会館（京都府）
- Data Source
  KAKENHI-PLANNED-21115004
[Presentation] ガン抑制遺伝子Lglは、VprBPと結合することによって、単層の上皮構造を維持している.
- Author(s)
  山下和成, 井出真理子, 村松玲子, 鈴木厚, 平野久, 大野茂男
- Organizer
  第63回日本細胞生物学会大会
- Place of Presentation
  北海道大学　クラーク会館、学術交流会館(北海道)
- Data Source
  KAKENHI-PROJECT-22247030
[Presentation] mRNA surveillance approaches clinic.
- Author(s)
  山下暁朗
- Organizer
  第12回蛋白質科学学会年会
- Place of Presentation
  名古屋国際会議場（愛知県）
- Invited
- Data Source
  KAKENHI-PROJECT-23687025
[Presentation] SMG-1, PIKK Family Kinase, Regulates mRNA Surveillance.
- Author(s)
  Yamashita A, Kurosawa H, Ohno S
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場・マリンメッセ福岡（福岡県）
- Data Source
  KAKENHI-PROJECT-22247030
[Presentation] The role of SMG-1 in nonsense-mediated mRNA decay
- Author(s)
  Yamashita A.
- Organizer
  RNA Asia Studies
- Place of Presentation
  Fullon Hot Spring Resort at Tamsui (Taiwan)
- Data Source
  KAKENHI-PLANNED-21115004
[Presentation] Analysis of Physiological Function of MARKAP1 in the Cerebellum.
- Author(s)
  Satake T, Hayashi K, Yamashita K, Satoh Y, Ohno S, Suzuki A
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場・マリンメッセ福岡（福岡県）
- Data Source
  KAKENHI-PROJECT-22247030
[Presentation] IL-6 遺伝子発現における mRNA 転写後制御機構の解析.
- Author(s)
  安部開人, 山下暁朗, Ann-Bin Shyu, 石上友章, 大野茂男, 梅村敏
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Data Source
  KAKENHI-PROJECT-22247030

1. USUKI Fusako (50185013)

# of Collaborated Projects: 4 results

# of Collaborated Products: 17 results
2. Wakui Hiromichi (10587330)

# of Collaborated Projects: 4 results

# of Collaborated Products: 8 results
3. TAMURA Kouichi (40285143)

# of Collaborated Projects: 3 results

# of Collaborated Products: 7 results
4. Shimada Masaru (40301452)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. TEI Kumiko (50213327)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. ODA Takeaki (00608523)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. NISHIMURA Yukiko (30514567)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. TOMARI Yukihide (90447368)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. KAGEYAMA Yuji (90335480)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. SUZUKI Takeo (90533125)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. NAKAZAWA Takanobu (00447335)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. WADA Takeshi (90240548)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. SADO Takashi (70321601)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. SIOMI Mikiko (20322745)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. MIYAGAWA Satomi (90291153)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. NAKAGAWA Shinichi (50324679)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. TAKESHITA Fumitaka (40466199)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. OHNO Shigeo (10142027)

# of Collaborated Projects: 1 results

# of Collaborated Products: 24 results
19. HIRAI Syu-ichi (80228759)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. SUZUKI Atsushi (00264606)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
21. AKIMOTO Kazunori (70285104)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. HIROSE Tomonori (20381668)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
23. NAKAYA Masa-aki (70422095)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. SASAKI Kazunori (50438131)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
25. FUJIMURA Masatake (20416564)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 樋口逸郎 (80183573)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 小林竜 (60805612)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
28. 畝田一司 (90780370)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
29. 宮崎智之 (30580724)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. KANAOKA Tomohiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
31. 忻克〓

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
32. 嶋田美穂

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
33. 野田岳志

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
34. 金口翔

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
35. 高橋建造

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
36. 内海大介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
37. 戸谷義幸

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
38. 大澤正人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
39. 金城貴夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
40. 鈴木徹

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
41. 田村智彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
42. 浦手進吾

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Yamashita Akio 山下 暁朗

YAMASHITA Akio 山下 暁朗

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細胞ストレスによるmRNA監視機構抑制の分子機構とがん抗原発現機構の解明Principal Investigator

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Analysis of the inhibition of mRNA surveillancePrincipal Investigator

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Analysis of post-translation termination eventPrincipal Investigator

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Development of basic technology for intractable and rare diseasesPrincipal Investigator

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Development of basic technology for intractable and rare diseasesPrincipal Investigator

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Analysis of the nascent peptide-ribosome complex during amino acid starvation.Principal Investigator

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Post-transcriptional gene expression regulation via mRNA surveillance systemPrincipal Investigator

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Yamashita Akio 山下暁朗

YAMASHITA Akio 山下暁朗