Uchida Satoshi 内田智士

… Alternative Names

UCHIDA Satoshi 内田智士

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Researcher Number	20710726
Other IDs
Affiliation (Current)	2025: 東京科学大学, 総合研究院, 教授 2025: 公益財団法人川崎市産業振興財団(ナノ医療イノベーションセンター), ナノ医療イノベーションセンター, 主幹研究員 2025: 京都府立医科大学, 医学(系)研究科(研究院), 特任教授
Affiliation (based on the past Project Information) *help	2025: 東京科学大学, 難治疾患研究所, 教授 2022 – 2024: 東京医科歯科大学, 難治疾患研究所, 教授 2022: 東京大学, 大学院工学系研究科(工学部), 特任助教 2020 – 2021: 京都府立医科大学, 医学(系)研究科(研究院), 准教授 2016 – 2020: 東京大学, 大学院工学系研究科(工学部), 特任助教 … More 2017: 東京大学, 大学院工学系研究科, 特任助教 2014 – 2015: 東京大学, 医学(系)研究科(研究院), 助教 2013: 東京大学, 医学(系)研究科(研究院), 研究員 Less
Review Section/Research Field	Principal Investigator Medium-sized Section 90:Biomedical engineering and related fields / Basic Section 90120:Biomaterials-related / Biomedical engineering and related fields / Applied pharmacology / Biomedical engineering/Biomaterial science and engineering Except Principal Investigator Broad Section D / Basic Section 90120:Biomaterials-related / Medium-sized Section 90:Biomedical engineering and related fields / Chemistry / Science and Engineering
Keywords	Principal Investigator mRNA医薬 / ペプチド / mRNAワクチン / 炎症 / 核酸医薬 / 高分子ミセル / mRNAデリバリー / 抗アポトーシス因子 / 遺伝子治療 / mRNA導入 … More / 合成高分子 / 単鎖抗体 / 多剤耐性菌 / 吸入 / 薬物動態 / 炎症性疾患 / ペプチド医薬 / ポリエチレングリコール / ダメージ関連分子パターン / 薬物送達システム / ワクチン / RNA工学 / mRNA工学 / 中分子医薬 / 2本鎖mRNA / ガンワクチン / 脂質性ナノ粒子 / 2本鎖RNA / 細胞性免疫 / 遺伝子送達 / リポプレックス / アジュバント / がんワクチン / 薬学 / ナノバイオ / 再生医学 / 骨再生治療 / miRNA / 間葉系幹細胞 / スフェロイド / 再生医療 / 細胞移植治療 / 3次元培養 / 細胞外小胞 / ナノミセル / 下肢虚血性疾患 / 虚血性疾患 / アポトーシス / アポトーシス関連疾患 / 非ウイルス性キャリア / ハイドロダイナミクス法 / 劇症肝炎 / 高分子ナノミセル … More Except Principal Investigator mRNA / ミトコンドリア / 腫瘍血管 / ナノ医療 / DDS / スマートポリマー / LNP / antibody fragments / Immunotherapy / cancer / immunotherapy / nanomedicine / in vivo CAR T / Antibody fragment / Cancer / Polymeric micelles / Nanomedicine / CAR T cells / ナノメディシン / アプタマー / polymeric nanocarrier / hybridization / protein translatiokn / theophylline / triggered translation / theophyline / polymer / aptamer / グルコーストランスポ-ター / 脳―血液関門 / 脳一血液関門 / グルコーストランスポーター / アルツハイマー病 / 脳-血液関門 / 遺伝子治療 / 抗体医薬 / プラスミドDNA / メッセンジャーRNA / アンチセンス核酸 / siRNA / 血液脳関門（BBB） / 薬物送達システム / ポリアミノ酸 / ポリエチレングリコール / 高分子ミセル / ブロック共重合体 Less

mRNA医薬、進化分子工学、深層学習を基盤としたタンパク質間相互作用標的創薬Principal Investigator
- Principal Investigator
  
  内田智士
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  Institute of Science Tokyo
Pioneering Treatment of Antimicrobial Resistance through Nebulization of Single-Chain Antibody mRNAPrincipal Investigator
- Principal Investigator
  
  内田智士
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  Tokyo Medical and Dental University
Activated mRNA delivery system based on core-shell structured LNP with smart polymers
- Principal Investigator
  
  原島秀吉
- Project Period (FY)
  2023 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Review Section
  
  Broad Section D
- Research Institution
  Hokkaido University
Development and therapeutic application of short mRNA therapeutics based on mRNA engineeringPrincipal Investigator
- Principal Investigator
  
  内田智士
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  Tokyo Medical and Dental University
  Kyoto Prefectural University of Medicine
In situ PEGylation of extracellular DNA using functional peptides for anti-inflammatory therapyPrincipal Investigator
- Principal Investigator
  
  Uchida Satoshi
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  Tokyo Medical and Dental University
  Kyoto Prefectural University of Medicine
Cancer immunotherapy by in vivo generation of CAR T cells based on targeted mRNA delivery
- Principal Investigator
  
  Cabral Horacio
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 90120:Biomaterials-related
- Research Institution
  The University of Tokyo
Development of immunostimulatory mRNA and lymphoid tissue-targeting carriers for cancer vaccinePrincipal Investigator
- Principal Investigator
  
  Uchida Satoshi
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 90120:Biomaterials-related
- Research Institution
  Kyoto Prefectural University of Medicine
  The University of Tokyo
Development of mRNA drug with RNA type aptamer conferring cell type specific translation activation function
- Principal Investigator
  
  Cabral Horacio
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  The University of Tokyo
Determination of therapeutic factors using extracellular vesicles secreted from 3D-cultured stem cellsPrincipal Investigator
- Principal Investigator
  
  Uchida Satoshi
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  Biomedical engineering and related fields
- Research Institution
  Kyoto Prefectural University of Medicine
  The University of Tokyo
In vivo suppression of apoptosis signaling using mRNA therapeutics for the treatment of ischemic diseasesPrincipal Investigator
- Principal Investigator
  
  Uchida Satoshi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Applied pharmacology
- Research Institution
  The University of Tokyo
mRNA-based introduction of anti-apoptotic factors using nanomicelle for therapeutic applicationPrincipal Investigator
- Principal Investigator
  
  UCHIDA Satoshi
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  The University of Tokyo
Development of Polymeric Micelles for Brain-Targeted Delivery of Nucleic Acid Drugs to Treat Intractable Neurological Diseases
- Principal Investigator
  
  KATAOKA Kazunori
- Project Period (FY)
  2013 – 2017
- Research Category
  
  Grant-in-Aid for Specially Promoted Research
- Review Section
  
  Science and Engineering
  Chemistry
- Research Institution
  Kawasaki Institute of Industrial Promotion Innovation Center of NanoMedicine
  The University of Tokyo

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 Other

All Journal Article Presentation Book Patent

[Book] Messenger RNA Therapeutics2022
- Author(s)
  Eger Boonstra, Satoshi Uchida, Horacio Cabral
- Total Pages
  446
- Publisher
  Springer International Publishing
- ISBN
  9783031084157
- Data Source
  KAKENHI-PROJECT-21H04962
[Book] 高分子ナノミセルを用いた生体へのin vivo mRNAデリバリー(トランスレーショナルリサーチを支援する遺伝子医学MOOK30号)2016
- Author(s)
  内田智士、位高啓史、片岡一則
- Pages
  119-124
- Total Pages
  300
- Publisher
  株式会社メディカルドゥ
- Data Source
  KAKENHI-PROJECT-25000006
[Book] 高分子ナノミセルを用いた生体へのin vivo mRNAデリバリートランスレーショナルリサーチを支援する遺伝子医学MOOK30号今、着実に実り始めた遺伝子治療－最新研究と今後の展開2016
- Author(s)
  内田智士，位高啓史，片岡一則
- Total Pages
  300
- Publisher
  株式会社メディカルドゥ
- Data Source
  KAKENHI-PROJECT-15K20962
[Book] Nanoparticles in the lung: environmental exposure and drug delivery (Drug and gene delivery in the lungs)2015
- Author(s)
  S. Uchida, K. Itaka, K. Kataoka
- Total Pages
  403
- Publisher
  CRC press, Taylor & Francis Group (Florida, USA)
- Data Source
  KAKENHI-PROJECT-25882011
[Book] Nanoparticles in the lung : environmental exposure and drug delivery(Drug and gene delivery in the lungs)2015
- Author(s)
  S. Uchida, K. Itaka, K. Kataoka
- Total Pages
  403
- Publisher
  CRC press, Taylor & Francis Group(Florida, USA)
- Description
  【発行確定】
- Data Source
  KAKENHI-PROJECT-25000006
[Journal Article] Poly(ethylene Glycol) (PEG)?OligoRNA Hybridization to mRNA Enables Fine‐Tuned Polyplex PEGylation for Spleen‐Targeted mRNA Delivery2024
- Author(s)
  Suzuki Miki、Mochida Yuki、Hori Mao、Hayashi Akimasa、Toh Kazuko、Tockary Theofilus A.、Liu Xueying、Marx Victor、Yokoo Hidetomo、Miyata Kanjiro、Oba Makoto、Uchida Satoshi
- Journal Title
  
  Small Science
  
  Volume: - Issue: 4 Pages: 202300258-202300258
- DOI
  10.1002/smsc.202300258
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23H05451, KAKENHI-PROJECT-21H04962
[Journal Article] mRNA vaccine designs for optimal adjuvanticity and delivery2024
- Author(s)
  Mochida Yuki、Uchida Satoshi
- Journal Title
  
  RNA Biology
  
  Volume: 21 Issue: 1 Pages: 1-27
- DOI
  10.1080/15476286.2024.2333123
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23H05451, KAKENHI-PROJECT-21H04962
[Journal Article] Hydrophobicity Tuning of Cationic Polyaspartamide Derivatives for Enhanced Antisense Oligonucleotide Delivery2024
- Author(s)
  Yum Jongmin、Aulia Fadlina、Kamiya Keisuke、Hori Mao、Qiao Nan、Kim Beob Soo、Naito Mitsuru、Ogura Satomi、Nagata Tetsuya、Yokota Takanori、Uchida Satoshi、Obika Satoshi、Kim Hyun Jin、Miyata Kanjiro
- Journal Title
  
  Bioconjugate Chemistry
  
  Volume: 35 Issue: 2 Pages: 125-131
- DOI
  10.1021/acs.bioconjchem.3c00456
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23H05451, KAKENHI-PROJECT-21H04962
[Journal Article] Ionizable Polymeric Micelles with Phenylalanine Moieties Enhance Intracellular Delivery of Self-Replicating RNA for Long-Lasting Protein Expression In Vivo2024
- Author(s)
  Mixich Lucas、Boonstra Eger、Masuda Keita、Li Shang-Wei、Nakashima Yuki、Meng Fanlu、Sakata Momoko、Goda Tatsuro、Uchida Satoshi、Cabral Horacio
- Journal Title
  
  Biomacromolecules
  
  Volume: 25 Issue: 2 Pages: 1058-1067
- DOI
  10.1021/acs.biomac.3c01102
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23H05451, KAKENHI-PROJECT-21H04962
[Journal Article] Oligosarcosine Conjugation of Arginine-Rich Peptides Improves the Intracellular Delivery of Peptide/pDNA Complexes2023
- Author(s)
  Yokoo Hidetomo、Dirisala Anjaneyulu、Uchida Satoshi、Oba Makoto
- Journal Title
  
  ACS Biomaterials Science & Engineering
  
  Volume: 10 Issue: 2 Pages: 890-896
- DOI
  10.1021/acsbiomaterials.3c01542
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K11841, KAKENHI-PROJECT-21K18062, KAKENHI-PROJECT-22K15257, KAKENHI-PROJECT-23H05451, KAKENHI-PROJECT-21H04962
[Journal Article] An Amphipathic Structure of a Dipropylglycine-Containing Helical Peptide with Sufficient Length Enables Safe and Effective Intracellular siRNA Delivery2023
- Author(s)
  Makoto Oba, Mika Shibuya, Yuto Yamaberi, Hidetomo Yokoo, Satoshi Uchida, Atsushi Ueda, Masakazu Tanaka
- Journal Title
  
  Chemical and Pharmaceutical Bulletin
  
  Volume: 71 Issue: 3 Pages: 250-256
- DOI
  10.1248/cpb.c22-00852
- ISSN
  0009-2363, 1347-5223
- Year and Date
  2023-03-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H04962, KAKENHI-PROJECT-21K19923
[Journal Article] Cap analogs with a hydrophobic photocleavable tag enable facile purification of fully capped mRNA with various cap structures2023
- Author(s)
  Masahito Inagaki, Naoko Abe, Zhenmin Li, Yuko Nakashima, Susit Acharyya, Kazuya Ogawa, Daisuke Kawaguchi, Haruka Hiraoka, Ayaka Banno, Zheyu Meng, Mizuki Tada, Tatsuma Ishida, Pingxue Lyu, Kengo Kokubo, Hirotaka Murase, Fumitaka Hashiya, Yasuaki Kimura, Satoshi Uchida & Hiroshi Abe
- Journal Title
  
  nature communications
  
  Volume: 14 Issue: 1 Pages: 2657-2657
- DOI
  10.1038/s41467-023-38244-8
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21J15693, KAKENHI-PROJECT-21H04962
[Journal Article] Polyplex designs for improving the stability and safety of RNA therapeutics2023
- Author(s)
  Uchida Satoshi、Lau Chun Yin Jerry、Oba Makoto、Miyata Kanjiro
- Journal Title
  
  Advanced Drug Delivery Reviews
  
  Volume: 199 Pages: 114972-114972
- DOI
  10.1016/j.addr.2023.114972
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23H05451, KAKENHI-PROJECT-21H04962
[Journal Article] Block catiomers with flanking hydrolyzable tyrosinate groups enhance in vivo mRNA delivery via マ?窶苫? stacking-assisted micellar assembly2023
- Author(s)
  Wenqian Yang, Takuya Miyazaki, Yasuhiro Nakagawa, Eger Boonstra, Keita Masuda, Yuki Nakashima, Pengwen Chen, Lucas Mixich, Kevin Barthelmes, Akira Matsumoto, Peng Mi, Satoshi Uchida, Horacio Cabral
- Journal Title
  
  Science and technology of advanced materials
  
  Volume: 24 Issue: 1 Pages: 2170164-2170164
- DOI
  10.1080/14686996.2023.2170164
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04962, KAKENHI-PROJECT-21K18064, KAKENHI-PROJECT-23KJ0704, KAKENHI-PROJECT-22K19541, KAKENHI-PROJECT-21K19923, KAKENHI-PROJECT-21K18070
[Journal Article] Comb-structured mRNA vaccine tethered with short double-stranded RNA adjuvants maximizes cellular immunity for cancer treatment2023
- Author(s)
  Tockary Theofilus A.、Abbasi Saed、Matsui-Masai Miki、Hayashi Akimasa、Yoshinaga Naoto、Boonstra Eger、Wang Zheng、Fukushima Shigeto、Kataoka Kazunori、Uchida Satoshi
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 120 Issue: 29
- DOI
  10.1073/pnas.2214320120
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23H05451, KAKENHI-PROJECT-21H04962
[Journal Article] Delivery Systems of Plasmid DNA and Messenger RNA for Advanced Therapies.2022
- Author(s)
  S. Uchida
- Journal Title
  
  Pharmaceutics
  
  Volume: 14 Issue: 4 Pages: 810-810
- DOI
  10.3390/pharmaceutics14040810
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H04962, KAKENHI-PROJECT-21K19923
[Journal Article] Effective mRNA Protection by Poly(l-ornithine) Synergizes with Endosomal Escape Functionality of a Charge-Conversion Polymer toward Maximizing mRNA Introduction Efficiency2022
- Author(s)
  A. Dirisala, S. Uchida, J. Li, J.F.R. Van Guyse, K. Hayashi, S.V.C. Vummaleti, S. Kaur, Y. Mochida, S. Fukushima, K. Kataoka
- Journal Title
  
  Macromol. Rapid Commun.
  
  Volume: - Issue: 12 Pages: 2100754-2100754
- DOI
  10.1002/marc.202100754
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04962, KAKENHI-PROJECT-21K19923, KAKENHI-PROJECT-20K20209, KAKENHI-PROJECT-21K18062
[Journal Article] Microglial Immunoregulation by Apoptotic Cellular Membrane Mimetic Polymeric Particles2022
- Author(s)
  Nakagawa Yasuhiro、Lee Jeonggyu、Liu Yihua、Abbasi Saed、Hong Taehun、Cabral Horacio、Uchida Satoshi、Ebara Mitsuhiro
- Journal Title
  
  ACS Macro Letters
  
  Volume: 11 Issue: 2 Pages: 270-275
- DOI
  10.1021/acsmacrolett.1c00643
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K19045, KAKENHI-PROJECT-21H04962, KAKENHI-PROJECT-19H04476, KAKENHI-PROJECT-21K19923, KAKENHI-PROJECT-21K18064, KAKENHI-PROJECT-23K25217, KAKENHI-PUBLICLY-21H05513
[Journal Article] Complete Chemical Synthesis of Minimal Messenger RNA by Efficient Chemical Capping Reaction2022
- Author(s)
  Naoko Abe, Akihiro Imaeda, Masahito Inagaki, Zhenmin Li, Daisuke Kawaguchi, Kaoru Onda, Yuko Nakashima, Satoshi Uchida, Fumitaka Hashiya, Yasuaki Kimura, Hiroshi Abe
- Journal Title
  
  ACS Chemical Biology
  
  Volume: 17 Issue: 6 Pages: 1308-1314
- DOI
  10.1021/acschembio.1c00996
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H04962, KAKENHI-PROJECT-21K19923
[Journal Article] Cell-Penetrating Peptides: Emerging Tools for mRNA Delivery2022
- Author(s)
  H. Yokoo, M. Oba, S. Uchida
- Journal Title
  
  Pharmaceutics
  
  Volume: 14 Issue: 1 Pages: 78-78
- DOI
  10.3390/pharmaceutics14010078
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H04962, KAKENHI-PROJECT-21K19923
[Journal Article] Size-controlled bimodal in vivo nanoprobes as near-infrared phosphors and positive contrast agents for magnetic resonance imaging2021
- Author(s)
  K. Okubo, R. Takeda, S. Murayama, M. Umezawa, M. Kamimura, K. Osada, I. Aoki, K. Soga,
- Journal Title
  
  Science and Technology of Advanced Materials
  
  Volume: 22 Issue: 6 Pages: 160-172
- DOI
  10.3390/pharmaceutics13060800
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03178, KAKENHI-PROJECT-21H04962, KAKENHI-PROJECT-21K19014, KAKENHI-PROJECT-21K19923, KAKENHI-PROJECT-17KK0102, KAKENHI-PROJECT-23K21857, KAKENHI-PROJECT-20H04524
[Journal Article] mRNA loading into ATP-responsive polyplex micelles with optimal density of phenylboronate ester crosslinking to balance robustness in the biological milieu and intracellular translational efficiency2021
- Author(s)
  Yoshinaga Naoto、Uchida Satoshi、Dirisala Anjaneyulu、Naito Mitsuru、Osada Kensuke、Cabral Horacio、Kataoka Kazunori
- Journal Title
  
  Journal of Controlled Release
  
  Volume: 330 Pages: 317-328
- DOI
  10.1016/j.jconrel.2020.12.033
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17KK0102, KAKENHI-PROJECT-18H03529, KAKENHI-PROJECT-17K20086, KAKENHI-PROJECT-18K18393, KAKENHI-PROJECT-20H04524
[Journal Article] Bioinspired Silicification of mRNA-Loaded Polyion Complexes for Macrophage-Targeted mRNA Delivery2021
- Author(s)
  R. Kamegawa, M. Naito, S. Uchida, H.J. Kim, B.S. Kim, K. Miyata
- Journal Title
  
  ACS Applied Bio Materials
  
  Volume: 4 Issue: 11 Pages: 7790-7799
- DOI
  10.1021/acsabm.1c00704
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04962, KAKENHI-PROJECT-21K19923, KAKENHI-PROJECT-19J22910
[Journal Article] Treatment of ischemic neuronal death by introducing brain-derived neurotrophic factor mRNA using polyplex nanomicelle2021
- Author(s)
  Y. Fukushima, S. Uchida, H. Imai, H. Nakatomi, K. Kataoka, N. Saito, K. Itaka
- Journal Title
  
  Biomaterials
  
  Volume: 270 Pages: 120681-120681
- DOI
  10.1016/j.biomaterials.2021.120681
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H03529, KAKENHI-PROJECT-19H03776, KAKENHI-PROJECT-17K20086, KAKENHI-PROJECT-19K18381
[Journal Article] Bridging mRNA and polycation using RNA oligonucleotide derivatives improves the robustness of polyplex micelle for efficient mRNA delivery.2021
- Author(s)
  N. Yoshinaga, S. Uchida, A. Dirisala, M. Naito, K. Koji, K. Osada, H. Cabral, K. Kataoka,
- Journal Title
  
  Advanced Healthcare Materials,
  
  Volume: - Issue: 9 Pages: 2102016-2102016
- DOI
  10.1002/adhm.202102016
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03178, KAKENHI-PROJECT-21H04962, KAKENHI-PROJECT-21K19014, KAKENHI-PROJECT-21K19923, KAKENHI-PROJECT-21K18062, KAKENHI-PROJECT-17KK0102, KAKENHI-PROJECT-23K21857, KAKENHI-PROJECT-20H04524
[Journal Article] A proton/macromolecule-sensing approach distinguishes changes in biological membrane permeability during polymer/lipid-based nucleic acid delivery2021
- Author(s)
  Boonstra Eger、Hatano Hiroaki、Miyahara Yuji、Uchida Satoshi、Goda Tatsuro、Cabral Horacio
- Journal Title
  
  Journal of Materials Chemistry B
  
  Volume: 9 Issue: 21 Pages: 4298-4302
- DOI
  10.1039/d1tb00645b
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K12776, KAKENHI-PROJECT-21H04962, KAKENHI-PROJECT-21K19923, KAKENHI-PROJECT-20H04524
[Journal Article] A helix foldamer oligopeptide improves intracellular stability and prolongs protein expression of the delivered mRNA2021
- Author(s)
  S. Uchida, Y. Yamaberi, M. Tanaka, M. Oba
- Journal Title
  
  Nanoscale
  
  Volume: 13 Issue: 45 Pages: 18941-18946
- DOI
  10.1039/d1nr03600a
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H04962, KAKENHI-PROJECT-21K19923
[Journal Article] Multifunctional Immunoadjuvants for Use in Minimalist Nucleic Acid Vaccines2021
- Author(s)
  S. Abbasi, S. Uchida
- Journal Title
  
  Pharmaceutics
  
  Volume: 13 Issue: 5 Pages: 644-644
- DOI
  10.3390/pharmaceutics13050644
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H04962, KAKENHI-PROJECT-21K19923
[Journal Article] Co-encapsulation of Cas9 mRNA and guide RNA in polyplex micelles enables genome editing in mouse brain2021
- Author(s)
  S. Abbasi, S. Uchida, K. Toh, T.A. Tockary, A. Dirisala, K. Hayashi, S. Fukushima, K. Kataoka
- Journal Title
  
  J. Control. Release
  
  Volume: 332 Pages: 260-268
- DOI
  10.1016/j.jconrel.2021.02.026
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03529, KAKENHI-PROJECT-19F19116, KAKENHI-PROJECT-17K20086, KAKENHI-PROJECT-18K18393
[Journal Article] Enzymatically Transformable Polymersome-Based Nanotherapeutics to Eliminate Minimal Relapsable Cancer2021
- Author(s)
  J. Li, Z. Ge, K. Toh, X. Liu, A. Dirisala, W. Ke, P. Wen, H. Zhou, Z. Wang, S. Xiao, J.F.R. Van Guyse, T.A. Tockary, J. Xie, D. Gonzalez-Carter, H. Kinoh, S. Uchida, Y. Anraku, K. Kataoka
- Journal Title
  
  Adv. Mater.
  
  Volume: 33 Issue: 49 Pages: 2105254-2105254
- DOI
  10.1002/adma.202105254
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04962, KAKENHI-PROJECT-21K19923, KAKENHI-PROJECT-20K20209, KAKENHI-PROJECT-21K18062
[Journal Article] Nanomedicine-Based Approaches for mRNA Delivery2020
- Author(s)
  S. Uchida, F. Perche, C. Pichon, H. Cabral
- Journal Title
  
  Mol. Pharm._
  
  Volume: 17 Issue: 10 Pages: 3654-3684
- DOI
  10.1021/acs.molpharmaceut.0c00618
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03529, KAKENHI-PROJECT-17K20086, KAKENHI-PROJECT-20H04524
[Journal Article] mRNA as a Tool for Gene Transfection in 3D Cell Culture for Future Regenerative Therapy2020
- Author(s)
  S. Uchida, K. Yanagihara, A. Matsui, K. Kataoka, K. Itaka
- Journal Title
  
  Micromachines
  
  Volume: 11 Issue: 4 Pages: 426-426
- DOI
  10.3390/mi11040426
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H03529, KAKENHI-PROJECT-19H03776, KAKENHI-PROJECT-17K20086
[Journal Article] Transient stealth coating of liver sinusoidal wall by anchoring two-armed PEG for retargeting nanomedicines2020
- Author(s)
  Dirisala Anjaneyulu、Uchida Satoshi、Toh Kazuko、Li Junjie、Osawa Shigehito、Tockary Theofilus A.、Liu Xueying、Abbasi Saed、Hayashi Kotaro、Mochida Yuki、Fukushima Shigeto、Kinoh Hiroaki、Osada Kensuke、Kataoka Kazunori
- Journal Title
  
  Science Advances
  
  Volume: 6 Issue: 26
- DOI
  10.1126/sciadv.abb8133
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17KK0102, KAKENHI-PROJECT-18H03529, KAKENHI-PROJECT-19F19116, KAKENHI-PROJECT-17K20086, KAKENHI-PROJECT-18K18393
[Journal Article] Bundling of mRNA strands inside polyion complexes improves mRNA delivery efficiency in vitro and in vivo2020
- Author(s)
  Koji Kyoko、Yoshinaga Naoto、Mochida Yuki、Hong Taehun、Miyazaki Takuya、Kataoka Kazunori、Osada Kensuke、Cabral Horacio、Uchida Satoshi
- Journal Title
  
  Biomaterials
  
  Volume: 261 Pages: 120332-120332
- DOI
  10.1016/j.biomaterials.2020.120332
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17KK0102, KAKENHI-PROJECT-18H03529, KAKENHI-PROJECT-17K20086, KAKENHI-PROJECT-19K23614, KAKENHI-PROJECT-20H04524
[Journal Article] Polymeric Nanocarriers with Controlled Chain Flexibility Boost mRNA Delivery In Vivo through Enhanced Structural Fastening2020
- Author(s)
  Miyazaki Takuya、Uchida Satoshi、Nagatoishi Satoru、Koji Kyoko、Hong Taehun、Fukushima Shigeto、Tsumoto Kouhei、Ishihara Kazuhiko、Kataoka Kazunori、Cabral Horacio
- Journal Title
  
  Advanced Healthcare Materials
  
  Volume: 9 Issue: 16 Pages: 2000538-2000538
- DOI
  10.1002/adhm.202000538
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02082, KAKENHI-PROJECT-18H03529, KAKENHI-PROJECT-20H02531, KAKENHI-PROJECT-17K20086, KAKENHI-PROJECT-20H04524
[Journal Article] A 50-nm-Sized Micellar Assembly of Thermoresponsive Polymer-Antisense Oligonucleotide Conjugates for Enhanced Gene Knockdown in Lung Cancer by Intratracheal Administration.2020
- Author(s)
  B. S. Kim, S. Osawa, M. Naito, S. Ogura, R. Kamegawa, H. Ishida, H. J. Kim, S. Uchida, K. Miyata
- Journal Title
  
  Advanced Therapeutics
  
  Volume: 3 Issue: 2 Pages: 1900123-1900123
- DOI
  10.1002/adtp.201900123
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K20086, KAKENHI-PROJECT-18H03529
[Journal Article] Guanidine-phosphate interactions stabilize polyion complex micelles based on flexible catiomers to improve mRNA delivery2020
- Author(s)
  T. Miyazaki, S. Uchida, H. Hatano, Y. Miyahara, A. Matsumoto, H. Cabral
- Journal Title
  
  Eur. Polym. J.
  
  Volume: 140 Pages: 110028-110028
- DOI
  10.1016/j.eurpolymj.2020.110028
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03529, KAKENHI-PROJECT-17K20086, KAKENHI-PROJECT-19K23614, KAKENHI-PROJECT-20H04529, KAKENHI-PROJECT-20H04524
[Journal Article] A chemically unmodified agonistic DNA with growth factor functionality for in vivo therapeutic application2020
- Author(s)
  Ueki Ryosuke、Uchida Satoshi、Kanda Naoto、Yamada Naoki、Ueki Ayaka、Akiyama Momoko、Toh Kazuko、Cabral Horacio、Sando Shinsuke
- Journal Title
  
  Science Advances
  
  Volume: 6 Issue: 14
- DOI
  10.1126/sciadv.aay2801
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K20693, KAKENHI-PROJECT-18J01989, KAKENHI-PROJECT-18H03529, KAKENHI-PROJECT-17K20086
[Journal Article] Bundling mRNA strands to prepare nano-assemblies with enhanced stability towards RNase for in vivo delivery.2019
- Author(s)
  N. Yoshinaga, E. Cho, K. Koji, Y. Mochida, M. Naito, K. Osada, K. Kataoka, H. Cabral, S. Uchida
- Journal Title
  
  Angew. Chem. Int. Ed.
  
  Volume: 58 Issue: 33 Pages: 11360-11363
- DOI
  10.1002/anie.201905203
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K20086, KAKENHI-PROJECT-17KK0102, KAKENHI-PROJECT-16H03178, KAKENHI-PROJECT-16H03179, KAKENHI-PROJECT-18H03529, KAKENHI-PROJECT-18K19901
[Journal Article] PEG-OligoRNA Hybridization of mRNA for Developing Sterically Stable Lipid Nanoparticles toward In Vivo Administration2019
- Author(s)
  Kurimoto Shota、Yoshinaga Naoto、Igarashi Kazunori、Matsumoto Yu、Cabral Horacio、Uchida Satoshi
- Journal Title
  
  Molecules
  
  Volume: 24 Issue: 7 Pages: 1303-1303
- DOI
  10.3390/molecules24071303
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03179, KAKENHI-PROJECT-17K20086, KAKENHI-PROJECT-18H03529, KAKENHI-PROJECT-18K19901
[Journal Article] In vivo rendezvous of small nucleic acid drugs with charge-matched block catiomers to target cancers2019
- Author(s)
  Watanabe Sumiyo、Hayashi Kotaro、Toh Kazuko、Kim Hyun Jin、Liu Xueying、Chaya Hiroyuki、Fukushima Shigeto、Katsushima Keisuke、Kondo Yutaka、Uchida Satoshi、Ogura Satomi、Nomoto Takahiro、et al.
- Journal Title
  
  Nature Communications
  
  Volume: 10 Issue: 1 Pages: 1894-1894
- DOI
  10.1038/s41467-019-09856-w
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K18383, KAKENHI-PROJECT-17KT0048, KAKENHI-PROJECT-19K12799, KAKENHI-PROJECT-17K20086, KAKENHI-PROJECT-18K18391, KAKENHI-PROJECT-17KK0102, KAKENHI-PROJECT-18H04163, KAKENHI-PROJECT-16H03178, KAKENHI-PROJECT-17H03582, KAKENHI-PROJECT-18H02797, KAKENHI-PROJECT-18H03529, KAKENHI-PROJECT-17H04743, KAKENHI-PROJECT-17K07234, KAKENHI-PROJECT-17H02098
[Journal Article] Single-stranded DNA-packaged polyplex micelle as adeno-associated-virus-inspired compact vector to systemically target stroma-rich pancreatic cancer.2019
- Author(s)
  T. A. Tockary, W. Foo, A. Dirisala, Q. Chen, S. Uchida, S. Osawa, Y. Mochida, X. Liu, H. Kinoh, H. Cabral, K. Osada, K. Kataoka
- Journal Title
  
  ACS Nano
  
  Volume: 13 Issue: 11 Pages: 12732-12742
- DOI
  10.1021/acsnano.9b04676
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K20086, KAKENHI-PROJECT-18K18393, KAKENHI-PROJECT-17KK0102, KAKENHI-PROJECT-16H03178, KAKENHI-PROJECT-16H03179, KAKENHI-PROJECT-18H03529, KAKENHI-PROJECT-17K07234, KAKENHI-PROJECT-18K19901
[Journal Article] Tunable non-enzymatic degradability of N-substituted polyaspartamide main chain by amine protonation and alkyl spacer length in side chains for enhanced messenger RNA transfection efficiency.2019
- Author(s)
  M. Naito, Y. Otsu, R. Kamegawa, K. Hayashi, S. Uchida, H. -J. Kim, K. Miyata
- Journal Title
  
  Sci. Technol. Adv. Mater.
  
  Volume: 20 Issue: 1 Pages: 105-115
- DOI
  10.1080/14686996.2019.1569818
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K20086, KAKENHI-PROJECT-18H03529, KAKENHI-PROJECT-18K18379
[Journal Article] Induced packaging of mRNA into polyplex micelles by regulated hybridization with a small number of cholesteryl RNA oligonucleotides directed enhanced in vivo transfection.2019
- Author(s)
  N. Yoshinaga, S. Uchida, M. Naito, K. Osada, H. Cabral, K. Kataoka
- Journal Title
  
  Biomaterials
  
  Volume: 197 Pages: 255-267
- DOI
  10.1016/j.biomaterials.2019.01.023
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K20086, KAKENHI-PROJECT-17KK0102, KAKENHI-PROJECT-16H03178, KAKENHI-PROJECT-16H03179, KAKENHI-PROJECT-18H03529, KAKENHI-PROJECT-18K19901, KAKENHI-PROJECT-20K20386, KAKENHI-PROJECT-18J14336, KAKENHI-PROJECT-18K18379
[Journal Article] Treatment of intervertebral disk disease by administration of messenger RNA encoding a cartilage-anabolic transcription factor.2019
- Author(s)
  C. -Y. Lin, S. T. Crowley, S. Uchida, Y. Komaki, K. Kataoka, K. Itaka
- Journal Title
  
  Mol. Ther. Nucleic Acids
  
  Volume: 16 Pages: 162-171
- DOI
  10.1016/j.omtn.2019.02.012
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K20086, KAKENHI-PROJECT-15H03017, KAKENHI-PROJECT-18H03529, KAKENHI-PROJECT-17F17410, KAKENHI-PROJECT-16K10842, KAKENHI-PROJECT-19H03776, KAKENHI-PROJECT-20K20386
[Journal Article] Precise tuning of disulfide crosslinking in mRNA polyplex micelles for optimizing extracellular and intracellular nuclease tolerability.2019
- Author(s)
  A. Dirisala, S. Uchida, T. A. Tockary, N. Yoshinaga, J. Li, S. Osawa, L. Gorantla, S. Fukushima, K. Osada, K. Kataoka
- Journal Title
  
  J. Drug Target.
  
  Volume: 印刷中 Issue: 5-6 Pages: 670-680
- DOI
  10.1080/1061186x.2018.1550646
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K20086, KAKENHI-PROJECT-17KK0102, KAKENHI-PROJECT-16H03178, KAKENHI-PROJECT-18H03529, KAKENHI-PROJECT-18K18393
[Journal Article] Design concepts of polyplex micelles for in vivo therapeutic delivery of plasmid DNA and messenger RNA.2019
- Author(s)
  S. Uchida, K. Kataoka
- Journal Title
  
  J. Biomed. Mater. Res. A
  
  Volume: 107 Issue: 5 Pages: 978-990
- DOI
  10.1002/jbm.a.36614
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K20086, KAKENHI-PROJECT-18H03529, KAKENHI-PROJECT-20K20386
[Journal Article] Enhancement of motor function 1 recovery after spinal cord injury in mice by delivery of brain derived neurotrophic factor mRNA.2019
- Author(s)
  S. T. Crowley, Y. Fukushima, S. Uchida, K. Kataoka, K. Itaka
- Journal Title
  
  Mol. Ther. Nucleic Acids
  
  Volume: 17 Pages: 465-476
- DOI
  10.1016/j.omtn.2019.06.016
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K20086, KAKENHI-PROJECT-19K18381, KAKENHI-PROJECT-18H03529, KAKENHI-PROJECT-17F17410, KAKENHI-PROJECT-19H03776
[Journal Article] Prolonged engraftment of transplanted hepatocytes in the liver by transient pro-survival factor supplementation using ex vivo mRNA transfection.2018
- Author(s)
  A. Matsui, S. Uchida, A. Hayashi, K. Kataoka, K. Itaka
- Journal Title
  
  J. Control. Release
  
  Volume: 285 Pages: 1-11
- DOI
  10.1016/j.jconrel.2018.06.033
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K20086, KAKENHI-PROJECT-18H03529, KAKENHI-PROJECT-15H03017
[Journal Article] Designing immunostimulatory double stranded messenger RNA with maintained translational activity through hybridization with poly A sequences for effective vaccination2018
- Author(s)
  Uchida Satoshi、Yoshinaga Naoto、Yanagihara Kayoko、Yuba Eiji、Kataoka Kazunori、Itaka Keiji
- Journal Title
  
  Biomaterials
  
  Volume: 150 Pages: 162-170
- DOI
  10.1016/j.biomaterials.2017.09.033
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K20086, KAKENHI-PROJECT-15H03024, KAKENHI-PROJECT-15K20962, KAKENHI-PROJECT-25000006
[Journal Article] Treatment of Bone Defects by Transplantation of Genetically Modified Mesenchymal Stem Cell Spheroids2018
- Author(s)
  Yanagihara K, Uchida S, Ohba S, Kataoka K, Itaka K
- Journal Title
  
  Molecular Therapy - Methods & Clinical Development
  
  Volume: 9 Pages: 358-366
- DOI
  10.1016/j.omtm.2018.04.006
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K15642, KAKENHI-PROJECT-17K20086, KAKENHI-PROJECT-18K19635
[Journal Article] Systemic Delivery of Folate-PEG siRNA Lipopolyplexes with Enhanced Intracellular Stability for In Vivo Gene Silencing in Leukemia2017
- Author(s)
  Lee Dian-Jang、Kessel Eva、Lehto Taavi、Liu Xueying、Yoshinaga Naoto、Padari K?rt、Chen Ying-Chen、Kempter Susanne、Uchida Satoshi、R?dler Joachim O.、Pooga Margus、Sheu Ming-Thau、Kataoka Kazunori、Wagner Ernst
- Journal Title
  
  Bioconjugate chemistry
  
  Volume: 28 Issue: 9 Pages: 2393-2409
- DOI
  10.1021/acs.bioconjchem.7b00383
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K20086, KAKENHI-PROJECT-15K20962, KAKENHI-PROJECT-25000006
[Journal Article] Improved brain expression of anti-amyloid β scFv by complexation of mRNA including a secretion sequence with PEG-based block catiomer.2017
- Author(s)
  F. Perche, S. Uchida, H. Akiba, C.-Y. Lin, M. Ikegami, A. Disrala, T. Nakashima, K. Itaka, K. Tsumoto, K. Kataoka
- Journal Title
  
  Curr. Alzheimer Res.
  
  Volume: 14 Issue: 3 Pages: 295-302
- DOI
  10.2174/1567205013666161108110031
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K20962, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-16H02420
[Journal Article] Polyplex Micelles with Phenylboronate/Gluconamide Cross-Linking in the Core Exerting Promoted Gene Transfection through Spatiotemporal Responsivity to Intracellular pH and ATP Concentration2017
- Author(s)
  Yoshinaga Naoto、Ishii Takehiko、Naito Mitsuru、Endo Taisuke、Uchida Satoshi、Cabral Horacio、Osada Kensuke、Kataoka Kazunori
- Journal Title
  
  Journal of the American Chemical Society
  
  Volume: 139 Issue: 51 Pages: 18567-18575
- DOI
  10.1021/jacs.7b08816
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K20086, KAKENHI-PROJECT-16H03178, KAKENHI-PROJECT-16H03179, KAKENHI-PROJECT-15K20962, KAKENHI-PROJECT-25000006
[Journal Article] Glycaemic control boosts glucosylated nanocarrier crossing the BBB into the brain2017
- Author(s)
  Anraku Y.、Kuwahara H.、Fukusato Y.、Mizoguchi A.、Ishii T.、Nitta K.、Matsumoto Y.、Toh K.、Miyata K.、Uchida S.、Nishina K.、Osada K.、Itaka K.、Nishiyama N.、Mizusawa H.、Yamasoba T.、Yokota T.、Kataoka K.
- Journal Title
  
  Nat Commun
  
  Volume: 8 Issue: 1 Pages: 2001-2009
- DOI
  10.1038/s41467-017-00952-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17KT0048, KAKENHI-PROJECT-16K11226, KAKENHI-PROJECT-17K20086, KAKENHI-PROJECT-15H04635, KAKENHI-PROJECT-15H04813, KAKENHI-PROJECT-16H03178, KAKENHI-PROJECT-17H04742, KAKENHI-PROJECT-16F16058, KAKENHI-PROJECT-16F16407, KAKENHI-PROJECT-16K15104, KAKENHI-PROJECT-15K20962, KAKENHI-PROJECT-25000006
[Journal Article] Synthetic polyamines to regulate mRNA translation through the preservative binding of eukaryotic initiation factor 4E to the cap structure.2016
- Author(s)
  H. Uchida, K. Itaka, S. Uchida, T. Ishii, T. Suma, K. Miyata, M. Oba, N. Nishiyama, K. Kataoka
- Journal Title
  
  J. Am. Chem. Soc.
  
  Volume: 138 Issue: 5 Pages: 1478-1481
- DOI
  10.1021/jacs.5b11726
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K20962, KAKENHI-PROJECT-15H03017, KAKENHI-PROJECT-25000006
[Journal Article] Screening of mRNA chemical modification to maximize protein expression with reduced immunogenicity.2016
- Author(s)
  S. Uchida, K. Kataoka, K. Itaka
- Journal Title
  
  Pharmaceutics
  
  Volume: 7 Issue: 3 Pages: 137-151
- DOI
  10.3390/pharmaceutics7030137
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K20962, KAKENHI-PROJECT-15H03017, KAKENHI-PROJECT-25000006
[Journal Article] Treatment of spinal cord injury by an advanced cell transplantation technology using brain-derived neurotrophic factor-transfected mesenchymal stem cell spheroids2016
- Author(s)
  Uchida S, Hayakawa K, Ogata T, Tanaka S, Kataoka K, Itaka K
- Journal Title
  
  Biomaterials
  
  Volume: 109 Pages: 1-11
- DOI
  10.1016/j.biomaterials.2016.09.007
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H03017, KAKENHI-PROJECT-15K20962
[Journal Article] Systemic delivery of messenger RNA for the treatment of pancreatic cancer using polyplex nanomicelles with a cholesterol moiety.2016
- Author(s)
  S. Uchida, H. Kinoh, T. Ishii, A. Matsui, T. A. Tockary, K. M. Takeda, H. Uchida, K. Osada, K. Itaka, K. Kataoka
- Journal Title
  
  Biomaterials
  
  Volume: 82 Pages: 221-228
- DOI
  10.1016/j.biomaterials.2015.12.031
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K20962, KAKENHI-PROJECT-15H03017, KAKENHI-PROJECT-14J11005, KAKENHI-PROJECT-25000006
[Journal Article] Messenger RNA delivery of a cartilage-anabolic transcription factor as a disease-modifying strategy for osteoarthritis treatment.2016
- Author(s)
  1.Aini H, Itaka K, Fujisawa A, Uchida H, Uchida S, Fukushima S, Kataoka K, Saito T, Chung UI, Ohba S.
- Journal Title
  
  Sci Rep.
  
  Volume: 6 Issue: 1 Pages: 18743-18743
- DOI
  10.1038/srep18743
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462285, KAKENHI-PROJECT-26670859, KAKENHI-PROJECT-15K20962, KAKENHI-PROJECT-15H03017, KAKENHI-PROJECT-25293316, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-25253087, KAKENHI-PROJECT-15K15535, KAKENHI-PROJECT-26293330
[Journal Article] Polyplex micelle installing intracellular self-processing functionalities without free catiomers for safe and efficient systemic gene therapy through tumor vasculature targeting2016
- Author(s)
  Q. Chen, K. Osada, Z. Ge, S. Uchida, T. A. Tockary, A. Dirisala, A. Matsui, K. Toh, K. M. Takeda, X. Liu, T. Nomoto, T. Ishii, M. Oba, Y. Matsumoto, K. Kataoka
- Journal Title
  
  Biomaterials
  
  Volume: 113 Pages: 253-265
- DOI
  10.1016/j.biomaterials.2016.10.042
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-14J11005, KAKENHI-PROJECT-15K20962, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-17KT0048, KAKENHI-PROJECT-16K11226, KAKENHI-PROJECT-16H03178
[Journal Article] Messenger RNA-based therapeutics for brain diseases: An animal study for augmenting clearance of beta-amyloid by intracerebral administration of neprilysin mRNA loaded in polyplex nanomicelles2016
- Author(s)
  Lin CY, Perche F, Ikegami M, Uchida S, Kataoka K, Itaka K
- Journal Title
  
  J Control Release
  
  Volume: 235 Pages: 268-275
- DOI
  10.1016/j.jconrel.2016.06.001
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H03017, KAKENHI-PROJECT-14F04406, KAKENHI-PROJECT-15K20962, KAKENHI-PROJECT-25000006
[Journal Article] Gene transfection toward spheroid cells on micropatterned culture plates for genetically-modified cell transplantation.2015
- Author(s)
  K. Itaka, S. Uchida, A. Matsui, K. Yanagihara, M. Ikegami, T. Endo, T. Ishii, K. Kataoka
- Journal Title
  
  Journal of Visualized Experiments
  
  Volume: 101 Issue: 101
- DOI
  10.3791/52384
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K20962
[Journal Article] Development of biodegradable polycation-based inhalable dry gene powders by spray freeze drying.2015
- Author(s)
  T. Okuda, Y. Suzuki, Y. Kobayashi, T. Ishii, S. Uchida, K. Itaka, K. Kataoka, H. Okamoto
- Journal Title
  
  Pharmaceutics
  
  Volume: 7 Issue: 3 Pages: 233-254
- DOI
  10.3390/pharmaceutics7030233
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K20962
[Journal Article] Toroidal packaging of pDNA into block ionomer micelles exerting promoted in vivo gene expression.2015
- Author(s)
  Y. Li, K. Osada, Q. Chen, T. A. Tockary, A. Dirisala, K. M. Takeda, S. Uchida, K. Nagata, K. Itaka, K. Kataoka
- Journal Title
  
  Biomacromolecules
  
  Volume: 16 Issue: 9 Pages: 2664-2671
- DOI
  10.1021/acs.biomac.5b00491
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K20962, KAKENHI-PROJECT-14J11005, KAKENHI-PROJECT-25000006
[Journal Article] Regulated protonation of polyaspartamide derivatives bearing repeated aminoethylene side chains for efficient intracellular siRNA delivery with minimal cytotoxicity2015
- Author(s)
  H. Gao, H. Takemoto, Q. Chen, M. Naito, H. Uchida, X. Liu, K. Miyata, K. Kataoka
- Journal Title
  
  Chemical Communications
  
  Volume: 51 Issue: 15 Pages: 3158-3161
- DOI
  10.1039/c4cc09859e
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-15K16331
[Journal Article] Messenger RNA-based therapeutics for the treatment of apoptosis-associated diseases.2015
- Author(s)
  A. Matsui, S. Uchida, T. Ishii, K. Itaka, K. Kataoka
- Journal Title
  
  Scientific Reports
  
  Volume: 5 Issue: 1 Pages: 15810-15810
- DOI
  10.1038/srep15810
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K20962, KAKENHI-PROJECT-15H03017, KAKENHI-PROJECT-25000006
[Journal Article] A tadpole-shaped gene carrier with distinct phase segregation in a ternary polymeric micelle2015
- Author(s)
  Chen Q, Osada K, Pennisi M, Uchida S, Tockary TA, Dirisala A, Li Y, Takeda KM, Oniyanagi S, Itaka K, Kataoka K
- Journal Title
  
  Soft Matter
  
  Volume: 11 Issue: 14 Pages: 2718-2722
- DOI
  10.1039/c4sm02850c
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-14J11005, KAKENHI-PROJECT-24300170, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-25882011
[Journal Article] Intrathecal injection of a therapeutic gene-containing polyplex to treat spinal cord injury.2015
- Author(s)
  Hayakawa K, Uchida S, Ogata T, Tanaka S, Kataoka K, Itaka K.
- Journal Title
  
  J Control Release
  
  Volume: 197 Pages: 1-9
- DOI
  10.1016/j.jconrel.2014.10.027
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24300170, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-25882011
[Journal Article] Optimized rod length of polyplex micelles for maximizing transfection efficiency and their performance in systemic gene therapy against stroma-rich pancreatic tumors2014
- Author(s)
  Dirisala A, Osada K, Chen Q, Tockary TA, Machitani K, Osawa S, Liu X, Ishii T, Miyata K, Oba M, Uchida S, Itaka K, Kataoka K
- Journal Title
  
  Biomaterials
  
  Volume: 35(20) Issue: 20 Pages: 5359-5368
- DOI
  10.1016/j.biomaterials.2014.03.037
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-14J11005, KAKENHI-PROJECT-24300170, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-25882011
[Journal Article] Muscle-targeted hydrodynamic gene introduction of insulin-like growth factor-1 using polyplex nanomicelle to treat peripheral nerve injury.2014
- Author(s)
  Nagata K, Itaka K, Baba M, Uchida S, Ishii T, Kataoka K.
- Journal Title
  
  J Control Release
  
  Volume: 183C Pages: 27-34
- DOI
  10.1016/j.jconrel.2014.03.021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24300170, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-25882011
[Journal Article] An injectable spheroid system with genetic modification for cell transplantation therapy2014
- Author(s)
  Uchida S, ltaka K, Nomoto T, Endo T, Matsumoto Y, Ishii T, Kataoka K
- Journal Title
  
  Biomaterials
  
  Volume: 35(8) Issue: 8 Pages: 2499-506
- DOI
  10.1016/j.biomaterials.2013.12.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659708, KAKENHI-PROJECT-23790043, KAKENHI-PROJECT-25882011, KAKENHI-PROJECT-26670738
[Journal Article] Modulated protonation of side chain aminoethylene repeats in N-substituted polyaspartamides promotes mRNA transfection2014
- Author(s)
  H. Uchida, K. Itaka, T. Nomoto, T. ishii, T. Suma, M. Ikegami, K. Miyata, M. Oba, N. Nishiyama, K. Kataoka
- Journal Title
  
  J. Am. Chem. Soc.
  
  Volume: 136 Issue: 35 Pages: 12396-12405
- DOI
  10.1021/ja506194z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390009, KAKENHI-PROJECT-24300170, KAKENHI-PROJECT-25000006
[Journal Article] Targeted gene delivery by polyplex micelles with crowded PEG palisade and cRGD moiety for systemic treatment of pancreatic tumors2014
- Author(s)
  Z. Ge, Q. Chen, K. Osada, X. Liu, T. A. Tockary, S. Uchida, A. Dirisala, T. Ishii, T. Nomoto, K. Toh, Y. Matsumoto, M. Oba, M. R. Kano, K. Itaka, K. Kataoka
- Journal Title
  
  Biomaterials
  
  Volume: 35 Issue: 10 Pages: 3416-3426
- DOI
  10.1016/j.biomaterials.2013.12.086
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790043, KAKENHI-PROJECT-23790433, KAKENHI-PROJECT-24300170, KAKENHI-PROJECT-24790530, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-25882011, KAKENHI-PROJECT-26293119, KAKENHI-PROJECT-26670738
[Journal Article] Tethered PEG Crowdedness Determining Shape and Blood Circulation Profile of Polyplex Micelle Gene Carriers2013
- Author(s)
  Theofilus A. Tockary, Kensuke Osada, Qixian Chen, Kaori Machitani, Anjaneyulu Dirisala, Satoshi Uchida, Takahiro Nomoto, Kazuko Toh, Yu Matsumoto, Keiji Itaka, Koji Nitta, Kuniaki Nagayama, and Kazunori Kataoka
- Journal Title
  
  Macromolecules
  
  Volume: 46 Issue: 16 Pages: 6585-6592
- DOI
  10.1021/ma401093z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24300170, KAKENHI-PROJECT-24790530, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-25882011
[Patent] 経皮投与用のＲＮＡを含む組成物および当該組成物の投与方法2023
- Inventor(s)
  内田智士，他4名
- Industrial Property Rights Holder
  内田智士，他4名
- Industrial Property Rights Type
  特許
- Filing Date
  2023
- Overseas
- Data Source
  KAKENHI-PROJECT-21H04962
[Patent] ｍＲＮＡワクチン2022
- Inventor(s)
  内田智士, 鈴木美紀
- Industrial Property Rights Holder
  内田智士, 鈴木美紀
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2022-198116
- Filing Date
  2022
- Data Source
  KAKENHI-PROJECT-21H04962
[Patent] 経皮投与用のＲＮＡを含む組成物および当該組成物の投与方法2022
- Inventor(s)
  内田智士，他
- Industrial Property Rights Holder
  川崎市産業振興財団，他
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2022-009172
- Filing Date
  2022
- Data Source
  KAKENHI-PROJECT-21H04962
[Patent] ゲノム編集用ミセル2020
- Inventor(s)
  片岡一則，内田智士，アッバシサエド
- Industrial Property Rights Holder
  片岡一則，内田智士，アッバシサエド
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2020-113434
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-17K20086
[Patent] ゲノム編集用ミセル2020
- Inventor(s)
  1.片岡一則，内田智士，アッバシサエド
- Industrial Property Rights Holder
  川崎市産業振興財団
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2020-113434
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-18H03529
[Patent] mRNA送達用キャリアおよびこれを含む組成物2019
- Inventor(s)
  片岡一則，内田智士，アンジャネユルディリサラ
- Industrial Property Rights Holder
  川崎市産業振興財団
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Overseas
- Data Source
  KAKENHI-PROJECT-18H03529
[Patent] 体内における薬物動態を制御する組成物2018
- Inventor(s)
  ディリサラアンジャネユル、大澤重仁、藤加珠子、内田智士、片岡一則、林光太朗
- Industrial Property Rights Holder
  公益財団法人川崎市産業振興財団
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2018-043880
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-25000006
[Patent] ｍＲＮＡの機能化方法2017
- Inventor(s)
  内田智士、吉永直人、位髙啓史、片岡一則
- Industrial Property Rights Holder
  東京大学、川崎市産業振興財団
- Industrial Property Rights Type
  特許
- Filing Date
  2017
- Overseas
- Data Source
  KAKENHI-PROJECT-15K20962
[Patent] 体内における薬物動態を制御する組成物2017
- Inventor(s)
  片岡一則、大澤重仁、内田智士、林光太郎、藤加珠子、ディリサラ
- Industrial Property Rights Holder
  川崎市産業振興財団
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2017-195061
- Filing Date
  2017
- Data Source
  KAKENHI-PROJECT-15K20962
[Patent] 血中におけるRNAの安定性の改善剤および投与方法2017
- Inventor(s)
  片岡一則、大澤重仁、林光太郎、内田智士、長田健介
- Industrial Property Rights Holder
  川崎市産業振興財団
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2017-104975
- Filing Date
  2017
- Data Source
  KAKENHI-PROJECT-15K20962
[Patent] 血中におけるRNAの安定性の改善剤および投与方法2017
- Inventor(s)
  大澤重仁、長田健介、内田智士、片岡一則、林光太朗
- Industrial Property Rights Holder
  公益財団法人川崎市産業振興財団
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2017-104975
- Filing Date
  2017
- Data Source
  KAKENHI-PROJECT-25000006
[Patent] METHOD FOR STABILIZING MRNA2017
- Inventor(s)
  内田智士、吉永直人、趙オル
- Industrial Property Rights Holder
  東京大学、川崎市産業振興財団
- Industrial Property Rights Type
  特許
- Filing Date
  2017
- Overseas
- Data Source
  KAKENHI-PROJECT-15K20962
[Patent] mRNA輸送担体の安定化方法2016
- Inventor(s)
  内田智士、片岡一則、吉永直人、位高啓史
- Industrial Property Rights Holder
  国立大学法人東京大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2016-252488
- Filing Date
  2016-12-27
- Data Source
  KAKENHI-PROJECT-25000006
[Patent] ｍＲＮＡ輸送担体の安定化方法2016
- Inventor(s)
  内田智士，片岡一則，吉永直人，位高啓史
- Industrial Property Rights Holder
  東京大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2016-252488
- Filing Date
  2016-12-27
- Data Source
  KAKENHI-PROJECT-15K20962
[Patent] ｍＲＮＡワクチン2016
- Inventor(s)
  内田智士，位高啓史，片岡一則
- Industrial Property Rights Holder
  東京大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2016-252487
- Filing Date
  2016-12-27
- Data Source
  KAKENHI-PROJECT-15K20962
[Patent] ｍＲＮＡ送達用組成物2014
- Inventor(s)
  片岡一則、位高啓史、石井武彦、内田寛邦、内田智士、馬場美雪
- Industrial Property Rights Holder
  一般社団法人医療産業イノベーション機構
- Industrial Property Rights Type
  特許
- Filing Date
  2014-02-12
- Overseas
- Data Source
  KAKENHI-PROJECT-25882011
[Patent] タンパク質発現を向上させる方法およびタンパク質発現用組成物2014
- Inventor(s)
  位髙啓史, 片岡一則, 池上賢, 内田智士, 他2名
- Industrial Property Rights Holder
  一般社団法人医療産業イノベーション機構
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2014-090634
- Filing Date
  2014-04-24
- Data Source
  KAKENHI-PROJECT-25882011
[Patent] タンパク質発現を向上させる方法およびタンパク質発現用組成物2014
- Inventor(s)
  位髙啓史, 片岡一則, 池上賢, 内田智士, 内田寛邦, 長田和也
- Industrial Property Rights Holder
  一般社団法人医療産業イノベーション機構
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2014-090634
- Filing Date
  2014-04-24
- Data Source
  KAKENHI-PROJECT-25000006
[Patent] mRNA送達用組成物2014
- Inventor(s)
  片岡一則、位高啓史、石井武彦、内田寛邦、内田智士、馬場美雪
- Industrial Property Rights Holder
  一般社団法人医療産業イノベーション機構
- Filing Date
  2014-02-12
- Overseas
- Data Source
  KAKENHI-PROJECT-25000006
[Presentation] mRNAワクチン、医薬品の基盤技術開発と医療応用2023
- Author(s)
  内田智士
- Organizer
  第72回高分子学会年次大会
- Invited
- Data Source
  KAKENHI-PROJECT-23H05451
[Presentation] mRNA vaccine development for infectious disease prevention and cancer treatment2023
- Author(s)
  内田智士
- Organizer
  The 18th international Symposium of the institute Network for Biomedical Science
- Invited
- Data Source
  KAKENHI-PROJECT-21H04962
[Presentation] 今さら聞けないmRNAワクチンの基礎2023
- Author(s)
  内田智士
- Organizer
  第97回日本感染症学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-21H04962
[Presentation] mRNA単体のジェットインジェクションによるCOVID-19ワクチン2023
- Author(s)
  内田智士、Saed Abbasi、正井三貴、林玲匡、Theofilus Tockary、秋永士朗、片岡一則
- Organizer
  第39回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-23H05451
[Presentation] Naked mRNA Jet Injection into the Skin Enables the Robust Vaccination against SARS-CoV-2 in Mice and Cynomolgus Monkeys2023
- Author(s)
  Satoshi Uchida, Saed Abbasi, Miki Matsui-Masai, Fumihiko Yasui, Akimasa Hayashi, Theofilus A. Tockary, Shiro Akinaga, Michinori Kohara, Kazunori Kataoka
- Organizer
  11th International mRNA Health Conference
- Data Source
  KAKENHI-PROJECT-23H05451
[Presentation] mRNAワクチン、医薬品の基盤技術、応用、今後の展望2023
- Author(s)
  内田　智士
- Organizer
  JSSX-APDD合同ワークショップ第7回
- Invited
- Data Source
  KAKENHI-PROJECT-21H04962
[Presentation] mRNA単体のジェットインジェクションによるCOVID-19ワクチン2023
- Author(s)
  内田智士、Saed Abbasi、正井三貴、林玲匡、Theofilus Tockary、秋永士朗、片岡一則
- Organizer
  第39回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-21H04962
[Presentation] 感染症、がんを標的とした次世代mRNAワクチンのための技術開発2023
- Author(s)
  内田智士
- Organizer
  第 45 回日本バイオマテリアル学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-23H05451
[Presentation] mRNAワクチン、医薬品の基盤技術開発と医療応用2023
- Author(s)
  内田智士
- Organizer
  第72回高分子学会年次大会
- Invited
- Data Source
  KAKENHI-PROJECT-21H04962
[Presentation] Naked mRNA Jet Injection into the Skin Enables the Robust Vaccination against SARS-CoV-2 in Mice and Cynomolgus Monkeys2023
- Author(s)
  Satoshi Uchida, Saed Abbasi, Miki Matsui-Masai, Fumihiko Yasui, Akimasa Hayashi, Theofilus A. Tockary, Shiro Akinaga, Michinori Kohara, Kazunori Kataoka
- Organizer
  11th International mRNA Health Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04962
[Presentation] Small and large animal studies of COVID-19 vaccines based on naked mRNA jet-injection2023
- Author(s)
  Satoshi Uchida, Saed Abbasi, Miki Masai, Akimasa Hayashi, Theofilus Tockary, Shiro Akinaga, Kazunori Kataoka
- Organizer
  日本核酸医薬学会第8回年会
- Data Source
  KAKENHI-PROJECT-21H04962
[Presentation] mRNA分子設計に着目したDDSとワクチン2023
- Author(s)
  内田　智士
- Organizer
  日本薬学会第143回年会
- Invited
- Data Source
  KAKENHI-PROJECT-21K19923
[Presentation] mRNAワクチン、医薬における免疫と医用高分子2023
- Author(s)
  内田　智士
- Organizer
  第73回医用高分子研究会
- Invited
- Data Source
  KAKENHI-PROJECT-21H04962
[Presentation] mRNA医薬品のワクチンを超えた中枢神経系疾患治療への展開2023
- Author(s)
  内田智士
- Organizer
  第41回日本神経治療学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-23H05451
[Presentation] mRNAワクチン、医薬品の基盤技術、応用、今後の展望2023
- Author(s)
  内田　智士
- Organizer
  JSSX-APDD合同ワークショップ第7回
- Invited
- Data Source
  KAKENHI-PROJECT-21K19923
[Presentation] mRNAワクチン、医薬における免疫と医用高分子2023
- Author(s)
  内田　智士
- Organizer
  第73回医用高分子研究会
- Invited
- Data Source
  KAKENHI-PROJECT-21K19923
[Presentation] mRNAワクチンの基礎と次世代に向けた開発2023
- Author(s)
  内田智士
- Organizer
  第36回インフルエンザ研究者交流の会シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-23H05451
[Presentation] Small and large animal studies of COVID-19 vaccines based on naked mRNA jet-injection2023
- Author(s)
  Satoshi Uchida, Saed Abbasi, Miki Masai, Akimasa Hayashi, Theofilus Tockary, Shiro Akinaga, Kazunori Kataoka
- Organizer
  日本核酸医薬学会第8回年会
- Data Source
  KAKENHI-PROJECT-23H05451
[Presentation] mRNAワクチンの基礎と次世代に向けた開発2023
- Author(s)
  内田智士
- Organizer
  第36回インフルエンザ研究者交流の会シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-21H04962
[Presentation] mRNA医薬の再生医療分野への展開とバイオマテリアル2023
- Author(s)
  内田　智士
- Organizer
  第22回再生医療学会
- Invited
- Data Source
  KAKENHI-PROJECT-21H04962
[Presentation] 感染症、がんを標的とした次世代mRNAワクチンのための技術開発2023
- Author(s)
  内田智士
- Organizer
  第55回日本小児感染症学会総会・学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-21H04962
[Presentation] 感染症、がんを標的とした次世代mRNAワクチンのための技術開発2023
- Author(s)
  内田智士
- Organizer
  第 45 回日本バイオマテリアル学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-21H04962
[Presentation] mRNA医薬の再生医療分野への展開とバイオマテリアル2023
- Author(s)
  内田　智士
- Organizer
  第22回再生医療学会
- Invited
- Data Source
  KAKENHI-PROJECT-21K19923
[Presentation] mRNA医薬品のワクチンを超えた中枢神経系疾患治療への展開2023
- Author(s)
  内田智士
- Organizer
  第41回日本神経治療学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-21H04962
[Presentation] mRNA分子設計に着目したDDSとワクチン2023
- Author(s)
  内田　智士
- Organizer
  日本薬学会第143回年会
- Invited
- Data Source
  KAKENHI-PROJECT-21H04962
[Presentation] 今さら聞けないmRNAワクチンの基礎2023
- Author(s)
  内田智士
- Organizer
  第97回日本感染症学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-23H05451
[Presentation] 感染症、がんを標的とした次世代mRNAワクチンの開発2023
- Author(s)
  内田智士
- Organizer
  第14回日本RNAi研究会
- Invited
- Data Source
  KAKENHI-PROJECT-21H04962
[Presentation] 感染症、がんを標的とした次世代mRNAワクチンの開発2023
- Author(s)
  内田智士
- Organizer
  第14回日本RNAi研究会
- Invited
- Data Source
  KAKENHI-PROJECT-23H05451
[Presentation] Next-generation mRNA vaccines against infectious diseases and cancer2023
- Author(s)
  Satoshi Uchida
- Organizer
  14th Indian Scientists Association in Japan (ISAJ) Annual Symposium
- Invited
- Data Source
  KAKENHI-PROJECT-23H05451
[Presentation] 感染症及びがんを標的としたmRNAワクチンの開発2023
- Author(s)
  内田智士
- Organizer
  2023年度遺伝子・デリバリー研究会　夏期セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-23H05451
[Presentation] mRNA vaccine development for infectious disease prevention and cancer treatment2023
- Author(s)
  Satoshi Uchida
- Organizer
  The 18th international Symposium of the institute Network for Biomedical Science
- Invited
- Data Source
  KAKENHI-PROJECT-23H05451
[Presentation] Next-generation mRNA vaccines against infectious diseases and cancer2023
- Author(s)
  内田智士
- Organizer
  "Integrated Science for a Sustainable Society" 14th Indian Scientists Association in Japan (ISAJ) Annual Symposium
- Invited
- Data Source
  KAKENHI-PROJECT-21H04962
[Presentation] 感染症及びがんを標的としたmRNAワクチンの開発2023
- Author(s)
  内田智士
- Organizer
  2023年度遺伝子・デリバリー研究会　夏期セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-21H04962
[Presentation] mRNAワクチンの基礎から最前線まで2022
- Author(s)
  内田　智士
- Organizer
  第56回緑膿菌感染症研究会
- Invited
- Data Source
  KAKENHI-PROJECT-21K19923
[Presentation] 精密設計2本側鎖mRNAを基盤とした汎用的がんmRNAワクチンアジュバントの創製2022
- Author(s)
  内田智士, Theofilus A. Tockary, Saed Abbasi, 正井三貴, 片岡一則
- Organizer
  第44回日本バイオマテリアル学会大会
- Data Source
  KAKENHI-PROJECT-21H04962
[Presentation] mRNA cancer vaccines hybridized with short double-stranded RNA adjuvants2022
- Author(s)
  Satoshi Uchida, Theofilus A. Tockary, Saed Abbasi, Miki Masai, Kazunori Kataoka
- Organizer
  第10回日本核酸医薬学会
- Data Source
  KAKENHI-PROJECT-21K19923
[Presentation] 精密設計2本側鎖mRNAを基盤とした汎用的がんmRNAワクチンアジュバントの創製2022
- Author(s)
  内田智士, Theofilus A. Tockary, Saed Abbasi, 正井三貴, 片岡一則
- Organizer
  第44回日本バイオマテリアル学会大会
- Data Source
  KAKENHI-PROJECT-21K19923
[Presentation] Engineering polymers and mRNA for therapeutic mRNA delivery2022
- Author(s)
  Satoshi Uchida
- Organizer
  13th International Symposium on Polymer Therapeutics 2022
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19923
[Presentation] mRNAワクチンの基礎から最前線まで2022
- Author(s)
  内田　智士
- Organizer
  第56回緑膿菌感染症研究会
- Invited
- Data Source
  KAKENHI-PROJECT-21H04962
[Presentation] mRNA工学を基盤としたmRNAデリバリーとワクチン2022
- Author(s)
  内田　智士
- Organizer
  第38回日本DDS学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-21H04962
[Presentation] mRNA工学を基盤とした次世代mRNAワクチンの創製2022
- Author(s)
  内田　智士
- Organizer
  第43回生体膜と薬物の相互作用シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-21K19923
[Presentation] 生体適合性高分子を基盤とした遺伝子治療とmRNA創薬2022
- Author(s)
  内田　智士
- Organizer
  日経バイオテクセミナー遺伝子治療が抱える課題と新展開
- Invited
- Data Source
  KAKENHI-PROJECT-21H04962
[Presentation] 生体適合性高分子を基盤とした遺伝子治療とmRNA創薬2022
- Author(s)
  内田　智士
- Organizer
  日経バイオテクセミナー遺伝子治療が抱える課題と新展開
- Invited
- Data Source
  KAKENHI-PROJECT-21K19923
[Presentation] mRNA医薬を用いた中枢神経系疾患の治療2022
- Author(s)
  内田　智士
- Organizer
  第41回日本認知症学会学術集会/第37回日本老年精神医学会［合同開催］
- Invited
- Data Source
  KAKENHI-PROJECT-21K19923
[Presentation] mRNA工学を基盤とした次世代mRNAワクチンの創製2022
- Author(s)
  内田　智士
- Organizer
  第43回生体膜と薬物の相互作用シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-21H04962
[Presentation] mRNA 工学を基盤としたナノ DDS とワクチン2022
- Author(s)
  内田　智士
- Organizer
  第 17 回ナノ・バイオメディカル学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-21K19923
[Presentation] mRNA医薬を用いた中枢神経系疾患の治療2022
- Author(s)
  内田　智士
- Organizer
  第41回日本認知症学会学術集会/第37回日本老年精神医学会［合同開催］
- Invited
- Data Source
  KAKENHI-PROJECT-21H04962
[Presentation] Engineering polymers and mRNA for therapeutic mRNA delivery2022
- Author(s)
  Satoshi Uchida
- Organizer
  13th International Symposium on Polymer Therapeutics 2022
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04962
[Presentation] mRNA 工学を基盤としたナノ DDS とワクチン2022
- Author(s)
  内田　智士
- Organizer
  第 17 回ナノ・バイオメディカル学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-21H04962
[Presentation] mRNA工学を基盤としたmRNAデリバリーとワクチン2022
- Author(s)
  内田　智士
- Organizer
  第38回日本DDS学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-21K19923
[Presentation] Hybridizing antigen mRNA with short double-stranded RNA adjuvants for safe and efficient cancer vaccine2022
- Author(s)
  Satoshi Uchida, Theofilus A. Tockary, Saed Abbasi, Miki Masai, Kazunori Kataoka
- Organizer
  10th International mRNA Health Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19923
[Presentation] Hybridizing antigen mRNA with short double-stranded RNA adjuvants for safe and efficient cancer vaccine2022
- Author(s)
  Satoshi Uchida, Theofilus A. Tockary, Saed Abbasi, Miki Masai, Kazunori Kataoka
- Organizer
  10th International mRNA Health Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04962
[Presentation] mRNA cancer vaccines hybridized with short double-stranded RNA adjuvants2022
- Author(s)
  Satoshi Uchida, Theofilus A. Tockary, Saed Abbasi, Miki Masai, Kazunori Kataoka
- Organizer
  第10回核酸医薬学会
- Data Source
  KAKENHI-PROJECT-21H04962
[Presentation] mRNA医薬、遺伝子治療薬の全身投与に向けた取り組み2021
- Author(s)
  内田　智士
- Organizer
  日本核酸医薬学会第6回年会
- Data Source
  KAKENHI-PROJECT-21H04962
[Presentation] 2本鎖PEG-オリゴリシンを用いた肝類洞壁一過的コーティングによるナノ医薬品の体内動態制御2021
- Author(s)
  内田　智士
- Organizer
  第70回高分子討論会
- Data Source
  KAKENHI-PROJECT-21K19923
[Presentation] SDGsとバイオマテリアル2021
- Author(s)
  内田　智士
- Organizer
  第43回日本バイオマテリアル学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-21K19923
[Presentation] COVID-19に対するmRNAワクチン開発の動向と独自の取り組み2021
- Author(s)
  内田　智士
- Organizer
  JAACT2021日本動物細胞工学会
- Invited
- Data Source
  KAKENHI-PROJECT-21H04962
[Presentation] 2本鎖PEGを用いた肝類洞内皮一過的コーティングによる遺伝子治療薬の標的組織集積性向上2021
- Author(s)
  内田智士, A. Dirisala, 籐加珠子, 長田健介, 片岡一則
- Organizer
  第37回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-21K19923
[Presentation] RNA architectonicsを基盤としたmRNA送達とワクチン2021
- Author(s)
  内田　智士
- Organizer
  日本バイオマテリアル学会関西ブロック　第16回若手研究発表会
- Invited
- Data Source
  KAKENHI-PROJECT-21K19923
[Presentation] COVID-19に対するmRNAワクチン開発の動向と独自の取り組み2021
- Author(s)
  内田　智士
- Organizer
  JAACT2021日本動物細胞工学会
- Invited
- Data Source
  KAKENHI-PROJECT-21K19923
[Presentation] メッセンジャーRNAのCOVID-19ワクチンへの応用とその後の展望2021
- Author(s)
  内田　智士
- Organizer
  2020年度　医療産業イノベーションフォーラム，
- Invited
- Data Source
  KAKENHI-PROJECT-17K20086
[Presentation] 2本鎖PEGを用いた肝類洞内皮一過的コーティングによる遺伝子治療薬の標的組織集積性向上2021
- Author(s)
  内田智士, A. Dirisala, 籐加珠子, 長田健介, 片岡一則
- Organizer
  第37回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-21H04962
[Presentation] メッセンジャーRNAのCOVID-19ワクチンへの応用とその後の展望2021
- Author(s)
  内田　智士
- Organizer
  2020年度　医療産業イノベーションフォーラム，
- Invited
- Data Source
  KAKENHI-PROJECT-18H03529
[Presentation] 2本鎖PEG-オリゴリシンを用いた肝類洞壁一過的コーティングによるナノ医薬品の体内動態制御2021
- Author(s)
  内田　智士
- Organizer
  第70回高分子討論会
- Data Source
  KAKENHI-PROJECT-21H04962
[Presentation] Enhanced mRNA Delivery by Polyion Complex Micelles from Flexible Block Ionomers2021
- Author(s)
  H. Cabral, T. Miyazaki, Wenqian Yang, S. Uchida
- Organizer
  MRM2021
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H04524
[Presentation] SDGsとバイオマテリアル2021
- Author(s)
  内田　智士
- Organizer
  第43回日本バイオマテリアル学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-21H04962
[Presentation] mRNA医薬、遺伝子治療薬の全身投与に向けた取り組み2021
- Author(s)
  内田　智士
- Organizer
  日本核酸医薬学会第6回年会
- Data Source
  KAKENHI-PROJECT-21K19923
[Presentation] Polyplex micelles co-loading Cas9 mRNA and single guide RNA exhibit efficient genome editing in the mouse brain2021
- Author(s)
  Uchida S, Abbasi S, Kataoka K
- Organizer
  9th International mRNA Health Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04962
[Presentation] Assembling Several mRNA Strands for Facilitating mRNA Delivery with and without Using Carriers.2021
- Author(s)
  Uchida S, Yoshinaga N, Koji K, Cabral H
- Organizer
  24th Annual Meeting of the American Society of Gene & Cell Therapy
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04962
[Presentation] RNA architectonicsを基盤としたmRNA送達とワクチン2021
- Author(s)
  内田　智士
- Organizer
  日本バイオマテリアル学会関西ブロック　第16回若手研究発表会
- Invited
- Data Source
  KAKENHI-PROJECT-21H04962
[Presentation] Polyplex micelles co-loading Cas9 mRNA and single guide RNA exhibit efficient genome editing in the mouse brain2021
- Author(s)
  Uchida S, Abbasi S, Kataoka K
- Organizer
  9th International mRNA Health Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19923
[Presentation] Assembling Several mRNA Strands for Facilitating mRNA Delivery with and without Using Carriers.2021
- Author(s)
  Uchida S, Yoshinaga N, Koji K, Cabral H
- Organizer
  24th Annual Meeting of the American Society of Gene & Cell Therapy
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19923
[Presentation] mRNA nanomachine for treating rare genetic disorders2020
- Author(s)
  S. Uchida
- Organizer
  India-Japan Webinar on "Rare Genetic Disorders"
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03529
[Presentation] mRNA bundling inside polyion complexes for their physical and biological stabilization2020
- Author(s)
  S. Uchida, K. Koji, N. Yoshinaga, Y. Mochida, T. Hong, H. Cabral
- Organizer
  8th International mRNA Health Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03529
[Presentation] mRNA bundling inside polyion complexes for their physical and biological stabilization2020
- Author(s)
  S. Uchida, K. Koji, N. Yoshinaga, Y. Mochida, T. Hong, H. Cabral
- Organizer
  8th International mRNA Health Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K20086
[Presentation] Development of mRNA polyplex micelles through engineering polymers and mRNA for in vivo therapeutic applications2020
- Author(s)
  S. Uchida
- Organizer
  IBS CNM Seminar
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03529
[Presentation] DNA、mRNAのex vivo導入による細胞治療の効果向上2020
- Author(s)
  内田　智士
- Organizer
  第36回日本DDS学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18H03529
[Presentation] Development of polymeric micelles for in vivo mRNA delivery through stable complexation with flexible block catiomers2020
- Author(s)
  Takuya Miyazaki, Satoshi Uchida, Horacio Cabral
- Organizer
  2nd International Online-Conference on Nanomaterials
- Invited
- Data Source
  KAKENHI-PROJECT-20H04524
[Presentation] 新型コロナウイルスや未来のパンデミックに対するmRNAナノワクチンの開発2020
- Author(s)
  内田　智士
- Organizer
  第7回COINSシンポジウム　～小さく寄り添い大きく守る、未来の医療はすぐそこに～
- Invited
- Data Source
  KAKENHI-PROJECT-17K20086
[Presentation] mRNA nanomachine for treating rare genetic disorders2020
- Author(s)
  S. Uchida
- Organizer
  India-Japan Webinar on "Rare Genetic Disorders"
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K20086
[Presentation] Development of mRNA polyplex micelles through engineering polymers and mRNA for in vivo therapeutic applications2020
- Author(s)
  S. Uchida
- Organizer
  IBS CNM Seminar
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K20086
[Presentation] RNA構造に着目したメッセンジャーRNA 医薬の機能化2020
- Author(s)
  内田　智士
- Organizer
  第69回高分子討論会
- Invited
- Data Source
  KAKENHI-PROJECT-17K20086
[Presentation] RNAオリゴマーを用いたmRNA修飾法の開発とmRNA送達、ワクチンへの展開2020
- Author(s)
  内田　智士
- Organizer
  核酸医薬シンポジウム2020
- Invited
- Data Source
  KAKENHI-PROJECT-17K20086
[Presentation] RNA構造に着目したメッセンジャーRNA 医薬の機能化2020
- Author(s)
  内田　智士
- Organizer
  第69回高分子討論会
- Invited
- Data Source
  KAKENHI-PROJECT-18H03529
[Presentation] 新型コロナウイルスや未来のパンデミックに対するmRNAナノワクチンの開発2020
- Author(s)
  内田　智士
- Organizer
  第7回COINSシンポジウム　～小さく寄り添い大きく守る、未来の医療はすぐそこに～
- Invited
- Data Source
  KAKENHI-PROJECT-18H03529
[Presentation] DNA、mRNAのex vivo導入による細胞治療の効果向上2020
- Author(s)
  内田　智士
- Organizer
  第36回日本DDS学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-17K20086
[Presentation] mRNA structuring for stabilizing mRNA nanocarriers and improving their delivery efficiency2020
- Author(s)
  Satoshi Uchida, Kyoko Koji, Naoto Yoshinaga, Yuki Mochida, Taehun Hong, Horacio Cabral
- Organizer
  2nd International Online-Conference on Nanomaterials
- Invited
- Data Source
  KAKENHI-PROJECT-20H04524
[Presentation] Preparation of nanoassemblies from several mRNA strands for enhancing nuclease stability.2020
- Author(s)
  S. Uchida, N. Yoshinaga, E. Cho, K. Koji, K. Kataoka, H. Cabral
- Organizer
  International Symposium on Biomedical Materials for Drug/Gene Delivery
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K20086
[Presentation] RNAオリゴマーを用いたmRNA修飾法の開発とmRNA送達、ワクチンへの展開2020
- Author(s)
  内田　智士
- Organizer
  核酸医薬シンポジウム2020
- Invited
- Data Source
  KAKENHI-PROJECT-18H03529
[Presentation] Preparation of nanoassemblies from several mRNA strands for enhancing nuclease stability.2020
- Author(s)
  S. Uchida, N. Yoshinaga, E. Cho, K. Koji, K. Kataoka, H. Cabral
- Organizer
  International Symposium on Biomedical Materials for Drug/Gene Delivery
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03529
[Presentation] Mechanistic analyses of polymer/lipid-based gene transfection processes through membrane integrity assay using proton sensing transistor2020
- Author(s)
  Eger Boonstra, Hiroaki Hatano, Tatsuro Goda, Satoshi Uchida, Horacio Cabral, Yuji Miyahara
- Organizer
  2nd International Online-Conference on Nanomaterials
- Data Source
  KAKENHI-PROJECT-20H04524
[Presentation] 複複数のmRNA鎖を束ねることで生体内酵素分解を抑制させたmRNAナノ集合体の開発2019
- Author(s)
  内田智士、吉永直人、趙オル、小路恭子、長田健介、片岡一則、Horacio Cabral
- Organizer
  第41回バイオマテリアル学会大会
- Data Source
  KAKENHI-PROJECT-17K20086
[Presentation] 複複数のmRNA鎖を束ねることで生体内酵素分解を抑制させたmRNAナノ集合体の開発2019
- Author(s)
  内田智士、吉永直人、趙オル、小路恭子、長田健介、片岡一則、Horacio Cabral
- Organizer
  第41回バイオマテリアル学会大会
- Data Source
  KAKENHI-PROJECT-18H03529
[Presentation] Nanoengineering mRNA through short RNA hybridization for biomedical application2019
- Author(s)
  S. Uchida
- Organizer
  1st Thailand-Australia-Japan Joint Research Meeting on Nanomedicine
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03529
[Presentation] Hybridization of mRNA with a small number of short cholesteryl RNA oligonucleotides for tight mRNA packaging to polyplex micelles.2019
- Author(s)
  S. Uchida, N. Yoshinaga, H. Cabral, K. Kataoka
- Organizer
  19th Smposium for gene design and delivery
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03529
[Presentation] Nanoengineering mRNA through short RNA hybridization for biomedical application2019
- Author(s)
  S. Uchida
- Organizer
  1st Thailand-Australia-Japan Joint Research Meeting on Nanomedicine
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K20086
[Presentation] 複数のmRNA鎖からなるナノ集合体を用いたmRNA安定化とその生体内投与2019
- Author(s)
  内田智士、吉永直人、趙オル、小路恭子、長田健介、片岡一則、Horacio Cabral
- Organizer
  第35回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-18H03529
[Presentation] Stabilization of mRNA polyplex micelles for in vivo delivery by engineering mRNA2019
- Author(s)
  S. Uchida, N. Yoshinaga, H. Cabral, K. Kataoka
- Organizer
  2nd G’L’owing Polymer Symposium in KANTO
- Data Source
  KAKENHI-PROJECT-18H03529
[Presentation] Mechanistic analyses of polymer/lipid-based gene transfection processes through membrane integrity assay using proton sensing transistor2019
- Author(s)
  E. Boonstra, H. Hatano, T. Goda, S. Uchida, H. Cabral, Y. Miyahara
- Organizer
  4th International Symposium on Biomedical Engineering, ISBE 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19901
[Presentation] 複数のmRNA鎖からなるナノ集合体を用いたmRNA安定化とその生体内投与2019
- Author(s)
  内田智士、吉永直人、趙オル、小路恭子、長田健介、片岡一則、Horacio Cabral
- Organizer
  第35回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-17K20086
[Presentation] 複数のmRNA鎖を束ねたナノ集合体の開発と生体内投与2019
- Author(s)
  内田智士、吉永直人、趙オル、小路恭子、長田健介、片岡一則、Horacio Cabral
- Organizer
  日本核酸医薬学会第5回年会
- Data Source
  KAKENHI-PROJECT-18H03529
[Presentation] 複数のmRNA鎖を束ねたナノ集合体の開発と生体内投与2019
- Author(s)
  内田智士、吉永直人、趙オル、小路恭子、長田健介、片岡一則、Horacio Cabral
- Organizer
  日本核酸医薬学会第5回年会
- Data Source
  KAKENHI-PROJECT-17K20086
[Presentation] Development of novel flexible block catiomers for forming stable polyion complex micelles with mRNA directed to in vivo applications2019
- Author(s)
  W. Yang, T. Miyazaki, S. Uchida, H. Cabral
- Organizer
  2nd G'L'owing Polymer Symposium in Kanto
- Data Source
  KAKENHI-PROJECT-18K19901
[Presentation] Stabilization of mRNA polyplex micelles for in vivo delivery by engineering mRNA2019
- Author(s)
  S. Uchida, N. Yoshinaga, H. Cabral, K. Kataoka
- Organizer
  2nd G’L’owing Polymer Symposium in KANTO
- Data Source
  KAKENHI-PROJECT-17K20086
[Presentation] Hybridization of mRNA with a small number of short cholesteryl RNA oligonucleotides for tight mRNA packaging to polyplex micelles.2019
- Author(s)
  S. Uchida, N. Yoshinaga, H. Cabral, K. Kataoka
- Organizer
  19th Smposium for gene design and delivery
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K20086
[Presentation] グアニジノ基修飾によるmRNA搭載ポリイオンコンプレックスの機能向上2018
- Author(s)
  堀真緒, 吉永直人、内田智士、H. Cabral、片岡一則
- Organizer
  第67回高分子年次大会
- Data Source
  KAKENHI-PROJECT-18K19901
[Presentation] Incorporation of Immunostimulatory Property to Messenger RNA Molecule by Hybridizing RNA to Poly A Sequence for Effective Vaccination2018
- Author(s)
  Satoshi Uchida, Keiji Itaka, Kazunori Kataoka
- Organizer
  21st annual meeting ASGCT
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03529
[Presentation] Design of polyplex micelles with phenylboronate ester cross-linking in the core exerting promoted gene transfection through responsivity to intracellular pH and ATP concentration2018
- Author(s)
  N. Yoshinaga, M. Naito, S. Uchida, H. Cabral, K. Osada, K. Kataoka
- Organizer
  256th ACS National Meeting & Exposition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19901
[Presentation] コレステロール修飾相補鎖RNAを用いたmRNA搭載高分子ミセル安定化2018
- Author(s)
  内田　智士、吉永　直人、長田　健介、位髙　啓史、Horacio Cabral、片岡　一則
- Organizer
  第40回日本バイオマテリアル学会大会
- Data Source
  KAKENHI-PROJECT-18H03529
[Presentation] Therapeutic application of mRNA delivery using polyplex micelles2018
- Author(s)
  Satoshi Uchida, Keiji Itaka, Kazunori Kataoka
- Organizer
  Finland-Japan Workshop: The next generation medical engineering in biomaterials
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K20086
[Presentation] Incorporation of Immunostimulatory Property to Messenger RNA Molecule by Hybridizing RNA to Poly A Sequence for Effective Vaccination2018
- Author(s)
  Satoshi Uchida, Keiji Itaka, Kazunori Kataoka
- Organizer
  21st annual meeting ASGCT
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K20086
[Presentation] コレステロール基修飾短鎖RNAオリゴマーを用いたmRNA内包高分子ミセルの安定化2018
- Author(s)
  吉永直人,内田智士、Cabral Horacio、長田健介、片岡一則
- Organizer
  第67回高分子年次大会
- Data Source
  KAKENHI-PROJECT-18K19901
[Presentation] 高分子ミセルを用いたメッセンジャー(m)RNA医薬の送達と疾患治療への展開2018
- Author(s)
  内田　智士
- Organizer
  第34回日本ＤＤＳ学会学術集会
- Data Source
  KAKENHI-PROJECT-18H03529
[Presentation] 免疫賦活化アジュバント機能一体型 2本鎖mRNAワクチン2018
- Author(s)
  内田智士、位髙啓史、片岡一則
- Organizer
  日本核酸医薬学会第4回年会
- Data Source
  KAKENHI-PROJECT-17K20086
[Presentation] 免疫賦活化アジュバント機能一体型 2本鎖mRNAワクチン2018
- Author(s)
  内田　智士、位髙　啓史、片岡　一則
- Organizer
  日本核酸医薬学会第4回年会
- Data Source
  KAKENHI-PROJECT-18H03529
[Presentation] 標題コレステロール修飾相補鎖RNAを用いたmRNA搭載高分子ミセル安定化2018
- Author(s)
  内田智士、吉永直人、長田健介、位髙啓史、Horacio Cabral、片岡一則
- Organizer
  第40回日本バイオマテリアル学会大会
- Data Source
  KAKENHI-PROJECT-17K20086
[Presentation] 少数のコレステロール修飾RNAオリゴマーにより誘起されるmRNA内包高分子ミセルの構造安定化およびマウス肺局所投与への応用2018
- Author(s)
  吉永直人、内田智士、長田健介、位髙啓史、H. Cabral、片岡一則
- Organizer
  第35回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-18K19901
[Presentation] 高分子ミセルを用いたメッセンジャー(m)RNA医薬の送達と疾患治療への展開2018
- Author(s)
  内田智士
- Organizer
  第34回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-17K20086
[Presentation] Therapeutic application of mRNA delivery using polyplex micelles2018
- Author(s)
  Satoshi Uchida, Keiji Itaka, Kazunori Kataoka
- Organizer
  Finland-Japan Workshop: The next generation medical engineering in biomaterials
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03529
[Presentation] 高分子ミセルを用いたメッセンジャーRNAデリバリー2017
- Author(s)
  内田智士
- Organizer
  理研シンポジウム：理研/iCONM/物材研　医工学ネットワーク
- Invited
- Data Source
  KAKENHI-PROJECT-15K20962
[Presentation] 高分子ミセルを用いたメッセンジャーRNAデリバリー2017
- Author(s)
  内田智士
- Organizer
  理研シンポジウム：理研/iCONM/物材研　医工学ネットワーク
- Invited
- Data Source
  KAKENHI-PROJECT-17K20086
[Presentation] 免疫賦活化能を向上させた2本鎖メッセンジャーRNAワクチンの開発2017
- Author(s)
  内田智士、吉永直人、柳原歌代子、弓場獎司、位髙啓史、片岡一則
- Organizer
  第39回日本バイオマテリアル学会大会
- Data Source
  KAKENHI-PROJECT-17K20086
[Presentation] mRNA搭載ナノミセルを用いた抗アミロイドβ単鎖抗体導入によるアルツハイマー病治療2017
- Author(s)
  内田智士、F. Perche、秋葉宏樹、位髙啓史、津本浩平、片岡一則
- Organizer
  日本核酸医薬学会第3回年会
- Data Source
  KAKENHI-PROJECT-17K20086
[Presentation] mRNA搭載ナノミセルを用いた抗アミロイドβ単鎖抗体導入によるアルツハイマー病治療2017
- Author(s)
  内田智士、F. Perche、秋葉宏樹、位髙啓史、津本浩平、片岡一則
- Organizer
  日本核酸医薬学会第3回年会
- Data Source
  KAKENHI-PROJECT-15K20962
[Presentation] 抗アミロイドβ単鎖抗体発現mRNA搭載ナノミセルを用いたアルツハイマー病治療2017
- Author(s)
  内田智士、F. Perche、秋葉宏樹、位髙啓史、津本浩平、片岡一則
- Organizer
  第33回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-17K20086
[Presentation] 免疫賦活化能を向上させた2本鎖メッセンジャーRNAワクチンの開発2017
- Author(s)
  内田智士、吉永直人、柳原歌代子、弓場獎司、位髙啓史、片岡一則
- Organizer
  第39回日本バイオマテリアル学会大会
- Data Source
  KAKENHI-PROJECT-15K20962
[Presentation] 抗アミロイドβ単鎖抗体発現mRNA搭載ナノミセルを用いたアルツハイマー病治療2017
- Author(s)
  内田智士、F. Perche、秋葉宏樹、位髙啓史、津本浩平、片岡一則
- Organizer
  第33回DDS学会学術大会
- Data Source
  KAKENHI-PROJECT-25000006
[Presentation] mRNA搭載ナノミセルを用いた抗アミロイドβ単鎖抗体導入によるアルツハイマー病治療2017
- Author(s)
  内田智士、F. Perche、秋葉宏樹、位髙啓史、津本浩平、片岡一則
- Organizer
  日本核酸医薬学会第3回年会
- Data Source
  KAKENHI-PROJECT-25000006
[Presentation] 抗アミロイドβ単鎖抗体発現mRNA搭載ナノミセルを用いたアルツハイマー病治療2017
- Author(s)
  内田智士、F. Perche、秋葉宏樹、位髙啓史、津本浩平、片岡一則
- Organizer
  第33回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-15K20962
[Presentation] Development of polyplex nanomicelles for systemic messenger RNA delivery targeting pancreatic cancer.2016
- Author(s)
  S. Uchida, H. Kinoh, T. Ishii, A. Matsui, H. Uchida, K. Itaka, K. Kataoka.
- Organizer
  Gorden Research Conference (Drug Carriers in Medicine & Biology)
- Place of Presentation
  Waterville Valley, NH, USA
- Year and Date
  2016-08-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K20962
[Presentation] Intracerebral administration of mRNA for treating brain diseases : An animal study for augmenting clearance of beta-amyloid using neprilysin mRNA2016
- Author(s)
  K. Itaka, C. -Y. Lin, S. Uchida, K. Kataoka
- Organizer
  The 4th International mRNA Conference
- Place of Presentation
  Westin Boston Waterfront (Massachusetts, USA)
- Year and Date
  2016-11-02
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25000006
[Presentation] コレステロール修飾ナノミセルを用いたmRNA全身投与による膵臓がん治療2016
- Author(s)
  内田智士、喜納宏昭、石井武彦、内田寛邦、松井秋倫、位髙啓史、片岡一則
- Organizer
  第32回日本DDS学会学術集会
- Place of Presentation
  静岡県　静岡市
- Year and Date
  2016-06-30
- Data Source
  KAKENHI-PROJECT-15K20962
[Presentation] Anti-angiogenic therapy for pancreatic cancer by systemic delivery of messenger RNA using polyplex nanomicelle.2016
- Author(s)
  S. Uchida, H. Kinoh, T. Ishii, A. Matsui, T. A. Tockary, K. M. Takeda, H. Uchida, K. Osada, K. Itaka, K. Kataoka
- Organizer
  ASGCT 19th Annual Meeting
- Place of Presentation
  Washington, DC, USA
- Year and Date
  2016-05-06
- Data Source
  KAKENHI-PROJECT-15K20962
[Presentation] Messenger RNA-based therapy for an apoptosis-related disease in the liver.2015
- Author(s)
  S. Uchida, A. Matsui, K Kataoka, K. Itaka
- Organizer
  ESGCT and FSGT Collaborative Congress
- Place of Presentation
  Helsinki, Finland
- Year and Date
  2015-09-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K20962
[Presentation] Polyplex namomicelles assembled with neprilysin mRNA augmented clearance of beta-amyloid peptide from intracerebroventricular infusion2015
- Author(s)
  C. -Y. Lin, S. Uchida, K. Itaka, K. Kataoka
- Organizer
  2015 ESGCT and FSGT Collaborative Congress
- Place of Presentation
  Finlandia Hall (Helsinki, Finland)
- Year and Date
  2015-09-19
- Description
  【発表確定】
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25000006
[Presentation] mRNAの全身投与に向けた高分子ナノミセルの開発と膵臓がん治療への応用2015
- Author(s)
  内田智士、喜納宏昭、石井武彦、松井秋倫、位髙啓史、片岡一則
- Organizer
  第37回日本バイオマテリアル学会大会
- Place of Presentation
  京都府京都市
- Year and Date
  2015-11-09
- Data Source
  KAKENHI-PROJECT-15K20962
[Presentation] Treating neurological disorders by in vivo mRNA introduction using polyplex nanomicelles2015
- Author(s)
  K. Itaka, M. Baba, H. Uchida, S. Uchida, K. Kataoka
- Organizer
  Biomaterials International 2015
- Place of Presentation
  Howard Beach Resort-Kenting (Kenting, Taiwan)
- Year and Date
  2015-06-04
- Description
  【発表確定】
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25000006
[Presentation] N置換ポリアスバルタマイド側鎖の化学構造がmRNAポリプレックスの細胞内安定性及び発現持続性に及ぼす影響2015
- Author(s)
  内田寛邦, 位高啓史, 宮田完二郎, 西山伸宏, 片岡一則
- Organizer
  第1回日本核酸医薬学会大会
- Place of Presentation
  京都テルサ(京都府京都市)
- Year and Date
  2015-12-01
- Description
  【発表確定】
- Data Source
  KAKENHI-PROJECT-25000006
[Presentation] Messenger RNA (mRNA)-based gene therapy for introducing anti-apoptotic factor.2015
- Author(s)
  S. Uchida, A. Matsui, K. Itaka, K Kataoka
- Organizer
  American Society of Gene and Cell Therapy (ASGCT) 18th Annual Meeting
- Place of Presentation
  New Orleans, USA
- Year and Date
  2015-05-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K20962
[Presentation] Messenger RNA (mRNA) -based gene therapy for introduction of an anti-apoptotic factor2015
- Author(s)
  S. Uchida, A. Matsui, K. Itaka, K. Kataoka
- Organizer
  ASGCT 18th Annual Meeting
- Place of Presentation
  Hyatt Regency New Orleans (New Orleans, Louisiana, USA)
- Year and Date
  2015-05-15
- Description
  【発表確定】
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25000006
[Presentation] 転写因子mRNAの関節内投与による変形性関節症治療2015
- Author(s)
  位高啓史, H. Aini, 内田寛邦, 内田智士, 鄭雄一, 大庭伸介, 片岡一則
- Organizer
  第1回日本核酸医薬学会大会
- Place of Presentation
  京都テルサ(京都府京都市)
- Year and Date
  2015-12-01
- Description
  【発表確定】
- Data Source
  KAKENHI-PROJECT-25000006
[Presentation] Messenger RNA-based therapy for an apoptosis-related disease in the liver2015
- Author(s)
  S. Uchida, A. Matsui, K. Itaka, K. Kataoka
- Organizer
  2015 ESGCT and FSGT Collaborative Congress
- Place of Presentation
  Finlandia Hall (Helsinki, Finland)
- Year and Date
  2015-09-18
- Description
  【発表確定】
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25000006
[Presentation] メッセンジャーRNAを用いた新しい遺伝子治療と再生医療への応用2015
- Author(s)
  位高啓史, 内田智士, 片岡一則
- Organizer
  第31回日本DDS学会学術集会
- Place of Presentation
  京王プラザホテル(東京都新宿区)
- Year and Date
  2015-07-03
- Description
  【発表確定】
- Invited
- Data Source
  KAKENHI-PROJECT-25000006
[Presentation] 脳組織内での標的選択性向上を目指した高分子ミセル型ナノキャリアの開発2015
- Author(s)
  堀真緒, 内藤瑞, 内田智士, 安楽泰孝, 片岡一則
- Organizer
  第37回日本バイオマテリアル学会大会
- Place of Presentation
  京都テルサ(京都府京都市)
- Year and Date
  2015-11-09
- Description
  【発表確定】
- Data Source
  KAKENHI-PROJECT-25000006
[Presentation] 非ウイルス性遺伝子導入とスフェロイド細胞移植の融合システムを用いた脊髄損傷治療2014
- Author(s)
  内田智士, 位髙啓史, 早川謙太郎, 緒方徹, 片岡一則
- Organizer
  アンチセンス・遺伝子・デリバリーシンポジウム2014
- Place of Presentation
  東京医科歯科大学, 東京
- Year and Date
  2014-09-09
- Data Source
  KAKENHI-PROJECT-25882011
[Presentation] Treatment of spinal cord injury by transplantation of BDNF-transfected mesenchymal stem cell spheroids.2014
- Author(s)
  S. Uchida, K. Itaka, K. Hayakawa, T. Ogata, K. Kataoka
- Organizer
  17th Annual Meeting of American Society of Gene & Cell Therapy (ASGCT)
- Place of Presentation
  Washington DC, USA
- Year and Date
  2014-05-22
- Data Source
  KAKENHI-PROJECT-25882011
[Presentation] mRNA投与による生体内での細胞アポトーシスシグナル制御2014
- Author(s)
  内田智士, 松井秋倫, 石井武彦, 位髙啓史, 片岡一則
- Organizer
  第30回日本DDS学会学術集会
- Place of Presentation
  慶應義塾大学, 東京
- Year and Date
  2014-07-30
- Data Source
  KAKENHI-PROJECT-25882011
[Presentation] 新しい治療用核酸としてのmRNA2014
- Author(s)
  位髙啓史, 内田智士, 片岡一則
- Organizer
  第30回日本DDS学会学術集会
- Place of Presentation
  慶應義塾大学(東京都港区)
- Year and Date
  2014-07-31
- Invited
- Data Source
  KAKENHI-PROJECT-25000006
[Presentation] mRNA投与による生体内での細胞アポトーシスシグナル制御2014
- Author(s)
  内田智士, 松井秋倫, 石井武彦, 位髙啓史, 片岡一則
- Organizer
  第30回日本DDS学会学術集会
- Place of Presentation
  慶應義塾大学(東京都港区)
- Year and Date
  2014-07-30
- Data Source
  KAKENHI-PROJECT-25000006
[Presentation] スフェロイド細胞移植と遺伝子導入の融合システム開発と脊髄損傷治療への応用2014
- Author(s)
  内田智士, 位髙啓史, 早川謙太郎, 緒方徹, 片岡一則
- Organizer
  第36回日本バイオマテリアル学会
- Place of Presentation
  タワーホール船堀, 東京
- Year and Date
  2014-11-18
- Data Source
  KAKENHI-PROJECT-25882011
[Presentation] Enhanced nucleic acids delivery by fine-tuning repeated aminoethylene structures in polyaspartamide side chain2013
- Author(s)
  K. Miyata, H. Uchida, N. Nishiyama, K. Kataoka
- Organizer
  The 4th Asian Symposium on Advanced Materials - Chemistry, Physics & Biomedicine of Functional and Novel Materials
- Place of Presentation
  National Taiwan University of Science and Technology (Taipei, Taiwan)
- Year and Date
  2013-10-23
- Data Source
  KAKENHI-PROJECT-25000006
[Presentation] 高分子ナノミセルを用いた中枢神経系への安全かつ持続的なmRNA導入2013
- Author(s)
  内田智士、位髙啓史、内田寛邦、石井武彦、福島重人、長田健介、片岡一則
- Organizer
  第13回遺伝子・デリバリー研究会シンポジウム
- Place of Presentation
  帝京天学薬学部板橋キャンパス(東京都板橋区)
- Year and Date
  2013-05-11
- Data Source
  KAKENHI-PROJECT-25000006
[Presentation] Regulation of mRNA immunogenicity by nanomicelle encapsulation for in vivo mRNA delivery2013
- Author(s)
  S. Uchida, K. Itaka, H. Uchida, K. Hayakawa, T. Ogata, T. Ishii, S. Fukushima, K. Osada, K. Kataoka
- Organizer
  40th Annual Meeting & Exposition of the Controlled Release Society
- Place of Presentation
  Hawaii Convention Center (Honolulu, Hawaii, USA)
- Year and Date
  2013-07-21
- Data Source
  KAKENHI-PROJECT-25000006
[Presentation] In vivo mRNA delivery using a novel non-viral carrier, polyplex nanomicelle2013
- Author(s)
  K. Itaka, S. Uchida, K. Kataoka
- Organizer
  FRONTIERS2013 - Joint EPFL/University of Tokyo Symposium on "Frontiers in Nanomedicine and Imaging"
- Place of Presentation
  Swiss Federal Institute of Technology (Lausanne, Switzerland)
- Year and Date
  2013-06-21
- Data Source
  KAKENHI-PROJECT-25000006
[Presentation] Hydrodynamic delivery of mRNA to mouse liver using polyplex nano micelle.
- Author(s)
  S. Uchida, K. Itaka, K. Kataoka
- Organizer
  FIRST合同国際シンポジウム難治がんを克服する―次世代の診断、治療が描く未来 Overcoming Intractable Cancer- a new path to the future
- Place of Presentation
  東京大学、東京
- Data Source
  KAKENHI-PROJECT-25882011
[Presentation] BDNF遺伝子導入3次元スフェロイド細胞移植による脊髄損傷治療
- Author(s)
  内田智士、早川謙太郎、緒方徹、片岡一則、位高啓史
- Organizer
  第13回日本再生医療学会総会
- Place of Presentation
  国立京都国際会館、京都
- Data Source
  KAKENHI-PROJECT-25882011
[Presentation] 3次元スフェロイド培養と非ウイルス性遺伝子ベクターを組み合わせた新規細胞移植システムの開発
- Author(s)
  内田智士、位高啓史、遠藤泰輔、柳原歌代子、野本貴大、石井武彦、松本有、片岡一則
- Organizer
  第35回日本バイオマテリアル学会大会
- Place of Presentation
  タワーホール船堀、東京
- Data Source
  KAKENHI-PROJECT-25882011

1. NISHIYAMA Nobuhiro (10372385)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
2. MIYATA Kanjiro (50436523)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
3. Cabral Horacio (10533911)

# of Collaborated Projects: 2 results

# of Collaborated Products: 11 results
4. 弓場英司 (80582296)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. KATAOKA Kazunori (00130245)

# of Collaborated Projects: 1 results

# of Collaborated Products: 30 results
6. YOKOTA Takanori (90231688)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. ITAKA Keiji (60292926)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
8. TSUMOTO Kouhei (90271866)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
9. OSADA Kensuke (10396947)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
10. Ishii Takehiko (80415075)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
11. ANRAKU Yasutaka (60581585)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. MATSUMOTO Yu (80548553)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
13. 阿部洋 (80415067)

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14. 大庭誠 (20396716)

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17. 原島秀吉 (00183567)

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18. 佐藤悠介 (10735624)

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# of Collaborated Projects: 1 results

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21. SAITO Taku

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# of Collaborated Products: 1 results
22. GODA Tatsuro

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# of Collaborated Products: 1 results
23. NAGATOISHI Satoru

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# of Collaborated Products: 1 results
24. 位高啓史

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# of Collaborated Products: 17 results
25. 中川泰宏

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# of Collaborated Products: 1 results
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# of Collaborated Products: 1 results
27. 野本貴大

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# of Collaborated Products: 1 results
28. 緒方徹

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29. 山田直生

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Uchida Satoshi 内田 智士

UCHIDA Satoshi 内田 智士

Research Projects

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mRNA医薬、進化分子工学、深層学習を基盤としたタンパク質間相互作用標的創薬Principal Investigator

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Pioneering Treatment of Antimicrobial Resistance through Nebulization of Single-Chain Antibody mRNAPrincipal Investigator

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Activated mRNA delivery system based on core-shell structured LNP with smart polymers

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Development and therapeutic application of short mRNA therapeutics based on mRNA engineeringPrincipal Investigator

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In situ PEGylation of extracellular DNA using functional peptides for anti-inflammatory therapyPrincipal Investigator

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Cancer immunotherapy by in vivo generation of CAR T cells based on targeted mRNA delivery

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Development of immunostimulatory mRNA and lymphoid tissue-targeting carriers for cancer vaccinePrincipal Investigator

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Development of mRNA drug with RNA type aptamer conferring cell type specific translation activation function

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Determination of therapeutic factors using extracellular vesicles secreted from 3D-cultured stem cellsPrincipal Investigator

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In vivo suppression of apoptosis signaling using mRNA therapeutics for the treatment of ischemic diseasesPrincipal Investigator

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mRNA-based introduction of anti-apoptotic factors using nanomicelle for therapeutic applicationPrincipal Investigator

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Development of Polymeric Micelles for Brain-Targeted Delivery of Nucleic Acid Drugs to Treat Intractable Neurological Diseases

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[Book] Messenger RNA Therapeutics2022

Author(s)

Total Pages

Uchida Satoshi 内田智士

UCHIDA Satoshi 内田智士

[Book] 高分子ナノミセルを用いた生体へのin vivo mRNAデリバリートランスレーショナルリサーチを支援する遺伝子医学MOOK30号今、着実に実り始めた遺伝子治療－最新研究と今後の展開2016