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Mizuuchi Yusuke  水内 祐介

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MIZUUCHI Yusuke  水内 祐介

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Researcher Number 20849088
Affiliation (Current) 2025: 九州大学, 大学病院, 講師
Affiliation (based on the past Project Information) *help 2019 – 2024: 九州大学, 大学病院, 助教
Review Section/Research Field
Principal Investigator
Basic Section 55020:Digestive surgery-related / 0905:Surgery of the organs maintaining homeostasis and related fields
Except Principal Investigator
Basic Section 50020:Tumor diagnostics and therapeutics-related / Basic Section 55010:General surgery and pediatric surgery-related / Basic Section 55020:Digestive surgery-related
Keywords
Principal Investigator
大腸癌 / 腸内細菌叢 / heterogeneity / 微小環境 / シングルセル解析 / 発癌予防 / 免疫エコシステム / scRNA-seq / Microbiome / 腫瘍微小環境 … More / 大腸がん / scRNAseq / 腫瘍内heterogeneity / Transcriptome解析 / Drop-Seq技術 … More
Except Principal Investigator
膵癌 / オルガノイド / 腫瘍免疫 / PDXマウス / 癌間質相互作用 / 膵星細胞 / CAF / 腫瘍微小環境 / 微小環境 / 腫瘍関連好中球 / マイクロバイオーム / 個別化治療 / 免疫治療 / MHCクラスII / CD4陽性T細胞 / 食道癌 / De novo searching / Direct identification / 膵癌HLAリガンドーム / 化合物スクリーニング / 癌関連線維芽細胞 / 癌微小環境 / 膵癌間質 / 治療抵抗性 / オートファジー / 間質標的治療 / PSC / 薬剤スクリーニング / 微小環境因子 / desmoplasia / テーラーメイド治療 / Pin1 / 化合物ライブラリー / ハイスループットスクリーニング / Niche factors Less
  • Research Projects

    (8 results)
  • Research Products

    (5 results)
  • Co-Researchers

    (20 People)
  •  Direct identificationによる膵癌HLAリガンドームの解明

    • Principal Investigator
      藤原 謙次
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Kyushu University
  •  MHCクラスⅡ陽性食道癌-細胞障害性CD4陽性T細胞を軸にした新規治療戦略

    • Principal Investigator
      堀岡 宏平
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      Kyushu University
  •  大腸癌発癌過程における粘膜特異的免疫エコシステムの解明Principal Investigator

    • Principal Investigator
      水内 祐介
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Kyushu University
  •  マイクロバイオームと腫瘍関連好中球から見た膵がんミニエコシステム

    • Principal Investigator
      池永 直樹
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Kyushu University
  •  Elucidation of the mechanism by which the colorectal cancer microenvironment is involved in carcinogenesis using scRNAseq and gut microbiota analysisPrincipal Investigator

    • Principal Investigator
      MIZUUCHI Yusuke
    • Project Period (FY)
      2020 – 2021
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Kyushu University
  •  Construction of an anticancer drug screening system using human pancreatic cancer tissue and therapeutic application

    • Principal Investigator
      KOZONO Shingo
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Kyushu University
  •  Construction of drug discovery library using PDX-3D method and discovery of novel therapeutic agents for pancreatic cancer

    • Principal Investigator
      MIZUMOTO Kazuhiro
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      International University of Health and Welfare
      Kyushu University
  •  Drop-sequence of colon cancer to reveal heterogeneity of tumor microenvironmentPrincipal Investigator

    • Principal Investigator
      MIZUUCHI Yusuke
    • Project Period (FY)
      2019 – 2020
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Review Section
      0905:Surgery of the organs maintaining homeostasis and related fields
    • Research Institution
      Kyushu University

All 2022 2021

All Journal Article Presentation

  • [Journal Article] Subtypes in pancreatic ductal adenocarcinoma based on niche factor dependency show distinct drug treatment responses2022

    • Author(s)
      Shinkawa Tomohiko、Ohuchida Kenoki、Mochida Yuki、Sakihama Kukiko、Iwamoto Chika、Abe Toshiya、Ideno Noboru、Mizuuchi Yusuke、Shindo Koji、Ikenaga Naoki、Moriyama Taiki、Nakata Kohei、Oda Yoshinao、Nakamura Masafumi
    • Journal Title

      Journal of Experimental Clinical Cancer Research

      Volume: 41 Issue: 1 Pages: 89-89

    • DOI

      10.1186/s13046-022-02301-9

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09125, KAKENHI-PROJECT-20K16361, KAKENHI-PROJECT-20K22817, KAKENHI-PROJECT-20K22955, KAKENHI-PROJECT-19H03732, KAKENHI-PROJECT-20H03530, KAKENHI-PROJECT-20H03754, KAKENHI-PROJECT-20K09106, KAKENHI-PROJECT-21K08800, KAKENHI-PROJECT-21K19531, KAKENHI-PROJECT-21K16424, KAKENHI-PROJECT-21K16451, KAKENHI-PROJECT-21K08779, KAKENHI-PROJECT-20K07678, KAKENHI-PROJECT-20K09057
  • [Presentation] Investigation of the mechanism of PSC activation and development of high-throughput drug screening detecting compounds targeting PSC2022

    • Author(s)
      Kohei Nakata, Toshiya Abe, Noboru Ideno, Naoki Ikenaga, Yusuke Mizuuchi, Kenoki Ohuchida, Masafumi Nakamura
    • Organizer
      第53回日本膵臓学会大会・第26回国際膵臓学会(IAP・JPS2022)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03754
  • [Presentation] 異なる薬物治療反応性を示す微小環境因子依存性に基づいた新たな膵癌サブタイプ分類2022

    • Author(s)
      新川智彦、大内田研宙、持田郁己、井手野昇、水内祐介、進藤幸治、池永直樹、森山大樹、仲田興平、中村雅史
    • Organizer
      第122回日本外科学会定期学術集会
    • Data Source
      KAKENHI-PROJECT-20H03530
  • [Presentation] Single cell RNA sequenceを用いた家族性大腸腺腫症におけるmacrophageのheterogeneityの解明2021

    • Author(s)
      久野恭子、水内祐介、大内田研宙、中村祥一、奥田翔、大坪慶志輝、佐田政史、永吉絹子、寅田信博、進藤幸治、仲田興平、森山大樹、永井俊太郎、中村雅史
    • Organizer
      第29回日本消化器関連学会週間(JDDW 2021)
    • Data Source
      KAKENHI-PROJECT-20K17621
  • [Presentation] scRNA-seqを用いたFAPにおける発癌過程の観察2021

    • Author(s)
      久野恭子、水内祐介、大内田研宙、中村祥一、奥田翔、大坪慶志輝、進藤幸治、仲田興平、森山大樹、永井俊太郎、中村雅史
    • Organizer
      第57回九州外科学会
    • Data Source
      KAKENHI-PROJECT-19K24016
  • 1.  進藤 幸治 (00788432)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 1 results
  • 2.  MIZUMOTO Kazuhiro (90253418)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 3.  堀岡 宏平 (10783699)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  KOZONO Shingo (40706850)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  木庭 遼 (10866776)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  久保 真 (60403961)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  宮坂 義浩 (40507795)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  大内田 研宙 (20452708)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 9.  仲田 興平 (30419569)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 10.  岩本 千佳 (10752842)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  藤田 逸人 (40611281)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  中山 宏道 (80866773)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  藤原 謙次 (10727184)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  安藤 陽平 (40746864)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  藤本 崇聡 (90891193)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  田村 公二 (90909582)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  池永 直樹 (90759755)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  佐田 政史 (10783508)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  永吉 絹子 (90761015)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  森山 大樹
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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