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Nohmi Takehiko  能美 健彦

… Alternative Names

NOUMI Takehiko  能美 健彦

NOHMI Takehiko  能美 健彦

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Researcher Number 30150890
Other IDs
  • ORCIDhttps://orcid.org/0000-0002-4729-6334
External Links
Affiliation (Current) 2025: 国立医薬品食品衛生研究所, 安全性生物試験研究センター, 客員研究員
Affiliation (based on the past Project Information) *help 2011 – 2018: 国立医薬品食品衛生研究所, 安全性生物試験研究センター, 客員研究員
2013: 独立行政法人医薬基盤研究所, 創薬支援戦略室, コーディネーター
2008 – 2011: National Institute of Health Sciences, 変異遺伝部, 部長
2003 – 2007: 国立医薬品食品衛生研究所, 変異遺伝部, 室長
2004: 国立医薬品食品衛生究所, 変異遺伝部, 室長 … More
2002: 国立医薬品食品研究所, 変異遺伝部, 室長
1999: Genetics and Mutagenesis, National Institute of Health Science, Chief investigator, 変異遺伝部, 主任研究員
1998 – 1999: 国立医薬品食品衛生研究所, 変異遺伝部, 室長(研究職)
1997 – 1998: 国立医薬品食品衛生研究所, 変異遺伝部, 室長
1996 – 1997: 国立衛生試験所, 変異遺伝部, 室長 Less
Review Section/Research Field
Principal Investigator
Risk sciences of radiation/Chemicals / Risk sciences of radiation and chemicals
Except Principal Investigator
Environmental pharmacy / Risk sciences of radiation and chemicals / Environmental pharmacy / Public health/Health science / 広領域 / Hygiene
Keywords
Principal Investigator
突然変異 / トランスリージョンDNA合成 / 閾値 / 環境変異原 / リスク評価 / DNAポリメラーゼ / DNAポリメラーゼ κ / ベンツピレン / DNAポリメラーゼ カッパ / 酸化DNA損傷 … More / 発がん / 遺伝毒性 / 炎症 / DNA損傷 / DNAポリメラーゼζ / 遺伝毒性発がん物質 / 癌 / 環境 / 遺伝子 / 有害化学物質 / 遺伝毒性の閾値 / トキシコロジー … More
Except Principal Investigator
benzo[a]pyrene / gpt deltaマウス / gpt delta mouse / ベンゾ[a]ピレン / Nrf2 / 変異原物質 / 遺伝子突然変異 / 多環芳香族炭化水素 / 遺伝子 / 突然変異 / トランスジェニックマウス遺伝子突然変異試験 / 生殖細胞突然変異 / 次世代シークエンサー / 環境変異原 / 次世代影響 / ゲノム / 遺伝毒性 / aging / Mutagen / 老化 / in vivo mutagenesis / transgenic mouse / nitropyrene / diesel exhaust / mutagen / Benzo(a)pyrene / 1,6-ジニトロピレン / 変異物質検出 / Nrf2ノックアウトマウス / 変異原物質検出 / 体内突然変異 / 遺伝子導入マウス / ニトロピレン / ディーゼル排気 / Nitroarene metabolic enzyme deficient strain / In vitro micronucleus test / Mouse lymphoma mutation assay (MLA) / Ame test / Genotoxicity / Polynulear Aromatic Hydrocarbon / Nitroarene / Urban airborne particulate / pSK1002菌株 / TA1535 / YG7126-7130株 / Ames-test / PAH / ニトロ還元酵素欠損株 / L5178Y細胞 / 7130株 / YG7126 / Ames test / ニトロアレーン代謝酵素欠損株 / in vitro小核試験 / マウスリンパ細胞試験 / エームステスト / 遺伝子毒性 / ニトロアレーン / 都市大気粉塵 / gene mutation / developmental toxicity / Embryonic stem cell / 突然変異検出系 / 分化 / 発生傷害 / 胚幹細胞 / DNAメチル基転移酵素 / 5-メチルシトシン / DNA損傷修復酵素 / Tet酵素 / グローバルDNAメチル化量 / 酸化的DNA損傷 / 低メチル食 / 能動的DNA脱メチル化 / 5ヒドロキシメチルシトシン / 5メチルシトシン / 能動的脱メチル化 / 無機ヒ素 / メチル欠乏食 / DNAメチル化 / エピジェネティクス / 酸化ストレス / 癌 / 有害化学物質 / 人間生活環境 / 環境質定量化・予測 / 点突然変異 / ディーゼルナノ粒子 / 経気道曝露 / In vivo mutation / 精巣 / 肺 / 体内変異原性 / 有害大気汚染物質 / 環境系薬学 / 遺伝病 / がん / 遺伝的不安定性 / 自然突然変異 / DNAポリメラーゼ / がん遺伝子 / DNA組換え / DNA / 酸素ラジカル / ノックアウトマウス / 繰り返し配列 / フレームシフト / DNA修復 / 酵素ラジカル / ミスマッチ修復 / 複製エラー / DNA複製 Less
  • Research Projects

    (11 results)
  • Research Products

    (201 results)
  • Co-Researchers

    (39 People)
  •  Roles of DNA polymerase kappa on establishment of threshold for genotoxic carcinogensPrincipal Investigator

    • Principal Investigator
      NOHMI TAKEHIKO
    • Project Period (FY)
      2014 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Risk sciences of radiation and chemicals
    • Research Institution
      National Institute of Health Sciences
  •  Studies on quantitative evaluation of inherited germline mutations

    • Principal Investigator
      Masumura Kenichi
    • Project Period (FY)
      2013 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Risk sciences of radiation and chemicals
    • Research Institution
      National Institute of Health Sciences
  •  Involvement of oxidative stress in the epigenetic changes induced by environmental chemicals

    • Principal Investigator
      NOHARA Keiko
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hygiene
    • Research Institution
      National Institute for Environmental Studies
  •  Studies on mechanisms underlying genotoxic thresholds through genetic modification of DNA polymerase zetaPrincipal Investigator

    • Principal Investigator
      NOHMI Takehiko
    • Project Period (FY)
      2010 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Risk sciences of radiation/Chemicals
    • Research Institution
      National Institute of Health Sciences
  •  Assessment of in vivo mutagenicity and trans-generational effect of compounds contained in suspended particulate matter in urban air

    • Principal Investigator
      AOKI Yasunobu
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Environmental pharmacy
    • Research Institution
      National Institute for Environmental Studies
  •  Studies on roles of translesion DNA synthesis in thresholds for genotoxic substancesPrincipal Investigator

    • Principal Investigator
      NOUMI Takehiko
    • Project Period (FY)
      2006 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Risk sciences of radiation/Chemicals
    • Research Institution
      National Institute of Health Sciences
  •  Quantitative estimation of susceptibility of aged animal to a mutagen in ambient air.

    • Principal Investigator
      AOKI Yasunobu
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Environmental pharmacy
    • Research Institution
      National Institute for Environmental Studies
  •  Sensitive detection of air-born mutagens and their evaluation using gene knockout mice

    • Principal Investigator
      AOKI Yasunobu
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Environmental pharmacy
    • Research Institution
      National Institute for Environmental Studies
  •  Genotoxicity of airborne particles from the urban area in Sapporo : Evaluation of the particulate samples collected over 22 year by bioassays

    • Principal Investigator
      SATOH Hiroshi
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Public health/Health science
    • Research Institution
      TOHOKU UNIVERSITY
  •  突然変異の分子病態

    • Principal Investigator
      真木 寿治
    • Project Period (FY)
      1996 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Nara Institute of Science and Technology
  •  Construction of mouse embryonic stem cells for the detection of gene mutation

    • Principal Investigator
      INOUE Tohru
    • Project Period (FY)
      1996 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      広領域
    • Research Institution
      National Institute of Health Sciences

All 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 Other

All Journal Article Presentation Book Patent

  • [Book] Thresholds of Genotoxic Carcinogens: from Mechanisms to Regulation2016

    • Author(s)
      T. Nohmi and T. Tsuzuki
    • Total Pages
      232
    • Publisher
      Elsevier
    • Data Source
      KAKENHI-PROJECT-26281029
  • [Book] Archaea:new models for prokaryotic biology2008

    • Author(s)
      T.Nohmi
    • Publisher
      Horizon Scientific Press
    • Data Source
      KAKENHI-PROJECT-18201010
  • [Book] DNA repair and DNA damage tolerance in archaeal bacteria: extreme environments and genome integrity, in Archaea: new models for prokaryotic biology2008

    • Author(s)
      T. Nohmi, M. Yamada, P. Gruz
    • Publisher
      Horizon Scientific Press.
    • Data Source
      KAKENHI-PROJECT-18201010
  • [Journal Article] DNA polymerase kappa counteracts inflammation-induced mutagenesis in multiple organs of mice2019

    • Author(s)
      A. Hakura, H. Sui, J. Sonoda, T. Matsuda and T. Nohmi
    • Journal Title

      Environ. Mol. Mutagen.

      Volume: 60 Issue: 4 Pages: 320-330

    • DOI

      10.1002/em.22272

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26281029
  • [Journal Article] Thresholds of genotoxic and non-genotoxic carcinogens2018

    • Author(s)
      T. Nohmi
    • Journal Title

      Toxicol. Res.

      Volume: 34 Issue: 4 Pages: 281-290

    • DOI

      10.5487/tr.2018.34.4.281

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26281029
  • [Journal Article] Impact of DNA polymerase ξ mutations on genotoxic thresholds of oxidative mutagens2018

    • Author(s)
      T. Suzuki, K. Matsumoto, M. Honma and T. Nohmi
    • Journal Title

      Mutat. Res.

      Volume: 828 Pages: 10-14

    • DOI

      10.1016/j.mrgentox.2018.02.001

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26281029
  • [Journal Article] Limited ability of DNA polymerase kappa to suppress benzo[a]pyrene-induced genotoxicity in vivo2017

    • Author(s)
      K. Masumura, N. Toyoda-Hokaiwado, N. Niimi, P. Gruz, N.A. Wada, A. Takeiri, K. Jishage, M. Mishima and T. Nohmi
    • Journal Title

      Environ. Mol. Mutagen.

      Volume: 58 Issue: 9 Pages: 644-653

    • DOI

      10.1002/em.22146

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26281029
  • [Journal Article] DNA polymerase kappa protects human cells against MMC-induced genotoxicity through error-free translesion DNA synthesis2017

    • Author(s)
      Y. Kanemaru, T. Suzuki, A. Sassa, K. Matsumoto, N. Adachi, M. Honma, S. Numazawa and T. Nohmi
    • Journal Title

      Genes and Environment

      Volume: 39 Issue: 1 Pages: 6-6

    • DOI

      10.1186/s41021-016-0067-3

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26281029, KAKENHI-PROJECT-15K07973, KAKENHI-PROJECT-16K16195
  • [Journal Article] Transgenic rat models for mutagenesis and carcinogenesis2017

    • Author(s)
      Nohmi T, Masumura K, Toyoda-Hokaiwado N.
    • Journal Title

      Genes and Environment

      Volume: 39 Issue: 1 Pages: 11-11

    • DOI

      10.1186/s41021-016-0072-6

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25281027, KAKENHI-PROJECT-26281029
  • [Journal Article] The role of DNA polymerase zeta in translesion synthesis across bulky DNA adducts and cross-links in human cells2016

    • Author(s)
      T. Suzuki, P. Gruz, M. Honma, N. Adachi and T. Nohmi
    • Journal Title

      Mutation Research

      Volume: 791-792 Pages: 35-41

    • DOI

      10.1016/j.mrfmmm.2016.08.004

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26281029, KAKENHI-PROJECT-25340044
  • [Journal Article] Dose-dependent de novo germline mutations detected by whole-exome sequencing in progeny of ENU-treated male gpt delta mice.2016

    • Author(s)
      Masumura K,Toyoda-Hokaiwado N, Ukai A, Gondo Y, Honma M, Nohmi T
    • Journal Title

      Mutation Research

      Volume: 810 Pages: 30-39

    • DOI

      10.1016/j.mrgentox.2016.09.009

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25241016, KAKENHI-PROJECT-25281027
  • [Journal Article] Sensitivity of human cells expressing low-fidelity or weak-catalytic-activity variants of DNA polymerase ξ to genotoxic stresses2016

    • Author(s)
      T. Suzuki, P. Gruz, M. Honma, N. Adachi and T. Nohmi
    • Journal Title

      DNA Repair

      Volume: 45 Pages: 34-43

    • DOI

      10.1016/j.dnarep.2016.06.002

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26281029, KAKENHI-PROJECT-25340044
  • [Journal Article] Estimation of the frequency of inherited germline mutations by whole exome sequencing in ethyl nitrosourea-treated and untreated gpt delta mice.2016

    • Author(s)
      Masumura K, Toyoda-Hokaiwado N, Ukai A, Gondo Y, Honma M, Nohmi T
    • Journal Title

      Genes and Environment

      Volume: 38 Issue: 1 Pages: 10-10

    • DOI

      10.1186/s41021-016-0035-y

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25241016, KAKENHI-PROJECT-25281027
  • [Journal Article] Past, Present and Future Directions of <i>gpt</i> delta Rodent Gene Mutation Assays2016

    • Author(s)
      T. Nohmi
    • Journal Title

      Food Safety

      Volume: 4 Issue: 1 Pages: 1-13

    • DOI

      10.14252/foodsafetyfscj.2015024

    • NAID

      130005142911

    • ISSN
      2187-8404
    • Language
      English
    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26281029
  • [Journal Article] Alterations in the mutagenicity and mutation spectrum induced by benzo[a]pyrene instilled in the lungs of gpt delta mice of various ages2015

    • Author(s)
      Aoki Y, Akiko A, Sugawara Y, Hiyoshi-Arai K, Goto S, Masumura K, Nohmi T.
    • Journal Title

      Genes and Environment

      Volume: 37 Issue: 1 Pages: 7-7

    • DOI

      10.1186/s41021-015-0004-x

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25281027, KAKENHI-PROJECT-25293034
  • [Journal Article] Genomic integration of lambda EG10 transgene in gpt delta transgenic rodents2015

    • Author(s)
      Masumura K, Sakamoto Y, Kumita W, Honma M, Nishikawa A, Nohmi T.
    • Journal Title

      Genes and Environment

      Volume: 37 Issue: 1 Pages: 24-24

    • DOI

      10.1186/s41021-015-0024-6

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25281027, KAKENHI-PROJECT-25293034, KAKENHI-PROJECT-26281029
  • [Journal Article] Catalytic and non-catalytic roles of DNA polymerase κ in the protection of human cells against genotoxic stresses2015

    • Author(s)
      Kanemaru Y, Suzuki T, Niimi N, Gruze P, Matsumoto K, Adachi N, Honma M, Nohmi T
    • Journal Title

      Environmental Moleculer Mutagenesis

      Volume: 56 Issue: 8 Pages: 650-662

    • DOI

      10.1002/em.21961

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25340044, KAKENHI-PROJECT-26281029
  • [Journal Article] Role of p53 in the progression from ochratoxin A-induced DNA damage to gene mutations in the kidneys of mice.2015

    • Author(s)
      Kuroda K, Hibi D, Ishii Y, Yokoo Y, Takasu S, Kijima A, Matsushita K, Masumura K, Kodama Y, Yanai T, Sakai H, Nohmi T, Ogawa K, Umemura T.
    • Journal Title

      Toxicol Sci.

      Volume: 144 Issue: 1 Pages: 65-76

    • DOI

      10.1093/toxsci/kfu267

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25281027
  • [Journal Article] Genotoxicity of phenacetin in the kidney and liver of Sprague-Dawley gpt delta transgenic rats in 26-week and 52-week repeated-dose studies.2014

    • Author(s)
      Kawamura Y, Hayashi H, Masumura K, Numazawa S, Nohmi T.
    • Journal Title

      Toxicology

      Volume: 324 Pages: 10-17

    • DOI

      10.1016/j.tox.2014.07.003

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25281027, KAKENHI-PROJECT-25293034
  • [Journal Article] Combined application of comprehensive analysis for DNA modification and reporter gene mutation assay to evaluate kidneys of gpt delta rats given madder color or its constituents2014

    • Author(s)
      Y. Ishii, S. Takasu, K. Kuroda, K. Matsushita, A. Kijima, T. Nohmi, K. Ogawa and T. Umemura
    • Journal Title

      Anal.Bioanal.Chem.

      Volume: 406 Issue: 9-10 Pages: 2467-2475

    • DOI

      10.1007/s00216-014-7621-2

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22241016
  • [Journal Article] in vivo evidence that DNA polymerase kappa is responsible for error-free bypass across DNA cross-links induced by mitomycin C2014

    • Author(s)
      A. Takeiri, N.A. Wada, S. Motoyama, K. Matsuzaki, H. Tateishi, K. Matsumoto, N. Niimi, A. Sassa, P. Gruz, K. Masumura, M. Yamada, M. Mishima, K.I. Jishage and T. Nohmi,
    • Journal Title

      DNA Repair

      Volume: 24 Pages: 113-121

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26281029
  • [Journal Article] in vivo evidence that phenylalanine 171 acts as a molecular brake for translesion DNA synthesis across benzo[a]pyrene DNA adducts by human DNA polymerase2014

    • Author(s)
      A. Sassa, T. Suzuki, Y. Kanemaru, N. Niimi, H. Fujimoto, A. Katafuchi, P. Gruz, M. Yasui, R.C. Gupta, F. Johnson, T. Ohta, M. Honma, N. Adachi and T. Nohmi
    • Journal Title

      DNA Repair

      Volume: 15 Pages: 21-28

    • DOI

      10.1016/j.dnarep.2013.12.008

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22241016, KAKENHI-PROJECT-24659035, KAKENHI-PROJECT-25281022, KAKENHI-PROJECT-25340044
  • [Journal Article] Ochratoxin A induces DNA double-strand breaks and large deletion mutations in the carcinogenic target site of gpt delta rats2014

    • Author(s)
      K. Kuroda, D. Hibi, Y. Ishii, S. Takasu, A. Kijima, K. Matsushita, K. Masumura, M. Watanabe, Y. Sugita-Konishi, H. Sakai, T. Yanai, T. Nohmi, K. Ogawa and T. Umemura
    • Journal Title

      Mutagenesis

      Volume: 29 Issue: 1 Pages: 27-36

    • DOI

      10.1093/mutage/get054

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22241016, KAKENHI-PROJECT-25281027
  • [Journal Article] In vivo evidence that DNA polymerase kappa is responsible for error-free bypass across DNA cross-links induced by mitomycin C.2014

    • Author(s)
      Takeiri A, Wada NA, Motoyama S, Matsuzaki K, Tateishi H, Matsumoto K, Niimi N, Sassa A, Grúz P, Masumura K, Yamada M, Mishima M, Jishage KI, Nohmi T.
    • Journal Title

      DNA Repair

      Volume: 24 Pages: 113-121

    • DOI

      10.1016/j.dnarep.2014.09.002

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25281027, KAKENHI-PROJECT-25293034
  • [Journal Article] in vivo mutagenicity of arsenite in the livers of gpt delta transgenic mice2014

    • Author(s)
      S. Takumi, Y. Aoki, T. Sano, T. Suzuki, T. Nohmi and K. Nohara
    • Journal Title

      Mutat. Res.

      Volume: 760 Pages: 42-47

    • DOI

      10.1016/j.mrgentox.2013.12.001

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22241016, KAKENHI-PROJECT-23390166, KAKENHI-PROJECT-24790600, KAKENHI-PROJECT-25293034, KAKENHI-PROJECT-25460831
  • [Journal Article] Evaluation of in vivo genotoxicity induced by N-ethyl-N-nitrosourea, benzo[a]pyrene, and 4-nitroquinoline-1-oxide in the Pig-a and gpt assays2013

    • Author(s)
      K. Horibata, A. Ukai, T. Kimoto, T. Suzuki, N. Kamoshita, K. Masumura, T. Nohmi and M. Honma
    • Journal Title

      Environ. Mol. Mutagen.

      Volume: 54 Issue: 9 Pages: 747-754

    • DOI

      10.1002/em.21818

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22241016, KAKENHI-PROJECT-25281027
  • [Journal Article] Evaluation of the genotoxicity of tamoxifen in the liver and kidney of F344 gpt delta transgenic rat in 3-week and 13-week repeated dose studies2013

    • Author(s)
      Y. Kawamura, H. Hayashi, Y. Kurata, K. Hirasuka, K. Masumura and T. Nohmi
    • Journal Title

      Toxicol.

      Volume: 312 Pages: 56-62

    • DOI

      10.1016/j.tox.2013.07.014

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22241016, KAKENHI-PROJECT-25281027
  • [Journal Article] DNA polymerase kappa-dependent DNA synthesis at stalled replication forks is important for CHK1 activation2013

    • Author(s)
      R. Betous, M.J. Pillaire, L. Pierini, S. van der Laan, B. Recolin, E. Ohl-Seguy, C. Guo, N. Niimi, P. Gruz, T. Nohmi, E. Friedberg, C. Cazaux, D. Maiorano and J.S. Hoffmann
    • Journal Title

      EMBO J.

      Volume: 32 Issue: 15 Pages: 2172-2185

    • DOI

      10.1038/emboj.2013.148

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22241016
  • [Journal Article] Development of a Medium-term Animal Model Using <i>gpt</i> Delta Rats to Evaluate Chemical Carcinogenicity and Genotoxicity2013

    • Author(s)
      K. Matsushita, A. Kijima, Y. Ishii, S.Takasu, M. Jin, K. Kuroda, H. Kawaguchi, N. Miyoshi, T. Nohmi, K. Ogawa and T. Umemura
    • Journal Title

      Journal of Toxicologic Pathology

      Volume: 26 Issue: 1 Pages: 19-27

    • DOI

      10.1293/tox.26.19

    • NAID

      130003362353

    • ISSN
      0914-9198, 1881-915X
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22241016
  • [Journal Article] Cell cycle progression, but not genotoxic activity, mainly contributes to citrinin-induced renal carcinogenesis2013

    • Author(s)
      K. Kuroda, Y. Ishii, S. Takasu, A. Kijima, K. Matsushita, M. Watanabe, H. Takahashi, Y. Sugita-Konishi, H. Sakai, T. Yanai, T. Nohmi, K. Ogawa and T. Umemura
    • Journal Title

      Toxicol.

      Volume: 311 Issue: 3 Pages: 216-224

    • DOI

      10.1016/j.tox.2013.07.003

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22241016
  • [Journal Article] Restoration of mismatch repair functions in human cell line Nalm-6, which has high efficiency for gene targeting2013

    • Author(s)
      T. Suzuki, A. Ukai, M. Honma, N. Adachi and T. Nohmi
    • Journal Title

      PLoS.One

      Volume: 8 Issue: 4 Pages: e61189-e61189

    • DOI

      10.1371/journal.pone.0061189

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22241016, KAKENHI-PROJECT-24659035
  • [Journal Article] 2nd International Symposium on Genotoxic and Carcinogenic Thresholds2012

    • Author(s)
      T. Nohmi, M. Honma, M. Yamada, K. Masumura, M. Yasui, K. Horibata and S. Fukushima
    • Journal Title

      Genes and Environment

      Volume: 34 Issue: 4 Pages: 141-145

    • DOI

      10.3123/jemsge.34.141

    • NAID

      10031125861

    • ISSN
      1880-7046, 1880-7062
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22241016
  • [Journal Article] <i>in vivo</i> Approaches to Identify Mutations and <i>in vitro</i> Research to Reveal Underlying Mechanisms of Genotoxic Thresholds2012

    • Author(s)
      T. Nohmi, M. Yamada and K. Masumura
    • Journal Title

      Genes and Environment

      Volume: 34 Issue: 4 Pages: 146-152

    • DOI

      10.3123/jemsge.34.146

    • NAID

      10031125862

    • ISSN
      1880-7046, 1880-7062
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22241016
  • [Journal Article] Evaluation of <i>In Vivo</i> Mutagenicity by 2,4-Diaminotoluene and 2,6-Diaminotoluene in Liver of F344 <i>gpt</i> delta Transgenic Rat Dosed for 28 Days: A Collaborative Study of the <i>gpt</i> delta Transgenic Rat Mutation Assay2012

    • Author(s)
      Sui H, Ohta R, Shiragiku T, Akahori A, Suzuki K, Nakajima M, Hayashi H, Masumura K, Nohmi T
    • Journal Title

      Genes and Environment

      Volume: 34 Issue: 1 Pages: 25-33

    • DOI

      10.3123/jemsge.34.25

    • NAID

      130004481193

    • ISSN
      1880-7046, 1880-7062
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390038
  • [Journal Article] Escherichia coli DNA polymerase III is responsible for the high level of spontaneous mutations in mutT strains2012

    • Author(s)
      M. Yamada, M. Shimizu, A. Katafuchi, P. Gruz, S. Fujii, Y. Usui, R.P. Fuchs and T. Nohmi
    • Journal Title

      Mol. Microbiol.

      Volume: 86 Issue: 6 Pages: 1364-1375

    • DOI

      10.1111/mmi.12061

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22241016
  • [Journal Article] Evaluation of the in vivo Mutagenicity of Nickel Subsulfide in the Lung of F344 gpt delta Transgenic Rats Exposed by Intratracheal Instillation: A Collaborative Study for the gpt delta Transgenic Rat Mutation Assay2012

    • Author(s)
      Kamigaito T, Noguchi T, Narumi K, Takashima R, Hamada S, Sanada H, Hasuko M, Hayashi H, Masumura K, Nohmi T
    • Journal Title

      Genes and Environment

      Volume: 34 Issue: 1 Pages: 34-44

    • DOI

      10.3123/jemsge.34.34

    • NAID

      130004481194

    • ISSN
      1880-7046, 1880-7062
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390038
  • [Journal Article] Phenylalanine 171 is a molecular brake for translesion synthesis across benzo[a]pyrene-guanine adducts by human DNA polymerase kappa2011

    • Author(s)
      A. Sassa, N. Niimi, H. Fujimoto, A. Katafuchi, P. Gruz, M. Yasui, R. C. Gupta, F. Johnson, T. Ohta and T. Nohmi
    • Journal Title

      Mutat. Res.

      Volume: 718 Issue: 1-2 Pages: 10-17

    • DOI

      10.1016/j.mrgentox.2010.11.002

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22241016, KAKENHI-PROJECT-22710068
  • [Journal Article] Evaluation of in vivo mutagenicity by 2, 4-diaminotoluene and 2, 6-diaminotoluene in liver of F344 gpt delta transgenic rat dosed for 28 days : a collaborative study of the gpt delta transgenic rat mutation assay2011

    • Author(s)
      Sui H, Ohta R, Shiragiku T, Akahori A, Suzuki K, Nakajima M, Hayashi H, Masumura K, Nohmi T
    • Journal Title

      Genes Environ

      Volume: 34 Pages: 25-33

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390038
  • [Journal Article] Evaluation of the in vivo mutagenicity of nickel subsulfide in the lung of F344 gpt delta transgenic rats exposed by intratracheal instillation : A collaborative study for the gpt delta transgenic rat mutation assay2011

    • Author(s)
      Kamigaito T, Noguchi T, Narumi K, Takashima R, Hamada S, Sanada H, Hasuko M, Hayashi H, Masumura K, Nohmi T
    • Journal Title

      Genes En viron

      Volume: 34 Pages: 34-44

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390038
  • [Journal Article] Critical amino acids in human DNA polymerasesηandκinvolved in erroneous incorporation of oxidized nucleotides2010

    • Author(s)
      A. Katafuchi, A. Sassa, N. Niimi, P. Gruz, H. Fujimoto, C. Masutani, F. Hanaoka, T. Ohta, T. Nohmi
    • Journal Title

      Nucleic Acids Res. 38

      Pages: 859-867

    • Data Source
      KAKENHI-PROJECT-18201010
  • [Journal Article] Integration of in vivo genotoxicity and short-term carcinogenicity assays using F344 gpt delta transgenic rats : in vivo mutagenicity of 2,4-diaminotoluene and 2,6-diaminotoluene structural isomers2010

    • Author(s)
      N Toyoda-Hokaiwado, T. Inoue, K. Masumura, H. Hayashi, Y. Kawamura, Y. Kurata, M. Takamune, M. Yamada, H. Sanada, T. Umemura, A. Nishikawa and T. Nohmi
    • Journal Title

      Toxicol. Sci.

      Volume: 114 Issue: 1 Pages: 71-78

    • DOI

      10.1093/toxsci/kfp306

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22241016
  • [Journal Article] Nucleotide pool damage and its biological consequences2010

    • Author(s)
      T.Nohmi
    • Journal Title

      Mutat.Res.

      Volume: 703 Pages: 1-1

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22241016
  • [Journal Article] The steric gate amino acid tyrosine 112 is required for efficient2009

    • Author(s)
      N. Niim, A. Sassa, A. Katafuchi, P. Gruz, H. Fujimoto, R.R. Bonala, F. Johnson, T. Ohta, and T. Nohmi
    • Journal Title

      mismatched-primer extension by human DNA polymerase k, Biochem 48

      Pages: 4329-4246

    • Data Source
      KAKENHI-PROJECT-18201010
  • [Journal Article] Possible mechanisms of practical thresholds for genotoxicity2009

    • Author(s)
      T. Nohmi
    • Journal Title

      Genes and Environment 30

      Pages: 108-113

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18201010
  • [Journal Article] International symposium on genotoxic and carcinogenic thresholds2009

    • Author(s)
      T. Nohmi
    • Journal Title

      Genes and Environment 30

      Pages: 101-107

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18201010
  • [Journal Article] Spontaneous mutagenesis in rodents : spontaneous gene mutations identified by neutral reporter genes in gpt delta transgenic mice and rats2009

    • Author(s)
      K. Masumura, T. Nohmi
    • Journal Title

      J. Health Sci 55

      Pages: 40-49

    • NAID

      110007055908

    • Data Source
      KAKENHI-PROJECT-18201010
  • [Journal Article] The steric gate amino acid tyrosine 112 is required for efficient mismatched-primer extension by human DNA polymeraseκ2009

    • Author(s)
      N. Niimi, A. Sassa, A. Katafuchi, P. Gruz, H. Fujimoto, R.R. Bonala, F. Johnson, T. Ohta, T. Nohmi
    • Journal Title

      Biochem. 48

      Pages: 4239-4246

    • Data Source
      KAKENHI-PROJECT-18201010
  • [Journal Article] Spontaneous mutagenesis in rodents: spontaneous gene mutations identified by neutral reporter genes in gpt delta transgenic mice and rats2009

    • Author(s)
      K. Masumura, T. Nohmi
    • Journal Title

      J. Health Sci. 55

      Pages: 40-49

    • NAID

      110007055908

    • Data Source
      KAKENHI-PROJECT-18201010
  • [Journal Article] Specificity of mutations induced by incorporation of oxidized dNTPs into DNA by human DNA polymeraseη2008

    • Author(s)
      K. Hidaka, M. Yamada, H. Kamiya, C. Masutani, H. Harashima, F. Hanaoka, T. Nohmi
    • Journal Title

      DNA Repair 7

      Pages: 497-506

    • Data Source
      KAKENHI-PROJECT-18201010
  • [Journal Article] International symposium on genotoxic and carcinogenic thresholds2008

    • Author(s)
      T. Nohmi, N. Toyoda-Hokaiwado, M. Yamada, K. Masumura, M. Honma, S. Fukushima
    • Journal Title

      Genes and Environ. 30

      Pages: 101-107

    • NAID

      110007007982

    • Data Source
      KAKENHI-PROJECT-18201010
  • [Journal Article] Possible mechanisms of practical thresholds for genotoxicity2008

    • Author(s)
      T. Nohmi
    • Journal Title

      Genes and Environ. 30

      Pages: 108-113

    • Data Source
      KAKENHI-PROJECT-18201010
  • [Journal Article] Possible mechanisms of practical thresholds for genotoxicity2008

    • Author(s)
      T. Nohmi
    • Journal Title

      Genes and Environ 30

      Pages: 108-113

    • Data Source
      KAKENHI-PROJECT-18201010
  • [Journal Article] Efficient and erroneous incorporation of oxidized DNA precursors by human DNA polymeraseη2007

    • Author(s)
      M. Shimizu, P. Gruz, H. Kamiya, C. Masutani, Y. Xu, Y. Usui, H. Sugiyama, H. Harashima, F. Hanaoka, T. Nohmi
    • Journal Title

      Biochem. 46

      Pages: 5515-5522

    • Data Source
      KAKENHI-PROJECT-18201010
  • [Journal Article] Novel DNA polymerases and novel genotoxicity assays2007

    • Author(s)
      T.Nohmi
    • Journal Title

      Genes and ENviron. 29

      Pages: 75-88

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18201010
  • [Journal Article] Novel DNA polymerases and novel genotoxicity assays2007

    • Author(s)
      T. Nohmi
    • Journal Title

      Genes and Environ. 29

      Pages: 75-88

    • Data Source
      KAKENHI-PROJECT-18201010
  • [Journal Article] Enhanced spontaneous and benzo(a)pyrene-induced mutations in the lung of Nrf2-deficient gpt delta mice2007

    • Author(s)
      Y. Aoki, A.H. Hashimoto, K. Akanuma, M. Matsumoto, K. Hiyoshi, H. Takano, K. Masumura, K. Itoh, T. Nohmi, M. Yamamoto
    • Journal Title

      Cancer Res. 67

      Pages: 5643-5648

    • Data Source
      KAKENHI-PROJECT-18201010
  • [Journal Article] Involvement of Y-family DNA polymerases in mutagenesis caused by oxidized nucleotides in Escherichia coli2006

    • Author(s)
      M. Yamada, T. Nunoshiba, M. Shimizu, P. Gruz, H. Kamiya, H. Harashima, T. Nohmi
    • Journal Title

      J. Bacteriol. 188

      Pages: 4992-4995

    • Data Source
      KAKENHI-PROJECT-18201010
  • [Journal Article] Specificity of replicative and SOS-inducible DNA polymerases in frameshift mutagenesis: Mutability of Salmonella typhimurium strains overexpressing SOS-inducible DNA polymerases to 30 chemical mutagens2006

    • Author(s)
      K. Matsui, M. Yamada, M. Imai, K. Yamamoto, T. Nohmi
    • Journal Title

      DNA Repair 5

      Pages: 465-478

    • Data Source
      KAKENHI-PROJECT-18201010
  • [Journal Article] Environmental stress and lesion-bypass DNA polymerases2006

    • Author(s)
      T. Nohmi
    • Journal Title

      Ann. Rev. Microbiol 60

      Pages: 231-253

    • Data Source
      KAKENHI-PROJECT-18201010
  • [Journal Article] Environmental stress and lesion-bypass DNA polymerases2006

    • Author(s)
      T.Nohmi
    • Journal Title

      Ann. Rev. Microbiol. 60

      Pages: 231-253

    • Data Source
      KAKENHI-PROJECT-18201010
  • [Journal Article] Environmental stress and lesion-bypass DNA polymerases2006

    • Author(s)
      T. Nohmi
    • Journal Title

      Ann. Rev. Microbiol. 60

      Pages: 231-253

    • Data Source
      KAKENHI-PROJECT-18201010
  • [Journal Article] In Vivo Mutagenesis Induced by Benzo[a]pyrene Instilled Into the Lung of gpt delta Transgenic Mice2005

    • Author(s)
      A.Hashimoto, K.Amanuma, K.Hiyoshi, H.Takano, K.Masumura, T.Nohmi, Y.Aoki
    • Journal Title

      Environmental and Molecular Mutagenesis Vol.45

      Pages: 365-373

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14207100
  • [Journal Article] Dynamic Bypass of a Major Cisplatin-DNA Adduct Revealed in Structural, Kinetic and in vivo Studies

    • Author(s)
      J.H.Y. Wong, J.A. Brown, Z. Suo, P. Blum, T. Nohmi, H. Ling
    • Journal Title

      EMBO J. (in press)

    • Data Source
      KAKENHI-PROJECT-18201010
  • [Journal Article] DNA polymeraseds involved in the incorporation of oxidized nucleotides into DNA: the efficiency and template base preference

    • Author(s)
      A. Katafuchi, T. Nohmi
    • Journal Title

      Mutat. Res. (in press)

    • Data Source
      KAKENHI-PROJECT-18201010
  • [Patent] 突然変異検出用トランスジェニックラットとその作製方法およびそれを用いた突然変異試験法2006

    • Inventor(s)
      能美健彦, 増村健一, 神藤康弘, 林 宏行
    • Industrial Property Rights Holder
      国立医薬品食品衛生研究所長
    • Acquisition Date
      2006-05-12
    • Data Source
      KAKENHI-PROJECT-18201010
  • [Patent] 突然変異検出用トランスジェニックラットとその作製方法およびそれを用いた突然変異試験法2006

    • Inventor(s)
      能美健彦、増村健一、神藤康弘、林宏行
    • Industrial Property Rights Holder
      国立医薬品食品衛生研究所長
    • Filing Date
      2006-05-12
    • Acquisition Date
      2006-05-12
    • Data Source
      KAKENHI-PROJECT-18201010
  • [Presentation] gpt deltaラット:突然変異、発がん研究のためのトランスジェニックラット2019

    • Author(s)
      能美健彦
    • Organizer
      第12回ラットリソースリサーチ研究会
    • Invited
    • Data Source
      KAKENHI-PROJECT-26281029
  • [Presentation] Risk assessment of genotoxic and non-genotoxic carcinogens2017

    • Author(s)
      T. Nohmi
    • Organizer
      The 12th International Conference and 5th Asian Congress on Environmental Mutagens
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26281029
  • [Presentation] Introduction: Experimental approaches to investigate the constitutents of genotoxic and carcinogenic thresholds2017

    • Author(s)
      T. Nohmi
    • Organizer
      The 12th International Conference and 5th Asian Congress on Environmental Mutagens
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26281029
  • [Presentation] Knock-in and knockout strategies to analyze in vivo protective roles of specialized DNA polymerases2017

    • Author(s)
      T. Nohmi
    • Organizer
      6th US-Japan DNA repair meeting
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26281029
  • [Presentation] 遺伝毒性物質とは何か?:DNAと反応する遺伝毒性物質、DNAと反応しない遺伝毒性物質2017

    • Author(s)
      能美健彦
    • Organizer
      第44回日本毒性学会学術年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-26281029
  • [Presentation] 突然変異の誘発と抑制に関わるトランスリージョンDNAポリメラーゼ2016

    • Author(s)
      能美健彦
    • Organizer
      平成28年度 第2回環境科学専攻 月例セミナー
    • Place of Presentation
      静岡県立大、静岡県
    • Invited
    • Data Source
      KAKENHI-PROJECT-26281029
  • [Presentation] Translesion DNA synthesis: it implication in toxicology2016

    • Author(s)
      T. Nohmi
    • Organizer
      2016 KSOT/KEMS Spring International Symposium
    • Place of Presentation
      Chungbuk University, Korea
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26281029
  • [Presentation] Analysis of inherited germline mutations of ENU-treated mice by whole exome sequencing2016

    • Author(s)
      Masumura K, Toyoda-Hokaiwado N, Ukai A, Gondo Y, Honma M, Nohmi T
    • Organizer
      Society of Toxicology 55th Annual meeting
    • Place of Presentation
      New Orleans Ernest N. Morial Convention Center, LA, USA
    • Year and Date
      2016-03-13
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25281027
  • [Presentation] Benzo[a][pyreneによるマウス肺の突然変異誘発におけるDNA Polymerase ξ の役割2016

    • Author(s)
      石井雄二、高須伸二、木島綾希、能美健彦、小川久美子、梅村隆志
    • Organizer
      日本環境変異原学会第45回大会
    • Place of Presentation
      エポカルつくば、茨城県
    • Year and Date
      2016-11-17
    • Data Source
      KAKENHI-PROJECT-26281029
  • [Presentation] DNA中の酸化リボヌクレオチドにおける損傷乗り越えDNA合成と修復2016

    • Author(s)
      佐々彰、Melike Caglayan、William A. Beard, Samuel H. Wilson, 能美健彦、本間正充、安井学
    • Organizer
      第39回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜、神奈川県
    • Year and Date
      2016-11-30
    • Data Source
      KAKENHI-PROJECT-26281029
  • [Presentation] Estimation of the frequency of inherited germline mujtations by whole-exome sequencing in ethylnitrosourea-treated gpt delta mice2016

    • Author(s)
      Masumura K, Toyoda-Hokaiwado N, Ukai A, Gondo Y, Honma M, Nohmi T
    • Organizer
      47th Annual Meeting of Environmental Mutagenesis and Genomics Society
    • Place of Presentation
      Westin Kansas City at Crown center
    • Year and Date
      2016-09-24
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25281027
  • [Presentation] 全エキソーム解析を用いたENU 投与雄マウスの次世代個体における生殖細胞系列突然変異頻度の測定2016

    • Author(s)
      増村健一,鵜飼明子,豊田尚美,権藤洋一,能美健彦,本間正充
    • Organizer
      日本環境変異原学会第45回大会
    • Place of Presentation
      つくば国際会議場
    • Year and Date
      2016-11-17
    • Data Source
      KAKENHI-PROJECT-25281027
  • [Presentation] げっ歯類を用いた遺伝子突然変異試験法の開発2015

    • Author(s)
      能美健彦
    • Organizer
      日本環境変異原学会第44回大会
    • Place of Presentation
      九州大学(福岡県)
    • Year and Date
      2015-11-27
    • Invited
    • Data Source
      KAKENHI-PROJECT-26281029
  • [Presentation] DNA polymerase kappaはin vivoにおいて、cisplatinに対する損傷乗越えDNA複製に関与する2015

    • Author(s)
      本山茂記、竹入章、松尾沙織里、和田直子、寺社下浩一、三島雅之、新見直子、Petr Gruz、増村健一、山田雅巳、能美健彦
    • Organizer
      日本環境変異原学会第44回大会
    • Place of Presentation
      九州大学馬出キャンパス
    • Year and Date
      2015-11-27
    • Data Source
      KAKENHI-PROJECT-25281027
  • [Presentation] DNA polymerase kappaはin vivoにおいて、cisplatinに対する損傷乗り越えDNA複製に関与する2015

    • Author(s)
      本山茂記、竹入章、松尾沙織里、松田直子、寺社下浩一、三島雅之、新見直子、Petr Gruz、増村健一、山田雅巳、能美健彦
    • Organizer
      日本環境変異原学会第44回大会
    • Place of Presentation
      九州大学(福岡県)
    • Year and Date
      2015-11-27
    • Data Source
      KAKENHI-PROJECT-26281029
  • [Presentation] Catalytic and structural roles of DNA polymerase κ in genome integrity of human cells2015

    • Author(s)
      Y. Kanemaru, T. Suzuki, N. Niimi, P. Gr&#250;z, K. Matsumoto, N. Adachi, M. Honma and T. Nohmi
    • Organizer
      Genomic Integrity Conference 2015
    • Place of Presentation
      Cairns, Australia
    • Year and Date
      2015-08-01
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26281029
  • [Presentation] Sensitivity of inactivated DNA polymerase kappa knock-in mice to mitomycin C2015

    • Author(s)
      A. Takeiri, N.A. Wada, S. Motoyama, K. Matsuzaki, H. Tateishi, K. Matsumoto, N. Niimi, A. Sassa, P. Gr&#250;z, K. Masumura, M. Yamada, M. Mishima, K. Jishage and T. Nohmi
    • Organizer
      The 7th International Congress of Asian Society of Toxicology
    • Place of Presentation
      Jeju, Korea
    • Year and Date
      2015-06-23
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26281029
  • [Presentation] 生殖細胞におけるDNA損傷と突然変異2015

    • Author(s)
      能美健彦
    • Organizer
      日本進化学会第17回大会
    • Place of Presentation
      中央大学理工学部(東京)
    • Year and Date
      2015-08-20
    • Invited
    • Data Source
      KAKENHI-PROJECT-26281029
  • [Presentation] マウス全エキソーム解析によるENU誘発生殖細胞変異スペクトルの解析2015

    • Author(s)
      増村健一、鵜飼明子、豊田尚美、権藤洋一、能美健彦、本間正充
    • Organizer
      日本環境変異原学会第44回大会
    • Place of Presentation
      九州大学馬出キャンパス
    • Year and Date
      2015-11-27
    • Data Source
      KAKENHI-PROJECT-25281027
  • [Presentation] 都市大気浮粒子抽出物がgpt deltaマウス肺で示す変異原性と突然変異スペクトル2015

    • Author(s)
      青木康展、中島大介、松本みちよ、松本理、柳澤利枝、後藤純雄、増村健一、能美健彦
    • Organizer
      日本環境変異原学会第44回大会
    • Place of Presentation
      九州大学馬出キャンパス
    • Year and Date
      2015-11-27
    • Data Source
      KAKENHI-PROJECT-25281027
  • [Presentation] Protective roles of DNA polymerase ξ in human cells against environmental genotoxins2015

    • Author(s)
      T. Suzuki, P. Gr&#250;z, M. Honma, N. Adachi and T. Nohmi
    • Organizer
      Environmental Mutagenesis and Genomics Society, the 46th Annual Meeting
    • Place of Presentation
      New Orleans, U.S.A.
    • Year and Date
      2015-09-26
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26281029
  • [Presentation] Sensitivity of inactivated DNA polymerase kappa knock-in mice to mitomycin C2015

    • Author(s)
      Takeiri A, Naoko AW, Motoyama S, Matsuzaki K, Tateishi H, Matsumoto K, Niimi N, Sassa A, Gr&uacute;z P, Masumura K, Yamada M, Mishima M, Jishage K, Nohmi T
    • Organizer
      The 7th International Congress of Asian Society of Toxicology
    • Place of Presentation
      International Convention Center Jeju Island, South Korea
    • Year and Date
      2015-06-23
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25281027
  • [Presentation] Germ cell and somatic cell mutagenesis in gpt delta rodents2014

    • Author(s)
      T. Nohmi
    • Organizer
      International Symposium on Germline Mutagenesis and Biodiversity
    • Place of Presentation
      Fukuoka, Japan
    • Data Source
      KAKENHI-PROJECT-22241016
  • [Presentation] In vivo mutagenicity assay of arsenite using gpt delta transgenic mice, Society of Toxicology2014

    • Author(s)
      Takumi S, Aoki Y, Sano T, Suzuki T, Nohmi T, and Nohara K
    • Organizer
      53rd Annual Meeting
    • Place of Presentation
      Phoenix, USA
    • Year and Date
      2014-03-26
    • Data Source
      KAKENHI-PROJECT-23390166
  • [Presentation] gpt deltaラットを用いた中期発がん評価系の開発2013

    • Author(s)
      松下幸平,黑田顕,石井雄二,高須伸二,木島綾希,能美健彦,小川久美子,梅村隆志
    • Organizer
      日本環境変異原学会第42回大会
    • Place of Presentation
      岡山
    • Data Source
      KAKENHI-PROJECT-22241016
  • [Presentation] Partial restration of UV-mutagenesis in a umuDC-deletion mutant of Escherichia coli with human DNA polymerase eta2013

    • Author(s)
      P. Gruz and T. Nohmi
    • Organizer
      日本環境変異原学会第42回大会
    • Place of Presentation
      岡山
    • Data Source
      KAKENHI-PROJECT-22241016
  • [Presentation] DNA repair and translesion DNA synthesis as constituents of "threshold" of genotoxicity2013

    • Author(s)
      T. Nohmi, T. Suzuki, K. Matsumoto and M. Honma
    • Organizer
      The XIII International Congress of Toxicology
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2013-07-03
    • Data Source
      KAKENHI-PROJECT-22241016
  • [Presentation] gpt deltaマウスを用いたENU誘発突然変異と全エクソンシークエンスによる経世代変異の検出2013

    • Author(s)
      増村健一,豊田尚美,権藤洋一,能美健彦,本間正充
    • Organizer
      日本環境変異原学会第42回大会
    • Place of Presentation
      岡山コンベンションセンター(岡山県岡山市)
    • Data Source
      KAKENHI-PROJECT-25281027
  • [Presentation] Phenylalanine 171 of human DNA polymerase kappa is a molecular brake for translesion DNA synthesis across benzo[a]pyrene adducts2013

    • Author(s)
      A.Sassa, T. Suzuki, Y. Kanemaru, N. Niimi, H. Fujimoto, A. Katafuchi, P. Gruz, M. Yasui, R. C. Gupta, F. Johnson, T. Ohta, M. Honma, N. Adachi and T. Nohmi
    • Organizer
      44th Environmental Mutagenesis and Genomics Society
    • Place of Presentation
      Monterey, California, U.S.A.
    • Data Source
      KAKENHI-PROJECT-22241016
  • [Presentation] 臭素酸カリウムがgpt deltaマウス小腸で誘導する突然変異の閾値と変異スペクトルの用量依存性変化2013

    • Author(s)
      青木康展,松本みちよ,松本理,増村健一,續輝久,能美健彦
    • Organizer
      日本環境変異原学会第42回大会
    • Place of Presentation
      岡山コンベンションセンター(岡山県岡山市)
    • Data Source
      KAKENHI-PROJECT-25281027
  • [Presentation] DNA repair and translesion DNA synthesis as constituents of “threshold” of genotoxicity2013

    • Author(s)
      T. Nohmi, T. Suzuki, K. Matsumoto and M. Honma
    • Organizer
      The XIII International Congress of Toxicology
    • Place of Presentation
      Seoul, Korea
    • Invited
    • Data Source
      KAKENHI-PROJECT-22241016
  • [Presentation] 2-メチルフランのgpt deltaラットを用いた一般毒性・遺伝毒性・発がん性の包括的評価2013

    • Author(s)
      黑田顕,石井雄二,高須伸二,木島綾希,松下幸平,能美健彦,小川久美子,梅村隆志
    • Organizer
      日本環境変異原学会第42回大会
    • Place of Presentation
      岡山
    • Data Source
      KAKENHI-PROJECT-22241016
  • [Presentation] Introduction and roles of self-defense mechanisms in thresholds for genotoxic chemicals2013

    • Author(s)
      T. Nohmi, T. Suzuki, K. Matsumoto and M. Honma
    • Organizer
      11th International Conference on Environmental Mutagens
    • Place of Presentation
      Iguacu, Brazil
    • Year and Date
      2013-11-06
    • Data Source
      KAKENHI-PROJECT-22241016
  • [Presentation] gpt deltaラット肝臓における自然突然変異および加齢に伴う変異蓄積の検討2013

    • Author(s)
      増村健一,豊田尚美,石井雄二,梅村隆志,能美健彦,西川秋佳,本間正充
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Data Source
      KAKENHI-PROJECT-25281027
  • [Presentation] gpt deltaマウスを用いたENU誘発突然変異と全エクソンシークエンスによる経世代変異の検出2013

    • Author(s)
      増村健一,豊田尚美,権藤洋一,能美健彦,本間正充
    • Organizer
      日本環境変異原学会第42回大会
    • Place of Presentation
      岡山
    • Data Source
      KAKENHI-PROJECT-22241016
  • [Presentation] 環境と発がん:DNAの傷に対する防御と癒し2013

    • Author(s)
      能美健彦
    • Organizer
      環境医学研究所市民公開講座2013
    • Place of Presentation
      名古屋
    • Invited
    • Data Source
      KAKENHI-PROJECT-22241016
  • [Presentation] Spontaneous point mutations and deletions increased with aging in gpt delta transgenic mice and rats2013

    • Author(s)
      K. Masumura, N. Toyoda-Hokaiwado, N. Osugi, Y. Ishii, T. Umemura, H. Takagi, A. Nishikawa, T. Nohmi and M. Honma
    • Organizer
      11th International Conference on Environmental Mutagens
    • Place of Presentation
      Iguacu, Brazil
    • Data Source
      KAKENHI-PROJECT-22241016
  • [Presentation] gpt deltaラットを用いた反復投与毒性・遺伝毒性の包括的試験法の妥当性について2013

    • Author(s)
      赤木純一,チョウ・ヨンマン,豊田武士,大波冴子,水田保子,鈴木勇,能美健彦,西川秋佳,小川久美子
    • Organizer
      第36回日本分子生物学会年会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-22241016
  • [Presentation] Introuctuion: Genotoxicology and Carcinogenesis, Global Progress on Genotoxicity and Carcinogenicity Test Methods2013

    • Author(s)
      T. Nohmi
    • Organizer
      The XIII International Congress of Toxicology
    • Place of Presentation
      Seoul, Korea
    • Invited
    • Data Source
      KAKENHI-PROJECT-22241016
  • [Presentation] Analysis of mutation in the liver of gpt delta rats given a choline-deficient, L-amino acid-defined diet: interplay among nutrition, mutation and cancer2013

    • Author(s)
      T. Nohmi, K. Masumura and D. Nakae
    • Organizer
      4th International Conference on Nutrition and Physical Activities on Aging, Obesity and Cancer
    • Place of Presentation
      Pattaya, Thailand
    • Invited
    • Data Source
      KAKENHI-PROJECT-22241016
  • [Presentation] Mitomycin C によるDNA二本鎖切断誘発に対するDNA polymerase kappaのin vivoにおける役割2013

    • Author(s)
      本山茂樹,竹入章,松尾沙織里,和田直子,寺社下浩一,三島雅之,新見直子,Petr Gruz,増村健一,山田雅巳,能美健彦
    • Organizer
      日本環境変異原学会第42回大会
    • Place of Presentation
      岡山
    • Data Source
      KAKENHI-PROJECT-22241016
  • [Presentation] DNAポリメラーゼゼータはBPDE-N2-dGの損傷乗り越え合成後の伸長時にエラーを誘発する2013

    • Author(s)
      鈴木哲矢,佐々 彰,ピーターグルーズ,足立典隆,本間正充,能美健彦
    • Organizer
      第36回日本分子生物学会年会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-22241016
  • [Presentation] アルケニルベンゼン類によるDNA 付加体形成と遺伝子突然変異の検出2013

    • Author(s)
      石井雄二,高須伸二,松下幸平,黒田顕,能美健彦,小川久美子,梅村隆志
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-22241016
  • [Presentation] 臭素酸カリウムがgpt deltaマウス小腸で誘発する突然変異の閾値と変異スペクトルの用量依存性変化2013

    • Author(s)
      青木康展,松本みちよ,松本理,増村健一,續輝久,能美健彦
    • Organizer
      日本環境変異原学会第42回大会
    • Place of Presentation
      岡山
    • Data Source
      KAKENHI-PROJECT-22241016
  • [Presentation] Spontaneous point mutations and deletions increased with aging in gpt delta transgenic mice and rats2013

    • Author(s)
      Masumura K, Toyoda-Hokaiwado N, Osugi N, Ishii Y, Umemura T, Takagi H, Nishikawa A, Nohmi T, Honma M
    • Organizer
      11th International Conference on Environmental Mutagens
    • Place of Presentation
      Bourbon Cataratas Convention & Spa Resort, Foz do Iguazu, Brazil
    • Data Source
      KAKENHI-PROJECT-25281027
  • [Presentation] MitomycinCによるDNA二本鎖切断誘発に対するDNA polymerase kappaのin vivoにおける役割2013

    • Author(s)
      本山茂記,竹入章,松尾沙織里,和田直子,寺社下浩一,三島雅之,新見直子,Gruz P,増村健一,山田雅巳,能美健彦
    • Organizer
      日本環境変異原学会第42回大会
    • Place of Presentation
      岡山コンベンションセンター(岡山県岡山市)
    • Data Source
      KAKENHI-PROJECT-25281027
  • [Presentation] DNA repar and translesion DNA synthesis as possible mechanisms underlying genotoxic thresholds2012

    • Author(s)
      T. Nohmi
    • Organizer
      United Kingdom Environmental Mutagen Society (UKEMS)
    • Place of Presentation
      Swansea, UK
    • Invited
    • Data Source
      KAKENHI-PROJECT-22241016
  • [Presentation] in vivo mutagenesis: its analysis and underlying mechanisms2012

    • Author(s)
      T. Nohmi
    • Organizer
      6th International Conference on Environmental Mutagens in Human Populations
    • Place of Presentation
      Doha, Qatar
    • Invited
    • Data Source
      KAKENHI-PROJECT-22241016
  • [Presentation] Identification of genomic insertion sites of λEG10 DNA in gpt delta transgenic mice and rats by high-throughput DNA sequencing2012

    • Author(s)
      T. Nohmi
    • Organizer
      51st Annual Meeting of Society of Toxicology
    • Place of Presentation
      San Francisco, U.S.A.
    • Data Source
      KAKENHI-PROJECT-22241016
  • [Presentation] gpt delta マウスを用いた無機ヒ素によるin vivo 突然変異解析2012

    • Author(s)
      内匠正太, 青木康展, 佐野友春, 鈴木武博, 能美健彦, 野原恵子
    • Organizer
      日本環境変異原学会第41回大会
    • Place of Presentation
      静岡
    • Data Source
      KAKENHI-PROJECT-23390166
  • [Presentation] Modulatory effects of capsaicin on N-diethylnitrosamine-induced mutagenesis and hepatocarcinogenesis in gpt delta rats2012

    • Author(s)
      T. Nohmi
    • Organizer
      The 3rd Conference on Environmental Mutgens and 15th Conference on Chinese Environmental Mutagen Society
    • Place of Presentation
      Hangzhou, China
    • Invited
    • Data Source
      KAKENHI-PROJECT-22241016
  • [Presentation] Fukushima accident2012

    • Author(s)
      T. Nohmi
    • Organizer
      Swiss Toxicology Society Annual Meeting 2012
    • Place of Presentation
      Basel, Switerland
    • Invited
    • Data Source
      KAKENHI-PROJECT-22241016
  • [Presentation] Phenylalanine 171 as a molecular brake for translesion DNA synthesis across benzo[a]pyrene adducts by human DNA polymerase kappa2012

    • Author(s)
      T. Nohmi
    • Organizer
      The 4th Japan-US DNA Repair Meeting
    • Place of Presentation
      Maryland, U.S.A.
    • Invited
    • Data Source
      KAKENHI-PROJECT-22241016
  • [Presentation] DNA repair and translesion DNA synthesis as possible mechanisms underlying genotoxic thresholds2012

    • Author(s)
      T, Nohmi
    • Organizer
      UKEMS
    • Place of Presentation
      Swansea, UK
    • Data Source
      KAKENHI-PROJECT-22241016
  • [Presentation] 遺伝子と環境:遺伝毒性の基礎2012

    • Author(s)
      能美健彦
    • Organizer
      第6回応用トキシコロジー リカレント講座
    • Place of Presentation
      大阪
    • Invited
    • Data Source
      KAKENHI-PROJECT-22241016
  • [Presentation] Genotoxic thresholds: identification of mutations in vivo and mechanistic studies in vitro,2011

    • Author(s)
      T. Nohmi
    • Organizer
      2nd International Symposium on Genotoxic and Carcinogenic Thresholds
    • Place of Presentation
      Tokyo, Japan
    • Invited
    • Data Source
      KAKENHI-PROJECT-22241016
  • [Presentation] 大気汚染物質によるgpt deltaマウス肺中の突然変異とヒト肺がん組織中p53遺伝子の突然変異の比較2011

    • Author(s)
      青木康展,松本理,能美健彦
    • Organizer
      日本環境変異原学会第40回大会
    • Place of Presentation
      一橋記念講堂(東京都)
    • Year and Date
      2011-11-21
    • Data Source
      KAKENHI-PROJECT-21390038
  • [Presentation] Critical roles of mismatch repair proteins in modulation of genotoxicity of gamma-irradiation in human cells by pretreatments with N-methyl-N’-nitro-N-nitrosoguanidine at low doses2011

    • Author(s)
      T. Nohmi
    • Organizer
      14th International Congress of Radiation Research
    • Place of Presentation
      Warszawa, Poland
    • Data Source
      KAKENHI-PROJECT-22241016
  • [Presentation] Genotoxic thresholds : identification of mutations in vivo and mechanistic studies in vitro2011

    • Author(s)
      T. Nohmi, K. Masumura, P Gruz, N. Toyoda-Hokaiwado, M. Takamune, N. Niimi, T. Suzuki, Y. Kanemaru, M. Yasui, M. Yamada, M. Honma, N. Adachi and A. Nishikawa
    • Organizer
      2nd International Symposium on Genotoxic and Carcinogenic Thresholds
    • Place of Presentation
      Tokyo
    • Year and Date
      2011-11-23
    • Data Source
      KAKENHI-PROJECT-22241016
  • [Presentation] 大気中の粒子状物質抽出物がgpt deltaマウス肺中に示す変異原性; 2009年つくば市内, 1989年バンコク市内の試料について2010

    • Author(s)
      青木康展,佐藤陽美,中島大介,影山志保,阪下由香利,柳澤利枝,後藤純雄,松下秀鶴,増村健一,能美健彦
    • Organizer
      日本環境変異原学会第39回大会
    • Place of Presentation
      つくば国際会議場(茨城県)
    • Year and Date
      2010-11-17
    • Data Source
      KAKENHI-PROJECT-21390038
  • [Presentation] Chemopreventive effects of silymarin, a plant constituent, against the carcinogenicity of dimethylhydrazine plus dextran sodium sulfate in the colon of gpt delta transgenic rats2010

    • Author(s)
      T.Nohmi
    • Organizer
      The 10^<th> International Conference on Mechanisms of Antimutagenesis and Anticarcinogenesis (ICMAA)
    • Place of Presentation
      ブラジル、グラルージャ
    • Year and Date
      2010-09-27
    • Data Source
      KAKENHI-PROJECT-22241016
  • [Presentation] Transgenic in vivo genotoxicity assays : current status of gpt delta transgenic mice and rats2010

    • Author(s)
      T. Nohmi
    • Organizer
      The 2nd Asian Conference on Environmental Mutagens
    • Place of Presentation
      Pattaya, Thailand
    • Data Source
      KAKENHI-PROJECT-22241016
  • [Presentation] ディーゼルナノ粒子長期曝露によりgpt deltaマウス肺・肝臓に誘導される突然変異2010

    • Author(s)
      佐藤陽美, 阪下由香利, 増村健一, 古山昭子, 平野靖史郎, 能美健彦, 青木康展
    • Organizer
      日本環境変異原学会 第38回大会
    • Place of Presentation
      つくば国際会議場(茨城県)
    • Year and Date
      2010-11-16
    • Data Source
      KAKENHI-PROJECT-21390038
  • [Presentation] 遺伝子改変動物を用いる遺伝毒性試験の開発と評価2010

    • Author(s)
      能美健彦
    • Organizer
      第26回日本毒性病理学会学術集会
    • Place of Presentation
      金沢
    • Year and Date
      2010-02-03
    • Data Source
      KAKENHI-PROJECT-18201010
  • [Presentation] Nucleotide pool damage and Y-family DNA polymerases2010

    • Author(s)
      T. Nohmi
    • Organizer
      Gorden Research Conferences, DNA damage, mutation & cancer, Ventura
    • Place of Presentation
      CA, USA
    • Data Source
      KAKENHI-PROJECT-18201010
  • [Presentation] Nucleotide pool damage and Y-family DNA polymerases2010

    • Author(s)
      T.Nohmi
    • Organizer
      Gordon Research Conferences, DNA damage, mutation & cancer
    • Place of Presentation
      米国、カリフォルニア州、ベンチュラ
    • Year and Date
      2010-03-21
    • Data Source
      KAKENHI-PROJECT-18201010
  • [Presentation] 遺伝毒性の基礎2010

    • Author(s)
      能美健彦
    • Organizer
      第11回日本トキシコロジー学会生涯教育講習会
    • Place of Presentation
      沖縄
    • Year and Date
      2010-06-15
    • Data Source
      KAKENHI-PROJECT-22241016
  • [Presentation] ディーゼルナノ粒子長期曝露によりgpt deltaマウス肺・肝臓に誘導される突然変異2010

    • Author(s)
      佐藤陽美,阪下由香利,増村健一,古山昭子,平野靖史郎,能美健彦,青木康展
    • Organizer
      日本環境変異原学会第39回大会
    • Place of Presentation
      つくば国際会議場(茨城県)
    • Year and Date
      2010-11-17
    • Data Source
      KAKENHI-PROJECT-21390038
  • [Presentation] In vivo mutagenicity of ambient air in the lungs of gpt delta transgenicmice ; A case study in Tsukuba city, Japan.2010

    • Author(s)
      Sato H., Nakajima D., Kageyama S., Sakashita Y., Yanagisawa R., Masumura K., Nohmi T., Aoki Y.
    • Organizer
      2nd Asian Conf.Environ.Mutagens
    • Place of Presentation
      Dusit Thani Hotel (Pattaya, Thailand)
    • Year and Date
      2010-12-16
    • Data Source
      KAKENHI-PROJECT-21390038
  • [Presentation] In vivo mutagenicity of ambient air in the lungs of gpt delta transgenic mice ; A case study in Tsukuba city, Japan2010

    • Author(s)
      Sato H, Nakajima D, Kageyama S, Sakashita Y, Yanagisawa R, Masumura K, Nohmi T, Aoki Y
    • Organizer
      2^<nd> Asian Conf. Environ. Mutagens
    • Place of Presentation
      Dusit Thani Hotel(Pattaya, Thailand)
    • Year and Date
      2010-12-16
    • Data Source
      KAKENHI-PROJECT-21390038
  • [Presentation] Phenylalanine 171 as a molecular brake for dCMP incorporation opposite benzo[a]pyrene-guanine adducts by human DNA polymerase kappa2010

    • Author(s)
      T.Nohmi
    • Organizer
      The 7^<th> 3R symposium, Toyama
    • Place of Presentation
      富山
    • Year and Date
      2010-10-29
    • Data Source
      KAKENHI-PROJECT-22241016
  • [Presentation] Transgenic in vivo genotoxicity assays : current status of gpt delta transgenic mice and rats2010

    • Author(s)
      T.Nohmi
    • Organizer
      The 2^<nd> Asian Conference on Environmental Mutagens
    • Place of Presentation
      タイ、パタヤ
    • Year and Date
      2010-12-17
    • Data Source
      KAKENHI-PROJECT-22241016
  • [Presentation] Y-family DNA polymerases and nucleotide pool damage2010

    • Author(s)
      T.Nohmi
    • Organizer
      第33回日本分子生物学会年会、第83回日本生化学会大会合同年会
    • Place of Presentation
      神戸
    • Year and Date
      2010-12-07
    • Data Source
      KAKENHI-PROJECT-22241016
  • [Presentation] gpt delta transgenic mouse and rat for in vivo genotoxicity assays2010

    • Author(s)
      T.Nohmi
    • Organizer
      The 2^<nd> Westlake Conference-Translational Medicine
    • Place of Presentation
      中国、杭州
    • Year and Date
      2010-06-26
    • Data Source
      KAKENHI-PROJECT-22241016
  • [Presentation] ヒト細胞におけるDNAポリメラーゼκの機能解析2009

    • Author(s)
      新見直子, 飯泉晋, 足立典隆, 小山秀樹, 能美健彦
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-18201010
  • [Presentation] Erroneous incorporation of oxidized nucleotides by Y-family DNA polymerases2009

    • Author(s)
      A. Katafuchi, A. Sassa, N. Niimi, P. Gruz, H. Fujimoto, C. Masutani, F. Hanaoka, T. Ohta, T. Nohmi
    • Organizer
      10th International Conference on Environmental Mutagens in Firenze
    • Place of Presentation
      Italy
    • Data Source
      KAKENHI-PROJECT-18201010
  • [Presentation] A crucial role for the steric gate amino acid tyrosine 112 in efficient mismatched-primer2009

    • Author(s)
      T. Nohmi
    • Organizer
      extension by human DNA polymerase k, ASM Conferences, DNA Repair and Mutagenesis
    • Place of Presentation
      Whistler, Canada
    • Year and Date
      2009-06-01
    • Data Source
      KAKENHI-PROJECT-18201010
  • [Presentation] In vivo mutagenesis induced by the air pollutants in the test is of gpt delta transgenic mice2009

    • Author(s)
      Aoki Y, Hashimoto AH, Amanuma K, Matsumoto M, Masumura K, Nohmi T
    • Organizer
      21st Cent.Adv.Mol.Toxicol.Environ.Chem.Pathog.Dis.
    • Place of Presentation
      Tokyo
    • Year and Date
      2009-10-26
    • Data Source
      KAKENHI-PROJECT-21390038
  • [Presentation] In vivo mutagenesis induced by the air pollutants in the testis of gpt delta transgenic mice2009

    • Author(s)
      Aoki Y, Hashimoto AH, Amanuma K, Matsumoto M, Masumura K, Nohmi T
    • Organizer
      21st Cent. Adv. Mol. Toxicol. Environ. Chem. Pathog. Dis
    • Place of Presentation
      東京大学医学部鉄門講堂(東京都)
    • Year and Date
      2009-10-26
    • Data Source
      KAKENHI-PROJECT-21390038
  • [Presentation] Establishment of of human cell lines lacking the catalytic activity of DNA polymerase kappa involved in translesion DNA synthesis2009

    • Author(s)
      N. Niimi, P. Gruz, S. Iiizumi, N. Adachi, H. Koyama, T. Nohmi
    • Organizer
      The 40th International Symposium of the Princess Takamatsu Cancer Research Foundation
    • Place of Presentation
      Tokyo
    • Data Source
      KAKENHI-PROJECT-18201010
  • [Presentation] Possible mechanisms underlying practical thresholds for genotoxic carcinogens2009

    • Author(s)
      T. Nohmi
    • Organizer
      10th International Conference on Environmental Mutagens in Firenze
    • Place of Presentation
      Italy
    • Data Source
      KAKENHI-PROJECT-18201010
  • [Presentation] Genotoxic versus non-genotoxic mechanisms : feed-back from Genotoxic and Carcinogenic Thresholds in Tokyo2009

    • Author(s)
      T.Nohmi
    • Organizer
      5^<th> International Workshop on genotoxicity testing
    • Place of Presentation
      バーゼル、スイス
    • Year and Date
      2009-08-19
    • Data Source
      KAKENHI-PROJECT-18201010
  • [Presentation] A crucial role for the steric gate amino acid tyrosine 112 in efficient mismatched-primer extension by human DNA polymeraseκ2009

    • Author(s)
      N. Niimi, A. Sassa, A. Katafuchi, P. Gruz, H. Fujimoto, R. -R. Bonala, F. Johnson, T. Ohta, T. Nohmi
    • Organizer
      ASM Conferences, DNA Repair and Mutagenesis in Whistler
    • Place of Presentation
      BC, Canada
    • Data Source
      KAKENHI-PROJECT-18201010
  • [Presentation] gpt delta transgenic rats and mice for genotoxicity assays : identification of genetic alterations at target organs of chemical carinogens2009

    • Author(s)
      T.Nohmi
    • Organizer
      United Kingdom Environmental Mutagen Society 32^<nd> Annual Meeting
    • Place of Presentation
      リーズ、英国
    • Year and Date
      2009-07-13
    • Data Source
      KAKENHI-PROJECT-18201010
  • [Presentation] Current status of F344 gpt delta rats for in vivo mutagenesis2009

    • Author(s)
      T.Nohmi
    • Organizer
      5^<th> International Workshop on genotoxicity testing
    • Place of Presentation
      バーゼル、スイス
    • Year and Date
      2009-08-19
    • Data Source
      KAKENHI-PROJECT-18201010
  • [Presentation] Development of gpt delta transgenic mice and rats for genotoxicity assays2009

    • Author(s)
      T.Nohmi
    • Organizer
      The 5^<th> International Congress of Asian Society of Toxicology
    • Place of Presentation
      台北、台湾
    • Year and Date
      2009-09-13
    • Data Source
      KAKENHI-PROJECT-18201010
  • [Presentation] Possible mechanisms underlying practical thresholds for genotoxic carcinogens2009

    • Author(s)
      T.Nohmi
    • Organizer
      10^<th> International Conference on Environmental Mutagens
    • Place of Presentation
      フィレンツェ、イタリア
    • Year and Date
      2009-08-22
    • Data Source
      KAKENHI-PROJECT-18201010
  • [Presentation] Control of multiple DNA polymerases dealing with lesions induced by environmental mutagens2009

    • Author(s)
      T. Nohmi, K. Kokubo, M. Yamada, P. Gruz
    • Organizer
      36th Annual Meeting of the European Environmental Mutagen Society in Prague
    • Place of Presentation
      Czech
    • Data Source
      KAKENHI-PROJECT-18201010
  • [Presentation] Genotoxic versus non-genotoxic mechanisms: feed-back from Genotoxic and Carcinogenic Thresholds in Tokyo2009

    • Author(s)
      T. Nohmi
    • Organizer
      5th International Workshop on genotoxicity testing, Basel
    • Place of Presentation
      Switzerland
    • Data Source
      KAKENHI-PROJECT-18201010
  • [Presentation] Transgenic in vivo genotoxicity assays : basic features and the possible applications2008

    • Author(s)
      T. Nohmi
    • Organizer
      14^<th> Alexander Hollaender Course on Genetic Toxicology : Genomic and Proteomic Approaches & Special Workshop on Arsenic Exposure Assessment in Kolkata
    • Place of Presentation
      Kolkata, India
    • Year and Date
      2008-12-11
    • Data Source
      KAKENHI-PROJECT-18201010
  • [Presentation] Combined genotoxic effects of a methylating agent and radiation on human cells2008

    • Author(s)
      T. Nohmi
    • Organizer
      New Nuclear Research Symposium, Biological Responses to Low Dose Radiation
    • Place of Presentation
      北九州、福岡
    • Year and Date
      2008-11-18
    • Data Source
      KAKENHI-PROJECT-18201010
  • [Presentation] Possible Mechanisms of Practical Genotoxic Thresholds2008

    • Author(s)
      T. Nohmi
    • Organizer
      International Symposium on Genotoxic and Carcinogenic Thresholds
    • Place of Presentation
      東京
    • Year and Date
      2008-07-22
    • Data Source
      KAKENHI-PROJECT-18201010
  • [Presentation] Recent Topics of Mutation Research with gpt delta Mice and Rats2008

    • Author(s)
      T. Nohmi
    • Organizer
      39^<th> Annual Meeting of Environmental Mutagen Society
    • Place of Presentation
      Puerto Rico
    • Year and Date
      2008-10-22
    • Data Source
      KAKENHI-PROJECT-18201010
  • [Presentation] Validity of gpt delta transgenic rodent genotoxicity assays2008

    • Author(s)
      T.Nohmi
    • Organizer
      47^<th>Annual Meeting of Society of Toxicology
    • Place of Presentation
      Seattle,U.S.A.
    • Year and Date
      2008-03-19
    • Data Source
      KAKENHI-PROJECT-18201010
  • [Presentation] gpt delta transgenic mice for in vivo genotoxicity assays : application for analysis of combined effects of radiation and chemicals2008

    • Author(s)
      T. Nohmi
    • Organizer
      The 7th Japan-France Workshop on Radiation Biology
    • Place of Presentation
      稲毛、千葉
    • Year and Date
      2008-10-15
    • Data Source
      KAKENHI-PROJECT-18201010
  • [Presentation] Possible Mechanisms of Practical Genotoxic Thresholds2008

    • Author(s)
      T. Nohmi
    • Organizer
      International Symposium on Genotoxic and Carcinogenic Thresholds
    • Place of Presentation
      Tokyo
    • Data Source
      KAKENHI-PROJECT-18201010
  • [Presentation] Development of in vivo genotoxicity assays with transgenic mice and rats,Intrnational Symposium on the Predictive2008

    • Author(s)
      T.Nohmi
    • Organizer
      Preventive and Mechanistic Mutagenesis & XXXIII EMSI Annual Meeting
    • Place of Presentation
      Aligarh,India
    • Year and Date
      2008-01-02
    • Data Source
      KAKENHI-PROJECT-18201010
  • [Presentation] in vivo 突然変異を解析するための gpt delta トランスジェニックマウスおよびラット2008

    • Author(s)
      能美健彦
    • Organizer
      日本環境変異原学会第37回大会
    • Place of Presentation
      宜野湾、沖縄
    • Year and Date
      2008-12-04
    • Data Source
      KAKENHI-PROJECT-18201010
  • [Presentation] Oxidative DNA damage and its genotoxic consequence in vivo2008

    • Author(s)
      T.Nohmi
    • Organizer
      Joint-meeting of the Genes, Environment and Diseases Panels, the US-Japan Cooperative Medical Science Program
    • Place of Presentation
      San Francisco, U.S.A.
    • Year and Date
      2008-03-27
    • Data Source
      KAKENHI-PROJECT-18201010
  • [Presentation] ヌクレオチドプールの酸化を介したDNA損傷と突然変異2008

    • Author(s)
      能美 健彦
    • Organizer
      情報計算化学生物学会
    • Place of Presentation
      東京
    • Year and Date
      2008-02-04
    • Data Source
      KAKENHI-PROJECT-18201010
  • [Presentation] Roles of Y-family DNA polymerases in mutagenesis via the misincorporation of oxidized dNTPs2007

    • Author(s)
      T. Nohmi
    • Organizer
      The 3rd Japan US DNA repair meeting in Sendai
    • Place of Presentation
      Japan
    • Data Source
      KAKENHI-PROJECT-18201010
  • [Presentation] Suppression of radiation-induced large deletions by combined treatments with a tobacco-specific nitrosamine in the lung of gpt delta transgenic mice,New Nuclear Research Symposium2007

    • Author(s)
      M.Ikeda, K.Masumura, Y.Sakamoto, B.Wang, M.Nenoi, K.Sakuma, I.Hayata, and T.Nohmi
    • Organizer
      New Nuclear Research Symposium, Biological Responses to Low Dose Radiation
    • Place of Presentation
      千葉
    • Year and Date
      2007-11-14
    • Data Source
      KAKENHI-PROJECT-18201010
  • [Presentation] Chemopreventive effects of nobiletin,a citrus constituent,against the genotoxicity of NNK,a tobacco-specific nitrosamine,in the lung of gpt delta transgenic mice2007

    • Author(s)
      M.Ikeda, K.Masumura, K.Matsui, H.Kohno, K.Sakuma, T.Tanaka, T.Kamataki, and T.Nohmi
    • Organizer
      The 9^<th>International Conference on Mechanisms of Antimutagenesis and Anticarcinogenesis(ICMAA-2007)
    • Place of Presentation
      Cheju,Korea
    • Year and Date
      2007-12-04
    • Data Source
      KAKENHI-PROJECT-18201010
  • [Presentation] 大腸菌DNAポリメラーゼIIIによる酸化的損傷ヌクレオチドの取り込み2007

    • Author(s)
      清水 雅富, P.Gruz, 藤井 慎吾, 紙谷 浩之, 徐岩, 碓井 之雄, 杉山 弘, 原島 秀吉, R. P.Fuchs, 能美 健彦
    • Organizer
      第30回日本分子生物学会, 第80回日本生化学会合同大会
    • Place of Presentation
      東京
    • Year and Date
      2007-12-13
    • Data Source
      KAKENHI-PROJECT-18201010
  • [Presentation] DNA repair as a constituent of thresholds of genotoxicity2007

    • Author(s)
      T.Nohmi
    • Organizer
      37^<th>European Environmental Mutagen Society
    • Place of Presentation
      Basel,Switzerland
    • Year and Date
      2007-09-11
    • Data Source
      KAKENHI-PROJECT-18201010
  • [Presentation] Chemopreventive effects of nobiletin against genotoxicity induced by NNK in the lung of gpt delta transgenic mice2007

    • Author(s)
      K.Masumura, M.Ikeda, K.Matsui, T.Tanaka, and T.Nohmi
    • Organizer
      1^<st>Asian Conference on Environmental Mutagens(1^<st>ACEM)/36^<th>Annual Meeting of the Japanese Environmental Mutagen Society(36^<th>JEMS)
    • Place of Presentation
      北九州
    • Year and Date
      2007-11-29
    • Data Source
      KAKENHI-PROJECT-18201010
  • [Presentation] Antigenotoxic effects of p53 on UVB-induced and spontaneous dele tions in the murine epidermis2007

    • Author(s)
      Y.Sakamoto, M.Ikeda, K.Masumura, Y.Asami, T.Tsukamoto, H.Ikehata, Y.Kuroiwa, T.Umemura, A.Nishikawa, M.Tatematsu, T.Ono and T.Nohmi
    • Organizer
      1^<st>Asian Conference on Environmental Mutagens(1^<st>ACEM)/36^<th>Annual Meeting of the Japanese Environmental Mutagen Society(36^<th>JEMS)
    • Place of Presentation
      北九州
    • Year and Date
      2007-11-29
    • Data Source
      KAKENHI-PROJECT-18201010
  • [Presentation] Translesion synthesis past 2'-deoxyinosine,a major nitric oxide-induced DNA adduct,by human DNA polymerase eta and kappa2007

    • Author(s)
      M.Yasui, E.Suenaga, N.Koyama, C.Masutani, F.Hanaoka, P.Gruz, S.Shibutani, T.Nohmi, M.Hayashi, and M.Honma
    • Organizer
      1^<st>Asian Conference on Environmental Mutagens(1^<st>ACEM)/36^<th>Annual Meeting of the Japanese Environmental Mutagen Society(36^<th>JEMS)
    • Place of Presentation
      北九州
    • Year and Date
      2007-11-29
    • Data Source
      KAKENHI-PROJECT-18201010
  • [Presentation] アスコルビン酸と亜硝酸ナトリウム複合影響による変異原性ならびにラット前胃発がんイニシェーション作用の検索2007

    • Author(s)
      黒岩 有一、山田 雅巳、松井 恵子、増村 健一、岡村 俊也、田崎 雅子、梅村 隆志、能美 健彦、西川 秋佳、広瀬 雅雄
    • Organizer
      第34回日本トキシコロジー学会学術年会
    • Place of Presentation
      東京
    • Year and Date
      2007-06-27
    • Data Source
      KAKENHI-PROJECT-18201010
  • [Presentation] ヒトDNAポリメラーゼκの損傷DNAに対する親和性と伸長反応の解析2007

    • Author(s)
      新見 直子, 佐々 彰, 片渕 淳, ピーター グルーズ, 能美 健彦
    • Organizer
      第30回日本分子生物学会, 第80回日本生化学会合同大会
    • Place of Presentation
      東京
    • Year and Date
      2007-12-13
    • Data Source
      KAKENHI-PROJECT-18201010
  • [Presentation] DNA repair as a constituent of thresholds of genotoxicity2007

    • Author(s)
      T. Nohmi
    • Organizer
      37th European Environmental Mutagen Society
    • Place of Presentation
      Basel, Switzerland
    • Data Source
      KAKENHI-PROJECT-18201010
  • [Presentation] Asbestos and other environmental toxic chemicals2007

    • Author(s)
      T.Nohmi
    • Organizer
      The 5^<th>International Conference on Environmental Mutagens in Human Populations in Antalya
    • Place of Presentation
      Antalya,Turkey
    • Year and Date
      2007-05-23
    • Data Source
      KAKENHI-PROJECT-18201010
  • [Presentation] Dose dependency of combined effects of ionizing radiation and other agents on cancer induction2007

    • Author(s)
      Y.Shimada, M.Nishimura, S.Kakinuma, K.Yamauchi, T.Imaoka, Y.Shang, T.Nohmi, I.Kawaguchi, M.Doi
    • Organizer
      New Nuclear Research Symposium, Biological Responses to Low Dose Radiation
    • Place of Presentation
      東京
    • Year and Date
      2007-11-13
    • Data Source
      KAKENHI-PROJECT-18201010
  • [Presentation] The role of Y-family DNA polymerase in oxidative mutagenesis2007

    • Author(s)
      T.Nohmi
    • Organizer
      38^<th>Annual Meeting of Environmental Mutagen Society
    • Place of Presentation
      Atlanta,U.S.A.
    • Year and Date
      2007-10-22
    • Data Source
      KAKENHI-PROJECT-18201010
  • [Presentation] in vivo mutations by 3,6-dinitrobenzo[e]pyrene instilled into the lung of gpt delta transgenic mice2007

    • Author(s)
      M.Matsumoto, K.Amanuma, A. H.Hashimoto, Y.Sakashita, R.Yanagisawa, H.Takano, K.Masumura, T.Nohmi, K.Wakabyashi, T.Watanabe, and Y.Aoki
    • Organizer
      1^<st>Asian Conference on Environmental Mutagens(1^<st>ACEM)/36^<th>Annual Meeting of the Japanese Environmental Mutagen Society(36^<th>JEMS)
    • Place of Presentation
      北九州
    • Year and Date
      2007-11-29
    • Data Source
      KAKENHI-PROJECT-18201010
  • [Presentation] gpt-deltaマウスを用いた複合曝露胸腺細胞における欠失変異の解析2007

    • Author(s)
      山内 一己, 柿沼 志津子, 須藤 聡美, 太田 有紀, 鬼頭 誠司, 増村 健一, 能美 健彦, 西村 まゆみ, 島田 義也
    • Organizer
      日本放射線影響学会第50回大会
    • Place of Presentation
      千葉
    • Year and Date
      2007-11-14
    • Data Source
      KAKENHI-PROJECT-18201010
  • [Presentation] Formation of RNA adduct with a novel endogenous mutagen and carcinogen,aminophenylnorharman2007

    • Author(s)
      Y.Totsuka, R.Nishigaki, T.Takamura-Enya, T.Nohmi, T.Sugimura, and K.Wakabayashi
    • Organizer
      38^<th>Annual Meeting of Environmental Mutagen Society
    • Place of Presentation
      Atlanta,U.S.A.
    • Year and Date
      2007-10-22
    • Data Source
      KAKENHI-PROJECT-18201010
  • [Presentation] The role of Y-family DNA polymerase in oxidative mutagenesis2007

    • Author(s)
      T. Nohmi
    • Organizer
      38th Annual Meeting of Environmental Mutagen Society in Atlanta
    • Place of Presentation
      USA
    • Data Source
      KAKENHI-PROJECT-18201010
  • [Presentation] Novel Salmonella strains highly sensitive to mutagens that cause oxidized pyrimidines in DNA2007

    • Author(s)
      M.Yamada, K.Matui,and T.Nohmi
    • Organizer
      1^<st>Asian Conference on Environmental Mutagens(1^<st>ACEM)/36^<th>Annual Meeting of the Japanese Environmental Mutagen Society(36^<th>JEMS)
    • Place of Presentation
      北九州
    • Year and Date
      2007-11-29
    • Data Source
      KAKENHI-PROJECT-18201010
  • [Presentation] Existence of thresholds for carcinogenicity and in vivo mutagenicity of 1,4-dioxane in liver of rats2007

    • Author(s)
      大西 真理子, 大森 雅子, 魏民, 増村 健一, 能美 健彦, 鰐淵 英機, 福島 昭治
    • Organizer
      第66回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2007-10-03
    • Data Source
      KAKENHI-PROJECT-18201010
  • [Presentation] Development of bacteria genotoxicity assays:past,present and future perspective2007

    • Author(s)
      T.Nohmi
    • Organizer
      VIII Congresso Brasileiro de Mutagenese Carcinogenese e Teratogenese Ambiental(SBMCTA2007)
    • Place of Presentation
      Angra dos Reis,Brazil
    • Year and Date
      2007-10-31
    • Data Source
      KAKENHI-PROJECT-18201010
  • [Presentation] Effects of human Y-family DNA polymerases expressed in the enterobacterial mutagenicity tester strains2007

    • Author(s)
      P.Gruz, K.Matsui, and T.Nohmi
    • Organizer
      1^<st>Asian Conference on Environmental Mutagens(1^<st>ACEM)/36^<th> Annual Meeting of the Japanese Environmental Mutagen Society(36^<th>JEMS)
    • Place of Presentation
      北九州
    • Year and Date
      2007-11-29
    • Data Source
      KAKENHI-PROJECT-18201010
  • [Presentation] Generation and characterization of human cells knocked-in and knocked-out of DNA polymerase kappa2007

    • Author(s)
      N.Niimi,and T.Nohmi
    • Organizer
      1^<st>Asian Conference on Environmental Mutagens(1^<st>ACEM)/36^<th>Annual Meeting of the Japanese Environmental Mutagen Society (36^<th>JEMS)
    • Place of Presentation
      北九州
    • Year and Date
      2007-11-29
    • Data Source
      KAKENHI-PROJECT-18201010
  • [Presentation] Roles of Y-family DNA polymerases in mutagenesis via the misincorporation of oxidized dNTPs2007

    • Author(s)
      T.Nohmi
    • Organizer
      The 3^<rd>Japan US DNA repair meeting
    • Place of Presentation
      仙台
    • Year and Date
      2007-05-09
    • Data Source
      KAKENHI-PROJECT-18201010
  • [Presentation] Validity of in vivo genotoxicology2007

    • Author(s)
      T.Nohmi
    • Organizer
      6^<th>World Congress on Alternatives & Animal Use in the Life Sciences
    • Place of Presentation
      東京
    • Year and Date
      2007-08-23
    • Data Source
      KAKENHI-PROJECT-18201010
  • [Presentation] Roles of translesion DNA synthesis in threshold for genotoxic chemicals

    • Author(s)
      T. Nohmi, T. Suzuki, K. Matsumoto and M. Honma,
    • Organizer
      The 4th Asian Conference on Environmental Mutagens
    • Place of Presentation
      Kolkata, India
    • Year and Date
      2014-12-10 – 2014-12-12
    • Invited
    • Data Source
      KAKENHI-PROJECT-26281029
  • [Presentation] Mitomycin CによるDNA損傷に対するDNA polymerase kappaの役割; γH2AXを指標にした免疫組織学的解析 -

    • Author(s)
      本山繁記、竹入章、松尾沙織里、和田直子、寺社下浩一、三島雅之、新見直子、Petr Gruz、増村健一、山田雅巳、能美健彦
    • Organizer
      日本環境変異原学会第43回大会
    • Place of Presentation
      東京
    • Year and Date
      2014-12-04 – 2014-12-05
    • Data Source
      KAKENHI-PROJECT-26281029
  • [Presentation] gpt deltaラットの加齢により誘発される点突然変異および欠失変異の解析

    • Author(s)
      増村健一,豊田尚美,石井雄二,梅村隆志,能美健彦,西川秋佳,本間正充
    • Organizer
      第37回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PROJECT-25281027
  • [Presentation] Mitomycin CによるDNA損傷に対するDNA polymerase kappaの役割 -γH2AXを指標にした免疫組織学的解析

    • Author(s)
      本山茂記,竹入章,松尾沙織里,和田直子,寺社下浩一,三島雅之,新見直子,Petr Grúz,増村健一,山田雅巳,能美健彦
    • Organizer
      日本環境変異原学会第43回大会
    • Place of Presentation
      一橋講堂
    • Year and Date
      2014-12-04 – 2014-12-05
    • Data Source
      KAKENHI-PROJECT-25281027
  • [Presentation] マウス全エクソンシークエンス解析による経世代突然変異の測定

    • Author(s)
      増村健一,豊田尚美,権藤洋一,能美健彦,本間正充
    • Organizer
      日本環境変異原学会第43回大会
    • Place of Presentation
      一橋講堂
    • Year and Date
      2014-12-04 – 2014-12-05
    • Data Source
      KAKENHI-PROJECT-25281027
  • [Presentation] gpt deltaマウスを用いた加齢に伴い蓄積する遺伝子突然変異の解析

    • Author(s)
      増村健一,大杉直弘,豊田尚美,能美健彦,本間正充
    • Organizer
      日本進化学会第16回大会
    • Place of Presentation
      高槻現代劇場
    • Year and Date
      2014-08-21 – 2014-08-24
    • Data Source
      KAKENHI-PROJECT-25281027
  • [Presentation] DNA polymerase kappaのヒトゲノム恒常性維持における構造的および触媒的役割の検討

    • Author(s)
      兼丸祐紀、鈴木哲矢、新見直子、Petr Gruz、松元郷六、足立典隆、本閒正充、能美健彦
    • Organizer
      第37回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2014-11-25 – 2014-11-27
    • Data Source
      KAKENHI-PROJECT-26281029
  • [Presentation] Structural and catalytic roles of DNA polymerase κ in genome integrity of human cells

    • Author(s)
      Y. Kanemaru, T. Suzuki, N. Niimi, P. Gruz, K. Matsumoto, N. Adachi, M. Honma and T. Nohmi
    • Organizer
      Gordon Research Conference (Genetic Instability)
    • Place of Presentation
      Hong Kong, China
    • Year and Date
      2014-07-06 – 2014-07-11
    • Data Source
      KAKENHI-PROJECT-26281029
  • [Presentation] Point mutations and deletions induced by aging in liver of gpt delta transgenic rats

    • Author(s)
      Masumura K, Toyoda-Hokaiwado N, Ishii Y, Umemura T, Honma M, Nishikawa A, Nohmi T
    • Organizer
      4th Asian Conference on Environmental Mutagens
    • Place of Presentation
      CSIR-Indian Institute of Chemical Biology, Kolkata, India
    • Year and Date
      2014-12-10 – 2014-12-12
    • Data Source
      KAKENHI-PROJECT-25281027
  • [Presentation] ベンゾ[a]ピレンを気管内投与したgpt deltaマウス肺中に誘導された突然変異の加齢に伴う変化

    • Author(s)
      青木康展,橋本顕子,菅原良樹,荒井孝子,後藤佐多良、増村健一,能美健彦
    • Organizer
      日本環境変異原学会第43回大会
    • Place of Presentation
      一橋講堂
    • Year and Date
      2014-12-04 – 2014-12-05
    • Data Source
      KAKENHI-PROJECT-25281027
  • 1.  AOKI Yasunobu (20159297)
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    # of Collaborated Products: 11 results
  • 2.  MASUMURA Kenichi (40291116)
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    # of Collaborated Products: 46 results
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  • 18.  SATOH Hiroshi (40125571)
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    # of Collaborated Projects: 1 results
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  • 36.  MATSUMOTO Yutaka
    # of Collaborated Projects: 1 results
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  • 37.  TANAKA Noriho
    # of Collaborated Projects: 1 results
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  • 38.  Suzuki Tetsuya
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  • 39.  権藤 洋一
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