Sunazuka Toshiaki 砂塚敏明

… Alternative Names

SUNAZUKA Toshiaki 砂塚敏明

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Researcher Number	30226592
Other IDs
External Links
Affiliation (Current)	2025: 北里大学, 感染制御科学府, 教授
Affiliation (based on the past Project Information) *help	2014 – 2023: 北里大学, 感染制御科学府, 教授 2021: 北里大学, 感染制御科学府, 教授、所長 2012 – 2013: 北里大学, その他の研究科, 教授 2011: 北里大学, 人間・環境学研究科(研究院), 教授 2009 – 2011: Kitasato University, 大学院・感染制御科学府, 教授 … More 2010: 北里大学, 感染制御科学府, 教授 2004 – 2008: 北里大学, 北里生命科学研究所, 教授 2002 – 2003: Kitasato University, Kitasato University, Kitasato Institute for life Science, Associate Professor 2000 – 2001: 北里大学, 薬学部, 講師 1995 – 1998: 北里大学, 薬学部, 講師 Less
Review Section/Research Field	Principal Investigator Chemical pharmacy / Science and Engineering / Chemical pharmacy / Basic Section 33020:Synthetic organic chemistry-related / Science and Engineering Except Principal Investigator Basic Section 57030:Conservative dentistry-related / Medium-sized Section 53:Organ-based internal medicine and related fields / General internal medicine (including Psychosomatic medicine) / Chemical pharmacy / Otorhinolaryngology / Chemical pharmacy
Keywords	Principal Investigator 全合成 / 不斉合成 / 生理活性天然物 / 生理活性 / インドール / 天然物 / ピリピロペン / α-ピロン / 絶対構造決定 / マクロライド … More / 特異構造 / 生物活性 / 合成化学 / 分子骨格構築 / アリスガシン / 立体選択的 / メロ-テルペノイド / ACAT / 抗感染症薬 / 抗生物質 / 生物活性天然物 / IL-6 / カスケード反応 / マジンドリン / 含窒素 / 癌 / 生体分子 / メローテルペノイド / カップリング / AChE / Click Chemistry / ビアリールエーテル / In situ Click Chemistry / 大環状デプシペプチド / リボゾーム / 誘導体合成 / 収束的全合成 / 中分子天然物 / PPI / 絶対立体構造 / 創薬研究 / 抗嫌気性菌活性 / Elomgation Factor / 中分子 / 微生物培養 / 絶対立体化学構造 / PPI阻害剤 / 大腸炎治療薬 / 嫌気性菌 / 標的分子因子 / 生体機能分子 / 医薬品創製 / 大村天然物ライブラリー / 生物機能分子ライブラリー / 大村天然化合物リガンド / ケミカルツール分子 / ケミカルバイオロジー / 世界三大感染症 / 抗マラリア薬 / 生物活性リガンド / ケミカルツール / 創薬シード / 網羅的 / 熱帯病 / 顧みられない病気 / 絶対立体構造を決定 / ケトエノール互変異性 / 特異な環状構造 / 熱帯病治療薬 / 向山アルドール反応 / 得意な環状構造 / 向山型ビニロガスアルキル化反応 / 籠状構造 / マクロラクトン化 / アフリカ睡眠病 / 顧みられない熱帯病 / 三次元構造 / アージフィン / 分子設計 / 環状ペプチド / キチナーゼ / ドラックデザイン / Structure determination / Organic chemistry / Bioactive / Infectious disease / Organic synthesis / Antibiotics / ルミナミシン / 収束的合成 / 不斉全合成 / 構造決定 / 有機化学 / 感染症 / Structor Determination / Absolute Stereochemistry / Enantioselective / Stereoselectire / Ligand / Madindoline / Natunal Products / 鍵化学物質 / エナンチオ制御 / 効率的 / 大量合成 / リガンド / エナンチオ選択的 / 短工程 / 不斉リガンド / インターロイキン6 / 微量天然物 / Structure-Activity Relationships / biomimetic / sesquiterpene / Coupling reaction / Total Synthesis / Meroterpenoid / alpha-Pyrone / アリスカシン / メロ-テルぺノイド / セスキテルペン / AchE / 抗トリパノソーマ活性 / 抗マラリア活性 / スピロアミナール / 細胞周期阻害 / グラムスケール / インドリン / ネオキサリン / 抗トリパノソーマ / カスケード / 多環式含窒素化合物 / ドミノ反応 / 実践的合成 / 創薬 / Avermectin / 位置選択的 / ピリジン誘導体 / アシル化 / ポリオール / αーヒドロキシアミド / 有機分子触媒 / イソシア二ド / 位置選択的アシル化 / イソシアニド / ピリドン / 有機触媒 / アルカロイド / Il-6 / 骨粗鬆 / I1-6 / 含窒素化合物 / 分子骨格構築法 / 天然物合成 / 4級炭素 / キレーション / 不斉酸化 / 環状化合物 / 多元素 / アリヌガシン / 化学変換 … More Except Principal Investigator ACAT / 免疫調節作用 / 抗炎症分子 / マクロライド改変体 / リウマチ関節炎 / マクロライド誘導体 / エリスロマイシン / 骨再生 / 骨芽細胞 / 骨免疫学 / 歯周炎 / 破骨細胞 / 骨修復 / 組織再生 / 歯周病治療学 / マクロライド系抗菌薬 / 免疫調節 / 抗炎症 / DEL-1 / 骨免疫 / 骨代謝 / 歯周病 / 癌 / 立体構造解析 / PDK4 / 心不全 / ORIENTAL MEDICINE / INFLUENZA / PINELLIC ACID / AIRWAY INFLAMMATION / PROTEOMIC ANALYSIS / MUCOSAL IMMUNE SYSTEM / SHOSEIRYUTO / KAMPO MEDICINE / 東洋医学 / インフルエンザ / ピネリン酸 / 気道炎症 / プロテオーム解析 / 粘膜免疫 / 小青竜湯 / 漢方薬 / Inhibitor / Biosynthesis / Total synthesis / Structure-activity relationship / Pyripyropene / Fungal metabolite / Acyl-CoA : cholesterol acyltransferase / アシルCoA:コレステロールアシル転移酵素 / 全合成 / アシルCoA:コレスチロールアシル転移酵素 / コレステロール代謝 / CETP / コレステリルエステル転送蛋白質 / 誘導体合成 / コレステロール代謝阻害剤 / 阻害剤 / 生合成 / 金合成 / 構造活性相関 / ピリピロペン / カビ代謝産物 / アシルCoAコレステロールアシル転移酵素 / 培養線維芽細胞 / 好酸球性副鼻腔炎 / エオタキシン / 増強効果 / プライミング効果 / ステロイド / マクロライド / 難治性副鼻腔炎 / ACATアイソザイム / 医療・福祉 / ケミカルバイオロジー / 脂質代謝 / ACAT アイソザイム / 動脈硬化症 Less

Synthesis of the lead compound of PPI inhibitor, DityromycinPrincipal Investigator
- Principal Investigator
  
  Sunazuka Toshiaki
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 33020:Synthetic organic chemistry-related
- Research Institution
  Kitasato University
Therapeutic strategies against inflammation and bone loss associated with Del-1 production
- Principal Investigator
  
  Maekawa Tomoki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Niigata University
Development of a novel PDK4 inhibitor as a new therapeutic agent for heart failure
- Principal Investigator
  
  Nagai Ryozo
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 53:Organ-based internal medicine and related fields
- Research Institution
  Jichi Medical University
Creation of chemical tools and pharmaceuticals leads using Omura natural productsPrincipal Investigator
- Principal Investigator
  
  砂塚敏明
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Research Institution
  Kitasato University
Cascade and efficient total synthesisor for drug discovery of tropical diseasePrincipal Investigator
- Principal Investigator
  
  Sunazuka Toshiaki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kitasato University
Synthetic Strategy for Construction of Unique Polycyclic Indole Alkaloids by cascade reactionsPrincipal Investigator
- Principal Investigator
  
  Sunazuka Toshiaki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kitasato University
Practical Synthesis of Bioactive Natural Products by OrganocatalystsPrincipal Investigator
- Principal Investigator
  
  Sunazuka Toshiaki
- Project Period (FY)
  2011 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  Kitasato University
New therapy for refractory chronic sinusitis in application with priming effect of macrolide on steroid therapy
- Principal Investigator
  
  MATSUNE Shoji
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Nippon Medical School
  Kagoshima University
Total synthesis of novel polycyclic bioactive indole alkaloidsPrincipal Investigator
- Principal Investigator
  
  SUNAZUKA Toshiaki
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kitasato University
ガン調節機能を有する多環式含窒素生体機能分子の実践的合成Principal Investigator
- Principal Investigator
  
  砂塚敏明
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Kitasato University
Discovery and development of selectivity-defined inhibitors toward two acyl-CoA : cholesterol acyltransferase isozymes
- Principal Investigator
  
  TOMODA Hiroshi
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kitasato University
合理的ドラックデザインを駆使した抗感染症薬の創製とマクロライドへの骨格変換Principal Investigator
- Principal Investigator
  
  砂塚敏明
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kitasato University
ガン調節機能を有する多環式含窒素生体機能分子の実践的合成Principal Investigator
- Principal Investigator
  
  砂塚敏明
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Kitasato University
ACTION MECHANISM OF A KAMPO MEDICINE "SHOSEIRYUTO" AGAINST AIRWAY INFECTION AND ITS ACTIVE SUBSTANCE
- Principal Investigator
  
  NAGAI Takayuji
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General internal medicine (including Psychosomatic medicine)
- Research Institution
  Kitasato University
Stereostructure and synthetic study of dilactone macrolide luminamicin, an anaerobic antibioticPrincipal Investigator
- Principal Investigator
  
  SUNAZUKA Toshiaki
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kitasato University
多元素環状化合物の新規分子骨格構築法の開発と天然物合成Principal Investigator
- Principal Investigator
  
  砂塚敏明
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Kitasato University
Efficient Enantioselectine Total Synthesis of Bioactiae natual ProductsPrincipal Investigator
- Principal Investigator
  
  SUNAZAKA Toshiahi
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kitasato University
多官能性α-ピロン環を有するメロ-テルペノイド類の立体選択的合成研究Principal Investigator
- Principal Investigator
  
  砂塚敏明
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kitasato University
多官能性α-ピロン環を有するメロ-テルペノイド類の立体選択的合成研究Principal Investigator
- Principal Investigator
  
  砂塚敏明
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kitasato University
多官能性α-ピロン環を有するメローテルペノイド類の立体選択的合成研究Principal Investigator
- Principal Investigator
  
  砂塚敏明
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kitasato University
Chemical Studies of alpha-Pyrone MeroterpenoidsPrincipal Investigator
- Principal Investigator
  
  SUNAZUKA Toshiaki
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kitasato University
Studies on fungal pyripyropenes, potent inhibitors of cholesterol metabolism
- Principal Investigator
  
  OMURA Satoshi
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Chemical pharmacy
- Research Institution
  The Kitasato Institute

[Book] 微生物由来生物活性天然物の合成と創薬への展開化学と工業2011
- Author(s)
  砂塚敏明
- Data Source
  KAKENHI-PROJECT-21590020
[Journal Article] Structure, solubility, and permeability relationships in a diverse middle molecule library2021
- Author(s)
  Kayoko Kanamitsu et al.
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 37 Pages: 127847-127847
- DOI
  10.1016/j.bmcl.2021.127847
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06586, KAKENHI-PROJECT-19H03345, KAKENHI-PROJECT-19K06965, KAKENHI-PROJECT-21K05059
[Journal Article] Towards the total synthesis of aurodox: preparation of the key hemiacetal-lactone2021
- Author(s)
  Motoyoshi Ohara, Akari Ikeda, Asuka Nakajuma, Takanori Ono, Yoshihiko Noguchi,Akito Watanabe, Tomoyasu Hirose, Toshiaki Sunazuka
- Journal Title
  
  Tetrahedron Letters
  
  Volume: 66 Pages: 152799-152799
- DOI
  10.1016/j.tetlet.2020.152799
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06586, KAKENHI-PROJECT-19K16318, KAKENHI-PROJECT-21K05059
[Journal Article] Pd-catalyzed Regio- and Stereoselective Hydrostannylation of an Alkyl Ethynyl Ether/One-Pot Stille Coupling Enables a Synthesis of 14-Membered Macrolactone of Luminamicin2021
- Author(s)
  Akihiro Sugawara, Hirokazu Takada, Tomoyasu Hirose, Aoi Kimishima, Takeshi Yamada, Masaki Toda, Toru Kojima, Takanori Matsumaru, Toshiaki Sunazuka
- Journal Title
  
  Organic Letters
  
  Volume: 23 Issue: 5 Pages: 1758-1763
- DOI
  10.1021/acs.orglett.1c00183
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06586, KAKENHI-PROJECT-20K05502, KAKENHI-PROJECT-21K05059
[Journal Article] Discoveries and Syntheses of Highly Potent Antimalarial Troponoids2021
- Author(s)
  R. Saito, G. Sennari, A. Nakajima, A. Kimishima, M. Iwatsuki, A. Ishiyama, R. Hokari, T. Hirose, T. Sunazuka.
- Journal Title
  
  Chemical and Pharmaceutical Bulletin
  
  Volume: 69 Issue: 6 Pages: 564-572
- DOI
  10.1248/cpb.c21-00132
- NAID
  130008046495
- ISSN
  0009-2363, 1347-5223
- Year and Date
  2021-06-01
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K05059
[Journal Article] Unified enantioselective total synthesis of 3,6-dioxygenated diketopiperazine natural products, diatretol and lepistamides A, B and C2021
- Author(s)
  Shu Takahashi, Aoi Kimishima, Tomoyasu Hirose, Takeshi Yamada, Akihiro Sugawara, Tatsuya Shirahata, Yoshihiko Noguchi, Masato Iwatsuki, Rei Hokari, Aki Ishiyama, Yoshinori Kobayashi, Toshiaki Sunazuka
- Journal Title
  
  Tetrahedron Letters
  
  Volume: 67 Pages: 152895-152895
- DOI
  10.1016/j.tetlet.2021.152895
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06586, KAKENHI-PROJECT-19K16318, KAKENHI-PROJECT-20K05502, KAKENHI-PROJECT-21K05059
[Journal Article] Trichothioneic acid, a new antioxidant compound produced by the fungal strain Trichoderma virens FKI-75732020
- Author(s)
  Miyano Rei、Matsuo Hirotaka、Mokudai Takayuki、Noguchi Yoshihiko、Higo Mayuka、Nonaka Kenichi、Niwano Yoshimi、Sunazuka Toshiaki、Shiomi Kazuro、Takahashi Yoko、Omura Satoshi、Nakashima Takuji
- Journal Title
  
  Journal of Bioscience and Bioengineering
  
  Volume: 129 Issue: 4 Pages: 508-513
- DOI
  10.1016/j.jbiosc.2019.11.007
- NAID
  40022216167
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-18H04629, KAKENHI-PROJECT-19K16318
[Journal Article] Efficient synthesis of a ryanodine binding inhibitor verticilide using two practical approache2020
- Author(s)
  Watanabe, A., Noguchi, Y., Hirose, T., Monma, S., Satake T., Arai, M., Masuda, K., Murashima, N., Shiomi, R., Omura, S., and Sunazuka, T.
- Journal Title
  
  Tetrahedron Lett.
  
  Volume: 61 Issue: 13 Pages: 151699-151703
- DOI
  10.1016/j.tetlet.2020.151699
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-18H04629, KAKENHI-PROJECT-18K06586, KAKENHI-PROJECT-19K16318
[Journal Article] Kozupeptins, Antimalarial Agents Produced by Paracamarosporium Species: Isolation, Structural Elucidation, Total Synthesis, and Bioactivity2019
- Author(s)
  Hayashi Yumi、Fukasawa Wataru、Hirose Tomoyasu、Iwatsuki Masato、Hokari Rei、Ishiyama Aki、Kanaida Masahiro、Nonaka Kenichi、Take Akira、Otoguro Kazuhiko、Omura Satoshi、Shiomi Kazuro、Sunazuka Toshiaki
- Journal Title
  
  Organic Letters
  
  Volume: 21 Issue: 7 Pages: 2180-2184
- DOI
  10.1021/acs.orglett.9b00483
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08343, KAKENHI-PUBLICLY-18H04629, KAKENHI-PROJECT-16K08174, KAKENHI-PROJECT-18K06586
[Journal Article] Synthesis and insecticidal efficacy of pyripyropene derivatives. Part II-Invention of afidopyropen2019
- Author(s)
  Kimihiko Goto, Ryo Horikoshi, Masaaki Mitomi, Kazuhiko Oyama, Tomoyasu Hirose, Toshiaki Sunazuka and Satoshi Omura
- Journal Title
  
  J. Antibiot.
  
  Volume: 72 Issue: 9 Pages: 661-681
- DOI
  10.1038/s41429-019-0193-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06586, KAKENHI-PUBLICLY-18H04629
[Journal Article] Synthesis of pyripyropene derivatives and their pest-control efficacy2019
- Author(s)
  Kimihiko Goto, Ryo Horikoshi, Satoshi Nakamura, Masaaki Mitomi, Kazuhiko Oyama, Tomoyasu Hirose, Toshiaki Sunazuka, Satoshi Omura
- Journal Title
  
  Journal of Pesticide Science
  
  Volume: 44 Issue: 4 Pages: 255-263
- DOI
  10.1584/jpestics.D19-032
- NAID
  130007748678
- ISSN
  1348-589X, 1349-0923
- Year and Date
  2019-11-20
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06586, KAKENHI-PUBLICLY-18H04629
[Journal Article] Synthesis of the Antimalarial Peptide Aldehyde, a Precursor of Kozupeptin A, Utilizing a Designed Hydrophobic Anchor Molecule2019
- Author(s)
  Yumi Hayashi, Tomoyasu Hirose, Masato Iwatsuki, Satoshi Omura, Toshiaki Sunazuka
- Journal Title
  
  Org. Lett.
  
  Volume: 21 Issue: 20 Pages: 8229-8233
- DOI
  10.1021/acs.orglett.9b02966
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06586, KAKENHI-PUBLICLY-18H04629
[Journal Article] Insecticidal properties of pyripyropene A, a microbial secondary metabolite, against agricultural pests2018
- Author(s)
  Ryo Horikoshi, Kimihiko Goto, Masaaki Miomi, Kazuhiko Oyama, Toshiaki Sunazuka, Satoshi Omura.
- Journal Title
  
  Journal of Pesticide Science
  
  Volume: 43 Issue: 4 Pages: 266-271
- DOI
  10.1584/jpestics.D18-030
- NAID
  130007520014
- ISSN
  1348-589X, 1349-0923
- Year and Date
  2018-11-20
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-18H04629, KAKENHI-PROJECT-16K08174
[Journal Article] Synthesis and evaluation of antibacterial activity of bottromycins2018
- Author(s)
  Takeshi Yamada, Miu Yagita, Yutaka Kobayashi, Goh Sennari, Hiroyuki Shimamura, Hidehito Matsui, Yuki Horimatsu, Hideaki Hanaki, Tomoyasu Hirose, Satoshi Omura, Toshiaki Sunazuka
- Journal Title
  
  Journal of Organic Chemistry
  
  Volume: 83 Issue: 13 Pages: 7135-7149
- DOI
  10.1021/acs.joc.8b00045
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08219, KAKENHI-PROJECT-18K06586, KAKENHI-PUBLICLY-18H04629, KAKENHI-PROJECT-16K08174
[Journal Article] Jietacins, azoxy antibiotics with potent nematocidal activity: Design, synthesis, and biological evaluation against parasitic nematodes2018
- Author(s)
  Sugawara Akihiro、Kubo Masahiko、Hirose Tomoyasu、Yahagi Kyoichi、Tsunoda Noriaki、Noguchi Yoshihiko、Nakashima Takuji、Takahashi Yoko、Welz Claudia、Mueller Dennis、Mertens Christina、Koebberling Johannes、?mura Satoshi、Sunazuka Toshiaki
- Journal Title
  
  European Journal of Medicinal Chemistry
  
  Volume: 145 Pages: 524-538
- DOI
  10.1016/j.ejmech.2017.12.031
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08174, KAKENHI-PROJECT-18K06586
[Journal Article] Pestynol, a novel antifungal compound discovered using a Saccharomyces cerevisiae 12geneΔ0HSR-iERG6-based assay2018
- Author(s)
  Katsuyuki Sakai, Tomoyasu Hirose, Masato Iwatsuki, Takumi Chinen, Toru Kimura, Takuya Suga, Kenichi Nonaka, Takuji Nakashima, Toshiaki Sunazuka, Takeo Usui, Yukihiro Asami, Satoshi Omura, Kazuro Shiomi
- Journal Title
  
  J. Nat. Prod.
  
  Volume: 81 Issue: 7 Pages: 1604-1609
- DOI
  10.1021/acs.jnatprod.8b00200
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06586, KAKENHI-PUBLICLY-18H04629, KAKENHI-PROJECT-16K08174
[Journal Article] Synthesis and insecticidal efficacy of pyripyropene derivatives focusing on the C-1, C-7, and C-11 positions' substituent groups2018
- Author(s)
  Kimihiko Goto, Ryo Horikoshi, Masaaki Mitomi, Kazuhiko Oyama, Tomoyasu Hirose, Toshiaki Sunazuka, Satoshi Omura
- Journal Title
  
  J. Antibiot.
  
  Volume: 72 Issue: 9 Pages: 785-797
- DOI
  10.1038/s41429-018-0064-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06586, KAKENHI-PUBLICLY-18H04629, KAKENHI-PROJECT-16K08174
[Journal Article] Naphthacemycins, novel circumventors of β-lactam resistance in MRSA, produced by Streptomyces sp. KB-3346-5. II. Structure elucidation.2017
- Author(s)
  Atsushi Fukumoto, Yong-Pil Kim, Masato Iwatsuki, Tomoyasu Hirose, Toshiaki Sunazuka, Hideaki Hanaki, Satoshi Omura and Kazuro Shiomi.
- Journal Title
  
  J. Antibiot.
  
  Volume: 70 Issue: 5 Pages: 568-573
- DOI
  10.1038/ja.2017.29
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08174, KAKENHI-PROJECT-15K07866
[Journal Article] Total Synthesis and Determination of the Absolute Configuration of Naturally Occurring Mangromicin A, with Potent Antitrypanosomal Activity2017
- Author(s)
  Hirokazu Takada, Takeshi Yamada, Tomoyasu Hirose, Takuma Ishihara, Takuji Nakashima, Yoko Takahashi, Satoshi Omura, Toshiaki Sunazuka
- Journal Title
  
  Organic Letters
  
  Volume: 19 Issue: 1 Pages: 230-233
- DOI
  10.1021/acs.orglett.6b03512
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18836, KAKENHI-PROJECT-15K07866, KAKENHI-PROJECT-16K08174
[Journal Article] Stereo- and substituent-enabled divergent synthesis of 5,6-spiroketal analogs of avermectin containing a triazole function.2017
- Author(s)
  Takeshi Yamada, Yuki Horimatsu, Tomoyasu Hirose, Akihiro Sugawara, Satoshi Omura and Toshiaki Sunazuka.
- Journal Title
  
  Tetrahedron Lett. 58
  
  Volume: 58 Issue: 32 Pages: 3119-3124
- DOI
  10.1016/j.tetlet.2017.06.072
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08174, KAKENHI-PROJECT-17K08219, KAKENHI-PROJECT-15K07866
[Journal Article] Total synthesis of (±)-naphthacemycin A9, possessing both antibacterial activity against methicillin-resistant Staphylococcus aureus and circumventing effect of β-lactam resistance.2017
- Author(s)
  Tomoyasu Hirose, Yasuhiro Kojima, Hidehito Matsui, Hideaki Hanaki, Masato Iwatsuki, Kazuro Shiomi, Satoshi Omura and Toshiaki Sunazuka
- Journal Title
  
  J. Antibiot.
  
  Volume: 70 Issue: 5 Pages: 574-581
- DOI
  10.1038/ja.2016.141
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08174, KAKENHI-PROJECT-15K07866
[Journal Article] Toward the total synthesis of luminamicin; an anaerobic antibiotic: construction of highly functionalized cis-decalin containing a bridged ether moiety.2017
- Author(s)
  Hiroyasu Ando, Aoi Kimishima, Motoyoshi Ohara, Tomoyasu Hirose, Takanori Matsumaru, Hirokazu Takada, Keisuke Morodome, Takehiro Miyamoto, Akihiro Sugawara, Satoshi Omura and Toshiaki Sunazuka
- Journal Title
  
  J. Antibiot.
  
  Volume: 71 Issue: 2 Pages: 268-272
- DOI
  10.1038/ja.2017.77
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08174, KAKENHI-PROJECT-16K08175, KAKENHI-PROJECT-15K07866
[Journal Article] Towards the total synthesis of the anti-trypanosomal macrolide, Actinoallolides; construction of a key linear intermediate2016
- Author(s)
  Jun Oshita, Yoshihiko Noguchi, Akito Watanabe, Goh Sennari, Shogo Sato, Tomoyasu Hirose, Daiki Oikawa, Yuki Inahashi, Masato Iwatsuki, Aki Ishiyama, Satoshi Omura and Toshiaki Sunazuka
- Journal Title
  
  Tetrahedron Lett.
  
  Volume: 57 Pages: 357-360
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-23105012
[Journal Article] Towards the total synthesis of the anti-trypanosomal macrolide, Actinoallolides: construction of a key linear intermediate2016
- Author(s)
  Jun Oshita, Yoshihiko Noguchi, Akito Watanabe, Goh Sennari, Shogo Sato, Tomoyasu Hirose, Daiki Oikawa, Yuki Inahashi, Masato Iwatsuki, Aki Ishiyama, Satoshi Omura and Toshiaki Sunazuka
- Journal Title
  
  Tetrahedron Lett.
  
  Volume: 57 Issue: 3 Pages: 357-360
- DOI
  10.1016/j.tetlet.2015.12.022
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07866, KAKENHI-PROJECT-15J10769, KAKENHI-PROJECT-16K08174
[Journal Article] Organocatalytic Site-Selective Acylation of Avermectin B<sub>2a</sub>, a Unique Endectocidal Drug2016
- Author(s)
  Takeshi Yamada, Koh Suzuki, Tomoyasu Hirose, Takumi Furuta, Yoshihiro Ueda, Takeo Kawabata, Satoshi Omura and Toshiaki Sunazuka
- Journal Title
  
  Chemical and Pharmaceutical Bulletin
  
  Volume: 64 Issue: 7 Pages: 856-864
- DOI
  10.1248/cpb.c16-00205
- NAID
  130005160046
- ISSN
  0009-2363, 1347-5223
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-23105012, KAKENHI-PUBLICLY-16H01148, KAKENHI-PROJECT-26221301, KAKENHI-PROJECT-15K18827, KAKENHI-PROJECT-15K07866
[Journal Article] Organocatalytic Site-Selective Acylation of Avermectin B2a, a Unique Endectocidal Drug2016
- Author(s)
  Takeshi Yamada, Koh Suzuki, Tomoyasu Hirose, Takumi Furuta, Yoshihiro Ueda, Takeo Kawabata, Satoshi Omura and Toshiaki Sunazuka
- Journal Title
  
  Chem. Pharm. Bull
  
  Volume: 64 Pages: 856-864
- NAID
  130005160046
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08174
[Journal Article] Towards the total synthesis of the anti-trypanosomal macrolide, Actinoallolides; construction of a key linear intermediate2016
- Author(s)
  Jun Oshita, Yoshihiko Noguchi, Akito Watanabe, Goh Sennari, Shogo Sato, Tomoyasu Hirose, Daiki Oikawa, Yuki Inahashi, Masato Iwatsuki, Aki Ishiyama, Satoshi Omura and Toshiaki Sunazuka
- Journal Title
  
  Tetrahedron Lett.
  
  Volume: 57 Pages: 357-360
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25460020
[Journal Article] Organocatalytic Site-Selective Acylation of 10-Deacetylbaccatin III2016
- Author(s)
  Yanagi Masanori, Ryo Ninomiya, Yoshihiro Ueda, Takumi Furuta, Takeshi Yamada, Toshiaki Sunazuka, Takeo Kawabata
- Journal Title
  
  Chemical and Pharmaceutical Bulletin
  
  Volume: 64 Issue: 7 Pages: 907-912
- DOI
  10.1248/cpb.c16-00037
- NAID
  130005160042
- ISSN
  0009-2363, 1347-5223
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18827, KAKENHI-PLANNED-23105008, KAKENHI-PLANNED-23105012, KAKENHI-PROJECT-26221301, KAKENHI-PROJECT-15K18836, KAKENHI-PROJECT-16K08174
[Journal Article] The Design, Synthesis, and Evaluation of 1,5,7-Trisubstituted-3-Pyridyl-Xanthones for Use as Insecticides Starting from Pyripyropene A2016
- Author(s)
  Shinichiro Fuse, Keisuke Matsumura, Kohei Johmoto, Hidehiro Uekusa, Hiroshi Tanaka, Tomoyasu Hirose, Toshiaki Sunazuka, Satoshi Omura, Takashi Takahashi
- Journal Title
  
  Chem. Eur. J.
  
  Volume: 51 Issue: 51 Pages: 18450-18455
- DOI
  10.1002/chem.201603980
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07866, KAKENHI-PROJECT-16K08174
[Journal Article] Asymmetric Total Synthesis of Indole Alkaloids Containing An Indoline Spiroaminal Framework2015
- Author(s)
  Takeshi Yamada, Tetsuya Ideguchi-Matsushita, Tomoyasu Hirose, Tatsuya Shirahata, Rei Hokari, Aki Ishiyama, Masato Iwatsuki, Akihiro Sugawara, Yoshinori Kobayashi, Kazuhiko Otoguro, Satoshi Omura and Toshiaki Sunazuka
- Journal Title
  
  Chem. E. J.
  
  Volume: 21 Pages: 11855-11864
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25460020
[Journal Article] Actinoallolides A–E, New Anti-trypanosomal Macrolides, Produced by an Endophytic Actinomycete, Actinoallomurus fulvus MK10-036.2015
- Author(s)
  Yuki Inahashi, Masato Iwatsuki, Aki Ishiyama, Atsuko Matsumoto, Tomoyasu Hirose, Jun Oshita, Toshiaki Sunazuka, Watanalai Panbangred, Yoko Takahashi, Marcel Kaiser, Kazuhiko Otoguro and Satoshi Omura
- Journal Title
  
  Org. Lett.
  
  Volume: 17 Pages: 864-867
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23105012
[Journal Article] Jietacins with potent nematocidal activity; efficient isolation of novel analogues and divergent total synthesis of jietacin A, B, C, and D.2015
- Author(s)
  Akihiro Sugawara, Masahiko Kubo, Takuji Nakashima, Tomoyasu Hirose, Noriaki Tsunoda, Kyoichi Yahagi, Yukihiro Asami, Takeshi Yamada, Kazuro Shiomi, Yoko Takahashi, Satoshi Omura and Toshiaki Sunazuka
- Journal Title
  
  Tetrahedron
  
  Volume: 71 Pages: 2149-2157
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23105012
[Journal Article] Asymmetric Total Synthesis of Indole Alkaloids Containing An Indoline Spiroaminal Framework.2015
- Author(s)
  Takeshi Yamada, Tetsuya Ideguchi-Matsushita, Tomoyasu Hirose, Tatsuya Shirahata, Rei Hokari, Aki Ishiyama, Masato Iwatsuki, Akihiro Sugawara, Yoshinori Kobayashi, Kazuhiko Otoguro, Satoshi Omura and Toshiaki Sunazuka
- Journal Title
  
  Chem. E. J.
  
  Volume: 21 Pages: 11855-11864
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-23105012
[Journal Article] Creation of customised bioactivity within a 14-membered macrolide scaffold: design, synthesis, and biological evaluation using a family-18 chitinase.2015
- Author(s)
  Akihiro Sugawara, Nobuo Maita, Hiroaki Gouda, Tsuyoshi Yamamoto, Tomoyasu Hirose, Saori Kimura, Yoshifumi Saito, Hayato Nakano, Takako Kasai, Hirofumi Nakano, Kazuro Shiomi, Shuichi Hirono, Takeshi Watanabe, Hisaaki Taniguchi, Satoshi Omura and Toshiaki Sunazuka
- Journal Title
  
  J. Med. Chem.
  
  Volume: 58 Pages: 4984-4997
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25460020
[Journal Article] Creation of customised bioactivity within a 14-membered macrolide scaffold: design, synthesis, and biological evaluation using a family-18 chitinase.2015
- Author(s)
  Akihiro Sugawara, Nobuo Maita, Hiroaki Gouda, Tsuyoshi Yamamoto, Tomoyasu Hirose, Saori Kimura, Yoshifumi Saito, Hayato Nakano, Takako Kasai, Hirofumi Nakano, Kazuro Shiomi, Shuichi Hirono, Takeshi Watanabe, Hisaaki Taniguchi, Satoshi Omura and Toshiaki Sunazuka
- Journal Title
  
  J. Med. Chem.
  
  Volume: 58 Pages: 4984-4997
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-23105012
[Journal Article] Jietacins with potent nematocidal activity; efficient isolation of novel analogues and divergent total synthesis of jietacin A, B, C, and D2015
- Author(s)
  4) Akihiro Sugawara, Masahiko Kubo, Takuji Nakashima, Tomoyasu Hirose, Noriaki Tsunoda, Kyoichi Yahagi, Yukihiro Asami, Takeshi Yamada, Kazuro Shiomi, Yoko Takahashi, Satoshi Omura, Toshiaki Sunazuka
- Journal Title
  
  Tetrahedron
  
  Volume: 71 Issue: 14 Pages: 2149-2157
- DOI
  10.1016/j.tet.2015.02.038
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590019, KAKENHI-PROJECT-25460020, KAKENHI-PROJECT-26860015, KAKENHI-PROJECT-15K07866, KAKENHI-PROJECT-15K18836
[Journal Article] An architectonic macrolide library based on a C2-symmetric macrodiolide toward pharmaceutical compositions.2015
- Author(s)
  Hayato Nakano, Akihiro Sugawara, Tomoyasu Hirose, Hiroaki Gouda, Shuichi Hirono, Satoshi Omura and Toshiaki Sunazuka
- Journal Title
  
  Tetrahedron
  
  Volume: 71 Issue: 37 Pages: 000-000
- DOI
  10.1016/j.tet.2015.01.030
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23105012, KAKENHI-PROJECT-24590019, KAKENHI-PROJECT-25460020, KAKENHI-PUBLICLY-26102737
[Journal Article] Organocatalytic α-Addition of Isocyanides to Aldehydes2015
- Author(s)
  Takeshi Yamada, Tomoyasu Hirose, Satoshi Omura and Toshiaki Sunazuka
- Journal Title
  
  Eur. J. Org. Chem.
  
  Volume: 2015 Issue: 2 Pages: 296-301
- DOI
  10.1002/ejoc.201403313
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23105012, KAKENHI-PROJECT-24590019, KAKENHI-PROJECT-25460020, KAKENHI-PROJECT-25860010, KAKENHI-PROJECT-15K18836
[Journal Article] Leucomycin A3, a 16-membered macrolide antibiotic, inhibits influenza A virus infection and disease progression2014
- Author(s)
  Ryuichi Sugamata, Akihiro Sugawara, Tomokazu Nagao, Koya Suzuki, Tomoyasu Hirose, Ki-ichi Yamamoto, Masamichi Oshima, Kazuo Kobayashi, Toshiaki Sunazuka, Kiyoko S Akagawa, Satoshi Omura, Toshinori Nakayama, Kazuo Suzuki
- Journal Title
  
  J Antibiot
  
  Volume: 67 Pages: 213-222
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23105012
[Journal Article] A concise total synthesis of puberulic acid, a potent antimalarial agent.2014
- Author(s)
  Goh Sennari, Tomoyasu Hirose, Masato Iwatsuki, Satoshi Omura and Toshiaki Sunazuka
- Journal Title
  
  Chem. Commun.
  
  Volume: 50 Pages: 8715-8718
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23105012
[Journal Article] Leucomycin A3, a 16-membered macrolide antibiotic, inhibits influenza A virus infection and disease progression2014
- Author(s)
  Ryuichi Sugamata, Akihiro Sugawara, Tomokazu Nagao, Koya Suzuki, Tomoyasu Hirose, Ki-ichi Yamamoto, Masamichi Oshima, Kazuo Kobayashi, Toshiaki Sunazuka, Kiyoko S Akagawa, Satoshi Omura, Toshinori Nakayama, Kazuo Suzuki
- Journal Title
  
  J Antibiot
  
  Volume: 67 Pages: 213-222
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460020
[Journal Article] Leucomycin A3, a 16-membered macrolide antibiotic, inhibits influenza A virus infection and disease progression.2014
- Author(s)
  Ryuichi Sugamata, Akihiro Sugawara, Tomokazu Nagao, Koya Suzuki, Tomoyasu Hirose, Ki-ichi Yamamoto, Masamichi Oshima, Kazuo Kobayashi, Toshiaki Sunazuka, Kiyoko S Akagawa, Satoshi Omura, Toshinori Nakayama and Kazuo Suzuki
- Journal Title
  
  J. Antibiot.
  
  Volume: 67 Pages: 213-222
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23105012
[Journal Article] Asymmetric total synthesis of neoxaline2013
- Author(s)
  Tetsuya Ideguchi, Takeshi Yamada, Tatsuya Shirahata, Tomoyasu Hirose, Akihiro Sugawara, Yoshinori Kobayashi, Satoshi Omura, Toshiaki Sunazuka
- Journal Title
  
  J Am Chem Soc
  
  Volume: 135 Issue: 34 Pages: 12568-12571
- DOI
  10.1021/ja406657v
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23105012, KAKENHI-PUBLICLY-24102527, KAKENHI-PROJECT-24790021, KAKENHI-PROJECT-24790022, KAKENHI-PROJECT-25460020, KAKENHI-PROJECT-25860010
[Journal Article] Human acidic mammalian chitinase as a novel target for anti-asthma drug design using in silico screening2013
- Author(s)
  Masaki Wakasugi, Hiroaki Gouda, Tomoyasu Hirose, Akihiro Sugawara, Tsuyoshi Yamamoto, Kazuro Shiomi, Toshiaki Sunazuka, Satoshi Omura, Shuichi Hirono
- Journal Title
  
  Bioorg Med Chem
  
  Volume: 21 Issue: 11 Pages: 3214-3220
- DOI
  10.1016/j.bmc.2013.03.047
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23105012, KAKENHI-PUBLICLY-24102527, KAKENHI-PROJECT-24590058, KAKENHI-PROJECT-24790022, KAKENHI-PROJECT-25460020
[Journal Article] Observation of the controlled assembly of preclick components in the in situ click chemistry generation of a chitinase inhibitor2013
- Author(s)
  Hirose T, Maita N, Taniguchi H, Sharpless KB, Omura S, Sunazuka T
- Journal Title
  
  Proc.Natl.Acad.Sci. USA.
  
  Volume: 110 Issue: 40 Pages: 15892-15897
- DOI
  10.1073/pnas.1315049110
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22370042, KAKENHI-PLANNED-23105012, KAKENHI-PROJECT-23570139, KAKENHI-PUBLICLY-24102527, KAKENHI-PROJECT-24580104, KAKENHI-PROJECT-24590058, KAKENHI-PROJECT-24790022, KAKENHI-PROJECT-25460020
[Journal Article] Borrelidin analogues with antimalarial activity: design, synthesis and biological evaluation against Plasmodium falciparum parasites2013
- Author(s)
  Akihiro Sugawara, Toshiaki Tanaka, Tomoyasu Hirose, Aki Ishiyama, Masato Iwatsuki, Yoko Takahashi, Kazuhiko Otoguro, Satoshi Omura, Toshiaki Sunazuka
- Journal Title
  
  Bioorg Med Chem Lett
  
  Volume: 23 Issue: 8 Pages: 2302-2305
- DOI
  10.1016/j.bmcl.2013.02.075
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23105012, KAKENHI-PUBLICLY-24102527, KAKENHI-PROJECT-24790022, KAKENHI-PROJECT-25460020
[Journal Article] Novel 12-membered non-antibiotic macrolides, EM900 series with anti-inflammatory and/or immunomodulatory activity; synthesis, structure?activity relationships and in vivo study2012
- Author(s)
  Akihiro Sugawara, Akito Sueki, Tomoyasu Hirose, Hideaki Shima, Kiyoko S Akagawa, Satoshi?mura and Toshiaki Sunazuka
- Journal Title
  
  J. Antibiot.
  
  Volume: 65 Issue: 9 Pages: 487-490
- DOI
  10.1038/ja.2012.51
- NAID
  10031044227
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790022, KAKENHI-PLANNED-23105012, KAKENHI-PUBLICLY-24102527
[Journal Article] The first total synthesis and reassignment of the relative stereochemistry of 16-hydroxy-16, 22-dihydroapparicine2012
- Author(s)
  Noguchi, Y.; Hirose, T.; Furuya, Y.; Ishiyama, A.; Otoguro, K.; Omura, S.; Sunazuka, T.
- Journal Title
  
  Tetrahedron Lett
  
  Volume: 53(14) Issue: 14 Pages: 1802-1807
- DOI
  10.1016/j.tetlet.2012.01.110
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590020, KAKENHI-PROJECT-22790017, KAKENHI-PLANNED-23105012
[Journal Article] Toward the total synthesis of Luminamicin : construction of 14-membered lactone framework possessing versatile enol ether moiety2012
- Author(s)
  Aoi Kimishima, Tomoyasu Hirose, Akihiro Sugawara, Takanori Matsumaru, Kaoru Nakamura, Ken Katsuyama, Masaki Toda, Hirokazu Takada, Rokuro Masuma, Satoshi?mura, Toshiaki Sunazuka
- Journal Title
  
  Tetrahedron Lett.
  
  Volume: 53 Issue: 23 Pages: 2813-2816
- DOI
  10.1016/j.tetlet.2012.03.098
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790022, KAKENHI-PLANNED-23105012, KAKENHI-PUBLICLY-24102527
[Journal Article] Boromycin derivatives : synthesis and antimalarial activity in vitro and in vivo2010
- Author(s)
  砂塚敏明
- Journal Title
  
  Heterocycles
  
  Volume: 82 Pages: 289-295
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590020
[Journal Article] Bottromycin derivatives : efficient chemical modifications of the ester moiety and evaluation of anti-MRSA and anti-VRE activities.2010
- Author(s)
  砂塚敏明
- Journal Title
  
  Bioorg.Med.Chem.Lett.
  
  Volume: 20 Pages: 6116-6120
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590020
[Journal Article] Chitinase inhibitors : extraction of the active framework from natural argifin and use of in situ click chemistry2009
- Author(s)
  Toshiaki Sunazuka
- Journal Title
  
  The Journal of Antibiotics 62
  
  Pages: 1-6
- NAID
  10030635298
- Data Source
  KAKENHI-PROJECT-18590015
[Journal Article] Argifin ; efficient solid phase total synthesis and evalution of analogues of acyclic peptide2009
- Author(s)
  Toshiaki Sunazuka
- Journal Title
  
  Bioorganic & Medicinal Chemistry 17
  
  Pages: 2751-2758
- Data Source
  KAKENHI-PROJECT-18590015
[Journal Article] The selectivity of beauveriolide derivatives in inhibition toward the two isozymes of acyl-CoA2009
- Author(s)
  Ohshiro T, Matsuda D, Nagai K, Doi T, Sunazuka T, Takahashi T, Rudel LL, Omura S, Tomoda H.
- Journal Title
  
  cholesterol acyltransferase . Chem. Pharm. Bull 57
  
  Pages: 377-381
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390008
[Journal Article] Synthesis and biological evaluation of a focused library of beauveriolides2008
- Author(s)
  Nagai K, Doi T, Ohshiro T, Sunazuka T, Tomoda H, Takahashi T, Omura S.
- Journal Title
  
  Bioorg. Med. Chem. Lett. 18
  
  Pages: 4397-4400
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390008
[Journal Article] Computational analysis of the binding affinities of the natural-product cyclopentapeptides argifin and argadin to chitinase B from Serratia marcescens2008
- Author(s)
  Toshiaki Sunazuka
- Journal Title
  
  Bioorganic & Medicinal Chemistry 16
  
  Pages: 3565-3579
- Data Source
  KAKENHI-PROJECT-18590015
[Journal Article] Selectivity of pyripyropene derivatives in inhibition toward acyl-CoA : cholesterol acyltransferase 2 isozyme2008
- Author(s)
  Ohshiro T, Ohte S, Matsuda D, Ohtawa M, Nagamitsu T, Sunazuka T, Harigaya Y, Rudel LL, Omura S, Tomoda H.
- Journal Title
  
  J. Antibiot 61
  
  Pages: 503-508
- NAID
  10021928313
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390008
[Journal Article] Efficient Total Synthesis of Novel Bioactive Microbial Metabolites2008
- Author(s)
  砂塚敏明
- Journal Title
  
  Accounts for Chemical Research 41
  
  Pages: 302-314
- Data Source
  KAKENHI-PROJECT-18032066
[Journal Article] Computational Analysis of the Binding Affinities of the Natural Product Cyclopentapeptides Argifin and Agadin to Chitinase B2008
- Author(s)
  砂塚敏明
- Journal Title
  
  Biooragnic Medicinal Chemistry 16(In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590015
[Journal Article] Design and Synthesis via Click Chemistry of 8,9-Anhydroerythromycin A 6,9-Hemiketal Analogues with anti-MRSA and VRE Activity2007
- Author(s)
  砂塚敏明
- Journal Title
  
  Biooragnic Medicinal Chemistry Letters 17
  
  Pages: 6340-6344
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590015
[Journal Article] Total Synthesis and Biological Evaluation of Verticipyrone and Anglogues2007
- Author(s)
  砂塚敏明
- Journal Title
  
  Organic Letters 9
  
  Pages: 65-67
- Data Source
  KAKENHI-PROJECT-18032066
[Journal Article] Studies toward the total synthesis of irumamycin : stereoselective preparation of the C(15)-C(27) segment via two-directional chain synthesis2007
- Author(s)
  砂塚敏明
- Journal Title
  
  Tetrahedron Letters 48
  
  Pages: 413-416
- Data Source
  KAKENHI-PROJECT-18032066
[Journal Article] Synthesis of The Oxa-bridged Octalin System of Two Anti-anaerobe Antibiotics,Luminamicin and Lustromycin2007
- Author(s)
  砂塚敏明
- Journal Title
  
  Tetrahedron Letters 48
  
  Pages: 5297-5300
- Data Source
  KAKENHI-PROJECT-18032066
[Journal Article] 抗炎症作用を有する新規マクロライドEM900シリーズ2007
- Author(s)
  砂塚敏明
- Journal Title
  
  J.Antibiotics, Jpn.Suppl. 60
  
  Pages: 39-43
- Data Source
  KAKENHI-PROJECT-18590015
[Journal Article] Total synthesis, elucidation of absolute stereochemistry, and adjuvant activity of trihydroxy fatty acids.2006
- Author(s)
  T. Shirahata, T. Sunazuka, K. Yoshida, D. Yamamoto, Y. Harigaya, I. Kuwajima, T. Nagai, H. Kiyohara, H. Yamada, S. Omura
- Journal Title
  
  Tetrahedron 62 (40)
  
  Pages: 9483-9496
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590601
[Journal Article] Rapid 'SAR' via click chemistry : an alkyne-bearing spiramycin is fused with diverse azides to vield new triazole-antibacterial candidates2006
- Author(s)
  砂塚敏明
- Journal Title
  
  Heterocycles 69
  
  Pages: 55-61
- Data Source
  KAKENHI-PROJECT-18590015
[Journal Article] Synthetic applications of a three-component Mannich reaction. Total synthesis of IL-6 inhibitor(+)-madindoline A and B2006
- Author(s)
  砂塚敏明
- Journal Title
  
  Tetrahedron Letters 47
  
  Pages: 6761-6764
- Data Source
  KAKENHI-PROJECT-18032066
[Journal Article] A Concise Stereoselective Route to the Indoline Spiroaminal Framework of Neoxaline and Oxaline2005
- Author(s)
  砂塚敏明
- Journal Title
  
  Organic Letter 7
  
  Pages: 941-943
- Data Source
  KAKENHI-PROJECT-17035074
[Journal Article] Total Synthesis of (+)-Madinaoline A ana (-)-Madinaoline B, Potent Inhibitors of Interleukin 62005
- Author(s)
  砂塚敏明
- Journal Title
  
  Tetrahedron 61
  
  Pages: 3396-3403
- Data Source
  KAKENHI-PROJECT-17035074
[Journal Article] Stereostructure of luminamicin, an anaerobic antibiotic, via molecular dynamics, NMR spectroscopy, and the modified Mosher method2005
- Author(s)
  砂塚敏明
- Journal Title
  
  Proceeding of the National Academy of Sciences of United States of America 51
  
  Pages: 18286-18291
- Data Source
  KAKENHI-PROJECT-16590012
[Journal Article] Intranasally and orally effective adjuvants from Chinese and Japanese medicinal herbs for nasal influenza vaccine.2005
- Author(s)
  T. Nagai, H. Kiyohara, T. Sunazuka, S. Omura, H. Yamada
- Journal Title
  
  Quality, Efficacy, Safety, Processing and Trade in Medicinal and Aromatic Plants, Acta Horticulturae, (Eds E. Brovelli et al), ISHS, Belgium No. 679
  
  Pages: 121-129
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590601
[Journal Article] Efficient Asymmetric Synthesis of (+)-Physovenine2005
- Author(s)
  砂塚敏明
- Journal Title
  
  Tetrahedron Letter 46
  
  Pages: 1459-1461
- Data Source
  KAKENHI-PROJECT-17035074
[Journal Article] Stereostructure of luminamicin, an anaerobic antibiotic, via molecular dynamics, NMR spectroscopy, and the modified Mosher mehod2005
- Author(s)
  Gouda, H., Sunazuka, T., Handa, M., Ui, H., Yamamoto, D., Monma, S., Hirono, H., Omura, S.
- Journal Title
  
  Proc.Natl, Acad.Sci.USA 102
  
  Pages: 18286-18291
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590012
[Journal Article] Stereostructure of luminamicin, an anaerobic antibiotic, via molecular dynamics, NMR spectroscopy, and the modified Mosher mehod2005
- Author(s)
  砂塚敏明
- Journal Title
  
  Proceeding of the National Academy of Sciences of United States of America 102
  
  Pages: 18286-18291
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590012
[Journal Article] Total Syntheses of the AchE Inhibitors (±)-Arisugacius F and G2003
- Author(s)
  砂塚敏明
- Journal Title
  
  Journal of Autibiotics 56
  
  Pages: 730-733
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12672061
[Journal Article] Total Synthesis of the AchE Inhibitors (±)-Arisugacins F and G2003
- Author(s)
  Handa, M., Sunazuka, T., Sugawara, M., Harigaya, Y., Omura, S.
- Journal Title
  
  J.Antibiot. 56
  
  Pages: 725-726
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12672061
[Journal Article] A Short Total Synthesis of (+)-Madindoline A and B2002
- Author(s)
  砂塚敏明
- Journal Title
  
  Organic Letters 4
  
  Pages: 501-503
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12672061
[Journal Article] The First Total Synthesis of (±)Arisugacin A,A Potent, Orally Inbibitor of Acetylcholinesterase2002
- Author(s)
  砂塚敏明
- Journal Title
  
  Organic Letters 4
  
  Pages: 367-369
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12672061
[Journal Article] A Short Total Synthesis of (+)-Madindoline A and B2002
- Author(s)
  Sunazuka, T., Hirose, T., Shirahata, T., Yamamoto, D., Harigaya, Y., Kuwajima, I., Omura., S.
- Journal Title
  
  Organic Letters. 4
  
  Pages: 501-503
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12672061
[Journal Article] The First Total Synthesis of (±)Arisugacin A, A Potent, Orally Inhibitor of Acetylcholinesterase2002
- Author(s)
  Sunazuka, T., Handa, M., Nagai, K., Shirahata, T., Otoguro, K., Harigaya, Y., Kuwajima, I., Omura, S.
- Journal Title
  
  Organic Letters. 4
  
  Pages: 367-369
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12672061
[Journal Article] Convergent Synthesis of Arisugacin Skekleton and Their Acetylcholinesterase Inhibitor2001
- Author(s)
  砂塚敏明
- Journal Title
  
  Journal of Antibiotics 54
  
  Pages: 382-385
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12672061
[Journal Article] Convergent Synthesis of Arisugacin Skekleton and Their Acetylcholinesterase Inhibitor2001
- Author(s)
  Sunazuka, T., Handa, M., Nagai, K., Kimura, R., Shirahata, T., Tian, Z-M., Otoguro, K., Harigaya, Y., Omura, S.
- Journal Title
  
  J.Antibiotics. 54
  
  Pages: 382-385
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12672061
[Journal Article] Otoguro, K., Harigaya, Y., and Omura, S.2001
- Author(s)
  Sunazuka, T., Handa, M., Nagai, K., Kimura, R., Shirahata, T., Tian, Z-M.
- Journal Title
  
  Determination of Absolute Stereochemistries of Arisugacin F, and Territrem B 54
  
  Pages: 386-391
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12672061
[Journal Article] Determination of Absolute Stereochemistries of Arisugacin F, and Territrem B2001
- Author(s)
  砂塚敏明
- Journal Title
  
  Journal of Antibiotics 54
  
  Pages: 386-391
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12672061
[Journal Article] Total Synthesis of (+)-Madindoline A and (-)-Madindoline B, Potent Inhibitors of Interleukin 62000
- Author(s)
  砂塚敏明
- Journal Title
  
  Journal of American Chemistry Society 122
  
  Pages: 2122-2123
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12672061
[Journal Article] Arisugacins C and D. Novel Acetylcholinesurase inhibitors aad Their Related Novel Matabolites2000
- Author(s)
  砂塚敏明
- Journal Title
  
  Journal of Antibiotics 53
  
  Pages: 52-60
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12672061
[Journal Article] Arisugacins C and D, Novel Acetylcholinesterase inhibitors and Their Related Novel Matabolites2000
- Author(s)
  Otoguro, K., Sunazuka, T., Omura, S.
- Journal Title
  
  J.Antibiotics 53
  
  Pages: 52-60
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12672061
[Journal Article] Total Synthesis of (+)-Madindoline A and (-)-Madindoline B, Potent Inhibitors of Interleukin 62000
- Author(s)
  Sunazuka, T., Hirose, T., Shirahata, T., Harigaya, Y., Hayashi, M., Komiyama, K., Omura, S.
- Journal Title
  
  J.Am.Chem.Soc. 122
  
  Pages: 2122-2123
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12672061
[Patent] 脂肪酸を構成成分とするワクチン製剤2006
- Inventor(s)
  山田陽城清原寛章永井隆之砂塚敏明
- Industrial Property Rights Holder
  社団法人北里研究所
- Acquisition Date
  2006-01-21
- Description
  「研究成果報告書概要(和文)」より
- Overseas
- Data Source
  KAKENHI-PROJECT-17590601
[Presentation] 新規PPI阻害剤創製を指向した中分子天然物ジチロマイシンの全合成研究- 1 -高度に酸素官能基化された非天然アミノ酸骨格の構築-2023
- Author(s)
  鈴木大貴、金井田將裕、野口吉彦、廣瀬友靖、砂塚敏明
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-21K05059
[Presentation] 新規PPI阻害剤創製を指向した中分子天然物ジチロマイシンの全合成研究2023
- Author(s)
  鈴木大貴、金井田將裕、野口吉彦、廣瀬友靖、砂塚敏明
- Organizer
  第65回天然有機化合物討論
- Data Source
  KAKENHI-PROJECT-21K05059
[Presentation] 大村天然物を基盤とした中分子創薬研究における合成展開2023
- Author(s)
  廣瀬友靖、岩月正人、砂塚敏明
- Organizer
  日本薬学会第143年会
- Invited
- Data Source
  KAKENHI-PROJECT-21K05059
[Presentation] 新規PPI阻害剤創製を指向した中分子天然物ジチロマイシンの全合成研究-12023
- Author(s)
  鈴木大貴、金井田將裕、野口吉彦、廣瀬友靖、砂塚敏明
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-21K05059
[Presentation] 新規PPI阻害剤創製を指向した中分子天然物ジチロマイシンの全合成研究 -2-2023
- Author(s)
  金井田將裕、野口吉彦、鈴木大貴、廣瀬友靖、砂塚敏明
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-21K05059
[Presentation] 新規PPI阻害剤創製を指向した中分子天然物ジチロマイシンの全合成研究-22023
- Author(s)
  金井田將裕、鈴木大貴、野口吉彦、廣瀬友靖、砂塚敏明
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-21K05059
[Presentation] In situ click chemistryを用いた新規メタロ-β-ラクタマーゼ阻害剤の探索研究2022
- Author(s)
  中里貴々、池田朱里、冨山昴大、池谷佳紀、本庄雅子、浅見行弘、廣瀬友靖、砂塚敏明
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-21K05059
[Presentation] チオエーテル疎水性アンカー分子を用いた抗マラリア活性リポペプチドKozupeptin Aの環化誘導体合成2022
- Author(s)
  上田あかり、廣瀬友靖、林裕美、穗苅玲、石山亜紀、岩月正人、砂塚敏明
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-21K05059
[Presentation] 創薬を志向した大村天然物の合成と新手法の開発2022
- Author(s)
  砂塚敏明
- Organizer
  日本薬学会第142年会
- Invited
- Data Source
  KAKENHI-PROJECT-21K05059
[Presentation] 新規PPI阻害剤創製を指向した中分子天然物ジチロマイシンの全合成研究2022
- Author(s)
  金井田將裕、野口吉彦、堤隼馬、稲橋佑起、廣瀬友靖、砂塚敏明
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-21K05059
[Presentation] コンビナトリアルライブラリー構築を指向したエバーメクチン類の全合成研究2022
- Author(s)
  齋藤亮、千成恒、佐藤翔悟、小川昌也、君嶋葵、増井悠、高橋孝志、廣瀬友靖、砂塚敏明
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-21K05059
[Presentation] 抗トリパノソーマ活性を有するActinoallolide Aの全合成研究2022
- Author(s)
  大野孝典、野口吉彦、渡邊彰人、岩月正人、稲橋佑起、廣瀬友靖、砂塚敏明
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-21K05059
[Presentation] 夢のある大村天然物創薬2021
- Author(s)
  砂塚敏明
- Organizer
  第36回創薬セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-21K05059
[Presentation] コンビナトリアルライブラリー構築を指向したエバーメクチン類の全合成研究2019
- Author(s)
  齋藤亮、君嶋葵、千成恒、佐藤翔悟、廣瀬友靖、増井悠、高橋孝志、大村智、砂塚敏明
- Organizer
  日本薬学会第139回年会
- Data Source
  KAKENHI-PUBLICLY-18H04629
[Presentation] 抗トリパノソーマを有するActinoallolide Aの全合成研究2019
- Author(s)
  渡邊彰人、野口吉彦、大西倫、廣瀬友靖、岩月正人、稲橋佑起、大村智、砂塚敏明
- Organizer
  日本薬学会第139回年会
- Data Source
  KAKENHI-PUBLICLY-18H04629
[Presentation] 疎水性タグを用いた環状デプシペプチド類の全合成2019
- Author(s)
  野口吉彦、野垣祐貴、廣瀬友靖、村島徳史、佐竹雄大、大村智、砂塚敏明
- Organizer
  日本薬学会第139回年会
- Data Source
  KAKENHI-PUBLICLY-18H04629
[Presentation] コンビナトリアルライブラリー構築を指向したエバーメクチン類の全合成研究2019
- Author(s)
  齋藤亮、君嶋葵、千成恒、佐藤翔悟、廣瀬友靖、増井悠、高橋孝志、大村智、砂塚敏明
- Organizer
  日本薬学会第139回年会
- Data Source
  KAKENHI-PROJECT-16K08174
[Presentation] 新規抗マラリア活性リポペプチドkozupeptin Aの実用的全合成、絶対立体構造の決定および抗マラリア活性の評価2019
- Author(s)
  林裕美、廣瀬友靖、深澤航、岩月正人、穂苅玲、石山亜紀、野中健一、塩見和朗、大村智、砂塚敏明
- Organizer
  第115回有機合成シンポジウム
- Data Source
  KAKENHI-PUBLICLY-18H04629
[Presentation] 疎水性タグを用いた環状デプシペプチド類の全合成2019
- Author(s)
  野口吉彦、野垣祐貴、廣瀬友靖、村島徳史、佐竹雄大、大村智、砂塚敏明
- Organizer
  日本薬学会第139回年会
- Data Source
  KAKENHI-PROJECT-16K08174
[Presentation] 抗嫌気性菌活性を有するルミナミシンの全合成研究；10員環ラクトンの構築2019
- Author(s)
  安藤博康、大原基義、君嶋葵、廣瀬友靖、金井田將裕、宮本岳洋、大村智、砂塚敏明
- Organizer
  日本薬学会第139回年会
- Data Source
  KAKENHI-PUBLICLY-18H04629
[Presentation] 薬剤感受性出芽酵母を用いた微生物二次代謝産物からの抗真菌薬シード化合物の探索2018
- Author(s)
  坂井克行、廣瀬友靖、岩月正人、知念拓実、木村徹、須賀拓弥、野中健一、中島琢自、砂塚敏明、臼井健郎，浅見行弘、大村智、塩見和朗
- Organizer
  第101回日本細菌学会関東支部総会
- Data Source
  KAKENHI-PUBLICLY-18H04629
[Presentation] 疎水性タグを用いた環状デプシペプチド類の全合成2018
- Author(s)
  野口吉彦、野垣祐貴、廣瀬友靖、村島徳史、佐竹雄大、大村智、砂塚敏明
- Organizer
  日本薬学会第139回年会
- Data Source
  KAKENHI-PUBLICLY-18H04629
[Presentation] 日本発の大村天然物による微生物創薬2018
- Author(s)
  砂塚　敏明
- Organizer
  平成30年度後期有機合成化学講習会
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04629
[Presentation] コンビナトリアルライブラリー構築を指向したエバーメクチン類の全合成研究2018
- Author(s)
  齋藤亮、君嶋葵、千成恒、佐藤翔悟、廣瀬友靖、増井悠、高橋孝志、大村智、砂塚敏明
- Organizer
  日本薬学会第139回年会
- Data Source
  KAKENHI-PUBLICLY-18H04629
[Presentation] 大村創薬グループにおける微生物創薬2018
- Author(s)
  砂塚　敏明
- Organizer
  第36回メディシナルケミストリーシンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-16K08174
[Presentation] 大村創薬グループにおける微生物創薬2018
- Author(s)
  砂塚　敏明
- Organizer
  第36回メディシナルケミストリーシンポジウム
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04629
[Presentation] 日本発の大村天然物による微生物創薬2018
- Author(s)
  砂塚　敏明
- Organizer
  平成30年度後期有機合成化学講習会
- Invited
- Data Source
  KAKENHI-PROJECT-16K08174
[Presentation] 薬剤感受性出芽酵母を用いた微生物二次代謝産物からの抗真菌薬シード化合物の探索2018
- Author(s)
  坂井克行，廣瀬友靖，岩月正人、知念拓実、木村徹、須賀拓弥，野中健一、中島琢自、砂塚敏明、臼井健郎，浅見行弘、大村智、塩見和朗
- Organizer
  第101回日本細菌学会関東支部総会
- Data Source
  KAKENHI-PROJECT-16K08174
[Presentation] 大村天然物の可能性を引き出す創薬研究2017
- Author(s)
  砂塚敏明
- Organizer
  第22回日本病態プロテアーゼ学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-16K08174
[Presentation] 抗トリパノソーマ活性を有するマングロマイシン類の単離、構造決定ならびに不斉全合成2017
- Author(s)
  廣瀬友靖、中島琢自、高田拓和、岩月正人、山田健、落合純也、神谷義之、石原拓真、長井賢一郎、松本厚子、石山亜紀、乙黒一彦、塩見和朗、高橋洋子、砂塚敏明、大村智
- Organizer
  第59回天然有機化合物討論会
- Data Source
  KAKENHI-PROJECT-16K08174
[Presentation] 北里微生物資源ライブラリーを基盤とした多剤耐性菌を克服する天然物創薬2017
- Author(s)
  砂塚敏明
- Organizer
  薬剤耐性(AMR)シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-16K08174
[Presentation] 抗トリパノソーマ活性を有するMangromicin Aの全合成と絶対立体構造の決定2017
- Author(s)
  高田拓和、山田健、廣瀬友靖、石原拓真、中島琢自、高橋洋子、大村智、砂塚敏明
- Organizer
  日本薬学会第137年会
- Place of Presentation
  東北大学、宮城県仙台市
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-16K08174
[Presentation] 抗マラリア活性を有するPuberulic acid類の全合成と構造活性相関研究2017
- Author(s)
  齋藤亮、千成恒、廣瀬友靖、岩月正人、石山亜紀、穂苅玲、乙黒一彦、大村智、砂塚敏明
- Organizer
  第35回メディシナルケミストリーシンポジウム
- Data Source
  KAKENHI-PROJECT-16K08174
[Presentation] 微生物由来天然物をリード化合物とする創薬の方向性2017
- Author(s)
  砂塚敏明
- Organizer
  第91回日本感染症学会総会学術講演会、第65回日本化学療法学術集会　合同学会
- Invited
- Data Source
  KAKENHI-PROJECT-16K08174
[Presentation] 北里発の微生物由来天然物の合成と創薬展開2016
- Author(s)
  砂塚敏明
- Organizer
  第33回有機合成化学セミナー
- Place of Presentation
  ヒルトンニセコビレッジ、北海道虻田郡
- Year and Date
  2016-09-06
- Invited
- Data Source
  KAKENHI-PROJECT-16K08174
[Presentation] Synthetic Strategy for Construction of Unique Polycyclic Natural Products2016
- Author(s)
  Toshiaki Sunazuka
- Organizer
  Natural Products & Bioactive Compounds Gordon Research Conference
- Place of Presentation
  Proctor Academy Andover, NH, US.
- Year and Date
  2016-07-31
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08174
[Presentation] In the Harmony between Natural Products and Organic Synthesis2016
- Author(s)
  Toshiaki Sunazuka
- Organizer
  25th French-Japanese Symposium on Medicinal and Fine Chemistry (FJS 2016)
- Place of Presentation
  Keio Plaza Hotel Tama, Japan
- Year and Date
  2016-05-15
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08174
[Presentation] Microbial Natural Products as Splendid Gifts for Drug Discovery for Human, Animal and Agriculture2016
- Author(s)
  Toshiaki Sunazuka
- Organizer
  The 71th Annual Academic Congress of Korean Association of Biological Sciences
- Place of Presentation
  Samyuk University, Korea
- Year and Date
  2016-08-10
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08174
[Presentation] Total Synthesis of Unique Polycyclic Bioactive Natural Products- Failure Leads to Success -2015
- Author(s)
  Toshiaki Sunazuka
- Organizer
  Symposium in Honor of Professor Amos B. Smith, III; The Recipient of the 2015 Allan R. Day Award
- Place of Presentation
  Philadelphia, USA
- Year and Date
  2015-10-17
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460020
[Presentation] 特異な多環式含窒素生物活性天然物の分子骨格構築法の開発と全合成2015
- Author(s)
  砂塚敏明
- Organizer
  第70回記念有機合成化学協会関東支部シンポジウム
- Place of Presentation
  長岡工業高等専門学校（新潟県長岡市）
- Year and Date
  2015-11-21
- Invited
- Data Source
  KAKENHI-PLANNED-23105012
[Presentation] 天然有機化合物の魅力を引き出す有機合成化学の醍醐味2015
- Author(s)
  砂塚敏明
- Organizer
  日本化学会関東支部群馬地区講演会
- Place of Presentation
  群馬大学（群馬県桐生市）
- Year and Date
  2015-07-07
- Invited
- Data Source
  KAKENHI-PROJECT-25460020
[Presentation] Isolation and total synthesis of microbial natural products2015
- Author(s)
  Toshiaki Sunazuka; Tomoyasu Hirose and Satoshi Omura
- Organizer
  Pacifichem 2015
- Place of Presentation
  Hawaii, USA
- Year and Date
  2015-12-15
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-23105012
[Presentation] Total synthesis of unique polycyclic bioactive indole alkaloids2015
- Author(s)
  Toshiaki Sunazuka
- Organizer
  16th Tetrahedron Symposium, Grand Hyatt Berlin, Germany
- Place of Presentation
  Berlin, Germany
- Year and Date
  2015-06-16
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460020
[Presentation] Total Synthesis of Novel Polycyclic Biological Active Indole Alkaloids2015
- Author(s)
  Toshiaki Sunazuka
- Organizer
  The 6th Japanese-Sino Symposium on Organic Chemistr
- Place of Presentation
  Akiu Resort Hotel Crescent, Sendai
- Year and Date
  2015-09-07
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460020
[Presentation] Drug discovery based on microbial bioactive natural products2015
- Author(s)
  Toshiaki Sunazuka and Satoshi Omura
- Organizer
  Pacifichem 2015
- Place of Presentation
  Hawaii, USA
- Year and Date
  2015-12-15
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-23105012
[Presentation] 有機分子触媒を用いたイソシアニドとアルデヒドのα-付加反応2015
- Author(s)
  山田健, 廣瀬友靖, 大村智, 砂塚敏明
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸学院大学（神戸）
- Year and Date
  2015-03-27
- Data Source
  KAKENHI-PLANNED-23105012
[Presentation] Total Synthesis of Unique Polycyclic Bioactive Natural Products- Failure Leads to Success -2015
- Author(s)
  Toshiaki Sunazuka
- Organizer
  Symposium in Honor of Professor Amos B. Smith, III; The Recipient of the 2015 Allan R. Day Award
- Place of Presentation
  Philadelphia, USA
- Year and Date
  2015-11-17
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-23105012
[Presentation] Total synthesis of unique polycyclic bioactive indole alkaloids2015
- Author(s)
  Toshiaki Sunazuka
- Organizer
  16th Tetrahedron Symposium
- Place of Presentation
  Berlin. Germany
- Year and Date
  2015-06-15
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-23105012
[Presentation] Drug discovery based on microbial bioactive natural products2015
- Author(s)
  Toshiaki Sunazuka, and Satoshi Omura
- Organizer
  Pacifichem 2015
- Place of Presentation
  Hawaii, USA
- Year and Date
  2015-12-15
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460020
[Presentation] 有機分子触媒を用いたイソシアニドとアルデヒドのα-付加反応2014
- Author(s)
  山田健, 廣瀬友靖, 大村智, 砂塚敏明
- Organizer
  「有機分子触媒による未来型分子変換」第４回公開シンポジウム（分子活性化-有機分子触媒合同シンポジウム）
- Place of Presentation
  北海道大学（札幌）
- Year and Date
  2014-06-20
- Data Source
  KAKENHI-PLANNED-23105012
[Presentation] マクロライド骨格をテンプレートとした新規キチナーゼ阻害剤の創製2013
- Author(s)
  菅原章公、真板宣夫、廣瀬友靖、木村紗穂莉、斉藤佳史、山本剛、渡邉剛志、塩見和朗、中野洋文、谷口寿章、大村智、砂塚敏明
- Organizer
  日本薬学会第１３３年会
- Place of Presentation
  横浜
- Year and Date
  2013-03-27
- Data Source
  KAKENHI-PLANNED-23105012
[Presentation] マクロライド骨格をテンプレートとした新規キチナーゼ阻害剤の創製2013
- Author(s)
  菅原章公、真板宣夫、廣瀬友靖、木村紗穂莉、斉藤佳史、井上浄、山本剛、渡邉剛志、塩見和朗、中野洋文、谷口寿章、大村智、砂塚敏明
- Organizer
  日本ケミカルバイオロジー学会第８回年会
- Place of Presentation
  東京都
- Data Source
  KAKENHI-PROJECT-25460020
[Presentation] Practical Synthesis of Bioactive Natural products by Organocatalysts2013
- Author(s)
  Toshiaki Sunazuka
- Organizer
  新学術領域（有機触媒）第４回公開シンポジウム
- Place of Presentation
  滋賀県
- Invited
- Data Source
  KAKENHI-PROJECT-25460020
[Presentation] マクロライド骨格をテンプレートとした新規キチナーゼ阻害剤の創製2013
- Author(s)
  菅原章公、廣瀬友靖、大村智、砂塚敏明
- Organizer
  新学術領域第４回公開シンポジウム
- Place of Presentation
  茨城県
- Data Source
  KAKENHI-PROJECT-25460020
[Presentation] Total Synthesis of Novel Polycyclic Bioactive Natural Products2013
- Author(s)
  Toshiaki Sunazuka
- Organizer
  Gordon Conference on Heterocyclic Compounds
- Place of Presentation
  アメリカ、ボストン
- Invited
- Data Source
  KAKENHI-PLANNED-23105012
[Presentation] マクロライド骨格をテンプレートとした新規キチナーゼ阻害剤の創製2013
- Author(s)
  菅原章公、廣瀬友靖、大村智、砂塚敏明
- Organizer
  新学術領域第４回公開シンポジウム
- Place of Presentation
  茨城県
- Data Source
  KAKENHI-PLANNED-23105012
[Presentation] マクロライド骨格をテンプレートとした新規キチナーゼ阻害剤の創製2013
- Author(s)
  菅原章公、真板宣夫、廣瀬友靖、合田浩明、木村紗穂莉、斉藤佳史、井上浄、山本剛、渡邉剛志、塩見和朗、中野洋文、広野修一、谷口寿章、大村智、砂塚敏明
- Organizer
  第５５回天然有機化合物討論会
- Place of Presentation
  京都府
- Data Source
  KAKENHI-PLANNED-23105012
[Presentation] Luminamicinの全合成研究(2)；11-oxatricyclo[5.3.1.0]undecane骨格の構築2013
- Author(s)
  君嶋葵、菅原章公、廣瀬友靖、高田拓和、松丸尊紀、戸田正輝、大村智、砂塚敏明
- Organizer
  日本薬学会第１３３年会
- Place of Presentation
  横浜
- Year and Date
  2013-03-27
- Data Source
  KAKENHI-PLANNED-23105012
[Presentation] Practical Synthesis of Bioactive Natural products by Organocatalysts2013
- Author(s)
  Toshiaki Sunazuka
- Organizer
  新学術領域第４回公開国際シンポジウム
- Place of Presentation
  滋賀県
- Invited
- Data Source
  KAKENHI-PLANNED-23105012
[Presentation] Total Synthesis of Novel Polycyclic Bioactive Natural Products2013
- Author(s)
  Toshiaki Sunazuka
- Organizer
  Total Synthesis of Novel Polycyclic Bioactive Natural Products
- Place of Presentation
  アメリカ、ボストン
- Invited
- Data Source
  KAKENHI-PROJECT-25460020
[Presentation] マクロライド骨格をテンプレートとした新規キチナーゼ阻害剤の創製2013
- Author(s)
  菅原章公、真板宣夫、廣瀬友靖、木村紗穂莉、斉藤佳史、井上浄、山本剛、渡邉剛志、塩見和朗、中野洋文、谷口寿章、大村智、砂塚敏明
- Organizer
  日本ケミカルバイオロジー学会第８回年会
- Place of Presentation
  東京都
- Data Source
  KAKENHI-PLANNED-23105012
[Presentation] マクロライド骨格をテンプレートとした新規キチナーゼ阻害剤の創製2013
- Author(s)
  菅原章公、真板宣夫、廣瀬友靖、合田浩明、木村紗穂莉、斉藤佳史、井上浄、山本剛、渡邉剛志、塩見和朗、中野洋文、広野修一、谷口寿章、大村智、砂塚敏明
- Organizer
  第５５回天然有機化合物討論会
- Place of Presentation
  京都府
- Data Source
  KAKENHI-PROJECT-25460020
[Presentation] Luminamicinの全合成研究 (1)；共役無水マレイン酸含有14員環マクロライドの合成法の確立2013
- Author(s)
  高田拓和、菅原章公、廣瀬友靖、君嶋葵、松丸尊紀、戸田正輝、大村智、砂塚敏明
- Organizer
  日本薬学会第１３３年会
- Place of Presentation
  横浜
- Year and Date
  2013-03-27
- Data Source
  KAKENHI-PLANNED-23105012
[Presentation] 有機触媒を用いた創薬を指向した生理活性天然物の実践的合成2012
- Author(s)
  砂塚敏明
- Organizer
  文部科学省科学研究費補助金「新学術領域研究（研究領域提案型）」第１回全体会議
- Place of Presentation
  京都
- Year and Date
  2012-06-08
- Data Source
  KAKENHI-PLANNED-23105012
[Presentation] Total synthesis of novel polycyclic bioactive indole alkaloids2012
- Author(s)
  Toshiaki Sunazuka
- Organizer
  12^<th> ICCA
- Place of Presentation
  ベルリン(ドイツ)(招待講演)
- Year and Date
  2012-09-12
- Data Source
  KAKENHI-PLANNED-23105012
[Presentation] Total synthesis of novel polycyclic bioactive indole alkaloids2012
- Author(s)
  Toshiaki Sunazuka
- Organizer
  14th Asian Chemical Congress 2011 (14 ACC)
- Place of Presentation
  バンコク(タイ)(招待講演)
- Year and Date
  2012-09-06
- Data Source
  KAKENHI-PLANNED-23105012
[Presentation] Total synthesis of novel polycyclic bioactive indole alkaloids2011
- Author(s)
  Toshiaki Sunazuka
- Organizer
  12^<th> ICCA
- Place of Presentation
  ベルリン(ドイツ)(招待講演)
- Year and Date
  2011-09-12
- Data Source
  KAKENHI-PROJECT-21590020
[Presentation] Total synthesis of novel polycyclic bioactive indole alkaloid2011
- Author(s)
  Sunazuka, T
- Organizer
  12th International Conference on the Chemistry of Antibiotics and other Bioactive
- Place of Presentation
  Berlin(Germany)
- Data Source
  KAKENHI-PROJECT-21590020
[Presentation] Total synthesis of novel polycyclic bioactive indole alkaloids2011
- Author(s)
  Sunazuka, T
- Organizer
  14th Asian Chemical Congress 2011(14 ACC)
- Place of Presentation
  Bangkok(Thailand)
- Data Source
  KAKENHI-PROJECT-21590020
[Presentation] Total Synthesis of Novel Polycyclic Bioactive Indole Alkaloids2010
- Author(s)
  Sunazuka, T
- Organizer
  The 5th International Conference on Cutting-Edge Organic Chemistry
- Place of Presentation
  Asia(China)
- Data Source
  KAKENHI-PROJECT-21590020
[Presentation] Total Synthesis of Novel Polycyclic Bioactive Indole Alkaloids2010
- Author(s)
  Toshiaki Sunazuka
- Organizer
  The 5^<th> International Conference on Cutting-Edge Organic Chemistry in Asia
- Place of Presentation
  台湾
- Year and Date
  2010-11-09
- Data Source
  KAKENHI-PROJECT-21590020
[Presentation] 複雑な含窒素多環式天然物の合成研究2010
- Author(s)
  砂塚敏明
- Organizer
  日本薬学会130年会
- Place of Presentation
  岡山
- Year and Date
  2010-03-30
- Data Source
  KAKENHI-PROJECT-21590020
[Presentation] Effect of a Kampo medicine “Shoseiryuto" on airway inflammation and adjuvant activity for influenza vaccine.2007
- Author(s)
  Y. Shimizu, T. Nagai, H. Kiyohara, T. Shirahata, T. Sunazuka, S. Omura, H. Yamada
- Organizer
  The 24th General Meeting of Medical and Pharmaceutical Society for WAKAN-YAKU
- Place of Presentation
  Toyama (Japan)
- Year and Date
  2007-09-08
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590601
[Presentation] 多環式含窒素生体機能分子の実践的合成2007
- Author(s)
  砂塚敏明
- Organizer
  生体機能分子の創製第5回公開シンポジウム
- Place of Presentation
  大阪、千里
- Year and Date
  2007-12-14
- Data Source
  KAKENHI-PROJECT-18032066
[Presentation] Combination effect of pinellic acid stereoisomers on adjuvant activity against nasal influenza vaccine.2007
- Author(s)
  T. Nagai, Y. Shimizu, H. Kiyohara, T. Shirahata, T. Sunazuka, S. Omura, H. Yamada
- Organizer
  The 127th Annual Meeting of the Pharmaceutical Society of Japan
- Place of Presentation
  Toyama (Japan)
- Year and Date
  2007-03-30
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590601
[Presentation] 小青竜湯の気道炎症に対する作用及びインフルエンザワクチンに対するアジュバント活性の検討2007
- Author(s)
  清水ユリ子、永井隆之、清原寛章、白畑辰弥、砂塚敏明、他2名
- Organizer
  第24回和漢医薬学会大会
- Place of Presentation
  富山市(富山国際会議場)
- Year and Date
  2007-09-08
- Data Source
  KAKENHI-PROJECT-17590601
[Presentation] Solid Phase Total Synthesis of a Novel Chitinase Inhibitor,Argifin2007
- Author(s)
  砂塚敏明
- Organizer
  第10回国際抗生物質化学会議
- Place of Presentation
  アメリカ、ナッシュビル
- Year and Date
  2007-08-12
- Data Source
  KAKENHI-PROJECT-18590015
[Presentation] Pharmacological effects of Kampo (Japanese herbal) medicines through airway mucosal immune system.2006
- Author(s)
  H. Yamada, T. Nagai, H. Kiyohara, M. Nakao, T. Sunazuka, S. Omura
- Organizer
  20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress
- Place of Presentation
  Kyoto (Japan)
- Year and Date
  2006-06-23
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590601
[Presentation] 天然有機化合物を基盤とした新しい創薬研究
- Author(s)
  砂塚敏明
- Organizer
  第29回農薬デザイン研究会
- Place of Presentation
  ホテルニューアカオ（熱海）
- Year and Date
  2014-11-06 – 2014-11-07
- Invited
- Data Source
  KAKENHI-PROJECT-25460020
[Presentation] Practical synthesis of bioactive natural products using organocatalysts
- Author(s)
  Toshiaki Sunazuka
- Organizer
  第2回国際会議(兼)第7回有機触媒シンポジウム
- Place of Presentation
  東大（東京）
- Year and Date
  2014-11-21 – 2014-11-22
- Invited
- Data Source
  KAKENHI-PROJECT-25460020
[Presentation] Concise Asymmetric Total Synthesis of Neoxaline Family
- Author(s)
  Tetsuya Ideguchi, Takeshi Yamada, Tatsuya Shirahata, Tomoyasu Hirose, Akihiro Sugawara, Yoshinori Kobayashi, Satoshi Ōmura, Toshiaki Sunazuka
- Organizer
  Advanced Molecular Transformation by Organocatalysts 2nd International Conference & 7th Symposium on Organocatalysis
- Place of Presentation
  Tokyo University (Tokyo)
- Year and Date
  2014-11-21 – 2014-11-22
- Data Source
  KAKENHI-PLANNED-23105012
[Presentation] Practical synthesis of bioactive natural products using organocatalysts
- Author(s)
  Toshiaki Sunazuka
- Organizer
  Advanced Molecular Transformation by Organocatalysts 2nd International Conference & 7th Symposium on Organocatalysis
- Place of Presentation
  Tokyo University (Tokyo)
- Year and Date
  2014-11-21 – 2014-11-22
- Invited
- Data Source
  KAKENHI-PLANNED-23105012
[Presentation] Harmonization between natural products and organic synthesis for drug discovery
- Author(s)
  Toshiaki Sunazuka
- Organizer
  International Conference on Advances in Engineering, Technology and science 2014
- Place of Presentation
  China, Beijing
- Year and Date
  2014-06-02 – 2014-06-03
- Invited
- Data Source
  KAKENHI-PROJECT-25460020
[Presentation] Chemoselective Functionalization of Bioactive Polyol Natural Products using Organocatalyst
- Author(s)
  Takeshi Yamada, Tomoyasu Hirose, Koh Suzuki, Misato Hosaka, Takumi Furuta, Takeo Kawabata, Satoshi Ōmura, Toshiaki Sunazuka
- Organizer
  Advanced Molecular Transformation by Organocatalysts 2nd International Conference & 7th Symposium on Organocatalysis
- Place of Presentation
  Tokyo University (Tokyo)
- Year and Date
  2014-11-21 – 2014-11-23
- Data Source
  KAKENHI-PLANNED-23105012

1. OMURA Satoshi (90050426)

# of Collaborated Projects: 6 results

# of Collaborated Products: 6 results
2. TOMODA Hiroshi (70164043)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
3. ISHIBASHI Shun (90212919)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. INOKOSHI Junji (30151640)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. NAGAMITSU Tohru (90300756)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. MATSUNE Shoji (00253899)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. KURONO Yuichi (80153427)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. OHKUBO Kimihiro (10213654)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. ADUMA Arata (10184194)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. FUJIKURA Terumichi (00238552)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. GOTO Yuduru (80281426)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. OBATA Rika (20260078)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. TABATA Noriko (60260080)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. NAGAI Takayuji (00172487)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
15. KIYOHARA Hiroaki (70161601)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
16. Nagai Ryozo (60207975)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. Maekawa Tomoki (50625168)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 吉福孝介 (70381168)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 大堀純一郎 (90507162)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 横山茂之 (00159229)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 相澤健一 (70436484)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 土門久哲 (00594350)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 寺尾豊 (50397717)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. IWATSUKI Masato

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. YAMADA Takeshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
26. SUGAWARA Akihiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
27. 廣瀬友靖

# of Collaborated Projects: 0 results

# of Collaborated Products: 10 results
28. 真板宣夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. 谷口寿章

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Sunazuka Toshiaki 砂塚 敏明

SUNAZUKA Toshiaki 砂塚 敏明

Research Projects

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Synthesis of the lead compound of PPI inhibitor, DityromycinPrincipal Investigator

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Therapeutic strategies against inflammation and bone loss associated with Del-1 production

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Development of a novel PDK4 inhibitor as a new therapeutic agent for heart failure

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Creation of chemical tools and pharmaceuticals leads using Omura natural productsPrincipal Investigator

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Cascade and efficient total synthesisor for drug discovery of tropical diseasePrincipal Investigator

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Synthetic Strategy for Construction of Unique Polycyclic Indole Alkaloids by cascade reactionsPrincipal Investigator

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Practical Synthesis of Bioactive Natural Products by OrganocatalystsPrincipal Investigator

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New therapy for refractory chronic sinusitis in application with priming effect of macrolide on steroid therapy

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Total synthesis of novel polycyclic bioactive indole alkaloidsPrincipal Investigator

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ガン調節機能を有する多環式含窒素生体機能分子の実践的合成Principal Investigator

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Discovery and development of selectivity-defined inhibitors toward two acyl-CoA : cholesterol acyltransferase isozymes

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合理的ドラックデザインを駆使した抗感染症薬の創製とマクロライドへの骨格変換Principal Investigator

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ガン調節機能を有する多環式含窒素生体機能分子の実践的合成Principal Investigator

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Sunazuka Toshiaki 砂塚敏明

SUNAZUKA Toshiaki 砂塚敏明