Chikuda Hirotaka 筑田博隆

… Alternative Names

CHIKUDA Hirotaka 筑田博隆

筑田博隆チクダヒロタカ

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Researcher Number	30345219
Other IDs	https://orcid.org/0000-0002-7913-1542
Affiliation (Current)	2024: 群馬大学, 大学院医学系研究科, 教授
Affiliation (based on the past Project Information) *help	2016 – 2024: 群馬大学, 大学院医学系研究科, 教授 2016: 東京大学, 医学部附属病院, 講師(移行) 2014 – 2016: 東京大学, 医学部附属病院, 准教授 2012 – 2014: 東京大学, 医学部附属病院, 講師 2012: 東京大学, 大学院・医学系研究科, 講師 … More 2011: 東京大学, 医学部附属病院, 特任講師 2008 – 2011: The University of Tokyo, 医学部附属病院, 助教 2004: 東大, 医学部附属病院 2003: 東京大学, 医学部附属病院, 助手 Less
Review Section/Research Field	Principal Investigator Orthopaedic surgery / Basic Section 56020:Orthopedics-related Except Principal Investigator Orthopaedic surgery / Basic Section 56020:Orthopedics-related / Surgical dentistry / Basic Section 59010:Rehabilitation science-related / Basic Section 57060:Surgical dentistry-related / Oral Science and related fields / Biomedical engineering/Biomaterial science and engineering
Keywords	Principal Investigator 変形性関節症 / 脊椎脊髄病学 / 関節軟骨 / 血圧管理 / 脊髄損傷 / ヒトRANKLモノクローナル抗体 / 原発性骨腫瘍 / デノスマブ / 骨巨細胞種 / RANKL … More / 光免疫療法 / 骨巨細胞腫 / 整形外科学 / 脊椎 / プロテオーム / 脊椎脊髄疾患 / バイオマーカー / 有尾両生類 / 再生医療 / メカニカルストレス / 軟骨細胞肥大分化 / 軟骨代謝学 / 骨 / Notchシグナル / 関節炎 / 骨代謝 / Runx2 / GSK3β / Sox9 / 軟骨分化 / 成長板 / cGKII … More Except Principal Investigator 細胞周期 / 再生医学 / 変形性関節症 / 整形外科学 / 細胞分化 / 骨代謝学 / 骨代謝 / 発生・分化 / 骨軟骨代謝学 / シグナル伝達 / 幹細胞 / 骨再生 / 骨 / パソコン・スマートフォン / デスクワーカー / 前腕伸筋・腱 / 超音波エラストグラフィー / テニス肘 / リピドミクス解析 / 痛み・しびれ / 脳脊髄同時計測機能的MRI / 予測的姿勢制御 / 固有位置覚 / 運動制御 / 中枢神経 / 肩腱板断裂 / 組織修復 / 体外衝撃波 / 軟骨系細胞 / ESWT / 腱板断裂 / バイオマーカー / メタボローム / 変形性股関節症 / メタボロミクス / メタボローム解析 / 急速破壊型股関節症 / 再生医療 / G0/G1期 / 骨格幹細胞 / microRNA / micro RNA / エクソソーム / 脊椎 / 運動器 / 医療・福祉 / Wntシグナル / メカニカルストレス / 骨化 / 後縦靭帯 / 靱帯 / Rspo2 / GWAS / 後縦靭帯骨化症 / OPLL / Wnt経路 / RSPO2 / 頚椎後縦靭帯骨化症 / 難治神経疾患 / DDS / mRNA医薬 / 脊髄損傷 / 神経疾患 / 送達システム / mRNA / regenerative medicine / culture methods / optimal differentiation condition / chondrocyte differentiation / osteoblast differentiation / embryonic stem (ES) cells / 胚性幹細胞(ES) / 分化誘導 / 胚性幹細胞 / 再生 / 軟骨 / 培養方法 / 分化十分条件 / 軟骨分化 / 骨分化 / 胚性幹(ES)細胞 / 骨軟骨分化 / 骨吸収 / 骨形成 / 外科学 / 関節病学 / NF-kBシグナル / 軟骨細胞 / Notchシグナル / Adam17 / Camk2 / Hes1 / 関節軟骨 / ノックアウトマウス / クロマチン免疫沈降法 / 骨系統疾患 / 遺伝子操作マウス / EBPファミリー / C / 軟骨代謝 / Runx2 / C/EBPファミリー / 軟骨代謝学 / 骨・軟骨代謝 / 骨粗鬆症 / 副甲状腺ホルモン / 骨軟骨代謝 / 細胞・組織 / NFκB / NF-kB / 骨・軟骨代謝学 Less

高齢頚髄損傷の治療成績改善にむけた非侵襲血圧維持療法BP augmentationの開発Principal Investigator
- Principal Investigator
  
  筑田博隆
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Gunma University
Establishing an Objective Evaluation Platform for Pain and Numbness Severity Using Combination of Cerebrospinal Fluid Lipidomics Biomarkers and Simultaneous Brain-Spinal Cord fMRI
- Principal Investigator
  
  高澤英嗣
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Gunma University
Can the elasticity of the muscles and tendons of the forearm extensor be a predictor of the development of tennis elbow?
- Principal Investigator
  
  田鹿毅
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59010:Rehabilitation science-related
- Research Institution
  Gunma University
腱板断裂修復部に対する体外衝撃波の組織修復促進効果の検討
- Principal Investigator
  
  一ノ瀬剛
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Gunma University
Motor control on the central nervous system in patients with rotator cuff tear
- Principal Investigator
  
  設楽仁
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Gunma University
骨巨細胞腫に対するヒトRANKLモノクローナル抗体による光免疫療法の開発Principal Investigator
- Principal Investigator
  
  筑田博隆
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Gunma University
メタボローム解析を用いた急速破壊型股関節症におけるバイオマーカーの検索
- Principal Investigator
  
  高嶺周平
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Gunma University
Cdk6による骨格幹細胞G0/G1期制御機構の解明と骨再生医療に向けた基礎的検討
- Principal Investigator
  
  小笠原徹
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  The University of Tokyo
Identification of novel osteoclast-osteoblast coupling factors in exosomes involving cell cycle machinery
- Principal Investigator
  
  Ogasawara Toru
- Project Period (FY)
  2017 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  Oral Science and related fields
- Research Institution
  The University of Tokyo
Comprehensive research for molecular regulation of development, homeostasis, and degeneration of spinePrincipal Investigator
- Principal Investigator
  
  Chikuda Hirotaka
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Gunma University
Function of RSPO2 in progerssion of OPLL
- Principal Investigator
  
  Matsubayashi Yoshitaka
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  The University of Tokyo
Basic research for a long-life spinal implant providing dynamic stability and anti-infective property
- Principal Investigator
  
  Oshima Yasushi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  The University of Tokyo
Cerebrospinal Fluid Biomarkers for Lumbar Spinal Stenosis Identified by an Exhaustive search with High-Resolution Mass SpectrometryPrincipal Investigator
- Principal Investigator
  
  Chikuda Hirotaka
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Gunma University
Identification of microRNAs controlled by Cdk6 for understanding of bone metabolism system and their application for regenerative medicine
- Principal Investigator
  
  OGASAWARA Toru
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  The University of Tokyo
Development of mRNA medicine for treatment of neural diseases and injury
- Principal Investigator
  
  ITAKA Keiji
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  Tokyo Medical and Dental University
  The University of Tokyo
Analysis of the high ability of urodele amphibians to regenerate articular cartilage and application of the underlying mechanism to regeneration of mammalian cartilagePrincipal Investigator
- Principal Investigator
  
  Chikuda Hirotaka
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Orthopaedic surgery
- Research Institution
  The University of Tokyo
Strategic research of osteoarthritis for novel therapeutics
- Principal Investigator
  
  Kawaguchi Hiroshi
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  The University of Tokyo
Investigation of factors which simultaneously regulate bone formation and bone resorption in terms of cell cycle regulation.
- Principal Investigator
  
  OGASAWARA TORU
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Surgical dentistry
- Research Institution
  The University of Tokyo
Elucidation of the mechanism of bone metabolism controlled by Cdk6 transcription factory
- Principal Investigator
  
  OGASAWARA Toru
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  The University of Tokyo
Analyses of Notch signaling pathway in osteoarthritis
- Principal Investigator
  
  TAKETOMI Shuji
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  The University of Tokyo
Analyses of IKK signaling pathway in locomotive diseases
- Principal Investigator
  
  MATSUBARA Takehiro
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  The University of Tokyo
Research of Notch signal in pathophysiology and therapeutics of osteoarthritisPrincipal Investigator
- Principal Investigator
  
  CHIKUDA Hirotaka
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  The University of Tokyo
Establishment and application of in-vitro hypertrophic and degeneration model designed to clarify the mechanism of mechanical signal transduction in chondrocytes.Principal Investigator
- Principal Investigator
  
  CHIKUDA Hirotaka
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Orthopaedic surgery
- Research Institution
  The University of Tokyo
Novel therapeutic approaches to bone diseases using cell cycle factors Cdk4/6
- Principal Investigator
  
  OGASAWARA Toru
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Surgical dentistry
- Research Institution
  The University of Tokyo
Research of bone and cartilage regulation by NF-kB signal for innovative targeted therapy.
- Principal Investigator
  
  ITO Hideya
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  The University of Tokyo
β-catenin regulates parathyroid hormone/parathyroid hormone-related protein receptor signals and chondrocyte hypertrophy through binding to the intracellular C-terminal region of the receptor.
- Principal Investigator
  
  OGATA Naoshi
- Project Period (FY)
  2009 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  The University of Tokyo
Regulation of chondrocyte metabolism by transcription factor C/EBP families
- Principal Investigator
  
  MIURA Toshiki
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  The University of Tokyo
Molecular mechanisms of regulation in bone and cartilage metabolism by GSK3βPrincipal Investigator
- Principal Investigator
  
  CHIKUDA Hirotaka
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  The University of Tokyo
新規軟骨分化制御因子cGK2シグナルの骨再正における機能解析とその標的分子の同定Principal Investigator
- Principal Investigator
  
  筑田博隆
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  The University of Tokyo
Strategic study on osteoblast and chondrocyte differentiation from embryonic stem (ES) cells
- Principal Investigator
  
  CHUNG Ung-il
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  The University of Tokyo

All 2020 2019 2018 2017 2014 2013 2012 2011 2010 2009 2008 2005 2004

All Journal Article Presentation

[Journal Article] A systematic review and meta-analysis comparing anterior decompression with fusion and posterior laminoplasty for cervical ossification of the posterior longitudinal ligament2020
- Author(s)
  Yoshii Toshitaka、Egawa Satoru、Hirai Takashi、Kaito Takashi、Mori Kanji、Koda Masao、Chikuda Hirotaka、Hasegawa Tomohiko、Imagama Shiro、Yoshida Masahiro、Iwasaki Motoki、Okawa Atsushi、Kawaguchi Yoshiharu
- Journal Title
  
  Journal of Orthopaedic Science
  
  Volume: 25 Issue: 1 Pages: 58-65
- DOI
  10.1016/j.jos.2019.03.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04311, KAKENHI-PROJECT-19K09545
[Journal Article] Lysophosphatidic acids and their substrate lysophospholipids in cerebrospinal fluid as objective biomarkers for evaluating the severity of lumbar spinal stenosis2019
- Author(s)
  Hayakawa Kentaro、Kurano Makoto、Ohya Junichi、Oichi Takeshi、Kano Kuniyuki、Nishikawa Masako、Uranbileg Baasanjav、Kuwajima Ken、Sumitani Masahiko、Tanaka Sakae、Aoki Junken、Yatomi Yutaka、Chikuda Hirotaka
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 9144-9144
- DOI
  10.1038/s41598-019-45742-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-15H05906, KAKENHI-PROJECT-17H04311
[Journal Article] Risk Factors for Rapidly Progressive Neurological Deterioration in Cervical Spondylotic Myelopathy2019
- Author(s)
  Takasawa Eiji、Sorimachi Yasunori、Iizuka Yoichi、Tsunoda Daisuke、Mieda Tokue、Iizuka Haku、Chikuda Hirotaka
- Journal Title
  
  SPINE
  
  Volume: 44 Issue: 12 Pages: E723-E730
- DOI
  10.1097/brs.0000000000002969
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04311
[Journal Article] Unusual Painful Muscle Spasm in a Dialysis-Dependent Patient with Progressive Cervical Kyphosis2019
- Author(s)
  Tsunoda Daisuke、Iizuka Yoichi、Mieda Tokue、Iizuka Haku、Chikuda Hirotaka
- Journal Title
  
  Case Reports in Orthopedics
  
  Volume: 2019 Pages: 1-4
- DOI
  10.1155/2019/7062568
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04311
[Journal Article] Long-term patient reported outcomes of elbow, wrist and hand surgery for rheumatoid arthritis2018
- Author(s)
  Okura Chisa、Ishikawa Hajime、Abe Asami、Yonemoto Yukio、Okamura Koichi、Suto Takahito、Oyakawa Tomo、Miyagawa Yusuke、Otani Hiroshi、Ito Satoshi、Kobayashi Daisuke、Nakazono Kiyoshi、Murasawa Akira、Takagishi Kenji、Chikuda Hirotaka
- Journal Title
  
  International Journal of Rheumatic Diseases
  
  Volume: 21 Issue: 9 Pages: 1701-1708
- DOI
  10.1111/1756-185x.13340
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04311
[Journal Article] Phase I clinical trial of percutaneous cryoablation for osteoid osteoma2018
- Author(s)
  Miyazaki Masaya、Saito Kenichi、Yanagawa Takashi、Chikuda Hirotaka、Tsushima Yoshito
- Journal Title
  
  Japanese Journal of Radiology
  
  Volume: 36 Issue: 11 Pages: 669-675
- DOI
  10.1007/s11604-018-0768-6
- NAID
  50013030588
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04311
[Journal Article] The three-year efficacy of iguratimod in clinical daily practice in patients with rheumatoid arthritis2018
- Author(s)
  Suto Takahito、Yonemoto Yukio、Okamura Koichi、Sakane Hideo、Takeuchi Kimihiko、Tamura Yasuyuki、Kaneko Tetsuya、Ayabe Keio、Chikuda Hirotaka
- Journal Title
  
  Modern Rheumatology
  
  Volume: Aug 10 Issue: 5 Pages: 1-7
- DOI
  10.1080/14397595.2018.1510879
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04311
[Journal Article] Short-term daily teriparatide in patients with rheumatoid arthritis2017
- Author(s)
  Kaneko Tetsuya、Okamura Koichi、Yonemoto Yukio、Okura Chisa、Suto Takahito、Tachibana Masahiro、Tamura Yasuyuki、Inoue Makoto、Chikuda Hirotaka
- Journal Title
  
  Mod Rheumatol.
  
  Volume: 14 Issue: 3 Pages: 1-6
- DOI
  10.1080/14397595.2017.1362093
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04311
[Journal Article] Direct evidence of central nervous system axonal damage in patients with postoperative delirium: A preliminary study of pNF-H as a promising serum biomarker2017
- Author(s)
  Inoue Reo、Sumitani Masahiko、Ogata Toru、Chikuda Hirotaka、Matsubara Takehiro、Kato So、Shimojo Nobutake、Uchida Kanji、Yamada Yoshitsugu
- Journal Title
  
  Neurosci Lett.
  
  Volume: 653 Pages: 39-44
- DOI
  10.1016/j.neulet.2017.05.023
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04311
[Journal Article] Morphological characteristics of cervical spine in patients with athetoid cerebral palsy and the accuracy of pedicle screw placement2014
- Author(s)
  Kato S, Shoda N, Chikuda H, Seichi A, Takeshita K
- Journal Title
  
  Spine
  
  Volume: 39(8)
- Data Source
  KAKENHI-PROJECT-23390358
[Journal Article] Incidence and risk factors for mortality of vertebral osteomyelitis : a retrospective analysis using the Japanese diagnosis procedure combination database2013
- Author(s)
  Akiyama T, Chikuda H, Yasunaga H, Horiguchi H, Fushimi K, Saita K
- Journal Title
  
  BMJ Open
  
  Volume: 3(3)
- Data Source
  KAKENHI-PROJECT-23390358
[Journal Article] A novel disease-modifying osteoarthritis drug targeting Runx12013
- Author(s)
  Yano F, Hojo H, Ohba S, Fukai A, Hosaka Y, Ikeda T, Saito T, Hirata M, Chikuda H, Takato T, Kawaguchi H, Chung UI
- Journal Title
  
  Ann Rheum Dis
  
  Volume: 72 Pages: 748-53
- Data Source
  KAKENHI-PROJECT-23390358
[Journal Article] A novel disease-modifying osteoarthritis drug candidate targeting Runx1.2013
- Author(s)
  Yano F, Chikuda H, et al.
- Journal Title
  
  Ann Rheum Dis
  
  Volume: 72 Pages: 748-753
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390358
[Journal Article] A novel disease-modifying osteoarthritis drug candidate targeting Runx1.2013
- Author(s)
  Yano, F. et al.
- Journal Title
  
  Ann Rheum Dis.
  
  Volume: 72 Issue: 5 Pages: 748-753
- DOI
  10.1136/annrheumdis-2012-201745
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390416, KAKENHI-PROJECT-22689052, KAKENHI-PROJECT-23390358, KAKENHI-PROJECT-23659710, KAKENHI-PROJECT-24592254, KAKENHI-PROJECT-24659665, KAKENHI-PROJECT-25462358, KAKENHI-PROJECT-25462359, KAKENHI-PROJECT-25713052
[Journal Article] Mortality and morbidity in dialysis-dependent patients undergoing spinal surgery : analysis of a national administrative database in Japan2012
- Author(s)
  Chikuda H, Yasunaga H, Horiguchi H, Takeshita K, Kawaguchi H, Matsuda S, Nakamura K
- Journal Title
  
  J Bone Joint Surg Am
  
  Volume: 94(5) Pages: 433-8
- Data Source
  KAKENHI-PROJECT-23390358
[Journal Article] Mortality and morbidity in dialysis-dependent patients undergoing spinal surgery : analysis of a national administrative database in Japan2012
- Author(s)
  Chikuda H, et al.
- Journal Title
  
  J Bone Joint Surg Am
  
  Volume: 94 Pages: 433-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390358
[Journal Article] The normative score and the cut-off value of the Oswestry Disability Index (ODI)2012
- Author(s)
  Tonosu J, Chikuda H, et al.
- Journal Title
  
  Eur Spine J
  
  Volume: (E-pub)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390415
[Journal Article] Radiographical risk factors for major intraoperative blood loss during laminoplasty in patients with ossification of the posterior longitudinal ligament2012
- Author(s)
  Kato S, Chikuda H, Seichi A, Ohtsu H, Kimura A, Toyama Y
- Journal Title
  
  Spine (Phila Pa 1976)
  
  Volume: 37(25)
- Data Source
  KAKENHI-PROJECT-23390358
[Journal Article] Mortality and morbidity in dialysis-dependent patients undergoing spinal surgery: analysis of a national administrative database in Japan.2012
- Author(s)
  Chikuda H, et al.
- Journal Title
  
  J Bone Joint Surg Am.
  
  Volume: 94 Pages: 433-438
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390358
[Journal Article] The normative score and the cut-off value of the Oswestry Disability Index (ODI)2012
- Author(s)
  Tonosu J, Chikuda H, et al.
- Journal Title
  
  Eur Spine J
  
  Volume: (E-pub)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390358
[Journal Article] Normative score and cut-off value of the Neck Disability Index2012
- Author(s)
  Kato S, Takeshita K, Matsudaira K, Tonosu J, Hara N, Chikuda H
- Journal Title
  
  J Orthop Sci
  
  Volume: 17(6) Pages: 687-93
- Data Source
  KAKENHI-PROJECT-23390358
[Journal Article] Mortality and morbidity in dialysis-dependent patients undergoing spinal surgery : analysis of a national administrative database in Japan2012
- Author(s)
  Chikuda H, et al.
- Journal Title
  
  J Bone Joint Surg Am
  
  Volume: 94 Pages: 433-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390415
[Journal Article] Use of Doppler ultrasonography to detect an elusive communication of a spinal extradural arachnoid cyst2011
- Author(s)
  Kanetaka M, Chikuda H, et al.
- Journal Title
  
  J Clin Neurosci
  
  Volume: 18 Pages: 863-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390415
[Journal Article] Postsurgical spinal magnetic resonance imaging with iterative decomposition of water and fat with echo asymmetry and least-squares estimation.2011
- Author(s)
  Murakami M, Chikuda H, et al.
- Journal Title
  
  J Comput Assist Tomogr
  
  Volume: 35 Pages: 16-20
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390415
[Journal Article] Acute cervical spinal cord injury complicated by preexisting ossification of the posterior longitudinal ligament : a multicenter study2011
- Author(s)
  Chikuda H, et al.
- Journal Title
  
  Spine
  
  Volume: 36 Pages: 1453-8
- NAID
  10030716761
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390358
[Journal Article] Acute cervical spinal cord injury complicated by preexisting ossification of the posterior longitudinal ligament : a multicenter study2011
- Author(s)
  Chikuda H, et al.
- Journal Title
  
  Spine
  
  Volume: 36 Pages: 1453-8
- NAID
  10030716761
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390415
[Journal Article] Use of Doppler ultrasonography to detect an elusive communication of a spinal extradural arachnoid cyst2011
- Author(s)
  Kanetaka M, Chikuda H, et al.
- Journal Title
  
  J Clin Neurosci
  
  Volume: 18 Pages: 863-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390358
[Journal Article] Acute Cervical Spinal Cord Injury Complicated by Pre-existing Ossification of the Posterior Longitudinal Ligament : A Multi-center Study.2011
- Author(s)
  Chikuda H, et al.
- Journal Title
  
  Spine
  
  Volume: (Epub)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390415
[Journal Article] Acute cervical spinal cord injury complicated by pre-existing ossification of the posterior longitudinal ligament : A multi-center study2011
- Author(s)
  Chikuda H, et al
- Journal Title
  
  Spine
  
  Volume: 36 Issue: 18 Pages: 1453-1458
- DOI
  10.1097/brs.0b013e3181f49718
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591930
[Journal Article] Ossification of the posterior atlantoaxial membrane associated with an os odontoideum : a case report2011
- Author(s)
  Ohya J, Chikuda H, et al.
- Journal Title
  
  J Orthop Surg
  
  Volume: 19 Pages: 392-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390358
[Journal Article] Is a Right Pedicle Screw Always Away from the Aorta in Scoliosis?2011
- Author(s)
  Takeshita K, Chikuda H, et al.
- Journal Title
  
  Spine
  
  Volume: (Epub)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390415
[Journal Article] Ossification of the posterior atlantoaxial membrane associated with anos odontoideum : a case report2011
- Author(s)
  Ohya J, Chikuda H, et al.
- Journal Title
  
  J Orthop Surg
  
  Volume: 19 Pages: 392-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390415
[Journal Article] Neurological complications of cervical laminoplasty for patients with ossification of the posterior longitudinal ligament-A multi-instituitional retrospective study-2011
- Author(s)
  Seichi A, Chikuda H, et al.
- Journal Title
  
  Spine
  
  Volume: (Epub)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390415
[Journal Article] Correlation between pyramidal signs and the severity of cervical myelopathy.2010
- Author(s)
  Chikuda H, et al.
- Journal Title
  
  Eur Spine J
  
  Volume: 19 Pages: 1684-1689
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390415
[Journal Article] Correlation between pyramidal signs and the severity of cervical myelopathy.2010
- Author(s)
  Chikuda, et al.
- Journal Title
  
  Eur Spine J. (E-pub)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390415
[Journal Article] Intraoperative ultrasonographic evaluation of posterior decompression via laminoplasty in patients with cervical ossification of the posterior longitudinal ligament : correlation with 2-year follow-up results.2010
- Author(s)
  Seichi A, Chikuda H, et al.
- Journal Title
  
  J Neurosurg Spine
  
  Volume: 13 Pages: 47-51
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390415
[Journal Article] Long-term follow-up of the progression of ossification of the posterior longitudinal ligament.2010
- Author(s)
  Murakami M, Chikuda H, et al.
- Journal Title
  
  J Neurosurg Spine
  
  Volume: 12 Pages: 577-579
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390415
[Journal Article] New parameters to represent the position of the aorta relative to the spine for pedicle screw placement.2010
- Author(s)
  Takeshita K, Chikuda H, et al.
- Journal Title
  
  Eur Spine J
  
  Volume: 19 Pages: 815-820
- NAID
  10027068883
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390415
[Journal Article] New parameters to represent the position of the aorta relative to the spine for pedicle screw placement2010
- Author(s)
  Takeshita K, Chikuda H, et al.
- Journal Title
  
  Eur Spine J (E-pub)
- NAID
  10027068883
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390415
[Journal Article] Aorta movement in patients with scoliosis after posterior surgery.2010
- Author(s)
  Takeshita K, Chikuda H, et al.
- Journal Title
  
  Spine
  
  Volume: 35
- NAID
  10028263694
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390415
[Journal Article] Modified fenestration with restorative spinoplasty for lumbar spinal stenosis.2009
- Author(s)
  Matsudaira K, Chikuda H, et al.
- Journal Title
  
  J Neurosurg Spine 10
  
  Pages: 587-94
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390415
[Journal Article] Diameter, length, and direction of pedicle screws for scoliotic spine : analysis by multiplanar reconstruction of computed tomography.2009
- Author(s)
  Takeshita K, Chikuda H, et al.
- Journal Title
  
  Spine 34
  
  Pages: 798-803
- NAID
  10027240750
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390415
[Journal Article] Sleep apnea in rheumatoid arthritis patients with occipitoce rvical lesions : the prevalence and associated radiographic features2009
- Author(s)
  Shoda N, Chikuda H, et al.
- Journal Title
  
  Eur Spine J. 18
  
  Pages: 905-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390415
[Journal Article] Phosphorylation of GSK-3β by cGMP-dependent protein kinase II promotes hypertrophic differentiation of murine chondrocytes.2008
- Author(s)
  Kawasaki Y, Kugimiya F, Chikuda H, Kamekura S, Ikeda T, Kawamura N, Saito T, Shinoda Y, Higashikawa A, Yano F, Ogasawara T, Ogata N, Hoshi K, Hofmann F, Woodgett JR, Nakamura K, Chung UI, Kawaguchi H
- Journal Title
  
  J Clin Invest 118
  
  Pages: 2506-2515
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591775
[Journal Article] Osteoarthritis development in novel exper imental mouse models induced by knee joint instability.2005
- Author(s)
  Kamekura S, Hoshi K, Shimoaka T, Chung U, Chikuda H, Yamada T, Uchida M, Ogata N, Seichi A, Nakamura K, Kawaguchi H.
- Journal Title
  
  Osteoarthritis Cartilage 13(7)
  
  Pages: 632-641
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390452
[Journal Article] The canonical Wnt signaling pathway promotes chondrocyte differentiation in a Sox9-dependent manner.2005
- Author(s)
  Yano F, Kugiyama F, Ohba S, Ikeda T, Chikuda H, Chung U
- Journal Title
  
  Biochem Biophys Res Commun 333(4)
  
  Pages: 1300-1308
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390452
[Journal Article] The canonical Wnt signaling pathway promotes chondrocyte differentiation in a Sox9-dependent manner.2005
- Author(s)
  Yano F, Kugimiya F, Ohba S, Ikeda T, Chikuda H, Ogasawara T, Ogata N, Takato T, Nakamura K, Kawaguchi H, Chung U.
- Journal Title
  
  Biochem Biophys Res Commun 333(4)
  
  Pages: 1300-1308
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390452
[Journal Article] Involvement of endogenous bone morphogenetic protein (BMP)2 and BMP6 in bone formation.2005
- Author(s)
  Kugimiya F, Kawaguchi H, Kamekura S, Chikuda H, Ohba S, Yano F, Ogata N, Katagiri T, Harada Y, Azuma Y, Nakamura K, Chung U.
- Journal Title
  
  J Biol Chem 280
  
  Pages: 35704-35712
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390452
[Journal Article] Osteoarthritis development in novel experimental mouse models induced by knee joint instability.2005
- Author(s)
  Kamekura S, S Hoshi, Shimoaka T, Chung U, Chikuda H
- Journal Title
  
  Osteoarthritis Cartilage 13(7)
  
  Pages: 632-641
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390452
[Journal Article] Cyclic GMP-dependent kinase II is a molecular switch from proliferation to hypertrophic differentiation of chondrocytes2004
- Author(s)
  Chikuda H, Kugimiya F, Ikeda T, Komeda K, Chung U
- Journal Title
  
  Genes Dev 18
  
  Pages: 2418-2429
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390452
[Journal Article] Cyclic GMP-dependent kinase II is a molecular switch from proliferation to hypertrophic differentiation of chondrocytes.2004
- Author(s)
  Chikuda H, Kugimiya F, Ikeda T, Ogasawara T, Shimoaka T, Kawano H, Kamekura S, Tsuchida A, Yokoi N, Nakamura K, Komeda K, Chung U, Kawaguchi H.
- Journal Title
  
  Genes Dev 18
  
  Pages: 2418-2429
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390452
[Journal Article] Distinct Role of Smad Pathways and p38 Pathways in Cartilage-specific Gene Expression in Synovial Fibroblasts.2004
- Author(s)
  Seto H, Kamekura S, Miura T, Yamamoto A, Chikuda H, Ogata T, Hiraoka H, Nakamura K, Kurosawa H, Chung U, Kawaguchi H, Tanaka S.
- Journal Title
  
  J Clin Invest 113
  
  Pages: 718-726
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390452
[Presentation] Cerebrospinal fluid biomarkers for lumbar spinal stenosis identified by high-resolution mass spectrometry2019
- Author(s)
  Yoichi Iizuka, Koji L Ode, Hirotaka Chikuda
- Organizer
  2019 Annual meeting of Orthopedic Research Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15653
[Presentation] cGMP-dependent kinase II (cGKII)はGSK3βをリン酸化・不活化することによって軟骨細胞の肥大分化を制御する2010
- Author(s)
  川崎洋介、釘宮典孝、筑田博隆、池田敏之、斎藤琢、矢野文子、中村耕三、鄭雄一、川口浩
- Organizer
  第23回日本軟骨代謝学会
- Place of Presentation
  鹿児島県医師会館、鹿児島
- Data Source
  KAKENHI-PROJECT-20591775
[Presentation] cGKIIはGSK3βをリン酸化することによって軟骨細胞の肥大分化を制御する2009
- Author(s)
  川崎洋介、釘宮典孝、筑田博隆、中村耕三、鄭雄一、川口浩
- Organizer
  第82回日本整形外科学会学術総会
- Place of Presentation
  福岡国際会議場、福岡
- Data Source
  KAKENHI-PROJECT-20591775
[Presentation] Cyclic GMP-dependent protein kinase II promotes chondrocyte hypertrophy and skeletal growth.2009
- Author(s)
  Kawaguchi H, Chikuda H, Kawasaki Y, Hofmann F
- Organizer
  4th International Conference on cGMP.
- Place of Presentation
  Rosensburg, Germany.
- Data Source
  KAKENHI-PROJECT-20591775
[Presentation] Cyclic GMP-dependent protein kinase II promotes chondrocyte hypertrophy and skeletal growth2009
- Author(s)
  Kawaguchi H, Chikuda H, Kawasaki Y, Hofmann F
- Organizer
  4th International Conference on cGMP
- Place of Presentation
  Rosensburg, Germany
- Data Source
  KAKENHI-PROJECT-21591930

1. KAWAGUCHI Hiroshi (40282660)

# of Collaborated Projects: 9 results

# of Collaborated Products: 12 results
2. OGATA Naoshi (10361495)

# of Collaborated Projects: 9 results

# of Collaborated Products: 0 results
3. OGASAWARA Toru (20359623)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
4. ABE Masanobu (10392333)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
5. MORO Toru (20302698)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
6. ITO Hideya (30436464)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
7. CHUNG Ung-il (30345053)

# of Collaborated Projects: 3 results

# of Collaborated Products: 8 results
8. MATSUBARA Takehiro (40361498)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
9. NAKAMURA Kouzou (60126133)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
10. IKEDA Toshiyuki (80322759)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
11. YANO Fumiko (80529040)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
12. MIURA Toshiki (20376479)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. FUJIHARA Yuko (50466744)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. ABE Takahiro (20383250)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
15. INOKUCHI Takato (80587775)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
16. TAKETOMI Shuji (70570018)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
17. SAITO Taku (30456107)

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18. Matsubayashi Yoshitaka (50747962)

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19. Oshima Yasushi (50570016)

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20. 緒方徹 (00392192)

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21. 谷口優樹 (80722165)

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22. 森良之 (70251296)

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23. 羽毛田慈之 (90164772)

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24. 岡邨興一 (90527722)

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25. 設楽仁 (20588652)

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26. TAKEDA Hideki (90456111)

# of Collaborated Projects: 1 results

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27. OHASHI Satoru (20466767)

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# of Collaborated Products: 0 results
28. TAKATO Tsuyoshi (90171454)

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29. YAMAGAMI Ryota (00722191)

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30. ITAKA Keiji (60292926)

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31. 唐司寿一 (40597762)

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32. 森崎裕 (30508099)

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33. 岡敬之 (60401064)

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34. 乾洋 (60583119)

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35. 小牧裕司 (10548499)

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36. 石原一彦 (90193341)

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37. 高取吉雄 (40179461)

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38. 大嶋浩文 (00622359)

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39. 早川謙太郎 (20770697)

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40. 大出晃士 (40612122)

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41. 田中栄 (50282661)

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42. 柳川天志 (40400725)

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43. 中島崇仁 (70375559)

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44. 高嶺周平 (50868916)

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45. 一ノ瀬剛 (70742550)

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46. 鯉淵典之 (80234681)

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47. 冨田洋介 (10803158)

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48. 佐々木毅志 (50834446)

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49. 高澤英嗣 (70868695)

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50. 住谷昌彦 (80420420)

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51. 田鹿毅 (30571567)

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52. 矢富裕

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Chikuda Hirotaka 筑田 博隆

CHIKUDA Hirotaka 筑田 博隆

筑田 博隆 チクダ ヒロタカ

Research Projects

Research Products

Co-Researchers

高齢頚髄損傷の治療成績改善にむけた非侵襲血圧維持療法BP augmentationの開発Principal Investigator

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骨巨細胞腫に対するヒトRANKLモノクローナル抗体による光免疫療法の開発Principal Investigator

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Comprehensive research for molecular regulation of development, homeostasis, and degeneration of spinePrincipal Investigator

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Cerebrospinal Fluid Biomarkers for Lumbar Spinal Stenosis Identified by an Exhaustive search with High-Resolution Mass SpectrometryPrincipal Investigator

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Chikuda Hirotaka 筑田博隆

CHIKUDA Hirotaka 筑田博隆

筑田博隆チクダヒロタカ