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Hyodo Mamoru  兵藤 守

ORCIDConnect your ORCID iD *help
… Alternative Names

HYODO Mamoru  兵頭 守

HYOUDOU Mamoru  兵藤 守

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Researcher Number 30548186
Other IDs
External Links
Affiliation (Current) 2025: 大阪公立大学, 研究推進機構 , 特任准教授
Affiliation (based on the past Project Information) *help 2022 – 2024: 大阪公立大学, 研究推進機構, 特任准教授
2020 – 2021: 大阪府立大学, 研究推進機構, 特認准教授
2014 – 2016: 愛知工業大学, 工学部, 講師
2013: 北海道大学, 薬学研究科(研究院), その他
2013: 北海道大学, 薬学研究院, 特任助教
2012: 北海道大学, 大学院・薬学研究院, 特任助教
2011 – 2012: 北海道大学, 薬学研究科(研究院), 特任助教
Review Section/Research Field
Principal Investigator
Tumor therapeutics / Biomedical engineering/Biological material science
Except Principal Investigator
Basic Section 33020:Synthetic organic chemistry-related / Biomedical engineering/Biomaterial science and engineering / Drug development chemistry / Medium-sized Section 33:Organic chemistry and related fields / Chemistry related to living body
Keywords
Principal Investigator
リポソーム / DDS / YSK05 / c-di-GMP / ドラッグデリバリーシステム / アジュバント / ガン免疫療法 / 核酸 / 免疫 / がん … More / 内在化 / 脈管形成阻害 / SELEX / Troponin T / active targeting / 腫瘍血管内皮細胞 / リガンド / アプタマー / バイオコンジュゲート材料 … More
Except Principal Investigator
ミトコンドリア / C-H 官能基化 / サルフェートラジカル / 光触媒 / C-H官能基化 / 薬物送達システム / C=C結合の酸化的開裂 / C-Hチオレーション / ラジカル極性効果 / タングステートアニオン / 水素引き抜き反応 / デカタングステート / ラジカル反応 / マクロバッチ反応 / 異相系触媒 / 異相系媒体 / マイクロバッチ反応 / ドロップレット / 超微量有機合成 / 生理活性 / ワクチン / Riboswitch / 癌 / 核酸 / c[G(2'-5')pA(3'-5')p] / c[G(3'-5')pA(3'-5')p] / がん免疫療法 / ガン免疫療法 / がん / バイオフィルム / 免疫 / STING / がん細胞増殖抑制 / 免疫活性 / 2',3'-cGAMP / c-di-GMP / 環状ジヌクレオチド / 機能性核酸 / KALA / 核送達 / パッケージング / 細胞内動態制御 / バイセル / 自己活性化システム / ハイドロダイナミクス法 / ミトコンドリア送達 / 還元環境応答性 / pH-感受性カチオニック脂質 / ナノパッケージング / 核内動態制御 / マイクロ流路 / MEND / ナノマシン / 機能性人工核酸 / 2型糖尿病 / 疾患モデルマウス / 2型糖尿病 / ナノメディスン / 薬物送達 / 核酸医薬 Less
  • Research Projects

    (10 results)
  • Research Products

    (39 results)
  • Co-Researchers

    (28 People)
  •  Efficient Functionalization of C-H Bonds by Polar Radical Catalyst

    • Principal Investigator
      柳 日馨
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 33020:Synthetic organic chemistry-related
    • Research Institution
      Osaka Metropolitan University
  •  Bare-Minimum Organic Synthesis by Droplet

    • Principal Investigator
      Ryu Ilhyong
    • Project Period (FY)
      2020 – 2021
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 33:Organic chemistry and related fields
    • Research Institution
      Osaka Prefecture University
  •  Site-Selective C-H Functionalization by Photo-catalyst

    • Principal Investigator
      Ryu Ilhyong
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 33020:Synthetic organic chemistry-related
    • Research Institution
      Osaka Prefecture University
  •  Development of a nanoparticle to release nucleic acids in a mitochondrial environment

    • Principal Investigator
      YAMADA Yuma
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Biomedical engineering/Biomaterial science and engineering
    • Research Institution
      Hokkaido University
  •  脂質修飾c-di-GMP 封入MENDによるガン免疫治療Principal Investigator

    • Principal Investigator
      兵藤 守
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Tumor therapeutics
    • Research Institution
      Aichi Institute of Technology
  •  Development of nanomachine for mitochondrial gene therapy targeted to cells derived from mitochondrial disease patients

    • Principal Investigator
      YAMADA Yuma
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biomedical engineering/Biomaterial science and engineering
    • Research Institution
      Hokkaido University
  •  Investigation on biological activity of cyclic dinucleotides and elucidation of mechanism how the activity is expressed, directing toward invention of new immunostimulants

    • Principal Investigator
      Hayakawa Yoshihiro
    • Project Period (FY)
      2012 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Chemistry related to living body
    • Research Institution
      Aichi Institute of Technology
  •  Investigation of nucleic acid type ligand which can use in vivoPrincipal Investigator

    • Principal Investigator
      HYODO Mamoru
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Biomedical engineering/Biological material science
    • Research Institution
      Hokkaido University
  •  MENDで拓く遺伝子治療への道:遺伝子の運び屋からナノマシンへ

    • Principal Investigator
      原島 秀吉
    • Project Period (FY)
      2010 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Drug development chemistry
    • Research Institution
      Hokkaido University
  •  Study on the innovative molecular-targeting medicine based on the nano-DDS encapsulating intelligent artificial oligonucleotides

    • Principal Investigator
      SASAKI Shigeki
    • Project Period (FY)
      2009 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Drug development chemistry
    • Research Institution
      Kyushu University

All 2023 2022 2021 2020 2016 2015 2014 2013 2012 2011 Other

All Journal Article Presentation Patent

  • [Journal Article] Photocatalytic Oxidative Cleavage of Alkenes by Molecular Oxygen: Reaction Scope, Mechanistic Insights, and Flow Application2023

    • Author(s)
      Yi-Lun Shih, Yen-Ku Wu, Mamoru Hyodo, Ilhyong Ryu
    • Journal Title

      J. Org. Chem.

      Volume: 88 Issue: 10 Pages: 6548-6552

    • DOI

      10.1021/acs.joc.2c02429

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K23350
  • [Journal Article] Photocatalytic C(sp3)-H thiolation by a double SH2 strategy using thiosulfonates2023

    • Author(s)
      Nobukazu Taniguchi, Mamoru Hyodo, Lin-Wei Pan, Ilhyong Ryu
    • Journal Title

      Chem. Commun.

      Volume: 59 Issue: 100 Pages: 14859-14862

    • DOI

      10.1039/d3cc05149h

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K23350
  • [Journal Article] Improved efficiency of photo-induced synthetic reactions enabled by advanced photo flow technologies2022

    • Author(s)
      Fukuyama Takahide、Kasakado Takayoshi、Hyodo Mamoru、Ryu Ilhyong
    • Journal Title

      Photochemical & Photobiological Sciences

      Volume: - Issue: 5 Pages: 761-775

    • DOI

      10.1007/s43630-021-00151-6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19H02722, KAKENHI-PROJECT-23K23350
  • [Journal Article] Using High-Power UV-LED to Accelerate a Decatungstate-Anion-Catalyzed Reaction: A Model Study for the Quick Oxidation of Benzyl Alcohol to Benzoic Acid Using Molecular Oxygen.2021

    • Author(s)
      Hyodo, Mamoru ; Iwano, Hitomi; Kasakado, Takayoshi; Fukuyama, Takahide ; Ryu, Ilhyong
    • Journal Title

      Micromachines

      Volume: 12 Issue: 11 Pages: 1307-1307

    • DOI

      10.3390/mi12111307

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K21199, KAKENHI-PROJECT-19H02722
  • [Journal Article] Greener Synthesis of Pristane by Flow Dehydrative Hydrogenation of Allylic Alcohol Using a Packed- Bed Reactor Charged by Pd/C as a Single Catalyst2021

    • Author(s)
      Kasakado, Takayoshi; Hirobe, Yuki; Furuta, Akihiro; Hyodo, Mamoru; Fukuyama, Takahide; Ryu, Ilhyong
    • Journal Title

      Molecules

      Volume: 26 Issue: 19 Pages: 5845-5853

    • DOI

      10.3390/molecules26195845

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19H02722
  • [Journal Article] Electron-Catalyzed Aminocarbonylation: Synthesis of α,β-Unsaturated Amides from Alkenyl Iodides, CO, and Amines2021

    • Author(s)
      Picard, Baptiste ; Fukuyama, Takahide ; Bando, Takanobu; Hyodo, Mamoru; Ryu, Ilhyong
    • Journal Title

      Organic Letters

      Volume: 23 Issue: 24 Pages: 9505-9509

    • DOI

      10.1021/acs.orglett.1c03714

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19H02722
  • [Journal Article] Flow Friedel-Crafts alkylation of 1-adamantanol with arenes using HO-SAS as an immobilized acid catalyst2020

    • Author(s)
      T. Kasakado, M. Hyodo, A. Furuta, A. Kamardine, I. Ryu, T. Fukuyama
    • Journal Title

      J. Chin. Chem. Soc.

      Volume: 67 Issue: 12 Pages: 2253-2257

    • DOI

      10.1002/jccs.202000518

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K21199, KAKENHI-PROJECT-19H02722
  • [Journal Article] A lipid nanoparticle for the efficient delivery of siRNA to dendritic cells.2016

    • Author(s)
      Warashina S, Nakamura T, Sato Y, Fujiwara Y, Hyodo M, Hatakeyama H, Harashima H
    • Journal Title

      J Control Release.

      Volume: 225 Pages: 183-191

    • DOI

      10.1016/j.jconrel.2016.01.042

    • NAID

      120005981350

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26830101, KAKENHI-PROJECT-26713002
  • [Journal Article] Novel pH-sensitive multifunctional envelope-type nanodevice for siRNA-based treatments for chronic HBV infection2016

    • Author(s)
      Yamamoto, N. Sato, Y. Munakata, T. Kakuni, M. Tateno, C. Sanada, T. Hirata, Y. Murakami, S. Tanaka, Y. Chayama, K. Hatakeyama, H. Hyodo, M. Harashima, H. Kohara, M.
    • Journal Title

      Journal of hepatology

      Volume: 64 Issue: 3 Pages: 547-455

    • DOI

      10.1016/j.jhep.2015.10.014

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K19120, KAKENHI-PROJECT-15H04739, KAKENHI-PROJECT-24590565, KAKENHI-PROJECT-26830101, KAKENHI-PUBLICLY-15H01272, KAKENHI-PROJECT-15K15293
  • [Journal Article] Relationship Between the Physicochemical Properties of Lipid Nanoparticles and the Quality of siRNA Delivery to Liver Cells2016

    • Author(s)
      Yusuke Sato, Hiroto Hatakeyama, Mamoru Hyodo, Hideyoshi Harashima
    • Journal Title

      Molecular Therapy

      Volume: 24 Issue: 4 Pages: 788-795

    • DOI

      10.1038/mt.2015.222

    • NAID

      120005906929

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K20831, KAKENHI-PROJECT-26830101
  • [Journal Article] New drug delivery system for liver sinusoidal endothelial cells for ischemia-reperfusion injury.2015

    • Author(s)
      Sano N, Tamura T, Toriyabe N, Nowatari T, Nakayama K, Tanoi T, Murata S, Sakurai Y, Hyodo M, Fukunaga K, Harashima H, Ohkohchi N.
    • Journal Title

      World J Gastroenterol.

      Volume: 21 Issue: 45 Pages: 12778-12786

    • DOI

      10.3748/wjg.v21.i45.12778

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26830101, KAKENHI-PROJECT-26293296
  • [Journal Article] Liposomes loaded with a STING pathway ligand, cyclic di-GMP, enhance cancer immunotherapy against metastatic melanoma.2015

    • Author(s)
      Nakamura T, Miyabe H, Hyodo M, Sato Y, Hayakawa Y, Harashima H.
    • Journal Title

      J Control Release

      Volume: 216 Pages: 149-157

    • DOI

      10.1016/j.jconrel.2015.08.026

    • NAID

      120005853062

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26830101, KAKENHI-PROJECT-24350087
  • [Journal Article] Mitochondrial delivery of Coenzyme Q via systemic administration using a MITO-Porter prevents ischemia/reperfusion injury in the mouse liver.2015

    • Author(s)
      Yamada Y, Nakamura K, Abe J, Hyodo M, Haga S, Ozaki M, Harashima H.
    • Journal Title

      Journal of controlled release

      Volume: 10 Pages: 86-95

    • DOI

      10.1016/j.jconrel.2015.06.037

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K09679, KAKENHI-PROJECT-26670591, KAKENHI-PROJECT-26830101, KAKENHI-PROJECT-26282131
  • [Journal Article] RNA Aptamers for Targeting Mitochondria Using a Mitochondria-Based SELEX Method2014

    • Author(s)
      Yuri Tawaraya, Mamoru Hyodo, Mst Naznin Ara, Yuma Yamada, Hideyoshi Harashima.
    • Journal Title

      Biological and Pharmaceutical Bulletin

      Volume: 37 Issue: 8 Pages: 1411-1415

    • DOI

      10.1248/bpb.b14-00112

    • NAID

      130004677537

    • ISSN
      0918-6158, 1347-5215
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25560219, KAKENHI-PROJECT-26282131
  • [Journal Article] RNAi-mediated gene knockdown and anti-angiogenic therapy of RCCs using a cyclic RGD-modified liposomal-siRNA system2014

    • Author(s)
      Yu Sakurai, Hiroto Hatakeyama, Yusuke Sato, Mamoru Hyodo, Hidetaka Akita, Noritaka Ohga, Kyoko Hida, Hideyoshi Harashima
    • Journal Title

      J. Control. Release

      Volume: 173 Pages: 110-118

    • DOI

      10.1016/j.jconrel.2013.10.003

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-11J05557, KAKENHI-PROJECT-21229002, KAKENHI-PUBLICLY-24107502, KAKENHI-PROJECT-25462909, KAKENHI-PROJECT-25893001, KAKENHI-PROJECT-26830101
  • [Journal Article] c-di-GMP Enhances Protective Innate Immunity in a Murine Model of Pertussis.2014

    • Author(s)
      S. Elahi, J. Van Kessel, T. G. Kiros, S. Strom, Y Hayakawa, M.Hyodo, L. A. Babiuk, and V. Gerdts
    • Journal Title

      PLOS ONE

      Volume: 9 Issue: 10 Pages: e109778-e109778

    • DOI

      10.1371/journal.pone.0109778

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24350087, KAKENHI-PROJECT-26830101
  • [Journal Article] Identification and expression of troponin T, a new marker on the surface of cultured tumor endothelial cells by aptamer ligand2014

    • Author(s)
      Ara MN., Hyodo M., Ohga N., Akiyama K., Hida K., Hida Y., Shinohara N., Harashima H
    • Journal Title

      Cancer Med

      Volume: 3 Issue: 4 Pages: 825-834

    • DOI

      10.1002/cam4.260

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24390324, KAKENHI-PROJECT-24791958, KAKENHI-PROJECT-25463106, KAKENHI-PROJECT-26830101
  • [Journal Article] RNA aptamers for targeting mitochondria using a mitochondria based SELEX method.2014

    • Author(s)
      Yuri Tawaraya, Mamoru Hyodo, Yuma Yamada, Hideyoshi Harashima
    • Journal Title

      Biol. Pharm. Bull.

      Volume: 37 Pages: 1411-1415

    • NAID

      130004677537

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26830101
  • [Journal Article] SMAD2 disruption in meuse pancreatic beta cells leads to islet hyperplasia and impaired insulin secretion due to the attenuation of ATP-sengitive K+ channel activity.2014

    • Author(s)
      Nomura M, Zhu HL, Wang L, Morinaga H, Takayanagi R, Teramoto N.
    • Journal Title

      Diabetologia

      Volume: 57 Issue: 1 Pages: 157-166

    • DOI

      10.1007/s00125-013-3062-2

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-12F02426, KAKENHI-PROJECT-21229002, KAKENHI-PROJECT-23390247, KAKENHI-PROJECT-23591356, KAKENHI-PROJECT-26282148, KAKENHI-PROJECT-26461383
  • [Journal Article] A new adjuvant delivery system ‘cyclic di-GMP/YSK05 liposome’ for cancer immunotherapy.2014

    • Author(s)
      Hiroko Miyabe, Mamoru Hyodo, Takashi Nakamura, Yusuke Sato, Yoshihiro Hayakawa, and Hideyoshi Harashima
    • Journal Title

      J. Controlled Release

      Volume: 184 Pages: 20-27

    • DOI

      10.1016/j.jconrel.2014.04.004

    • NAID

      120005512017

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24350087, KAKENHI-PROJECT-26830101
  • [Journal Article] An aptamer ligand based liposomal nanocarrier system that targets tumor endothelial cells2014

    • Author(s)
      Ara MN, Matsuda T, Hyodo M, Sakurai Y, Hatakeyama H, Ohga N, Hida K, Harashima H
    • Journal Title

      Biomaterials

      Volume: 35 Issue: 25 Pages: 7110-7120

    • DOI

      10.1016/j.biomaterials.2014.04.087

    • NAID

      120005512022

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25893001, KAKENHI-PROJECT-26830101
  • [Journal Article] Hepatic Monoacylglycerol 0-acyltransferase 1 as a Promising Therapeutic Target for Steatosis, Obesity, and Type 2 Diabetes2014

    • Author(s)
      Yasuhiro Hayashi, Erina Suemitsu, Kazuaki Kajimoto, Yusuke Sato, Afsana Akhter, Yu Sakurai, Hiroto Hatakeyama, Mamoru Hyodo, Noritada Kaji, Yoshinobu Baba, Hideyoshi Harashima
    • Journal Title

      Mol. Ther. Nucleic Acids

      Volume: 3 Pages: e154-e154

    • DOI

      10.1038/mtna.2014.4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-11J05557, KAKENHI-PROJECT-21229002, KAKENHI-PUBLICLY-24107502
  • [Journal Article] Intracellular observation of nanocarriers modified with a mitochondrial targeting signal peptide2013

    • Author(s)
      Eriko Kawamura, Yuma Yamada, Yukari Yasuzaki, Mamoru Hyodo and Hideyoshi Harashima.
    • Journal Title

      Journal of bioscience and bioengineering

      Volume: 116(5) Issue: 5 Pages: 634-637

    • DOI

      10.1016/j.jbiosc.2013.05.001

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-11J05438, KAKENHI-PROJECT-21229002, KAKENHI-PROJECT-23680053, KAKENHI-PROJECT-25560219
  • [Journal Article] An approach to transgene expression in liver endothelial cells using a liposome-based gene vector coated with hyaluronic acid2013

    • Author(s)
      Yamada Y, Hashida M, Hayashi Y, Tabata M, Hyodo M, Ara MN, Ohga N, Hida K, Harashima H.
    • Journal Title

      J Pharm Sci. (Wiley)

      Volume: 102 Pages: 3119-27

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229002
  • [Journal Article] The innate DNA sensor cGAS produces a non-canonical cyclic-di-nucleotide that activates human STING.2013

    • Author(s)
      Elie J. Diner, Dara L. Burdette, Stephen C. Wilson, Kathryn M. Monroe, Colleen A. Kellenberger, Mamoru Hyodo, Yoshihiro Hayakawa, Ming C. Hammond, and Russell E. Vance
    • Journal Title

      Cell Reports

      Volume: 3 Issue: 5 Pages: 1355-1361

    • DOI

      10.1016/j.celrep.2013.05.009

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24350087
  • [Journal Article] A comparative study between nanoparticle-targeted therapeutics and bioconjugates as obesity medication2013

    • Author(s)
      Hossen MN, Kajimoto K, Akita H, Hyodo M, Harashima H.
    • Journal Title

      J. Control. Release

      Volume: 171 Issue: 2 Pages: 104-12

    • DOI

      10.1016/j.jconrel.2013.07.013

    • NAID

      120005365904

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229002
  • [Journal Article] Gene Silencing via RNAi and siRNA quantification in Tumor Tissue using MEND, a Liposomal siRNA Delivery System2013

    • Author(s)
      Sakurai Y, Hatakeyama H, Sato Y, Hyodo M, Akita H, Harashima H
    • Journal Title

      Molecular Therapy

      Volume: (印刷中) Issue: 6 Pages: 1195-203

    • DOI

      10.1038/mt.2013.57

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-10J02352, KAKENHI-PROJECT-21229002, KAKENHI-PUBLICLY-24107502
  • [Journal Article] Vascular-targeted nanotherapy for obesity” Unexpected passive targeting mechanism to obese fat for the enhancement of active drug delivery.2012

    • Author(s)
      Hossen Md. Nazir
    • Journal Title

      Journal of Controlled Release

      Volume: 163 Issue: 2 Pages: 101-110

    • DOI

      10.1016/j.jconrel.2012.09.002

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659027, KAKENHI-PROJECT-23700552, KAKENHI-PROJECT-24350087
  • [Journal Article] Development of a novel DNAaptamer ligand targeting to primary culturedtumor endothelial cells by a cell-based SELEXmethod2012

    • Author(s)
      Mst. Naznin Ara, Mamoru Hyodo,Noritaka Ohga, Kyoko Hida, Hideyoshi Harashima
    • Journal Title

      PLoS One

      Volume: 7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23700552
  • [Journal Article] STING is a direct innate imune sensor of cyclic di-GMP.2011

    • Author(s)
      Dara L. Burdette, Kathryn M. Monroe, Katia Sotelo-Troha, Jeff S. Iwig, Barbara Eckert, Mamoru Hyodo, Yoshihiro Hayakawa, Russell E. Vance
    • Journal Title

      Nature

      Volume: 478 Issue: 7370 Pages: 515-519

    • DOI

      10.1038/nature10429

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23700552
  • [Patent] トロポニンTと結合するDNA、これを用いた腫瘍組織における血管新生および/または脈管形成抑制剤ならびにこれを用いた細胞内へ目的物質が取り込まれることを促進する剤2012

    • Inventor(s)
      アラ ナズニン,兵藤宣,畠山浩人,樋田京子,大賀則孝,原島秀吉
    • Industrial Property Rights Holder
      バイオメッドコア,アラ ナズニン,兵藤立,畠山浩人,樋田京子,大賀則孝,原島秀吉
    • Filing Date
      2012-06-21
    • Data Source
      KAKENHI-PROJECT-23700552
  • [Presentation] Investigation of tumor endothelial cell targeting aptamer and its application for drug delivery.2013

    • Author(s)
      M. Hyodo
    • Organizer
      The 16th Hokkaido University-Seoul National University Joint Symposium
    • Place of Presentation
      Seoul, Korea
    • Invited
    • Data Source
      KAKENHI-PROJECT-21229002
  • [Presentation] A new approach for innovative nanomedicine of type 2 diabetes in combination with DNA microarray and in vivo siRNA delivery2013

    • Author(s)
      Suemitsu E, Hayashi Y, Kajimoto K, Sato Y, Akhter A, Sakurai Y, Hatakeyama H, Hyodo M, Harashima H,
    • Organizer
      40th Annual Meeting & Exposition of the Controlled Release Society
    • Place of Presentation
      Honolulu, Hawaii, USA
    • Data Source
      KAKENHI-PROJECT-21229002
  • [Presentation] DNAマイクロアレイとin vivo siRNA送達システムの融合による新規2型糖尿病治療薬創出2013

    • Author(s)
      末光永理奈、林泰弘、梶本和昭、佐藤悠介、Afsana Akhter、櫻井遊、畠山浩人、兵藤守、加地範匡、馬場嘉信、原島秀吉
    • Organizer
      日本薬剤学会第28年会
    • Place of Presentation
      名古屋 (ウインクあいち)
    • Data Source
      KAKENHI-PROJECT-21229002
  • [Presentation] Investigation of RNA aptamers targetingmitochondria by mitochondria based SELEX.Abstract No.1492012

    • Author(s)
      Yuri Tawaraya, Mamoru Hyodo, YumaYamada and Hideyoshi Harashima
    • Organizer
      IS3NA XX intemationalroundtable
    • Place of Presentation
      Centre Mont-Royal Montreal,Canada
    • Data Source
      KAKENHI-PROJECT-23700552
  • [Presentation] Isolation of new DNA aptamers for pancreatic cancer cells2012

    • Author(s)
      Mamoru Hyodo
    • Organizer
      IS3NA XX international roundtable
    • Place of Presentation
      Centre Mont-Royal (Canada)
    • Data Source
      KAKENHI-PROJECT-23700552
  • [Presentation] Development of a new DNA aptamer against primary cultured tumor endothelial cells by a cell-based SELEX method to discover a new drug delivery system

    • Author(s)
      Mst Naznin Ara, Mamoru Hyodo, Noritaka Ohga, Kyoko Hida, Hideyoshi Harashima
    • Organizer
      AACR annual meeting 2012
    • Place of Presentation
      McCormick Place (USA)
    • Data Source
      KAKENHI-PROJECT-23700552
  • [Presentation] Synthesis and biological activity of cyclic dinucleotide diphosphorothioates

    • Author(s)
      Mamoru Hyodo, Shogo Ishiyama, Hiroaki Murai, Taichi Kamegaya, Michio Ohta, Stephen Lory, and Yoshihiro Hayakawa
    • Organizer
      The 41st International Symposium on Nucleic Acids Chemistry 2014
    • Place of Presentation
      Kitakyushu, Japan
    • Year and Date
      2014-11-05 – 2014-11-07
    • Data Source
      KAKENHI-PROJECT-24350087
  • [Presentation] Synthesis and biological activity of cG(2'–5')oA(3'–5')p

    • Author(s)
      Mamoru Hyodo, Masahito Inagaki, Hiroko Miyabe, Takashi Nakamura, Hideyoshi Harashima, and Yoshihiro Hayakawa
    • Organizer
      The 41st International Symposium on Nucleic Acids Chemistry 2014
    • Place of Presentation
      Kitakyushu, Japan
    • Year and Date
      2014-11-05 – 2014-11-07
    • Data Source
      KAKENHI-PROJECT-24350087
  • 1.  YAMADA Yuma (60451431)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 1 results
  • 2.  Ryu Ilhyong (80210821)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 3.  HARASHIMA Hideyoshi (00183567)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 4 results
  • 4.  AKITA Hidetaka (80344472)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  SASAKI Shigeki (10170672)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  NAGATSUGI Fumi (90208025)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  SHINDO Mitsuru (40226345)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  NOMURA Masatoshi (30315080)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 9.  Hayakawa Yoshihiro (50022702)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 10.  Nishimura Akiko (90609322)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  Ohta Michio (20111841)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 12.  中村 孝司 (20604458)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  馬場 嘉信 (30183916)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  篠原 康雄 (60226157)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  小暮 健太朗 (70262540)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  紙谷 浩之 (10204629)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  渡慶次 学 (60311437)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  松尾 保孝 (90374652)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  福山 高英 (60332962)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 20.  隅野 修平 (60783272)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  HIDA Kyoko
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 22.  HIDA Yasuhiro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 23.  ABE JIRO
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 24.  SATO Yusuke
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 25.  柳 曰馨
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 7 results
  • 26.  山本 直樹
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 27.  WANG Lixiang
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results
  • 28.  櫻井 遊
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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